methionine has been researched along with s-adenosylmethionine in 877 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 395 (45.04) | 18.7374 |
| 1990's | 99 (11.29) | 18.2507 |
| 2000's | 151 (17.22) | 29.6817 |
| 2010's | 146 (16.65) | 24.3611 |
| 2020's | 86 (9.81) | 2.80 |
| Authors | Studies |
|---|---|
| Eustáquio, AS; Moore, BS; Noel, JP; Pojer, F | 1 |
| Baena, RM; Bayés, R; Campoy, C; Goicoechea, A; López, C; Molina-Font, JA; Pedrosa, T; Peinado, JM; Rivero, M | 1 |
| Aponte, A; Balaban, RS; French, S; Harris, RA; Johnson, DT | 1 |
| Caggana, M; Cohen-Pfeffer, JL; Diaz, GA; Kirmse, BM; McGuire, PJ; Morrissey, MA; Salveson, BR; Sunny, S; Wasserstein, MP; Weisfeld-Adams, JD; Yu, C | 1 |
| Chace, DH; De Jesús, VR; Hannon, WH; Lim, TH; Mei, JV | 1 |
| Eisenhofer, G; Julius, U; Peitzsch, M; Reimann, M; Ziemssen, T | 1 |
| Jacobs, A; Jansen Van Vuren, E; Kruger, R; Louw, R; Mels, C; Strauss-Kruger, M | 1 |
| Butt, VS; Poulton, JE | 1 |
| Fukui, S; Nakatani, K; Ohmori, H; Shirakashi, T; Sugimoto, Y; Toraya, T | 1 |
| DiGirolamo, PM; Fujii, K; Huennekens, FM; Jacobsen, DW; Vitols, KS | 1 |
| Cohen, PA; Tallan, HH | 1 |
| Cook, DE; Dang, AQ | 1 |
| Benevenga, NJ; Stipanuk, MH | 1 |
| Grantham, PH; Poirier, LA; Rogers, AE | 1 |
| Callebaut, A; Lambein, F; Van Parijs, R | 1 |
| Montie, DB; Montie, TC | 2 |
| Burton, EG; Metzenberg, RL | 2 |
| Lambowitz, AM; Luck, DJ | 1 |
| Breton, A; Surdin-Kerjan, Y | 1 |
| Arigoni, D | 1 |
| Baldessarini, RJ; Stramentinoli, G | 1 |
| Unger, MW | 1 |
| Choih, SJ; Ferro, AJ; Shapiro, SK | 1 |
| Spencer, M; Thomas, KC | 1 |
| Cherest, H; Surdin-Kerjan, Y | 1 |
| Benesh, FC; Carl, GF | 1 |
| Cronan, JE; Jackson, MB; Reed, R; Taylor, FR | 1 |
| Baldessarini, RJ; Lipinski, JF; Stramentinoli, G | 1 |
| Cohen, SS; Lapi, L; Torget, R | 1 |
| Garrels, JI; Hunter, T | 1 |
| Chrin, LR; Jaffe, JJ | 1 |
| Bates, PC; Grimble, GK; Millward, DJ | 1 |
| Deeprose, RD; Duncan, GS; Harvey, RJ; Wolberg, G; Zimmerman, TP | 1 |
| Ferro, AJ; Hannum, CH; Schlenk, F | 1 |
| Eloranta, TO | 1 |
| Eloranta, TO; Raina, AM | 1 |
| Benevenga, NJ; Mitchell, AD | 1 |
| Andreana, A; Galletti, P; Porcelli, M; Ruggiero, G; Zappia, V | 1 |
| Caboche, M; Mulsant, P | 1 |
| Ordonez, LA; Wurtman, RJ | 4 |
| Akesson, B | 1 |
| Caboche, M; Hatzfeld, J | 1 |
| Benesh, FC; Carl, GF; Hudson, JL | 1 |
| Andreana, A; Cacciapuoti, G; Porcelli, M; Ruggiero, G; Zappia, V | 1 |
| Cherest, H; De Robichon-Szulmajster, H; Surdin-Kerjan, Y | 2 |
| Delk, AS; Rabinowitz, JC | 1 |
| Arnold, HH; Kersten, H; Schmidt, W | 1 |
| Morzycka, E; Raczyńska-Bojanowska, K; Sawnor-Korszyńska, D; Zaborowska, D | 1 |
| Petri, WA; Poirier, LA | 1 |
| Caboche, M | 1 |
| Edwards, CH; Edwards, GA; Freeburne, MM; Jones, EG; Seo, CW; Sherman, L; Stacey, RE; Wade, WD | 1 |
| Carrell, HL; Cornforth, JW; Glusker, JP; Reichard, SA; Talalay, P | 1 |
| Altman, NH; Brada, Z; Bulba, S | 1 |
| Fukui, S; Sugimoto, Y; Toraya, T | 1 |
| Grabski, J; Morzycka, E; Paszewski, A; Raczyńska-Bojanowska, K; Sawnor-Korszyńska, D | 1 |
| Case, GL | 1 |
| Schulman, JD | 1 |
| Holcomb, ER; Shapiro, SK | 1 |
| de Robichon-Szulmajster, H; Surdin-Kerjan, Y | 1 |
| Cherest, H; Colombani, F; de Robichon-Szulmajster, H | 1 |
| Kim, S; Paik, WK | 2 |
| de Robichon-Szulmajster, H; Feldmann, H; Fesneau, C; Fradin, A | 1 |
| Aswad, DW; Koshland, DE | 1 |
| Adler, J; Kort, EN; Larsen, SH; Ordal, GW; Reader, RW; Springer, MS | 1 |
| Baldessarini, RJ | 2 |
| Schatz, RA; Sellinger, OZ | 2 |
| Paulus, H; Wyman, A | 1 |
| Paulus, H; Shelton, E; Wyman, A | 1 |
| Finkelstein, JD; Kyle, WE; Martin, JL; Pick, AM | 1 |
| Beuhring, KU; Shin, YS; Stokstad, EL | 1 |
| Swann, PF | 1 |
| Buehring, YS; Poirier, LA; Stokstad, EL | 1 |
| Nair, CP; Stokstad, EL | 1 |
| Ono, BI; Paszewski, A | 1 |
| Avram, D; Stan, R | 1 |
| Ballinger, MD; Eliasson, R; Harder, J; Pontis, E; Reichard, P | 1 |
| Barbey, R; Henry, D; Surdin-Kerjan, Y; Thomas, D | 1 |
| Poirier, LA; Wainfan, E | 1 |
| Fullerton, FR; Hathcock, JN; Poirier, LA; Reicks, MM; Whittaker, P | 1 |
| Byström, AS; Korch, C; Mountain, HA | 1 |
| Akerman, K; Eloranta, TO; Harvima, RJ; Kajander, EO; Kantola, M; Kärenlampi, SO; Martikainen, H | 1 |
| Dreyfus, H; Ferret, B; Hubsch, A; Massarelli, R | 1 |
| Miller, JW; Selhub, J | 1 |
| Bray, GP; Tredger, JM; Williams, R | 1 |
| Mathur, M; Sachar, RC | 1 |
| Schalinske, KL; Steele, RD | 2 |
| Hyland, K; Smith, I; Surtees, R | 1 |
| Cherest, H; Surdin-Kerjan, Y; Thomas, D | 1 |
| Cabrero, C; Corrales, F; Martin-Duce, A; Mato, JM; Ortiz, P; Pajares, MA | 1 |
| Marchesini, G; Pisi, E | 1 |
| Fell, D; Selhub, J | 1 |
| Kodama, K; Oguchi, K; Tsuji, M | 2 |
| Lyn-Cook, B; Poirier, LA; Zapisek, W | 1 |
| Frey, PA; Moss, ML | 1 |
| Cumaraswamy, A; Henney, H | 1 |
| Hyland, K; Surtees, R | 2 |
| Liteplo, RG | 2 |
| Bottiglieri, T; Chanarin, I; Metz, J; Van der Westhuyzen, J; Vieira-Makings, E | 1 |
| Akerman, KK; Harvima, RJ; Kajander, EO; Kärenlampi, SO; Kauppinen, L; Martikainen, H; Pajula, RL | 1 |
| White, RH | 1 |
| Eloranta, TO; Martikainen, V; Smith, TK | 1 |
| Caldwell, DC; Emerson, CP | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 1 |
| Ellis, M; Frost, P; Judde, JG | 1 |
| Henning, SM; McKee, RW; Swendseid, ME | 1 |
| Arenson, E; Begley, JA; Chu, RC; Hall, CA; Lindenbaum, RH | 1 |
| Cozzolino, P; Daino, L; Feo, F; Frassetto, S; Garcea, R; Pascale, R; Ruggiu, ME; Vannini, MG | 1 |
| Hipwell, SE; Liteplo, RG | 1 |
| Durbin, RK; Scheidel, LM; Stollar, V | 1 |
| LeBel, CP; Schatz, RA | 1 |
| Davidson, BE; Saint Girons, I | 1 |
| Cook, RJ; Horne, DW; Wagner, C | 1 |
| Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Bottiglieri, T; Nunn, JF; Royston, BD | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 4 |
| daCosta, KA; Pomfret, EA; Zeisel, SH; Zola, T | 1 |
| Gharib, A; Greenland, T; Hamidi, J; Khatchadourian, C; Menezo, Y; Sarda, N | 1 |
| Fishlock, RC; Snoswell, AM; Xue, GP | 1 |
| Alakuijala, L; Eloranta, TO; Lindqvist, L; Smith, TK | 1 |
| Horne, DW | 1 |
| Runciman, WB; Snoswell, AM; Xue, GP | 1 |
| Davis, DW; Hawkins, RA; Viña, JR | 1 |
| Dyer, JR; Greenwood, CE | 1 |
| Boss, GR; Erbe, RW; Levitt, LJ | 1 |
| Loo, G; Smith, JT | 1 |
| Freeze, HH; Wolgast, D | 1 |
| Finkelstein, JD; Martin, JJ | 2 |
| Allen, ER; Freese, E; Orrego, C; Wabiko, H | 1 |
| Finkelstein, JD; Harris, BJ; Martin, JJ | 2 |
| Bârzu, O; Belfaiza, J; Cohen, GN; Guillou, Y; Guiso, N; Perrin, D; Saint-Girons, I | 1 |
| Coombs, GH; Sanderson, BE; Thong, KW | 1 |
| Eloranta, TO; Hyvönen, T; Pajula, RL; Smith, TK | 1 |
| Makar, AB; Tephly, TR | 2 |
| Siegel, FL; Vincent, PL | 1 |
| Benevenga, NJ; Engstrom, MA | 1 |
| Cacciapuoti, G; Cartení-Farina, M; Gambacorta, A; Porcelli, M | 1 |
| Augé, J; Christa, L; Kersual, J; Pérignon, JL | 1 |
| Abe, Y; Ido, T; Ishiwata, K; Iwata, R; Matsuzawa, T | 1 |
| Bloch, K; Chin, J | 1 |
| Barak, AJ; Beckenhauer, HC | 1 |
| Borczuk, A; Stock, A; Stock, J | 1 |
| Alonso, T; Chiang, PK; Gordon, RK; Miura, GA | 1 |
| Djurhuus, R; Lillehaug, JR; Male, R; Svardal, AM; Ueland, PM | 1 |
| Hariyama, H; Moriguchi, K; Sato, H | 1 |
| Ballou, CE; Weisman, LS | 1 |
| Bottiglieri, T; Clayton, PT; Hyland, K; Leonard, JV; Perry, J; Smith, I; Wendel, U | 1 |
| De Clercq, E; Durbin, RK; Stollar, V | 1 |
| Alarcon, RD; Allison, JG; Antun, F; Bahar, B; Cates, A; Keriotis, JT; Monti, JA; Smythies, JR; Tolbert, LC; Walter-Ryan, W | 1 |
| Don, HS; Shiao, MS | 1 |
| Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Creasia, D; Hoover, KL; Mikol, YB; Poirier, LA; Shivapurkar, N; Wilson, MJ | 1 |
| Stipanuk, MH | 2 |
| Matos, JR; Raushel, FM; Wong, CH | 1 |
| Hampton, A; Kappler, F; Vrudhula, VM | 1 |
| Badakhsh, S; Barak, AJ; Beckenhauer, HC; Tuma, DJ | 1 |
| Poirier, LA | 2 |
| Germain, BJ; O'Connor, CM | 1 |
| Lakher, MB; Wurtman, RJ | 1 |
| Duerre, JA; Wallwork, JC | 2 |
| Carrera, CJ; Carson, DA; Kajander, EO; Kubota, M; Montgomery, JA | 1 |
| Cresteil, D; Lemonnier, A; Lemonnier, F; Ozturk, M | 2 |
| Geller, AM; Jernigan, HM; Kotb, MY; Kredich, NM | 1 |
| Borchardt, RT; Clark, RS; Keller, BT; Pegg, AE | 1 |
| Brot, N; Coleman, T; Greene, RC; Redfield, B; Saint-Girons, I; Shoeman, R; Smith, AA; Weissbach, H | 1 |
| Bottiglieri, T; Nunn, JF; Rossiter, J; Sharer, NM | 1 |
| Refsum, H; Svardal, A; Ueland, PM | 1 |
| Hirayama, N; Kurata, K; Senda, M; Yamanouchi, K; Yoshikawa, Y | 1 |
| Poirier, LA; Shivapurkar, N | 3 |
| Brown, FC; Zawad, JS | 1 |
| Amess, JA; Amos, RJ; Sourial, NA | 1 |
| Snoswell, AM; Xue, GP | 1 |
| Tarr, HL | 1 |
| Duerre, JA; Fetters, HA; Kelleher, J | 1 |
| van der Westhuyzen, J | 1 |
| Hartley, R; Smith, JA | 1 |
| Räihä, NC | 1 |
| Nakamura, KD; O'Connor, ML; Parks, LW; Trewyn, RW | 1 |
| Fujii, K; Huennekens, FM | 1 |
| Gawthorne, JM; Smith, RM | 1 |
| Cossins, EA; Lor, KL | 1 |
| Qadri, SM; Williams, RP | 1 |
| Delk, AS; Rabinowitz, JC; Romeo, JM | 1 |
| Krüger, FW; Rücker, U; Wiessler, M | 1 |
| Alpert, NR; Hamrell, BB; Russell, DH; Shiverick, KT | 1 |
| Cier, JF; Pérés, G; Peyrin, L | 1 |
| Chen, GS; Metzenberg, RL | 1 |
| Salvatore, F; Shapiro, SK; Utili, R; Zappia, V | 1 |
| Cicala, V; Illiano, G; Utili, R | 1 |
| Hurlbert, RB; Liau, MC; O'Rourke, CM | 1 |
| Thompson, W; Wong, ER | 1 |
| Cortellaro, M | 2 |
| Granieri, A; Scarano, E; Tosi, L | 1 |
| Jungermann, KA; Kirchniawy, FH; Thauer, RK | 1 |
| Tait, GH | 1 |
| Nakamura, KD; Schlenk, F | 1 |
| Stokstad, EL; Vidal, AJ | 1 |
| Inukai, S; Sato, K; Shimizu, S | 1 |
| Craddock, VM | 1 |
| Abdel-Latif, AA; Morganstern, RD | 1 |
| Cello, JP; Finkelstein, JD; Kyle, WE | 1 |
| Ceccato, S; Passeri, M | 1 |
| Britton, G; Goodwin, TW; Singh, RK | 1 |
| Piekarowicz, A | 1 |
| Decter, JB; Mansouri, A; Silber, R | 1 |
| Parks, LW; Starr, PR | 1 |
| Lawrence, DA | 1 |
| Murphy, JT; Spence, KD | 1 |
| Chou, TC; Talalay, P | 1 |
| Greene, RC; Kung, HF; Spears, C; Weissbach, H | 1 |
| Armstrong, JB | 2 |
| Pegg, AE | 3 |
| Berdahl, BJ; Borek, E; Low, M; Schein, A | 1 |
| Bailey, RB; Parks, LW | 1 |
| Flavin, M; Savin, MA; Slaughter, C | 1 |
| Dubert, JM; Garbit, F; Nau, F | 1 |
| Mertz, JE; Spence, KD | 1 |
| Chou, TC; Lombardini, JB | 1 |
| Cohen, SS; Lapi, L; Massey, S; Rubenstein, KE; Streibel, E | 1 |
| Mardon, DN | 1 |
| Farber, E | 1 |
| Antoniewski, J; Cherest, H; Robichon-Szulmajster, H; Surdin-Kerjan, Y | 1 |
| Coch, EH; Greene, RC; Hunter, JS | 1 |
| Balish, E | 2 |
| Antoniewski, J; Cherest, H; de Robichon-Szulmajster, H; Surdin-Kerjan, Y | 1 |
| Greene, RC; Kung, HF; Spears, C; Weissbach, H; Williams, RD | 1 |
| Greene, RC | 1 |
| Ferro, AJ; Spence, KD | 1 |
| Jaenicke, L; Rüdiger, H | 1 |
| Antoniewski, J; Robichon-Szulmajster, H | 1 |
| Dudock, B; Michael, M; Roe, B | 1 |
| Cho, TC; Talalay, P | 1 |
| Chou, TC; Lombardini, JB; Talalay, P | 1 |
| Hobson, AC; Smith, DA | 1 |
| Kowalska, IM; Pieniazek, NJ; Stepień, PP | 1 |
| Meedel, TH; Pizer, LI | 1 |
| Agris, PF; Brown, GM; Rajbhandary, UL; Spremulli, LL | 1 |
| Cox, GS; Kaback, HR; Weissbach, H | 1 |
| de Robichon-Szulmajster, H; Masselot, M | 2 |
| Stadtman, TC | 1 |
| Coulter, AW; Lombardini, JB; Talalay, P | 2 |
| Bayev, AA; Shershneva, LP; Venkstern, TV | 1 |
| Hobson, AC | 1 |
| Bouche, JP | 1 |
| Axelrod, J; Cohn, CK; Vesell, ES | 1 |
| Hutson, NK; Shapiro, SK; Spence, KD | 1 |
| Boucher, Y; Lachance, RA; Paquin, R | 1 |
| Jacob, M; Judes, C | 1 |
| Borun, TW; Lee, HW; Paik, WK | 1 |
| Abrahamson, L; Allamong, BD | 1 |
| Lombardini, JB; Talalay, P | 1 |
| Cox, R; Martin, JT; Shinozuka, H | 1 |
| Cohn, CK; Dunner, DL; Weinshilboum, RM; Wyatt, RJ | 1 |
| Hill, LJ; Martin, WG | 1 |
| Gandy, G; Jacobson, W; Sidman, R | 1 |
| Fujita, T; Suzuoki, Z | 1 |
| Finkelstein, JD; Harris, B | 1 |
| Heby, O; Russell, DH; Sauter, S | 1 |
| Dainko, JL; Schlenk, F; Zydek-Cwick, CR | 1 |
| Adams, RL; Hogarth, C | 1 |
| Acheampong-Mensah, D; Feuer, G | 1 |
| Cocchiara, R; Eremenko, T; Geraci, D; Granieri, A; Scarano, E; Volpe, P | 1 |
| Jensen, LS; Kushwaha, RP | 1 |
| Hulbert, PB | 1 |
| Ordonez, LA; Rubin, RA; Wurtman, RJ | 1 |
| Coulter, AW; Lombardini, JB; Sufrin, JR; Talalay, P | 1 |
| Borek, E; Ryan, AM | 1 |
| Kuchino, Y; Nishimura, S; Seno, T | 1 |
| Huang, HH; Johnson, BC; Ma, J | 1 |
| Henningsson, A; Isaksson, L; Svensson, I | 1 |
| Burch, MK; Lombardini, JB; Talalay, P | 1 |
| Bohuon, C; Caillard, L | 1 |
| McVicker, TA; Russell, DH | 1 |
| Eisenberg, MA; Stoner, GL | 1 |
| Taylor, RT; Weissbach, H | 1 |
| Brush, A; Paulus, H | 1 |
| Baldessarini, RJ; Matthysse, S | 1 |
| Ebel, J; Grisebach, H; Hahlbrock, K | 1 |
| Ayala, F; Zappia, V | 1 |
| Gasbarrini, G; Labò, G; Miglio, F | 1 |
| Cavalieri, U; Leonelli, G | 1 |
| Fitzgerald, PJ; Marsh, WH; Parsa, I | 1 |
| Chow, CM; McConnell, WB; Nigam, SN | 1 |
| Amos, H; Stevens, RH | 1 |
| Barchas, JD; Ciaranello, RD; Dankers, HJ | 1 |
| Menci, S; Orsucci, PL | 1 |
| Kim, S; Lee, HW; Paik, WK | 1 |
| Draper, MW; Mangum, JH; North, JA | 1 |
| Killick, KA | 1 |
| Baldessarini, RJ; Matthysse, S; Vogt, M | 1 |
| Brodie, JD; Burke, GT; Mangum, JH | 1 |
| Lipinski, J; Matthysse, S; Shih, V | 1 |
| Craddock, VM; Turberville, C | 1 |
| Krzysik, B; McManus, I; Vergnes, JP | 1 |
| Lyon, GM | 1 |
| Curri, SB | 1 |
| Borek, E; Loeb, LA; Sharma, OK | 1 |
| Icekson, I; Kaye, AM; Lindner, HR | 1 |
| Estes, LW; Farber, E; Shinozuka, H | 1 |
| Chen, SS; Duerre, JA; Walgate, JH | 1 |
| Lombardini, JP; Russell, DH | 1 |
| Spence, KD | 1 |
| Piatigorsky, J; Rothschild, SS | 1 |
| Demain, AL; White, RF | 1 |
| Matsumoto, C; Sawai, Y; Suma, Y; Tsukada, K | 1 |
| Crang, AJ; Jacobson, W | 1 |
| Dev, VG; Mixon, JC | 1 |
| Macfarlane, DE | 1 |
| Hoffman, RM | 2 |
| Benevenga, NJ | 2 |
| Cornatzer, WE; Haning, JA; Hoffman, DR | 1 |
| Niwano, M; Taylor, BL | 1 |
| Coalson, DW; Hoffman, RM; Mecham, JO; Stern, PH | 1 |
| Hoffman, RM; Mecham, JO; Stern, PH; Wallace, CD | 1 |
| Smythies, JR | 2 |
| Cooper, AJ | 1 |
| Javor, GT | 1 |
| Freese, E; Freese, EB; Hartig, A; Olempska-Beer, Z | 1 |
| Clarke, S; Lou, LL; McFadden, PN; O'Connor, CM | 1 |
| Panasenko, SM | 1 |
| Clarke, S; O'Connor, CM | 1 |
| Claverie, N; Danzin, C; Wagner, J | 1 |
| Hoffman, RM; Stern, PH | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Gibson, J; Van der Westhuyzen, J | 1 |
| Barber, JR; Clarke, S | 1 |
| Metz, J; van der Westhuyzen, J | 1 |
| Branno, M; De Franciscis, V; Tosi, L | 1 |
| Brown, L; Sourial, NA | 1 |
| Geresh, S; Gross, A; Whitesides, GM | 1 |
| Hoffman, RM; Stern, PH; Wallace, CD | 1 |
| Borchardt, RT; Keller, BT | 1 |
| Poirier, LA; Shivapurkar, N; Wilson, MJ | 1 |
| DiMaria, P; Kim, S; Ro, JY | 1 |
| Keith, DD; Porter, CW; Sufrin, JR | 1 |
| Follmann, H; Theiss, G | 1 |
| Freese, E; Ochi, K | 1 |
| Buist, NR; Gaull, GE; Jhaveri, BM; Tallan, HH | 1 |
| Axelrod, J; Kloog, Y; Spector, I | 1 |
| Chanarin, I; Deacon, R; Jennings, P; Lumb, M; Perry, J; Purkiss, P; Sharer, N | 1 |
| Barra, D; Bernardi, L; Bombardieri, G; Castrini, G; Di Palma, A; Pappalardo, G | 1 |
| Clarke, S; Oden, KL | 1 |
| Bloch, CA; German, DC; Kredich, NM | 1 |
| Bors, W; Elstner, EF; Michel, C; Saran, M | 1 |
| Koshland, DE; Stock, JB | 1 |
| Chelsky, D; Dahlquist, FW | 1 |
| Dai, RM; Shen, XR; Sun, YK; Wu, AZ | 1 |
| Borchardt, RT; Eiden, LE; Rutledge, CO | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, WE; Martin, JJ | 1 |
| Engelsen, SJ; Zatz, M | 1 |
| Barak, AJ; Beckenhauer, HC; Tuma, DJ | 1 |
| Tisdale, MJ | 2 |
| Döbeli, H; Nüesch, J | 1 |
| Dini, G; Franconi, F; Martini, F | 1 |
| Beratis, NG; Gaull, GE; Guarini, L; Sturman, JA | 1 |
| Curti, D; Raimondo, S; Villa, RF | 1 |
| Ozaki, H; Shiio, I | 1 |
| Doyle, RL; Porta, R; Schatz, RA; Sellinger, OZ; Tatter, SB; Wilens, TE | 1 |
| Green, GA; Kalra, VK | 1 |
| Kim, S; Magee, PN; Neilan, B; Paik, WK; Ro, JY | 1 |
| Mikol, YB; Poirier, LA | 1 |
| Balint, R; Cohen, S; Marcu, D; Sindhu, RK | 1 |
| Galletti, P; Kim, S; Paik, WK | 1 |
| Bone, AH; Taufek, HR | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR; Marion, DW | 1 |
| Claeys, KM; Foss, HM; Roberts, CJ; Selker, EU | 1 |
| Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G | 1 |
| Granzin, J; Labahn, J; Saenger, W; Schildkraut, I; Schluckebier, G | 1 |
| Markham, GD; McQueney, MS | 1 |
| Bacchi, CJ; Garofalo-Hannan, J; Goldberg, B; Lyte, P; Rattendi, D; Yarlett, N | 1 |
| Shi, W; Zusman, DR | 1 |
| Blom, HJ; Copius Peereboom-Stegeman, JH; Deabreu, RA; Eskes, TK; Noordhoek, J; Trijbels, FJ; Vanaerts, LA | 1 |
| Christman, JK; Cravo, ML; Fleet, JC; Kim, YI; Mason, JB; Ordovas, J; Salomon, RN; Selhub, J; Smith, D | 1 |
| Croteau, S; Menezo, Y | 1 |
| Wood, RC | 1 |
| Barry, JA; Gillies, RJ; Ross, BD | 1 |
| Cibert, C; Jacquemin-Faure, I; Laporte, J; Surdin-Kerjan, Y; Thomas, D | 1 |
| Phillips, K; Phillips, SE | 1 |
| Huang, HY; Lu, SC | 1 |
| Drummond, JT; Matthews, RG | 1 |
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| Chen, K; Gong, J; Liu, F; Peng, Y; Qiao, Y; Si, C; Song, F; Wang, P; Wang, X; Zhou, H | 1 |
| Lee, JM; Oh, MK; Park, BS; Park, MH | 1 |
| Feng, J; Feng, P; Gao, SJ; Gao, X; Huang, Y; Meng, W; Qin, C; Zhang, X | 1 |
| Clément, A; Clément, P; Menezo, YJR; Viot, G | 1 |
| Koutmos, M; Mendoza, J; Purchal, M; Yamada, K | 1 |
| Kim, IK; Kim, KJ; Kim, S; Lee, S | 1 |
| Chen, J; Cui, X; Fang, N; Wu, Y; Xiao, D; Yu, S | 1 |
| Broderick, JB; Broderick, WE; Hoffman, BM; Lundahl, MN; Yang, H | 1 |
| Dong, M; Wang, W | 1 |
83 review(s) available for methionine and s-adenosylmethionine
| Article | Year |
|---|---|
B12 -- dependent methionine synthetase as a potential target for cancer chemotherapy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cells, Cultured; Cobamides; Enzyme Activation; Flavoproteins; Leukemia L1210; Methionine; Methyltransferases; Mice; NADP; Neoplasms; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1976 |
Methyl biogenesis.
Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates | 1978 |
Cystinosis--a review.
Topics: Animals; Birds; Cystine; Cystinosis; Dimercaprol; Homocystine; Humans; Hydrogen Sulfide; Kidney Transplantation; Lysosomes; Mammals; Methionine; Organoids; Penicillamine; S-Adenosylmethionine; Thiosulfates; Transplantation, Homologous | 1975 |
Protein methylation: chemical, enzymological, and biological significance.
Topics: Amino Acids; Animals; Arginine; Cations, Divalent; Chloramphenicol; DNA; Glycine; Humans; Kinetics; Liver; Lysine; Methionine; Methyltransferases; Molecular Weight; Organ Specificity; Proteins; Rats; S-Adenosylmethionine; Species Specificity; Tetrahymena; Thymus Gland; Time Factors; tRNA Methyltransferases | 1975 |
Biological transmethylation involving S-adenosylmethionine: development of assay methods and implications for neuropsychiatry.
Topics: Acetylserotonin O-Methyltransferase; Animals; Apomorphine; Blood Platelets; Brain; Histamine; Humans; Leukemia; Levodopa; Methionine; Methionine Adenosyltransferase; Methyltransferases; Monoamine Oxidase Inhibitors; Pyrogallol; Rabbits; Rats; S-Adenosylmethionine; Schizophrenia; Serotonin; Tetrahydrofolates | 1975 |
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.
Topics: Amino Acid Metabolism, Inborn Errors; Cystathionine; Homocysteine; Humans; Methionine; Methylation; S-Adenosylmethionine | 1992 |
Mechanisms and consequences of the impaired trans-sulphuration pathway in liver disease: Part I. Biochemical implications.
Topics: Humans; Liver; Liver Diseases; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 1990 |
Mechanisms and consequences of the impaired trans-sulphuration pathway in liver disease: Part II. Clinical consequences and potential for pharmacological intervention in cirrhosis.
Topics: Amino Acids; Humans; Liver Cirrhosis; Methionine; S-Adenosylmethionine | 1990 |
Physiological methylation in carcinogenesis.
Topics: Animals; Choline Deficiency; DNA; Humans; Liver Neoplasms; Methionine; Methylation; Oxidation-Reduction; S-Adenosylmethionine | 1990 |
The influence of ethanol on hepatic transmethylation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Ethanol; Humans; Liver; Methionine; Rats; S-Adenosylmethionine | 1988 |
Metabolism of sulfur-containing amino acids.
Topics: Adenosylhomocysteinase; Animals; Carboxy-Lyases; Cysteine; Female; Homocysteine; Humans; Hydrolases; Isoenzymes; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Polyamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Taurine; Transaminases | 1986 |
Biochemical basis for nutritional management of preterm infants.
Topics: Acetoacetates; Adenosine Triphosphate; Amino Acids; Animals; Brain; Cyclic AMP; Cystathionine; Cystine; Enzyme Induction; Female; Fumarates; Homogentisic Acid; Humans; Hydro-Lyases; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Liver; Lyases; Maternal-Fetal Exchange; Methionine; Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pregnancy; S-Adenosylmethionine; Transferases; Tyrosine; Tyrosine Transaminase | 1974 |
ATP and cell integrity.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Brain; Cell Nucleus; Cells; Ethionine; Female; Glucosephosphates; Glycerophosphates; Guinea Pigs; Hexosephosphates; Humans; Ischemia; Kidney; Liver; Male; Methionine; Mitochondria; Models, Biological; Oxidative Phosphorylation; Protein Biosynthesis; Rats; Ribosomes; RNA; S-Adenosylmethionine; Triglycerides | 1973 |
The biosynthesis of methionine.
Topics: Animals; Apoproteins; Bacteria; Catalysis; Chemical Phenomena; Chemistry; Cobamides; Drug Stability; Enzyme Activation; Escherichia coli; Flavins; Homocysteine; Methionine; Methyltransferases; Molecular Weight; Oxidation-Reduction; Plants; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1973 |
Selenium biochemistry.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Clostridium; Electron Transport; Escherichia coli; Glycine; Metalloproteins; Methionine; Nucleotidyltransferases; Plants; Radioisotopes; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Selenium; Sulfates | 1974 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
Nitrous oxide, vitamin B12 deficiency and the methyl folate trap.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Humans; Liver; Macaca fascicularis; Methionine; Methylmalonyl-CoA Mutase; Nervous System Diseases; Nitrous Oxide; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 Deficiency | 1982 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Evidence for alternative pathways of methionine catabolism.
Topics: Animals; Betaine; Carbon Dioxide; Choline; Decarboxylation; Diet; Homocystinuria; Humans; Liver; Methionine; Models, Biological; Oxidation-Reduction; Propionates; S-Adenosylmethionine; Sarcosine; Transaminases | 1984 |
Biochemistry of sulfur-containing amino acids.
Topics: Adenosine; Amino Acid Metabolism, Inborn Errors; Animals; Cysteine; Deoxyadenosines; Homocysteine; Humans; Methionine; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; S-Adenosylmethionine; Structure-Activity Relationship; Sulfur; Sulfurtransferases; Thionucleosides; Thiosulfate Sulfurtransferase | 1983 |
Methyl group deficiency in hepatocarcinogenesis.
Topics: Animals; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Methylation; Oncogenes; S-Adenosylmethionine | 1994 |
Metabolism of methionine in liver disease.
Topics: Clinical Trials as Topic; Humans; Liver; Liver Diseases; Methionine; S-Adenosylmethionine | 1996 |
Disturbances of one-carbon metabolism in neuropsychiatric disorders: a review.
Topics: Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Neurocognitive Disorders; S-Adenosylmethionine; Schizophrenia | 1997 |
S-adenosylmethionine synthesis: molecular mechanisms and clinical implications.
Topics: Animals; Chemical and Drug Induced Liver Injury; Gene Expression Regulation, Enzymologic; Humans; Liver; Liver Diseases; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Species Specificity | 1997 |
Parasite sulphur amino acid metabolism.
Topics: Amino Acids, Sulfur; Animals; Cystathionine; Cysteine; Deoxyadenosines; Eukaryota; Helminthiasis; Helminths; Humans; Methionine; Protozoan Infections; S-Adenosylmethionine; Thionucleosides | 1997 |
The metabolism of homocysteine: pathways and regulation.
Topics: Animals; Homocysteine; Humans; Hydrolysis; Methionine; Methylation; S-Adenosylmethionine | 1998 |
The specific features of methionine biosynthesis and metabolism in plants.
Topics: Cystathionine; Homocystine; Methionine; Models, Biological; Molecular Sequence Data; Plants; S-Adenosylmethionine | 1998 |
New approaches to understanding the etiology and treatment of total parenteral nutrition-associated cholestasis.
Topics: Animals; Cholecystokinin; Cholestasis; Humans; Methionine; Parenteral Nutrition, Total; Phytosterols; S-Adenosylmethionine; Ursodeoxycholic Acid | 1999 |
Molecular genetics of hepatic methionine adenosyltransferase deficiency.
Topics: Adenosine Triphosphate; Humans; Isoenzymes; Liver; Methionine; Methionine Adenosyltransferase; Mutation; S-Adenosylmethionine | 2000 |
Sulfur metabolism in Escherichia coli and related bacteria: facts and fiction.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Biological Transport, Active; Cysteine; Escherichia coli; Genes, Bacterial; Methionine; Methylation; Molecular Sequence Data; Oxidation-Reduction; S-Adenosylmethionine; Selenium; Sulfonic Acids; Sulfur | 2000 |
Homocysteine: a history in progress.
Topics: History, 19th Century; History, 20th Century; Homocysteine; Homocystinuria; Humans; Insulin; Methionine; Neural Tube Defects; North America; Research; S-Adenosylmethionine; Workforce | 2000 |
Pathways and regulation of homocysteine metabolism in mammals.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates | 2000 |
Role of polyamines and ethylene as modulators of plant senescence.
Topics: Adenosylmethionine Decarboxylase; Arginine; Cellular Senescence; Ethylenes; Gene Expression Regulation, Plant; Homeostasis; Methionine; Models, Biological; Ornithine Decarboxylase; Plant Development; Plant Growth Regulators; Plant Physiological Phenomena; Plant Proteins; Polyamines; S-Adenosylmethionine | 2000 |
Roles of homocysteine in cell metabolism: old and new functions.
Topics: Cardiovascular Diseases; Cell Physiological Phenomena; Female; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nervous System Malformations; Pregnancy; Pregnancy Complications; RNA, Transfer, Amino Acyl; S-Adenosylmethionine | 2001 |
Nutritional regulation of homocysteine: effects of drugs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Drug Interactions; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methionine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6 | 2001 |
Role of abnormal methionine metabolism in alcoholic liver injury.
Topics: Animals; Humans; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine | 2002 |
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].
Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency | 2003 |
Structure and function of radical SAM enzymes.
Topics: Bacterial Proteins; Coproporphyrinogen Oxidase; Deoxyadenosines; Free Radicals; Iron; Methionine; Nitrogen; Oxygen; Protein Structure, Tertiary; S-Adenosylmethionine; Sulfur; Sulfurtransferases | 2004 |
The impact of metabolism on DNA methylation.
Topics: Alzheimer Disease; Animals; Arteriosclerosis; DNA Methylation; Folic Acid; Gene Expression Regulation; Glycine N-Methyltransferase; Homocysteine; Humans; Methionine; Methyltransferases; Models, Biological; S-Adenosylmethionine | 2005 |
Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.
Topics: Animals; Cell Death; Central Nervous System Depressants; Ethanol; Female; Hepatocytes; Humans; Isoenzymes; Liver; Liver Diseases, Alcoholic; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 2005 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
The sulfur-containing amino acids: an overview.
Topics: Allosteric Regulation; Amino Acids, Sulfur; Animals; Cysteine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Proteins; S-Adenosylmethionine; Taurine | 2006 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
Assessing the effects of high methionine intake on DNA methylation.
Topics: Animals; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Amino acids and the regulation of methyl balance in humans.
Topics: Amino Acids; Animals; Creatine; Epigenesis, Genetic; Humans; Liver Diseases; Methionine; Methylation; Mice; Mutation; Neural Tube Defects; Polymorphism, Genetic; S-Adenosylmethionine | 2007 |
Emerging aspects of gut sulfur amino acid metabolism.
Topics: Amino Acids, Sulfur; Biological Availability; Cysteine; DNA Methylation; Gastrointestinal Diseases; Homocysteine; Humans; Intestinal Absorption; Intestinal Mucosa; Methionine; Nutritional Physiological Phenomena; Oxidation-Reduction; S-Adenosylmethionine | 2007 |
Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition.
Topics: Betaine; Cytokines; Dietary Supplements; Environmental Exposure; Fatty Liver; Female; Humans; Insulin Resistance; Life Style; Liver; Liver Cirrhosis; Metabolic Syndrome; Methionine; Middle Aged; Mitochondrial Diseases; Oxidative Stress; S-Adenosylmethionine; United States; Vitamin E; Xenobiotics; Zinc | 2007 |
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
Topics: Animals; Betaine; Disease Models, Animal; Folic Acid; Humans; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine | 2007 |
The methylation, neurotransmitter, and antioxidant connections between folate and depression.
Topics: Antioxidants; Biopterins; Depression; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Neurotransmitter Agents; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2008 |
Structure-function relationships in methionine adenosyltransferases.
Topics: Animals; Crystallography, X-Ray; Humans; Isoenzymes; Methionine; Methionine Adenosyltransferase; Models, Molecular; Protein Conformation; Protein Folding; Protein Subunits; S-Adenosylmethionine; Structure-Activity Relationship | 2009 |
Alcoholic liver disease and methionine metabolism.
Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
The logic of the hepatic methionine metabolic cycle.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Glycine N-Methyltransferase; Humans; Liver; Metabolic Networks and Pathways; Methionine; Methionine Adenosyltransferase; Methylation; Methyltransferases; Models, Biological; S-Adenosylmethionine | 2010 |
Current understanding of the factors regulating methionine content in vegetative tissues of higher plants.
Topics: Animal Feed; Carbon-Oxygen Lyases; Crops, Agricultural; Gene Expression Regulation, Plant; Methionine; Methyltransferases; Plants; S-Adenosylmethionine; Seed Storage Proteins | 2010 |
Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism.
Topics: 4-Butyrolactone; Adenine; Bacteria; Biofilms; Homoserine; Lactones; Metabolic Networks and Pathways; Methionine; Models, Biological; N-Glycosyl Hydrolases; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine; Vitamins | 2011 |
Vitamin-dependent methionine metabolism and alcoholic liver disease.
Topics: Alcoholism; Animals; Epigenomics; Ethanol; Folic Acid Deficiency; Gene Expression Regulation; Humans; Liver; Liver Diseases, Alcoholic; Malnutrition; Methionine; Models, Animal; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamins | 2011 |
Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.
Topics: Animals; Antigen Presentation; Betaine; Ethanol; Hepatitis C; Humans; Interferons; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; Methyltransferases; Proteasome Endopeptidase Complex; S-Adenosylmethionine; Tumor Necrosis Factor-alpha | 2013 |
Methionine adenosyltransferase I/III deficiency: neurological manifestations and relevance of S-adenosylmethionine.
Topics: Alleles; Amino Acid Metabolism, Inborn Errors; Brain; Demyelinating Diseases; Diet; Genetic Testing; Glycine N-Methyltransferase; Humans; Infant, Newborn; Isoenzymes; Methionine; Methionine Adenosyltransferase; Mutation; S-Adenosylmethionine; Severity of Illness Index | 2012 |
B-Vitamin dependent methionine metabolism and alcoholic liver disease.
Topics: Epigenesis, Genetic; Ethanol; Folic Acid; Gene Expression Regulation; Humans; Kidney; Liver; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine; Vitamin B Complex; Vitamin B Deficiency | 2013 |
Methionine metabolic pathway in alcoholic liver injury.
Topics: Aminobutyrates; Betaine; Biomarkers; Cystathionine; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Metabolic Networks and Pathways; Methionine; S-Adenosylmethionine | 2013 |
Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis.
Topics: Adenine; Arabidopsis; Carbon; Cytosol; Ethylenes; Gene Expression Regulation, Plant; Iron; Methionine; Oryza; Polyamines; S-Adenosylmethionine; Sulfur | 2013 |
Methyl nutrients, DNA methylation, and cardiovascular disease.
Topics: Amino Acids; Atherosclerosis; Cardiovascular Diseases; Cysteine; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Status; Risk Factors; S-Adenosylmethionine; Vitamin B Complex | 2014 |
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine | 2013 |
Lifetime requirement of the methionine cycle for neuronal development and maintenance.
Topics: Developmental Disabilities; Female; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Prenatal Care; S-Adenosylmethionine; Vitamin B 12; Vitamin B Complex | 2014 |
One-carbon metabolism and epigenetics: understanding the specificity.
Topics: Animals; Chromatin; Epigenesis, Genetic; Epigenomics; Folic Acid; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Metabolic Networks and Pathways; Methionine; Methylation; S-Adenosylmethionine; Substrate Specificity | 2016 |
AdoMet analog synthesis and utilization: current state of the art.
Topics: Animals; Biocatalysis; Catalysis; Humans; Kinetics; Metabolic Engineering; Methionine; S-Adenosylmethionine; Substrate Specificity; Synthetic Biology | 2016 |
Consensus recommendations for the diagnosis, treatment and follow-up of inherited methylation disorders.
Topics: Consensus; Homocysteine; Humans; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; Neonatal Screening; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
A genetic method to enhance the accumulation of S-adenosylmethionine in yeast.
Topics: Methionine; Pichia; S-Adenosylmethionine; Saccharomyces cerevisiae | 2017 |
Lean Body Mass Harbors Sensing Mechanisms that Allow Safeguarding of Methionine Homeostasis.
Topics: Betaine-Homocysteine S-Methyltransferase; Biomarkers; Body Composition; Body Mass Index; Cystathionine beta-Synthase; Diet, Protein-Restricted; Dietary Proteins; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Methionine; S-Adenosylmethionine | 2017 |
New insights into the metabolism of aspartate-family amino acids in plant seeds.
Topics: Amino Acids; Aspartic Acid; Gene Expression Regulation, Plant; Lysine; Methionine; S-Adenosylmethionine; Seeds | 2018 |
Oxidation Resistance of the Sulfur Amino Acids: Methionine and Cysteine.
Topics: Amino Acids, Sulfur; Antioxidants; Cysteine; Glutathione; Hydrogen Sulfide; Methionine; Oxidation-Reduction; Reactive Oxygen Species; S-Adenosylmethionine; Taurine | 2017 |
Oral Methioninase for Covid-19 Methionine-restriction Therapy.
Topics: Administration, Oral; Antiviral Agents; Bacterial Proteins; Betacoronavirus; Carbon-Sulfur Lyases; Clinical Trials as Topic; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Humans; Lymphocyte Activation; Macrophage Activation; Meta-Analysis as Topic; Methionine; Methylation; Pandemics; Pneumonia, Viral; Pseudomonas putida; Recombinant Proteins; RNA Caps; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; T-Lymphocyte Subsets; Virus Replication | 2020 |
Epigenetic remodeling of chromatin in human ART: addressing deficiencies in culture media.
Topics: Amino Acids; Blastocyst; Chromatin; Chromatin Assembly and Disassembly; Congenital Abnormalities; Culture Media; DNA Methylation; DNA Repair; Embryo Culture Techniques; Embryonic Development; Endocrine Disruptors; Female; Genomic Imprinting; Glucose; Humans; Infant, Newborn; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oocytes; Oxidative Stress; Pregnancy; Reproductive Techniques, Assisted; S-Adenosylmethionine | 2020 |
Metabolism of Sulfur-Containing Amino Acids: How the Body Copes with Excess Methionine, Cysteine, and Sulfide.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Cystathionine beta-Synthase; Cysteine; Glycine N-Methyltransferase; Homocysteine; Humans; Hydrogen Sulfide; Liver; Methionine; S-Adenosylmethionine; Serine; Sulfides; Sulfur; Thiosulfates | 2020 |
Lessons Learned from Inherited Metabolic Disorders of Sulfur-Containing Amino Acids Metabolism.
Topics: Amino Acids, Sulfur; Animals; Brain Diseases; Cysteine; Glutathione; Homocysteine; Homocystinuria; Humans; Hydrogen Sulfide; Liver; Metabolic Diseases; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Sulfites; Sulfur; Sulfur Compounds | 2020 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
Biomedical applications of methionine-based systems.
Topics: Cell Proliferation; COVID-19; COVID-19 Drug Treatment; Docetaxel; Humans; Liver Diseases; Methionine; Nanoparticles; Neoplasms; S-Adenosylmethionine; SARS-CoV-2 | 2021 |
Targeting the methionine-methionine adenosyl transferase 2A- S -adenosyl methionine axis for cancer therapy.
Topics: Animals; Carcinogenesis; Humans; Mammals; Methionine; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine | 2022 |
Overview of Methionine Adenosyltransferase 2A (MAT2A) as an Anticancer Target: Structure, Function, and Inhibitors.
Topics: Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine | 2022 |
A patent review of MAT2a inhibitors (2018-2021).
Topics: Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; Patents as Topic; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2022 |
Keep a watchful eye on methionine adenosyltransferases, novel therapeutic opportunities for hepatobiliary and pancreatic tumours.
Topics: Gastrointestinal Neoplasms; Humans; Lipids; Methionine; Methionine Adenosyltransferase; Pancreatic Neoplasms; RNA; S-Adenosylmethionine | 2022 |
Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1α/PPAR-α Players.
Topics: Methionine; Neoplasms; Neoplastic Stem Cells; PPAR alpha; Racemethionine; S-Adenosylmethionine; Sirtuin 1 | 2022 |
Methyl Donors, Epigenetic Alterations, and Brain Health: Understanding the Connection.
Topics: Animals; Brain; Carbon; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Methionine; Micronutrients; S-Adenosylmethionine | 2023 |
[Synthesis and application of the methyl analogues of
Topics: Methionine; Methylation; Methyltransferases; Racemethionine; S-Adenosylmethionine | 2023 |
11 trial(s) available for methionine and s-adenosylmethionine
| Article | Year |
|---|---|
Metabolic consequences of folate-induced reduction of hyperhomocysteinemia in uremia.
Topics: Erythrocyte Membrane; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uremia | 1997 |
Demyelination and single-carbon transfer pathway metabolites during the treatment of acute lymphoblastic leukemia: CSF studies.
Topics: Antidotes; Antimetabolites, Antineoplastic; Central Nervous System; Child; Child, Preschool; Combined Modality Therapy; Demyelinating Diseases; Drug Interactions; Humans; Infant; Leucovorin; Methionine; Methotrexate; Myelin Basic Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; S-Adenosylmethionine; Tetrahydrofolates | 1998 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Treatment of AIDS-associated myelopathy with L-methionine: a placebo-controlled study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Double-Blind Method; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Muscles; Neural Conduction; S-Adenosylmethionine; Spinal Cord Diseases; Urination | 2004 |
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation | 2005 |
S-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trial.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Biopsy; Double-Blind Method; Female; Humans; Liver; Liver Diseases, Alcoholic; Male; Methionine; Middle Aged; Retrospective Studies; S-Adenosylmethionine; Treatment Outcome | 2011 |
Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder.
Topics: Biological Availability; Depressive Disorder, Major; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylhomocysteine; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2012 |
Short-term creatine supplementation does not reduce increased homocysteine concentration induced by acute exercise in humans.
Topics: Adolescent; Creatine; Cysteine; Dietary Supplements; Double-Blind Method; Energy Intake; Exercise; Feeding Behavior; Folic Acid; Glycine; Healthy Volunteers; Homocysteine; Humans; Male; Methionine; S-Adenosylmethionine; Soccer; Vitamin B 12 | 2014 |
Effects of S-adenosyl-L-Methionine Combined with Ursodesoxycholic Acid on Serum Endotoxin, MMP-9 and IL-18 in Neonates with Cholestasis.
Topics: Cholestasis; Cholestasis, Intrahepatic; Endotoxins; Female; Humans; Infant, Newborn; Interleukin-18; Matrix Metalloproteinase 9; Methionine; Pregnancy; Pregnancy Complications; S-Adenosylmethionine; Ursodeoxycholic Acid | 2021 |
[The results of phase III multicenter open randomized controlled study REM-Chol-III-16 in patients with intrahepatic cholestasis syndrome caused by chronic diffuse liver diseases].
Topics: Alkaline Phosphatase; Bilirubin; Cholestasis, Intrahepatic; gamma-Glutamyltransferase; Humans; Inosine; Meglumine; Methionine; Niacinamide; S-Adenosylmethionine; Succinic Acid; Transaminases | 2021 |
Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial.
Topics: Betaine; Child; Cystathionine beta-Synthase; Homocysteine; Homocystinuria; Humans; Methionine; Prospective Studies; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2022 |
783 other study(ies) available for methionine and s-adenosylmethionine
| Article | Year |
|---|---|
Discovery and characterization of a marine bacterial SAM-dependent chlorinase.
Topics: Bacterial Proteins; Crystallography, X-Ray; Genes, Bacterial; Hydrocarbons, Chlorinated; Lactones; Micromonosporaceae; Protein Conformation; Pyrroles; S-Adenosylmethionine; Substrate Specificity | 2008 |
Role of intrapartum hypoxia in carnitine nutritional status during the early neonatal period.
Topics: Carnitine; Chromatography, High Pressure Liquid; Esters; Fetal Hypoxia; Gestational Age; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Lysine; Methionine; Nutritional Status | 2001 |
Proteomic changes associated with diabetes in the BB-DP rat.
Topics: Animals; Carnitine; Citrate (si)-Synthase; Diabetes Mellitus, Type 1; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Gluconeogenesis; Glycolysis; Liver; Male; Methionine; Muscle, Skeletal; Myocardium; Proteomics; Rats; Rats, Inbred BB; Reactive Oxygen Species | 2009 |
Newborn screening and early biochemical follow-up in combined methylmalonic aciduria and homocystinuria, cblC type, and utility of methionine as a secondary screening analyte.
Topics: Algorithms; Carnitine; Demography; False Positive Reactions; Female; Follow-Up Studies; Genetic Association Studies; Homocystinuria; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Methionine; Methylmalonic Acid; Neonatal Screening; New York; Propionates; Referral and Consultation; Vitamin B 12 | 2010 |
Comparison of amino acids and acylcarnitines assay methods used in newborn screening assays by tandem mass spectrometry.
Topics: Amino Acids; Butanols; Carnitine; Humans; Infant, Newborn; Leucine; Metabolic Diseases; Methionine; Neonatal Screening; Palmitoylcarnitine; Phenylalanine; Quality Control; Tandem Mass Spectrometry | 2010 |
Metabolomic distinction of microvascular effects of lipoprotein apheresis--a pilot study.
Topics: Adult; Aged; Biomarkers; Blood Component Removal; Carnitine; Chi-Square Distribution; Decision Trees; Female; Humans; Hyperlipidemias; Lipoproteins; Lysophosphatidylcholines; Male; Metabolomics; Methionine; Microvessels; Middle Aged; Ornithine; Photic Stimulation; Pilot Projects; Retinal Vessels; Risk Assessment; Risk Factors; ROC Curve; Serine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Treatment Outcome | 2013 |
Identifying a metabolomics profile associated with masked hypertension in two independent cohorts: Data from the African-PREDICT and SABPA studies.
Topics: Amino Acids; Carnitine; Humans; Isoleucine; Leucine; Masked Hypertension; Metabolomics; Methionine; Phenylalanine; Valine | 2022 |
Purification and properties of S-adenosyl-L-homocysteine hydrolase from leaves of spinach beet.
Topics: Adenine; Cysteine; Deoxyadenosines; Homocysteine; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Methionine; Plants; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
Mechanism of inhibition of Chromatium D growth by L-methionine. Regulation of L-threonine biosynthesis by the intracellular level of S-adenosylmethionine.
Topics: Amino Acids; Aspartate Kinase; Aspartate-Semialdehyde Dehydrogenase; Chromatium; Homoserine Dehydrogenase; Kinetics; Lyases; Methionine; Phosphotransferases; Putrescine; S-Adenosylmethionine; Threonine | 1976 |
Methionine adenosyltransferase: kinetic properties of human and rat liver enzymes.
Topics: Adenosine Triphosphate; Animals; Cations, Divalent; Cations, Monovalent; Enzyme Activation; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Magnesium; Methionine; Methionine Adenosyltransferase; Potassium; Rats; S-Adenosylmethionine; Transferases | 1976 |
The transsulfuration pathway in Tetrahymena pyriformis.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Hydrogen-Ion Concentration; Hydrolases; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Temperature; Tetrahymena pyriformis | 1977 |
Effect of cystine on the metabolism on methionine in rats.
Topics: Adaptation, Physiological; Animals; Cystathionine; Cystathionine beta-Synthase; Cystine; Hydro-Lyases; Hydrogen-Ion Concentration; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; S-Adenosylmethionine; Threonine; Time Factors; Transferases | 1977 |
The effects of a marginally lipotrope-deficient diet on the hepatic levels of S-adenosylmethionine and on the urinary metabolites of 2-acetylaminofluorene in rats.
Topics: 2-Acetylaminofluorene; Animals; Benzopyrene Hydroxylase; Choline Deficiency; Diet; Female; Fluorenes; Folic Acid Deficiency; Glutathione; Hydroxyacetylaminofluorene; Lipotropic Agents; Liver; Male; Methionine; Microsomes, Liver; Nitroanisole O-Demethylase; Rats; S-Adenosylmethionine; Sex Factors | 1977 |
Biosynthesis of isoxazolinone of isoxazolinone amino acids: incorporation studies on the synthesis of 2-(2-amino-3-carboxypropyl)-isoxazolin-5-one in Lathyrus odoratus seedings [proceedings].
Topics: Amino Acids; Isoxazoles; Methionine; Plants; S-Adenosylmethionine | 1977 |
Methionine transport in Pseudomonas aeruginosa.
Topics: Adenosine Triphosphate; Arsenates; Biological Transport, Active; Citrates; Glucose; Methionine; Mutation; Pseudomonas aeruginosa; S-Adenosylmethionine; Species Specificity; Stereoisomerism; Temperature | 1979 |
Regulation of methionine biosythesis in Neurospora crassa.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Cell Division; Choline; Enzyme Activation; Glycine Hydroxymethyltransferase; Methionine; Mutation; Neurospora; Neurospora crassa; S-Adenosylmethionine; Tetrahydrofolate Dehydrogenase | 1975 |
Letter: Methylation of mitochondrial RNA species in the wild-type and poky strains of Neurospora crassa.
Topics: Chromatography, DEAE-Cellulose; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Methionine; Methyltransferases; Mitochondria; Mutation; Neurospora; Neurospora crassa; RNA; S-Adenosylmethionine; Species Specificity | 1975 |
Sulfate uptake in Saccharomyces cerevisiae: biochemical and genetic study.
Topics: Chromates; Enzyme Repression; Genes; Membrane Transport Proteins; Methionine; Mutation; Nucleotidyltransferases; Oxidoreductases; Phosphotransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Selenium; Sulfates | 1977 |
Stereochemical studies of enzymic C-methylations.
Topics: Enzymes; Magnetic Resonance Spectroscopy; Methionine; Methylation; S-Adenosylmethionine; Stereoisomerism; Structure-Activity Relationship; Vitamin B 12 | 1977 |
Lack of enhancement of dimethyltryptamine formation in rat brain and rabbit lung in vivo by methionine or S-adenosylmethionine.
Topics: Animals; Brain; Lung; Male; Methionine; N,N-Dimethyltryptamine; Rabbits; Rats; S-Adenosylmethionine; Tryptamines | 1978 |
Methionyl-transfer ribonucleic acid deficiency during G1 arrest of Saccharomyces cerevisiae.
Topics: Amino Acyl-tRNA Synthetases; Cell Division; Crosses, Genetic; Genes; Methionine; Methionine-tRNA Ligase; Mutation; Phenotype; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Temperature | 1977 |
Function of S-adenosylmethionine in germinating yeast ascospores.
Topics: Adenine; Adenosylmethionine Decarboxylase; Fungal Proteins; Leucine; Methionine; Methionine Adenosyltransferase; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Species Specificity; Spores, Fungal; tRNA Methyltransferases | 1977 |
L-methionine as an ethylene precursor in Saccharomyces cerevisiae.
Topics: Drug Synergism; Ethionine; Ethylenes; Glucose; Methionine; Pyruvates; S-Adenosylmethionine; Saccharomyces cerevisiae | 1977 |
S-adenosyl methionine requiring mutants in Saccharomyces cerevisiae: evidences for the existence of two methionine adenosyl transferases.
Topics: Bicarbonates; Culture Media; Enzyme Activation; Genes; Genetic Linkage; Methionine; Methionine Adenosyltransferase; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae; Transferases | 1978 |
Properties and biosynthesis of cyclopropane fatty acids in Escherichia coli.
Topics: Coliphages; Escherichia coli; Fatty Acids; Genes; Methionine; Mutation; Phospholipids; S-Adenosylmethionine | 1979 |
Methylation hypothesis.
Topics: Adult; Animals; Brain; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Liver; Lung; Male; Methionine; Methylation; Mice; Rabbits; Rats; S-Adenosylmethionine; Tryptamines | 1979 |
Synthesis and accumulation of polyamines and S-adenosylmethionine in Chinese cabbage infected by turnip yellow mosaic virus.
Topics: Kinetics; Methionine; Mosaic Viruses; Plants; Putrescine; S-Adenosylmethionine; Spermidine; Spermine | 1979 |
Post-translational modification of actins synthesized in vitro.
Topics: Acetyl Coenzyme A; Acetylation; Actins; Animals; Cell Line; Methionine; Methylation; Muscles; Protein Biosynthesis; S-Adenosylmethionine | 1979 |
De novo synthesis of methionine in normal and Brugia-infected Aedes aegypti.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aedes; Animals; Brugia; Cell-Free System; Female; Filarioidea; Homocysteine; Male; Methionine; Molecular Weight; S-Adenosylmethionine; Tetrahydrofolates; Tissue Extracts; Vitamin B 12 | 1979 |
The importance of non-skeletal muscle sources of urinary 3-methyl-histidine in the rat.
Topics: Animals; Histidine; Methionine; Methylhistidines; Muscle Proteins; Muscles; Rats; S-Adenosylmethionine | 1979 |
Inhibition of immune cell function by adenosine: biochemical studies.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Animals; Cytotoxicity, Immunologic; Homocysteine; Imidazoles; Lymphocytes; Methionine; Mice; S-Adenosylmethionine; Theophylline; Uridine | 1979 |
Biosynthesis of adenosyl-D-methionine and adenosyl-2-methylmethionine by Candida utilis.
Topics: Candida; Cell-Free System; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine; Stereoisomerism; Substrate Specificity | 1978 |
Tissue distribution of S-adenosylmethionine and S-adenosylhomocysteine in the rat. Effect of age, sex and methionine administration on the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines.
Topics: Age Factors; Animals; Brain; Glycine; Homocysteine; Hydrolases; Kidney; Liver; Methionine; Methionine Adenosyltransferase; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 1977 |
S-adenosylmethionine metabolism and its relation to polyamine synthesis in rat liver. Effect of nutritional state, adrenal function, some drugs and partial hepatectomy.
Topics: Adenosylmethionine Decarboxylase; Adrenalectomy; Animals; Female; Hepatectomy; Hydrocortisone; Liver; Methionine; Mitoguazone; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Starvation; Thioacetamide | 1977 |
The role of transamination in methionine oxidation in the rat.
Topics: Amino Acids, Sulfur; Aminooxyacetic Acid; Animals; Keto Acids; Liver; Male; Methionine; Oxidation-Reduction; Phenylhydrazines; Rats; S-Adenosylmethionine; Tissue Distribution; Transaminases | 1978 |
Uptake of adenosylmethionine and related sulfur compounds by isolated rat liver.
Topics: Biological Transport; Dinitrophenols; Fatty Liver; Kinetics; Liver; Methionine; S-Adenosylmethionine | 1978 |
Selection and preliminary characterization of cycloleucine-resistant CHO cells affected in methionine metabolism.
Topics: Amino Acids; Cell Line; Clone Cells; Cycloleucine; Drug Resistance; Methionine; Methionine Adenosyltransferase; Mutation; Protein Biosynthesis; S-Adenosylmethionine; Transcription, Genetic; Transferases | 1978 |
Effects of exogenous L-dopa on the metabolism of methionine and S-adenosylmethionine in the brain.
Topics: Animals; Brain; Levodopa; Methionine; Methylation; Rats; S-Adenosylmethionine | 1978 |
Autoregulation of phospholipid N-methylation by the membrane phosphatidylethanolamine content.
Topics: Animals; Cells, Cultured; Ethanolamines; Liver; Membrane Lipids; Methionine; Methylation; Methyltransferases; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine | 1978 |
Methionine metabolism in BHK cells: preliminary characterization of the physiological effects of cycloleucine, an inhibitor of s-adenosylmethionine biosynthesis.
Topics: Amino Acids; Cell Cycle; Cell Division; Cell Line; Cycloleucine; DNA; Dose-Response Relationship, Drug; Methionine; Methylation; Protein Biosynthesis; RNA; S-Adenosylmethionine | 1978 |
Effect of methionine-loading on methyl group synthesis and activation in rat brain and liver.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Glycine Hydroxymethyltransferase; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Rats; S-Adenosylmethionine | 1978 |
[Incorporation of S-adenosylmethionine in the isolated and perfused rat liver. Preliminary study].
Topics: Animals; Liver; Methionine; Rats; S-Adenosylmethionine | 1978 |
Regulation of methionine synthesis in Saccharomyces cerevisiae operates through independent signals: methionyl-tRNAmet and S-adenosylmethionine.
Topics: Cycloheximide; Enzyme Repression; Lyases; Methionine; Methionine-tRNA Ligase; Mutation; Nucleotidyltransferases; Phenazines; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Temperature; Transcription, Genetic | 1976 |
Biosynthesis of ribosylthymine in the transfer RNA of Streptococcus faecalis: a folate-dependent methylation not involving S-adenosylmethionine.
Topics: Enterococcus faecalis; Folic Acid; Formates; Methionine; Methylation; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Thymine | 1975 |
Biosynthetic pathway of ribothymidine in B. subtilis and M. lysodeikticus involving different coenzymes for transfer RNA and ribosomal RNA.
Topics: Adenosine; Bacillus subtilis; Borohydrides; Coenzymes; Escherichia coli; Methionine; Methylation; Methylguanidine; Micrococcus; Ribonucleosides; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Tetrahydrofolates; Uridine | 1975 |
Compartmentation of the amino acid pool in Saccharomycopsis lipolytica.
Topics: Amino Acids; Ascomycota; Cytoplasm; Methionine; Mutation; S-Adenosylmethionine; Saccharomycopsis; Vacuoles | 1977 |
A methionine-reversible folate deficiency in rats following the acute administration of diethylnitrosamine and alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Animals; Choline; Diet; Diethylnitrosamine; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Liver; Male; Methionine; Nitrosamines; Rats; S-Adenosylmethionine; Thiocyanates; Time Factors | 1977 |
Methionine metabolism in BHK cells: the regulation of methionine adenosyltransferase.
Topics: Adenosine Monophosphate; Cell Cycle; Clone Cells; Cycloheximide; Cycloleucine; Dactinomycin; Enzyme Induction; Enzyme Repression; Erythromycin; Genes, Regulator; Methionine; Methionine Adenosyltransferase; Methionine-tRNA Ligase; Puromycin; RNA, Transfer; S-Adenosylmethionine; Transferases | 1977 |
Formation of methionine from alpha-amino-n-butyric acid and 5'-methylthioadenosine in the rat.
Topics: Adenosine; Aminobutyrates; Animals; Body Weight; Butyrates; Choline; Cysteine; Deoxyadenosines; Homoserine; Male; Methionine; Rats; S-Adenosylmethionine; Thionucleosides | 1977 |
Determination of the absolute configuration at the sulfonium center of S-adenosylmethionine. Correlation with the absolute configuration of the diastereomeric S-carboxymethyl-(S)-methionine salts.
Topics: Crystallography; Methionine; Molecular Conformation; S-Adenosylmethionine; Sulfonium Compounds | 1977 |
The influence of DL-methionine on the metabolism of S-adenosylethionine in rats chronically treated with DL-ethionine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Body Weight; Circadian Rhythm; Ethionine; Feeding Behavior; Female; Liver; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
Studies on metabolic role of 5'-Methylthioadenosine in Ochromonas malhamensis and other microorganisms.
Topics: Adenosine; Cell Membrane Permeability; Eukaryota; Methionine; N-Glycosyl Hydrolases; Ribose; S-Adenosylmethionine; Vitamin B 12 | 1976 |
Methionine overproduction by Saccharomycopsis lipolytica.
Topics: Ascomycota; Carbon-Sulfur Lyases; Cystine; Drug Resistance, Microbial; Enzyme Repression; Ethionine; Glutathione; Lyases; Methionine; Mutation; S-Adenosylmethionine; Saccharomycopsis; Selenomethionine | 1976 |
Evidence for S-adenosylmethionine independent catabolism of methionine in the rat.
Topics: Animals; Carbon Dioxide; Cysteine; Formaldehyde; Formates; Glycine; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Serine | 1976 |
Assay and regulation of S-adenosylmethionine synthetase in Saccharomyces cerevisiae and Candida utilis.
Topics: Adenosine Triphosphate; Candida; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Enzyme Repression; Methionine; Phosphates; S-Adenosylmethionine; Saccharomyces cerevisiae; Threonine; Transferases | 1975 |
Existence of two levels of repression in the biosynthesis of methionine in Saccharomyces cerevisiae: effect of lomofungin on enzyme synthesis.
Topics: Antifungal Agents; Cycloheximide; Enzyme Repression; Fungal Proteins; Homocysteine; Homoserine; Lyases; Methionine; Phenazines; RNA; RNA, Messenger; S-Adenosylmethionine; Saccharomyces cerevisiae | 1975 |
Biochemical and regulatory effects of methionine analogues in Saccharomyces cerevisiae.
Topics: Enzyme Repression; Ethionine; Fungal Proteins; Kinetics; Methionine; Methionine Adenosyltransferase; Methionine-tRNA Ligase; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Selenium; Selenomethionine; Sulfonium Compounds; Sulfur Radioisotopes | 1975 |
tRNAs undermethylation in a met-regulatory mutant of Saccharomyces cerevisiae.
Topics: Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Repression; Haploidy; Methionine; Methylation; Mutation; Nucleotides; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Tritium; tRNA Methyltransferases | 1975 |
Methionine-and S-adenosyl methionine-mediated repression in a methionyl-transfer ribonucleic-acid synthetase mutant of Saccharomyces cerevisiae.
Topics: Amino Acyl-tRNA Synthetases; Crosses, Genetic; Enzyme Repression; Genes; Kinetics; Methionine; Methionine-tRNA Ligase; Mutation; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Temperature | 1975 |
Evidence for an S-adenosylmethionine requirement in the chemotactic behavior of Salmonella typhimurium.
Topics: Arsenates; Chemotaxis; Chloramphenicol; Cycloleucine; Methionine; Methionine Adenosyltransferase; Mutation; Protein Biosynthesis; S-Adenosylmethionine; Salmonella typhimurium; Species Specificity | 1975 |
Role of methionine in bacterial chemotaxis: requirement for tumbling and involvement in information processing.
Topics: Arsenates; Chemotaxis; Escherichia coli; Methionine; Mutation; S-Adenosylmethionine | 1975 |
Effect of methionine and methionine sulphoximine on rat brain S-adenosyl methionine levels.
Topics: Animals; Brain; Male; Methionine; Methionine Sulfoximine; Organ Specificity; Rats; S-Adenosylmethionine | 1975 |
Purification and properties of homoserine transacetylase from Bacillus polymyxa.
Topics: Acetyl Coenzyme A; Acetyltransferases; Allosteric Regulation; Bacillus; Chromatography, Gel; Chromatography, Ion Exchange; Drug Stability; Electrophoresis, Polyacrylamide Gel; Half-Life; Homoserine; Kinetics; Methionine; Molecular Weight; S-Adenosylmethionine; Temperature; Time Factors; Zinc | 1975 |
Regulation of homoserine transacetylase in whole cells of Bacillus polymyxa.
Topics: Acetyltransferases; Bacillus; Cell Division; Culture Media; Drug Stability; Homoserine; Kinetics; Methionine; S-Adenosylmethionine; Temperature; Time Factors; Toluene | 1975 |
The elevation of cerebral histamine-N-and catechol-O-methyl transferase activities by L-methionine-dl-sulfoximine.
Topics: Animals; Basal Ganglia; Brain; Brain Stem; Catechol O-Methyltransferase; Cerebellum; Cerebral Cortex; Guinea Pigs; Hippocampus; Histamine N-Methyltransferase; Hypothalamus; Kinetics; Male; Mesencephalon; Methionine; Methionine Sulfoximine; Methylation; Methyltransferases; Mice; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1975 |
Activation of cystathionine synthase by adenosylmethionine and adenosylethionine.
Topics: Adenosine Triphosphate; Animals; Cycloheximide; Cystathionine beta-Synthase; Dactinomycin; Dietary Proteins; Enzyme Activation; Ethionine; Hydro-Lyases; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Time Factors | 1975 |
Methionine transport in Yersinia pestis.
Topics: Amobarbital; Arsenates; Biological Transport, Active; Cell Membrane; Cell-Free System; Cyanides; Cytoplasm; Glucose; Methionine; Methionine Adenosyltransferase; Phenylalanine; S-Adenosylmethionine; Spheroplasts; Sulfhydryl Reagents; Temperature; Uncoupling Agents; Yersinia pestis | 1975 |
The relationships between vitamin B12 and folic acid and the effect of methionine on folate metabolism.
Topics: Animals; Biological Transport; Diet; Folic Acid; Formiminoglutamic Acid; Histidine; Liver; Male; Methionine; Perfusion; Rats; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1975 |
The effect of ethionine on ribonucleic acid synthesis in rat liver.
Topics: Adenosine Triphosphate; Animals; Cycloheximide; Ethionine; Female; HeLa Cells; Inosine; Liver; Liver Neoplasms; Methionine; Methylation; Mitoguazone; Rats; RNA; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine | 1975 |
Folate deficiency in the livers of diethylnitrosaminetreated rats.
Topics: Animals; Diethylnitrosamine; Folic Acid Deficiency; Glutamates; In Vitro Techniques; Liver; Male; Methionine; Methylation; Nitrosamines; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1976 |
Effect of nitrous oxide and methionine on hepatic S-adenosylmethionine levels and in vivo histidine oxidation in rats.
Topics: Animals; Histidine; Kinetics; Liver; Male; Methionine; Nitrous Oxide; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1992 |
Biosynthesis of sulphur amino acids in Saccharomyces cerevisiae: regulatory roles of methionine and S-adenosylmethionine reassessed.
Topics: Amino Acids, Sulfur; Carbon-Oxygen Lyases; Cysteine Synthase; Enzyme Repression; Gene Expression Regulation, Fungal; Lyases; Methionine; Multienzyme Complexes; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1992 |
Ergosterol levels in two L-methionine-enriched mutants of the methylotrophic yeast Candida boidinii ICCF26.
Topics: Candida; Cysteine; Ergosterol; Methionine; Mutagenesis; S-Adenosylmethionine | 1992 |
Activation of the anaerobic ribonucleotide reductase from Escherichia coli by S-adenosylmethionine.
Topics: Anaerobiosis; Cytidine Triphosphate; Deoxyadenosines; Enzyme Activation; Escherichia coli; Kinetics; Methionine; Models, Biological; Oxidation-Reduction; Ribonucleotide Reductases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1992 |
Physiological analysis of mutants of Saccharomyces cerevisiae impaired in sulphate assimilation.
Topics: Cysteine; Genes, Fungal; Homocysteine; Methionine; Mutation; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfates; Sulfides; Sulfites; Thiosulfates | 1992 |
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression.
Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1992 |
Prolonged acetaminophen ingestion by mice fed a methionine-limited diet does not affect iron-induced liver lipid peroxidation or S-adenosylmethionine.
Topics: Acetaminophen; Animals; Cysteine; Glutathione; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Male; Methionine; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Superoxide Dismutase | 1992 |
Cloning, nucleotide sequence, and regulation of MET14, the gene encoding the APS kinase of Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Base Sequence; beta-Galactosidase; Blotting, Northern; Cloning, Molecular; Codon; DNA Mutational Analysis; Gene Expression Regulation, Fungal; Methionine; Molecular Sequence Data; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfur; Transcription, Genetic | 1991 |
Metabolism, cellular actions, and cytotoxicity of selenomethionine in cultured cells.
Topics: Animals; Cell Line; Cell Survival; DNA Replication; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Methionine; Methionine Adenosyltransferase; Methylation; Models, Biological; Neoplasm Proteins; RNA, Neoplasm; S-Adenosylmethionine; Selenomethionine | 1991 |
Exogenous gangliosides may affect methylation mechanisms in neuronal cell cultures.
Topics: Animals; Brain; Cells, Cultured; Chemical Precipitation; Chick Embryo; Choline; DNA; Ethanolamine; Ethanolamines; Gangliosides; Methionine; Methylation; Molecular Weight; Neurons; Phospholipids; RNA; S-Adenosylmethionine; Sulfur Radioisotopes; Trichloroacetic Acid; Tritium | 1991 |
S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mortality; S-Adenosylmethionine | 1992 |
Phytohormonal regulation of S-adenosylmethionine synthetase and S-adenosylmethionine levels in dwarf pea epicotyls.
Topics: Abscisic Acid; Cycloheximide; Fabaceae; Gibberellins; Isoenzymes; Methionine; Methionine Adenosyltransferase; Plants; Plants, Medicinal; S-Adenosylmethionine | 1991 |
13-cis-retinoic acid alters methionine metabolism in rats.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Isotretinoin; Liver; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sulfur | 1991 |
Central-nervous-system methyl-group metabolism in children with neurological complications of HIV infection.
Topics: Biopterins; Child, Preschool; Encephalitis; HIV Seropositivity; Humans; Infant; Methionine; Methylation; Neopterin; S-Adenosylmethionine; Tetrahydrofolates | 1990 |
Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression Regulation, Fungal; Genes, Fungal; Genotype; Glucosephosphate Dehydrogenase; Glutathione; Homocysteine; Humans; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis; Phenotype; Restriction Mapping; S-Adenosylmethionine; Saccharomyces cerevisiae; Sequence Homology, Nucleic Acid; Transcription, Genetic | 1991 |
Disruption of thymidylate synthesis and glycine-serine interconversion by L-methionine and L-homocystine in Raji cells.
Topics: Amino Acids; Burkitt Lymphoma; Glycine; Glycine Hydroxymethyltransferase; Homocystine; Humans; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1990 |
Protective effects of S-adenosyl-L-methionine against enzyme leakage from cultured hepatocytes and hypotonic hemolysis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cells, Cultured; Hemolysis; Hypotonic Solutions; L-Lactate Dehydrogenase; Liver; Male; Methionine; Ornithine Carbamoyltransferase; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase | 1990 |
Activation of lysine 2,3-aminomutase by S-adenosylmethionine.
Topics: Amino Acid Isomerases; Clostridium; Deoxyadenosines; Enzyme Activation; Intramolecular Transferases; Methionine; S-Adenosylmethionine | 1990 |
S-adenosylmethionine and S-adenosylhomocysteine transitions in encysting Physarum flavicomum amoebae.
Topics: Chromatography, High Pressure Liquid; Methionine; Physarum; S-Adenosylhomocysteine; S-Adenosylmethionine | 1990 |
Cerebrospinal fluid concentrations of S-adenosylmethionine, methionine, and 5-methyltetrahydrofolate in a reference population: cerebrospinal fluid S-adenosylmethionine declines with age in humans.
Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Methionine; S-Adenosylmethionine; Tetrahydrofolates | 1990 |
Reversion to a homocysteine-responsive phenotype in a human melanoma cell line is associated with diminished growth potential and increased methionine biosynthesis.
Topics: Adenosine; Cell Division; Culture Media; Deoxyadenosines; Homocysteine; Humans; Melanoma, Experimental; Methionine; Phenotype; S-Adenosylmethionine; Tetrahydrofolates; Thionucleosides; Tumor Cells, Cultured | 1990 |
Protective effect of S-adenosyl-L-methionine against CCl4-induced hepatotoxicity in cultured hepatocytes.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Cells, Cultured; Chemical and Drug Induced Liver Injury; Leucine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1990 |
Cobalamin neuropathy. Is S-adenosylhomocysteine toxicity a factor?
Topics: Animals; Brain Chemistry; Chiroptera; Chromatography, High Pressure Liquid; Homocysteine; Liver; Methionine; Neuromuscular Diseases; S-Adenosylhomocysteine; S-Adenosylmethionine; Valine; Vitamin B 12 Deficiency | 1990 |
Effects of selenomethionine on cell growth and on S-adenosylmethionine metabolism in cultured malignant cells.
Topics: Cell Division; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Nucleotides; S-Adenosylmethionine; Selenium; Selenomethionine; Tumor Cells, Cultured | 1990 |
Biosynthesis of methanopterin.
Topics: Aniline Compounds; Biopterins; Euryarchaeota; Methionine; Methylation; Neopterin; Organophosphorus Compounds; Pterins; S-Adenosylmethionine | 1990 |
Adaptation of adenosylmethionine metabolism and methionine recycling to variations in dietary methionine in the rat.
Topics: Adaptation, Physiological; Animals; Diet; Half-Life; Liver; Methionine; Muscles; Rats; S-Adenosylmethionine | 1990 |
L-3,4-dihydroxyphenylalanine (levodopa) lowers central nervous system S-adenosylmethionine concentrations in humans.
Topics: Adolescent; Akinetic Mutism; Biopterins; Child, Preschool; Humans; Infant; Levodopa; Methionine; NADH, NADPH Oxidoreductases; Phenylketonurias; Pyridoxine; S-Adenosylmethionine; Tetrahydrofolates; Tyrosine | 1990 |
The role of cap methylation in the translational activation of stored maternal histone mRNA in sea urchin embryos.
Topics: Animals; Aphidicolin; Cell Nucleus; Dactinomycin; Diterpenes; Embryo, Nonmammalian; Female; Fertilization; Histones; Methionine; Methylation; Ovum; Protein Biosynthesis; RNA; RNA Caps; RNA, Messenger; S-Adenosylmethionine; Sea Urchins; tRNA Methyltransferases; Zygote | 1985 |
IgE-dependent activation of mast cells is not associated with enhanced phospholipid methylation.
Topics: Animals; Cyclic AMP; Histamine Release; Homocysteine; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Methionine; Methylation; Phosphatidylserines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tritium; Tubercidin | 1986 |
Biochemical analysis of the role of transmethylation in the methionine dependence of tumor cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biogenic Polyamines; Cell Division; Culture Media; Cystathionine beta-Synthase; Homocysteine; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Phenotype; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1989 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
The nature of the defect in cobalamin G mutation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Cell Division; Cells, Cultured; Female; Fibroblasts; Humans; Infant; Male; Methionine; Mutation; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1989 |
Inhibition by ethanol of rat liver plasma membrane (Na+,K+)ATPase: protective effect of S-adenosyl-L-methionine, L-methionine, and N-acetylcysteine.
Topics: Acetaldehyde; Acetylcysteine; Animals; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Ethanol; Female; Glutathione; Liver; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase | 1989 |
Agarose-selected variants of two human tumor cell lines exhibit altered methionine auxotrophy.
Topics: Cell Line; Cell Transformation, Neoplastic; Genetic Variation; Homocysteine; Humans; Melanoma; Methionine; Neuroblastoma; Nucleic Acids; S-Adenosylmethionine; Sepharose; Tumor Cells, Cultured | 1989 |
SVLM21, a Sindbis virus mutant resistant to methionine deprivation, encodes an altered methyltransferase.
Topics: Animals; Cell Line; Cells, Cultured; Chromatography, Thin Layer; Guanylyl Imidodiphosphate; Kinetics; Methionine; Methylation; Mutation; S-Adenosylmethionine; Sindbis Virus; Temperature; tRNA Methyltransferases; Virus Replication | 1989 |
Effect of toluene on rat synaptosomal phospholipid methylation and membrane fluidity.
Topics: Animals; Brain; Male; Membrane Fluidity; Methionine; Methionine Adenosyltransferase; Methylation; Norepinephrine; Phosphatidylethanolamines; Phospholipids; Propranolol; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Synaptosomes; Toluene | 1989 |
The Escherichia coli regulatory protein MetJ binds to a tandemly repeated 8 bp palindrome.
Topics: Base Sequence; Deoxyribonucleases; DNA, Bacterial; Escherichia coli; Methionine; Molecular Sequence Data; Mutation; Operator Regions, Genetic; Repetitive Sequences, Nucleic Acid; Repressor Proteins; S-Adenosylmethionine; Transcription Factors | 1989 |
Effect of dietary methyl group deficiency on one-carbon metabolism in rats.
Topics: Amino Acids; Animals; Carbon; Choline Deficiency; Diet; Glycine N-Methyltransferase; Liver; Male; Methionine; Methylation; Methyltransferases; Organ Size; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Weight Gain | 1989 |
Regulation of 5-methyltetrahydrofolate synthesis.
Topics: Animals; Liver; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1989 |
Short term effect of nitrous oxide on methionine and S-adenosyl methionine concentrations.
Topics: Animals; Brain Chemistry; Liver; Male; Methionine; Nitrous Oxide; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Time Factors | 1989 |
Oxidation of 5-methyltetrahydrofolate in cobalamin-inactivated rats.
Topics: Animals; Formyltetrahydrofolates; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 | 1989 |
Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver.
Topics: Animals; Choline Deficiency; Liver; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1989 |
Regulation of S-adenosyl methionine synthesis in the mouse embryo.
Topics: Animals; Binding, Competitive; Blastocyst; Embryo, Mammalian; Ethionine; Homocysteine; Humans; Methionine; Methylation; Mice; Mice, Inbred Strains; Morula; Oocytes; S-Adenosylmethionine | 1989 |
Partial purification and properties of the isozymes of S-adenosylmethionine synthetase from sheep liver.
Topics: Animals; Chromatography; Dimethyl Sulfoxide; Enzyme Activation; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Liver; Methionine; Methionine Adenosyltransferase; Molecular Weight; S-Adenosylmethionine; Sheep; Transferases | 1989 |
Effects of dietary polyamine precursors on the metabolism and tissue concentrations of amino acids in the rat.
Topics: Adenosine; Amino Acids; Animals; Arginine; Biogenic Polyamines; Deoxyadenosines; Diet; Liver; Male; Methionine; Muscles; Ornithine; Rats; Rats, Inbred Strains; RNA, Transfer, Amino Acid-Specific; S-Adenosylmethionine; Thionucleosides | 1989 |
Effects of nitrous oxide inactivation of vitamin B12 and of methionine on folate coenzyme metabolism in rat liver, kidney, brain, small intestine and bone marrow.
Topics: Animals; Bone Marrow; Brain; Folic Acid; Intestine, Small; Kidney; Liver; Male; Methionine; Nitrous Oxide; Organ Specificity; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1989 |
Perturbation of methionine metabolism in sheep with nitrous-oxide-induced inactivation of cobalamin.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Brain; Formiminoglutamic Acid; Homocystine; Liver; Male; Methionine; Methylmalonyl-CoA Mutase; Methyltransferases; Myocardium; Nitrous Oxide; Orchiectomy; S-Adenosylmethionine; Sheep; Vitamin B 12 | 1986 |
The influence of nitrous oxide on methionine, S-adenosylmethionine, and other amino acids.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Brain; Glutathione; Liver; Male; Methionine; Methylmalonyl-CoA Mutase; Nitrous Oxide; Rats; S-Adenosylmethionine; Vitamin B 12 Deficiency | 1986 |
Altered methionine metabolism in metastatic variants of a human melanoma cell line.
Topics: Cell Division; Culture Media; Homocysteine; Humans; Melanoma; Methionine; Neoplasm Metastasis; S-Adenosylmethionine; Tumor Cells, Cultured; Vitamin B 12 | 1989 |
Evidence for altered methionine methyl-group utilization in the diabetic rat's brain.
Topics: Administration, Oral; Animals; Brain; Caseins; Diabetes Mellitus, Experimental; Diet; Female; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptozocin; Time Factors | 1988 |
Decreased methylation rates of DNA in SV40-transformed human fibroblasts.
Topics: Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Methionine; Methylation; S-Adenosylmethionine; Simian virus 40 | 1986 |
Down-regulation of rat liver beta-adrenergic receptors by cysteine.
Topics: Animals; Cysteine; Diet; Liver; Methionine; Methionine Adenosyltransferase; Myocardium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; S-Adenosylmethionine | 1986 |
Biosynthesis of methylphosphomannosyl residues in the oligosaccharides of Dictyostelium discoideum glycoproteins. Evidence that the methyl group is derived from methionine.
Topics: Amidohydrolases; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dictyostelium; Glycoproteins; Glycoside Hydrolases; Hexosephosphates; Hydrogen-Ion Concentration; Kinetics; Mannosephosphates; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Methionine; Methylation; Oligosaccharides; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Phosphorylation; S-Adenosylmethionine | 1986 |
Methionine metabolism in mammals. Adaptation to methionine excess.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Glutathione; Liver; Male; Methionine; Methionine Adenosyltransferase; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine | 1986 |
An ethA mutation in Bacillus subtilis 168 permits induction of sporulation by ethionine and increases DNA modification of bacteriophage phi 105.
Topics: Adenosine; Bacillus subtilis; Bacteriophages; DNA, Viral; Ethionine; Methionine; Methylation; Mutation; S-Adenosylmethionine; Spores, Bacterial | 1986 |
Effect of dietary cystine on methionine metabolism in rat liver.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cystine; Dietary Proteins; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serine | 1986 |
Interactions of the Escherichia coli methionine repressor with the metF operator and with its corepressor, S-adenosylmethionine.
Topics: beta-Galactosidase; Escherichia coli; Genes; Genes, Bacterial; Genes, Regulator; Methionine; Nucleic Acid Hybridization; Plasmids; Repressor Proteins; S-Adenosylmethionine; Transcription Factors | 1986 |
S-adenosylmethionine and transmethylation reactions in trichomonads.
Topics: Animals; Chromatography, High Pressure Liquid; Crithidia; Eukaryota; Leishmania; Leishmania mexicana; Methionine; Methylation; S-Adenosylmethionine; Trichomonas vaginalis; Tritrichomonas; Trypanosomatina | 1987 |
Effect of dietary methionine, arginine and ornithine on the metabolism and accumulation of polyamines, S-adenosylmethionine and macromolecules in rat liver and skeletal muscle.
Topics: Amino Acids; Animals; Arginine; Body Weight; Diet; Eflornithine; Liver; Macromolecular Substances; Methionine; Muscles; Ornithine; Polyamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1987 |
The role of formate and S-adenosylmethionine in the reversal of nitrous oxide inhibition of formate oxidation in the rat.
Topics: Adenosine; Animals; Carbon Dioxide; Ethionine; Formates; Liver; Methionine; Nitrous Oxide; Oxidation-Reduction; Rats; S-Adenosylmethionine | 1987 |
Carboxylmethylation of calmodulin in cultured pituitary cells.
Topics: Calcium; Calmodulin; Cell Line; Chemical Fractionation; Chromatography, High Pressure Liquid; Cycloheximide; Cytosol; Egtazic Acid; Kinetics; Methionine; Methionine Adenosyltransferase; Methylation; Pituitary Gland; S-Adenosylmethionine | 1987 |
Rates of oxidation of the methionine and S-adenosylmethionine methyl carbons in isolated rat hepatocytes.
Topics: Animals; Carbon Dioxide; Kinetics; Liver; Male; Methionine; Methylation; Oxidation-Reduction; Rats; S-Adenosylmethionine | 1987 |
S-adenosylmethionine synthetase in the thermophilic archaebacterium Sulfolobus solfataricus. Purification and characterization of two isoforms.
Topics: Adenosine Triphosphate; Archaea; Bacteria; Chromatography; Cytosol; Drug Stability; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Magnesium; Methionine; Methionine Adenosyltransferase; Molecular Weight; S-Adenosylmethionine; Transferases | 1988 |
In vivo oxidation of the methyl group of hepatic 5-methyltetrahydrofolate.
Topics: Adenosine; Animals; Betaine; Carbon Dioxide; Deoxyadenosines; Formyltetrahydrofolates; Glycine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thionucleosides; Time Factors | 1988 |
Methylthioadenosine toxicity and metabolism to methionine in mammalian cells.
Topics: Adenosine; Cell Division; Cell Line; Deoxyadenosines; Humans; Intracellular Fluid; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine; Thionucleosides; Tumor Cells, Cultured | 1988 |
Tumor uptake studies of S-adenosyl-L-[methyl-11C]methionine and L-[methyl-11C]methionine.
Topics: Animals; Carbon Radioisotopes; Methionine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Rats; S-Adenosylmethionine; Tissue Distribution; Tomography, Emission-Computed | 1988 |
Phosphatidylcholine synthesis in yeast.
Topics: Choline; Cytidine Diphosphate Choline; Ethionine; Methionine; Methylation; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae | 1988 |
S-adenosylmethionine may not be essential for signal transduction during bacterial chemotaxis.
Topics: Bacterial Proteins; Chemotaxis; Membrane Proteins; Methionine; Methyl-Accepting Chemotaxis Proteins; S-Adenosylmethionine; Salmonella typhimurium | 1987 |
S-adenosylmethionine and its sulfur metabolites.
Topics: Cell Line; Chromatography, High Pressure Liquid; HeLa Cells; Humans; Indicators and Reagents; Methionine; Radioisotope Dilution Technique; S-Adenosylmethionine; Sulfur Radioisotopes | 1987 |
Growth support and toxicity of homocysteine and its effects on methionine metabolism in non-transformed and chemically transformed C3H/10T1/2 cells.
Topics: Animals; Cell Division; Cell Line; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Homocystine; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1988 |
S-adenosyl-L-methionine protects the hippocampal CA1 neurons from the ischemic neuronal death in rat.
Topics: Animals; Cell Membrane; Cell Survival; Cytidine Diphosphate Choline; Hippocampus; Ischemic Attack, Transient; Male; Methionine; Methylation; Necrosis; Nerve Degeneration; Neurons; Phosphatidylcholines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
Methanol production by Mycobacterium smegmatis.
Topics: Mannosides; Methanol; Methionine; Mycobacterium; Polysaccharides; S-Adenosylmethionine | 1988 |
Demyelination and decreased S-adenosylmethionine in 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Biogenic Amines; Biopterins; Child, Preschool; Female; Folic Acid; Humans; Infant; Infant, Newborn; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Myelin Sheath; Oxidoreductases; S-Adenosylmethionine | 1988 |
SVLM21, a mutant of Sindbis virus able to grow in Aedes albopictus cells in the absence of methionine, shows increased sensitivity to S-adenosylhomocysteine hydrolase inhibitors such as neplanocin A.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Aedes; Animals; Antiviral Agents; Cell Line; Genes, Viral; Hydrolases; Methionine; Methyltransferases; Mutation; S-Adenosylmethionine; Sindbis Virus; Tubercidin; Viral Plaque Assay | 1988 |
Methionine metabolism in mammals. The methionine-sparing effect of cystine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cystathionine; Cystathionine beta-Synthase; Cystine; Diet; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1988 |
Clinical correlations of one-carbon metabolism abnormalities.
Topics: Bipolar Disorder; Depressive Disorder; Erythrocytes; Humans; Methionine; Methionine Adenosyltransferase; Psychiatric Status Rating Scales; Psychotropic Drugs; S-Adenosylmethionine; Schizophrenia; Transferases | 1988 |
Biosynthesis of mevinolin, a hypocholesterolemic fungal metabolite, in Aspergillus terreus.
Topics: Anticholesteremic Agents; Aspergillus; Butyrates; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Lovastatin; Methionine; Methylation; S-Adenosylmethionine; T-2 Toxin; Tritium | 1987 |
Relative effects of S-adenosylmethionine depletion on nucleic acid methylation and polyamine biosynthesis.
Topics: Aminobutyrates; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Leukemia L1210; Methionine; Methionine Adenosyltransferase; Methylation; Mice; Nucleic Acids; Polyamines; S-Adenosylmethionine | 1987 |
Hepatic DNA methylation and liver tumor formation in male C3H mice fed methionine- and choline-deficient diets.
Topics: Animals; Body Weight; Choline; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Mice; Mice, Inbred C3H; Organ Size; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1986 |
S-adenosylmethionine: studies on chemical and enzymatic synthesis.
Topics: Adenosylhomocysteinase; Enzymes, Immobilized; Hydrolases; Kinetics; Magnetic Resonance Spectroscopy; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 1987 |
Isozyme-specific enzyme inhibitors. 13. S-[5'(R)-[(N-triphosphoamino)methyl]adenosyl]-L-homocysteine, a potent inhibitor of rat methionine adenosyltransferases.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Chemical Phenomena; Chemistry; Homocysteine; Isoenzymes; Kinetics; Methionine; Methionine Adenosyltransferase; Polyphosphates; Rats; S-Adenosylmethionine; Transferases | 1987 |
Effects of prolonged ethanol feeding on methionine metabolism in rat liver.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcoholism; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Kinetics; Liver; Male; Methionine; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1987 |
The role of methionine in carcinogenesis in vivo.
Topics: Animals; Diet; Liver Neoplasms, Experimental; Methionine; Neoplasms, Experimental; S-Adenosylmethionine | 1986 |
Kinetic and electrophoretic analysis of transmethylation reactions in intact Xenopus laevis oocytes.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Kinetics; Methionine; Methylation; Molecular Weight; Oocytes; S-Adenosylmethionine; Xenopus laevis | 1987 |
Molecular composition of the phosphatidylcholines produced by the phospholipid methylation pathway in rat brain in vivo.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Fatty Acids; Male; Methionine; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1987 |
Methionine metabolism in isolated perfused livers from rats fed on zinc-deficient and restricted diets.
Topics: Animals; Butyrates; Cystathionine; Diet; Homocysteine; In Vitro Techniques; Liver; Male; Methionine; Perfusion; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1986 |
Resistance to multiple adenine nucleoside and methionine analogues in mutant murine lymphoma cells with enlarged S-adenosylmethionine pools.
Topics: Adenosine; Animals; Cells, Cultured; Drug Resistance; Homocysteine; Kinetics; Lymphoma; Methionine; Methionine Adenosyltransferase; Mice; Mutation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
Changes in methionine metabolism induced by D-galactosamine in isolated rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Carbon Radioisotopes; Galactosamine; In Vitro Techniques; Liver; Methionine; Methylation; Rats; S-Adenosylmethionine | 1986 |
Purification and properties of rat lens methionine adenosyltransferase.
Topics: Animals; Antibodies; Enzyme Activation; Hydrogen-Ion Concentration; Lens, Crystalline; Magnesium; Manganese; Methionine; Methionine Adenosyltransferase; Phosphates; Potassium; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Transferases | 1986 |
Purification and characterization of some metabolic effects of S-neplanocylmethionine.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Escherichia coli; Kinetics; L Cells; Male; Methionine; Methylation; Methyltransferases; Mice; Rats; S-Adenosylmethionine; Substrate Specificity | 1985 |
Regulation of methionine synthesis in Escherichia coli: effect of metJ gene product and S-adenosylmethionine on the in vitro expression of the metB, metL and metJ genes.
Topics: Bacterial Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation; Genes; Genes, Bacterial; Methionine; Plasmids; Repressor Proteins; S-Adenosylmethionine; Templates, Genetic; Transcription Factors | 1985 |
Effect of short-term administration of nitrous oxide on plasma concentrations of methionine, tryptophan, phenylalanine and S-adenosyl methionine in man.
Topics: Adult; Aged; Amino Acids; Anesthesia, General; Female; Humans; Male; Methionine; Middle Aged; Nitrous Oxide; Phenylalanine; S-Adenosylmethionine; Time Factors; Tryptophan | 1986 |
Determination of in vivo protein binding of homocysteine and its relation to free homocysteine in the liver and other tissues of the rat.
Topics: Adenine; Animals; Dithioerythritol; Half-Life; Homocysteine; Liver; Methionine; Methods; Proteins; Rats; S-Adenosylmethionine; Sulfur; Time Factors; Tissue Distribution | 1986 |
Requirement of methionine for the replication of canine distemper virus in Vero cells.
Topics: Animals; Cell Line; Cycloleucine; Distemper Virus, Canine; Methionine; RNA, Viral; S-Adenosylmethionine; Viral Proteins; Virus Replication | 1985 |
Effect of zinc deficiency on methionine metabolism, methylation reactions and protein synthesis in isolated perfused rat liver.
Topics: Amino Acids, Sulfur; Animals; Chromatography; DNA; In Vitro Techniques; Liver; Male; Methionine; Methylation; Microsomes, Liver; Perfusion; Phospholipids; Protein Biosynthesis; Rats; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1985 |
Levels of S-adenosylmethionine and S-adenosylethionine in four different tissues of male weanling rats during subchronic feeding of DL-ethionine.
Topics: Adenosine; Animals; Ethionine; Kidney; Liver; Male; Methionine; Pancreas; Rats; Rats, Inbred F344; S-Adenosylmethionine; Testis | 1985 |
Incorporation of intracisternally administered L-[methyl-3H]methionine and S-adenosyl-L-[methyl-3H]-methionine into rat brain phospholipids.
Topics: Animals; Brain; Chromatography, Thin Layer; Half-Life; Injections, Intraventricular; Male; Methionine; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Time Factors | 1985 |
Role of S-adenosylmethionine in DNA synthesis and haemopoiesis.
Topics: Bone Marrow; Deoxyuridine; DNA Replication; Hematopoiesis; Humans; Methionine; Nitrous Oxide; S-Adenosylmethionine; Thymidine; Vitamin B 12 | 1985 |
Comparative studies on the methionine synthesis in sheep and rat tissues.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Female; Kidney; Liver; Methionine; Methyltransferases; Muscles; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sheep; Tissue Distribution | 1985 |
Biosynthesis of 1-methyladenine by isolated segments of starfish ovaries.
Topics: Adenine; Animals; Carbon Radioisotopes; Female; In Vitro Techniques; Kinetics; Methionine; Ovary; Ribonucleoproteins; S-Adenosylmethionine; Sexual Maturation; Starfish | 1985 |
Protein carboxyl methylation-demethylation in rat thymocytes.
Topics: Animals; Carbon Radioisotopes; Kinetics; Methanol; Methionine; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Proteins; Rats; S-Adenosylmethionine; Subcellular Fractions; Thymus Gland; Tritium | 1985 |
Methionine metabolism and cancer.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Gene Expression Regulation; Mammals; Methionine; Methylation; Methyltransferases; Models, Biological; Neoplasms; S-Adenosylmethionine | 1985 |
Letter: The activation of pineal hydroxyindole-O-methyltransferase by psychotomimetic drugs.
Topics: Amphetamine; Carbon Radioisotopes; Dopamine; Enzyme Activation; Ergolines; Hallucinogens; Lysergic Acid Diethylamide; Melatonin; Mescaline; Methionine; Methyltransferases; N,N-Dimethyltryptamine; Phenethylamines; Pineal Gland; S-Adenosylmethionine; Serotonin | 1973 |
An interaction between S-adenosyl-L-methionine and pyridoxal 5'-phosphate, and its effect on Saccharomyces cerevisiae.
Topics: Carbon Radioisotopes; Cell Division; Kinetics; Methionine; Ornithine; Pyridoxal Phosphate; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Transaminases; Tyrosine Transaminase | 1973 |
Activation of methionine synthetase by a reduced triphosphopyridine nucleotide-dependent flavoprotein system.
Topics: Bacterial Proteins; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavoproteins; Homoserine; Hydroxyapatites; Kinetics; Lyases; Methionine; Molecular Weight; NADP; Oxidation-Reduction; S-Adenosylmethionine; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Liver; Membranes; Methionine; Methotrexate; Methyltransferases; NAD; NADP; S-Adenosylmethionine; Serum Albumin, Bovine; Sheep; Tetrahydrofolate Dehydrogenase; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Regulation of C metabolism by L-methionine in Saccharomyces cerevisiae.
Topics: Alcohol Oxidoreductases; Biological Assay; Carbon Isotopes; Cells, Cultured; Chromatography, DEAE-Cellulose; Culture Media; Folic Acid; Formates; Lacticaseibacillus casei; Ligases; Methionine; Methylation; Pediococcus; S-Adenosylmethionine; Saccharomyces cerevisiae; Serine; Tetrahydrofolates; Transferases | 1972 |
Role of methionine in biosynthesis of prodigiosin by Serratia marcescens.
Topics: Alanine; Aspartic Acid; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Culture Media; Escherichia coli; Glutamates; Histidine; Methionine; Methyltransferases; Mutation; Prodigiosin; Proline; Pseudomonas aeruginosa; S-Adenosylmethionine; Serine; Serratia marcescens; Stereoisomerism; Tetrahydrofolates | 1973 |
The occurrence of a transmethylation reaction not involving S-adenosylmethionine in the formation of ribothymidine in Bacillus subtilis transfer-RNA.
Topics: Bacillus subtilis; Chromatography, Thin Layer; Methionine; Ribonucleosides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Thymidine; tRNA Methyltransferases | 1974 |
[Influence of S-adenosylmethionine on the methylation of the RNA by dimethylnitrosamine in vivo].
Topics: Adenine; Animals; Body Weight; Carbon Isotopes; Chromatography, Ion Exchange; Female; Guanine; Hydrochloric Acid; Hydrolysis; Injections, Intravenous; Liver; Male; Methionine; Methylation; Mice; Nitrosamines; Nucleosides; Rats; RNA; S-Adenosylmethionine; Spectrophotometry; Tritium | 1970 |
Polyamine synthesis during initial phases of stress-induced cardiac hypertrophy.
Topics: Adaptation, Physiological; Animals; Butylamines; Carboxy-Lyases; Cardiomegaly; Heart Ventricles; Methionine; Myocardium; Organ Size; Ornithine; Polyamines; Pulmonary Artery; Pyridoxal Phosphate; Rabbits; RNA; S-Adenosylmethionine; Spermidine; Spermine; Stress, Physiological | 1971 |
Novel mutation causing derepression of several enzymes of sulfur metabolism in Neurospora crassa.
Topics: Alkaline Phosphatase; Alleles; Autoradiography; Cell-Free System; Choline; Chromatography, Ion Exchange; Chromosome Mapping; Crosses, Genetic; Culture Media; Electrophoresis; Enzyme Repression; Genes; Genetics, Microbial; Homoserine; Hydro-Lyases; Hydrolases; Isocitrates; Lyases; Methionine; Mutation; Neurospora; Neurospora crassa; Pentosyltransferases; S-Adenosylmethionine; Sucrase; Sulfatases; Sulfates; Sulfur; Sulfur Isotopes; Sulfurtransferases; Transferases | 1972 |
[Research on the enzymatic transmethylation of norepinephrine in the axillary bodies of the small dogfish (Scyliorhinus canicula). I. Study of the methyl donor].
Topics: Adenosine Triphosphate; Animals; Carbon; Carbon Isotopes; Chromaffin System; Epinephrine; In Vitro Techniques; Methionine; Methylation; Norepinephrine; S-Adenosylmethionine; Sharks | 1971 |
Isolation and properties of selenomethionine-resistant mutants of Neurospora crassa.
Topics: Biological Transport; Cell Membrane Permeability; Chromosome Mapping; Crosses, Genetic; Drug Resistance, Microbial; Ethionine; Extrachromosomal Inheritance; Genes; Genetic Linkage; Hot Temperature; Hydro-Lyases; L-Serine Dehydratase; Ligases; Methionine; Mutation; Neurospora; Neurospora crassa; S-Adenosylmethionine | 1974 |
Quantitative analysis of S-adenosylmethionine and S-adenosylhomocysteine in animal tissues.
Topics: Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Homocysteine; Hydrolysis; Liver; Methionine; Methods; Nucleosides; Perchlorates; Rabbits; Radioisotope Dilution Technique; Rats; S-Adenosylmethionine | 1971 |
Assay of S-adenosylmethionine in human blood.
Topics: Adenosine; Carbon Isotopes; Chromatography, Ion Exchange; Humans; Methionine; Perchlorates; Radioisotope Dilution Technique; S-Adenosylmethionine; Spectrophotometry | 1971 |
Transfer ribonucleic acid methylases of nucleoli isolated from a rat tumor.
Topics: Ammonium Chloride; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Chromatography, Ion Exchange; Chromatography, Paper; Cytoplasm; Escherichia coli; Kinetics; Liver Neoplasms; Magnesium; Methionine; Methyltransferases; Neoplasms, Experimental; Osmolar Concentration; Polynucleotides; Rats; RNA, Transfer; S-Adenosylmethionine; Structure-Activity Relationship; Subcellular Fractions; Tritium | 1972 |
Choline oxidation and labile methyl groups in normal and choline-deficient rat liver.
Topics: Acetates; Alcohol Oxidoreductases; Aldehydes; Animals; Autoradiography; Betaine; Carbon Isotopes; Choline; Choline Deficiency; Chromatography; Fatty Acids, Nonesterified; Kinetics; Liver; Male; Methionine; Methylation; Mitochondria, Liver; NAD; Oxidoreductases; Phosphatidylcholines; Rats; S-Adenosylmethionine; Serotonin; Subcellular Fractions; Triglycerides; Tritium | 1972 |
[Effect of S-adenosylmethionine (SAM) on platelet aggregation. In vitro and in vivo study].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Methionine; Platelet Adhesiveness; S-Adenosylmethionine; Serotonin | 1972 |
Enzymatic DNA modifications in isolated nuclei from developing sea urchin embryos.
Topics: Adenine; Aminohydrolases; Animals; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Chromatography, Paper; Cytosine; Cytosine Nucleotides; DNA; Electron Transport Complex IV; Formates; Guanine; Hot Temperature; Methionine; Methylation; Methyltransferases; Proteins; S-Adenosylmethionine; Sea Urchins; Thymidine; Thymine; Tritium | 1972 |
Properties and function of the pyruvate-formate-lyase reaction in clostridiae.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aldehyde-Lyases; Butyrates; Carbon Dioxide; Cell-Free System; Cellulose; Charcoal; Clostridium; Cobalt; Coenzyme A; Ferredoxins; Formates; Iron; Keto Acids; Kinetics; Ligases; Lyases; Methionine; Oxidoreductases; Phosphoric Monoester Hydrolases; Potassium; Pyruvates; S-Adenosylmethionine | 1972 |
Coproporphyrinogenase activities in extracts of Rhodopseudomonas spheroides and Chromatium strain D.
Topics: Adenosine Triphosphate; Anaerobiosis; Carbon Isotopes; Carboxy-Lyases; Chromatium; Dinitrophenols; Flavonoids; Hydrogen-Ion Concentration; Magnesium; Methionine; Molecular Weight; NAD; Naphthoquinones; Phenanthrolines; Porphyrins; Rhodobacter sphaeroides; Rhodopseudomonas; S-Adenosylmethionine | 1972 |
Examination of isolated yeast cell vacuoles for active transport.
Topics: Arginine; Biological Transport, Active; Candida; Carbon Radioisotopes; Inclusion Bodies; Lysine; Methionine; Microscopy, Ultraviolet; S-Adenosylmethionine; Stereoisomerism; Uric Acid | 1974 |
Urinary excretion of 5-methyltetrahydrofolate and liver S-adenosylmethionine levels of rats fed a vitamin B 12-deficient diet.
Topics: Animals; Bacteria; Biological Assay; Biological Transport; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Drug Stability; Ethionine; Folic Acid; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Vitamin B12-dependent methionine synthesis in Rhizobium meliloti.
Topics: Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Dithiothreitol; Flavin Mononucleotide; Homocysteine; Kinetics; Magnesium; Methionine; Methyltransferases; Oxidation-Reduction; Rhizobium; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Vitamin B 12 | 1974 |
The in vivo formation and turnover of S-adenosylmethionine from methionine in the liver of normal rats, of animals fed dimethylnitrosamine, and of partially hepatectomised animals.
Topics: Animals; Carbon Radioisotopes; Cell Division; Chromatography, Paper; Dimethylamines; Female; Hepatectomy; Liver; Liver Regeneration; Methionine; Nitrosamines; Rats; S-Adenosylmethionine; Time Factors | 1974 |
Incorporation of (14-C) ethanolamine and (3-H) methionine into phospholipids of rat brain and liver in vivo and in vitro.
Topics: Animals; Brain; Carbon Radioisotopes; Choline; Ethanolamines; In Vitro Techniques; Inositol; Liver; Male; Methionine; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Rats; S-Adenosylmethionine; Sphingomyelins; Synaptosomes; Tritium | 1974 |
Ethanol-induced changes in methionine metabolism in rat liver.
Topics: Animals; Cystathionine; Dietary Proteins; Ethanol; Homocysteine; Liver; Male; Methionine; Methyltransferases; Rats; S-Adenosylmethionine | 1974 |
[Significance of transmethylation and S-adenosylmethionine (SAM) in the management of Parkinson's disease with L-dopa].
Topics: Adenosine; Aged; Brain; Digestive System; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; Gastrointestinal Diseases; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney; Male; Methionine; Methylation; Nausea; Parkinson Disease; S-Adenosylmethionine; Vomiting | 1972 |
Carotenoid biosynthesis in Rhodopseudomonas spheroides. S-adenosylmethionine as the methylating agent in the biosynthesis of spheroidene and spheroidenone.
Topics: Carbon Radioisotopes; Carotenoids; Chromatography, Thin Layer; Methionine; Muramidase; Rhodobacter sphaeroides; S-Adenosylmethionine | 1973 |
The influence of methionine deprivation on restriction properties of Haemophilus influenzae Rd and Ra strains.
Topics: Bacteriophages; Endonucleases; Ethionine; Haemophilus influenzae; Methionine; Mutation; S-Adenosylmethionine | 1974 |
Studies on the regulation of one-carbon metabolism. II. Repression-derepression of serine hydroxymethyltransferase by methionine in Escherichia coli 113-3.
Topics: Ammonium Sulfate; Chemical Precipitation; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Repression; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Methionine; Methyltransferases; Molecular Weight; Oxidoreductases; S-Adenosylmethionine; Serine; Tetrahydrofolate Dehydrogenase; Thymine Nucleotides; Transferases; Uracil Nucleotides; Vitamin B 12 | 1972 |
Transmethylation of sterols in aerobically adapting Saccharomyces cerevisiae.
Topics: Adaptation, Physiological; Aerobiosis; Anaerobiosis; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Galactose; Glucose; Methionine; Methylation; Oxygen; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Sterols; Vitamin D | 1972 |
Regulation of the methionine feedback-sensitive enzyme in mutants of Salmonella typhimurium.
Topics: Acyltransferases; Cell-Free System; Culture Media; Drug Synergism; Enzyme Repression; Ethionine; Feedback; Genetics, Microbial; Homoserine; Leucine; Methionine; Mutation; S-Adenosylmethionine; Salmonella typhimurium; Stereoisomerism; Succinates | 1972 |
Transport of S-adenosylmethionine in Saccharomyces cerevisiae.
Topics: Adenosine; Azides; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Culture Media; Cyanides; Cycloheximide; Diploidy; Ethionine; Genes; Genetics, Microbial; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Methionine; Mutation; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Temperature | 1972 |
The mechanism of S-adenosyl-L-methionine synthesis by purified preparations of bakers' yeast.
Topics: Adenosine Triphosphate; Amino Acids; Ammonium Sulfate; Carbon Isotopes; Catalysis; Chemical Precipitation; Chromatography, Ion Exchange; Cyclopentanes; Enzyme Activation; Ethanol; Fluorine; Guanosine Triphosphate; Homocysteine; Kinetics; Methionine; Models, Chemical; Pentosyltransferases; Phosphoric Acids; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Sulfides | 1972 |
Regulation of the terminal reactions in methionine biosynthesis by vitamin B 12 and methionine.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Carbon Isotopes; Drug Antagonism; Enzyme Induction; Enzyme Repression; Escherichia coli; Genetics, Microbial; Kinetics; Methionine; Methyltransferases; Mutation; S-Adenosylmethionine; Salmonella typhimurium; Tetrahydrofolates; Transferases; Vitamin B 12 | 1972 |
Chemotaxis and methionine metabolism in Escherichia coli.
Topics: Bacteriological Techniques; Carbon Isotopes; Cell Fractionation; Cell Movement; Chemotaxis; Chromatography, Paper; Escherichia coli; Methionine; Micropore Filters; S-Adenosylmethionine; Spermidine; Sulfur Isotopes; Tritium | 1972 |
Methylation of purified transfer RNA preparations by extracts derived from rat kidney and kidney tumours.
Topics: Ammonium Sulfate; Animals; Carbon Isotopes; Chemical Precipitation; Enzyme Activation; Escherichia coli; Formates; Glutamates; Kidney; Kidney Neoplasms; Magnesium; Methionine; Methylation; Methyltransferases; Putrescine; Quaternary Ammonium Compounds; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spermidine | 1972 |
Deficiency of the DNA of Micrococcus radiodurans in methyladenine and methylcytosine.
Topics: Adenine Nucleotides; Carbon Isotopes; Cytosine Nucleotides; DNA, Bacterial; Escherichia coli; Methionine; Methylation; Methyltransferases; Micrococcus; RNA, Bacterial; S-Adenosylmethionine; Thymine Nucleotides; Tritium | 1972 |
Response of the intracellular adenosine triphosphate pool of Saccharomyces cerevisiae to growth inhibition induced by excess L-methionine.
Topics: Adenosine Triphosphate; Autoradiography; Chromatography, Thin Layer; Colorimetry; Culture Media; Methionine; Micropore Filters; Phosphates; Phosphorus Isotopes; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Stereoisomerism | 1972 |
Regulation of homocysteine biosynthesis in Salmonella typhimurium.
Topics: Acyltransferases; Bacteriological Techniques; Carbon Isotopes; Enzyme Repression; Feedback; Genetics, Microbial; Homocysteine; Homoserine; Hydro-Lyases; L-Serine Dehydratase; Lyases; Methionine; Molecular Biology; Mutation; S-Adenosylmethionine; Salmonella typhimurium; Spectrophotometry; Succinates; Tetrahydrofolates; Tritium; Vitamin B 12 | 1972 |
Specificities of tRNA methylases from mouse liver and plasmocytoma.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Escherichia coli; Hydrolysis; Liver; Methionine; Methyltransferases; Mice; Phenylalanine; Plasmacytoma; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Structure-Activity Relationship; Valine | 1972 |
Methionine adenosyltransferase and ethionine resistance in Saccharomyces cerevisiae.
Topics: Adenosine Triphosphate; Alleles; Culture Media; Diploidy; Ethionine; Haploidy; Methionine; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Transferases | 1972 |
A rapid assay procedure for ATP:L-methionine adenosyltransferase.
Topics: Adenosine Triphosphate; Carbon Isotopes; Cellulose; Chromatography, Ion Exchange; Evaluation Studies as Topic; Filtration; Ion Exchange; Ion Exchange Resins; Methionine; Methods; Paper; S-Adenosylmethionine; Saccharomyces cerevisiae; Time Factors; Transferases | 1972 |
An S-adenosylmethionine requirement for chemotaxis in Escherichia coli.
Topics: Chemotaxis; Chromatography, Paper; Drug Resistance, Microbial; Escherichia coli; Ethionine; Ligases; Methionine; Mutation; Nucleosides; S-Adenosylmethionine; Sulfates; Sulfur Isotopes; Transduction, Genetic | 1972 |
Polyamine metabolism in potassium-deficient bacteria.
Topics: Arginine; Bacterial Proteins; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Culture Media; Escherichia coli; Methionine; Mutation; Ornithine; Potassium; Putrescine; RNA, Bacterial; S-Adenosylmethionine; Sodium; Spermidine; Urea | 1972 |
In vivo synthesis of sulfur containing amino acids in Candida albicans.
Topics: Agar; Candida albicans; Cystathionine; Cysteine; Homocystine; Methionine; S-Adenosylmethionine; Sulfides; Zea mays | 1973 |
S-adenosyl methionine-mediated repression of methionine biosynthetic enzymes in Saccharomyces cerevisiae.
Topics: Adenosine; Adenosine Triphosphate; Culture Media; Enzyme Repression; Fungal Proteins; Methionine; Mutation; Oxidoreductases; Phosphotransferases; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfites; Transferases | 1973 |
Properties of metK mutants of Escherichia coli K-12.
Topics: Carbon Isotopes; Cell-Free System; Chromatography, Paper; Coliphages; Culture Media; Cystathionine; DNA, Bacterial; Escherichia coli; Fatty Acids; Genes; Hydro-Lyases; L-Serine Dehydratase; Leucine; Methionine; Methylation; Mutation; S-Adenosylmethionine; Sulfur Isotopes; Toluene; Transferases; Vibration | 1973 |
Methionine biosynthesis and S-adenosylmethionine degradation during an induced morphogenesis of Candida albicans.
Topics: Candida albicans; Carbon Isotopes; Cell-Free System; Culture Media; Glycine; Homocysteine; Methionine; Methyltransferases; Morphogenesis; S-Adenosylmethionine | 1973 |
Effects of regulatory mutations upon methionine biosynthesis in Saccharomyces cerevisiae: loci eth2-eth3-eth10.
Topics: Adenosine Triphosphate; Benzene; Cell-Free System; Enzyme Repression; Ethionine; Genes; Homocysteine; Methionine; Methyltransferases; Mutation; Nucleotidyltransferases; Oxidoreductases; S-Adenosylmethionine; Saccharomyces cerevisiae; Stereoisomerism; Sulfites; Transferases | 1973 |
Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12.
Topics: Adenosine Triphosphate; Culture Media; Cystathionine; Enzyme Repression; Escherichia coli; Folic Acid; Homocysteine; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Mutation; Oxidoreductases; S-Adenosylmethionine; Time Factors; Transferases; Vitamin B 12 | 1973 |
Methionine limitation in Escherichia coli K-12 by growth on the sulfoxides of D-methionine.
Topics: Adenosine Triphosphate; Carbon Radioisotopes; Cell-Free System; Cystathionine; Electrophoresis, Paper; Enzyme Repression; Escherichia coli; Hydro-Lyases; L-Serine Dehydratase; Ligases; Methionine; S-Adenosylmethionine; Stereoisomerism; Sulfoxides | 1973 |
Induction and repression in the S-adenosylmethionine and methionine biosynthetic systems of Saccharomyces cerevisiae.
Topics: Adenosine Triphosphate; Carbon Radioisotopes; Culture Media; Enzyme Induction; Enzyme Repression; Homocysteine; Methionine; Methyltransferases; Nucleotidyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Time Factors | 1973 |
Methylation of purified transfer RNAs by liver extracts from normal and mestranol-treated rats.
Topics: Ammonia; Animals; Base Sequence; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Paper; Escherichia coli; Female; Glutamates; Kinetics; Liver; Magnesium; Mestranol; Methionine; Putrescine; Rats; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Serine; Species Specificity; Spermidine; tRNA Methyltransferases | 1973 |
Biosynthesis of methionine and its control in wild type and regulatory mutants of Saccharomyces cerevisiae.
Topics: Autoradiography; Culture Media; Enzyme Repression; Genes, Regulator; Kinetics; Methionine; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae | 1973 |
Function of N2 methylguanine in phenylalanine transfer RNA.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Escherichia coli; Guanine; In Vitro Techniques; Isoleucine; Kinetics; Liver; Lysine; Methionine; Methylation; Nucleic Acid Conformation; Phenylalanine; Rabbits; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Triticum; tRNA Methyltransferases; Valine | 1973 |
Inhibition of ATP: L-methionine S-adenosyltransferase of bakers' yeast by structural analogues of ATP.
Topics: Adenosine; Adenosine Triphosphate; Binding Sites; Carbon Radioisotopes; Chromatography, Ion Exchange; Deoxyadenosines; Kinetics; Methionine; Organophosphonates; Phosphates; Protein Binding; S-Adenosylmethionine; Saccharomyces cerevisiae; Structure-Activity Relationship; Transferases | 1973 |
S-adenosylmethionine metabolism by members of the genus Candida.
Topics: Candida; Candida albicans; Carbon Radioisotopes; Cell-Free System; Chromatography; Culture Media; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet | 1973 |
Regulatory properties of adenosine triphosphate-L-methionine S-adenosyltransferase of rat liver.
Topics: Adenosine Triphosphate; Animals; Enzyme Activation; Escherichia coli; Kidney; Kinetics; Liver; Methionine; Neoplasms, Experimental; Rats; S-Adenosylmethionine; Saccharomyces cerevisiae; Spleen; Transferases | 1973 |
S-adenosylmethionine synthetase in methionine regulatory mutants of Salmonella typhimurium.
Topics: Adenosine Triphosphate; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Enzyme Repression; Genes, Regulator; Genetic Complementation Test; Kinetics; Methionine; Mutation; Phenotype; S-Adenosylmethionine; Salmonella typhimurium; Spermidine; Transferases; Ultrasonics | 1973 |
Deficiency in methionine adenosyltransferase resulting in limited repressibility of methionine biosynthetic enzymes in Aspergillus nidulans.
Topics: Aspergillus nidulans; Cysteine; Enzyme Repression; Escherichia coli; Membrane Transport Proteins; Methionine; Molecular Biology; Mutation; Oxidoreductases; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfates; Sulfites; Time Factors; Transferases | 1973 |
Regulation of one-carbon biosynthesis and utilization in Escherichia coli.
Topics: Adenine; Alcohol Oxidoreductases; Carbon Radioisotopes; Cell-Free System; Culture Media; Enzyme Repression; Escherichia coli; Formaldehyde; Glycine; Ligases; Methionine; Mutation; Nucleosides; Oxidoreductases; S-Adenosylmethionine; Serine; Spermidine; Tetrahydrofolates; Transferases | 1974 |
Escherichia coli formylmethionine tRNA: methylation of specific guanine and adenine residues catalyzed by HeLa cells tRNA methylases and the effect of these methylations on its biological properties.
Topics: Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Electrophoresis, Paper; Escherichia coli; HeLa Cells; Humans; Methionine; Methylation; Molecular Weight; Nucleic Acid Conformation; Oligonucleotides; Pancreas; Ribonucleases; Ribonucleotides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Tritium; tRNA Methyltransferases | 1974 |
Defective transport in S-adenosylmethionine synthetase mutants of Escherichia coli.
Topics: Adenosine Triphosphate; Amino Acids; Biological Transport; Carbon Radioisotopes; Cell Membrane; Chromatography, Gas; Escherichia coli; Fatty Acids; Glucose; Kinetics; Leucine; Lysine; Methionine; Methylglycosides; Mutation; Organoids; S-Adenosylmethionine; Species Specificity; Time Factors; Transferases; Tritium | 1974 |
Methionine biosynthesis in Saccharomyces cerevisiae: mutations at the regulatory locus ETH2. 3. Study of several homoallelic and heteroallelic diploids.
Topics: Alleles; Diploidy; Enzyme Repression; Ethionine; Genes, Recessive; Genes, Regulator; Methionine; Mutation; Phenotype; Polymers; S-Adenosylmethionine; Saccharomyces cerevisiae | 1974 |
Methionine biosynthesis in Saccharomyces cerevisiae: mutations at the regulatory locus ETH2. II. Physiological and biochemical data.
Topics: Alleles; Chromosome Mapping; Enzyme Repression; Ethionine; Genes, Regulator; Kinetics; Methionine; Mutation; Phenotype; S-Adenosylmethionine; Saccharomyces cerevisiae | 1974 |
Structural and conformational analogues of L-methionine as inhibitors of the enzymatic synthesis of S-adenosyl-l-methionine. I. Saturated and unsaturated aliphatic amino acids.
Topics: Adenosine; Alkylation; Amino Acids; Animals; Caproates; Carbon Radioisotopes; Chromatography, Ion Exchange; Depression, Chemical; Escherichia coli; Isomerism; Kinetics; Liver; Methionine; Molecular Conformation; Norleucine; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Transferases; Valerates; Valine; Yeasts | 1974 |
Structural and conformational analogues of L-methionine as inhibitors of the enzymatic synthesis of S-adenosyl-L-methionine. II. Aromatic amino acids.
Topics: Adenosine; Amino Acids; Animals; Electron Transport; Escherichia coli; Homocysteine; Homoserine; Hydrolysis; Liver; Malonates; Methionine; Molecular Conformation; Nitro Compounds; Phenylalanine; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Transferases; Tyrosine; Valerates; Yeasts | 1974 |
Acceptor activity of hypermethylated E. coli tRNAf-Met.
Topics: Amino Acyl-tRNA Synthetases; Base Sequence; Carbon Radioisotopes; Chromatography, Thin Layer; Escherichia coli; Formates; Isotope Labeling; Methionine; Methylation; Nucleic Acid Conformation; Oligonucleotides; Ribonucleotides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
The regulation of methionine and s-adenosylmethionine biosynthesis and utilization in mutants of Salmonella typhimurium with defects in s-adenosylmethionine synthetase.
Topics: Adenosine Triphosphate; Bacteriological Techniques; Biological Assay; Carbon Radioisotopes; Enzyme Repression; Membrane Transport Proteins; Methionine; Mutation; S-Adenosylmethionine; Salmonella typhimurium; Spermidine; Transferases | 1974 |
Isolation and in vitro restriction of unmethylated DNA from Escherichia coli K.
Topics: Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Gel; DNA Replication; DNA, Bacterial; Endonucleases; Escherichia coli; Isotope Labeling; Mathematics; Methionine; Methylation; Methyltransferases; Molecular Weight; Mutation; Nitrogen Isotopes; S-Adenosylmethionine; Temperature; Thymine; Tritium | 1974 |
Studies of a methionine-activating enzyme.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Carbamates; Cats; Chromatography, Paper; Cyclopentanes; Dogs; Electrophoresis, Starch Gel; Erythrocytes; Ethionine; Female; Guinea Pigs; Haplorhini; Humans; Hydrogen-Ion Concentration; Male; Methionine; Methods; Mice; Organ Specificity; Rabbits; Rats; S-Adenosylmethionine; Transferases; Tritium | 1972 |
Sai-1 mutation: saccharomyces cerevisiae: characteristics of inhibition by S-adenosylmethonine and S-adenosylhomocysteine and protection by methionine.
Topics: Adenine; Carbon Isotopes; Cell Fractionation; Enterococcus faecalis; Genetics, Microbial; Homocysteine; Methionine; Mutation; Protein Biosynthesis; RNA; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Uracil | 1972 |
[Role of sulfated amino acids in the growth of Corynebacterium sepedonicum (Spieck, et Kott) Skapt. et Burkh].
Topics: Amino Acids; Chromatography, Paper; Colorimetry; Corynebacterium; Culture Media; Cystathionine; Glutathione; Homocysteine; Homocystine; Methionine; S-Adenosylmethionine; Stereoisomerism; Sulfur | 1973 |
Differentiation of chick embryo cerebral hemispheres. 3. Incorporation of ( 3 H-methyl)methionine into 29 S, 18 S and 4 S RNAs.
Topics: Age Factors; Animals; Brain; Cell Differentiation; Chick Embryo; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Time Factors; Tritium; Uridine | 1973 |
The periodic synthesis of S-adenosylmethionine: protein methyltransferases during the HeLa S-3 cell cycle.
Topics: Amino Acids; Arginine; Carbon Isotopes; Cycloheximide; Cytarabine; Dactinomycin; DNA Replication; DNA, Neoplasm; HeLa Cells; Histones; Humans; Kinetics; Lysine; Methionine; Methylation; Methyltransferases; Mitosis; Neoplasm Proteins; S-Adenosylmethionine; Thymidine | 1973 |
Assay for S-adenosylmethionine: methionine methyltransferase.
Topics: Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Methionine; Methods; Methyltransferases; S-Adenosylmethionine | 1973 |
Effect of inhibitors of adenosine triphosphate: L-methionine S-adenosyltransferase on levels of S-adenosyl-L-methionine and L-methionine in normal and malignant mammalian tissues.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Caproates; Carbon Isotopes; Carcinoma 256, Walker; Female; Leucine; Leukemia L1210; Lung Neoplasms; Male; Melanoma; Methionine; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Rats; S-Adenosylmethionine; Time Factors; Transferases; Tritium | 1973 |
Studies on acute methionine toxicity. II. Inhibition of ribonucleic acid synthesis in guinea pig liver by methionine and ethionine.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Body Weight; DNA-Directed RNA Polymerases; Ethionine; Female; Guinea Pigs; Liver; Methionine; Orotic Acid; RNA; S-Adenosylmethionine; Templates, Genetic; Time Factors; Tritium; Uracil Nucleotides | 1973 |
The activity of dopamine-beta-hydroxylase and methionine-activating enzyme in blood of schizophrenic patients.
Topics: Adenosine Triphosphate; Catecholamines; Chronic Disease; Dopamine beta-Hydroxylase; Erythrocytes; Humans; Hydroxylation; Incubators; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia; Transferases; Tritium | 1973 |
Protein methylases during the development of rat brain.
Topics: Aging; Animals; Body Weight; Brain; Carbon Radioisotopes; Cell Nucleus; Cerebellum; Cytosol; Liver; Lysine; Medulla Oblongata; Mesencephalon; Methionine; Methyltransferases; Mice; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; S-Adenosylmethionine; Subcellular Fractions; Tritium | 1973 |
The synthesis of taurine from sulfate. V. Regulatory modifiers of the chick liver enzyme system.
Topics: Adenosine Monophosphate; Alanine; Allosteric Regulation; Animals; Chickens; Cysteine; Ethionine; Homocysteine; Liver; Methionine; Organophosphorus Compounds; S-Adenosylmethionine; Serine; Sulfinic Acids; Sulfonic Acids; Sulfur Radioisotopes; Sulfuric Acids; Sulfurtransferases; Taurine | 1973 |
Inhibition of a transmethylation reaction in the central nervous system-an experimental model for subacute combined degeneration of the cord.
Topics: Amino Acids; Animals; Cyclopentanes; Methionine; Mice; Nerve Fibers, Myelinated; S-Adenosylmethionine; Spinal Cord; Spinal Cord Diseases; Transferases | 1973 |
Methylation of exogenous 3,4-dihydroxyphenylalanine (,dopa)--effects on methyl group metabolism.
Topics: Animals; Brain; Carbon Radioisotopes; Dihydroxyphenylalanine; In Vitro Techniques; Kidney; Liver; Male; Methionine; Methylation; Muscles; Rats; RNA, Transfer; S-Adenosylmethionine; Time Factors; Yeasts | 1973 |
Enzymatic studies on the metabolism of the tetrahydrofurfuryl mercaptan moiety of thiamine tetrahydrofurfuryl disulfide. I. Microsomal S-transmethylase.
Topics: Animals; Ascorbic Acid; Benzenesulfonates; Carbon Radioisotopes; Chlorides; Chloromercuribenzoates; Chromatography; Cysteine; Disulfides; Furans; Glutathione; Intestine, Small; Kidney; Liver; Male; Mercury; Methionine; Methylation; Methyltransferases; Microsomes; Organometallic Compounds; Rats; S-Adenosylmethionine; Spectrophotometry, Infrared; Sulfhydryl Compounds; Thiamine; Tritium | 1973 |
Enzymes catalyzing the de novo synthesis of methyl groups in the brain and other tissues of the rat.
Topics: Aerobiosis; Alcohol Oxidoreductases; Animals; Brain; Carbon Radioisotopes; Dihydroxyphenylalanine; Female; Kidney; Liver; Male; Mercaptoethanol; Methionine; Methyltransferases; Rats; S-Adenosylmethionine; Serine; Sex Factors; Tetrahydrofolates; Transferases; Vitamin B 12; Vitamin K | 1973 |
Methionine metabolism in mammals: synthesis of S-adenosylhomocysteine in rat tissues.
Topics: Adenosine; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Dithiothreitol; Glucagon; Glutathione; Growth Hormone; Homocysteine; Hydrocortisone; Isotope Labeling; Liver; Male; Methionine; Organ Specificity; Rats; S-Adenosylmethionine; Thyroxine; Tritium | 1973 |
Stimulation of ornithine decarboxylase activity and inhibition of S-adenosyl-L-methionine decarboxylase activity in leukaemic mice by methylglyoxal bis(guanylhydrazone).
Topics: Adenosine; Amidines; Animals; Carboxy-Lyases; Depression, Chemical; Glyoxal; Hydrazones; Leukemia L1210; Male; Methionine; Mice; Ornithine; Polyamines; S-Adenosylmethionine; Spermidine; Stimulation, Chemical | 1973 |
5'-Methylthioadenosine and related compounds as precursors of S-adenosylmethionine in yeast.
Topics: Adenine; Adenosine; Aerobiosis; Candida; Carbon Radioisotopes; Deoxyadenosines; Methionine; Optical Rotation; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfides; Sulfur Radioisotopes; Thionucleosides; Time Factors | 1973 |
DNA methylation in isolated nuclei: old and new DNAs are methylated.
Topics: Aminopterin; Animals; Carbon Radioisotopes; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Paper; DNA; Fibroblasts; Kinetics; L Cells; Methionine; Methylation; Mice; S-Adenosylmethionine; Thymidine; Tritium | 1973 |
Relation between the hepatic action of drugs and the synthesis of subcellular structures.
Topics: Aminopyrine N-Demethylase; Analysis of Variance; Animals; Choline; Dactinomycin; Deficiency Diseases; Diet; Drug Interactions; In Vitro Techniques; Liver; Male; Methionine; Methylation; Methyltransferases; Microsomes, Liver; Phenobarbital; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Biosynthesis; Rats; S-Adenosylmethionine; Subcellular Fractions | 1974 |
Correlation between synthesis and methylation of DNA in HeLa cells.
Topics: Carbon Radioisotopes; Cell Division; Cell Nucleus; Chromatography, Paper; Cytosine; DNA, Neoplasm; HeLa Cells; Isotope Labeling; Methionine; Methylation; S-Adenosylmethionine; Thymidine; Time Factors; Tritium | 1974 |
Folic acid deficiency and methyl group metabolism in rat brain: effects of L-dopa.
Topics: Animals; Body Weight; Brain; Dihydroxyphenylalanine; Folic Acid; Folic Acid Deficiency; Kidney; Liver; Male; Methionine; Organ Size; Organ Specificity; Rats; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 1974 |
In vivo and in vitro utilization of labeled precursors for choline synthesis in mature Japanese quail as compared to rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Chickens; Choline; Coturnix; Ethanolamines; Female; In Vitro Techniques; Liver; Methionine; Methylamines; Methylation; Methyltransferases; Nutritional Requirements; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine; Serine; Species Specificity | 1974 |
Multiple regression analyses of the relationship structure and inhibitory effects of a series of substituted O-phenyl-DL-homoserines on adenosine triphosphate: L-methionine S-adenosyltransferase.
Topics: Adenosine Triphosphate; Homoserine; Isomerism; Methionine; Regression Analysis; S-Adenosylmethionine; Structure-Activity Relationship; Transferases | 1974 |
Physiological dependence of brain methionine and S-adenosylmethionine concentrations on serum amino acid pattern.
Topics: Adenosine; Animals; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Caseins; Circadian Rhythm; Dietary Carbohydrates; Dietary Proteins; Male; Methionine; Rats; S-Adenosylmethionine; Time Factors; Transferases; Tritium; Tyrosine | 1974 |
Structural and conformational analogues of L-methionine as inhibitors of the enzymatic synthesis of S-adenosyl-l-methionine. 3. Carbocyclic and heterocyclic amino acids.
Topics: Adenosine Triphosphate; Amantadine; Amino Acids; Animals; Bridged-Ring Compounds; Camphanes; Carboxylic Acids; Crystallography; Cyclopentanes; Heterocyclic Compounds; Hydrolysis; Indenes; Isomerism; Methionine; Molecular Conformation; Nitro Compounds; Pyrrolidines; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Sulfhydryl Compounds; Transferases; X-Ray Diffraction | 1974 |
The effects of diamines and polyamines on enzymic methylation of nucleic acid.
Topics: Acridines; Adenine; Amines; Animals; Biphenyl Compounds; Carbon Isotopes; Chromatography, Paper; Cytosine; Depression, Chemical; Dialysis; Escherichia coli; Guanine; Kidney; Liver; Magnesium; Male; Metabolism; Methionine; Methyltransferases; Osmolar Concentration; Phenanthridines; Polyamines; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spermine; Spleen; Stimulation, Chemical; Streptomycin; Thymine; Transferases | 1971 |
Methylation of DNA in ultraviolet-irradiated bacteria.
Topics: Adenine; Carbon Isotopes; Chromatography, Paper; Cytosine; Deoxyribonucleases; DNA; DNA, Bacterial; Escherichia coli; Methionine; Methylation; Methyltransferases; Nucleic Acid Denaturation; Pancreas; Radiation Effects; Ribonucleases; S-Adenosylmethionine; Time Factors; Tritium; Ultraviolet Rays; Uracil | 1971 |
Fragmented E. coli methionine tRNA f as methyl acceptor for rat liver tRNA methylase: alteration of the site of methylation by the conformational change of tRNA structure resulting from fragmentation.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis; Escherichia coli; Formates; Guanine; Liver; Methionine; Methylation; Methyltransferases; Nucleosides; Nucleotidyltransferases; Pancreas; Paper; Polynucleotides; Rats; Ribonucleases; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Transferases | 1971 |
The coding nature of valyl-transfer RNA binding to ribosomes during methionine starvation in E. coli 113-3.
Topics: Carbon Isotopes; Depression, Chemical; Escherichia coli; Genetic Code; Guanine Nucleotides; Liver; Methionine; Methylation; Methyltransferases; Mutation; Polynucleotides; Protein Binding; Ribosomes; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine; Stimulation, Chemical; Time Factors; Uracil Nucleotides; Valine | 1971 |
Aminoacylation and polypeptide synthesis with tRNA lacking ribothymidine.
Topics: Acylation; Amino Acids; Ammonium Chloride; Arginine; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Escherichia coli; Genetics, Microbial; Hydrogen-Ion Concentration; Kinetics; Ligases; Magnesium; Methionine; Methyltransferases; Mutation; Peptide Biosynthesis; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; S-Adenosylmethionine; Streptomycin; Thymidine; Uracil Nucleotides | 1971 |
An enzymatic derivative double isotope assay for L -methionine.
Topics: Adenosine Triphosphate; Adrenal Glands; Animals; Brain Chemistry; Carbon Isotopes; Chromatography, Ion Exchange; Escherichia coli; Kidney; Liver; Lung; Male; Mathematics; Methionine; Methods; Microchemistry; Rats; S-Adenosylmethionine; Spleen; Transferases; Tritium | 1971 |
S-adenosylmethionine in human blood.
Topics: Adenosine; Adult; Child; Child, Preschool; Humans; Leukemia; Methionine; Methyltransferases; Neoplasms; Neuroblastoma; Radioisotope Dilution Technique; S-Adenosylmethionine | 1971 |
Polyamine metabolism in mouse liver after partial hepatectomy.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Carboxy-Lyases; Electrophoresis; Escherichia coli; Half-Life; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Methionine; Mice; Ornithine; Polyamines; RNA; S-Adenosylmethionine; Spermidine; Spermine; Time; Transferases | 1971 |
Biosynthesis of 7,8-diaminopelargonic acid, a biotin intermediate, from 7-keto-8-aminopelargonic acid and S-adenosyl-L-methionine.
Topics: Adenosine; Adenosine Triphosphate; Amines; Amino Acids; Biotin; Cell-Free System; Chromatography, Paper; Culture Media; Electron Transport; Electrophoresis, Paper; Escherichia coli; Fatty Acids; Glucose; Keto Acids; Ketones; Magnesium; Methionine; S-Adenosylmethionine; Transaminases | 1971 |
The enzymic formation of O-acetylhomoserine in Bacillus subtilis and its regulation by methionine and S-adenosylmethionine.
Topics: Acetates; Acylation; Adenosine; Amino Acids; Bacillus subtilis; Carbon Isotopes; Cell-Free System; Cells, Cultured; Coenzyme A; Depression, Chemical; Escherichia coli; Feedback; Homoserine; Hydroxybutyrates; Lysine; Methionine; S-Adenosylmethionine; Succinates | 1971 |
S-adenosylmethionine and catechol-O-methyl-transferase in schizophrenia.
Topics: Adenosine; Adult; Aged; Catechol O-Methyltransferase; Female; Humans; Male; Methionine; Methyltransferases; Middle Aged; S-Adenosylmethionine; Schizophrenia | 1972 |
Purification and properties of an o-dihydricphenol meta-O-methyltransferase from cell suspension cultures of parsley and its relation to flavonoid biosynthesis.
Topics: Adenosine Triphosphate; Ammonium Sulfate; Carbon Isotopes; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Disc; Flavonoids; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Light; Magnesium; Methionine; Methyltransferases; Phenols; Plants; Radiation Effects; S-Adenosylmethionine; Structure-Activity Relationship; Transferases | 1972 |
Studies on the activation of lysine-2,3-aminomutase by (-)-S-adenosyl-L-methionine.
Topics: Adenosine; Butyrates; Carbon Isotopes; Chromatography, Thin Layer; Clostridium; Dialysis; Electrophoresis, Paper; Enzyme Activation; Isomerases; Kinetics; Lysine; Methionine; Propylamines; Protein Binding; S-Adenosylmethionine; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship; Trichloroacetic Acid; Ultraviolet Rays | 1972 |
[Various effects of SAM dependent transmethylations in hepatology].
Topics: Adenosine; Biopsy; Chronic Disease; Fatty Liver; Hepatitis; Humans; Injections, Intraperitoneal; Lipid Metabolism; Liver Cirrhosis; Liver Diseases; Liver Glycogen; Methionine; Methylation; S-Adenosylmethionine | 1972 |
[Preliminary clinico-geriatric trials of S-adenosylmethionine (coenzyme of biologic transmethylation)].
Topics: Adenosine; Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Female; Humans; Injections, Intramuscular; Liver Diseases; Male; Mental Disorders; Methionine; S-Adenosylmethionine | 1972 |
[Relationship between S-adenosylmethionine and lipid metabolism].
Topics: Adult; Cell Membrane Permeability; Cholesterol; Diabetes Mellitus; Female; Heart Diseases; Humans; Immunoelectrophoresis; Lipid Metabolism; Lipoproteins; Lung Diseases; Male; Methionine; Middle Aged; Platelet Adhesiveness; S-Adenosylmethionine | 1972 |
Pancreas acinar cell differentiation. V. Significance of methyl groups in morphologic and enzymatic development.
Topics: Amylases; Animals; Choline; Chymotrypsin; Culture Media; Cysteine; Cystine; Lipase; Methionine; Methylation; Microscopy, Electron; Organ Culture Techniques; Pancreas; Rats; RNA, Transfer; S-Adenosylmethionine | 1972 |
Biosynthesis of Se-methylselenocysteine and S-methylcysteine in Astragalus bisculcatus. Origin of the selenomethyl and the thiomethyl groups.
Topics: Carbon Isotopes; Chromatography, Paper; Cystathionine; Cysteine; Methionine; Methylation; Plants; Radioisotopes; S-Adenosylmethionine; Selenium | 1972 |
RNA metabolism in HeLa cells at reduced temperature. II. Steps in the processing of transfer RNA.
Topics: Cell Fractionation; Cell Nucleus; Cell-Free System; Cytoplasm; Electrophoresis, Disc; HeLa Cells; Methionine; Methylation; Phosphorus Isotopes; RNA, Transfer; S-Adenosylmethionine; Temperature; Tritium; Uridine | 1972 |
The enzymatic formation of methanol from S-adenosylmethionine by various tissues of the rat.
Topics: Adenosine; Adrenal Glands; Animals; Benzoates; Brain; Carbon Isotopes; Chromatography, Paper; In Vitro Techniques; Kidney; Liver; Lung; Methanol; Methionine; Methyltransferases; Myocardium; Pancreas; Rats; S-Adenosylmethionine; Spleen; Sulfur Isotopes; Tritium | 1972 |
[Changes induced by S-adenosylmethionine (SAM) in the cholesterol and triglyceride plasma levels and in the beta-alpha lipoprotein ratio in cases of hyperlipemia. (Preliminary note)].
Topics: Adenosine; Aged; Cholesterol; Female; Humans; Hyperlipidemias; Lipid Mobilization; Lipoproteins; Male; Methionine; Middle Aged; S-Adenosylmethionine; Triglycerides | 1972 |
Protein methylation during the development of rat brain.
Topics: Animals; Animals, Newborn; Arginine; Brain; Carbon Isotopes; Carboxylic Acids; Cytoplasm; Ethanol; Fetus; Histones; Lysine; Methionine; Methylation; Methyltransferases; Nerve Tissue Proteins; Proteins; Rats; S-Adenosylmethionine; Solubility; Sulfuric Acids; Transferases; Tritium | 1972 |
An assay for N 5 -methyltetrahydrofolate-homocysteine transmethylase activity using instant thin-layer chromatography.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Folic Acid; Formaldehyde; Homocysteine; Kidney; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine | 1972 |
Modification of pigmentation and cell-wall structure of Rhodotorula aurantiaca by culture in the presence of sulfur amino acids.
Topics: Acetone; Carbohydrates; Carotenoids; Cell Aggregation; Cell Fractionation; Cell Wall; Culture Media; Glycoside Hydrolases; Homocysteine; Lipids; Methionine; Mitosporic Fungi; Phosphorus; Pigmentation; Polysaccharides; Proteins; S-Adenosylmethionine; Snails; Solvents; Spectrum Analysis; Spheroplasts | 1972 |
Methionine adenosyltransferase. A double-isotope derivative, enzymatic assay.
Topics: Adenosine Triphosphate; Animals; Brain; Carbon Isotopes; Chromatography, Ion Exchange; Liver; Male; Melatonin; Methionine; Methods; Methyltransferases; Pineal Gland; Rats; S-Adenosylmethionine; Transferases; Tritium | 1972 |
Mechanism of mammalian cobalamin-dependent methionine biosynthesis.
Topics: Alkylation; Animals; Carbon Isotopes; Darkness; Dithiothreitol; Electrophoresis, Disc; Enzyme Activation; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxocobalamin; Iodides; Kidney; Kinetics; Light; Mathematics; Mercaptoethanol; Methionine; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Oxidation-Reduction; Radiation Effects; S-Adenosylmethionine; Swine; Tritium | 1971 |
L-dopa and S-adenosylmethionine.
Topics: Adenosine; Carbon Isotopes; Dihydroxyphenylalanine; Humans; Methionine; Parkinson Disease; S-Adenosylmethionine; Time Factors; Tritium | 1971 |
Methylation of nuclear proteins by dimethylnitrosamine and by methionine in the rat in vivo.
Topics: Alkylation; Amino Acids; Animals; Carbon Isotopes; Carcinogens; Chromatography, Ion Exchange; Chromatography, Paper; Female; Formaldehyde; Histones; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Methionine; Methylation; Necrosis; Nitrosamines; Rats; S-Adenosylmethionine; Sulfonic Acids; Tritium | 1971 |
Enzymatic methylation of skeletal muscle contractile proteins.
Topics: Actins; Actomyosin; Animals; Animals, Newborn; Carbon Isotopes; Chick Embryo; Chickens; Chromatography, Gel; Chromatography, Ion Exchange; Histidine; Kinetics; Lysine; Methionine; Methylation; Muscle Proteins; Muscles; Myofibrils; Myosins; S-Adenosylmethionine; Sarcoplasmic Reticulum; Ultracentrifugation | 1971 |
S-adenosylmethionine in a neuroblastoma.
Topics: Abdominal Neoplasms; Adenosine; Catechol O-Methyltransferase; Catecholamines; Chromatography; Cystathionine; Humans; Indicators and Reagents; Male; Methionine; Methods; Neoplasm Metastasis; Neuroblastoma; Norepinephrine; Orbital Neoplasms; S-Adenosylmethionine; Time Factors; Tritium; Vanilmandelic Acid | 1971 |
[Transmethylation processes in senile involution: a working hypothesis].
Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; RNA; S-Adenosylmethionine; Vitamin B 12 | 1971 |
Transfer RNA methylases during sea urchin embryogenesis.
Topics: Acetates; Animals; Carbon Isotopes; Chemical Precipitation; Cytosine Nucleotides; Deoxyribonucleases; Ethanol; Female; Guanine; Hydrolysis; Methionine; Methylation; Methyltransferases; Ovum; Phenols; Potassium; Pronase; RNA, Transfer; S-Adenosylmethionine; Sea Urchins; Time Factors; Tritium; Uracil Nucleotides | 1971 |
Stimulation by estrogens of ornithine and S-adenosylmethionine decarboxylases in the immature rat uterus.
Topics: Animals; Benzopyrans; Carbon Isotopes; Carboxy-Lyases; Cycloheximide; Diethylstilbestrol; Enzyme Activation; Estradiol; Estrogens; Estrus; Female; Flavonoids; Kinetics; Liver; Methionine; Organ Specificity; Ornithine; Pregnancy; Puromycin; Putrescine; Rats; S-Adenosylmethionine; Testosterone; Tritium; Uridine; Uterus | 1971 |
Studies on acute methionine toxicity. I. Nucleolar disaggregation in guinea pig hepatic cells with methionine or ethionine and its reversal with adenine.
Topics: Adenine; Adenosine Triphosphate; Animals; Cell Nucleolus; Chromatin; Ethionine; Female; Guinea Pigs; Humans; Liver; Male; Methionine; Microscopy, Electron; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Time Factors | 1971 |
Oxidative deamination of sulfur amino acids by bacterial and snake venom L-amino acid oxidase.
Topics: Adenosine; Alanine; Amino Acid Oxidoreductases; Animals; Catalase; Cattle; Chromatography, Thin Layer; Cysteine; Cystine; Homocysteine; Homocystine; Hydrogen-Ion Concentration; Kinetics; Liver; Methionine; Models, Biological; Models, Structural; Oxygen Consumption; Proteus; S-Adenosylmethionine; Snakes; Species Specificity; Sulfides; Sulfur; Venoms | 1971 |
Polyamines. (1) Enhanced s-adenosyl-L-methionine decarboxylase in rapid growth systems, and (2) the relationships between polyamine concentration and RNA accumulation.
Topics: Aging; Amines; Animals; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chick Embryo; Enzyme Induction; Growth Hormone; Hepatectomy; Liver; Liver Regeneration; Male; Methionine; Ornithine; Polyamines; Rats; RNA; S-Adenosylmethionine; Spermine; Time Factors; Tritium; Uridine | 1971 |
Mutation of Saccharomyces cerevisiae preventing uptake of S-adenosylmethionine.
Topics: Adenine; Carbon Isotopes; Colorimetry; Crosses, Genetic; Culture Media; Cysteine; Genetics, Microbial; Homocysteine; Methionine; Mutation; Nucleosides; S-Adenosylmethionine; Saccharomyces; Serine; Threonine | 1971 |
Effect of serum on the synthesis of RNA and of DNA in the cultured lens epithelium of the chick embryo: initiation of lens fiber formation in vitro.
Topics: Adenosine Triphosphate; Animals; Blood; Cattle; Centrifugation, Density Gradient; Cesium; Chick Embryo; Chlorides; Culture Techniques; Dactinomycin; DNA; Electrophoresis; Epithelium; Female; Fetus; Lens, Crystalline; Methionine; Methylation; Nucleosides; RNA; RNA, Ribosomal; S-Adenosylmethionine; Stimulation, Chemical; Sucrose; Tritium | 1971 |
Catabolism of betaine and its relationship to cobalamin overproduction.
Topics: Betaine; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Choline; Coenzyme A; Glycine; Homocysteine; Methionine; Methylation; Nucleosides; Porphyrins; Pseudomonas; S-Adenosylmethionine; Succinates; Sucrose; Vitamin B 12 | 1971 |
The methyl-folate trap and the supply of S-adenosylomethionine.
Topics: Brain; Brain Diseases; Folic Acid; Methionine; Methylation; S-Adenosylmethionine; Vitamin B 12 Deficiency | 1981 |
A sensitive assay method for the measurement of S-adenosylmethionine in tissue.
Topics: Acid Anhydride Hydrolases; Animals; Diet; Kinetics; Liver; Methionine; Methionine Adenosyltransferase; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1984 |
The methylation in vitro of myelin basic protein by arginine methylase from mouse spinal cord.
Topics: Animals; Methionine; Methylation; Mice; Myelin Basic Protein; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine; Spinal Cord | 1980 |
Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine.
Topics: Azacitidine; Cell Line; Culture Media; DNA; Dose-Response Relationship, Drug; Floxuridine; Fragile X Syndrome; Homocysteine; Humans; Karyotyping; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Chromosome Aberrations | 1983 |
Inhibitors of cyclic nucleotide phosphodiesterases inhibit protein carboxyl methylation in intact blood platelets.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Blood Platelets; Dipyridamole; Humans; Hydrogen-Ion Concentration; Hydrolysis; Methionine; Mopidamol; Papaverine; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine | 1984 |
Effects of a methyl-deficient diet on rat liver phosphatidylcholine biosynthesis.
Topics: Animals; Choline Deficiency; Diacylglycerol Cholinephosphotransferase; Diet; Female; Liver; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Novel sensory adaptation mechanism in bacterial chemotaxis to oxygen and phosphotransferase substrates.
Topics: Acclimatization; Aerobiosis; Chemotaxis; Escherichia coli; Kinetics; Methionine; Methyltransferases; Mutation; Oxygen Consumption; Phosphotransferases; S-Adenosylmethionine; Salmonella typhimurium; Transduction, Genetic | 1982 |
Reduced availability of endogenously synthesized methionine for S-adenosylmethionine formation in methionine-dependent cancer cells.
Topics: Cell Division; Cell Line; Cell Transformation, Viral; Homocysteine; Humans; Methionine; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1982 |
Reduced free-methionine in methionine-dependent SV40-transformed human fibroblasts synthesizing apparently normal amounts of methionine.
Topics: Cell Line; Cell Transformation, Viral; Cells, Cultured; Humans; Methionine; Protein Biosynthesis; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1983 |
The role of the one-carbon cycle in neuropsychiatric disease.
Topics: Bipolar Disorder; Depressive Disorder; Glycine Hydroxymethyltransferase; Humans; Kinetics; Methionine; Methionine Adenosyltransferase; Neurocognitive Disorders; Parkinson Disease; S-Adenosylmethionine; Schizophrenia; Synaptic Transmission; Transferases | 1984 |
Depression of adenosylmethionine content of Escherichia coli by thioglycerol.
Topics: Amino Acids; Autoradiography; Escherichia coli; Glycerol; Methionine; S-Adenosylmethionine | 1983 |
Initiation of meiosis and sporulation of Saccharomyces cerevisiae by sulfur or guanine deprivation.
Topics: Culture Media; Guanine; Meiosis; Methionine; Mutation; Nucleotides; Purines; Pyrimidines; S-Adenosylmethionine; Saccharomyces cerevisiae; Spores, Fungal; Sulfur; Uracil | 1984 |
Isolation of D-aspartic acid beta-methyl ester from erythrocyte carboxyl methylated proteins.
Topics: Aspartic Acid; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Endopeptidases; Erythrocyte Membrane; Humans; Hydrogen-Ion Concentration; Hydrolysis; Membrane Proteins; Methionine; Radioisotope Dilution Technique; S-Adenosylmethionine; Tritium | 1984 |
Protein and lipid methylation by methionine and S-adenosylmethionine in Myxococcus xanthus.
Topics: Bacterial Proteins; Biological Transport; Chloramphenicol; Kinetics; Lipid Metabolism; Methionine; Methylation; Molecular Weight; Myxococcales; S-Adenosylmethionine | 1983 |
Carboxyl methylation of cytosolic proteins in intact human erythrocytes. Identification of numerous methyl-accepting proteins including hemoglobin and carbonic anhydrase.
Topics: Blood Proteins; Carbonic Anhydrases; Cytosol; Erythrocytes; Hemoglobins; Humans; Kinetics; Methionine; Methylation; Molecular Weight; S-Adenosylmethionine; Tritium | 1984 |
A rapid high-performance liquid chromatographic procedure for the simultaneous determination of methionine, ethionine, S-adenosylmethionine, S-adenosylethionine, and the natural polyamines in rat tissues.
Topics: Adenosine; Amino Acids, Sulfur; Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Ethionine; Liver; Male; Methionine; Pancreas; Polyamines; Prostate; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1984 |
Elevated overall rates of transmethylation in cell lines from diverse human tumors.
Topics: Adenosylhomocysteinase; Cell Line; Homocysteine; Humans; Hydrolases; Methionine; Methylation; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1984 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Effect of L-dihydroxyphenylalanine (L-dopa) and methionine on tissue S-adenosylmethionine concentrations in cobalamin-inactivated fruit bats.
Topics: Animals; Brain; Chiroptera; Levodopa; Liver; Methionine; Nervous System; Nitrous Oxide; S-Adenosylmethionine; Vitamin B 12 Deficiency | 1984 |
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.
Topics: Adenosine; Aspartic Acid; Erythrocyte Membrane; Erythrocytes; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Tissue S-adenosylmethionine levels in fruit bats (Rousettus aegyptiacus) with nitrous oxide-induced neuropathy.
Topics: Animals; Brain; Cerebellar Ataxia; Chiroptera; Diet; Folic Acid; Liver; Methionine; Nitrous Oxide; Paralysis; S-Adenosylmethionine; Vitamin B 12 | 1983 |
In vitro methylation of histones in sea urchin nuclei during early embryogenesis.
Topics: Animals; Cell Nucleus; Embryo, Nonmammalian; Female; Histones; Kinetics; Methionine; Methylation; Protein Methyltransferases; S-Adenosylmethionine; Sea Urchins; Tritium | 1983 |
Methionine can open the methyl folate trap.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Methionine; Nitrous Oxide; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1983 |
Regulation of cobalamin and folate metabolism by methionine in human bone marrow cultures.
Topics: Bone Marrow Cells; Cells, Cultured; Deoxyuridine; Folic Acid Deficiency; Glutathione; Humans; Methionine; S-Adenosylmethionine; Vitamin B 12 Deficiency | 1983 |
The transmethylation and one-carbon cycle hypotheses of schizophrenia.
Topics: Brain; Catecholamines; Folic Acid; Humans; Kinetics; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia | 1983 |
Enzymatic synthesis of S-adenosyl-L-methionine from L-methionine and ATP.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Methionine; Methionine Adenosyltransferase; Rabbits; S-Adenosylmethionine; Stereoisomerism; Swine | 1983 |
Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines.
Topics: Cell Line; Homocysteine; Humans; Methionine; Models, Biological; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Metabolic conversion of neplanocin A to S-neplanocylmethionine by mouse L 929 cells.
Topics: Adenosine; Animals; Biotransformation; L Cells; Methionine; Methyltransferases; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity | 1984 |
Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet.
Topics: Animals; Cell Nucleus; Choline Deficiency; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Differential membrane protein carboxyl-methylation of intact human erythrocytes by exogenous methyl donors.
Topics: Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Humans; Hydrolysis; Membrane Proteins; Methionine; Methylation; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Growth inhibition by methionine analog inhibitors of S-adenosylmethionine biosynthesis in the absence of polyamine depletion.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cell Line; Leucine; Leukemia L1210; Methionine; Methionine Adenosyltransferase; Mice; Neoplasm Proteins; Polyamines; S-Adenosylmethionine; Structure-Activity Relationship | 1984 |
Methionine metabolism in mammals. Distribution of homocysteine between competing pathways.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Male; Methionine; Methyltransferases; Models, Biological; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
5-Methylcytosine formation in wheat embryo DNA.
Topics: 5-Methylcytosine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Kinetics; Methionine; Methyltransferases; Plants; S-Adenosylmethionine; Serine; Triticum | 1980 |
A decrease in S-adenosylmethionine synthetase activity increases the probability of spontaneous sporulation.
Topics: Adenosine; Bacillus subtilis; Ethionine; Guanosine Triphosphate; Methionine; Methionine Adenosyltransferase; Mutation; S-Adenosylmethionine; Selenomethionine; Spores, Bacterial; Transferases | 1982 |
Intermittent hypermethioninaemia associated with normal hepatic methionine adenosyltransferase activity: report of a case.
Topics: Female; Humans; Infant; Liver; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine; Transferases | 1982 |
Protein carboxyl methylation increases in parallel with differentiation of neuroblastoma cells.
Topics: Animals; Cell Differentiation; Cell Line; Clone Cells; Kinetics; Methionine; Methylation; Mice; Neoplasm Proteins; Neuroblastoma; S-Adenosylmethionine | 1983 |
A simple radioactivity assay for measurement of methionine adenosyltransferase activity by aqueous chromatography.
Topics: Animals; Buffers; Carbon Radioisotopes; Chromatography, Ion Exchange; Humans; Hydrogen-Ion Concentration; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Transferases | 1983 |
Effects of nitrous oxide-induced inactivation of cobalamin on methionine and S-adenosylmethionine metabolism in the rat.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Brain; Liver; Male; Methionine; Methyltransferases; Nitrous Oxide; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Vitamin B 12 | 1983 |
Chronic cobalamin inactivation impairs folate polyglutamate synthesis in the rat.
Topics: Adenosine; Animals; Deoxyadenosines; Folic Acid; Formyltetrahydrofolates; Liver; Male; Methionine; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tetrahydrofolates; Thionucleosides; Vitamin B 12; Vitamin B 12 Deficiency | 1983 |
Intestinal absorption of S-adenosyl-L-methionine in humans.
Topics: Female; Humans; Intestinal Absorption; Male; Methionine; S-Adenosylmethionine | 1983 |
Effect of nitrous oxide and methionine treatments on hepatic S-adenosylmethionine and methylation reactions in the rat.
Topics: Animals; Formates; Liver; Male; Methionine; Methylation; Nitrous Oxide; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tetrahydrofolates | 1983 |
S-adenosyl-L-methionine synthetase from human erythrocytes: role in the regulation of cellular S-adenosylmethionine levels.
Topics: Cytosol; Erythrocytes; Humans; Kinetics; Methionine; Methionine Adenosyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Transferases | 1983 |
Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Lung; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Testis; Tissue Distribution; Vitamin B 12 Deficiency | 1983 |
Measurements of S-adenosylmethionine and L-homocysteine metabolism in cultured human lymphoid cells.
Topics: Cells, Cultured; Homocysteine; Humans; Lymphocytes; Mathematics; Methionine; S-Adenosylmethionine; Time Factors | 1983 |
Formation of ethylene from methionine. Reactivity of radiolytically produced oxygen radicals and effect of substrate activation.
Topics: Chromatography, Gas; Dose-Response Relationship, Radiation; Ethylenes; Free Radicals; Methionine; Oxygen; Pulse Radiolysis; Pyridoxal Phosphate; S-Adenosylmethionine; Superoxide Dismutase; X-Rays | 1980 |
Changing reactivity of receptor carboxyl groups during bacterial sensing.
Topics: Chemotactic Factors; Chemotaxis; Escherichia coli; Kinetics; Methionine; Molecular Weight; Radioisotope Dilution Technique; S-Adenosylmethionine; Salmonella typhimurium; Tritium | 1981 |
Multiple sites of methylation in the methyl accepting chemotaxis proteins of Escherichia coli.
Topics: Bacterial Proteins; Chemotactic Factors; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Membrane Proteins; Methionine; Methyl-Accepting Chemotaxis Proteins; Methylation; Peptide Fragments; S-Adenosylmethionine; Tritium | 1981 |
[3H-Methyl]-methionine as possible methyl donor for formation of 5'-terminus of in vitro synthesized mRNA of cytoplasmic polyhedrosis virus of silkworm Bombyx mori.
Topics: Animals; Bombyx; DNA-Directed RNA Polymerases; Electrophoresis, Paper; Insect Viruses; Methionine; RNA, Messenger; S-Adenosylmethionine; Virion | 1981 |
Characteristics of protein carboxyl methylation in the rat hypothalamus.
Topics: Animals; Hypothalamus; Kinetics; Male; Methionine; Methylation; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Synaptosomes; Tritium | 1982 |
Methionine metabolism in mammals: concentration of metabolites in rat tissues.
Topics: Amino Acids, Sulfur; Animals; Cysteine; Cystine; Dietary Proteins; Homeostasis; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfhydryl Compounds; Tissue Distribution | 1982 |
Decreased levels of S-adenosylmethionine in the livers of rats fed phenobarbital and DDT.
Topics: Animals; Body Weight; Choline; DDT; Diet; Eating; Liver; Male; Methionine; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1982 |
Stimulation of fatty acid methylation in human red cell membranes by phospholipase A2 activation.
Topics: Dose-Response Relationship, Drug; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Fatty Acids; Humans; Lung; Melitten; Methionine; Methylation; Oleic Acid; Oleic Acids; Phospholipases; Phospholipases A; Phospholipases A2; S-Adenosylmethionine; Substrate Specificity | 1982 |
Use of S-adenosylmethionine as an index of methionine recycling in rat liver slices.
Topics: Animals; In Vitro Techniques; Liver; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1982 |
Changes in tRNA methyltransferase activity and cellular S-adenosylmethionine content following methionine deprivation.
Topics: Animals; Carcinoma 256, Walker; Cell Division; Fibroblasts; Humans; In Vitro Techniques; Lymphoma; Methionine; Neoplasms, Experimental; S-Adenosylmethionine; tRNA Methyltransferases | 1980 |
Regulatory properties of O-acetyl-L-serine sulfhydrylase of Cephalosporium acremonium: evidence of an isoenzyme and its importance in cephalosporin C biosynthesis.
Topics: Acremonium; Cephalosporins; Chromatography, Gel; Cysteine; Cysteine Synthase; Isoenzymes; Lyases; Methionine; Mutation; S-Adenosylmethionine; Time Factors | 1980 |
Mitochondrial alterations induced by selenium in guinea pig myocardium.
Topics: Animals; Guinea Pigs; Male; Methionine; Microscopy, Electron; Mitochondria, Heart; Pyruvates; S-Adenosylmethionine; Selenium | 1981 |
How vitamin B12 acts.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Animals; Folic Acid; Humans; Methionine; Pteroylpolyglutamic Acids; S-Adenosylmethionine; Thymidine; Vitamin B 12 Deficiency | 1981 |
Methionine utilization in long-term human lymphoid cell lines.
Topics: Blood Proteins; Cell Count; Cell Line; Cell Survival; Humans; Kinetics; Lymphocytes; Methionine; S-Adenosylmethionine; Spermidine; Spermine | 1981 |
Cerebral enzymatic activities during chronic hyperammonemia and treatment with S-adenosyl-L-methionine, adenosine and methionine in the rat.
Topics: Adenosine; Ammonia; Animals; Brain; Female; Methionine; Mitochondria; Rats; S-Adenosylmethionine | 1981 |
Feedback inhibition by methionine and S-adenosylmethionine, and desensitization of homoserine O-acetyltransferase in Brevibacterium flavum.
Topics: Acetyltransferases; Brevibacterium; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Feedback; Homoserine; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Methionine; S-Adenosylmethionine | 1981 |
The biosynthesis of polyamines in the brain of audiogenic seizure-susceptible and -resistant deermice.
Topics: Acoustic Stimulation; Animals; Brain; Chromatography, High Pressure Liquid; Methionine; Peromyscus; Polyamines; Putrescine; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures; Spermidine; Spermine | 1981 |
Carboxymethylation of membrane proteins of irreversibly sickled erythrocytes.
Topics: Anemia, Sickle Cell; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Methionine; Methylation; Reference Values; S-Adenosylmethionine; Tritium | 1981 |
Reduced erythrocyte membrane protein methylation in sickle cell anemia.
Topics: Anemia, Sickle Cell; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Lipids; Membrane Proteins; Methionine; Methylation; Phospholipids; Reference Values; S-Adenosylmethionine; Tritium | 1981 |
An inverse correlation between hepatic ornithine decarboxylase and S-adenosylmethionine in rats.
Topics: Animals; Carboxy-Lyases; Cell Division; Choline Deficiency; Diet; Liver; Male; Methionine; Ornithine Decarboxylase; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1981 |
Polyamine biosynthesis and metabolism in normal and virus-infected plant protoplasts.
Topics: Chloroplasts; Light; Methionine; Mosaic Viruses; Plant Viruses; Plants; Polyamines; Protoplasts; S-Adenosylmethionine; Spermidine Synthase; Spermine Synthase | 1981 |
In vivo carboxyl methylation of human eruthrocyte membrane proteins.
Topics: Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Methionine; Methylation; Puromycin; S-Adenosylmethionine | 1980 |
The effect of the methionine antagonist L-2-amino-4-methoxy-trans-3-butenoic acid on the growth and metabolism of Walker carcinosarcoma in vitro.
Topics: Aminobutyrates; Animals; Carcinoma 256, Walker; Cells, Cultured; DNA, Neoplasm; Methionine; Methylation; Neoplasm Proteins; RNA, Neoplasm; RNA, Transfer; S-Adenosylmethionine | 1980 |
Influence of exogenous L-3,4,-dihydroxyphenylalanine (L-dopa) on the methionine and s-adenosylmethionine concentrations in the brain and other tissues [proceedings].
Topics: Aging; Animals; Brain; Iproniazid; Kidney; Levodopa; Liver; Methionine; Organ Specificity; Rats; S-Adenosylmethionine | 1980 |
S-Adenosylmethionine and S-adenosylhomocystein metabolism in isolated rat liver. Effects of L-methionine, L-homocystein, and adenosine.
Topics: Adenosine; Animals; DNA; Female; Histones; Homocysteine; Kinetics; Liver; Methionine; Perfusion; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.
Topics: 5-Methylcytosine; Aneuploidy; Azacitidine; Blotting, Southern; Chromosomes, Fungal; Crosses, Genetic; Cytosine; DNA, Fungal; Genes, Fungal; Genetic Complementation Test; Methionine; Methylation; Mutation; Neurospora crassa; Phenotype; S-Adenosylmethionine | 1993 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
A model for DNA binding and enzyme action derived from crystallographic studies of the TaqI N6-adenine-methyltransferase.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; DNA; DNA-Binding Proteins; Glycine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific) | 1995 |
Investigation of monovalent cation activation of S-adenosylmethionine synthetase using mutagenesis and uranyl inhibition.
Topics: Adenosine Triphosphate; Cations, Monovalent; Enzyme Activation; Escherichia coli; Glutamic Acid; Methionine; Methionine Adenosyltransferase; Mutagenesis, Site-Directed; Polyphosphates; Potassium Chloride; S-Adenosylmethionine; Uranium Compounds | 1995 |
Fate of soluble methionine in African trypanosomes: effects of metabolic inhibitors.
Topics: Adenosine; Animals; Half-Life; Methionine; S-Adenosylmethionine; Trypanocidal Agents; Trypanosoma brucei brucei | 1995 |
Methionine inhibits developmental aggregation of Myxococcus xanthus by blocking the biosynthesis of S-adenosyl methionine.
Topics: Amino Acids; Bacterial Adhesion; Chemotaxis; Ethionine; Gene Expression Regulation, Bacterial; Methionine; Myxococcus xanthus; S-Adenosylmethionine; Selenomethionine; Spores, Bacterial | 1995 |
Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos.
Topics: Adenosylhomocysteinase; Animals; Catalase; Copper; Copper Sulfate; Culture Techniques; Drug Interactions; Embryonic and Fetal Development; Embryonic Development; Female; Homocysteine; Homocystine; Hydrolases; Methionine; Neural Tube Defects; Oxidation-Reduction; Pregnancy; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism; Teratogens; Vitamin B 12 | 1994 |
Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats.
Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Genes, myc; Liver; Male; Methionine; Methylation; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1995 |
Methylation in fertilised and parthenogenetic preimplantation mouse embryos.
Topics: Animals; DNA Modification Methylases; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Genomic Imprinting; Homocysteine; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Parthenogenesis; Pregnancy; S-Adenosylmethionine | 1994 |
Involvement of folic acid and methionine in the synthesis of certain membrane-associated nucleotide sugars by Enterococcus hirae.
Topics: Cell Fractionation; Cell Membrane; Cell-Free System; Enterococcus; Folic Acid; Methionine; Monosaccharides; S-Adenosylmethionine; Serine; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars | 1994 |
In vitro and in vivo 13C and 31P NMR analyses of phosphocholine metabolism in rat glioma cells.
Topics: Animals; Carbon Isotopes; Cell Division; Choline; Ethanolamines; Glioma; Magnetic Resonance Spectroscopy; Methionine; Organophosphorus Compounds; Phosphatidylcholines; Phosphatidylserines; Phosphorus Isotopes; Phosphorylcholine; Rats; Rats, Inbred F344; S-Adenosylmethionine; Tumor Cells, Cultured | 1994 |
The vacuolar compartment is required for sulfur amino acid homeostasis in Saccharomyces cerevisiae.
Topics: Amino Acids, Sulfur; Cloning, Molecular; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Homeostasis; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfur; Trans-Activators; Transcription, Genetic; Vacuoles | 1994 |
Electrostatic activation of Escherichia coli methionine repressor.
Topics: Apoproteins; Bacterial Proteins; Base Sequence; Chemical Phenomena; Chemistry, Physical; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydrogen Bonding; Methionine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Operator Regions, Genetic; Protein Binding; Protein Conformation; Repressor Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes.
Topics: Adenosine Triphosphate; Amino Acids, Sulfur; Animals; Cell Count; Cysteine; Cystine; Glutathione; Hepatoblastoma; Humans; Liver; Liver Neoplasms; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tumor Cells, Cultured | 1994 |
Nitrous oxide inactivation of cobalamin-dependent methionine synthase from Escherichia coli: characterization of the damage to the enzyme and prosthetic group.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Electrochemistry; Escherichia coli; Homocysteine; Methionine; Molecular Sequence Data; Nitrous Oxide; Oxidation-Reduction; Peptide Fragments; Peptide Mapping; S-Adenosylmethionine; Tetrahydrofolates; Trypsin; Vitamin B 12 | 1994 |
Vitamin B-6 deficiency vs folate deficiency: comparison of responses to methionine loading in rats.
Topics: Animals; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Vitamin B 6 Deficiency | 1994 |
Methionine synthase inactivation by nitrous oxide during methionine loading of normal human fibroblasts. Homocysteine remethylation as determinant of enzyme inactivation and homocysteine export.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Enzyme Activation; Extracellular Space; Fetus; Fibroblasts; Folic Acid; Homocysteine; Humans; Infant; Lung; Male; Methionine; Methylation; Nitrous Oxide; S-Adenosylmethionine | 1993 |
Dietary betaine promotes generation of hepatic S-adenosylmethionine and protects the liver from ethanol-induced fatty infiltration.
Topics: Animals; Betaine; Fatty Liver, Alcoholic; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Triglycerides | 1993 |
S-adenosylmethionine metabolism in herpes simplex virus type 2-infected cells.
Topics: Animals; Biotransformation; Cell Line, Transformed; Cells, Cultured; Embryo, Mammalian; Kinetics; Methionine; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Simplexvirus; Sulfur Radioisotopes; Tritium | 1993 |
Methionine toxicity in the rat in relation to hepatic accumulation of S-adenosylmethionine: prevention by dietary stimulation of the hepatic transsulfuration pathway.
Topics: Amino Acids; Animals; Body Weight; Diet; Feeding Behavior; Glycine; Kidney; Liver; Male; Methionine; Muscles; Rats; Rats, Wistar; S-Adenosylmethionine; Serine | 1993 |
Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils.
Topics: Cell Membrane; Cytosol; GTP-Binding Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Methionine; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Methyltransferases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); rap GTP-Binding Proteins; rho-Specific Guanine Nucleotide Dissociation Inhibitors; S-Adenosylmethionine; Signal Transduction; Tritium | 1993 |
At least four regulatory genes control sulphur metabolite repression in Aspergillus nidulans.
Topics: Arylsulfatases; Aspergillus nidulans; Carbon-Oxygen Lyases; Chromosome Mapping; Chromosomes, Fungal; Crosses, Genetic; Cysteine Synthase; Genes, Fungal; Genes, Regulator; Genes, Suppressor; Genetic Linkage; Homocysteine; Lyases; Methionine; Multienzyme Complexes; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; Sulfate Adenylyltransferase; Sulfur | 1993 |
The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance.
Topics: Adenosine Triphosphate; Animals; Brain; Chromatography, High Pressure Liquid; Drug Interactions; Levodopa; Male; Methionine; Methionine Adenosyltransferase; Mice; Parkinson Disease; S-Adenosylmethionine | 1993 |
Effect of nitrous oxide exposure on maternal and embryonic S-adenosylmethionine levels and ornithine decarboxylase activity.
Topics: Animals; Embryo, Mammalian; Female; Liver; Methionine; Nitrous Oxide; Ornithine Decarboxylase; Pregnancy; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1993 |
S-adenosyl-L-methionine and the liver.
Topics: Animals; Glutathione; Humans; Liver; Liver Cirrhosis; Methionine; Methionine Adenosyltransferase; Rats; S-Adenosylmethionine | 1993 |
Ethynylestradiol protection against methyl insufficiency in castrated male Wistar/Furth rats fed a methionine-choline-deficient diet.
Topics: Animals; Body Weight; Castration; Choline Deficiency; Ethinyl Estradiol; Liver; Lung; Male; Methionine; Organ Size; Pancreas; Rats; Rats, Inbred WF; S-Adenosylhomocysteine; S-Adenosylmethionine | 1993 |
Mutations affecting the biosynthesis of S-adenosylmethionine cause reduction of DNA methylation in Neurospora crassa.
Topics: Amino Acids; Culture Media; DNA, Fungal; Genotype; Methionine; Methylation; Mutation; Neurospora crassa; S-Adenosylmethionine; Temperature | 1995 |
Crithidia luciliae: effect of purine starvation on S-adenosyl-L-methionine uptake and protein methylation.
Topics: Adenosine; Animals; Crithidia; Cycloheximide; Decarboxylation; Methionine; Methylation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Purines; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1995 |
Carbon flow through the hepatic folate-dependent one-carbon pool is not altered in vitamin A-deficient rats.
Topics: Animals; Carbon; Carbon Radioisotopes; Diterpenes; Folic Acid; Liver; Male; Methionine; Random Allocation; Rats; Rats, Sprague-Dawley; Retinyl Esters; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tritium; Vitamin A; Vitamin A Deficiency | 1996 |
Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Apoptosis; Cell Division; Deoxyuracil Nucleotides; Ethanol; Folic Acid; Homocysteine; Liver; Male; Methionine; Proliferating Cell Nuclear Antigen; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Thymine Nucleotides | 1996 |
Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Erythrocytes; Homocysteine; Humans; Mercaptopurine; Methionine; Methotrexate; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1996 |
A methyl-accepting protein involved in multiple-sugar chemotaxis by Cellulomonas gelida.
Topics: Bacterial Proteins; Carbohydrate Metabolism; Cell Fractionation; Cell Membrane; Cellobiose; Chemotaxis; Culture Media; Gram-Positive Asporogenous Rods; Membrane Proteins; Methanol; Methionine; Methyl-Accepting Chemotaxis Proteins; Methylation; Mutation; S-Adenosylmethionine | 1996 |
Improved electro-transformation of highly DNA-restrictive corynebacteria with DNA extracted from starved Escherichia coli.
Topics: Corynebacterium; Culture Media; DNA, Bacterial; Electroporation; Escherichia coli; Methionine; Plasmids; S-Adenosylmethionine; Transformation, Genetic | 1996 |
Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Kinetics; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1996 |
Methionine derivatives diminish sulphide damage to colonocytes--implications for ulcerative colitis.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Colitis, Ulcerative; Colon; Humans; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Scintillation Counting; Sulfides; Vitamin U | 1996 |
Valproate-induced developmental modifications maybe partially prevented by coadministration of folinic acid and S-adenosylmethionine.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Female; Fetus; Leucovorin; Liver; Methionine; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; S-Adenosylmethionine; Valproic Acid | 1996 |
Influence of osmotic stress on protein methylation in resealed erythrocytes.
Topics: Binding Sites; Biological Transport, Active; Erythrocytes; Humans; In Vitro Techniques; Membrane Proteins; Methionine; Methionine Adenosyltransferase; Methylation; Osmotic Pressure; Ovalbumin; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Proteins; S-Adenosylmethionine | 1997 |
Met31p and Met32p, two related zinc finger proteins, are involved in transcriptional regulation of yeast sulfur amino acid metabolism.
Topics: Amino Acid Sequence; Chromosome Mapping; Cloning, Molecular; Consensus Sequence; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Methionine; Molecular Sequence Data; Mutagenesis, Insertional; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Transcription, Genetic; Zinc Fingers | 1997 |
Transport of S-adenosylmethionine in isolated rat liver mitochondria.
Topics: Animals; Biological Transport; Carrier Proteins; Kinetics; Methionine; Mitochondria, Liver; Phospholipids; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 1997 |
Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Administration, Oral; Adult; Female; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1997 |
Nerve growth factor-specific regulation of protein methylation during neuronal differentiation of PC12 cells.
Topics: Adenosine; Animals; Cell Differentiation; Cell-Free System; DNA Methylation; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Homocysteine; Kinetics; Methionine; Methylation; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Protein Processing, Post-Translational; Rats; S-Adenosylmethionine; Signal Transduction; Tritium | 1997 |
Augmentation of mitochondrial reduced glutathione by S-adenosyl-L-methionine administration in ischemia-reperfusion injury of the rat steatotic liver induced by choline-methionine-deficient diet.
Topics: Animals; Choline Deficiency; Glutathione; Glutathione Disulfide; Ischemia; Liver; Male; Methionine; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury; S-Adenosylmethionine | 1998 |
Dietary methionine level affects linoleic acid metabolism through phosphatidylethanolamine N-methylation in rats.
Topics: Adenine; Animals; Body Weight; Cholesterol; Dietary Proteins; Fatty Acids; Linoleic Acid; Lipids; Liver; Male; Methionine; Methylation; Organ Size; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Wistar; S-Adenosylmethionine | 1998 |
Exogenous S-adenosyl-methionine methylates phospholipids located on the outer cell surface of isolated rat hepatocytes.
Topics: Adenosylhomocysteinase; Animals; Cell Membrane; Cells, Cultured; Enzyme Inhibitors; Hydrolases; Kinetics; Liver; Membrane Lipids; Methionine; Methylation; Phospholipids; Rats; S-Adenosylmethionine | 1998 |
S-adenosylmethionine deficiency and TNF-alpha in lipopolysaccharide-induced hepatic injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Choline Deficiency; Glutathione; Lipopolysaccharides; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tumor Necrosis Factor-alpha | 1998 |
Effects of intermediates of methionine metabolism and nucleoside analogs on S-adenosylmethionine transport by Trypanosoma brucei brucei and a drug-resistant Trypanosoma brucei rhodesiense.
Topics: Adenosine; Animals; Arsenicals; Drug Resistance; Methionine; Polyamines; Purine Nucleosides; S-Adenosylmethionine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 1998 |
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc | 1998 |
S-adenosyl-L-methionine attenuates ischemia-reperfusion injury of steatotic livers.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Choline Deficiency; Fatty Liver; Glutathione; Glutathione Disulfide; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Methionine; Mitochondria, Liver; Rats; Rats, Wistar; Reperfusion Injury; S-Adenosylmethionine | 1998 |
Measurement of plasma S-adenosylmethionine and S-adenosylhomocysteine as their fluorescent isoindoles.
Topics: Administration, Oral; Chromatography, High Pressure Liquid; Cyanides; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Indoles; Methionine; Naphthalenes; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine; Temperature | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
Metabolic effects of a methylthioadenosine phosphorylase substrate analog on African trypanosomes.
Topics: Adenosine; Animals; Biological Transport; Deoxyadenosines; Methionine; Models, Chemical; Molecular Structure; Polyamines; Purine-Nucleoside Phosphorylase; Putrescine; S-Adenosylmethionine; Spermidine; Structure-Activity Relationship; Substrate Specificity; Thionucleosides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 1999 |
Methionine adenosyltransferase S-nitrosylation is regulated by the basic and acidic amino acids surrounding the target thiol.
Topics: Amino Acids; Animals; Catalytic Domain; Gene Expression Regulation, Enzymologic; Glutathione; Liver; Methionine; Methionine Adenosyltransferase; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Nitric Oxide; Nitroso Compounds; Rats; Rats, Wistar; S-Adenosylmethionine; S-Nitrosoglutathione; Sulfhydryl Compounds | 1999 |
D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia.
Topics: Amino Acid Sequence; Aminopyridines; Animals; Benzazepines; Binding Sites; Carbon Radioisotopes; CHO Cells; Clozapine; Cricetinae; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Formates; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Methionine; Mutagenesis, Site-Directed; Neuroblastoma; Phospholipids; Phosphorylation; Piperidines; Psychotic Disorders; Pyridines; Pyrroles; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; S-Adenosylmethionine; Salicylamides; Schizophrenia; Transfection; Tumor Cells, Cultured | 1999 |
Role of S-adenosyl-L-methionine in the treatment of liver diseases.
Topics: Animals; Humans; Liver Cirrhosis, Alcoholic; Liver Diseases; Methionine; Middle Aged; Rats; S-Adenosylmethionine | 1999 |
Methyl donor for 1-methyladenine biosynthesis in starfish ovarian follicle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cyclic AMP; Gonads; Kinetics; Methionine; Phosphodiesterase Inhibitors; S-Adenosylmethionine; Second Messenger Systems; Starfish | 1999 |
Methionine reduces spontaneous and alkylation-induced mutagenesis in Saccharomyces cerevisiae cells deficient in O6-methylguanine-DNA methyltransferase.
Topics: Alkylation; DNA Damage; DNA Repair; DNA, Fungal; Dose-Response Relationship, Drug; Intracellular Fluid; Methionine; Methylnitronitrosoguanidine; Mutagenesis; O(6)-Methylguanine-DNA Methyltransferase; Oxidation-Reduction; S-Adenosylmethionine; Saccharomyces cerevisiae | 1999 |
Gene sam1 encoding adenosylmethionine synthetase: effects of its expression in the fission yeast Schizosaccharomyces pombe.
Topics: Amino Acid Sequence; Genes, Fungal; Methionine; Methionine Adenosyltransferase; Molecular Sequence Data; S-Adenosylmethionine; Schizosaccharomyces | 2000 |
The biosynthesis of methylated amino acids in the active site region of methyl-coenzyme M reductase.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Chromatography, High Pressure Liquid; Chymotrypsin; Glutamine; Mass Spectrometry; Metalloporphyrins; Methane; Methanobacterium; Methionine; Methylation; Molecular Sequence Data; Molecular Structure; Oxidoreductases; Peptide Fragments; Protein Processing, Post-Translational; S-Adenosylmethionine; Sequence Analysis | 2000 |
High-dose folic acid supplementation in rats: effects on gestation and the methionine cycle.
Topics: Animals; Dietary Supplements; Female; Fetal Weight; Folic Acid; Methionine; Methylation; Nutritional Status; Pregnancy; Pregnancy Outcome; Rats; Rats, Wistar; S-Adenosylmethionine | 2000 |
Energetics of S-adenosylmethionine synthetase catalysis.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Catalysis; Computer Simulation; Diphosphates; Escherichia coli; Fluorescence; Hydrolysis; Isomerism; Kinetics; Ligands; Methionine; Methionine Adenosyltransferase; Oxygen; Oxygen Isotopes; Phosphates; Polyphosphates; S-Adenosylmethionine; Solvents; Thermodynamics; Titrimetry; Water | 2000 |
Kinetics of methionine transport and metabolism by Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.
Topics: Allosteric Regulation; Animals; Biological Transport; Cytosol; Humans; Kinetics; Methionine; Methylation; Protein Biosynthesis; Proteins; S-Adenosylmethionine; Sulfur; Thermodynamics; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 2000 |
Hysteretic behavior of methionine adenosyltransferase III. Methionine switches between two conformations of the enzyme with different specific activity.
Topics: Acid Anhydride Hydrolases; Adenosine Triphosphate; Animals; Gene Expression Regulation, Enzymologic; Isoenzymes; Kinetics; Liver; Male; Methionine; Methionine Adenosyltransferase; Models, Chemical; Nitric Oxide; Rats; S-Adenosylmethionine | 2000 |
A substrate switch: a new mode of regulation in the methionine metabolic pathway.
Topics: Animals; Cysteine; Glycine N-Methyltransferase; Isoenzymes; Liver; Methionine; Methionine Adenosyltransferase; Methyltransferases; Models, Biological; S-Adenosylmethionine | 2000 |
LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases.
Topics: Arginine; Cell Line; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Humans; Kinetics; Lipoproteins, LDL; Methionine; Nitric Oxide Synthase; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2000 |
DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats.
Topics: Animals; Choline Deficiency; Colon; Colonic Neoplasms; Comet Assay; DNA; DNA Damage; DNA Methylation; Folic Acid; Folic Acid Deficiency; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Polyamines and thiols in the cytoprotective effect of L-cysteine and L-methionine on carbon tetrachloride-induced hepatotoxicity.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Cysteine; Cytoprotection; Dose-Response Relationship, Drug; Glutathione; Glutathione Transferase; Hepatocytes; L-Lactate Dehydrogenase; Male; Maleates; Methionine; Mitoguazone; Polyamines; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Sulfhydryl Compounds | 2000 |
Reverse methionine biosynthesis from S-adenosylmethionine in eukaryotic cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Deoxyadenosines; Fungal Proteins; Gene Expression Regulation; Homocysteine S-Methyltransferase; Membrane Proteins; Methionine; Molecular Sequence Data; S-Adenosylmethionine; Saccharomyces cerevisiae Proteins; Thionucleosides; Vitamin B 12; Vitamin U; Yeasts | 2000 |
S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver.
Topics: Animals; Cell Differentiation; Dose-Response Relationship, Drug; Ethionine; Gene Expression Regulation, Enzymologic; Isoenzymes; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; Rats, Wistar; S-Adenosylmethionine; Tubercidin | 2000 |
Isolated hypermethioninemia: measurements of S-adenosylmethionine and choline.
Topics: Choline; Humans; Isoenzymes; Methionine; Methionine Adenosyltransferase; Nervous System Diseases; S-Adenosylmethionine | 2000 |
Occurrence of transsulfuration in synthesis of L-homocysteine in an extremely thermophilic bacterium, Thermus thermophilus HB8.
Topics: Culture Media; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Gene Expression Regulation, Bacterial; Homocysteine; Lyases; Methionine; S-Adenosylmethionine; Sulfur; Temperature; Thermus thermophilus | 2001 |
COMT-dependent protection of dopaminergic neurons by methionine, dimethionine and S-adenosylmethionine (SAM) against L-dopa toxicity in vitro.
Topics: Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Survival; Cells, Cultured; Dopamine; Enzyme Inhibitors; Levodopa; Methionine; Neurons; Neuroprotective Agents; Rats; S-Adenosylmethionine | 2001 |
Novel methylated triterpenoids of the gammacerane series from the nitrogen-fixing bacterium Bradyrhizobium japonicum USDA 110.
Topics: Bradyrhizobium; Chromatography, Thin Layer; Cyclization; Deuterium; Gas Chromatography-Mass Spectrometry; Lyases; Magnetic Resonance Spectroscopy; Methionine; Methylation; Phylogeny; Polyisoprenyl Phosphates; Rhodopseudomonas; S-Adenosylmethionine; Symbiosis; Triterpenes | 2001 |
SAMe as it ever was?
Topics: AIDS Dementia Complex; Clinical Trials as Topic; Humans; Methionine; S-Adenosylmethionine | 1999 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Wy-14,643-induced hypomethylation of the c-myc gene in mouse liver.
Topics: Administration, Oral; Animals; Blotting, Southern; Cell Division; Cell Nucleus; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Genes, myc; Injections, Intraperitoneal; Liver; Methionine; Mice; Mice, Inbred Strains; Peroxisome Proliferators; Proliferating Cell Nuclear Antigen; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2001 |
Retinoid compounds activate and induce hepatic glycine N-methyltransferase in rats.
Topics: Animals; Enzyme Activation; Enzyme Induction; Glycine N-Methyltransferase; Liver; Male; Methionine; Methylation; Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tretinoin | 2001 |
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Cardiovascular Diseases; Dopa Decarboxylase; Down-Regulation; Drug Interactions; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Parkinson Disease; S-Adenosylmethionine; Up-Regulation | 2001 |
Methylation is involved in the Ustilago maydis mating response.
Topics: Cyclic AMP; Ethionine; Homocysteine; Methionine; Methylation; Methyltransferases; Mutation; Pheromones; Plants; Reproduction; S-Adenosylmethionine; Signal Transduction; Ustilago | 2001 |
Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in mouse liver and the effect of methionine on their concentrations.
Topics: Animals; Chromatography, High Pressure Liquid; Liver; Methionine; Mice; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet | 2001 |
Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Child; Child, Preschool; Diet; Female; Glycine N-Methyltransferase; Hepatomegaly; Humans; Liver; Methionine; Methyltransferases; S-Adenosylmethionine; Sarcosine | 2001 |
Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice.
Topics: Animals; Biomarkers; Choline Deficiency; Diet; DNA Methylation; Folic Acid Deficiency; Intestinal Neoplasms; Methionine; Mice; Neoplasms; Precancerous Conditions; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Constitutive overexpression of cystathionine gamma-synthase in Arabidopsis leads to accumulation of soluble methionine and S-methylmethionine.
Topics: Arabidopsis; Carbon-Oxygen Lyases; Ethionine; Fruit; Gene Expression Regulation; Gene Silencing; Immunoblotting; Methionine; Mutation; Plant Roots; Plant Shoots; Plant Structures; Plants, Genetically Modified; S-Adenosylmethionine; Threonine; Transcription, Genetic; Up-Regulation; Vitamin U | 2002 |
Reductive cleavage of S-adenosylmethionine by biotin synthase from Escherichia coli.
Topics: Biotin; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Kinetics; Methionine; Models, Chemical; Mutation; S-Adenosylmethionine; Spectroscopy, Mossbauer; Sulfurtransferases; Time Factors | 2002 |
The N-terminal region of Arabidopsis cystathionine gamma-synthase plays an important regulatory role in methionine metabolism.
Topics: Arabidopsis; Aspartic Acid; Carbon-Oxygen Lyases; Escherichia coli; Ethylenes; Gene Expression Regulation, Enzymologic; Genetic Complementation Test; Isoleucine; Lysine; Methionine; Mutation; Nicotiana; Phenotype; Plant Shoots; Plants, Genetically Modified; S-Adenosylmethionine; Threonine; Vitamin U | 2002 |
High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L-methionine synthetase 3 gene.
Topics: Arabidopsis; Chromosome Mapping; Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Complementation Test; Lignin; Methionine; Methionine Adenosyltransferase; Mutation; Phenotype; S-Adenosylmethionine; Sequence Homology, Amino Acid | 2002 |
Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy.
Topics: Adult; Female; Glutathione; HIV Infections; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; S-Adenosylmethionine; Spinal Cord Diseases; Vitamin B 12 | 2002 |
L-Homoserine: a novel excreted metabolic marker of hepatitis B abnormally produced in liver from methionine.
Topics: Alkyl and Aryl Transferases; Biomarkers; Hepatitis B; Homoserine; Humans; Hydrolases; Liver; Methionine; Models, Biological; S-Adenosylmethionine | 2002 |
S-adenosylmethionine is substrate for carrier mediated transport at the blood-brain barrier in vitro.
Topics: Adenosine; Amino Acid Transport System L; Animals; Binding, Competitive; Biological Transport, Active; Blood-Brain Barrier; Carrier Proteins; Cell Line, Transformed; Dose-Response Relationship, Drug; Endothelium, Vascular; Kinetics; Membrane Proteins; Methionine; Models, Biological; Nucleoside Transport Proteins; Rats; S-Adenosylmethionine; Symporters; Tritium | 2002 |
Global expression profile of Bacillus subtilis grown in the presence of sulfate or methionine.
Topics: Bacillus subtilis; Bacterial Proteins; Culture Media; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Methionine; Oligonucleotide Array Sequence Analysis; Repressor Proteins; S-Adenosylmethionine; Sulfates; Sulfur; Transcription, Genetic | 2002 |
S-adenosyl-methionine-induced apoptosis in PC12 cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Cell Differentiation; Culture Media, Conditioned; DNA Fragmentation; Intracellular Fluid; L-Lactate Dehydrogenase; Methionine; Neurons; Parkinsonian Disorders; PC12 Cells; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Hepatic glycine N-methyltransferase is up-regulated by excess dietary methionine in rats.
Topics: Animals; Dietary Proteins; Dose-Response Relationship, Drug; Glycine N-Methyltransferase; Kidney; Liver; Male; Methionine; Methyltransferases; Pancreas; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Up-Regulation; Weight Gain | 2002 |
Acute valproate administration impairs methionine metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Anticonvulsants; Betaine-Homocysteine S-Methyltransferase; Female; Folic Acid; Glutathione; Glutathione Disulfide; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methyltransferases; Models, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Teratogens; Valproic Acid; Vitamin B 6 | 2002 |
Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine.
Topics: Adult; Carbon Isotopes; Homocysteine; Humans; Kinetics; Liver Cirrhosis, Alcoholic; Male; Methionine; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tritium | 2002 |
Scavengers protection of cells against ALA-based photodynamic therapy-induced damage.
Topics: Aminolevulinic Acid; Animals; Antioxidants; Cell Line; Cell Survival; Free Radical Scavengers; Glutathione; Mammary Neoplasms, Experimental; Methionine; Mice; Photochemotherapy; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiation-Sensitizing Agents; S-Adenosylmethionine; Tryptophan | 2002 |
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
Topics: Anemia; Anemia, Pernicious; Cysteine; Dipeptides; Folic Acid; Glutathione; Homocysteine; Humans; Memory Disorders; Methionine; Movement Disorders; Nervous System Diseases; Retrospective Studies; S-Adenosylmethionine; Sensation Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
[Enhancement of the production of SAM by overexpression of SAM synthetase in Pichia pastoris].
Topics: Bleomycin; Cell Division; Drug Resistance; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Methionine; Methionine Adenosyltransferase; Pichia; Plasmids; Promoter Regions, Genetic; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Transformation, Genetic | 2003 |
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine.
Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; RNA, Messenger; S-Adenosylmethionine; Tumor Cells, Cultured | 2003 |
Methionine metabolism in liver diseases.
Topics: Humans; Hyperhomocysteinemia; Liver; Liver Diseases; Methionine; S-Adenosylmethionine | 2003 |
S-adenosylmethionine transport in Rickettsia prowazekii.
Topics: Adenosine; Anion Transport Proteins; Bacterial Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Escherichia coli; Ethionine; Ethylmaleimide; Methionine; Rickettsia prowazekii; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice.
Topics: Alkynes; Amino Acids; Animals; Betaine; Biological Transport; Cystathionine; Cystathionine gamma-Lyase; Cysteine Dioxygenase; Dioxygenases; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Glycine; Liver; Methionine; Mice; Mice, Inbred ICR; Oxygenases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine | 2003 |
Altered methionine metabolism in long living Ames dwarf mice.
Topics: Aging; Animals; Brain; Cystathionine beta-Synthase; DNA Methylation; Glycine N-Methyltransferase; Liver; Male; Methionine; Methionine Adenosyltransferase; Methyltransferases; Mice; Mice, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Increased response of liver microsomal delta 6-desaturase activity to dietary methionine in rats.
Topics: Animals; Arachidonic Acid; Caseins; Dietary Proteins; Dietary Supplements; Linoleic Acid; Methionine; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylmethionine; Stearoyl-CoA Desaturase | 2003 |
Structural studies of the interaction of S-adenosylmethionine with the [4Fe-4S] clusters in biotin synthase and pyruvate formate-lyase activating enzyme.
Topics: Acetyltransferases; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Coenzymes; Enzyme Activation; Enzymes; Escherichia coli Proteins; Iron; Iron-Sulfur Proteins; Lysine; Methionine; Multienzyme Complexes; S-Adenosylmethionine; Spectrometry, X-Ray Emission; Spectrum Analysis; Substrate Specificity; Sulfurtransferases | 2003 |
Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Catalysis; Escherichia coli; Escherichia coli Proteins; Homocysteine; Methionine; Methylation; Mutation, Missense; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Temperature; Tetrahydrofolates; Vitamin B 12 | 2003 |
Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Catalysis; Crystallography, X-Ray; Escherichia coli; Hydrolysis; Ligands; Liver; Methionine; Methionine Adenosyltransferase; Models, Chemical; Models, Molecular; Protein Binding; Protein Isoforms; Rats; Recombinant Proteins; S-Adenosylmethionine | 2003 |
Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats.
Topics: Administration, Oral; Animals; Betaine; Ethanol; Hepatocytes; Male; Methionine; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
S-Adenosylmethionine; a new intermediate formed enzymatically from L-methionine and adenosinetriphosphate.
Topics: Adenosine; Adenosine Triphosphate; Methionine; S-Adenosylmethionine | 1953 |
The formation of S-adenosylmethionine in yeast.
Topics: Adenosine; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae; Yeasts | 1957 |
The preparation of S-adenosylmethionine.
Topics: Adenosine; Methionine; S-Adenosylmethionine; Yeasts | 1957 |
The stability and hydrolysis of S-adenosylmethionine; isolation of S-ribosylmethionine.
Topics: Adenosine; Hydrolysis; Methionine; Ribose; S-Adenosylmethionine | 1958 |
Formation of alpha-amino-gamma-butyrolactone from S-adenosylmethionine.
Topics: 4-Butyrolactone; Adenosine; Butyrates; Lipid Metabolism; Methionine; S-Adenosylmethionine | 1958 |
Enzymatic cleavage of S-adenosylmethionine.
Topics: Adenosine; Biophysical Phenomena; Cytokinesis; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae | 1959 |
Metabolism of 2,6-diaminopurine: S-adenosylmethionine as methyl donor for 2-methylamino-6-aminopurine synthesis.
Topics: 2-Aminopurine; Adenine; Adenosine; Metabolic Networks and Pathways; Methionine; Purines; S-Adenosylmethionine | 1959 |
Improved procedure for the isolation of S-adenosylmethionine and S-adenosylethionine.
Topics: Adenosine; Ethionine; Methionine; S-Adenosylmethionine; Yeasts | 1959 |
The mechanism of the enzymatic cleavage of S-adenosylmethionine to alpha-amino-gamma-butyrolactone.
Topics: 4-Butyrolactone; Adenosine; Amino Acids; Cytokinesis; Methionine; S-Adenosylmethionine | 1959 |
Enzymatic O-methylation of N-acetylserotonin to melatonin.
Topics: Acetylserotonin O-Methyltransferase; Melatonin; Methionine; Methylation; Pineal Gland; S-Adenosylmethionine; Serotonin; Transferases | 1960 |
Localization of S-adenosylmethionine in Candida utilis by ultraviolet microscopy.
Topics: Candida; Methionine; Microscopy, Ultraviolet; S-Adenosylmethionine | 1959 |
S-adenosylmethionine in the vacuole of Candida utilis.
Topics: Candida; Methionine; S-Adenosylmethionine; Vacuoles | 1960 |
[Enzymatic methylation of 2-hydroxy-estradiol-(17 beta) by a S-adenosylmethionine: acceptor-O-methyltransferase of rat liver].
Topics: Animals; Biochemical Phenomena; Estradiol; Liver; Methionine; Methylation; Methyltransferases; Nucleosides; Nucleotides; Rats; S-Adenosylmethionine; Transferases | 1962 |
The stability of S-adenosylmethionine iodide.
Topics: Iodides; Methionine; S-Adenosylmethionine | 1961 |
Accumulation of S-adenosylmethionine by microorganisms.
Topics: Deoxyadenosines; Escherichia coli; Methionine; Oregon; Pseudomonas; S-Adenosylmethionine; Saccharomyces cerevisiae; Thionucleosides; Yeasts | 1962 |
Utilization of S-adenosylmethionine by micro-organisms.
Topics: Adenine; Bacteria; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur | 1962 |
Spheroplasts of the yeast Candida utilis.
Topics: Candida; Cell Wall; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae; Spheroplasts; Yeasts | 1961 |
S-Methylmethionine- and S-adenosylmethionine-homocysteine transmethylase in higher plant seeds.
Topics: Homocysteine S-Methyltransferase; Methionine; S-Adenosylmethionine; Seeds; Transferases; Vitamin U | 1961 |
Biosynthesis of methionine from S-adenosylmethionine in Escherichia coli.
Topics: Escherichia coli; Methionine; Nucleosides; S-Adenosylmethionine | 1962 |
Utilization of S-adenosylmethionine for the biosynthesis of methionine.
Topics: Enterobacter aerogenes; Methionine; S-Adenosylmethionine | 1963 |
Biosynthesis of S-adenosylmethionine by Saccharomyces cerevisiae. I. Adenine and methionine requirments.
Topics: Adenine; Adenosine; Guanine; Methionine; Naphthalenes; S-Adenosylmethionine; Saccharomyces cerevisiae; Sulfonamides; Yeasts | 1962 |
ASSAY OF TISSUE LEVELS OF S-ADENOSYLMETHIONINE.
Topics: Adrenal Glands; Biochemical Phenomena; Biochemistry; Brain; Chemistry Techniques, Analytical; Kidney; Liver; Lung; Methionine; Myocardium; Nucleosides; Research; S-Adenosylmethionine; Spleen | 1963 |
METABOLISM OF METHIONINE AND S-ADENOSYLMETHIONINE IN NEUROSPORA. ANL-6723.
Topics: Metabolism; Methionine; Neurospora; Nucleosides; Research; S-Adenosylmethionine | 1963 |
ALKALINE HYDROLYSIS OF S-ADENOSYLMETHIONINE IN TRITIATED WATER. ANL-6723.
Topics: Chemical Phenomena; Chemistry; Hydrolysis; Methionine; Nucleosides; S-Adenosylmethionine; Tritium; Water | 1963 |
INDUCTION OF THE METHIONINE-ACTIVATING ENZYME IN SACCHAROMYCES CEREVISIAE.
Topics: Biological Assay; Enterococcus faecalis; Enzymes; Methionine; Oregon; Research; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Yeasts | 1964 |
BIOSYNTHESIS OF METHIONINE IN SACCHAROMYCES CEREVISIAE; PARTIAL PURIFICATION AND PROPERTIES OF S-ADENOSYLMETHIONINE: HOMOCYSTEINE METHYLTRANSFERASE. ANL-6823.
Topics: Carbon Isotopes; Chromatography; Homocysteine; Homocysteine S-Methyltransferase; Metabolism; Methionine; Research; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Sulfur Isotopes; Toluene; Transferases | 1964 |
BIOSYNTHESIS OF METHIONINE IN SACCHAROMYCES CEREVISIAE. PARTIAL PURIFICATION AND PROPERTIES OF S-ADENOSYLMETHIONINE: HOMOCYSTEINE METHYLTRANSFERASE.
Topics: Amino Acids; Chromatography; Homocysteine; Homocysteine S-Methyltransferase; Methionine; Nucleosides; Research; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Transferases | 1964 |
S-ADENOSYLMETHIONINE IN SKIN.
Topics: Animals; Anura; Biomedical Research; Biopsy; Epinephrine; Histocytochemistry; Indoles; Metabolism; Methionine; Norepinephrine; Nucleosides; Pineal Gland; Rats; Research; S-Adenosylmethionine; Serotonin; Skin; Transferases; Vitiligo | 1964 |
ULTRAVIOLET MICROSCOPY OF THE VACUOLE OF SACCHAROMYCES CEREVISIAE DURING SPORULATION.
Topics: Cell Division; Chromatography; Culture Media; Methionine; Microscopy; Microscopy, Ultraviolet; Nucleic Acids; Pharmacology; Research; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Spores; Spores, Fungal; Vacuoles | 1964 |
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. IX. TRANSMETHYLATION FROM S-ADENOSYLMETHIONINE AND 5-METHYLTETRAHYDROFOLATE TO 2-MERCAPTOETHANOL AND HOMOCYSTEINE.
Topics: Alkylation; Biological Assay; Carbon Isotopes; Folic Acid; Homocysteine; Kinetics; Lactobacillus; Mercaptoethanol; Methionine; Nucleosides; Research; S-Adenosylmethionine; Spectrophotometry; Sulfhydryl Compounds; Tetrahydrofolates; Transferases | 1965 |
BIOSYNTHESIS OF METHIONINE IN SACCHAROMYCES CEREVISIAE. KINETICS AND MECHANISM OF REACTION OF S-ADENOSYLMETHIONINE:HOMOCYSTEINE METHYLTRANSFERASE.
Topics: Amino Acids; Chromatography; Homocysteine; Homocysteine S-Methyltransferase; Ions; Kinetics; Mercaptoethanol; Methionine; Nucleosides; Research; S-Adenosylmethionine; Saccharomyces; Saccharomyces cerevisiae; Sulfhydryl Compounds; Transferases | 1965 |
ADENOSYLMETHIONINE ELEVATION IN LEUKEMIC WHITE BLOOD CELLS.
Topics: Antimetabolites; Biochemical Phenomena; Biochemistry; Drug Therapy; Humans; Leukemia; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Lymphocytes; Methionine; Nucleosides; S-Adenosylmethionine; Vitamin B 12 | 1965 |
S-Adenosylmethionine requirement for plant transmethylations.
Topics: Methionine; Plants; S-Adenosylmethionine | 1960 |
S-Adenosylmethionine formation by barley extracts.
Topics: Biochemical Phenomena; Edible Grain; Hordeum; Methionine; Nucleosides; Nucleotides; S-Adenosylmethionine | 1960 |
Assay of S-methylmethionine and S-adenosylmethionine homocysteine transmethylases.
Topics: Biological Assay; Homocysteine S-Methyltransferase; Humans; Methionine; S-Adenosylmethionine; Transferases; Vitamin U | 1959 |
The alkaline hydrolysis of S-adenosylmethionine in tritiated water.
Topics: Hydrolysis; Methionine; Nucleosides; Nucleotides; S-Adenosylmethionine; Tritium; Water | 1962 |
A mathematical model of the methionine cycle.
Topics: Animals; Computational Biology; Cystathionine; Homocysteine; Methionine; Models, Biological; S-Adenosylhomocysteine; S-Adenosylmethionine | 2004 |
Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.
Topics: Amino Acids, Sulfur; Carcinoma; Cell Line, Tumor; Cell Survival; Cystathionine; Cysteine; DNA; Glutathione; Humans; Lung Neoplasms; Methionine; Nicotiana; S-Adenosylhomocysteine; S-Adenosylmethionine; Smoke; Time Factors | 2004 |
Crystal structure and mechanism of a bacterial fluorinating enzyme.
Topics: Catalysis; Crystallization; Crystallography, X-Ray; Deoxyadenosines; Fluorine; Methionine; Models, Molecular; Molecular Sequence Data; Pentosyltransferases; Protein Conformation; S-Adenosylmethionine; Streptomyces | 2004 |
Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of S-adenosylmethionine synthesis from ATP and Met.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Escherichia coli Proteins; Hydrogen Bonding; Liver; Methionine; Methionine Adenosyltransferase; Protein Structure, Tertiary; Rats; S-Adenosylmethionine; Substrate Specificity | 2004 |
Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol.
Topics: Arabidopsis; Blotting, Western; Chloroplasts; Cloning, Molecular; Cytosol; Diffusion; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Green Fluorescent Proteins; Homocysteine; Immunoblotting; Kinetics; Luminescent Proteins; Methionine; Mitochondria; Models, Biological; Molecular Sequence Data; Phylogeny; Pisum sativum; Plastids; Protein Isoforms; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 2004 |
Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine.
Topics: Animals; Cells, Cultured; Chlorocebus aethiops; COS Cells; Deoxyadenosines; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; E1A-Associated p300 Protein; Kupffer Cells; Lipopolysaccharides; Methionine; NF-kappa B; Nuclear Proteins; Promoter Regions, Genetic; Protein-Arginine N-Methyltransferases; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylmethionine; Thionucleosides; Time Factors; Trans-Activators; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2004 |
Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.
Topics: Acetyl Coenzyme A; Acetyltransferases; Adenosylmethionine Decarboxylase; Carcinoma; Cell Division; Deoxyadenosines; Eflornithine; Enzyme Inhibitors; Humans; Male; Methionine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Prostatic Neoplasms; Putrescine; RNA, Messenger; S-Adenosylmethionine; Tetracyclines; Thionucleosides; Tumor Cells, Cultured | 2004 |
NMR regulatory analysis: determination and characterization of S-adenosyl-L-methionine in dietary supplements.
Topics: Adenine; Adenosine; Deuterium Oxide; Dietary Supplements; Magnetic Resonance Spectroscopy; Methionine; Reference Standards; S-Adenosylmethionine; Stereoisomerism; United States | 2004 |
Comparative genomics of the methionine metabolism in Gram-positive bacteria: a variety of regulatory systems.
Topics: Base Sequence; Biological Transport; Gene Expression Regulation, Bacterial; Genome, Bacterial; Genomics; Gram-Positive Bacteria; Methionine; Molecular Sequence Data; Phylogeny; Regulatory Sequences, Ribonucleic Acid; Regulon; RNA, Bacterial; S-Adenosylmethionine; Sodium-Hydrogen Exchangers; Streptococcaceae | 2004 |
Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.
Topics: Alkylating Agents; Biotransformation; Chalcogens; Cysteine; Escherichia coli; Humans; Methionine; Methionine Adenosyltransferase; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Protons; S-Adenosylmethionine; Selenocysteine; Selenomethionine; Stereoisomerism; Substrate Specificity; Sulfonium Compounds; Tellurium | 2004 |
Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase.
Topics: Catalysis; Catechol O-Methyltransferase; Chelating Agents; Cyclopropanes; Deuterium Exchange Measurement; Escherichia coli Proteins; Fatty Acids; Kinetics; Metals, Heavy; Methionine; Methyltransferases; Models, Chemical; Phospholipids; Protons; S-Adenosylmethionine; Selenomethionine; Spectrophotometry, Ultraviolet; Substrate Specificity; Tellurium | 2004 |
Polyamine synthesis from proline in the developing porcine placenta.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amniotic Fluid; Animals; Arginase; Carbon Radioisotopes; Female; Fetal Development; Male; Methionine; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Placenta; Placentation; Polyamines; Pregnancy; Proline; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Sus scrofa | 2005 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
The effect of methionine and S-adenosylmethionine on S-adenosylmethionine levels in the rat brain.
Topics: Administration, Oral; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Combinations; Male; Methionine; Rats; Rats, Long-Evans; S-Adenosylmethionine | 2005 |
A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes.
Topics: Animals; Betaine; Disease Models, Animal; Ethanol; Fatty Liver; Hepatocytes; Male; Methionine; Methyltransferases; Microsomes, Liver; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylmethionine | 2005 |
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.
Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Blotting, Western; Cell Adhesion Molecules, Neuronal; Chromosome Mapping; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsy; Extracellular Matrix Proteins; Frontal Lobe; GABA Modulators; Histones; Imidazoles; Immunohistochemistry; Interpersonal Relations; Male; Methionine; Methylation; Mice; Motor Activity; Nerve Tissue Proteins; Neural Inhibition; Promoter Regions, Genetic; Reelin Protein; Reflex, Startle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Schizophrenia; Serine Endopeptidases; Time Factors; Valproic Acid | 2005 |
MTX-induced white matter changes are associated with polymorphisms of methionine metabolism.
Topics: Aged; Brain; Central Nervous System Neoplasms; Demyelinating Diseases; DNA Mutational Analysis; Drug Resistance; Female; Folic Acid; Folic Acid Antagonists; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Haplotypes; Humans; Lymphoma; Male; Methionine; Methotrexate; Middle Aged; Myelin Sheath; Nerve Fibers, Myelinated; Neurotoxins; Polymorphism, Genetic; Risk Factors; S-Adenosylmethionine | 2005 |
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis.
Topics: Analysis of Variance; Animals; Bile Ducts; Cholestasis; Cysteine; Glutathione; Homocysteine; Ligation; Liver; Liver Cirrhosis, Biliary; Male; Methionine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2005 |
Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine.
Topics: Animals; Cytochrome P-450 CYP2E1 Inhibitors; Cytochromes b5; Kinetics; Male; Methionine; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2005 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Expression of iron-acquisition-related genes in iron-deficient rice is co-ordinately induced by partially conserved iron-deficiency-responsive elements.
Topics: Blotting, Northern; Conserved Sequence; Enzymes; Expressed Sequence Tags; Genes, Plant; Iron; Iron Chelating Agents; Iron Deficiencies; Methionine; Oligonucleotide Array Sequence Analysis; Oryza; Plant Proteins; RNA, Messenger; RNA, Plant; S-Adenosylmethionine | 2005 |
Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice.
Topics: Amino Acids, Sulfur; Animals; Betaine; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Glutathione; Kidney; Lipotropic Agents; Liver; Male; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred ICR; S-Adenosylmethionine; Solvents; Taurine | 2005 |
Dietary S-methylmethionine, a component of foods, has choline-sparing activity in chickens.
Topics: Animals; Chickens; Choline; Diet; Male; Methionine; S-Adenosylmethionine; Vitamin U | 2005 |
Effect of fasting on methionine adenosyltransferase expression and the methionine cycle in the mouse liver.
Topics: Animals; DNA Methylation; Fasting; Gene Expression; Glutathione; Kinetics; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Mice; RNA, Messenger; S-Adenosylmethionine | 2005 |
Diet-dependent survival of protein repair-deficient mice.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Brain; Eating; Folic Acid; Methionine; Mice; Mice, Mutant Strains; Protein D-Aspartate-L-Isoaspartate Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures; Survival Rate | 2005 |
The immediate-early ethylene response gene OsARD1 encodes an acireductone dioxygenase involved in recycling of the ethylene precursor S-adenosylmethionine.
Topics: Amino Acid Sequence; Dioxygenases; Ethylenes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Immediate-Early; Genes, Plant; Methionine; Molecular Sequence Data; Oryza; S-Adenosylmethionine; Sequence Homology, Amino Acid; Water | 2005 |
Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biomarkers; Choline; Chromatography, High Pressure Liquid; Disease Models, Animal; Fatty Liver; Female; Hepatitis; Heterozygote; Methionine; Mice; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Severity of Illness Index; Up-Regulation | 2006 |
Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic-Leucine Zipper Transcription Factors; Cell Nucleus; Chromosomal Instability; Cysteine; F-Box Proteins; Gene Expression Regulation, Fungal; Kinetochores; Methionine; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Repressor Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur; Transcription, Genetic; Ubiquitin; Ubiquitin-Protein Ligase Complexes | 2006 |
Glutathione-enhancing agents protect against steatohepatitis in a dietary model.
Topics: Animals; Choline; Cytokines; Disease Models, Animal; Fatty Liver; Food, Formulated; Inflammation; Lipotropic Agents; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Thiazoles; Transaminases | 2006 |
[Effect of feeding pre-L-methionine on high-cell-density fermentation for S-adenosyl-L-methionine production].
Topics: Bioreactors; Cell Culture Techniques; Culture Media; Fermentation; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae | 2006 |
S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.
Topics: Allosteric Regulation; Animals; Carcinoma, Hepatocellular; Cell Line; Cystathionine beta-Synthase; Enzyme Stability; Fatty Liver; Gene Silencing; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Knockout; Oxidation-Reduction; Recombinant Proteins; S-Adenosylmethionine | 2006 |
In vivo hydrolysis of S-adenosylmethionine induces the met regulon of Escherichia coli.
Topics: Artificial Gene Fusion; Bacteriophage T3; beta-Galactosidase; DNA Transposable Elements; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Reporter; Hydrolases; Hydrolysis; Methionine; Mutagenesis, Insertional; Plasmids; Regulon; S-Adenosylmethionine; Transformation, Bacterial; Viral Proteins | 2006 |
The 5th workshop on the assessment of adequate intake of dietary amino acids: general discussion 1.
Topics: Amino Acids; Animals; Creatine; Cysteine; Diet; Glutathione; Homocysteine; Humans; Methionine; Nutritional Requirements; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
In vivo hydrolysis of S-adenosyl-L-methionine in Escherichia coli increases export of 5-methylthioribose.
Topics: Biological Transport; Escherichia coli; Hydrolases; Hydrolysis; Methionine; Plasmids; S-Adenosylmethionine; Thioglycosides; Transformation, Bacterial | 2006 |
Structure of the S-adenosylmethionine riboswitch regulatory mRNA element.
Topics: Azoarcus; Base Sequence; Binding Sites; Crystallography, X-Ray; Gene Expression Regulation, Bacterial; Introns; Ligands; Methionine; Models, Molecular; Nucleic Acid Conformation; RNA, Bacterial; RNA, Messenger; S-Adenosylmethionine; Static Electricity; Sulfur; Thermoanaerobacter | 2006 |
Modulation of DNA methyltransferase profile by methyl donor starvation followed by gamma irradiation.
Topics: Animals; Cell Nucleus; Choline; Comet Assay; Cytoplasm; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; DNA Repair; Dose-Response Relationship, Radiation; Folic Acid; Gamma Rays; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; S-Adenosylmethionine | 2007 |
Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats.
Topics: Adenine; Animals; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Enzyme Activation; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2006 |
Folate, the methionine cycle, and Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Reactive Oxygen Species; S-Adenosylmethionine | 2006 |
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.
Topics: Adolescent; Autistic Disorder; Catechol O-Methyltransferase; Child; Child, Preschool; DNA Primers; Female; Gene Frequency; Glutathione Transferase; Humans; Male; Membrane Transport Proteins; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidative Stress; Reduced Folate Carrier Protein; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins | 2006 |
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2006 |
Tandem riboswitch architectures exhibit complex gene control functions.
Topics: 5' Untranslated Regions; Aptamers, Nucleotide; Bacillus; Base Sequence; Cobamides; Gene Expression Regulation, Bacterial; Genes, Bacterial; Ligands; Methionine; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Bacterial; RNA, Messenger; S-Adenosylmethionine; Transcription, Genetic | 2006 |
The role of methionine recycling for ethylene synthesis in Arabidopsis.
Topics: Adenosine Triphosphate; Arabidopsis; Ethylenes; Gene Expression Regulation, Plant; Methionine; Models, Biological; Mutation; Phenotype; Plant Proteins; Plants, Genetically Modified; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Sulfur | 2007 |
Recognition of age-damaged (R,S)-adenosyl-L-methionine by two methyltransferases in the yeast Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Animals; Arabidopsis; Caenorhabditis elegans; Drosophila melanogaster; Homocysteine; Homocysteine S-Methyltransferase; Kinetics; Methionine; Methyltransferases; Mice; Molecular Sequence Data; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.
Topics: Animals; Brain; Disease Models, Animal; Embryo, Mammalian; Female; Ferredoxin-NADP Reductase; Folic Acid; Heart; Homocysteine; Hyperhomocysteinemia; Kidney; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: Adolescent; Adult; Betaine; Brain; Brain Diseases; Child; Child, Preschool; Humans; Infant, Newborn; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mutation, Missense; Neonatal Screening; S-Adenosylmethionine | 2007 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2007 |
Supranormal dietary folic acid supplementation: effects on methionine metabolism in weanling rats.
Topics: Animals; Biomarkers; Dietary Supplements; DNA Methylation; Folic Acid; Homocysteine; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamins; Weaning | 2007 |
S-adenosylmethionine attenuates hepatic lipid synthesis in micropigs fed ethanol with a folate-deficient diet.
Topics: Adiponectin; AMP-Activated Protein Kinase Kinases; Animals; Down-Regulation; Enzyme Activation; Ethanol; Fatty Liver, Alcoholic; Feeding Behavior; Folic Acid Deficiency; Food, Formulated; Intra-Abdominal Fat; Lipids; Lipogenesis; Liver; Methionine; Nutritional Support; Omentum; Protein Kinases; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1; Swine; Swine, Miniature | 2007 |
S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet.
Topics: Animals; Body Weight; Disease Models, Animal; Ethanol; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Linear Models; Liver; Liver Diseases, Alcoholic; Male; Methionine; Necrosis; Oxidative Stress; S-Adenosylmethionine; Swine; Swine, Miniature | 2007 |
Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.
Topics: Alanine Transaminase; Animals; ATPases Associated with Diverse Cellular Activities; Chromosome Mapping; Disease Models, Animal; Down-Regulation; Embryo, Mammalian; Female; Gene Expression; Gene Expression Profiling; Glycine N-Methyltransferase; Glycogen; Glycogen Storage Disease; Hepatitis, Chronic; Homocysteine; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Metabolic labeling of prenyl and carboxyl-methyl groups.
Topics: Animals; Cells, Cultured; Humans; Indicators and Reagents; Isotope Labeling; Methionine; Methylation; Mevalonic Acid; Protein O-Methyltransferase; Protein Prenylation; Protein Processing, Post-Translational; Proteins; S-Adenosylmethionine; Tritium | 2001 |
The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet.
Topics: Animals; Choline; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Food, Formulated; Glutathione; Hepatitis; Homeostasis; Lipid Metabolism; Liver; Methionine; Mice; Mice, Mutant Strains; Mice, Obese; Obesity; S-Adenosylmethionine | 2008 |
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
Topics: Animals; Carcinoma, Hepatocellular; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Glycine N-Methyltransferase; Histones; Janus Kinases; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice; Mice, Knockout; Promoter Regions, Genetic; ras Proteins; S-Adenosylmethionine; Signal Transduction; STAT Transcription Factors; Suppressor of Cytokine Signaling Proteins; Transaminases; Tumor Suppressor Proteins | 2008 |
Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling.
Topics: 5' Untranslated Regions; Base Sequence; Binding Sites; Coenzymes; Conserved Sequence; Gene Expression Regulation; Homocysteine; Kinetics; Methionine; Nucleic Acid Conformation; RNA; RNA, Bacterial; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
An allosteric mechanism for switching between parallel tracks in mammalian sulfur metabolism.
Topics: Animals; Cells, Cultured; Computer Simulation; Hepatocytes; Metabolic Clearance Rate; Methionine; Mice; Models, Biological; S-Adenosylmethionine | 2008 |
Crystal structures of human 108V and 108M catechol O-methyltransferase.
Topics: Binding Sites; Catechol O-Methyltransferase; Catechols; Crystallography, X-Ray; Cysteine; Humans; Methionine; Models, Molecular; Mutant Proteins; Polymorphism, Single Nucleotide; Protein Structure, Secondary; S-Adenosylmethionine; Valine | 2008 |
Taurine supplementation improves the utilization of sulfur-containing amino acids in rats continually administrated alcohol.
Topics: Alcohol Drinking; Animals; Cysteine; Ethanol; Methionine; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine | 2009 |
Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy.
Topics: Bacillus; Bacterial Proteins; Chromatography, High Pressure Liquid; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Hexosamines; Iron; Methionine; Models, Molecular; Molecular Structure; Oxidoreductases; Protein Binding; S-Adenosylmethionine; Sulfur | 2008 |
Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet.
Topics: Animals; Brain; Diet, Reducing; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Folic Acid Deficiency; Homocysteine; Male; Methionine; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Regulatory Factor X Transcription Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Transcription Factors | 2008 |
Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Survival; Disease Models, Animal; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Humans; Jurkat Cells; Leukemia; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; RNA Interference; S-Adenosylmethionine | 2008 |
S-adenosylmethionine and proliferation: new pathways, new targets.
Topics: AMP-Activated Protein Kinases; Animals; Antigens, Surface; Cell Proliferation; Disease Models, Animal; ELAV Proteins; ELAV-Like Protein 1; Hepatocytes; Humans; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; Multienzyme Complexes; Protein Serine-Threonine Kinases; RNA-Binding Proteins; S-Adenosylmethionine; Signal Transduction | 2008 |
Methionine metabolism in an animal model of sepsis.
Topics: Animals; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Lipopolysaccharides; Male; Methionine; Oxidation-Reduction; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis | 2008 |
Requirement of RIZ1 for cancer prevention by methyl-balanced diet.
Topics: Animals; Diet; DNA-Binding Proteins; Food; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Methionine; Methylation; Mice; Mice, Knockout; Neoplasms; Nuclear Proteins; S-Adenosylmethionine; Transcription Factors | 2008 |
Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells.
Topics: Cell Line; Cells, Cultured; Disulfides; Epithelial Cells; Humans; Lung; Metabolic Networks and Pathways; Methionine; Methylation; Methyltransferases; Models, Biological; Oxidation-Reduction; Oxidative Stress; Peroxides; Respiratory Mucosa; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine.
Topics: Animals; Brain; Cognition Disorders; Dietary Supplements; Folic Acid Deficiency; Homocystine; Lecithins; Male; Maze Learning; Methionine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone.
Topics: Aged; Animals; Bone and Bones; Collagen; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methionine; Myocardium; Osteoporosis; Porosity; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Stress, Mechanical | 2009 |
Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation.
Topics: Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Folic Acid; Glucose; Homocysteine; Humans; Insulin; Methionine; Methylation; S-Adenosylmethionine; Sulfur | 2009 |
[Pre-L-methionine feeding strategy for S-adenosyl-L-methionine fermentative production].
Topics: Bioreactors; Fermentation; Methionine; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae | 2008 |
Experimental hyperhomocysteinaemia: differences in tissue metabolites between homocystine and methionine feeding in a rat model.
Topics: Analysis of Variance; Animal Feed; Animals; Cardiovascular Diseases; Dietary Supplements; Disease Models, Animal; Female; Homocystine; Hyperhomocysteinemia; Kidney; Liver; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Statistics, Nonparametric; Tissue Distribution | 2009 |
Optimization of L: -methionine feeding strategy for improving S-adenosyl-L: -methionine production by methionine adenosyltransferase overexpressed Pichia pastoris.
Topics: Adenosine Triphosphate; Citric Acid Cycle; Glycolysis; Methionine; Methionine Adenosyltransferase; Pichia; S-Adenosylmethionine | 2009 |
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Cysteine; Dietary Proteins; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Glycine; Homocysteine; Liver; Male; Methionine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Weight Gain | 2009 |
A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme.
Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Cell Line, Tumor; Enzyme Activation; Female; Humans; Melanoma; Methionine; Mice; Mice, Nude; Molecular Sequence Data; Molecular Structure; Neoplasm Invasiveness; Neoplasm Metastasis; Proteomics; rhoA GTP-Binding Protein; RNA Interference; S-Adenosylmethionine; Signal Transduction; Transplantation, Heterologous | 2009 |
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Fatty Liver; Female; Homocysteine; Liver; Liver Neoplasms; Methionine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Unfolded Protein Response | 2009 |
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.
Topics: Adenosine; Base Sequence; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Fatty Acids; Methionine; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; RNA, Ribosomal; RNA, Ribosomal, 16S; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity | 2010 |
Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions.
Topics: Bacterial Proteins; Base Sequence; Consensus Sequence; Dimerization; DNA; Fractionation, Field Flow; Kinetics; Methionine; Molecular Weight; Oligodeoxyribonucleotides; Protein Binding; Repressor Proteins; S-Adenosylmethionine; Ultracentrifugation | 2010 |
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.
Topics: Animal Feed; Animals; Ceramides; Choline; Fatty Liver; Glutathione; Inflammation; Lipids; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Prodrugs; S-Adenosylmethionine; Sphingomyelin Phosphodiesterase | 2010 |
Global DNA methylation in the mouse liver is affected by methyl deficiency and arsenic in a sex-dependent manner.
Topics: Animals; Arsenites; Carcinogens; Choline Deficiency; Deoxycytidine; Diet; DNA; DNA Methylation; DNA Modification Methylases; Female; Folic Acid Deficiency; Gene Expression Regulation, Enzymologic; Isoenzymes; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Sodium Compounds | 2011 |
Some more comments on 'folate deficiency in chronic pancreatitis'.
Topics: Folic Acid Deficiency; Glycine N-Methyltransferase; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Pancreatitis, Chronic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Radical SAM activation of the B12-independent glycerol dehydratase results in formation of 5'-deoxy-5'-(methylthio)adenosine and not 5'-deoxyadenosine.
Topics: Catalysis; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Enzyme Activation; Free Radicals; Glycine; Hydro-Lyases; Methionine; Oxidation-Reduction; S-Adenosylmethionine; Thionucleosides; Vitamin B 12 | 2011 |
A high-throughput absorbance-based assay for methionine produced by methionine aminopeptidase using S-adenosyl-L-methionine synthetase.
Topics: Aminopeptidases; Cations, Divalent; Drug Discovery; Edetic Acid; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; High-Throughput Screening Assays; Kinetics; Ligases; Manganese; Methionine; Methionyl Aminopeptidases; Reference Standards; S-Adenosylmethionine | 2011 |
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
The effects of dietary supplementation of methionine on genomic stability and p53 gene promoter methylation in rats.
Topics: Animals; Dietary Supplements; DNA Methylation; Doxorubicin; Genes, p53; Genomic Instability; Glutathione; Kidney; Male; Methionine; Promoter Regions, Genetic; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes in Plantago and Arabidopsis.
Topics: Aldose-Ketose Isomerases; Alkenes; Arabidopsis; Arabidopsis Proteins; Azetidinecarboxylic Acid; Deoxyadenosines; Ethylenes; Gene Expression Regulation, Plant; Genes, Reporter; Methionine; Phloem; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Plant Growth Regulators; Plant Leaves; Plant Proteins; Plant Vascular Bundle; Plantago; Polyamines; RNA, Messenger; RNA, Plant; S-Adenosylmethionine; Thionucleosides; Transcriptome; Yeasts | 2011 |
Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.
Topics: Adenosine; Drug Design; Enzyme Inhibitors; Escherichia coli Proteins; Methane; Methionine; Models, Biological; Models, Molecular; Peptide Fragments; Protein Binding; S-Adenosylmethionine; Sequence Homology; Substrate Specificity; tRNA Methyltransferases | 2011 |
[Function of luxS gene in sulfurmetabolism of Streptococcus mutans].
Topics: Bacterial Proteins; Biofilms; Carbon-Sulfur Lyases; Culture Media; Culture Techniques; Cysteine; Gene Expression Regulation, Bacterial; Methionine; Microscopy, Confocal; Quorum Sensing; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptococcus mutans; Sulfur | 2011 |
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cysteine; Diet; Enzyme Inhibitors; Fatty Liver; Glutathione; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 2011 |
Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast.
Topics: Amino Acid Substitution; Basic-Leucine Zipper Transcription Factors; Cell Membrane; Gene Expression Profiling; Gene Expression Regulation, Fungal; Gene Knockout Techniques; Methionine; Methylation; Mutation; Myo-Inositol-1-Phosphate Synthase; Nuclear Proteins; Phospholipids; Polymorphism, Single Nucleotide; Repressor Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur; Transcription, Genetic | 2011 |
Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function.
Topics: Adenosine Kinase; Adult; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Child; Developmental Disabilities; Family Health; Female; Fibroblasts; Homocysteine; Humans; Liver Diseases; Male; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Proteomic analysis of a sea-ice diatom: salinity acclimation provides new insight into the dimethylsulfoniopropionate production pathway.
Topics: Acclimatization; Adenosylhomocysteinase; Diatoms; Electrophoresis, Gel, Two-Dimensional; Ice Cover; Methionine; Methionine Adenosyltransferase; Methyltransferases; Photosynthesis; Photosystem II Protein Complex; Phytoplankton; Protein Isoforms; Proteins; Proteomics; S-Adenosylmethionine; Salinity; Sulfonium Compounds | 2011 |
Two patients with hepatic mtDNA depletion syndromes and marked elevations of S-adenosylmethionine and methionine.
Topics: Adolescent; Base Sequence; DNA, Mitochondrial; Exons; Female; Glycine N-Methyltransferase; Humans; Infant; Liver; Male; Membrane Proteins; Methionine; Mitochondrial Diseases; Mitochondrial Proteins; Molecular Sequence Data; Mutation; S-Adenosylmethionine; Sequence Deletion | 2012 |
S-adenosylmethionine treatment in methionine adenosyltransferase deficiency, a case report.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Female; Humans; Methionine; Methionine Adenosyltransferase; Mutation, Missense; S-Adenosylmethionine | 2012 |
Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo.
Topics: Animals; Antirheumatic Agents; Dactinomycin; Dexamethasone; Enzyme Inhibitors; Folic Acid; Gene Expression Regulation; Hep G2 Cells; Humans; Male; Methionine; Methionine Adenosyltransferase; Methotrexate; Mice; Mice, Inbred C57BL; RNA, Messenger; S-Adenosylmethionine | 2012 |
[Induction of endogenous s-adenosyl-l-methionine in hepatocytes during pharmacological correction of experimental acute toxic and chronic drug-induced liver injury].
Topics: Acute Disease; Animals; Animals, Outbred Strains; Antitubercular Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Hepatocytes; Liver; Male; Meglumine; Methionine; Protective Agents; Rats; S-Adenosylmethionine; Succinates; Succinic Acid | 2011 |
Post-translational stabilization of thiopurine S-methyltransferase by S-adenosyl-L-methionine reveals regulation of TPMT*1 and *3C allozymes.
Topics: Cell Culture Techniques; Culture Media; Enzyme Inhibitors; Erythrocytes; Folic Acid; Genotype; HEK293 Cells; Hep G2 Cells; Humans; Isoenzymes; Methionine; Methionine Adenosyltransferase; Methyltransferases; Protein Processing, Post-Translational; Protein Stability; S-Adenosylmethionine | 2012 |
Methionine sulfoxide reductase contributes to meeting dietary methionine requirements.
Topics: Animals; Base Sequence; Diet; DNA Primers; Glycine N-Methyltransferase; Methionine; Methionine Sulfoxide Reductases; Mice; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Computational analysis of cysteine and methionine metabolism and its regulation in dairy starter and related bacteria.
Topics: Bacterial Proteins; Computational Biology; Cysteine; Dairying; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Lactobacillales; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine; Streptococcaceae; Transcription Factors; Transcription, Genetic | 2012 |
[Intrahepatic induction of endogenous S-adenosyl-L-methionine against the background of various ways of administration of methionine-succinate complex and its role in drug-induced liver lesion correction].
Topics: Animals; Liver; Male; Meglumine; Methionine; Protective Agents; Rats; S-Adenosylmethionine; Succinates | 2012 |
Adenosine kinase-deficient mutant of Saccharomyces cerevisiae accumulates S-adenosylmethionine because of an enhanced methionine biosynthesis pathway.
Topics: Adenosine Kinase; Biosynthetic Pathways; Crosses, Genetic; Culture Media; Gene Expression Profiling; Metabolome; Methionine; Microarray Analysis; S-Adenosylmethionine; Saccharomyces cerevisiae | 2013 |
Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation.
Topics: Asian People; Biopsy; Black or African American; Blotting, Western; Folic Acid; Gene Expression Regulation, Enzymologic; Genes, Reporter; Genetic Association Studies; Genomics; Genotype; Glycine N-Methyltransferase; HEK293 Cells; Hep G2 Cells; Humans; Liver; Methionine; Methionine Adenosyltransferase; Phenotype; Polymorphism, Single Nucleotide; S-Adenosylmethionine; Sequence Analysis, DNA; Transfection; White People | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Identification of new ligands for the methionine biosynthesis transcriptional regulator (MetJ) by FAC-MS.
Topics: Adenine; Bacterial Proteins; Binding Sites; Chromatography, Affinity; Cloning, Molecular; Deoxyadenosines; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Vectors; High-Throughput Screening Assays; Ligands; Methionine; Protein Binding; Repressor Proteins; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Thionucleosides; Time Factors; Transcription, Genetic | 2012 |
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult | 2012 |
The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Bacillus cereus; Bacterial Proteins; Biotin; Carrier Proteins; Chromatography, Gel; Conserved Sequence; Escherichia coli; Fatty Acids; Genetic Complementation Test; Hydrogen-Ion Concentration; Methionine; Molecular Sequence Data; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2012 |
The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Cholesterol, Dietary; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression; Homocysteine; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Male; Methionine; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2012 |
RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins.
Topics: Cloning, Molecular; Deoxyadenosines; Escherichia coli; Escherichia coli Proteins; Free Radicals; Gene Expression; Iron; Iron-Sulfur Proteins; Klebsiella pneumoniae; Methionine; Methyltransferases; Models, Chemical; S-Adenosylmethionine; Spectroscopy, Mossbauer | 2012 |
Elevation of cysteine consumption in tamoxifen-resistant MCF-7 cells.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione; Humans; Membrane Transport Modulators; Methionine; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Tamoxifen; Taurine; Up-Regulation | 2013 |
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins | 2013 |
Downregulation of Cdc6 and pre-replication complexes in response to methionine stress in breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Chromatin; Cyclin-Dependent Kinase 2; Down-Regulation; Female; G1 Phase Cell Cycle Checkpoints; Homocysteine; Humans; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Methionine; Multiprotein Complexes; Nuclear Proteins; Phosphorylation; Proteins; Proto-Oncogene Proteins c-akt; S-Adenosylmethionine; TOR Serine-Threonine Kinases | 2012 |
Hepatic metabolism of sulfur amino acids in db/db mice.
Topics: Amino Acids, Sulfur; Animals; Betaine-Homocysteine S-Methyltransferase; Cysteine; Cysteine Dioxygenase; Diabetes Mellitus, Experimental; Dipeptides; Glutathione; Homocysteine; Ligases; Lipid Peroxidation; Liver; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Putrescine; Receptors, Leptin; S-Adenosylmethionine; Spermidine; Taurine; Triglycerides; Up-Regulation | 2013 |
LC-MS/MS identification of the one-carbon cycle metabolites in human plasma.
Topics: Adult; Chromatography, Liquid; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Multiple Sclerosis; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2013 |
Evolution of Sindbis virus with a low-methionine-resistant phenotype is dependent both on a pre-existing mutation and on the methionine concentration in the medium.
Topics: Aedes; Amino Acids; Animals; Codon; Culture Media; Directed Molecular Evolution; Drug Resistance, Viral; Luciferases; Methionine; Mutant Proteins; Mutation; S-Adenosylmethionine; Serial Passage; Sindbis Virus; Viral Load | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Methylation metabolites in amniotic fluid depend on gestational age.
Topics: Adult; Amniotic Fluid; Betaine; Choline; Female; Gestational Age; Humans; Methionine; Methylation; Methyltransferases; Pregnancy; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine | 2013 |
The catalytic mechanism for aerobic formation of methane by bacteria.
Topics: Aerobiosis; Archaea; Bacteria; Bacterial Proteins; Biocatalysis; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Glycine; Hydrogen; Lyases; Mass Spectrometry; Methane; Methionine; Mutant Proteins; Pentosephosphates; S-Adenosylmethionine | 2013 |
Methionine inhibits autophagy and promotes growth by inducing the SAM-responsive methylation of PP2A.
Topics: Autophagy; Intracellular Signaling Peptides and Proteins; Methionine; Methylation; Protein Methyltransferases; Protein Phosphatase 2; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2013 |
Cell division, one-carbon metabolism and methionine synthesis in a metK-deficient Escherichia coli mutant, and a role for MmuM.
Topics: Carbon; Cell Division; Culture Media; Escherichia coli K12; Escherichia coli Proteins; Glucose; Homocysteine S-Methyltransferase; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 2013 |
Nutritional control of epigenetic processes in yeast and human cells.
Topics: Epigenesis, Genetic; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Histones; Humans; Infant, Newborn; K562 Cells; Methionine; Methylation; Neural Tube Defects; Pregnancy; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Species Specificity | 2013 |
Levels of key enzymes of methionine-homocysteine metabolism in preeclampsia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Female; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two Caucasian populations.
Topics: Adipose Tissue; Aged; Aged, 80 and over; Amino Acids, Sulfur; Cohort Studies; Cross-Sectional Studies; Cystathionine; Cysteine; Diet; Dipeptides; Exercise; Fatty Acids; Female; Glutathione; Homocysteine; Humans; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Stearoyl-CoA Desaturase; Surveys and Questionnaires; White People | 2013 |
Expression, purification, and characterization of a recombinant methionine adenosyltransferase pDS16 in Pichia pastoris.
Topics: Adenosine Triphosphate; DNA Shuffling; Escherichia coli; Gene Expression Regulation, Fungal; Kinetics; Methionine; Methionine Adenosyltransferase; Pichia; Recombinant Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Streptomycetaceae | 2014 |
S-adenosylmethionine limitation induces p38 mitogen-activated protein kinase and triggers cell cycle arrest in G1.
Topics: B-Lymphocytes; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; DNA Methylation; Epigenesis, Genetic; G1 Phase; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Mechanistic Target of Rapamycin Complex 1; Methionine; Methionine Adenosyltransferase; Mitogen-Activated Protein Kinase 14; Multiprotein Complexes; Phosphorylation; Protein Serine-Threonine Kinases; S-Adenosylmethionine; Signal Transduction; TOR Serine-Threonine Kinases | 2014 |
Methionine is a signal of amino acid sufficiency that inhibits autophagy through the methylation of PP2A.
Topics: Animals; Autophagy; Methionine; Methylation; Protein Phosphatase 2; S-Adenosylmethionine | 2014 |
Genetic variants of homocysteine metabolism and multiple sclerosis: a case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Case-Control Studies; Cystathionine beta-Synthase; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multiple Sclerosis; Polymorphism, Genetic; S-Adenosylmethionine | 2014 |
[Pharmacological activity of runihol and S-adenosyl-L-methionine in rats with experimental liver damage by reserve antituberculosis drugs].
Topics: Aminosalicylic Acid; Animals; Animals, Outbred Strains; Antitubercular Agents; Bilirubin; Chemical and Drug Induced Liver Injury; Cholesterol; Cycloserine; Hepatocytes; Inosine; Liver; Male; Methionine; Protective Agents; Prothionamide; Rats; S-Adenosylmethionine; Succinic Acid; Taurine; Triglycerides | 2013 |
A halt in poly(A) shortening during S-adenosyl-L-methionine-induced translation arrest in CGS1 mRNA of Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Carbon-Oxygen Lyases; Gene Expression Regulation, Plant; Genes, Plant; Methionine; Mutation; Poly A; Ribonuclease H; RNA Stability; RNA, Messenger; RNA, Plant; S-Adenosylmethionine | 2013 |
In vitro characterization of uptake mechanism of L-[methyl-(3)H]-methionine in hepatocellular carcinoma.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Cell Cycle; Cell Line, Tumor; Cell Survival; Liver Neoplasms; Methionine; Mice; Phosphatidylethanolamine N-Methyltransferase; Radionuclide Imaging; S-Adenosylmethionine; Transfection | 2014 |
Interspecies systems biology uncovers metabolites affecting C. elegans gene expression and life history traits.
Topics: Animals; Betaproteobacteria; Caenorhabditis elegans; Diet; Escherichia coli; Gene Expression Regulation; Metabolic Networks and Pathways; Methionine; Molecular Sequence Data; Propionates; S-Adenosylmethionine; Transcriptome; Vitamin B 12 | 2014 |
Multiple inputs control sulfur-containing amino acid synthesis in Saccharomyces cerevisiae.
Topics: Basic-Leucine Zipper Transcription Factors; Cysteine; F-Box Proteins; Gene Expression Regulation, Fungal; Green Fluorescent Proteins; Methionine; Methionine Adenosyltransferase; Methylation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin-Protein Ligase Complexes; Ubiquitination | 2014 |
Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Cognition; Cyclin E; Fibroblast Growth Factor 2; Gene Expression Regulation; Glycine N-Methyltransferase; Hippocampus; MAP Kinase Signaling System; Maze Learning; Memory Disorders; Methionine; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurogenesis; Neuronal Plasticity; Rotarod Performance Test; S-Adenosylmethionine | 2014 |
Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse.
Topics: Animals; Betaine; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Ethanol; Fatty Liver, Alcoholic; Gene Expression Regulation; Homocystinuria; Liver; Methionine; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; PPAR alpha; S-Adenosylhomocysteine; S-Adenosylmethionine | 2014 |
Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Homeodomain Proteins; Humans; Induced Pluripotent Stem Cells; Methionine; Nanog Homeobox Protein; p38 Mitogen-Activated Protein Kinases; S-Adenosylmethionine; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult | 2014 |
Evidence that glutamine transaminase and omega-amidase potentially act in tandem to close the methionine salvage cycle in bacteria and plants.
Topics: Amidohydrolases; Arabidopsis; Bacillus subtilis; Ketoglutaric Acids; Lyases; Methionine; Poaceae; S-Adenosylmethionine; Solanaceae; Solanum lycopersicum; Transaminases; Zea mays | 2015 |
Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Dihydropteroate Synthase; Drug Evaluation, Preclinical; Drug Synergism; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Bacterial; Humans; Methionine; Mycobacterium tuberculosis; S-Adenosylmethionine; Species Specificity; Tetrahydrofolate Dehydrogenase; Triazines | 2014 |
Methionine deficiency does not increase polyamine turnover through depletion of hepatic S-adenosylmethionine in juvenile Atlantic salmon.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Aquaculture; Deficiency Diseases; Diet; Energy Intake; Fish Proteins; Gene Expression Regulation, Developmental; Lipid Metabolism; Liver; Methionine; Muscle, Skeletal; Norway; Ornithine Decarboxylase; Plant Proteins; Polyamines; Putrescine; S-Adenosylmethionine; Salmo salar; Spermine; Weight Gain | 2014 |
Injury-induced biosynthesis of methyl-branched polyene pigments in a white-rotting basidiomycete.
Topics: Animals; Basidiomycota; Dose-Response Relationship, Drug; Drosophila melanogaster; Electron Spin Resonance Spectroscopy; Humans; K562 Cells; Larva; Methionine; Molecular Structure; Pigments, Biological; Polyenes; S-Adenosylmethionine; Stereoisomerism | 2014 |
Whey protein supplementation increases methionine intake but not homocysteine plasma concentration in rats.
Topics: Advanced Oxidation Protein Products; Animals; Biomarkers; Caseins; Dietary Supplements; Glutathione; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Liver; Male; Methionine; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Random Allocation; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Whey Proteins | 2015 |
L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Dietary Supplements; Energy Intake; Ethanol; Fatty Liver, Alcoholic; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; S-Adenosylmethionine; Serine; Triglycerides | 2015 |
The effect of a methyl-deficient diet on the global DNA methylation and the DNA methylation regulatory pathways.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Choline Deficiency; Cytosine; Deoxyguanosine; DNA Methylation; Fatty Liver; Gene Expression Regulation, Enzymologic; Liver; Male; Methionine; Mice, Inbred C57BL; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Trans-sulfuration Pathway Seleno-amino Acids Are Mediators of Selenomethionine Toxicity in Saccharomyces cerevisiae.
Topics: Amino Acids, Sulfur; Dietary Supplements; DNA Repair; Humans; Metabolic Networks and Pathways; Methionine; Mutation; Oxidative Stress; S-Adenosylmethionine; Saccharomyces cerevisiae; Selenious Acid; Selenium Compounds; Selenocysteine; Selenomethionine | 2015 |
Chemoenzymatic Synthesis of (36)S Isotopologues of Methionine and S-Adenosyl-L-methionine.
Topics: Isotope Labeling; Kinetics; Methionine; Molecular Structure; S-Adenosylmethionine; Sulfur Radioisotopes | 2015 |
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine | 2015 |
Guanidinoacetate is more effective than creatine at enhancing tissue creatine stores while consequently limiting methionine availability in Yucatan miniature pigs.
Topics: Animals; Body Weight; Creatine; Diet; Dietary Supplements; Glycine; Liver; Methionine; Methylation; Muscles; S-Adenosylmethionine; Swine; Swine, Miniature; Tissue Distribution | 2015 |
Substrate-Tuned Catalysis of the Radical S-Adenosyl-L-Methionine Enzyme NosL Involved in Nosiheptide Biosynthesis.
Topics: Catalysis; Methionine; Molecular Structure; S-Adenosylmethionine; Thiazoles | 2015 |
Essential roles of methionine and S-adenosylmethionine in the autarkic lifestyle of Mycobacterium tuberculosis.
Topics: Acetyltransferases; Animals; Cell Line; Female; Humans; Immunocompetence; Metabolome; Methionine; Mice, Inbred C57BL; Mice, SCID; Mycobacterium tuberculosis; S-Adenosylmethionine; Time Factors; Transcriptome; Virulence | 2015 |
GC-TOF-MS-based serum metabolomic investigations of naked oat bran supplementation in high-fat-diet-induced dyslipidemic rats.
Topics: Animals; Arachidonic Acid; Avena; Biomarkers; Biopsy; Diet; Diet, High-Fat; Dietary Fiber; Dyslipidemias; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Hyperlipidemias; Liver; Male; Metabolomics; Methionine; Multivariate Analysis; Oleic Acid; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2015 |
Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.
Topics: Animals; Autophagy; Cell Culture Techniques; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Methionine; Methylation; Mice; Protein Phosphatase 2; S-Adenosylmethionine | 2016 |
Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism.
Topics: Animals; Carbon; Chromatin; Epigenesis, Genetic; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver; Methionine; Methylation; Mice; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Regiocomplementary O-Methylation of Catechols by Using Three-Enzyme Cascades.
Topics: Animals; Archaea; Archaeal Proteins; Catechol O-Methyltransferase; Catechols; Chromatography, High Pressure Liquid; Methionine; Methionine Adenosyltransferase; Methylation; N-Glycosyl Hydrolases; Oxygen; Rats; S-Adenosylmethionine; Spectrophotometry; Stereoisomerism | 2015 |
One of these is not like the others.
Topics: Amino Acids; Humans; Methionine; Mutation; Mycobacterium tuberculosis; S-Adenosylmethionine; Tuberculosis | 2015 |
NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Betaine; Blotting, Western; Cells, Cultured; Cysteine; Female; Glutathione; Hep G2 Cells; Homocysteine; Humans; Immunoenzyme Techniques; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; S-Adenosylmethionine | 2015 |
S-Adenosyl-l-methionine Modulates CO and NO• Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Heme; Humans; Kinetics; Methionine; Nitric Oxide; Oxidation-Reduction; S-Adenosylmethionine | 2016 |
Adenosine kinase deficiency: expanding the clinical spectrum and evaluating therapeutic options.
Topics: Adenosine; Adenosine Kinase; Adolescent; Adult; Biomarkers; Child; Child, Preschool; Diet; Female; Humans; Hypoglycemia; Infant; Liver; Liver Diseases; Male; Metabolic Diseases; Methionine; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Young Adult | 2016 |
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Homocysteine; Humans; Methionine; Neoplasms; RNA; S-Adenosylmethionine; Serine; Stress, Physiological | 2016 |
Metabolic engineering of Corynebacterium glutamicum ATCC13032 to produce S-adenosyl-L-methionine.
Topics: Bacterial Proteins; Biosynthetic Pathways; Corynebacterium glutamicum; Fermentation; Gene Deletion; Genes, Bacterial; Metabolic Engineering; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 2016 |
Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat.
Topics: Aging; Animals; Cystathionine beta-Synthase; Diet; Hydrogen Sulfide; Liver; Longevity; Methionine; Mole Rats; Rats; S-Adenosylmethionine | 2016 |
Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans.
Topics: Adipose Tissue; Adult; Blood Glucose; Body Mass Index; Cholesterol, LDL; Cross-Sectional Studies; Dietary Fats; Dietary Proteins; Energy Intake; Female; Humans; Insulin; Male; Methionine; Overnutrition; S-Adenosylmethionine; Weight Gain | 2016 |
Effects of Nonpurified and Choline Supplemented or Nonsupplemented Purified Diets on Hepatic Steatosis and Methionine Metabolism in C3H Mice.
Topics: Animals; Choline; Diet; Dietary Fats; Dietary Sucrose; Dietary Supplements; Fatty Liver; Feeding Behavior; Female; Lipid Metabolism; Liver; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine | 2016 |
One-pot modification of 5'-capped RNA based on methionine analogs.
Topics: Binding Sites; Click Chemistry; Methionine; Methyltransferases; RNA, Messenger; S-Adenosylmethionine | 2016 |
Improving methionine and ATP availability by MET6 and SAM2 co-expression combined with sodium citrate feeding enhanced SAM accumulation in Saccharomyces cerevisiae.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosine Triphosphate; Bioreactors; Citrates; Culture Media; Feasibility Studies; Fermentation; Isocitrate Dehydrogenase; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sodium Citrate | 2016 |
S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Topics: Crystallography, X-Ray; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methionine; Mutation; Peptide Fragments; S-Adenosylmethionine; Substrate Specificity | 2016 |
Chemoenzymatic synthesis and utilization of a SAM analog with an isomorphic nucleobase.
Topics: Adenosine; Biocatalysis; Methionine; Methyltransferases; Molecular Structure; S-Adenosylmethionine | 2016 |
MTHFD1 controls DNA methylation in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Cytoplasm; DNA Demethylation; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Expression Regulation, Plant; Gene Silencing; Green Fluorescent Proteins; Histones; Homeostasis; Lysine; Methenyltetrahydrofolate Cyclohydrolase; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Models, Biological; Mutation; Protein Transport; S-Adenosylmethionine; Tetrahydrofolates | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
The effect of increasing concentrations of dl-methionine and 2-hydroxy-4-(methylthio) butanoic acid on hepatic genes controlling methionine regeneration and gluconeogenesis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Animals, Newborn; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine O-Palmitoyltransferase; Cattle; Down-Regulation; Gluconeogenesis; Glucose-6-Phosphatase; Hepatocytes; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methylenetetrahydrofolate Reductase (NADPH2); Phosphoenolpyruvate Carboxykinase (GTP); S-Adenosylmethionine; Up-Regulation | 2016 |
S-Adenosylmethionine Synthetase 3 Is Important for Pollen Tube Growth.
Topics: Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Histones; Metabolomics; Methionine; Methionine Adenosyltransferase; Methylation; Microscopy, Fluorescence; Mutation; Plants, Genetically Modified; Pollen; Pollen Tube; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Seeds | 2016 |
Methionine Metabolites in Patients With Sepsis.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Catheter-Related Infections; Cohort Studies; Female; Homocysteine; Hospital Mortality; Humans; Intraabdominal Infections; Logistic Models; Male; Methionine; Middle Aged; Prognosis; Prospective Studies; Respiratory Tract Infections; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis; Skin Diseases, Infectious; Urinary Tract Infections | 2018 |
Stimulating S-adenosyl-l-methionine synthesis extends lifespan via activation of AMPK.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Caloric Restriction; Epistasis, Genetic; Genes, Dominant; Glucan 1,3-beta-Glucosidase; Longevity; Metabolic Networks and Pathways; Methionine; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae | 2016 |
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism.
Topics: Adenosine Triphosphate; Amino Acid Transport Systems; Apoptosis; Calcium-Binding Proteins; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cytochromes c; DNA Methylation; DNA, Mitochondrial; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Methionine; Mitochondria; Promoter Regions, Genetic; S-Adenosylmethionine; Uterine Cervical Neoplasms | 2017 |
De novo biosynthesis of pterostilbene in an Escherichia coli strain using a new resveratrol O-methyltransferase from Arabidopsis.
Topics: Acyltransferases; Ammonia-Lyases; Arabidopsis; Biocatalysis; Escherichia coli; Metabolic Engineering; Metabolic Networks and Pathways; Methionine; Methyltransferases; Resveratrol; S-Adenosylmethionine; Stilbenes; Tyrosine | 2017 |
Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Extracellular Vesicles; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Methionine; Neoplasms; S-Adenosylmethionine | 2017 |
Spermidine promotes
Topics: Adenosylmethionine Decarboxylase; Bacillus subtilis; Bacterial Proteins; Biofilms; Cadaverine; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Methionine; Methylation; Nitrogen Cycle; Operon; Polysaccharides, Bacterial; Purines; S-Adenosylmethionine; Single-Cell Analysis; Spermidine; Transcription Factors | 2017 |
Catalysis by solvation rather than the desolvation effect: exploring the catalytic efficiency of SAM-dependent chlorinase.
Topics: Biocatalysis; Catalytic Domain; Cladribine; Hydrogen Bonding; Methionine; Methyltransferases; Mutagenesis, Site-Directed; S-Adenosylmethionine; Static Electricity; Thermodynamics; Water | 2017 |
Biosynthesis of S-Adenosylmethionine by Magnetically Immobilized Escherichia coli Cells Highly Expressing a Methionine Adenosyltransferase Variant.
Topics: Adenosine Triphosphate; Bioreactors; Escherichia coli; Methionine; Methionine Adenosyltransferase; Nanoparticles; S-Adenosylmethionine | 2017 |
Leucine responsive regulatory protein is involved in methionine metabolism and polyamine homeostasis in acetic acid bacterium Komagataeibacter europaeus.
Topics: Acetic Acid; Gene Deletion; Gluconacetobacter; Homeostasis; Leucine-Responsive Regulatory Protein; Methionine; Methionine Adenosyltransferase; Polyamines; S-Adenosylmethionine; Spermidine | 2018 |
[Purification and characterization of S-adenosyl-L-methionine:uroporphyrinogen Ⅲ methyltransferase from Rhodobacter capsulatus SB1003].
Topics: Escherichia coli; Methionine; Methyltransferases; Pseudomonas; Rhodobacter capsulatus; S-Adenosylmethionine; Uroporphyrinogens; Uroporphyrins | 2017 |
Complementation of a metK-deficient E. coli strain with heterologous AdoMet synthetase genes.
Topics: Bacteria; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Fungal Proteins; Fungi; Genetic Complementation Test; Humans; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 2017 |
Topics: Antioxidants; Glutathione; Hepacivirus; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 2017 |
Differential metabolism of L-phenylalanine in the formation of aromatic volatiles in melon (Cucumis melo L.) fruit.
Topics: Cucumis melo; Fruit; Glucosides; Glycosylation; Methionine; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Proteins; S-Adenosylmethionine; Seeds; Volatile Organic Compounds | 2018 |
Nutritional Control of Stem Cell Division through S-Adenosylmethionine in Drosophila Intestine.
Topics: Animals; Cell Differentiation; Cell Self Renewal; Drosophila melanogaster; Drosophila Proteins; Enterocytes; Female; Homeostasis; Interleukin-6; Intestinal Mucosa; Intestines; Male; Methionine; Nutritional Status; S-Adenosylmethionine; Stem Cells | 2018 |
Preparation, Assay, and Application of Chlorinase SalL for the Chemoenzymatic Synthesis of S-Adenosyl-l-Methionine and Analogs.
Topics: Bacterial Proteins; Biochemistry; Catalysis; Cladribine; Enzymes; Methionine; Micromonosporaceae; Recombinant Proteins; S-Adenosylmethionine | 2018 |
Promiscuity of methionine salvage pathway enzymes in Methanocaldococcus jannaschii.
Topics: Bacterial Proteins; Biosynthetic Pathways; Deoxyadenosines; Fructosephosphates; Gene Expression; Genetic Complementation Test; Kinetics; Methanocaldococcus; Methanosarcina; Methionine; Molecular Weight; Recombinant Proteins; S-Adenosylmethionine; Species Specificity; Substrate Specificity | 2018 |
The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Enzyme Activation; Homocysteine; Homocystinuria; Methionine; Mice; Mole Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2018 |
Neonatal methionine adenosyltransferase I/III deficiency with abnormal signal intensity in the central tegmental tract.
Topics: Amino Acid Metabolism, Inborn Errors; Brain; Demyelinating Diseases; Glycine N-Methyltransferase; Humans; Infant; Infant, Newborn; Male; Methionine; Methionine Adenosyltransferase; Neonatal Screening; Nervous System Diseases; Pontine Tegmentum; S-Adenosylmethionine | 2019 |
Short communication: The effect of increasing concentrations of different methionine forms and 2-hydroxy-4-(methylthio)butanoic acid on genes controlling methionine metabolism in primary bovine neonatal hepatocytes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Animals, Newborn; Betaine; Betaine-Homocysteine S-Methyltransferase; Butyric Acid; Cattle; Cells, Cultured; Female; Glycine N-Methyltransferase; Hepatocytes; Liver; Methionine; S-Adenosylmethionine | 2019 |
Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation.
Topics: Carbon; Endosomes; Glycogen Synthase Kinase 3 beta; HEK293 Cells; HeLa Cells; Humans; Lysosomes; Methionine; Methotrexate; Methylation; Niacinamide; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Wnt Signaling Pathway | 2019 |
Altered Methionine Metabolism in Cancer Cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Homocysteine; Humans; Methionine; Methylation; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 2019 |
Is the Hoffman Effect for Methionine Overuse Analogous to the Warburg Effect for Glucose Overuse in Cancer?
Topics: Aneuploidy; DNA Methylation; G2 Phase; Genomic Instability; Glucose; Glycolysis; Humans; Methionine; Neoplasms; S Phase; S-Adenosylmethionine | 2019 |
Methionine is a metabolic dependency of tumor-initiating cells.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Cell Line, Tumor; Female; Gene Knockdown Techniques; Glycine Dehydrogenase (Decarboxylating); Humans; Lung Neoplasms; Male; Metabolic Networks and Pathways; Metabolomics; Methionine; Methionine Adenosyltransferase; Mice; Neoplastic Stem Cells; S-Adenosylmethionine | 2019 |
An enzymatic Finkelstein reaction: fluorinase catalyses direct halogen exchange.
Topics: Bacterial Proteins; Catalysis; Deoxyadenosines; Halogens; Kinetics; Methionine; Molecular Conformation; Oxidoreductases; S-Adenosylmethionine; Streptomyces; Thermodynamics | 2019 |
Efficient production of S-adenosyl-l-methionine from dl-methionine in metabolic engineered Saccharomyces cerevisiae.
Topics: Bioreactors; Metabolic Engineering; Methionine; Microorganisms, Genetically-Modified; S-Adenosylmethionine; Saccharomyces cerevisiae | 2019 |
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
Topics: A549 Cells; Animals; Cell Proliferation; Cysteine; Extracellular Space; Female; Gene Knockout Techniques; Hep G2 Cells; Heterografts; Humans; Male; MCF-7 Cells; Methionine; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Protamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tumor Burden | 2019 |
Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia.
Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia; Leukemia, Biphenotypic, Acute; Methionine; Methyltransferases; Oncogene Proteins, Fusion; Protein Processing, Post-Translational; S-Adenosylmethionine | 2019 |
Cyanide produced with ethylene by ACS and its incomplete detoxification by β-CAS in mango inflorescence leads to malformation.
Topics: Amino Acid Oxidoreductases; Cyanides; Ethylenes; Fusarium; Gene Expression Regulation, Plant; Inactivation, Metabolic; Inflorescence; Lyases; Mangifera; Methionine; Phosphates; Plant Diseases; S-Adenosylmethionine | 2019 |
Improved S-adenosyl-l-methionine production in Saccharomyces cerevisiae using tofu yellow serofluid.
Topics: Batch Cell Culture Techniques; Bioreactors; Citric Acid; Culture Media; Ethanol; Fermentation; Methionine; Quaternary Ammonium Compounds; S-Adenosylmethionine; Saccharomyces cerevisiae; Soy Foods | 2020 |
A bifunctional salvage pathway for two distinct S-adenosylmethionine by-products that is widespread in bacteria, including pathogenic Escherichia coli.
Topics: Bacterial Proteins; Carbon; Deoxyadenosines; Dihydroxyacetone Phosphate; Escherichia coli; Fructose-Bisphosphate Aldolase; Isomerases; Metabolic Networks and Pathways; Methionine; N-Glycosyl Hydrolases; Oxygen; Phosphorylases; Phosphotransferases; Rhodospirillum rubrum; S-Adenosylmethionine; Thionucleosides | 2020 |
Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence.
Topics: Animals; Cell Nucleus; Chromatin; Cytoplasm; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; HCT116 Cells; Heterochromatin; Histone-Lysine N-Methyltransferase; Histones; Humans; Metabolome; Methionine; Mice; Protein Processing, Post-Translational; Proteomics; S-Adenosylmethionine | 2020 |
Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis.
Topics: Alkylation; Anti-Bacterial Agents; Biochemical Phenomena; Methionine; Nucleosides; Phosphates; Phosphorylation; Pyridoxal Phosphate; Recombinant Proteins; S-Adenosylmethionine | 2020 |
Genetic variants in S-adenosyl-methionine synthesis pathway and nonsyndromic cleft lip with or without cleft palate in Chile.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Alleles; Chile; Cleft Lip; Cleft Palate; Female; Ferredoxin-NADP Reductase; Gene Frequency; Genes, Dominant; Genes, Recessive; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Male; Methionine; Methionine Adenosyltransferase; Odds Ratio; Polymorphism, Single Nucleotide; S-Adenosylmethionine | 2021 |
Developmental changes in physiological amino acids and hepatic methionine remethylation enzyme activities in E10-21 chick embryos and D1-49 broilers.
Topics: Amino Acids; Animals; Chick Embryo; Chickens; Liver; Methionine; S-Adenosylmethionine | 2020 |
A Tug-of-War Over Methionine.
Topics: Histones; Methionine; Methylation; Neoplasms; S-Adenosylmethionine; T-Lymphocytes | 2020 |
Ontogeny of hepatic methionine catabolic enzyme activities (Transmethylation and Transsulphuration) and associated physiological amino acids in E10-21 chick embryos and D1-49 broilers.
Topics: Amino Acids; Animals; Chick Embryo; Chickens; Growth and Development; Liver; Methionine; S-Adenosylmethionine | 2021 |
Here, There, and Everywhere: Plastid- and Nuclear-Localized WHIRLY1 Regulates Salicylic Acid Homeostasis during Developmental Senescence.
Topics: Ammonia; Chorismic Acid; Homeostasis; Methionine; Phenylalanine; Plastids; S-Adenosylmethionine; Salicylic Acid | 2020 |
Reduction of fatty liver in rats by nicotinamide via the regeneration of the methionine cycle and the inhibition of aldehyde oxidase.
Topics: Administration, Oral; Aldehyde Oxidase; Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Hydralazine; Lipid Droplets; Liver; Male; Methionine; Niacinamide; Non-alcoholic Fatty Liver Disease; Rats, Sprague-Dawley; S-Adenosylmethionine; Triglycerides | 2021 |
MetW regulates the enzymatic activity of MetX in Pseudomonas.
Topics: Acetyltransferases; Amino Acid Sequence; Binding Sites; Methionine; Pseudomonas aeruginosa; S-Adenosylmethionine | 2021 |
Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
Topics: Animals; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cell Line, Tumor; CRISPR-Cas Systems; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Liver; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylmethionine; T-Lymphocytes; Transcriptome | 2021 |
Identification of novel metabolic engineering targets for S-adenosyl-L-methionine production in Saccharomyces cerevisiae via genome-scale engineering.
Topics: Metabolic Engineering; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae | 2021 |
STK11/LKB1 Loss of Function Is Associated with Global DNA Hypomethylation and
Topics: Adenocarcinoma; AMP-Activated Protein Kinase Kinases; Cell Line; Cell Survival; Cluster Analysis; Computational Biology; CpG Islands; Databases, Genetic; DNA Methylation; Epigenesis, Genetic; Genes, ras; Humans; Lung Neoplasms; Methionine; Mutation; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins p21(ras); Repetitive Sequences, Nucleic Acid; S-Adenosylmethionine | 2021 |
Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level.
Topics: Aging; Animals; Betaine; Gene Expression Regulation; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Lysosomes; Male; Mechanistic Target of Rapamycin Complex 1; Methionine; Methyltransferases; Mice, Inbred C57BL; Muscle, Skeletal; Protein Biosynthesis; S-Adenosylmethionine; Signal Transduction | 2021 |
Profiling and Validation of Live-Cell Protein Methylation with Engineered Enzymes and Methionine Analogues.
Topics: Humans; Methionine; Methylation; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Proteome; Repressor Proteins; S-Adenosylmethionine | 2021 |
Insights into the mutations leading to capreomycin resistance in S-adenosyl-L-methionine binding motif in TlyA from
Topics: Bacterial Proteins; Capreomycin; Methionine; Methyltransferases; Mutation; Mycobacterium tuberculosis; S-Adenosylmethionine | 2022 |
Identification of methionine adenosyltransferase with high diastereoselectivity for biocatalytic synthesis of (S)-S-adenosyl-l-methionine and exploring its relationship with fluorinated biosynthetic pathway.
Topics: Biosynthetic Pathways; Methionine; Methionine Adenosyltransferase; Molecular Docking Simulation; S-Adenosylmethionine; Streptomyces | 2021 |
Chemoenzymatic labeling of RNA to enrich, detect and identify methyltransferase-target sites.
Topics: Adenosine; Methionine; Methyltransferases; RNA; S-Adenosylmethionine | 2021 |
Implications of divergence of methionine adenosyltransferase in archaea.
Topics: Archaea; Catalytic Domain; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 2022 |
Human Mat2A Uses an Ordered Kinetic Mechanism and Is Stabilized but Not Regulated by Mat2B.
Topics: Adenosine Triphosphate; Enzyme Stability; Humans; Kinetics; Methionine; Methionine Adenosyltransferase; Recombinant Proteins; S-Adenosylmethionine | 2021 |
Maternal and neonatal one-carbon metabolites and the epigenome-wide infant response.
Topics: Adult; Betaine; Carbon; Choline; Cohort Studies; DNA Methylation; Epigenome; Female; Fetal Blood; Histone Code; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Metabolomics; Methionine; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine | 2022 |
Oligomerization engineering of the fluorinase enzyme leads to an active trimer that supports synthesis of fluorometabolites in vitro.
Topics: Bacterial Proteins; Methionine; Oxidoreductases; S-Adenosylmethionine; Streptomyces | 2022 |
Broken-Symmetry Density Functional Theory Analysis of the Ω Intermediate in Radical
Topics: Density Functional Theory; Iron-Sulfur Proteins; Methionine; S-Adenosylmethionine; Sulfur | 2022 |
Topics: Catalysis; Electron Spin Resonance Spectroscopy; Free Radicals; Methionine; S-Adenosylmethionine | 2022 |
The Atypical Cobalamin-Dependent
Topics: Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Methyl Metabolism and the Clock: An Ancient Story With New Perspectives.
Topics: Animals; Circadian Rhythm; Folic Acid; Humans; Mammals; Methionine; Methylation; S-Adenosylmethionine | 2022 |
Down-regulation of PvSAMS impairs S-adenosyl-L-methionine and lignin biosynthesis, and improves cell wall digestibility in switchgrass.
Topics: Cell Wall; Down-Regulation; Gene Expression Regulation, Plant; Lignin; Methionine; Panicum; Plants, Genetically Modified; S-Adenosylmethionine; Sulfur | 2022 |
Chemo-Enzymatic Modification of the 5' Cap To Study mRNAs.
Topics: COVID-19 Vaccines; Humans; Methionine; Methyltransferases; Nucleotides; RNA; RNA, Messenger; S-Adenosylmethionine | 2022 |
Glycogen Storage Disease Phenotypes Accompanying the Perturbation of the Methionine Cycle in NDRG3-Deficient Mouse Livers.
Topics: Animals; Glucose; Glycogen Storage Disease; Liver; Methionine; Mice; Mice, Knockout; Phenotype; S-Adenosylmethionine | 2022 |
Methionine Deprivation Reveals the Pivotal Roles of Cell Cycle Progression in Ferroptosis That Is Induced by Cysteine Starvation.
Topics: Cell Cycle; Cysteine; Cystine; Ferroptosis; Glutathione; HeLa Cells; Humans; Methionine; Reactive Oxygen Species; S-Adenosylmethionine | 2022 |
mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine.
Topics: Animals; Humans; Mammals; Mechanistic Target of Rapamycin Complex 1; Methionine; Methionine Adenosyltransferase; Methylation; RNA, Messenger; S-Adenosylmethionine | 2022 |
PhoP- and GlnR-mediated regulation of metK transcription and its impact upon S-adenosyl-methionine biosynthesis in Saccharopolyspora erythraea.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Erythromycin; Gene Expression Regulation, Bacterial; Methionine; Nitrogen; Phosphates; S-Adenosylmethionine; Saccharopolyspora | 2022 |
Characterization of SET-Domain Histone Lysine Methyltransferase Substrates Using a Cofactor S-Adenosyl-L-Methionine Surrogate.
Topics: Histone-Lysine N-Methyltransferase; Methionine; PR-SET Domains; Proteomics; S-Adenosylmethionine | 2022 |
Topics: Animals; Cryoelectron Microscopy; Cystathionine beta-Synthase; Cysteine; Methionine; Mice; Mycobacterium tuberculosis; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylmethionine; Sulfur | 2022 |
Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization.
Topics: Cell Differentiation; Methionine; Pluripotent Stem Cells; S-Adenosylmethionine; Signal Transduction; Zinc | 2022 |
Association of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community.
Topics: Dementia; Humans; Methionine; Proportional Hazards Models; S-Adenosylhomocysteine; S-Adenosylmethionine | 2022 |
Dietary methionine starvation impairs acute myeloid leukemia progression.
Topics: Animals; Histones; Leukemia, Myeloid, Acute; Methionine; Mice; Racemethionine; S-Adenosylmethionine | 2022 |
S-Adenosyl-L-Methionine and Cu(II) Impact Green Plant Regeneration Efficiency.
Topics: Amplified Fragment Length Polymorphism Analysis; Methionine; Methylation; S-Adenosylmethionine; Triticale | 2022 |
DNA methylation of angiogenic gene in the gastric cancer and fate of S-adenosyl-l-methionine, the donor of the methyl group.
Topics: DNA Methylation; Humans; Methionine; Racemethionine; S-Adenosylmethionine; Stomach Neoplasms | 2023 |
Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Caenorhabditis elegans; Carbon; Dithiothreitol; Folic Acid; Homocysteine; Hydrogen Sulfide; Ligases; Lipids; Mercaptoethanol; Methionine; Methyltransferases; Nucleic Acids; Oxygen; Reducing Agents; S-Adenosylmethionine; Sulfhydryl Compounds; Vitamin B 12; Vitamins | 2022 |
Enzymatic Generation of Double-Modified AdoMet Analogues and Their Application in Cascade Reactions with Different Methyltransferases.
Topics: Adenosine Triphosphate; Alkylation; Methionine; Methyltransferases; Racemethionine; S-Adenosylmethionine | 2022 |
Insertion of 4-Demethylwyosine in tRNA
Topics: Carbon Dioxide; Catalysis; Iron-Sulfur Proteins; Methionine; Oxidative Stress; Oxidoreductases; Pyruvic Acid; RNA, Transfer; RNA, Transfer, Phe; S-Adenosylmethionine | 2022 |
Mechanism of
Topics: Methionine; Methylation; Methyltransferases; Racemethionine; S-Adenosylmethionine; Vitamin B 12 | 2022 |
Transient Methionine Deprivation Triggers Histone Modification and Potentiates Differentiation of Induced Pluripotent Stem Cells.
Topics: Cell Differentiation; Embryonic Stem Cells; Epigenesis, Genetic; Histone Code; Humans; Induced Pluripotent Stem Cells; Methionine; Racemethionine; S-Adenosylmethionine | 2023 |
One-carbon metabolite supplementation to heifers for the first 14 d of the estrous cycle alters the plasma and hepatic one-carbon metabolite pool and methionine-folate cycle enzyme transcript abundance in a dose-dependent manner.
Topics: Animals; Carbon; Cattle; Choline; Dietary Supplements; Estrous Cycle; Female; Folic Acid; Liver; Methionine; Racemethionine; Rumen; S-Adenosylmethionine | 2023 |
Improving ATP availability by sod1 deletion with a strategy of precursor feeding enhanced S-adenosyl-L-methionine accumulation in Saccharomyces cerevisiae.
Topics: Adenosine Triphosphate; Fermentation; Methionine; S-Adenosylmethionine; Saccharomyces cerevisiae; Superoxide Dismutase-1 | 2023 |
Anammox Bacterial
Topics: Acyl Carrier Protein; Anaerobic Ammonia Oxidation; Bacteria; Bacterial Proteins; Lipids; Methionine; Methyltransferases; Racemethionine; S-Adenosylmethionine | 2023 |
High-Throughput Screening and Directed Evolution of Methionine Adenosyltransferase from Escherichia coli.
Topics: Escherichia coli; High-Throughput Screening Assays; Methionine; Methionine Adenosyltransferase; Racemethionine; S-Adenosylmethionine | 2023 |
Revisiting One-Carbon Metabolites in Human Breast Milk: Focus on S-Adenosylmethionine.
Topics: Adult; Carbon; Child; Chromatography, Liquid; Female; Homocysteine; Humans; Infant; Methionine; Milk, Human; Racemethionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2023 |
Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups.
Topics: Animals; Choline; Glycerylphosphorylcholine; Liver; Lysophospholipase; Methionine; Mice; Phosphatidylcholines; Racemethionine; S-Adenosylmethionine; Triglycerides | 2023 |
Lack of Association of
Topics: Breast Neoplasms; Female; Homocysteine; Humans; Mali; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); S-Adenosylmethionine | 2023 |
Optimization of Hydrogenobyrinic Acid Synthesis in a Cell-Free Multienzyme Reaction by Novel
Topics: Cell-Free System; Homocysteine; Methionine; Methyltransferases; S-Adenosylmethionine | 2023 |
S-adenosyl-L-methionine supplementation alleviates damaged intestinal epithelium and inflammatory infiltration caused by Mat2a deficiency.
Topics: Animals; Dietary Supplements; Intestinal Mucosa; Methionine; Methionine Adenosyltransferase; Mice; S-Adenosylmethionine | 2023 |
Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage.
Topics: Acetyltransferases; Catalytic Domain; Crystallization; Dithionite; Electron Spin Resonance Spectroscopy; Iron-Sulfur Proteins; Methionine; Oxidation-Reduction; S-Adenosylmethionine | 2023 |
Enzymatic Synthesis of l-Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade.
Topics: Alkylation; Catalysis; Homocysteine; Homoserine; Methionine; Methyltransferases; S-Adenosylmethionine | 2023 |
Methionine-producing tumor micro(be) environment fuels growth of solid tumors.
Topics: Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Proliferation; Escherichia coli; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mammals; Methionine; Racemethionine; S-Adenosylmethionine; Tumor Microenvironment | 2023 |
Synthesis of S-Adenosyl-L-Methionine Analogs with Extended Transferable Groups for Methyltransferase-Directed Labeling of DNA and RNA.
Topics: DNA; Methionine; Methyltransferases; Racemethionine; RNA; S-Adenosylmethionine | 2023 |
Biocatalytic Fluoroalkylation Using Fluorinated
Topics: Biocatalysis; Humans; Methionine; Methyltransferases; Racemethionine; S-Adenosylmethionine | 2023 |
Nucleoside-Driven Specificity of DNA Methyltransferase.
Topics: Adenosine; DNA; DNA Methylation; Methionine; Methyltransferases; Nucleosides; S-Adenosylmethionine | 2023 |
Genome-scale metabolic model analysis of Pichia pastoris for enhancing the production of S-adenosyl-L-methionine.
Topics: Carbon; Methionine; Racemethionine; S-Adenosylmethionine | 2023 |
Plasma One-Carbon Metabolism-Related Micronutrients and the Risk of Breast Cancer: Involvement of DNA Methylation.
Topics: Breast Neoplasms; Carbon; Case-Control Studies; Choline; Cysteine; DNA Methylation; Female; Folic Acid; Humans; Methionine; Micronutrients; Racemethionine; S-Adenosylmethionine; Trace Elements | 2023 |
Production of S-methyl-methionine using engineered Saccharomyces cerevisiae sake K6.
Topics: Methionine; Methyltransferases; Racemethionine; S-Adenosylmethionine; Saccharomyces cerevisiae; Vitamin U | 2023 |
METTL16 controls Kaposi's sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle.
Topics: Cystathionine; Herpesvirus 8, Human; Methionine; RNA; S-Adenosylmethionine | 2023 |
The importance of preconception Hcy testing: identification of a folate trap syndrome in a woman attending an assisted reproduction program.
Topics: Female; Folic Acid; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Reproduction; S-Adenosylmethionine | 2023 |
Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Folic Acid; Methionine; S-Adenosylmethionine; Vitamin B 12 | 2023 |
Structural and Biochemical Studies on Product Inhibition of S-Adenosylmethionine Synthetase from
Topics: Adenosine Triphosphate; Corynebacterium glutamicum; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 2023 |
Methionine-CBS axis promotes intracellular ROS levels by reprogramming serine metabolism.
Topics: Cysteine; Methionine; Racemethionine; Reactive Oxygen Species; S-Adenosylmethionine; Serine | 2023 |
Pyruvate formate-lyase activating enzyme: The catalytically active 5'-deoxyadenosyl radical caught in the act of H-atom abstraction.
Topics: Acetyltransferases; Electron Spin Resonance Spectroscopy; Iron-Sulfur Proteins; Methionine; Peptides; S-Adenosylmethionine | 2023 |