methionine has been researched along with simvastatin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 12 (70.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bereziat, G; Chambaz, J; Janvier, B; Loriette, C; Mangeney, M; Pepin, D; Ribeiro, A; Thomas, G | 1 |
| Correa-Cerro, LS; Fliesler, SJ; Grinberg, A; Kratz, L; Miller, GF; Munasinghe, JP; Porter, FD; Wassif, CA | 1 |
| Engert, A; Hansen, HP; Sasse, S; Tawadros, S; von Strandmann, EP; von Tresckow, B | 1 |
| Horiuchi, N; Maeda, T | 1 |
| Hirose, K; Ikeda, K; Iwamoto, I; Kagami, S; Kanari, H; Nakajima, H; Owada, T; Saito, Y; Suto, A; Watanabe, N | 1 |
| Carter, EA; Fischman, A; Fukaya, M; Inoue, Y; Kaneki, M; Ming-Yu, Y; Shinozaki, S; Tompkins, R; Yang, W; Yu, YM | 1 |
| Jefferson, LS; Jefferson, SJ; Kimball, SR; Tuckow, AP | 1 |
| Calzetta, L; Capuano, A; Cazzola, M; Matera, MG; Page, CP; Rinaldi, B | 1 |
| Ageberg, M; Drott, K; Jerkeman, M; Lindén, O; Linderoth, J; Rydström, K | 1 |
| Aránguiz, P; Canales, J; Catalán, M; Chiong, M; Copaja, M; Díaz-Araya, G; Lavandero, S; Leyton, L; Olmedo, I; Rodríguez, AE; Venegas, D; Vivar, R | 1 |
| Chakir, J; Ghavami, S; Halayko, AJ; Jacques, E; Laviolette, M; McNeill, KD; Mutawe, MM; Schaafsma, D; Unruh, H | 1 |
| Ablao, KP; Bodmer, R; Dhahbi, JM; Li, R; Mote, P; Ocorr, K; Spindler, SR; Wang, Y; Williams, RT; Yamakawa, A | 1 |
| Awad, AS; El-Dessouki, AM; Galal, MA; Zaki, HF | 1 |
| Kowluru, A; Syeda, KG | 1 |
| Bona, S; Di Naso, FC; Dias, AS; Marroni, CA; Marroni, NP; Moreira, AJ; Picada, JN; Pires, TR; Rodrigues, G; Schemitt, E | 1 |
1 review(s) available for methionine and simvastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
16 other study(ies) available for methionine and simvastatin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of simvastatin on the synthesis and secretion of lipoproteins in relation to the metabolism of cholesterol in cultured hepatocytes.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cholesterol; Cholesterol Esters; Fatty Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins; Liver; Lovastatin; Male; Methionine; Rats; Rats, Inbred Strains; Simvastatin; Triglycerides | 1991 |
Development and characterization of a hypomorphic Smith-Lemli-Opitz syndrome mouse model and efficacy of simvastatin therapy.
Topics: 3T3 Cells; Alleles; Amino Acid Substitution; Animals; Cells, Cultured; Crosses, Genetic; Disease Models, Animal; Embryonic Stem Cells; Female; Magnetic Resonance Spectroscopy; Methionine; Mice; Mice, Inbred C57BL; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-CH Group Donors; Phenotype; Simvastatin; Smith-Lemli-Opitz Syndrome; Threonine | 2006 |
Simvastatin-dependent apoptosis in Hodgkin's lymphoma cells and growth impairment of human Hodgkin's tumors in vivo.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Enzyme Inhibitors; Farnesyltranstransferase; Hodgkin Disease; Humans; K562 Cells; Methionine; Mice; Neoplasm Transplantation; Protein Prenylation; Protein Processing, Post-Translational; Simvastatin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2007 |
Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Benzamides; Cell Differentiation; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoquinolines; Leptin; Methionine; Mevalonic Acid; Mice; Morpholines; Polyisoprenyl Phosphates; Protein Prenylation; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Simvastatin; Sulfonamides; Wortmannin | 2009 |
Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3+ regulatory T cells.
Topics: Animals; Benzamides; Cell Differentiation; Forkhead Transcription Factors; Gene Expression Regulation; Interleukin-17; Interleukin-6; Methionine; Mice; Mice, Inbred BALB C; Mice, Transgenic; Ovalbumin; Peptide Fragments; Prenylation; Receptors, Antigen, T-Cell, alpha-beta; Severe Combined Immunodeficiency; Simvastatin; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2009 |
Farnesyltransferase inhibitor improved survival following endotoxin challenge in mice.
Topics: Animals; Apoptosis; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Farnesyltranstransferase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipopolysaccharides; Liver; Male; MAP Kinase Kinase 4; Methionine; Mice; Mice, Inbred C57BL; Simvastatin; Spleen | 2010 |
Simvastatin represses protein synthesis in the muscle-derived C₂C₁₂ cell line with a concomitant reduction in eukaryotic initiation factor 2B expression.
Topics: Blotting, Western; Cell Line; Cysteine; Eukaryotic Initiation Factor-2B; Guanine Nucleotides; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Methionine; Mevalonic Acid; Muscle Cells; Muscle Proteins; Protein Synthesis Inhibitors; Simvastatin | 2011 |
Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi.
Topics: Alkyl and Aryl Transferases; Amides; Bronchi; Bronchoconstriction; Electric Stimulation; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; In Vitro Techniques; Leucine; Lipopolysaccharides; Male; Methionine; Middle Aged; Naphthalenes; Polyisoprenyl Phosphates; Protein Kinase Inhibitors; Protein Prenylation; Pyridines; ras Proteins; rho GTP-Binding Proteins; rho-Associated Kinases; Sesquiterpenes; Signal Transduction; Simvastatin; Time Factors | 2011 |
Inhibition of geranylgeranylation mediates sensitivity to CHOP-induced cell death of DLBCL cell lines.
Topics: Alkyl and Aryl Transferases; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lymphoma, Large B-Cell, Diffuse; Methionine; Prednisone; Prenylation; Rituximab; Simvastatin; Vincristine | 2011 |
Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts.
Topics: Animals; Apoptosis; Benzamides; Caspases; Cell Survival; Cells, Cultured; Cholesterol; Fibroblasts; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Methionine; Myofibroblasts; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Simvastatin | 2011 |
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts.
Topics: Adult; Airway Remodeling; Alkyl and Aryl Transferases; Asthma; Bronchi; Case-Control Studies; Cells, Cultured; Dose-Response Relationship, Drug; Farnesyltranstransferase; Fibroblasts; Fibronectins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leucine; Methionine; Mevalonic Acid; Polyisoprenyl Phosphates; Sesquiterpenes; Simvastatin; Time Factors; Transforming Growth Factor beta1; Young Adult | 2011 |
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation.
Topics: Aging; Animals; Behavior, Animal; Benzamides; Cardiovascular Diseases; Drosophila melanogaster; Feeding Behavior; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Longevity; Male; Methionine; Mice; Simvastatin; Ubiquinone | 2012 |
Neuroprotective Effects of Simvastatin and Cilostazol in L-Methionine-Induced Vascular Dementia in Rats.
Topics: Animals; Brain; Cilostazol; Dementia, Vascular; Disease Models, Animal; Endothelium, Vascular; Male; Maze Learning; Memory; Methionine; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Simvastatin; Tetrazoles | 2017 |
Inhibition of Prenylation Promotes Caspase 3 Activation, Lamin B Degradation and Loss in Metabolic Cell Viability in Pancreatic β-Cells.
Topics: Animals; Caspase 3; Cell Survival; Cells, Cultured; Farnesyltranstransferase; Glucose; Humans; Insulin-Secreting Cells; Lamin Type B; Male; Methionine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Octoxynol; p38 Mitogen-Activated Protein Kinases; Polyethylene Glycols; Protein Prenylation; Proteolysis; Rats; Rats, Sprague-Dawley; Simvastatin | 2017 |
Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model.
Topics: Animals; Antioxidants; Choline Deficiency; Endoplasmic Reticulum Stress; Glutathione Peroxidase; Inflammation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Simvastatin; Superoxide Dismutase | 2019 |