methionine sulfoximine has been researched along with acetaminophen in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 11 (57.89) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franklin, MR; Galinsky, RE; Kimura, RE; Manning, BW | 1 |
| Arancibia, C; Campos, R; Garrido, A; Valenzuela, A | 1 |
| Bray, GP; Tredger, JM; Williams, R | 1 |
| Chong, MG; He, DE; Kelly, JH; Koussayer, T; Shang, TA; Sussman, NL; Whisennand, HH | 1 |
| Corrales, F; Martin-Lomas, M; Mato, JM; Ochoa, P; Pajares, MA; Rivas, C | 1 |
| Bruno, M; Gamache, P; Hinson, JA; Khairallah, E; Klein, NW; Weeks, BS | 1 |
| Corcoran, GB; Wong, BK | 1 |
| Yeung, JH | 1 |
| Bauer, JA; Corcoran, GB; Lau, TW | 1 |
| Fricke, RF; Goon, DJ; Nagasawa, HT; Roberts, JC; Zera, RT | 1 |
| Galinsky, RE | 1 |
| Griffith, KL; Hue, DP; McLean, AE | 1 |
| Drew, R; Miners, JO | 1 |
| Birkett, DJ; Drew, R; Miners, JO | 1 |
| Fujihara, Y; Iguchi, S; Kaneo, Y; Ogawa, K; Tanaka, T | 1 |
| Barr, SG; Harrison, JJ; Racz, WJ; Rafeiro, E | 1 |
| Dalhoff, K; Poulsen, HE | 1 |
| Cargill, I; Howell, S; Lindenthal, J; Sinclair, JF; Sinclair, PR; Taylor, T | 1 |
| Bánhegyi, G; Braun, L; Csala, M; Garzó, T; Mandl, J; Poussu, A | 1 |
19 other study(ies) available for methionine sulfoximine and acetaminophen
| Article | Year |
|---|---|
Changes in conjugative enzyme activity and acetaminophen metabolism in young and senescent male F-344 rats following prolonged exposure to buthionine sulfoximine.
Topics: Acetaminophen; Aging; Animals; Antimetabolites; Buthionine Sulfoximine; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Glutathione; Glutathione Transferase; Liver; Male; Methionine Sulfoximine; Oxidoreductases, O-Demethylating; Rats; Rats, Inbred F344; Sulfotransferases | 1992 |
Acetaminophen does not induce oxidative stress in isolated rat hepatocytes: its probable antioxidant effect is potentiated by the flavonoid silybin.
Topics: Acetaminophen; Animals; Antioxidants; Buthionine Sulfoximine; Drug Synergism; Glutamate-Cysteine Ligase; Glutathione; In Vitro Techniques; Lipid Peroxidation; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Silymarin; Stress, Physiological | 1991 |
S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mortality; S-Adenosylmethionine | 1992 |
An improved model of acetaminophen-induced fulminant hepatic failure in dogs.
Topics: Acetaminophen; Alanine Transaminase; Animals; Biopsy; Blood Glucose; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Dogs; Liver; Liver Diseases; Male; Methemoglobinemia; Methionine Sulfoximine; Pulmonary Edema; Vacuoles | 1992 |
Inhibition of glutathione synthesis in the liver leads to S-adenosyl-L-methionine synthetase reduction.
Topics: Acetaminophen; Animals; Antimetabolites; Buthionine Sulfoximine; Glutathione; Liver; Male; Methionine Adenosyltransferase; Methionine Sulfoximine; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1991 |
Acetaminophen toxicity to cultured rat embryos.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Culture Techniques; Female; Glutathione; Macaca mulatta; Maternal-Fetal Exchange; Methionine Sulfoximine; Pregnancy; Rats; Rats, Inbred Strains; Teratogens | 1990 |
Effects of esterase inhibitors and buthionine sulfoximine on the prevention of acetaminophen hepatotoxicity by N-acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Esterases; Isoflurophate; Lysine; Male; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Nitrophenols; Organophosphorus Compounds; Phenylmethylsulfonyl Fluoride | 1987 |
Effect of sulphydryl drugs on paracetamol-induced hepatotoxicity in mice.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antimetabolites; Blood Proteins; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Sulfhydryl Compounds | 1988 |
Immediate rise in intracellular calcium and glycogen phosphorylase a activities upon acetaminophen covalent binding leading to hepatotoxicity in mice.
Topics: Acetaminophen; Administration, Oral; Animals; Buthionine Sulfoximine; Calcium; Chemical and Drug Induced Liver Injury; Enzyme Activation; Glutathione; Liver Diseases; Male; Methionine Sulfoximine; Mice; Phosphorylase a; Phosphorylases; Protein Binding | 1988 |
Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cysteine; Drug Therapy; Glutathione; Liver; Methionine Sulfoximine; Mice; Prodrugs; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1987 |
Role of glutathione turnover in drug sulfation: differential effects of diethylmaleate and buthionine sulfoximine on the pharmacokinetics of acetaminophen in the rat.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Glutathione; Kidney; Kinetics; Male; Maleates; Metabolic Clearance Rate; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Sulfates | 1986 |
Hepatocytes in primary culture become susceptible to paracetamol injury after depletion of glutathione using DL-buthionine-SR-sulphoximine (BSO).
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cells, Cultured; Glutathione; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains | 1985 |
The effects of buthionine sulphoximine (BSO) on glutathione depletion and xenobiotic biotransformation.
Topics: Acetaminophen; Animals; Biotransformation; Buthionine Sulfoximine; Glutamate-Cysteine Ligase; Glutathione; In Vitro Techniques; Male; Methionine Sulfoximine; Mice; Mice, Inbred C3H | 1984 |
Mechanism of action of paracetamol protective agents in mice in vivo.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Buthionine Sulfoximine; Cysteamine; Cysteine; Glutathione; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H | 1984 |
A protective effect of glutathione-dextran macromolecular conjugates on acetaminophen-induced hepatotoxicity dependent on molecular size.
Topics: Acetaminophen; Animals; Antimetabolites; Aspartate Aminotransferases; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyanogen Bromide; Delayed-Action Preparations; Dextrans; Disease Models, Animal; Drug Delivery Systems; Glutathione; In Vitro Techniques; Injections, Intravenous; Liver; Liver Diseases; Male; Methionine Sulfoximine; Mice; Molecular Weight; Survival Rate | 1994 |
Effects of N-acetylcysteine and dithiothreitol on glutathione and protein thiol replenishment during acetaminophen-induced toxicity in isolated mouse hepatocytes.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Dithiothreitol; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Mice; Sulfhydryl Compounds | 1994 |
Simultaneous measurements of glutathione and activated sulphate (PAPS) synthesis rates and the effects of selective inhibition of glutathione conjugation or sulphation of acetaminophen.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cells, Cultured; Female; Glutathione; Liver; Methionine Sulfoximine; Nitrophenols; Phosphoadenosine Phosphosulfate; Rats; Rats, Wistar; Sulfates; Sulfotransferases | 1993 |
Toxicity of paracetamol in cultured chick hepatocytes treated with methotrexate.
Topics: Acetaminophen; Animals; Benzoflavones; beta-Naphthoflavone; Buthionine Sulfoximine; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; Glutathione; Liver; Methionine Sulfoximine; Methotrexate | 1993 |
Glutathione depletion induces glycogenolysis dependent ascorbate synthesis in isolated murine hepatocytes.
Topics: Acetaminophen; Animals; Ascorbic Acid; Bucladesine; Buthionine Sulfoximine; Cyclic AMP; Diamide; Fructose; Glutathione; Glycogen; Liver; Male; Methionine Sulfoximine; Mice; Sugar Acids; Uridine Diphosphate Glucose; Vitamin K | 1996 |