methionine has been researched along with s-adenosylhomocysteine in 175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (28.57) | 18.7374 |
| 1990's | 23 (13.14) | 18.2507 |
| 2000's | 54 (30.86) | 29.6817 |
| 2010's | 43 (24.57) | 24.3611 |
| 2020's | 5 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Bréard, M; Courtois, F; Drujon, T; Guérard, C; Ploux, O | 1 |
| Butt, VS; Poulton, JE | 1 |
| Cook, DE; Dang, AQ | 1 |
| Lawrence, F; Lederer, E; Legraverend, M; Robert-Géro, M; Vedel, M | 1 |
| Eloranta, TO | 1 |
| Eloranta, TO; Raina, AM | 1 |
| Shugart, L | 1 |
| Altman, NH; Brada, Z; Bulba, S | 1 |
| Schatz, RA; Sellinger, OZ | 1 |
| Finkelstein, JD; Harris, B | 1 |
| Ballinger, MD; Eliasson, R; Harder, J; Pontis, E; Reichard, P | 1 |
| Poirier, LA; Wainfan, E | 1 |
| Fullerton, FR; Hathcock, JN; Poirier, LA; Reicks, MM; Whittaker, P | 1 |
| Fell, D; Selhub, J | 1 |
| Cumaraswamy, A; Henney, H | 1 |
| Bottiglieri, T; Chanarin, I; Metz, J; Van der Westhuyzen, J; Vieira-Makings, E | 1 |
| Ellis, M; Frost, P; Judde, JG | 1 |
| Henning, SM; McKee, RW; Swendseid, ME | 1 |
| LeBel, CP; Schatz, RA | 1 |
| Cook, RJ; Horne, DW; Wagner, C | 1 |
| Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Horne, DW | 1 |
| Dyer, JR; Greenwood, CE | 1 |
| Finkelstein, JD; Martin, JJ | 2 |
| Djurhuus, R; Lillehaug, JR; Male, R; Svardal, AM; Ueland, PM | 1 |
| Hariyama, H; Moriguchi, K; Sato, H | 1 |
| Creasia, D; Hoover, KL; Mikol, YB; Poirier, LA; Shivapurkar, N; Wilson, MJ | 1 |
| Stipanuk, MH | 1 |
| Matos, JR; Raushel, FM; Wong, CH | 1 |
| Duerre, JA; Wallwork, JC | 2 |
| Carrera, CJ; Carson, DA; Kajander, EO; Kubota, M; Montgomery, JA | 1 |
| Djurhuus, R; Refsum, H; Svardal, AM; Ueland, PM | 1 |
| Glazer, RI; Haines, DR; Knode, MC; Marquez, VE; Tseng, CK | 1 |
| Fall, R; Murphy, SE | 1 |
| Snoswell, AM; Xue, GP | 1 |
| Dev, VG; Mixon, JC | 1 |
| Hoffman, RM | 1 |
| Cornatzer, WE; Haning, JA; Hoffman, DR | 1 |
| Coalson, DW; Hoffman, RM; Mecham, JO; Stern, PH | 1 |
| Hoffman, RM; Mecham, JO; Stern, PH; Wallace, CD | 1 |
| Hoffman, RM; Stern, PH | 1 |
| Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
| Barber, JR; Clarke, S | 1 |
| Hoffman, RM; Stern, PH; Wallace, CD | 1 |
| Borchardt, RT; Keller, BT | 1 |
| Poirier, LA; Shivapurkar, N; Wilson, MJ | 1 |
| DiMaria, P; Kim, S; Ro, JY | 1 |
| Clarke, S; Oden, KL | 1 |
| Poirier, LA; Shivapurkar, N | 1 |
| Borchardt, RT; Eiden, LE; Rutledge, CO | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, WE; Martin, JJ | 1 |
| Doyle, RL; Porta, R; Schatz, RA; Sellinger, OZ; Tatter, SB; Wilens, TE | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR; Marion, DW | 1 |
| Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G | 1 |
| Blom, HJ; Copius Peereboom-Stegeman, JH; Deabreu, RA; Eskes, TK; Noordhoek, J; Trijbels, FJ; Vanaerts, LA | 1 |
| Linder, M; Scholtissek, C; Woyciniuk, P | 1 |
| Phillips, K; Phillips, SE | 1 |
| Adams, RL; Macnab, JC; Seivwright, C | 1 |
| Fullerton, FR; Hansen, DK; Knowles, BJ; Poirier, LA | 1 |
| Blaydes, BS; Fullerton, FR; Greenman, DL; Poirier, LA | 1 |
| Alleman, MM; Bacchi, CJ; Dwyer, DM; Gottlieb, M; Mann, VH; Yarlett, N | 1 |
| Schalinske, KL; Steele, RD | 1 |
| Allen, RH; Chandler, CJ; Halsted, CH; James, SJ; Muskhelishvili, L; Poirier, L; Stabler, SP; Villanueva, J | 1 |
| Blom, HJ; Bökkerink, JP; De Abreu, RA; Keuzenkamp-Jansen, CW; Trijbels, JM | 1 |
| Angst, CP; Browne, G; Fowler, B; Frick, G; Haefeli, WE; Loehrer, FM | 1 |
| Cheng, X; Klimasauskas, S; O'Gara, M; Roberts, RJ | 1 |
| Holloway, RS; Horne, DW; Wagner, C | 1 |
| Angst, CP; Fowler, B; Haefeli, WE; Loehrer, FM; Schwab, R | 1 |
| Brunone, M; De Santo, NG; Galletti, P; Ingrosso, D; Perna, AF; Zappia, V | 1 |
| Capdevila, A; Wagner, C | 1 |
| Finkelstein, JD | 1 |
| Bacchi, CJ; Goldberg, B; Lloyd, D; Rattendi, D; Sufrin, JR | 1 |
| Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P | 1 |
| Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD | 1 |
| Ge, R; Kramer, PM; Pereira, MA; Tao, L; Wang, W; Yang, S | 1 |
| Rowling, MJ; Schalinske, KL | 1 |
| Kramer, PM; Pereira, MA; Tao, L; Wang, W; Yang, S | 1 |
| Deng, L; Hiou-Tim, F; James, SJ; Melnyk, S; Pogribny, IP; Rozen, R; Sibani, S; Trasler, J; Wang, W | 1 |
| Charlton, CG; Darling-Reed, S; Lamango, N; Lee, ES; Reuben, JS; Shepherd, KR; Soliman, KF; Williams, Z; Zhao, WQ | 1 |
| Chipman, DC; McMullen, MH; Rowling, MJ; Schalinske, KL | 1 |
| Alonso-Aperte, E; Ubeda, N; Varela-Moreiras, G | 1 |
| Junker, E; Lauterburg, BH; Russmann, S | 1 |
| Driskell, LO; Tucker, AM; Winkler, HH; Wood, DO | 1 |
| Choi, KH; Kim, SK; Kim, YC | 1 |
| Brown-Borg, HM; Uthus, EO | 1 |
| Bujnicki, JM; Chiang, PK; Ginalski, K; Gordon, RK; Pankaskie, MC; Rudnicki, WR; Rychlewski, L | 1 |
| Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Tuma, DJ | 1 |
| SHAPIRO, SK | 1 |
| Chen, A; Davidson, AG; Dyer, R; Innis, SM; James, SJ; Melnyk, S | 1 |
| Nijhout, HF; Reed, MC; Sparks, R; Ulrich, CM | 1 |
| Ahmad, A; Allen, RH; Panayiotidis, MI; Stabler, SP; White, CW | 1 |
| Hsu, JL; James, SJ; Janke, SM; Jernigan, S; Lane, RH; MacLennan, NK; Melnyk, S; Pham, TD; Piroozi, A | 1 |
| Avila, MA; Corrales, FJ; García-Trevijano, ER; Lu, SC; Mato, JM | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Cleves, MA; Hobbs, CA; James, SJ; Melnyk, S; Zhao, W | 1 |
| Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S | 1 |
| Amanlou, M; Dehghani, M; Dehpour, AR; Ebrahimkhani, MR; Farsam, H; Honar, H; Kiani, S; Mirazi, N; Pasalar, P; Payabvash, S; Riazi, K; Sadeghipour, H | 1 |
| Fowler, B; Herrmann, W; Kuhlmann, MK; Makowski, J; Obeid, R; Schorr, H | 1 |
| Luchowski, P; Stazka, J; Urbanska, EM | 1 |
| Clarke, S; Farrar, CE | 1 |
| Green, RM; Igolnikov, AC | 1 |
| Waterland, RA | 1 |
| Fernstrom, JD; Mudd, SH | 1 |
| Fukada, S; Kawagishi, H; Morita, T; Sekiya, A; Sugiyama, K | 1 |
| Baker, SM; Bock, K; Boris, M; Bradstreet, JJ; Cleves, MA; Cutler, P; Gaylor, DW; Halsted, CH; James, SJ; Jernigan, S; Melnyk, S; Wong, DH | 1 |
| Hayakawa, T; Isa, Y; Tsuge, H | 1 |
| Baggott, JE; Tamura, T | 3 |
| Bottiglieri, T; Cross, JC; Elmore, CL; Gravel, RA; Krupenko, NI; Krupenko, SA; Leclerc, D; Matthews, RG; Rozen, R; Watson, ED; Wu, X | 1 |
| Achón, M; Alonso-Aperte, E; Ubeda, N; Varela-Moreiras, G | 1 |
| Kharbanda, KK | 2 |
| Andria, G; D'Angelo, S; D'Aniello, A; De Bonis, ML; Galletti, P; Ingrosso, D; Raimo, M; Scala, I; Sorrentino, A; Zappia, V | 1 |
| Chen, YJ; Chen, YM; Chiang, EP; Hsiao, M; Huang, SF; Hwang, SF; Lee, YH; Li, AF; Li, YS; Liu, SP; Tsai, TF | 1 |
| Guo, H; Hou, M; Hu, Y; Ling, W; Liu, C; Ma, J; Tang, Z; Wang, Q; Xia, M; Yuan, Q; Zhu, H | 1 |
| Breaker, RR; Lee, ER; Lim, J; Morales, DR; Wang, JX | 1 |
| Chang, CC; Chang, JH; Chien, YW; Huang, SY; Tsen, JH; Yang, HT | 1 |
| Han, T; James, SR; Karpf, AR; Melnyk, S; Pogribny, IP; Tryndyak, VP | 1 |
| Blom, H; Linnebank, M; Moskau, S; Semmler, A; Smith, D; Smulders, Y; Struys, E | 1 |
| Allen, RH; Panayiotidis, MI; Pappa, A; Stabler, SP; White, CW | 1 |
| Chao, WH; Crivello, NA; D'Anci, KE; Rosenberg, IH; Selhub, J; Shukitt-Hale, B; Smith, DE; Troen, AM | 1 |
| Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Tami, A; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M | 1 |
| Kawakami, Y; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Mori, M; Morita, T; Ohuchi, S; Sugiyama, K | 1 |
| Baba, T; Kobayashi, Y; Matsumoto, M; Murai, H; Nishimura, N; Nohara, K; Sano, T; Suzuki, T; Tateishi, Y | 1 |
| Wagner, C | 1 |
| Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC | 1 |
| Amaral, CL; Antunes, LM; Bianchi, Mde L; Bueno, Rde B; Burim, RV; Queiroz, RH | 1 |
| Benight, NM; Burrin, DG; Chacko, S; da Silva, VR; Gregory, JF; Marini, JC; Stabler, SP; Stoll, B | 1 |
| Han, YZ; Ren, ZM; Yu, DN; Zhang, WJ | 1 |
| Balasubramaniam, S; Bjursell, MK; Blom, HJ; Brandberg, G; Cayuela, JA; Engvall, ML; Falkenberg, M; Gustafsson, CM; Halldin, M; Jakobs, C; Lesko, N; Lundeberg, J; Smith, D; Struys, E; von Döbeln, U; Wedell, A | 1 |
| Ling, W; Luo, X; Song, F; Xia, M; Xiao, Y; Yang, Y | 1 |
| Kim, G; Levine, RL; Zhao, H | 1 |
| Alpert, JE; Arning, E; Bottiglieri, T; Fava, M; Mischoulon, D; Papakostas, GI | 1 |
| Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G | 1 |
| Geisel, J; Gortner, L; Hartmuth, K; Herrmann, W; Nijhout, HF; Obeid, R; Reed, MC; Rohrer, TR | 1 |
| Devaraj, S; Engelberg, JA; Halsted, CH; Havel, PJ; Jiang, JX; Kharbanda, KK; Kim, K; LaSalle, JM; Liu, S; Lönnerdal, B; Medici, V; Shibata, NM; Török, NJ; Woods, R | 1 |
| Cronan, JE; Lin, S | 1 |
| Gong, H; Jiang, Y; Shi, Y; Sun, T; Sun, W; Wang, J; Wei, J; Yang, B; Zhang, H | 1 |
| Kang, KW; Kim, SK; Kwak, HC; Lee, JY; Oh, SJ; Phuong, NT; Ryu, CS | 1 |
| Bloom, L; Desiderio, DM; Gardner, LA; Groover, CJ; Hartzes, A; Levin, MC; Yates, CR; Zucker-Levin, AR | 1 |
| Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH | 1 |
| Barto, R; Benoist, JF; Blom, HJ; Czerkiewicz, I; Imbard, A; Muller, F; Rigal, O; Schlemmer, D | 1 |
| Ahumada, V; Arraztoa, JA; Bustos, V; Dobierzewska, A; España-Perrot, PP; Fernández, XB; Figueroa-Diesel, H; Illanes, SE; Pérez-Sepúlveda, A; Rice, GE | 1 |
| D'Angelo, S; Daniele, L; Galletti, P; Monsurrò, MR; Raimo, M; Salvatore, A; Trojsi, F | 1 |
| Adachi, S; Heike, T; Kubota, M; Nakata, R; Shima, M; Takeshita, Y; Watanabe, K | 1 |
| Dekker, JM; Drevon, CA; Elshorbagy, AK; Nijpels, G; Nurk, E; Nygård, O; Refsum, H; Stehouwer, CD; Teerlink, T; Tell, GS; Ueland, PM; Vinknes, KJ; Vollset, SE | 1 |
| Dayal, S; French, SW; Geng, Y; Halsted, CH; Hodzic, E; Kharbanda, KK; LaSalle, JM; Medici, V; Peerson, J; Schroeder, DI; Shibata, NM; Tillman, B; Tsukamoto, H; Woods, R | 1 |
| Doperé, I; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Vansant, G | 1 |
| Geng, Z; Li, X; Shi, N; Wang, S; Wang, Z | 1 |
| Comparotto, H; Deminice, R; Jordao, AA | 1 |
| Kobayashi, Y; Nohara, K; Okamura, K; Sano, T; Takumi, S; Yanagisawa, H | 1 |
| Kim, SK; Kim, YM; Kwak, HC; Oh, SJ | 1 |
| Dolan, SK; Doyle, S; Fitzpatrick, DA; Hammel, S; Jones, GW; Keane, TM; O'Keeffe, G; Owens, RA; Sheridan, KJ; Smith, EB | 1 |
| Ables, G; Bamman, MM; Gómez Padilla, P; Gupta, D; Huang, L; Liu, X; Locasale, JW; Mattocks, D; Mehrmohamadi, M; Mentch, SJ; Nichenametla, SN; Thalacker-Mercer, AE | 1 |
| Ballhausen, D; Blom, HJ; Dionisi-Vici, C; Dobbelaere, D; Douillard, C; Freisinger, P; Grünert, SC; Haas, D; Hoffmann, GF; Kahrizi, K; Kölker, S; la Marca, G; Lindner, M; Makhseed, N; Staufner, C; Straub, BK | 1 |
| Chmiel, KJ; Halsted, CH; Kharbanda, KK; Kim, K; Medici, V; Olson, K; Rutledge, JC; Shibata, NM; Su, RJ; Syed, R; Yokoyama, A | 1 |
| Asara, JM; Binari, R; Demontis, F; Parkhitko, AA; Perrimon, N; Zhang, N | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Apostolakos, MJ; Arning, E; Bottiglieri, T; Doolin, KP; Gough, MS; Mack, CM; Mooney, RA; Morgan, MAM; Pietropaoli, AP; Wexler, O | 1 |
| Augoustides-Savvopoulou, P; Barić, I; Blom, HJ; Chien, YH; Dobbelaere, D; Grünert, SC; Opladen, T; Petković Ramadža, D; Rakić, B; Staufner, C; Wedell, A | 1 |
| Blom, HJ; Castro, R; Esse, R; Koolwijk, P; Tavares de Almeida, I; Teerlink, T | 1 |
| Huse, K; Olecka, M; Platzer, M | 1 |
| Coalson, DW; Douglas Wallace, C; Erbe, RW; Hoffman, RM; Stern, PH | 1 |
| Barroso, M; Castro, R; Esse, R; Tavares de Almeida, I | 1 |
| Berisa, M; Cross, JR; Qin, W; Schwörer, S; Thompson, CB; Zhu, J | 1 |
| Baldi, P; Ceglia, N; Cervantes, M; Forne, I; Fustin, JM; Gaucher, J; Gratton, E; Greco, CM; Imhof, A; Ito, K; Kinouchi, K; Kojima, R; Koronowski, KB; Li, W; Okamura, H; Ranjit, S; Samad, M; Sassone-Corsi, P; Shi, J | 1 |
| Baylin, A; Burant, CF; Dolinoy, DC; Domino, SE; Goodrich, JM; LaBarre, JL; McCabe, CF; Padmanabhan, V; Treadwell, MC | 1 |
| Blackwell, TK; Kanai, M; Kohara, Y; Masumura, K; Mizunuma, M; Ogawa, T; Ohya, Y; Soga, T | 1 |
| Chen, S; Hata, J; Honda, T; Isa, A; Katakura, Y; Kitazono, T; Mihara, A; Nakao, T; Ninomiya, T; Ohara, T; Shimizu, K; Tamrakar, S; Wang, D; Yonemoto, K | 1 |
| Arning, E; Bottiglieri, T; Collado, MC; Demerath, EW; Fields, DA; Isganaitis, E; Lerin, C; Wasek, B | 1 |
11 review(s) available for methionine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Metabolism of sulfur-containing amino acids.
Topics: Adenosylhomocysteinase; Animals; Carboxy-Lyases; Cysteine; Female; Homocysteine; Humans; Hydrolases; Isoenzymes; Liver; Male; Methionine; Methionine Adenosyltransferase; Methylation; Polyamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Taurine; Transaminases | 1986 |
Nitrous oxide, vitamin B12 deficiency and the methyl folate trap.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Humans; Liver; Macaca fascicularis; Methionine; Methylmalonyl-CoA Mutase; Nervous System Diseases; Nitrous Oxide; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12 Deficiency | 1982 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Pathways and regulation of homocysteine metabolism in mammals.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates | 2000 |
Methylthioadenosine.
Topics: Adenine; Animals; Apoptosis; Cell Differentiation; Deoxyadenosines; Gene Expression Regulation; Humans; Methionine; Neoplasms; Purines; S-Adenosylhomocysteine; Thionucleosides | 2004 |
Assessing the effects of high methionine intake on DNA methylation.
Topics: Animals; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Role of transmethylation reactions in alcoholic liver disease.
Topics: Betaine; Humans; Lipotropic Agents; Liver Diseases, Alcoholic; Methionine; Methyltransferases; S-Adenosylhomocysteine | 2007 |
Alcoholic liver disease and methionine metabolism.
Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine; Humans; Liver; Liver Diseases, Alcoholic; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Homocysteine, iron and cardiovascular disease: a hypothesis.
Topics: Biomarkers; Cardiovascular Diseases; Cystathionine; Dietary Supplements; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Lipoproteins, LDL; Methionine; Risk Factors; S-Adenosylhomocysteine; Vitamin B Complex | 2015 |
Consensus recommendations for the diagnosis, treatment and follow-up of inherited methylation disorders.
Topics: Consensus; Homocysteine; Humans; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Methylation; Neonatal Screening; S-Adenosylhomocysteine; S-Adenosylmethionine | 2017 |
The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art.
Topics: Atherosclerosis; Cardiovascular Diseases; Endothelial Cells; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Methionine; Nitric Oxide; Reactive Oxygen Species; S-Adenosylhomocysteine | 2019 |
4 trial(s) available for methionine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Metabolic consequences of folate-induced reduction of hyperhomocysteinemia in uremia.
Topics: Erythrocyte Membrane; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uremia | 1997 |
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation | 2005 |
Iron-dependent formation of homocysteine from methionine and other thioethers.
Topics: Adult; Area Under Curve; Cross-Over Studies; Cystathionine; Female; Homocysteine; Humans; Hydrogen-Ion Concentration; Iron; Iron Chelating Agents; Male; Methionine; S-Adenosylhomocysteine | 2007 |
Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder.
Topics: Biological Availability; Depressive Disorder, Major; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Psychiatric Status Rating Scales; S-Adenosylhomocysteine; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2012 |
160 other study(ies) available for methionine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Synthesis and evaluation of analogues of S-adenosyl-L-methionine, as inhibitors of the E. coli cyclopropane fatty acid synthase.
Topics: Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli Proteins; Methyltransferases; S-Adenosylmethionine | 2004 |
Purification and properties of S-adenosyl-L-homocysteine hydrolase from leaves of spinach beet.
Topics: Adenine; Cysteine; Deoxyadenosines; Homocysteine; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Methionine; Plants; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
The transsulfuration pathway in Tetrahymena pyriformis.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Hydrogen-Ion Concentration; Hydrolases; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Temperature; Tetrahymena pyriformis | 1977 |
Inhibition of tRNA methylation in vitro and in whole cells by an oncostatic S-adenosyl-homocysteine (SAH) analogue: 5'-deoxy 5'-S-isobutyl adenosine (SIBA).
Topics: Avian Sarcoma Viruses; Biological Transport; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cell-Free System; Deoxyadenosines; Dose-Response Relationship, Drug; Methionine; RNA, Transfer; S-Adenosylhomocysteine; Thionucleosides; tRNA Methyltransferases | 1978 |
Tissue distribution of S-adenosylmethionine and S-adenosylhomocysteine in the rat. Effect of age, sex and methionine administration on the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines.
Topics: Age Factors; Animals; Brain; Glycine; Homocysteine; Hydrolases; Kidney; Liver; Methionine; Methionine Adenosyltransferase; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 1977 |
S-adenosylmethionine metabolism and its relation to polyamine synthesis in rat liver. Effect of nutritional state, adrenal function, some drugs and partial hepatectomy.
Topics: Adenosylmethionine Decarboxylase; Adrenalectomy; Animals; Female; Hepatectomy; Hydrocortisone; Liver; Methionine; Mitoguazone; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Starvation; Thioacetamide | 1977 |
Selective methylation: an incorrect hypothesis.
Topics: Cell-Free System; Escherichia coli; Guanine; Methionine; Methylation; Mutation; N-Glycosyl Hydrolases; RNA, Bacterial; RNA, Transfer; S-Adenosylhomocysteine; tRNA Methyltransferases; Uracil | 1976 |
The influence of DL-methionine on the metabolism of S-adenosylethionine in rats chronically treated with DL-ethionine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Body Weight; Circadian Rhythm; Ethionine; Feeding Behavior; Female; Liver; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
The elevation of cerebral histamine-N-and catechol-O-methyl transferase activities by L-methionine-dl-sulfoximine.
Topics: Animals; Basal Ganglia; Brain; Brain Stem; Catechol O-Methyltransferase; Cerebellum; Cerebral Cortex; Guinea Pigs; Hippocampus; Histamine N-Methyltransferase; Hypothalamus; Kinetics; Male; Mesencephalon; Methionine; Methionine Sulfoximine; Methylation; Methyltransferases; Mice; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1975 |
Methionine metabolism in mammals: S-adenosylhomocysteine hydrolase in rat intestinal mucosa.
Topics: Animals; Hydrolases; Intestinal Mucosa; Intestine, Small; Male; Methionine; Rats; S-Adenosylhomocysteine | 1975 |
Activation of the anaerobic ribonucleotide reductase from Escherichia coli by S-adenosylmethionine.
Topics: Anaerobiosis; Cytidine Triphosphate; Deoxyadenosines; Enzyme Activation; Escherichia coli; Kinetics; Methionine; Models, Biological; Oxidation-Reduction; Ribonucleotide Reductases; S-Adenosylhomocysteine; S-Adenosylmethionine | 1992 |
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression.
Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1992 |
Prolonged acetaminophen ingestion by mice fed a methionine-limited diet does not affect iron-induced liver lipid peroxidation or S-adenosylmethionine.
Topics: Acetaminophen; Animals; Cysteine; Glutathione; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Male; Methionine; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Superoxide Dismutase | 1992 |
Disruption of thymidylate synthesis and glycine-serine interconversion by L-methionine and L-homocystine in Raji cells.
Topics: Amino Acids; Burkitt Lymphoma; Glycine; Glycine Hydroxymethyltransferase; Homocystine; Humans; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tetrahydrofolates; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1990 |
S-adenosylmethionine and S-adenosylhomocysteine transitions in encysting Physarum flavicomum amoebae.
Topics: Chromatography, High Pressure Liquid; Methionine; Physarum; S-Adenosylhomocysteine; S-Adenosylmethionine | 1990 |
Cobalamin neuropathy. Is S-adenosylhomocysteine toxicity a factor?
Topics: Animals; Brain Chemistry; Chiroptera; Chromatography, High Pressure Liquid; Homocysteine; Liver; Methionine; Neuromuscular Diseases; S-Adenosylhomocysteine; S-Adenosylmethionine; Valine; Vitamin B 12 Deficiency | 1990 |
Biochemical analysis of the role of transmethylation in the methionine dependence of tumor cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biogenic Polyamines; Cell Division; Culture Media; Cystathionine beta-Synthase; Homocysteine; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Phenotype; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1989 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Effect of toluene on rat synaptosomal phospholipid methylation and membrane fluidity.
Topics: Animals; Brain; Male; Membrane Fluidity; Methionine; Methionine Adenosyltransferase; Methylation; Norepinephrine; Phosphatidylethanolamines; Phospholipids; Propranolol; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Synaptosomes; Toluene | 1989 |
Effect of dietary methyl group deficiency on one-carbon metabolism in rats.
Topics: Amino Acids; Animals; Carbon; Choline Deficiency; Diet; Glycine N-Methyltransferase; Liver; Male; Methionine; Methylation; Methyltransferases; Organ Size; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Weight Gain | 1989 |
Regulation of 5-methyltetrahydrofolate synthesis.
Topics: Animals; Liver; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1989 |
Effects of nitrous oxide inactivation of vitamin B12 and of methionine on folate coenzyme metabolism in rat liver, kidney, brain, small intestine and bone marrow.
Topics: Animals; Bone Marrow; Brain; Folic Acid; Intestine, Small; Kidney; Liver; Male; Methionine; Nitrous Oxide; Organ Specificity; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1989 |
Evidence for altered methionine methyl-group utilization in the diabetic rat's brain.
Topics: Administration, Oral; Animals; Brain; Caseins; Diabetes Mellitus, Experimental; Diet; Female; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptozocin; Time Factors | 1988 |
Methionine metabolism in mammals. Adaptation to methionine excess.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Glutathione; Liver; Male; Methionine; Methionine Adenosyltransferase; Methyltransferases; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine | 1986 |
Growth support and toxicity of homocysteine and its effects on methionine metabolism in non-transformed and chemically transformed C3H/10T1/2 cells.
Topics: Animals; Cell Division; Cell Line; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Homocystine; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured | 1988 |
S-adenosyl-L-methionine protects the hippocampal CA1 neurons from the ischemic neuronal death in rat.
Topics: Animals; Cell Membrane; Cell Survival; Cytidine Diphosphate Choline; Hippocampus; Ischemic Attack, Transient; Male; Methionine; Methylation; Necrosis; Nerve Degeneration; Neurons; Phosphatidylcholines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
Hepatic DNA methylation and liver tumor formation in male C3H mice fed methionine- and choline-deficient diets.
Topics: Animals; Body Weight; Choline; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Mice; Mice, Inbred C3H; Organ Size; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1986 |
S-adenosylmethionine: studies on chemical and enzymatic synthesis.
Topics: Adenosylhomocysteinase; Enzymes, Immobilized; Hydrolases; Kinetics; Magnetic Resonance Spectroscopy; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 1987 |
Methionine metabolism in isolated perfused livers from rats fed on zinc-deficient and restricted diets.
Topics: Animals; Butyrates; Cystathionine; Diet; Homocysteine; In Vitro Techniques; Liver; Male; Methionine; Perfusion; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1986 |
Resistance to multiple adenine nucleoside and methionine analogues in mutant murine lymphoma cells with enlarged S-adenosylmethionine pools.
Topics: Adenosine; Animals; Cells, Cultured; Drug Resistance; Homocysteine; Kinetics; Lymphoma; Methionine; Methionine Adenosyltransferase; Mice; Mutation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1986 |
Disposition of homocysteine in rat hepatocytes and in nontransformed and malignant mouse embryo fibroblasts following exposure to inhibitors of S-adenosylhomocysteine catabolism.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Adenosylhomocysteinase; Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Methionine; Rats; S-Adenosylhomocysteine | 1986 |
3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Colonic Neoplasms; Humans; Hydrolases; Kinetics; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylhomocysteine; Uridine | 1986 |
Effect of zinc deficiency on methionine metabolism, methylation reactions and protein synthesis in isolated perfused rat liver.
Topics: Amino Acids, Sulfur; Animals; Chromatography; DNA; In Vitro Techniques; Liver; Male; Methionine; Methylation; Microsomes, Liver; Perfusion; Phospholipids; Protein Biosynthesis; Rats; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc | 1985 |
S-Adenosylhomocysteine hydrolase deficiency in cysteine auxotrophs of Tetrahymena thermophila.
Topics: Adenosylhomocysteinase; Animals; Carbon-Oxygen Lyases; Culture Media; Cysteine; Hydrolases; Lyases; Methionine; Mutation; N-Glycosyl Hydrolases; S-Adenosylhomocysteine; Tetrahymena | 1985 |
Comparative studies on the methionine synthesis in sheep and rat tissues.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Female; Kidney; Liver; Methionine; Methyltransferases; Muscles; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sheep; Tissue Distribution | 1985 |
Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine.
Topics: Azacitidine; Cell Line; Culture Media; DNA; Dose-Response Relationship, Drug; Floxuridine; Fragile X Syndrome; Homocysteine; Humans; Karyotyping; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Chromosome Aberrations | 1983 |
Effects of a methyl-deficient diet on rat liver phosphatidylcholine biosynthesis.
Topics: Animals; Choline Deficiency; Diacylglycerol Cholinephosphotransferase; Diet; Female; Liver; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Reduced availability of endogenously synthesized methionine for S-adenosylmethionine formation in methionine-dependent cancer cells.
Topics: Cell Division; Cell Line; Cell Transformation, Viral; Homocysteine; Humans; Methionine; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1982 |
Reduced free-methionine in methionine-dependent SV40-transformed human fibroblasts synthesizing apparently normal amounts of methionine.
Topics: Cell Line; Cell Transformation, Viral; Cells, Cultured; Humans; Methionine; Protein Biosynthesis; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1983 |
Elevated overall rates of transmethylation in cell lines from diverse human tumors.
Topics: Adenosylhomocysteinase; Cell Line; Homocysteine; Humans; Hydrolases; Methionine; Methylation; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1984 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.
Topics: Adenosine; Aspartic Acid; Erythrocyte Membrane; Erythrocytes; Homocysteine; Humans; Membrane Proteins; Methionine; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines.
Topics: Cell Line; Homocysteine; Humans; Methionine; Models, Biological; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Metabolic conversion of neplanocin A to S-neplanocylmethionine by mouse L 929 cells.
Topics: Adenosine; Animals; Biotransformation; L Cells; Methionine; Methyltransferases; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity | 1984 |
Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet.
Topics: Animals; Cell Nucleus; Choline Deficiency; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Differential membrane protein carboxyl-methylation of intact human erythrocytes by exogenous methyl donors.
Topics: Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Humans; Hydrolysis; Membrane Proteins; Methionine; Methylation; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Methionine metabolism in mammals. Distribution of homocysteine between competing pathways.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Male; Methionine; Methyltransferases; Models, Biological; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
S-adenosyl-L-methionine synthetase from human erythrocytes: role in the regulation of cellular S-adenosylmethionine levels.
Topics: Cytosol; Erythrocytes; Humans; Kinetics; Methionine; Methionine Adenosyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Transferases | 1983 |
Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Lung; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Testis; Tissue Distribution; Vitamin B 12 Deficiency | 1983 |
Characteristics of protein carboxyl methylation in the rat hypothalamus.
Topics: Animals; Hypothalamus; Kinetics; Male; Methionine; Methylation; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Synaptosomes; Tritium | 1982 |
Methionine metabolism in mammals: concentration of metabolites in rat tissues.
Topics: Amino Acids, Sulfur; Animals; Cysteine; Cystine; Dietary Proteins; Homeostasis; Homocysteine; Male; Methionine; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfhydryl Compounds; Tissue Distribution | 1982 |
The biosynthesis of polyamines in the brain of audiogenic seizure-susceptible and -resistant deermice.
Topics: Acoustic Stimulation; Animals; Brain; Chromatography, High Pressure Liquid; Methionine; Peromyscus; Polyamines; Putrescine; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures; Spermidine; Spermine | 1981 |
S-Adenosylmethionine and S-adenosylhomocystein metabolism in isolated rat liver. Effects of L-methionine, L-homocystein, and adenosine.
Topics: Adenosine; Animals; DNA; Female; Histones; Homocysteine; Kinetics; Liver; Methionine; Perfusion; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Prevention of neural tube defects by and toxicity of L-homocysteine in cultured postimplantation rat embryos.
Topics: Adenosylhomocysteinase; Animals; Catalase; Copper; Copper Sulfate; Culture Techniques; Drug Interactions; Embryonic and Fetal Development; Embryonic Development; Female; Homocysteine; Homocystine; Hydrolases; Methionine; Neural Tube Defects; Oxidation-Reduction; Pregnancy; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Stereoisomerism; Teratogens; Vitamin B 12 | 1994 |
The methyltransferase inhibitor Neplanocin A interferes with influenza virus replication by a mechanism different from that of 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Drug Synergism; Homocysteine; Hydrolases; Influenza A virus; Methionine; Methyltransferases; RNA Caps; RNA, Viral; S-Adenosylhomocysteine; Tubercidin; Viral Proteins; Virus Replication | 1995 |
Electrostatic activation of Escherichia coli methionine repressor.
Topics: Apoproteins; Bacterial Proteins; Base Sequence; Chemical Phenomena; Chemistry, Physical; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydrogen Bonding; Methionine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Operator Regions, Genetic; Protein Binding; Protein Conformation; Repressor Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1994 |
S-adenosylmethionine metabolism in herpes simplex virus type 2-infected cells.
Topics: Animals; Biotransformation; Cell Line, Transformed; Cells, Cultured; Embryo, Mammalian; Kinetics; Methionine; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Simplexvirus; Sulfur Radioisotopes; Tritium | 1993 |
Effect of nitrous oxide exposure on maternal and embryonic S-adenosylmethionine levels and ornithine decarboxylase activity.
Topics: Animals; Embryo, Mammalian; Female; Liver; Methionine; Nitrous Oxide; Ornithine Decarboxylase; Pregnancy; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1993 |
Ethynylestradiol protection against methyl insufficiency in castrated male Wistar/Furth rats fed a methionine-choline-deficient diet.
Topics: Animals; Body Weight; Castration; Choline Deficiency; Ethinyl Estradiol; Liver; Lung; Male; Methionine; Organ Size; Pancreas; Rats; Rats, Inbred WF; S-Adenosylhomocysteine; S-Adenosylmethionine | 1993 |
Crithidia luciliae: effect of purine starvation on S-adenosyl-L-methionine uptake and protein methylation.
Topics: Adenosine; Animals; Crithidia; Cycloheximide; Decarboxylation; Methionine; Methylation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Purines; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1995 |
Carbon flow through the hepatic folate-dependent one-carbon pool is not altered in vitamin A-deficient rats.
Topics: Animals; Carbon; Carbon Radioisotopes; Diterpenes; Folic Acid; Liver; Male; Methionine; Random Allocation; Rats; Rats, Sprague-Dawley; Retinyl Esters; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tritium; Vitamin A; Vitamin A Deficiency | 1996 |
Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Apoptosis; Cell Division; Deoxyuracil Nucleotides; Ethanol; Folic Acid; Homocysteine; Liver; Male; Methionine; Proliferating Cell Nuclear Antigen; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Thymine Nucleotides | 1996 |
Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Erythrocytes; Homocysteine; Humans; Mercaptopurine; Methionine; Methotrexate; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine | 1996 |
Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Homocysteine; Humans; Kinetics; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1996 |
Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
Topics: Base Sequence; Crystallography, X-Ray; Cytosine; DNA; DNA Methylation; DNA-Cytosine Methylases; Methionine; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Protein Conformation; Protons; S-Adenosylhomocysteine | 1996 |
Transport of S-adenosylmethionine in isolated rat liver mitochondria.
Topics: Animals; Biological Transport; Carrier Proteins; Kinetics; Methionine; Mitochondria, Liver; Phospholipids; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 1997 |
Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Administration, Oral; Adult; Female; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates | 1997 |
Measurement of plasma S-adenosylmethionine and S-adenosylhomocysteine as their fluorescent isoindoles.
Topics: Administration, Oral; Chromatography, High Pressure Liquid; Cyanides; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Indoles; Methionine; Naphthalenes; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine; Temperature | 1998 |
In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.
Topics: Adenosine; Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Kinetics; Membrane Proteins; Methionine; Nucleoside Transport Proteins; Polyamines; S-Adenosylhomocysteine; Thionucleosides; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 2001 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Wy-14,643-induced hypomethylation of the c-myc gene in mouse liver.
Topics: Administration, Oral; Animals; Blotting, Southern; Cell Division; Cell Nucleus; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Genes, myc; Injections, Intraperitoneal; Liver; Methionine; Mice; Mice, Inbred Strains; Peroxisome Proliferators; Proliferating Cell Nuclear Antigen; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2001 |
Retinoid compounds activate and induce hepatic glycine N-methyltransferase in rats.
Topics: Animals; Enzyme Activation; Enzyme Induction; Glycine N-Methyltransferase; Liver; Male; Methionine; Methylation; Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tretinoin | 2001 |
Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in mouse liver and the effect of methionine on their concentrations.
Topics: Animals; Chromatography, High Pressure Liquid; Liver; Methionine; Mice; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet | 2001 |
Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice.
Topics: Animals; Biomarkers; Choline Deficiency; Diet; DNA Methylation; Folic Acid Deficiency; Intestinal Neoplasms; Methionine; Mice; Neoplasms; Precancerous Conditions; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
S-adenosyl-methionine-induced apoptosis in PC12 cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Cell Differentiation; Culture Media, Conditioned; DNA Fragmentation; Intracellular Fluid; L-Lactate Dehydrogenase; Methionine; Neurons; Parkinsonian Disorders; PC12 Cells; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Hepatic glycine N-methyltransferase is up-regulated by excess dietary methionine in rats.
Topics: Animals; Dietary Proteins; Dose-Response Relationship, Drug; Glycine N-Methyltransferase; Kidney; Liver; Male; Methionine; Methyltransferases; Pancreas; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Up-Regulation; Weight Gain | 2002 |
Acute valproate administration impairs methionine metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Anticonvulsants; Betaine-Homocysteine S-Methyltransferase; Female; Folic Acid; Glutathione; Glutathione Disulfide; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methyltransferases; Models, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Teratogens; Valproic Acid; Vitamin B 6 | 2002 |
Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine.
Topics: Adult; Carbon Isotopes; Homocysteine; Humans; Kinetics; Liver Cirrhosis, Alcoholic; Male; Methionine; Methylation; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tritium | 2002 |
S-adenosylmethionine transport in Rickettsia prowazekii.
Topics: Adenosine; Anion Transport Proteins; Bacterial Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Escherichia coli; Ethionine; Ethylmaleimide; Methionine; Rickettsia prowazekii; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice.
Topics: Alkynes; Amino Acids; Animals; Betaine; Biological Transport; Cystathionine; Cystathionine gamma-Lyase; Cysteine Dioxygenase; Dioxygenases; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Glycine; Liver; Methionine; Mice; Mice, Inbred ICR; Oxygenases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine | 2003 |
Altered methionine metabolism in long living Ames dwarf mice.
Topics: Aging; Animals; Brain; Cystathionine beta-Synthase; DNA Methylation; Glycine N-Methyltransferase; Liver; Male; Methionine; Methionine Adenosyltransferase; Methyltransferases; Mice; Mice, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Anti-HIV-1 activity of 3-deaza-adenosine analogs. Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners.
Topics: Adenosylhomocysteinase; Anti-HIV Agents; Cell Line; Enzyme Inhibitors; HIV Core Protein p24; HIV-1; Humans; Hydrolases; Inhibitory Concentration 50; Kinetics; Lymphoma, T-Cell; Methionine; Methylation; Models, Molecular; Phosphorylation; Placenta; Protein Binding; S-Adenosylhomocysteine; T-Lymphocytes; Thermodynamics; Tubercidin | 2003 |
Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats.
Topics: Administration, Oral; Animals; Betaine; Ethanol; Hepatocytes; Male; Methionine; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Utilization of S-adenosylmethionine by micro-organisms.
Topics: Adenine; Bacteria; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur | 1962 |
Increased plasma homocysteine and S-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis.
Topics: Child; Cystic Fibrosis; Female; Homocysteine; Humans; Male; Methionine; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylhomocysteine; Severity of Illness Index | 2003 |
A mathematical model of the methionine cycle.
Topics: Animals; Computational Biology; Cystathionine; Homocysteine; Methionine; Models, Biological; S-Adenosylhomocysteine; S-Adenosylmethionine | 2004 |
Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.
Topics: Amino Acids, Sulfur; Carcinoma; Cell Line, Tumor; Cell Survival; Cystathionine; Cysteine; DNA; Glutathione; Humans; Lung Neoplasms; Methionine; Nicotiana; S-Adenosylhomocysteine; S-Adenosylmethionine; Smoke; Time Factors | 2004 |
Uteroplacental insufficiency alters DNA methylation, one-carbon metabolism, and histone acetylation in IUGR rats.
Topics: Acetylation; Animals; Carbon; Chromatin; Cystathionine beta-Synthase; Disease Models, Animal; Disease Susceptibility; DNA Methylation; Enzyme Induction; Female; Fetal Growth Retardation; Gene Expression Regulation, Developmental; Gestational Age; Histones; Liver; Methionine; Methionine Adenosyltransferase; Placental Circulation; Placental Insufficiency; Pregnancy; Protein Processing, Post-Translational; Rats; S-Adenosylhomocysteine | 2004 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
Congenital heart defects and abnormal maternal biomarkers of methionine and homocysteine metabolism.
Topics: Adult; Arkansas; Biomarkers; Case-Control Studies; Female; Heart Defects, Congenital; Homocysteine; Humans; Infant, Newborn; Life Style; Methionine; Pregnancy; Registries; Risk Factors; S-Adenosylhomocysteine | 2005 |
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis.
Topics: Analysis of Variance; Animals; Bile Ducts; Cholestasis; Cysteine; Glutathione; Homocysteine; Ligation; Liver; Liver Cirrhosis, Biliary; Male; Methionine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2005 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Homocysteine, a risk factor for atherosclerosis, biphasically changes the endothelial production of kynurenic acid.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Excitatory Amino Acid Antagonists; Glycine; Homocysteine; In Vitro Techniques; Injections, Intraperitoneal; Kynurenic Acid; Leucine; Male; Methionine; Phenylalanine; Pipecolic Acids; Rats; Rats, Wistar; Risk Factors; S-Adenosylhomocysteine | 2005 |
Diet-dependent survival of protein repair-deficient mice.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Brain; Eating; Folic Acid; Methionine; Mice; Mice, Mutant Strains; Protein D-Aspartate-L-Isoaspartate Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures; Survival Rate | 2005 |
Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biomarkers; Choline; Chromatography, High Pressure Liquid; Disease Models, Animal; Fatty Liver; Female; Hepatitis; Heterozygote; Methionine; Mice; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Severity of Illness Index; Up-Regulation | 2006 |
The 5th workshop on the assessment of adequate intake of dietary amino acids: general discussion 1.
Topics: Amino Acids; Animals; Creatine; Cysteine; Diet; Glutathione; Homocysteine; Humans; Methionine; Nutritional Requirements; S-Adenosylhomocysteine; S-Adenosylmethionine | 2006 |
Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats.
Topics: Adenine; Animals; Cystathionine beta-Synthase; Diet; Dose-Response Relationship, Drug; Enzyme Activation; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 2006 |
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.
Topics: Adolescent; Autistic Disorder; Catechol O-Methyltransferase; Child; Child, Preschool; DNA Primers; Female; Gene Frequency; Glutathione Transferase; Humans; Male; Membrane Transport Proteins; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidative Stress; Reduced Folate Carrier Protein; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins | 2006 |
Effect of vitamin B6 deficiency on S-adenosylhomocysteine hydrolase activity as a target point for methionine metabolic regulation.
Topics: Adenosylhomocysteinase; Analysis of Variance; Animals; Body Weight; Homocysteine; Liver; Male; Methionine; Random Allocation; Rats; Rats, Wistar; S-Adenosylhomocysteine; Vitamin B Deficiency | 2006 |
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.
Topics: Animals; Brain; Disease Models, Animal; Embryo, Mammalian; Female; Ferredoxin-NADP Reductase; Folic Acid; Heart; Homocysteine; Hyperhomocysteinemia; Kidney; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Supranormal dietary folic acid supplementation: effects on methionine metabolism in weanling rats.
Topics: Animals; Biomarkers; Dietary Supplements; DNA Methylation; Folic Acid; Homocysteine; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamins; Weaning | 2007 |
Accumulation of altered aspartyl residues in erythrocyte proteins from patients with Down's syndrome.
Topics: Case-Control Studies; Child; Down Syndrome; Erythrocyte Aging; Erythrocyte Membrane; Herpesvirus 4, Human; Humans; Isoaspartic Acid; Lymphocytes; Membrane Proteins; Methemoglobin; Methionine; Methylation; Oxidative Stress; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Recombinant Proteins; S-Adenosylhomocysteine | 2007 |
Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.
Topics: Alanine Transaminase; Animals; ATPases Associated with Diverse Cellular Activities; Chromosome Mapping; Disease Models, Animal; Down-Regulation; Embryo, Mammalian; Female; Gene Expression; Gene Expression Profiling; Glycine N-Methyltransferase; Glycogen; Glycogen Storage Disease; Hepatitis, Chronic; Homocysteine; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Plasma S-adenosylhomocysteine is a better biomarker of atherosclerosis than homocysteine in apolipoprotein E-deficient mice fed high dietary methionine.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Body Weight; Diet; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Male; Methionine; Mice; S-Adenosylhomocysteine; Vitamin B 12; Vitamin B 6 | 2008 |
Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling.
Topics: 5' Untranslated Regions; Base Sequence; Binding Sites; Coenzymes; Conserved Sequence; Gene Expression Regulation; Homocysteine; Kinetics; Methionine; Nucleic Acid Conformation; RNA; RNA, Bacterial; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Taurine supplementation improves the utilization of sulfur-containing amino acids in rats continually administrated alcohol.
Topics: Alcohol Drinking; Animals; Cysteine; Ethanol; Methionine; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine | 2009 |
In vitro formation of homocysteine in whole blood in the presence of anticoagulants.
Topics: Anticoagulants; Blood Chemical Analysis; Catalysis; Citric Acid; Edetic Acid; Homocysteine; Humans; In Vitro Techniques; Iron; Methionine; S-Adenosylhomocysteine | 2008 |
Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet.
Topics: Animals; Brain; Diet, Reducing; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Folic Acid Deficiency; Homocysteine; Male; Methionine; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Regulatory Factor X Transcription Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Transcription Factors | 2008 |
Methionine metabolism in an animal model of sepsis.
Topics: Animals; Cysteine; Disease Models, Animal; Glutathione; Homocysteine; Lipopolysaccharides; Male; Methionine; Oxidation-Reduction; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis | 2008 |
Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells.
Topics: Cell Line; Cells, Cultured; Disulfides; Epithelial Cells; Humans; Lung; Metabolic Networks and Pathways; Methionine; Methylation; Methyltransferases; Models, Biological; Oxidation-Reduction; Oxidative Stress; Peroxides; Respiratory Mucosa; S-Adenosylhomocysteine; S-Adenosylmethionine | 2009 |
Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine.
Topics: Animals; Brain; Cognition Disorders; Dietary Supplements; Folic Acid Deficiency; Homocystine; Lecithins; Male; Maze Learning; Methionine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone.
Topics: Aged; Animals; Bone and Bones; Collagen; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methionine; Myocardium; Osteoporosis; Porosity; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Stress, Mechanical | 2009 |
Hypohomocysteinemic effect of cysteine is associated with increased plasma cysteine concentration in rats fed diets low in protein and methionine levels.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Choline; Cystathionine beta-Synthase; Cysteic Acid; Cysteine; Diet, Protein-Restricted; Dietary Supplements; Glycine; Homocysteine; Hyperhomocysteinemia; Male; Mercaptoethylamines; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; Soybean Proteins | 2009 |
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Caseins; Cystathionine beta-Synthase; Cysteine; Dietary Proteins; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Glycine; Homocysteine; Liver; Male; Methionine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Weight Gain | 2009 |
Global DNA methylation in the mouse liver is affected by methyl deficiency and arsenic in a sex-dependent manner.
Topics: Animals; Arsenites; Carcinogens; Choline Deficiency; Deoxycytidine; Diet; DNA; DNA Methylation; DNA Modification Methylases; Female; Folic Acid Deficiency; Gene Expression Regulation, Enzymologic; Isoenzymes; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Characteristics; Sodium Compounds | 2011 |
Some more comments on 'folate deficiency in chronic pancreatitis'.
Topics: Folic Acid Deficiency; Glycine N-Methyltransferase; Homocysteine; Humans; Metabolic Networks and Pathways; Methionine; Pancreatitis, Chronic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2010 |
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
The effects of dietary supplementation of methionine on genomic stability and p53 gene promoter methylation in rats.
Topics: Animals; Dietary Supplements; DNA Methylation; Doxorubicin; Genes, p53; Genomic Instability; Glutathione; Kidney; Male; Methionine; Promoter Regions, Genetic; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
B-vitamin deficiency is protective against DSS-induced colitis in mice.
Topics: Analysis of Variance; Animals; Body Weight; Colitis; Dextran Sulfate; Gene Expression; Glutathione; Homocysteine; Inflammation; Interleukin-10; Kaplan-Meier Estimate; Male; Metabolomics; Methionine; Methylmalonic Acid; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Peroxidase; Pyridoxal Phosphate; S-Adenosylhomocysteine; Severity of Illness Index; Tumor Necrosis Factor-alpha; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2011 |
[Function of luxS gene in sulfurmetabolism of Streptococcus mutans].
Topics: Bacterial Proteins; Biofilms; Carbon-Sulfur Lyases; Culture Media; Culture Techniques; Cysteine; Gene Expression Regulation, Bacterial; Methionine; Microscopy, Confocal; Quorum Sensing; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptococcus mutans; Sulfur | 2011 |
Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function.
Topics: Adenosine Kinase; Adult; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Child; Developmental Disabilities; Family Health; Female; Fibroblasts; Homocysteine; Humans; Liver Diseases; Male; Methionine; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Increased plasma S-adenosyl-homocysteine levels induce the proliferation and migration of VSMCs through an oxidative stress-ERK1/2 pathway in apoE(-/-) mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cell Movement; Cell Proliferation; Dietary Supplements; MAP Kinase Signaling System; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; S-Adenosylhomocysteine | 2012 |
Methionine sulfoxide reductase contributes to meeting dietary methionine requirements.
Topics: Animals; Base Sequence; Diet; DNA Primers; Glycine N-Methyltransferase; Methionine; Methionine Sulfoxide Reductases; Mice; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult | 2012 |
Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease.
Topics: Adenosylhomocysteinase; Animals; Betaine; Copper; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Down-Regulation; Endoplasmic Reticulum Stress; Epigenesis, Genetic; Hepatolenticular Degeneration; Inflammation; Liver; Methionine; Mice; Mice, Inbred C3H; Penicillamine; S-Adenosylhomocysteine | 2013 |
The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Bacillus cereus; Bacterial Proteins; Biotin; Carrier Proteins; Chromatography, Gel; Conserved Sequence; Escherichia coli; Fatty Acids; Genetic Complementation Test; Hydrogen-Ion Concentration; Methionine; Molecular Sequence Data; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2012 |
The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Cholesterol, Dietary; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression; Homocysteine; Hyperhomocysteinemia; Hyperlipidemias; Lipids; Male; Methionine; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2012 |
Elevation of cysteine consumption in tamoxifen-resistant MCF-7 cells.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione; Humans; Membrane Transport Modulators; Methionine; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Tamoxifen; Taurine; Up-Regulation | 2013 |
LC-MS/MS identification of the one-carbon cycle metabolites in human plasma.
Topics: Adult; Chromatography, Liquid; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Multiple Sclerosis; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
Methylation metabolites in amniotic fluid depend on gestational age.
Topics: Adult; Amniotic Fluid; Betaine; Choline; Female; Gestational Age; Humans; Methionine; Methylation; Methyltransferases; Pregnancy; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine | 2013 |
Levels of key enzymes of methionine-homocysteine metabolism in preeclampsia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Female; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Accumulation of altered aspartyl residues in erythrocyte membrane proteins from patients with sporadic amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Erythrocyte Membrane; Female; Humans; Male; Membrane Proteins; Methionine; Methionine Adenosyltransferase; Middle Aged; Oxidation-Reduction; Oxidative Stress; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Reactive Oxygen Species; S-Adenosylhomocysteine | 2013 |
Plasma homocysteine, methionine and S-adenosylhomocysteine levels following high-dose methotrexate treatment in pediatric patients with acute lymphoblastic leukemia or Burkitt lymphoma: association with hepatotoxicity.
Topics: Antimetabolites, Antineoplastic; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Homocysteine; Humans; Liver Function Tests; Male; Methionine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; S-Adenosylhomocysteine | 2014 |
Plasma sulfur amino acids and stearoyl-CoA desaturase activity in two Caucasian populations.
Topics: Adipose Tissue; Aged; Aged, 80 and over; Amino Acids, Sulfur; Cohort Studies; Cross-Sectional Studies; Cystathionine; Cysteine; Diet; Dipeptides; Exercise; Fatty Acids; Female; Glutathione; Homocysteine; Humans; Male; Methionine; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Stearoyl-CoA Desaturase; Surveys and Questionnaires; White People | 2013 |
Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse.
Topics: Animals; Betaine; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Ethanol; Fatty Liver, Alcoholic; Gene Expression Regulation; Homocystinuria; Liver; Methionine; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; PPAR alpha; S-Adenosylhomocysteine; S-Adenosylmethionine | 2014 |
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult | 2014 |
The functions of crucial cysteine residues in the arsenite methylation catalyzed by recombinant human arsenic (III) methyltransferase.
Topics: Arsenic; Arsenites; Cacodylic Acid; Catalysis; Catalytic Domain; Cysteine; Disulfides; Glutathione; Humans; Methionine; Methyltransferases; Mutation; Recombinant Proteins; S-Adenosylhomocysteine; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Whey protein supplementation increases methionine intake but not homocysteine plasma concentration in rats.
Topics: Advanced Oxidation Protein Products; Animals; Biomarkers; Caseins; Dietary Supplements; Glutathione; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Liver; Male; Methionine; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Random Allocation; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Whey Proteins | 2015 |
The effect of a methyl-deficient diet on the global DNA methylation and the DNA methylation regulatory pathways.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Choline Deficiency; Cytosine; Deoxyguanosine; DNA Methylation; Fatty Liver; Gene Expression Regulation, Enzymologic; Liver; Male; Methionine; Mice, Inbred C57BL; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine | 2015 |
Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus.
Topics: Aspergillus fumigatus; Fungal Proteins; Gliotoxin; Methionine; Methylation; S-Adenosylhomocysteine | 2015 |
Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism.
Topics: Animals; Carbon; Chromatin; Epigenesis, Genetic; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver; Methionine; Methylation; Mice; One-Carbon Group Transferases; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Adenosine kinase deficiency: expanding the clinical spectrum and evaluating therapeutic options.
Topics: Adenosine; Adenosine Kinase; Adolescent; Adult; Biomarkers; Child; Child, Preschool; Diet; Female; Humans; Hypoglycemia; Infant; Liver; Liver Diseases; Male; Metabolic Diseases; Methionine; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Young Adult | 2016 |
Effects of Nonpurified and Choline Supplemented or Nonsupplemented Purified Diets on Hepatic Steatosis and Methionine Metabolism in C3H Mice.
Topics: Animals; Choline; Diet; Dietary Fats; Dietary Sucrose; Dietary Supplements; Fatty Liver; Feeding Behavior; Female; Lipid Metabolism; Liver; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine | 2016 |
Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila.
Topics: Aging; Animals; Brain; Down-Regulation; Drosophila melanogaster; Drosophila Proteins; Female; Heterochromatin; Intestines; Intracellular Signaling Peptides and Proteins; Longevity; Male; Methionine; Methylation; S-Adenosylhomocysteine | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
Methionine Metabolites in Patients With Sepsis.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Catheter-Related Infections; Cohort Studies; Female; Homocysteine; Hospital Mortality; Humans; Intraabdominal Infections; Logistic Models; Male; Methionine; Middle Aged; Prognosis; Prospective Studies; Respiratory Tract Infections; S-Adenosylhomocysteine; S-Adenosylmethionine; Sepsis; Skin Diseases, Infectious; Urinary Tract Infections | 2018 |
Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells.
Topics: Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Leucovorin; Methionine; Methylation; Protein Processing, Post-Translational; S-Adenosylhomocysteine | 2018 |
The high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) may explain naked mole-rat's distinct methionine metabolite profile compared to mouse.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Enzyme Activation; Homocysteine; Homocystinuria; Methionine; Mice; Mole Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2018 |
Altered Methionine Metabolism in Cancer Cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Homocysteine; Humans; Methionine; Methylation; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 2019 |
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
Topics: A549 Cells; Animals; Cell Proliferation; Cysteine; Extracellular Space; Female; Gene Knockout Techniques; Hep G2 Cells; Heterografts; Humans; Male; MCF-7 Cells; Methionine; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Protamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tumor Burden | 2019 |
S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling.
Topics: Adenosylhomocysteinase; Animals; ARNTL Transcription Factors; Chromatin; Chromatin Assembly and Disassembly; Circadian Clocks; Circadian Rhythm; CLOCK Proteins; Methionine; Mice; S-Adenosylhomocysteine | 2020 |
Maternal and neonatal one-carbon metabolites and the epigenome-wide infant response.
Topics: Adult; Betaine; Carbon; Choline; Cohort Studies; DNA Methylation; Epigenome; Female; Fetal Blood; Histone Code; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Metabolomics; Methionine; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine | 2022 |
S-adenosyl-L-homocysteine extends lifespan through methionine restriction effects.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Longevity; Methionine; S-Adenosylhomocysteine; Saccharomyces cerevisiae | 2022 |
Association of serum s-adenosylmethionine, s-adenosylhomocysteine, and their ratio with the risk of dementia and death in a community.
Topics: Dementia; Humans; Methionine; Proportional Hazards Models; S-Adenosylhomocysteine; S-Adenosylmethionine | 2022 |
Revisiting One-Carbon Metabolites in Human Breast Milk: Focus on S-Adenosylmethionine.
Topics: Adult; Carbon; Child; Chromatography, Liquid; Female; Homocysteine; Humans; Infant; Methionine; Milk, Human; Racemethionine; S-Adenosylhomocysteine; S-Adenosylmethionine; Tandem Mass Spectrometry | 2023 |