Page last updated: 2024-08-21

methionine sulfoximine and ammonium hydroxide

methionine sulfoximine has been researched along with ammonium hydroxide in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	54 (51.43)	18.7374
1990's	28 (26.67)	18.2507
2000's	13 (12.38)	29.6817
2010's	9 (8.57)	24.3611
2020's	1 (0.95)	2.80

Authors

Authors	Studies
Karasawa, Y; Tasaki, I	2
Gest, H; Johansson, BC	1
Welbourne, TC	1
Cooper, AJ; Duffy, TE; Gelbard, AS; Gledhill, RF; McDonald, JM	1
Meyer, J; Vignais, PM	1
Haselkorn, R; Nagatani, HH	1
Hattori, A; Ohmori, M	1
Narins, RG; Relman, AS	1
Rowell, P; Stewart, WD	1
Wadoux, P; Welbourne, TC	1
Jones, BL; Monty, KJ	1
Chien, WS; Lockau, W; Meeks, JC; Schilling, N; Shaffer, PW; Wolk, CP	1
Benjamin, AM; Quastel, JH	1
Tabita, FR; Wang, X	1
Ertan, H	1
Brusilow, SW; Hirata, T; Koehler, RC; Takahashi, H; Traystman, RJ	1
Farrow, NA; Kanamori, K; Parivar, F; Ross, BD	2
Brusilow, SW; Koehler, RC; Takahashi, H; Traystman, RJ	2
Chance, WT; Fischer, JE; Zhang, FS	1
Hawkins, RA; Jessy, J	1
Abrol, YP; Chatterjee, SR; Kumar, PA	1
Bosman, DK; Bovée, WM; Chamuleau, RA; De Graaf, AA; Deutz, NE; Jörning, GG; Maas, MA; Van Eijk, HM; vd Hulst, RW	1
Cárdenas, J; Córdoba, F; Fernández, E; Galván, A	1
Murthy, CR; Ratnakumari, L	1
Kumar, HD; Mishra, AK; Pandey, AB	1
Iwasaki, Y; Konno, H; Sato, Y; Yamamoto, H; Yamamoto, T	1
Bachelard, HS; Bates, TE; Brooks, KJ; Gadian, DG; Kauppinen, RA; Williams, SR	1
Karasawa, Y; Nakata, C	2
Armitage, JP; Poole, PS	1
Colanduoni, J; Nissan, R; Villafranca, JJ	1
Kanemoto, RH; Ludden, PW	1
Aronson, AI; Strauch, MA; Zalkin, H	1
Mackerras, AH; Smith, GD	1
Helber, JT; Hirschberg, R; Johnson, TR; Yarbrough, LR	1
Flores, E; Guerrero, MG; Romero, JM	1
Fischer, JE; James, JH; Jonung, T; Peters, JC; Rigotti, P	1
Brackett, K; Fischer, JE; James, JH; Jonung, T; Rigotti, P	1
Brosnan, JT; Lanctin, H; Ross, BD	1
Meister, A; Weisbrod, RE	1
Meister, A; Ronzio, RA; Rowe, WB	1
Fontenelle, LJ; Henderson, JF	1
Cooney, D; Davis, R; Van Atta, G	1
Lund, P	1
Hindfelt, B	1
Meister, A	1
Preuss, HG; Weiss, FR	1
Folbergrová, J; Lowry, OH; Passonneau, JV; Schulz, DW	1
Dienstbier, Z; Jirácek, V; Kolousek, J; Zícha, B	1
Bagchi, SN; Rai, UN; Rao, VV; Singh, HN	1
Arp, DJ; Zumft, WG	1
Duong, N; Gougoux, A; Guern, C; Khoury, N; Vinay, P	1
Anderson, PM; Casey, CA	1
Murthy, CR; Subbalakshmi, GY	1
Alef, K; Hartmann, A; Kleiner, D	1
Areas, J; Preuss, HG; Singh Aujla, M; Slemmer Gaydos, D; Vertuno, LL	1
Barrio, JR; Douglas, A; Keen, RE; Krivokapich, J; Padgett, HC; Phelps, ME; Shine, KI; Watanabe, CR	1
Fischer, JE; James, JH; Jeppsson, B; Jonung, T; Peters, JC; Rigotti, P	1
Burris, RH; Sweet, WJ	1
Onstad, GR; Raabe, WA	1
Hansen, H; Huang, SC; Kuhl, DE; MacDonald, NS; Phelps, ME; Schelbert, HR; Selin, C	1
Preuss, HG	1
Bender, AS; Norenberg, MD	1
Bryła, J; Lietz, T	1
Aunins, J; Bibila, T; Buckland, B; Glazomitsky, K; Ranucci, C	1
Dejong, CH; Deutz, NE; Heeneman, S	1
Brookes, N	1
Hornsperger, JM; Knoedgen, B; Sablone, M; Sarhan, S; Seiler, N	1
Blei, AT; Butterworth, RF; Olafsson, S; Therrien, G	1
Deutz, NE; Heeneman, S	1
Brusilow, SW; Hirata, T; Kawaguchi, T; Koehler, RC; Traystman, RJ	2
Chung, JC; Kanamori, K; Kuo, EL; Ross, BD	1
Brusilow, SW; Koehler, RC; Sugimoto, H; Traystman, RJ; Wilson, DA	1
Brusilow, SW; Cork, LC; Hirata, T; Koehler, RC; Takahashi, H; Traystman, RJ; Willard-Mack, CL	1
Dunbar, AJ; Wheldrake, JF	1
Bender, AS; Isaacks, RE; Kim, CY; Norenberg, MD; Shi, YF	1
Kumari, P; Lakshminarayana, K; Narula, N; Sheoran, RK; Shukla, B; Sindhu, SS	1
Attwell, D; Grant, J; Marcaggi, P; Mort, D	1
STONE, WE; TEWS, JK	1
SCHENKER, S; WARREN, KS	1
Benz, AM; Ishikawa, M; Izumi, M; Izumi, Y; Matsukawa, M; Olney, JW; Zorumski, CF	1
Brusilow, SW; Kawaguchi, T; Koehler, RC; Traystman, RJ	1
Chew, SF; Goh, GS; Ip, YK; Leong, MW; Sim, MY; Wong, WP	1
McDonald, MD; Van Audekerke, J; Van Camp, N; Van der Linden, A; Vanhoutte, G; Veauvy, CM; Walsh, PJ	1
Cheng, HT; Chew, SF; Ip, YK; Lee, SM; Tng, YY; Wee, NL	1
Albrecht, J; Beresewicz, A; Hilgier, W; Maczewski, M; Oja, SS; Saransaari, P; Wegrzynowicz, M	1
Ahmad, JN; Akhtar, S; Khan, A; Sarkar, D	1
Chew, SF; Ip, YK; Lee, SM; Wong, WP	1
Gottschalk, S; Zwingmann, C	1
Chew, SF; Ip, YK; Tng, YY; Tok, CY; Wee, NL; Wong, FK; Wong, WP	1
Fukumura, T; Hosoi, R; Inoue, O; Nakao, R; Okada, M; Suzuki, K; Zhang, MR	1
Ballantyne, JS; Bernier, NJ; Robinson, JW; Sanderson, LA; Wright, PA	1
Albrecht, J; Norenberg, MD; Zielińska, M	1
Bak, LK; Dadsetan, S; Keiding, S; Leke, R; Ott, P; Schousboe, A; Sørensen, M; Vilstrup, H; Waagepetersen, HS	1
Cooper, AJ	1
Bak, LK; Dadsetan, S; Keiding, S; Kukolj, E; Ott, P; Schousboe, A; Sørensen, M; Vilstrup, H; Waagepetersen, HS	1
Bak, LK; Dadsetan, S; Fries, AW; Keiding, S; Ott, P; Schousboe, A; Simonsen, M; Sørensen, M; Vilstrup, H; Waagepetersen, HS	1
Abe, K; Ito, M; Momosaki, S; Tonomura, M	1
Giacomin, M; Wood, CM	1
Lee, GM; Noh, SM; Shin, S	1
Li, M; Liu, B; Zhu, X	1

Reviews

4 review(s) available for methionine sulfoximine and ammonium hydroxide

Article	Year
The control of ammonia production in the rat. The Medical clinics of North America, 1975, Volume: 59, Issue:3 Topics: Acidosis; Acute Disease; Aminooxyacetic Acid; Ammonia; Animals; Deamination; Glutamates; Glutamine; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kidney; Kidney Cortex; Kidney Medulla; Malates; Methionine Sulfoximine; Mitochondria; Phosphates; Phosphoenolpyruvate; Rats	1975
The specificity of glutamine synthetase and its relationship to substrate conformation at the active site. Advances in enzymology and related areas of molecular biology, 1968, Volume: 31 Topics: Amino Acids; Ammonia; Aspartic Acid; Binding Sites; Cyclohexanes; Glutamates; Glutamine; Ligases; Methionine Sulfoximine; Models, Chemical	1968
Glutamine as a mediator of ammonia neurotoxicity: A critical appraisal. Biochemical pharmacology, 2010, Nov-01, Volume: 80, Issue:9 Topics: Ammonia; Animals; Astrocytes; Brain; Cyclic GMP; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Hepatic Encephalopathy; Humans; Methionine Sulfoximine; Mitochondria; Nitric Oxide	2010
Possible treatment of end-stage hyperammonemic encephalopathy by inhibition of glutamine synthetase. Metabolic brain disease, 2013, Volume: 28, Issue:2 Topics: Ammonia; Animals; Brain; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Hepatic Encephalopathy; Homeostasis; Humans; Hyperammonemia; Liver; Liver Diseases; Liver Failure, Acute; Methionine Sulfoximine	2013

Other Studies

101 other study(ies) available for methionine sulfoximine and ammonium hydroxide

Article	Year
Stimulatory effects of ammonia and glutamine on uric acid synthesis in the chicken (Gallus domesticus) treated with methionine sulfoximine. Comparative biochemistry and physiology. B, Comparative biochemistry, 1976, Volume: 53, Issue:3 Topics: Ammonia; Animals; Chickens; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Methionine Sulfoximine; Uric Acid	1976
Inorganic nitrogen assimilation by the photosynthetic bacterium Rhodopseudomonas capsulata. Journal of bacteriology, 1976, Volume: 128, Issue:2 Topics: Adenosine Monophosphate; Alanine; Amino Acid Oxidoreductases; Ammonia; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Kinetics; Methionine Sulfoximine; Nitrogen; Rhodopseudomonas	1976
Glutaminase-gamma-glutamyltransferase: subcellular localization and ammonia production in acidosis. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 159, Issue:2 Topics: Acidosis; Ammonia; Animals; Cytosol; gamma-Glutamyltransferase; Glutaminase; Glutamine; Kidney; Male; Methionine Sulfoximine; Mitochondria; Perfusion; Rats; Solubility; Subcellular Fractions	1978
The metabolic fate of 13N-labeled ammonia in rat brain. The Journal of biological chemistry, 1979, Jun-25, Volume: 254, Issue:12 Topics: Ammonia; Animals; Biological Transport; Blood-Brain Barrier; Brain; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Male; Methionine Sulfoximine; Nitrogen Isotopes; Rats	1979
Effects of L-methionine-DL-sulfoximine and beta-N-oxalyl-L-alpha, beta-diaminopropionic acid on nitrogenase biosynthesis and activity in Rhodopseudomonas capsulata. Biochemical and biophysical research communications, 1979, Jul-27, Volume: 89, Issue:2 Topics: Amino Acids, Diamino; Ammonia; Biological Transport; Enzyme Repression; Glutamate-Ammonia Ligase; Kinetics; Methionine Sulfoximine; Nitrogenase; Rhodopseudomonas; Structure-Activity Relationship	1979
Molybdenum independence of nitrogenase component synthesis in the non-heterocystous cyanobacterium Plectonema. Journal of bacteriology, 1978, Volume: 134, Issue:2 Topics: Ammonia; Cyanobacteria; Enzyme Activation; Enzyme Induction; Methionine Sulfoximine; Molybdenum; Nitrates; Nitrogenase; Oxygen; Plant Proteins	1978
Transient change in the ATP pool of Anabaena cylindrica associated with ammonia assimilation. Archives of microbiology, 1978, Apr-27, Volume: 117, Issue:1 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonia; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyanobacteria; Darkness; Light; Methionine Sulfoximine	1978
Effects of L-methionine-DL-sulphoximine on the assimilation of newly fixed NH3, acetylene reduction and heterocyst production in Anabaena cylindrica. Biochemical and biophysical research communications, 1975, Aug-04, Volume: 65, Issue:3 Topics: Acetylene; Amino Acids; Ammonia; Cyanobacteria; Enzyme Activation; Enzyme Induction; Glutamate Synthase; Glutamate-Ammonia Ligase; Methionine Sulfoximine; Nitrogenase; Structure-Activity Relationship; Time Factors	1975
Ammoniagenesis: d-glutamyltransferase as a source of ammonia in the rat kidney. Canadian journal of biochemistry, 1975, Volume: 53, Issue:8 Topics: Ammonia; Animals; Biological Transport; gamma-Glutamyltransferase; Glutamine; Kidney; Male; Methionine Sulfoximine; Perfusion; Rats	1975
Glutamine as a feedback inhibitor of the Rhodopseudomonas sphaeroides nitrogenase system. Journal of bacteriology, 1979, Volume: 139, Issue:3 Topics: Ammonia; Feedback; Glutamine; Kinetics; Methionine Sulfoximine; Nitrogenase; Rhodobacter sphaeroides	1979
Pathways of assimilation of [13N]N2 and 13NH4+ by cyanobacteria with and without heterocysts. Journal of bacteriology, 1978, Volume: 134, Issue:1 Topics: Alanine; Ammonia; Citrulline; Cyanobacteria; Glutamates; Glutamine; Methionine Sulfoximine; Nitrogen Fixation; Species Specificity	1978
Metabolism of amino acids and ammonia in rat brain cortex slices in vitro: a possible role of ammonia in brain function. Journal of neurochemistry, 1975, Volume: 25, Issue:3 Topics: Age Factors; Amino Acids; Aminooxyacetic Acid; Ammonia; Amobarbital; Animals; Cerebral Cortex; Dinitrophenols; Female; Fluoroacetates; Glucose; Glutamates; Glutamine; In Vitro Techniques; Male; Malonates; Methionine Sulfoximine; Ouabain; Oxygen Consumption; Proteins; Rats; Synaptosomes	1975
Interaction between ribulose 1,5-bisphosphate carboxylase/oxygenase activity and the ammonia assimilatory system of Rhodobacter sphaeroides. Journal of bacteriology, 1992, Volume: 174, Issue:11 Topics: Ammonia; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Glutamate-Ammonia Ligase; Isoenzymes; Methionine Sulfoximine; Mutation; Protein Processing, Post-Translational; Pyruvates; Pyruvic Acid; Rhodobacter sphaeroides; Ribulose-Bisphosphate Carboxylase	1992
The effect of various culture conditions on the levels of ammonia assimilatory enzymes of Corynebacterium callunae. Archives of microbiology, 1992, Volume: 158, Issue:1 Topics: Ammonia; Corynebacterium; Culture Media; Fumarates; Glucose; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Kinetics; Malates; Methionine Sulfoximine	1992
Restoration of cerebrovascular CO2 responsivity by glutamine synthesis inhibition in hyperammonemic rats. Circulation research, 1992, Volume: 71, Issue:5 Topics: Ammonia; Animals; Carbon Dioxide; Cerebrovascular Circulation; Glutamine; Hypercapnia; Hypocapnia; Male; Methionine Sulfoximine; Rats; Rats, Wistar	1992
A 15N-NMR study of isolated brain in portacaval-shunted rats after acute hyperammonemia. Biochimica et biophysica acta, 1991, Jun-05, Volume: 1096, Issue:4 Topics: Ammonia; Animals; Brain; Glutamate-Ammonia Ligase; Magnetic Resonance Spectroscopy; Male; Methionine Sulfoximine; Perchlorates; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains	1991
Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats. The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 2 Topics: Acetates; Acetic Acid; Ammonia; Animals; Blood Pressure; Brain Edema; Carbon Dioxide; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hemoglobins; Hydrogen-Ion Concentration; Male; Methionine Sulfoximine; Osmolar Concentration; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Reference Values	1991
Methionine sulfoximine intensifies cancer anorexia. Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:1 Topics: Ammonia; Animals; Anorexia; Biogenic Monoamines; Brain Chemistry; Male; Methionine Sulfoximine; Methylcholanthrene; Neoplasms, Experimental; Neurotransmitter Agents; Rats; Rats, Inbred F344; Sarcoma, Experimental	1991
Hyperammonaemia does not impair brain function in the absence of net glutamine synthesis. The Biochemical journal, 1991, Aug-01, Volume: 277 ( Pt 3) Topics: Amino Acids; Ammonia; Animals; Biological Transport; Brain; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Glutamine; Male; Methionine Sulfoximine; Phosphates; Rats; Time Factors; Tryptophan	1991
Photorespiratory ammonia assimilation in the leaves of barley, sorghum and Moricandia arvensis. Indian journal of biochemistry & biophysics, 1990, Volume: 27, Issue:3 Topics: Amino Acids; Ammonia; Glutamate-Ammonia Ligase; Hordeum; Methionine Sulfoximine; Plants	1990
Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation. Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:2 Topics: Acute Disease; Ammonia; Animals; Brain; Brain Diseases; Electroencephalography; Glutamates; Glutamic Acid; Ischemia; Lactates; Lactic Acid; Liver Circulation; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Methionine Sulfoximine; Protons; Rats; Rats, Inbred Strains; Urease	1990
A 15N-n.m.r. study of cerebral, hepatic and renal nitrogen metabolism in hyperammonaemic rats. The Biochemical journal, 1990, Sep-01, Volume: 270, Issue:2 Topics: Adenosine Triphosphate; Alanine; Ammonia; Animals; Brain; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Inactivation, Metabolic; Kidney; Liver; Magnetic Resonance Spectroscopy; Male; Methionine Sulfoximine; Nitrogen; Nitrogen Isotopes; Phosphocreatine; Rats; Rats, Inbred Strains; Urea	1990
Glutamine synthetase inhibition prevents cerebral oedema during hyperammonemia. Acta neurochirurgica. Supplementum, 1990, Volume: 51 Topics: Acetates; Acetic Acid; Ammonia; Animals; Brain Edema; Cerebral Cortex; Glutamate-Ammonia Ligase; Glutamine; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Specific Gravity	1990
Regulation of nitrite uptake and nitrite reductase expression in Chlamydomonas reinhardtii. Biochimica et biophysica acta, 1991, May-24, Volume: 1074, Issue:1 Topics: Ammonia; Chlamydomonas; Cycloheximide; Kinetics; Methionine Sulfoximine; Nitrite Reductases; Nitrites	1991
Effect of methionine sulfoximine on pyruvate dehydrogenase, citric acid cycle enzymes and aminotransferases in the subcellular fractions isolated from rat cerebral cortex. Neuroscience letters, 1990, Jan-22, Volume: 108, Issue:3 Topics: Ammonia; Animals; Cerebral Cortex; Citric Acid Cycle; Convulsants; Methionine Sulfoximine; Mitochondria; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Subcellular Fractions; Transaminases	1990
Effects of three pesticides on MSX-induced ammonia photoproduction by the cyanobacterium Nostoc linckia. Ecotoxicology and environmental safety, 1989, Volume: 18, Issue:2 Topics: 2,4-Dichlorophenoxyacetic Acid; Aldrin; Ammonia; Aniline Compounds; Cyanobacteria; Light; Methionine Sulfoximine; Nitrogenase; Pesticides	1989
Astrocytic pathology of methionine sulfoximine-induced encephalopathy. Acta neuropathologica, 1989, Volume: 77, Issue:4 Topics: Ammonia; Animals; Astrocytes; Brain Diseases; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamates; Methionine Sulfoximine; Rats; Rats, Inbred Strains	1989
Ammonia causes a drop in intracellular pH in metabolizing cortical brain slices. A [31P]- and [1H]nuclear magnetic resonance study. Neuroscience, 1989, Volume: 33, Issue:1 Topics: Acid-Base Equilibrium; Ammonia; Animals; Brain Chemistry; Cerebral Cortex; Energy Metabolism; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Magnetic Resonance Spectroscopy; Methionine Sulfoximine	1989
Incorporation of intraportally infused [15N]ammonia into urinary uric acid in cockerels pretreated with methionine sulfoximine. British poultry science, 1989, Volume: 30, Issue:4 Topics: Ammonia; Animals; Chickens; Glutamate-Ammonia Ligase; Glutamine; Infusions, Intravenous; Kidney; Liver; Male; Methionine Sulfoximine; Portal Vein; Uric Acid	1989
Role of metabolism in the chemotactic response of Rhodobacter sphaeroides to ammonia. Journal of bacteriology, 1989, Volume: 171, Issue:5 Topics: Ammonia; Chemotaxis; Methionine Sulfoximine; Propionates; Rhodobacter sphaeroides	1989
Studies of the mechanism of glutamine synthetase utilizing pH-dependent behavior in catalysis and binding. The Journal of biological chemistry, 1987, Mar-05, Volume: 262, Issue:7 Topics: Adenosine Triphosphate; Amino Acids; Ammonia; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Homocysteine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Lysine; Methionine Sulfoximine; Protons; Spectrometry, Fluorescence; Substrate Specificity; Sulfonamides	1987
Amino acid concentrations in Rhodospirillum rubrum during expression and switch-off of nitrogenase activity. Journal of bacteriology, 1987, Volume: 169, Issue:7 Topics: Amino Acids; Ammonia; Azaserine; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Light; Methionine Sulfoximine; Methylphenazonium Methosulfate; Nitrogen; Nitrogenase; Rhodospirillum	1987
Characterization of the glutamyl-tRNA(Gln)-to-glutaminyl-tRNA(Gln) amidotransferase reaction of Bacillus subtilis. Journal of bacteriology, 1988, Volume: 170, Issue:2 Topics: Ammonia; Asparagine; Bacillus subtilis; Diazooxonorleucine; Glutamate-Ammonia Ligase; Glutamine; Hot Temperature; Methionine Sulfoximine; Mutation; Nitrogenous Group Transferases; RNA, Transfer, Amino Acyl; RNA, Transfer, Gln; Transferases	1988
Effects of varying doses of methionine sulfoximine on liver glutamine synthetase activity and time courses of blood and urinary nitrogenous compounds in the chicken (Gallus domesticus). Comparative biochemistry and physiology. B, Comparative biochemistry, 1988, Volume: 91, Issue:4 Topics: Ammonia; Animals; Chickens; Dose-Response Relationship, Drug; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver; Male; Methionine Sulfoximine; Nitrogen; Uric Acid	1988
Evidence for direct repression of nitrogenase by ammonia in the cyanobacterium Anabaena cylindrica. Biochemical and biophysical research communications, 1986, Jan-29, Volume: 134, Issue:2 Topics: Ammonia; Cyanobacteria; Enzyme Repression; Methionine Sulfoximine; Nitrogenase; Urea	1986
Effect of nitrogenous compounds on nitrogenase gene expression in anaerobic cultures of Anabaena variabilis. Journal of bacteriology, 1988, Volume: 170, Issue:2 Topics: Ammonia; Anaerobiosis; Carbamyl Phosphate; Cyanobacteria; Gene Expression Regulation; Genes, Bacterial; Glutamates; Glutamine; Methionine Sulfoximine; Nitrates; Nitrogen; Nitrogen Fixation; Nitrogenase; Nucleic Acid Hybridization; RNA, Messenger; Transcription, Genetic	1988
Inhibition of nitrate utilization by amino acids in intact Anacystis nidulans cells. Archives of microbiology, 1985, Volume: 142, Issue:1 Topics: Amino Acids; Ammonia; Cyanobacteria; Glutamate Synthase; Methionine Sulfoximine; Nitrates	1985
Methionine sulfoximine prevents the accumulation of large neutral amino acids in brain of portacaval-shunted rats. Journal of neurochemistry, 1985, Volume: 44, Issue:3 Topics: Amino Acids; Ammonia; Animals; Brain; Male; Methionine Sulfoximine; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains	1985
Effect of hyperammonemia and methionine sulfoximine on the kinetic parameters of blood-brain transport of leucine and phenylalanine. Journal of neurochemistry, 1985, Volume: 45, Issue:1 Topics: Ammonia; Animals; Biological Transport; Blood-Brain Barrier; Brain; Capillaries; Glutamine; Kinetics; Leucine; Male; Methionine Sulfoximine; Microscopy, Electron; Phenylalanine; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains	1985
Glutamine synthesis in the perfused rat kidney and in isolated rat cortical tubules: regulation by pH. Clinical science (London, England : 1979), 1985, Volume: 69, Issue:6 Topics: Ammonia; Animals; Gluconeogenesis; Glucose; Glutamates; Glutamine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Tubules; Kinetics; Male; Methionine Sulfoximine; Perfusion; Rats; Rats, Inbred Strains	1985
Studies on glutamine synthetase from Escherichia coli. Formation of pyrrolidone carboxylate and inhibition by methionine sulfoximine. The Journal of biological chemistry, 1973, Jun-10, Volume: 248, Issue:11 Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Brain; Escherichia coli; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Magnesium; Manganese; Methionine Sulfoximine; Protein Binding; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Sheep; Species Specificity; Stereoisomerism	1973
Effect of methionine sulfoximine on glutamine synthetase activity and blood metabolite levels in the chicken (Gallus domesticus). Comparative biochemistry and physiology. B, Comparative biochemistry, 1974, Dec-15, Volume: 49, Issue:4 Topics: Ammonia; Animals; Brain; Chickens; Glutamate-Ammonia Ligase; Glutamine; Heart; Intestine, Small; Kidney; Liver; Male; Methionine Sulfoximine; Myocardium; Organ Specificity; Spectrophotometry, Ultraviolet; Uric Acid	1974
Studies on the mechanism of inhibition of glutamine synthetase by methionine sulfoximine. Biochemistry, 1969, Volume: 8, Issue:3 Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonia; Animals; Binding Sites; Brain; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Drug Stability; Electrophoresis; Glutamates; Glutamine; Hydroxylamines; Kinetics; Ligases; Magnesium; Manganese; Methionine; Methionine Sulfoximine; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Protein Binding; Sheep; Sulfones	1969
Sources of nitrogen as rate-limiting factors for purine biosynthesis de novo in Ehrlich ascites tumor cells. Biochimica et biophysica acta, 1969, Feb-18, Volume: 177, Issue:1 Topics: Adenine; Ammonia; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Diphosphates; Drug Synergism; Glutamine; Glycine; Hypoxanthines; Kinetics; Ligases; Methionine Sulfoximine; Nitrogen; Nucleotides; Pentosephosphates; Purines; Transferases	1969
A spectrophotometric method for the simultaneous measurement of L-glutamine and L-asparagine in biological materials. Analytical biochemistry, 1971, Volume: 40, Issue:2 Topics: Aminohydrolases; Ammonia; Animals; Arginine; Asparagine; Brain; Escherichia coli; Evaluation Studies as Topic; Glutamate Dehydrogenase; Glutamine; Hot Temperature; Humans; Ketoglutaric Acids; Liver; Methionine Sulfoximine; Methods; Mice; NAD; Peptide Hydrolases; Spectrophotometry; Time Factors; Trichloroacetic Acid	1971
Control of glutamine synthesis in rat liver. The Biochemical journal, 1971, Volume: 124, Issue:3 Topics: Alanine; Amino Acids; Ammonia; Animals; Brain; Cyanides; Female; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hydroxylysine; In Vitro Techniques; Liver; Methionine Sulfoximine; Perfusion; Proline; Rats; Starvation	1971
The effect of acute ammonia intoxication upon the brain energy state in rats pretreated with L-methionine D-L-sulphoximine. Scandinavian journal of clinical and laboratory investigation, 1973, Volume: 31, Issue:3 Topics: Acid-Base Equilibrium; Ammonia; Animals; Bicarbonates; Brain Chemistry; Brain Stem; Carbon Dioxide; Depression, Chemical; Energy Metabolism; Frontal Lobe; Glucose; Glutamates; Ketoglutarate Dehydrogenase Complex; Lactates; Male; Methionine Sulfoximine; Phosphates; Poisoning; Pyruvates; Rats	1973
Glutamine synthetase and plasma glutamine in augmented ammoniagenesis in acidosis. The American journal of physiology, 1970, Volume: 218, Issue:6 Topics: Acid-Base Equilibrium; Acidosis; Ammonia; Animals; Glutamine; Hydrogen-Ion Concentration; Ligases; Liver; Male; Methionine Sulfoximine; Rats; Transferases	1970
Glycogen, ammonia and related metabolities in the brain during seizures evoked by methionine sulphoximine. Journal of neurochemistry, 1969, Volume: 16, Issue:2 Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Cerebellum; Cerebral Cortex; Glucose; Glutamates; Glycogen; Lactates; Male; Methionine Sulfoximine; Methods; Phosphocreatine; Rats; Seizures; Time Factors	1969
The influence of x-radiation, methioninesulphoximine, burns, and cytostatic agent TS 160 (Spofa) on the urinary excretion of inorganic phosphates and ammonia and on the level of adenine nucleotides in blood and liver of rats. Neoplasma, 1965, Volume: 12, Issue:6 Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonia; Animals; Blood; Burns; Liver; Methionine; Methionine Sulfoximine; Nitrogen Mustard Compounds; Phosphates; Radiation Effects; Rats; Urine	1965
Evidence for ammonia as an inhibitor of heterocyst and nitrogenase formation in the cyanobacterium Anabaena cycadeae. Biochemical and biophysical research communications, 1983, Feb-28, Volume: 111, Issue:1 Topics: Ammonia; Cyanobacteria; Glutamate-Ammonia Ligase; Methionine Sulfoximine; Mutation; Nitrogenase	1983
L-methionine-SR-sulfoximine as a probe for the role of glutamine synthetase in nitrogenase switch-off by ammonia and glutamine in Rhodopseudomonas palustris. Archives of microbiology, 1983, Volume: 134, Issue:1 Topics: Ammonia; Glutamate-Ammonia Ligase; Glutamine; Methionine Sulfoximine; Nitrogenase; Rhodopseudomonas	1983
Renal recovery from metabolic acidosis in the rat: no role for glutamine synthetase. Renal physiology, 1984, Volume: 7, Issue:1 Topics: Acidosis; Alkalosis; Ammonia; Animals; Bicarbonates; Glutamate-Ammonia Ligase; Glutamine; Kidney; Methionine Sulfoximine; Mitochondria; Rats; Rats, Inbred Strains; Time Factors	1984
Glutamine-dependent synthesis of citrulline by isolated hepatic mitochondria from Squalus acanthias. The Journal of biological chemistry, 1984, Jan-10, Volume: 259, Issue:1 Topics: Ammonia; Ammonium Chloride; Animals; Citrulline; Dogfish; Glutamates; Glutamic Acid; Glutamine; Isoxazoles; Methionine Sulfoximine; Mitochondria, Liver	1984
Suppression of the enzymes of glutamate metabolism in cortical synaptosomes in methionine sulfoximine toxicity. Life sciences, 1984, Jul-09, Volume: 35, Issue:2 Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Cerebral Cortex; Female; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Synaptosomes	1984
Uptake of methionine sulfoximine by some N2 fixing bacteria, and its effect on ammonium transport. FEBS letters, 1983, Nov-28, Volume: 164, Issue:1 Topics: Ammonia; Bacteria; Biological Transport; Carbon Radioisotopes; Kinetics; Klebsiella pneumoniae; Methionine Sulfoximine; Nitrogen Fixation; Rhodobacter sphaeroides; Rhodospirillum rubrum; Species Specificity	1983
In vitro correlation of glutamine and glutamate renal ammoniagenesis during adaptation. Renal physiology, 1984, Volume: 7, Issue:5 Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Ammonia; Animals; Glutamates; Glutamine; In Vitro Techniques; Kidney; Male; Methionine Sulfoximine; Rats	1984
Kinetic characterization of 13NH3 and [13N]glutamine metabolism in rabbit heart. The American journal of physiology, 1984, Volume: 246, Issue:2 Pt 2 Topics: Ammonia; Animals; Chromatography, High Pressure Liquid; Glutamine; Kinetics; Male; Methionine Sulfoximine; Myocardium; Nitrogen Radioisotopes; Rabbits	1984
Methionine sulfoximine prevents the accumulation of large neutral amino acids in brain of hyperammonemic rats. The Journal of surgical research, 1984, Volume: 36, Issue:4 Topics: Amino Acids; Ammonia; Animals; Biological Transport; Blood-Brain Barrier; Brain; Glutamine; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains	1984
Inhibition of nitrogenase activity by NH+4 in Rhodospirillum rubrum. Journal of bacteriology, 1981, Volume: 145, Issue:2 Topics: Ammonia; Hydrogen; Methionine Sulfoximine; Nitrogenase; Rhodospirillum rubrum; Time Factors	1981
Ammonia and methionine sulfoximine intoxication. Brain research, 1982, Jun-24, Volume: 242, Issue:2 Topics: Acetates; Action Potentials; Ammonia; Animals; Brain; Cats; Cerebral Cortex; Evoked Potentials; Methionine Sulfoximine; Pyramidal Tracts	1982
N-13 ammonia as an indicator of myocardial blood flow. Circulation, 1981, Volume: 63, Issue:6 Topics: Ammonia; Animals; Blood Glucose; Blood Pressure; Coronary Circulation; Dogs; Heart Rate; Hydrogen-Ion Concentration; Isoproterenol; Methionine Sulfoximine; Myocardium; Nitrogen Radioisotopes; Propranolol; Regional Blood Flow; Time Factors	1981
The effects of alpha-methylglutamate on ammonium excretion and renal ammonia production in rats. Toxicology and applied pharmacology, 1980, Volume: 54, Issue:3 Topics: Ammonia; Animals; Glutamates; Glutamine; Kidney; Male; Methionine Sulfoximine; Mitochondria; Rats	1980
Astrocyte swelling in liver failure: role of glutamine and benzodiazepines. Acta neurochirurgica. Supplementum, 1994, Volume: 60 Topics: Ammonia; Animals; Animals, Newborn; Astrocytes; Brain Edema; Cells, Cultured; Cerebral Cortex; Chlorides; GABA-A Receptor Antagonists; Glutamate-Ammonia Ligase; Glutamine; Hepatic Encephalopathy; Inositol; Ion Channels; Isoquinolines; Methionine Sulfoximine; Potassium; Rats; Receptors, GABA-A; Water-Electrolyte Balance	1994
Glycerol and lactate induce reciprocal changes in glucose formation and glutamine production in isolated rabbit kidney-cortex tubules incubated with aspartate. Archives of biochemistry and biophysics, 1995, Aug-20, Volume: 321, Issue:2 Topics: Amino Acids; Ammonia; Animals; Aspartic Acid; Gluconeogenesis; Glucose; Glutamine; Glycerol; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Lactates; Lactic Acid; Methionine Sulfoximine; Models, Biological; Rabbits	1995
Investigation of NS0 cell metabolic behavior in monoclonal antibody producing clones. Annals of the New York Academy of Sciences, 1994, Nov-30, Volume: 745 Topics: Ammonia; Animals; Antibodies, Monoclonal; Cell Survival; Culture Media; Culture Techniques; Energy Metabolism; Gene Expression Regulation; Genetic Vectors; Glucose; Glutamate-Ammonia Ligase; Lactates; Lactic Acid; Methionine Sulfoximine; Mice; Osmolar Concentration; Plasmacytoma; Recombinant Fusion Proteins; Tumor Cells, Cultured	1994
Effects of methionine sulphoximine treatment on renal amino acid and ammonia metabolism in rats. Pflugers Archiv : European journal of physiology, 1994, Volume: 427, Issue:5-6 Topics: Amino Acids; Ammonia; Animals; Body Weight; Eating; Glutamine; Kidney; Male; Methionine Sulfoximine; Rats; Rats, Wistar; Renal Circulation; Renal Plasma Flow	1994
Interaction between the glutamine cycle and the uptake of large neutral amino acids in astrocytes. Journal of neurochemistry, 1993, Volume: 60, Issue:5 Topics: Amino Acids; Ammonia; Animals; Astrocytes; Glutamates; Glutamic Acid; Glutamine; Kynurenine; Methionine Sulfoximine; Mice; Phenylalanine	1993
Enhanced endogenous ornithine concentrations protect against tonic seizures and coma in acute ammonia intoxication. Pharmacology & toxicology, 1993, Volume: 72, Issue:2 Topics: 3-Mercaptopropionic Acid; Ammonia; Animals; Brain Chemistry; Coma; Dialysis; Dizocilpine Maleate; Electroshock; Epilepsy, Generalized; Female; Glutamate-Ammonia Ligase; Methionine Sulfoximine; Mice; N-Methylaspartate; Ornithine; Ornithine-Oxo-Acid Transaminase; Pentylenetetrazole; Postural Balance; Putrescine; Strychnine	1993
Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis. Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:6 Topics: Ammonia; Animals; Blood Pressure; Body Water; Brain Edema; Cerebral Cortex; Dose-Response Relationship, Drug; Glutamates; Glutamine; Intracranial Pressure; Male; Methionine Sulfoximine; Portacaval Shunt, Surgical; Pseudotumor Cerebri; Rats; Rats, Sprague-Dawley	1994
Effects of decreased glutamine supply on gut and liver metabolism in vivo in rats. Clinical science (London, England : 1979), 1993, Volume: 85, Issue:4 Topics: Amino Acids; Ammonia; Animals; Glutamine; Intestinal Mucosa; Intestines; Liver; Male; Methionine Sulfoximine; Rats	1993
Impaired pial arteriolar reactivity to hypercapnia during hyperammonemia depends on glutamine synthesis. Stroke, 1996, Volume: 27, Issue:4 Topics: Acetates; Acetic Acid; Ammonia; Animals; Arterioles; Astrocytes; Blood Pressure; Buthionine Sulfoximine; Cerebrovascular Circulation; Enzyme Inhibitors; Glutamine; Hypercapnia; Infusions, Intravenous; Male; Methionine Sulfoximine; Pia Mater; Rats; Rats, Wistar; Reference Values; Regional Blood Flow	1996
Severity of hyperammonemic encephalopathy correlates with brain ammonia level and saturation of glutamine synthetase in vivo. Journal of neurochemistry, 1996, Volume: 67, Issue:4 Topics: Ammonia; Animals; Brain; Glutamate-Ammonia Ligase; Glutamine; Hepatic Encephalopathy; Kinetics; Male; Methionine Sulfoximine; Motor Activity; Posture; Rats; Rats, Wistar; Reflex; Time Factors	1996
Methionine sulfoximine, a glutamine synthetase inhibitor, attenuates increased extracellular potassium activity during acute hyperammonemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:1 Topics: Ammonia; Analysis of Variance; Animals; Glutamate-Ammonia Ligase; Male; Methionine Sulfoximine; Potassium; Rats; Rats, Wistar	1997
Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat. Neuroscience, 1996, Volume: 71, Issue:2 Topics: Ammonia; Animals; Astrocytes; Body Water; Buthionine Sulfoximine; Capillaries; Cell Nucleus; Cell Size; Endoplasmic Reticulum; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Male; Methionine Sulfoximine; Mitochondria; Rats; Rats, Wistar	1996
Effect of the glutamine synthetase inhibitor, methionine sulfoximine, on the growth and differentiation of Dictyostelium discoideum. FEMS microbiology letters, 1997, Jun-15, Volume: 151, Issue:2 Topics: Ammonia; Animals; Dictyostelium; Glutamate-Ammonia Ligase; Methionine Sulfoximine	1997
Preserved hypocapnic pial arteriolar constriction during hyperammonemia by glutamine synthetase inhibition. The American journal of physiology, 1999, Volume: 276, Issue:2 Topics: Acetates; Ammonia; Animals; Arterioles; Buthionine Sulfoximine; Cerebrovascular Circulation; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Hypocapnia; Male; Methionine Sulfoximine; Pia Mater; Rats; Rats, Wistar; Vascular Resistance; Vasoconstriction	1999
Effect of ammonia and methionine sulfoximine on myo-inositol transport in cultured astrocytes. Neurochemical research, 1999, Volume: 24, Issue:1 Topics: Ammonia; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cell Size; Cells, Cultured; Cerebral Cortex; Inositol; Kinetics; Methionine Sulfoximine; Rats; Time Factors	1999
Analogue-resistant mutants of Azotobacter chroococcum derepressed for nitrogenase activity and early ammonia excretion having potential as inoculants for cereal crops. Indian journal of experimental biology, 2000, Volume: 38, Issue:4 Topics: Alanine; Ammonia; Azotobacter; Drug Resistance, Microbial; Edible Grain; Methionine Sulfoximine; Methylamines; Mutation; Nitrogen Fixation; Nitrogenase	2000
Effect of acute exposure to ammonia on glutamate transport in glial cells isolated from the salamander retina. Journal of neurophysiology, 2001, Volume: 86, Issue:2 Topics: Amino Acid Transport System X-AG; Ammonia; Animals; Anions; Aspartic Acid; ATP-Binding Cassette Transporters; Cell Separation; Glutamate-Ammonia Ligase; Glutamic Acid; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Potentials; Methionine Sulfoximine; Neuroglia; Patch-Clamp Techniques; Potassium; Quaternary Ammonium Compounds; Retina; Sodium; Urodela	2001
EFFECTS OF METHIONINE SULFOXIMINE ON LEVELS OF FREE AMINO ACIDS AND RELATED SUBSTANCES IN BRAIN. Biochemical pharmacology, 1964, Volume: 13 Topics: Amino Acids; Amino Alcohols; Aminobutyrates; Ammonia; Animals; Brain; Chromatography; Dogs; Lactates; Methionine; Methionine Sulfoximine; Nerve Tissue Proteins; Neurochemistry; Pharmacology; Research	1964
EFFECT OF AN INHIBITOR OF GLUTAMINE SYNTHESIS (METHIONINE SULFOXIMINE) ON AMMONIA TOXICITY AND METABOLISM. The Journal of laboratory and clinical medicine, 1964, Volume: 64 Topics: Ammonia; Ammonium Chloride; Brain Chemistry; Enzyme Inhibitors; Glutamine; Ligases; Metabolism; Methionine; Methionine Sulfoximine; Mice; Pharmacology; Research; Toxicology	1964
Role of ammonia in reversal of glutamate-mediated Müller cell swelling in the rat retina. Glia, 2004, Volume: 48, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Ammonia; Animals; Cell Death; Cell Size; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hypothermia; Methionine Sulfoximine; Neurons; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases; Tissue Fixation	2004
Glutamine-dependent inhibition of pial arteriolar dilation to acetylcholine with and without hyperammonemia in the rat. American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:6 Topics: Acetylcholine; Ammonia; Animals; Arterioles; Blood Gas Analysis; Blood Pressure; Cerebrovascular Circulation; Endothelium, Vascular; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamine; Intracranial Pressure; Male; Methionine Sulfoximine; Nitroprusside; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents	2005
Chronic and acute ammonia toxicity in mudskippers, Periophthalmodon schlosseri and Boleophthalmus boddaerti: brain ammonia and glutamine contents, and effects of methionine sulfoximine and MK801. The Journal of experimental biology, 2005, Volume: 208, Issue:Pt 10 Topics: Acetates; Ammonia; Animals; Brain; Dizocilpine Maleate; Glutamate-Ammonia Ligase; Glutamine; Lethal Dose 50; Malaysia; Methionine Sulfoximine; Perciformes; Receptors, N-Methyl-D-Aspartate; Species Specificity	2005
Ammonia affects brain nitrogen metabolism but not hydration status in the Gulf toadfish (Opsanus beta). Aquatic toxicology (Amsterdam, Netherlands), 2005, Aug-15, Volume: 74, Issue:1 Topics: Ammonia; Animals; Batrachoidiformes; Body Water; Brain; Glutamate-Ammonia Ligase; Glutamine; Intracranial Pressure; Magnetic Resonance Imaging; Methionine Sulfoximine; Nitrogen; Osmolar Concentration; Seawater	2005
Ammonia toxicity and tolerance in the brain of the African sharptooth catfish, Clarias gariepinus. Aquatic toxicology (Amsterdam, Netherlands), 2007, May-15, Volume: 82, Issue:3 Topics: Alanine Transaminase; Amino Acids; Ammonia; Animals; Brain; Catfishes; Dizocilpine Maleate; Environmental Exposure; Female; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Injections, Intraperitoneal; Male; Methionine Sulfoximine; Neuroprotective Agents; Survival Analysis; Time Factors	2007
Effect of glutamine synthesis inhibition with methionine sulfoximine on the nitric oxide-cyclic GMP pathway in the rat striatum treated acutely with ammonia: a microdialysis study. Neurochemical research, 2008, Volume: 33, Issue:2 Topics: Ammonia; Animals; Corpus Striatum; Glutamine; Guanosine Monophosphate; Male; Methionine Sulfoximine; Microdialysis; Nitric Oxide; Rats; Rats, Sprague-Dawley	2008
Presence of a functional nitrate assimilation pathway in Mycobacterium smegmatis. Microbial pathogenesis, 2008, Volume: 44, Issue:1 Topics: Ammonia; Asparagine; Enzyme Inhibitors; Methionine Sulfoximine; Mycobacterium smegmatis; Nitrates; Nitrogen; Sodium Azide; Sodium Nitrite; Survival Analysis; Time Factors	2008
Mechanisms of and defense against acute ammonia toxicity in the aquatic Chinese soft-shelled turtle, Pelodiscus sinensis. Aquatic toxicology (Amsterdam, Netherlands), 2008, Jan-31, Volume: 86, Issue:2 Topics: Amino Acids; Ammonia; Ammonium Chloride; Animals; Brain; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Liver; Methionine Sulfoximine; Muscles; Turtles; Urea; Water	2008
Altered fatty acid metabolism and composition in cultured astrocytes under hyperammonemic conditions. Journal of neurochemistry, 2009, Volume: 109 Suppl 1 Topics: Ammonia; Animals; Astrocytes; Cells, Cultured; Enzyme Inhibitors; Fatty Acids; Glutamate-Ammonia Ligase; Lipids; Magnetic Resonance Spectroscopy; Methionine Sulfoximine; Mitochondria; Rats; Rats, Wistar	2009
Acute ammonia toxicity and the protective effects of methionine sulfoximine on the swamp eel, Monopterus albus. Journal of experimental zoology. Part A, Ecological genetics and physiology, 2009, Nov-01, Volume: 311, Issue:9 Topics: Acetates; Acute Disease; Alanine Transaminase; Amino Acids; Ammonia; Animals; Brain; Enzyme Inhibitors; Female; Glutamate-Ammonia Ligase; Injections, Intraperitoneal; Liver; Male; Methionine Sulfoximine; Muscle, Skeletal; Smegmamorpha; Urea	2009
In vivo monitoring of extracellular 13N-glutamine derived from blood-borne 13N-ammonia in rat striatum using microdialysis with radio-LC method. Journal of neuroscience methods, 2009, Oct-30, Volume: 184, Issue:1 Topics: Acetates; Ammonia; Animals; Astrocytes; Chromatography, Liquid; Citrates; Corpus Striatum; Extracellular Space; Glutamate-Ammonia Ligase; Glutamine; Male; Methionine Sulfoximine; Microdialysis; Nitrogen Radioisotopes; Radiometry; Rats; Rats, Sprague-Dawley; Time Factors	2009
Inhibition of glutamine synthetase during ammonia exposure in rainbow trout indicates a high reserve capacity to prevent brain ammonia toxicity. The Journal of experimental biology, 2010, Jul-01, Volume: 213, Issue:Pt 13 Topics: Ammonia; Animals; Brain; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamine; Methionine Sulfoximine; Oncorhynchus mykiss	2010
Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons. Neurochemistry international, 2011, Volume: 59, Issue:4 Topics: Alanine; Alanine Transaminase; Ammonia; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Hyperammonemia; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Neurons	2011
Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:8 Topics: Alanine; Amino Acids; Ammonia; Animals; Astrocytes; Brain Chemistry; Chromatography, High Pressure Liquid; Coculture Techniques; Enzyme Inhibitors; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutamate-Ammonia Ligase; Hyperammonemia; Methionine Sulfoximine; Neurons; Rats; Rats, Wistar	2013
Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:3 Topics: Amino Acids; Ammonia; Animals; Brain; Female; Glutamate-Ammonia Ligase; Hepatic Encephalopathy; Kidney; Liver; Methionine Sulfoximine; Organ Specificity; Rats; Rats, Wistar	2014
Assessment of glutamine synthetase activity by [13N]ammonia uptake in living rat brain. Synapse (New York, N.Y.), 2015, Volume: 69, Issue:1 Topics: Ammonia; Animals; Autoradiography; Brain; Cerebrovascular Circulation; Enzyme Inhibitors; Feasibility Studies; gamma-Glutamyltransferase; Glutamate-Ammonia Ligase; Male; Methionine Sulfoximine; Nitrogen Radioisotopes; Oxygen Radioisotopes; Positron-Emission Tomography; Radiopharmaceuticals; Rats, Sprague-Dawley; Tomography, X-Ray Computed; Water	2015
Feeding through your gills and turning a toxicant into a resource: how the dogfish shark scavenges ammonia from its environment. The Journal of experimental biology, 2016, 10-15, Volume: 219, Issue:Pt 20 Topics: Amiloride; Ammonia; Animals; Carbon Radioisotopes; Dogfish; Environment; Gills; Hydrogen-Ion Concentration; Male; Methionine Sulfoximine; Methylamines; Nitrogen; Potassium; Seawater; Urea; Water	2016
Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies. Scientific reports, 2018, 03-29, Volume: 8, Issue:1 Topics: Ammonia; Animals; Antibodies, Monoclonal; CHO Cells; Clone Cells; Cricetulus; Gene Knockout Techniques; Glutamate-Ammonia Ligase; Lactic Acid; Methionine Sulfoximine	2018
Acute ammonia poisoning in dolly varden char (Salvelinus malma) and effect of methionine sulfoximine. Fish & shellfish immunology, 2020, Volume: 101 Topics: Amino Acids; Ammonia; Animals; Blood Chemical Analysis; Gene Expression; Immunity; Methionine Sulfoximine; Protective Agents; Trout	2020