methionine has been researched along with pyridoxal phosphate in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (39.53) | 18.7374 |
| 1990's | 12 (13.95) | 18.2507 |
| 2000's | 13 (15.12) | 29.6817 |
| 2010's | 19 (22.09) | 24.3611 |
| 2020's | 8 (9.30) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benevenga, NJ; Everett, GB; Mitchell, AD | 1 |
| Brown, RR; Leklem, JE; Linkswiler, HM; Rose, DP | 2 |
| Andersson, A; Brattström, L; Hamfelt, A; Hultberg, B; Isaksson, A; Israelsson, B | 1 |
| Leklem, JE | 1 |
| Lapin, IP; Ryzhov, IV | 1 |
| Henderson, JM; Hollins, B; Kutner, MH; Merrill, AH; Scott, SS | 1 |
| Nakamura, KD; O'Connor, ML; Parks, LW; Trewyn, RW | 1 |
| Alpert, NR; Hamrell, BB; Russell, DH; Shiverick, KT | 1 |
| Botsford, JL; Parks, LW | 1 |
| Kagamiyama, H; Matsubara, H; Snell, EE; Wada, H | 1 |
| Ellegaard, J; Esmann, V | 1 |
| Conerly, EB; Mudd, SH; Uhlendorf, BW | 1 |
| Evered, DF; Hargreaves, BM | 1 |
| Heinonen, K | 1 |
| Merricks, DL; Salsbury, RL | 1 |
| Dowhan, W; Snell, EE | 1 |
| Pai, CH | 1 |
| Okuyama, T; Suzuki, T | 1 |
| Steiner, FA | 1 |
| Flavin, M; Guggenheim, S | 1 |
| Barker, HA; Chirpich, TP; Costilow, RN; Zappia, V | 1 |
| Brown, MS; Edwards, WA; Laster, L; Loeb, PM; Mudd, SH | 1 |
| Pittoni, A; Rubaltelli, FF | 1 |
| Beaton, JR; Dirige, OV | 1 |
| Osumi, T; Soda, K | 1 |
| Frimpter, GW; Fuchs, F; Greenberg, AJ; Hilgartner, M | 1 |
| Massieu, GH; Ortega, BG; Pasantes, H; Pérez de la Mora, M; Tapia, R | 1 |
| Bors, W; Elstner, EF; Michel, C; Saran, M | 1 |
| Applegarth, DA; Seccombe, D; Vallance, HD | 1 |
| Douce, R; Droux, M; Ravanel, S | 2 |
| Bostom, AG | 1 |
| Coombs, GH; Edlind, T; McKie, AE; Mottram, JC; Walker, J | 1 |
| Douce, R; Gakière, B; Job, D; Ravanel, S | 1 |
| Han, Q; Hoffman, RM; Lenz, M; Miljkovic, D; Sun, X; Tan, X; Tan, Y; Tang, L; Xu, M | 1 |
| Odekerken, DA; Rakic, M; Sijbrands, EJ; Silberbusch, J; Slaats, EH; Smulders, YM; Stehouwer, CD; Treskes, M | 1 |
| Aras, O; Bignell, M; Hanson, NQ; Tsai, MY; Yang, F | 1 |
| Harrison, DH; Miziorko, HM; Runquist, JA | 1 |
| Esaki, N; Furuichi, M; Inagaki, K; Inoue, H; Kumasaka, T; Motoshima, H; Soda, K; Tamura, T; Tanaka, H; Tanaka, N; Yamamoto, M | 1 |
| Finkelstein, JD | 1 |
| Bosy-Westphal, A; Czech, N; Holzapfel, A; Müller, MJ | 1 |
| NISMAN, B; WIESENDANGER, S | 1 |
| DELAVIER-KLUTCHKO, C; FLAVIN, M; SLAUGHTER, C | 1 |
| LANGER, BW | 1 |
| AXELROD, AE; TRAKATELLIS, AC | 1 |
| COEN, LJ; HILLMAN, RS; JACOBS, FA | 1 |
| INGRAHAM, LL; MAZELIS, M | 1 |
| MAZELIS, M | 1 |
| Frenkel, EP; Hoffman, RM; Li, S; Mitsushima, K; Suginaka, A; Sun, X; Takimoto, A; Tan, Y; Wang, X; Yagi, S; Yang, Z; Yoshioka, T; Zhang, N | 1 |
| Emery, PW; Johnston, K; Obeid, OA | 1 |
| Hartmann, B; Krems, C; Lührmann, PM; Neuhäuser-Berthold, M; Strassburg, A | 1 |
| Cambillau, C; Campanacci, V; Dolzan, M; Johansson, K; Roig-Zamboni, V; Schneider, G; Tegoni, M | 1 |
| Coats, BS; Davis, SR; Gregory, JF; Quinlivan, EP; Scheer, JB; Stacpoole, PW | 1 |
| Bonner, ER; Cahoon, RE; Jez, JM; Knapke, SM | 1 |
| Brancato, R; D'Angelo, A; Fattorini, A; Lattanzio, R; Ramoni, A; Sampietro, F | 1 |
| Banavara, DS; Rankin, SA; Wolle, DD | 1 |
| Guo, KP; Jia, XM; Kai, L; Li, X; Ma, XH; Ma, Y; Xu, XH; Zhao, WF | 1 |
| Chang, CC; Chang, JH; Chien, YW; Huang, SY; Tsen, JH; Yang, HT | 1 |
| Bosma, JP; Klip, H; Nooij, LS; van de Leur, JJ; van Eyck, J | 1 |
| Benetou, V; Boeing, H; Boutron-Ruault, MC; Bueno-de-Mesquita, B; Chuang, SC; Clavel-Chapelon, F; Crowe, F; Duell, EJ; Gurrea, AB; Huerta, JM; Jenab, M; Jeurnink, S; Johansen, D; Kaaks, R; Khaw, KT; Larrañaga, N; Manjer, J; Michaud, DS; Midttun, Ø; Molina-Montes, E; Morois, S; Naska, A; Olsen, A; Overvad, K; Palli, D; Panico, S; Peeters, PH; Riboli, E; Rodriguez, L; Romieu, I; Sacerdote, C; Sieri, S; Skeie, G; Slimani, N; Stolzenberg-Solomon, R; Sund, M; Teucher, B; Tjønneland, A; Trichopoulou, A; Tumino, R; Ueland, PM; Vineis, P; Vollset, SE; Wareham, N; Weikert, C; Ye, W | 1 |
| Coats, B; Gregory, JF; Lamers, Y; Quinlivan, EP; Ralat, M; Stacpoole, PW | 1 |
| Benight, NM; Burrin, DG; Chacko, S; da Silva, VR; Gregory, JF; Marini, JC; Stabler, SP; Stoll, B | 1 |
| Begley, TP; Ealick, SE; Krishnamoorthy, K; Tran, TH | 1 |
| Böttcher, B; Derrer, B; Gengenbacher, M; Guédez, G; Hipp, K; Kappes, B; Sinning, I; Tews, I; Windeisen, V | 1 |
| Chory, J; Dai, X; Guo, Y; Ljung, K; Noel, JP; Novák, O; Zhao, Y; Zheng, Z | 1 |
| Kang, S; Wu, W; Zhang, D | 1 |
| Guo, Z; Song, H; Xu, R | 1 |
| Brody, LC; Brosnan, JT; Brosnan, ME; Deac, OM; Fan, R; Gibney, ER; Laird, E; Midttun, Ø; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Anufrieva, N; Demidkina, T; Kulikova, V; Morozova, E; Nikulin, A; Revtovich, S | 1 |
| Hayashi, M; Hirose, Y; Inagaki, J; Inagaki, K; Kudou, D; Kusaka, C; Nemoto, M; Okada, A; Okajima, T; Okugochi, T; Soda, K; Tamura, T; Yamamoto, K | 1 |
| Stone, E; Yan, W; Zhang, YJ | 1 |
| Aguera, K; Berlier, W; Bourgeaux, V; Gay, F; Godfrin, Y; Honnorat, J; Horand, F; Maucort-Boulch, D; Sénéchal, K; Tainturier, A | 1 |
| Harada, S; Karaki, T; Nakazawa, T; Nozaki, T; Sato, D; Shiba, T; Yamagata, W | 1 |
| Gupta, R; Laxman, S; Srinivasan, R; Walvekar, AS | 1 |
| Anufrieva, NV; Bazhulina, NP; Belyi, YF; Demidkina, TV; Hayashi, H; Kotlov, MI; Koval, VS; Kulikova, VV; Morozova, EA; Revtovich, SV | 1 |
| Bhardwaj, M; Cui, Z; Ducho, C; Lemke, A; Liu, X; Niro, G; Overbay, J; Thorson, JS; Van Lanen, SG; Wang, X; Wiegmann, D; Zhang, Y | 1 |
| Aarsand, AK; Aguilera, P; Brunet, M; Deulofeu, R; García-Villoria, J; Gómez-Gómez, À; Pozo, OJ; Sandberg, S; To-Figueras, J; Wijngaard, R | 1 |
| Handa, H; Inagaki, K; Kudo, D; Murota, M; Okawa, A; Shiba, T; Tamura, T; Yasuda, E | 1 |
| Anufrieva, NV; Demidkina, TV; Faleev, NG; Fedorova, OS; Gogoleva, OI; Kuznetsov, NA; Kuznetsova, AA; Morozova, EA; Tsvetikova, MA | 1 |
| Bandyopadhyay, P; Biswas, R; Dutta, S; Laxman, S; Pramanick, I; Ps, S; Rajmani, RS; Singh, A; Singh, S; Sreedharan, S | 1 |
| El Baze, A; Knizia, D; Lakhssassi, A; Lakhssassi, N; Meksem, J; Meksem, K | 1 |
| Bazhulina, NP; Demidkina, TV; Koval, VS; Kulikova, VV; Lyfenko, AD; Morozova, EA; Revtovich, SV | 1 |
| Briozzo, P; Chen, X; Ferchaud, N; Machover, D; Simonson, T | 1 |
4 review(s) available for methionine and pyridoxal phosphate
| Article | Year |
|---|---|
Vitamin B-6: a status report.
Topics: Erythrocytes; Humans; Liver; Methionine; Nutrition Assessment; Nutritional Status; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Transaminases; Tryptophan | 1990 |
[Endogenous convulsants (review)].
Topics: Amino Acids; Animals; Carbolines; Cats; Cerebral Cortex; Convulsants; Cysteic Acid; Cysteine; Disease Models, Animal; Dogs; Estrogens; Folic Acid; Homocysteine; Kynurenine; Methionine; Mice; Neurotransmitter Agents; Prostaglandins; Pyridoxal Phosphate; Quinolinic Acid; Quinolinic Acids; Rats; Seizures; Spinal Cord | 1986 |
Pathways and regulation of homocysteine metabolism in mammals.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates | 2000 |
Association of vitamin B6, vitamin B12 and methionine with risk of breast cancer: a dose-response meta-analysis.
Topics: Breast Neoplasms; Diet; Dose-Response Relationship, Drug; Female; Humans; Methionine; Pyridoxal Phosphate; Risk; Vitamin B 12; Vitamin B 6 | 2013 |
2 trial(s) available for methionine and pyridoxal phosphate
| Article | Year |
|---|---|
Vitamin B6 requirements of women using oral contraceptives.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Cystathionine; Female; Humans; Methionine; Nutritional Requirements; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency | 1975 |
Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women.
Topics: Adult; Breath Tests; Carbon Isotopes; Cystathionine; Deuterium; Diet; DNA Methylation; Female; Humans; Kinetics; Leucine; Male; Methionine; Methylation; Monocytes; Postprandial Period; Pyridoxal Phosphate; Reproducibility of Results; Severity of Illness Index; Vitamin B 6; Vitamin B 6 Deficiency; Young Adult | 2011 |
80 other study(ies) available for methionine and pyridoxal phosphate
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Methionine transamination and catabolism in vitamin B-6 deficient rats.
Topics: Amination; Animals; Caseins; Cystathionine; Dietary Proteins; Liver; Male; Methionine; Oxidation-Reduction; Phosphatidylcholines; Pyridoxal Phosphate; Rats; Vitamin B 6 Deficiency | 1979 |
Effects of oral contraceptives on tryptophan metabolism and vitamin B6 requirements in women.
Topics: Adult; Contraceptives, Oral; Cystathionine; Female; Humans; Kynurenine; Methionine; Pyridoxal Phosphate; Pyridoxine; Sex Factors; Tryptophan; Vitamin B 6 Deficiency | 1975 |
Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status.
Topics: Adult; Aged; Aging; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Pyridoxal Phosphate; Sex Characteristics; Vascular Diseases; Vitamin B 12 | 1992 |
Vitamin B6 repletion in cirrhosis with oral pyridoxine: failure to improve amino acid metabolism.
Topics: Amino Acids; Female; Humans; Liver Cirrhosis; Male; Methionine; Pyridoxal Phosphate; Pyridoxine | 1989 |
An interaction between S-adenosyl-L-methionine and pyridoxal 5'-phosphate, and its effect on Saccharomyces cerevisiae.
Topics: Carbon Radioisotopes; Cell Division; Kinetics; Methionine; Ornithine; Pyridoxal Phosphate; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Transaminases; Tyrosine Transaminase | 1973 |
Polyamine synthesis during initial phases of stress-induced cardiac hypertrophy.
Topics: Adaptation, Physiological; Animals; Butylamines; Carboxy-Lyases; Cardiomegaly; Heart Ventricles; Methionine; Myocardium; Organ Size; Ornithine; Polyamines; Pulmonary Artery; Pyridoxal Phosphate; Rabbits; RNA; S-Adenosylmethionine; Spermidine; Spermine; Stress, Physiological | 1971 |
Role of S-adenosylmethionine in methionine biosynthesis in yeast.
Topics: Adenine Nucleotides; Carbon Isotopes; Cell-Free System; Culture Media; Escherichia coli; Ethanol; Flavin-Adenine Dinucleotide; Hexosephosphates; Homocysteine; Magnesium; Methionine; NAD; Nucleosides; Pyridoxal Phosphate; Saccharomyces; Serine | 1967 |
The chemical structure of tryptophanase from Escherichia coli. II. The structure of tryptophanase monomer.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Ammonium Sulfate; Binding Sites; Borohydrides; Carbon Isotopes; Carboxypeptidases; Chemical Precipitation; Crystallization; Culture Media; Cyanogen Bromide; Escherichia coli; Hydro-Lyases; Indoles; Iodoacetates; Macromolecular Substances; Methionine; Molecular Weight; Peptides; Pyridoxal Phosphate; Pyruvates; Tryptophan | 1972 |
Folate activity of human lymphocytes determined by measurement of serine synthesis.
Topics: Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Citric Acid Cycle; Folic Acid; Folic Acid Deficiency; Formates; Glucose; Glycine; Humans; In Vitro Techniques; Lymphocytes; Methionine; Methods; Protein Binding; Pyridoxal Phosphate; RNA; Serine; Tetrahydrofolates | 1973 |
Homocystinuria: studies in tissue culture.
Topics: Culture Techniques; Fibroblasts; Heterozygote; Homocysteine; Homocystine; Homocystinuria; Humans; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Oxidoreductases; Parents; Proteins; Pyridoxal Phosphate; Pyridoxine; Serine; Skin; Stimulation, Chemical; Tetrahydrofolates | 1973 |
Metabolism of omega-amino acids by rat tissues in vitro.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminocaproates; Aminoisobutyric Acids; Animals; Brain; Caprylates; Cyclohexanecarboxylic Acids; Glycine; Intestinal Mucosa; Kidney; Kinetics; Liver; Male; Methionine; Pyridoxal Phosphate; Rats; Schiff Bases; Spectrophotometry, Ultraviolet; Valerates; Valine | 1973 |
Studies on cystathionase activity in rat liver and brain during development. Effects of hormones and amino acids in vivo.
Topics: Animals; Animals, Newborn; Brain; Cystathionine; Female; Fetus; Homoserine; Liver; Lyases; Methionine; Pregnancy; Pyridoxal Phosphate; Rats; Thyroxine; Time Factors; Triamcinolone | 1973 |
Involvement of vitamin B6 in the dethiomethylation of methionine by rumen microorganisms.
Topics: Alcohols; Ammonia-Lyases; Anaerobiosis; Animals; Bacteria; Carbon Radioisotopes; Cell-Free System; Chromatography, Gas; Drug Antagonism; Eukaryota; Fermentation; Gastric Juice; Methionine; Pyridoxal; Pyridoxal Phosphate; Pyridoxine; Rumen | 1974 |
D-serine dehydratase from Escherichia coli. II. Analytical studies and subunit structure.
Topics: Alkylation; Binding Sites; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cystine; Detergents; Electrophoresis; Escherichia coli; Hydro-Lyases; Hydrogen-Ion Concentration; L-Serine Dehydratase; Methionine; Molecular Weight; Nitrobenzenes; Oxidation-Reduction; Pyridoxal Phosphate; Spectrophotometry; Sulfides; Trypsin; Ultracentrifugation | 1970 |
Biosynthesis of biotin: synthesis of 7,8-diaminopelargonic acid in cell-free extracts of Escherichia coli.
Topics: Amines; Biological Assay; Biotin; Cell-Free System; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Dialysis; Enzyme Repression; Escherichia coli; Fatty Acids; Ligases; Methionine; Mutation; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Spectrophotometry; Sulfates; Transaminases | 1971 |
[Isolation and estimation of phosphopyridoxyllysine and pyridoxyllysine].
Topics: Alanine; Amino Acids; Aminocaproates; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Lysine; Methionine; Proteins; Pyridoxal Phosphate; Pyridoxine; Valine | 1971 |
L-glutamic acid, gamma-aminobutyric acid and pyridoxal-5'-phosphate at the level of the single unit in rat brain.
Topics: Aminobutyrates; Animals; Brain; Brain Chemistry; Cerebral Cortex; Electrophoresis; Excitatory Amino Acid Antagonists; Glutamates; Hippocampus; Hydroxylamines; Male; Methionine; Microchemistry; Neurons; Oximes; Pyridoxal Phosphate; Rats; Thalamus; Thiosemicarbazones | 1969 |
Cystathionine gamma-synthase. A pyridoxal phosphate enzyme catalyzing rapid exchanges of beta and alpha hydrogen atoms in amino acids.
Topics: Amino Acids; Butyrates; Chemical Phenomena; Chemistry; Cysteine; Homocysteine; Hydro-Lyases; Hydrogen; Ketones; Kinetics; Methionine; Pyridoxal Phosphate; Salmonella; Tritium | 1969 |
Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme.
Topics: Acetone; Amino Acids; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium; Cysteine; Deuterium; Dialysis; Drug Stability; Electrophoresis; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxylamines; Intramolecular Transferases; Iron; Isomerases; Isoniazid; Kinetics; Lysine; Methionine; Methods; Molecular Weight; Nucleosides; Pyridoxal Phosphate; Pyridoxine; Streptomycin; Sulfhydryl Compounds; Temperature; Tritium | 1970 |
Homocystinuria due to cystathionine synthase deficiency: the effect of pyridoxine.
Topics: Adult; Aldehydes; Autoanalysis; Carbon Isotopes; Chromatography; Cysteine; Diet; Diet Therapy; Enzyme Activation; Female; Fibroblasts; Homocystine; Homocystinuria; Humans; Hydro-Lyases; Keto Acids; L-Serine Dehydratase; Liver; Male; Methionine; Pyridoxal Phosphate; Pyridoxine; Serine; Sulfates; Trypsin | 1970 |
Pyridoxalphosphate and non-enzymatic synthesis of methionine.
Topics: Aluminum; Betaine; Catalysis; Chromatography, Thin Layer; Copper; Ferrocyanides; Homocysteine; Hydrogen-Ion Concentration; Methionine; Pyridoxal Phosphate | 1967 |
Factors affecting vitamin B6 requirement in the rat as determined by erythrocyte transaminase activity.
Topics: Alanine Transaminase; Amino Acids; Animals; Diet; Dietary Proteins; Erythrocytes; Feeding Behavior; Hypothalamus; Male; Methionine; Pyridoxal Phosphate; Pyridoxine; Rats; Vitamin B Deficiency | 1969 |
Crystalline amino acid racemase with low substrate specificity.
Topics: Alanine; Amino Acids; Arginine; Butyrates; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Dialysis; Electrophoresis, Disc; Ethionine; Isomerases; Leucine; Lysine; Methionine; Methods; Molecular Weight; Pseudomonas; Pyridoxal Phosphate; Spectrophotometry; Ultracentrifugation | 1969 |
Cystathioninuria: management.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Amniotic Fluid; Child; Child, Preschool; Cystine; Female; Humans; In Vitro Techniques; Intellectual Disability; Liver; Male; Methionine; Middle Aged; Pregnancy; Pyridoxal Phosphate; Pyridoxine; Thrombocytopenia | 1967 |
Free amino acids and glutamate decarboxylase activity in brain of mice during drug-induced convulsions.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Carboxy-Lyases; Glutamates; Glutamine; Hydrazines; Insulin; Methionine; Methionine Sulfoximine; Mice; Pentylenetetrazole; Pyridoxal Phosphate; Seizures; Thiosemicarbazones; Transaminases | 1967 |
Formation of ethylene from methionine. Reactivity of radiolytically produced oxygen radicals and effect of substrate activation.
Topics: Chromatography, Gas; Dose-Response Relationship, Radiation; Ethylenes; Free Radicals; Methionine; Oxygen; Pulse Radiolysis; Pyridoxal Phosphate; S-Adenosylmethionine; Superoxide Dismutase; X-Rays | 1980 |
Are patients with homocystinuria being missed?
Topics: Child; Chromatography, High Pressure Liquid; Diagnosis, Differential; Homocysteine; Homocystinuria; Humans; Methionine; Pyridoxal Phosphate | 1995 |
Methionine biosynthesis in higher plants. I. Purification and characterization of cystathionine gamma-synthase from spinach chloroplasts.
Topics: Alkynes; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Cell Compartmentation; Chloroplasts; Cystathionine; Glycine; Homocysteine; Homoserine; Kinetics; Lyases; Methionine; Molecular Weight; Pargyline; Plant Leaves; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spinacia oleracea | 1995 |
Methionine biosynthesis in higher plants. II. Purification and characterization of cystathionine beta-lyase from spinach chloroplasts.
Topics: Aminobutyrates; Cell Compartmentation; Chloroplasts; Cystathionine; Homocysteine; Kinetics; Lyases; Methionine; Plant Leaves; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Spectrophotometry; Spinacia oleracea | 1995 |
Methionine loading, vitamin B6 status, and premature thromboembolic disease.
Topics: Humans; Methionine; Pyridoxal Phosphate; Pyridoxine; Thromboembolism | 1996 |
The primitive protozoon Trichomonas vaginalis contains two methionine gamma-lyase genes that encode members of the gamma-family of pyridoxal 5'-phosphate-dependent enzymes.
Topics: Amino Acid Sequence; Animals; Carbon-Sulfur Lyases; Cloning, Molecular; Gene Expression; Isoenzymes; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protozoan Proteins; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA; Substrate Specificity; Trichomonas | 1998 |
Cystathionine gamma-synthase from Arabidopsis thaliana: purification and biochemical characterization of the recombinant enzyme overexpressed in Escherichia coli.
Topics: Alkynes; Amino Acid Sequence; Arabidopsis; Binding Sites; Carbon-Oxygen Lyases; Cloning, Molecular; DNA, Complementary; Enzyme Inhibitors; Escherichia coli; Gene Expression; Glycine; Homoserine; Kinetics; Lysine; Macromolecular Substances; Methionine; Molecular Sequence Data; Pyridoxal Phosphate; Recombinant Proteins | 1998 |
High expression, purification, and properties of recombinant homocysteine alpha, gamma-lyase.
Topics: Animals; Carbon-Sulfur Lyases; Cardiovascular Diseases; Chromatography; Cloning, Molecular; Cysteine; Enzyme Stability; Escherichia coli; Homocysteine; Hydrogen-Ion Concentration; Hyperhomocysteinemia; Kinetics; Methionine; Protein Conformation; Protozoan Proteins; Pseudomonas putida; Pyridoxal Phosphate; Recombinant Proteins; Substrate Specificity; Temperature; Trichomonas vaginalis | 1998 |
Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease.
Topics: Administration, Oral; Adult; Aged; Albuminuria; Analysis of Variance; Blood Pressure; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Postmenopause; Premenopause; Pyridoxal Phosphate; Regression Analysis; Risk Factors; Vitamin B 12 | 1999 |
Relation between plasma homocysteine concentration, the 844ins68 variant of the cystathionine beta-synthase gene, and pyridoxal-5'-phosphate concentration.
Topics: Adult; Aged; Cystathionine beta-Synthase; Fasting; Female; Genetic Variation; Genotype; Homocysteine; Humans; Male; Methionine; Middle Aged; Mutagenesis, Insertional; Pyridoxal Phosphate | 1999 |
Rhodobacter sphaeroides phosphoribulokinase: identification of lysine-165 as a catalytic residue and evaluation of the contributions of invariant basic amino acids to ribulose 5-phosphate binding.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Gluconates; Kinetics; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphotransferases (Alcohol Group Acceptor); Pyridoxal Phosphate; Rhodobacter sphaeroides; Ribulosephosphates | 1999 |
Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida.
Topics: Amino Acid Sequence; Binding Sites; Carbon-Sulfur Lyases; Crystallography, X-Ray; Methionine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pseudomonas putida; Pyridoxal Phosphate; Sequence Homology, Amino Acid; X-Ray Diffraction | 2000 |
Plasma folate but not vitamin B(12) or homocysteine concentrations are reduced after short-term vitamin B(6) supplementation.
Topics: Adult; Area Under Curve; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B 6 | 2001 |
[L-Methionine demercapto-deaminase; a new enzyme requiring pyridoxal-phosphate].
Topics: Enzymes; Methionine; Phosphates; Pyridoxal Phosphate | 1953 |
SUCCINIC ESTER AND AMIDE OF HOMOSERINE: SOME SPONTANEOUS AND ENZYMATIC REACTIONS.
Topics: Amides; Amino Acids; Cysteine; Escherichia coli; Homoserine; Methionine; Pyridoxal Phosphate; Research; Salmonella; Serine; Succinates | 1964 |
ORGAN AND INTRACELLULAR LOCATION OF THE METHIONINE METHYL GROUP SYNTHESIZING SYSTEM OF THE RAT.
Topics: Adenosine Triphosphate; Brain; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Glucose; Homocysteine; Kidney; Leuconostoc; Liver; Magnesium; Methionine; Muscles; NAD; Pectoralis Muscles; Proteins; Pyridoxal Phosphate; Rats; Research; Serine; Spectrophotometry | 1964 |
EFFECT OF PYRIDOXINE DEFICIENCY ON NUCLEIC ACID METABOLISM IN THE RAT.
Topics: Adenine; DNA; Formates; Liver; Metabolism; Methionine; Nucleic Acids; Nucleosides; Pyridoxal Phosphate; Rats; Research; RNA; Serine; Spleen; Thymidine; Transferases; Vitamin B 6 Deficiency | 1965 |
Influence of pyridoxine, pyridoxal phosphate, deoxypyridoxine, and 2,4-dinitrophenol on methionine absoption.
Topics: 2,4-Dinitrophenol; Coenzymes; Dinitrophenols; Gastrointestinal Tract; Humans; Methionine; Nitrophenols; Pyridoxal Phosphate; Pyridoxine; Vitamin B 6 | 1960 |
The pyridoxal phosphate-dependent oxidative decarboxylation of methionine by peroxidase. II. Identification of 3-methylthiopropionamide as a product of the reaction.
Topics: Amides; Coenzymes; Coloring Agents; Decarboxylation; Methionine; Oxidation-Reduction; Oxidoreductases; Peroxidase; Peroxidases; Propionates; Pyridoxal Phosphate | 1962 |
The pyridoxal phosphate-dependent oxidative decarboxylation of methionine by peroxidase. I. Characteristics and properties of the reaction.
Topics: Coenzymes; Coloring Agents; Decarboxylation; Methionine; Oxidation-Reduction; Oxidoreductases; Peroxidase; Peroxidases; Pyridoxal Phosphate | 1962 |
In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.
Topics: Animals; Antibodies; Antibody Specificity; Carbon-Sulfur Lyases; Chemistry, Pharmaceutical; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Fluorescamine; Half-Life; Methionine; Mice; Mice, Nude; Polyethylene Glycols; Pyridoxal Phosphate; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinimides | 2003 |
Plasma taurine and cysteine levels following an oral methionine load: relationship with coronary heart disease.
Topics: Adult; Case-Control Studies; Coronary Disease; Cysteine; Europe; Fasting; Humans; India; Male; Methionine; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Taurine | 2004 |
Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Female; Folic Acid; Germany; Homocysteine; Humans; Life Style; Linear Models; Longitudinal Studies; Male; Methionine; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Sex Characteristics; Smoking; Tea; Vitamin B 12 | 2004 |
Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Conserved Sequence; Crystallography, X-Ray; DNA Primers; Escherichia coli; Escherichia coli Proteins; Kinetics; Methionine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Sensitivity and Specificity; Sequence Alignment; Sequence Homology, Amino Acid; Transaminases | 2004 |
Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and men.
Topics: Adult; Carbon Isotopes; Deuterium; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pyridoxal Phosphate; Serine; Vitamin B 6 | 2005 |
Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Asparagine; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Cytosol; Databases, Protein; Glutamine; Kinetics; Ligands; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Serine; Serine O-Acetyltransferase; Threonine | 2005 |
Moderate hyperhomocysteinemia and early-onset central retinal vein occlusion.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxal Phosphate; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2006 |
Short communication: empirical and mechanistic evidence for the role of pyridoxal-5'-phosphate in the generation of methanethiol from methionine.
Topics: Cheese; Disulfides; Gas Chromatography-Mass Spectrometry; Methionine; Pyridoxal Phosphate; Sulfhydryl Compounds; Sulfides; Sulfur Compounds; Vitamin B 6 | 2006 |
Isolation of a homocysteine gamma-lyase-producing bacterium and study of its enzyme production conditions.
Topics: Bacteriological Techniques; Biomass; Bioreactors; Carbon; Enzyme Stability; Homocysteine; Hydrogen-Ion Concentration; Lyases; Methionine; Nitrogen; Pyridoxal Phosphate; Serratia; Soil Microbiology; Stimulation, Chemical | 2008 |
Taurine supplementation improves the utilization of sulfur-containing amino acids in rats continually administrated alcohol.
Topics: Alcohol Drinking; Animals; Cysteine; Ethanol; Methionine; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine | 2009 |
The reliability of methionine challenge test is not affected by a deficiency in pyridoxal phosphate, folic acid, or cobalamin.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Methionine; Pregnancy; Pyridoxal Phosphate; Reproducibility of Results; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2011 |
A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition.
Topics: Adult; Aged; Alcohol Drinking; Body Mass Index; Case-Control Studies; Cotinine; Diabetes Complications; DNA-Binding Proteins; Europe; Female; Flavin Mononucleotide; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Prospective Studies; Pyridoxal Phosphate; Riboflavin; Risk Factors; Sex Factors; Smoking; Transcription Factors; Vitamin B 12; Vitamin B Complex | 2011 |
B-vitamin deficiency is protective against DSS-induced colitis in mice.
Topics: Analysis of Variance; Animals; Body Weight; Colitis; Dextran Sulfate; Gene Expression; Glutathione; Homocysteine; Inflammation; Interleukin-10; Kaplan-Meier Estimate; Male; Metabolomics; Methionine; Methylmalonic Acid; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Peroxidase; Pyridoxal Phosphate; S-Adenosylhomocysteine; Severity of Illness Index; Tumor Necrosis Factor-alpha; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2011 |
A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes.
Topics: Biosynthetic Pathways; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Catalytic Domain; Crystallography, X-Ray; Cystathionine gamma-Lyase; Cysteine; Methionine; Protein Conformation; Protein Folding; Pyridoxal Phosphate; Structural Homology, Protein; Sulfur; Wolinella | 2011 |
Assembly of the eukaryotic PLP-synthase complex from Plasmodium and activation of the Pdx1 enzyme.
Topics: Ammonia; Catalytic Domain; Crystallography; Enzyme Activation; Glutaminase; Methionine; Models, Molecular; Multiprotein Complexes; Plasmodium falciparum; Protein Conformation; Pyridoxal Phosphate | 2012 |
Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Arabidopsis; Arabidopsis Proteins; Ethylenes; Indoleacetic Acids; Indoles; Methionine; Molecular Sequence Data; Mutation; Pyridoxal Phosphate; Transaminases; Tryptophan | 2013 |
Identification and characterization of a methionine γ-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora.
Topics: Amino Acid Sequence; Aminoglycosides; Ammonium Compounds; Bacterial Proteins; Butyrates; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Catalytic Domain; Coenzymes; Crystallography, X-Ray; Enediynes; Gene Expression; Holoenzymes; Methionine; Micromonospora; Models, Molecular; Molecular Sequence Data; Multigene Family; Pyridoxal Phosphate; Sequence Alignment; Sequence Homology, Amino Acid; Sulfhydryl Compounds | 2015 |
Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Arginine; Biomarkers; Dietary Supplements; Female; Healthy Volunteers; Humans; Kynurenic Acid; Kynurenine; Life Style; Male; Methionine; ortho-Aminobenzoates; Pyridoxal Phosphate; Sex Factors; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Xanthurenates; Young Adult | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
Structure of methionine γ-lyase from Clostridium sporogenes.
Topics: Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Clostridium; Crystallization; Crystallography, X-Ray; Hydrogen Bonding; Kinetics; Methionine; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Pyridoxal Phosphate | 2016 |
Gene cloning, recombinant expression, purification and characterization of l-methionine decarboxylase from Streptomyces sp. 590.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Carbon Dioxide; Carboxy-Lyases; Cell Line; Cell Line, Tumor; Cell Proliferation; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Humans; Hydrogen-Ion Concentration; Kinetics; Methionine; Molecular Weight; Phylogeny; Propylamines; Protein Multimerization; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Streptomyces; Substrate Specificity; Temperature | 2017 |
Structural Snapshots of an Engineered Cystathionine-γ-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Topics: Amino Acid Substitution; Arginine; Biocatalysis; Carbon-Sulfur Lyases; Catalytic Domain; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Enzyme Stability; Humans; Hydrogen Bonding; Hydrolysis; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Protein Engineering; Pyridoxal Phosphate; Recombinant Proteins; Selenomethionine; Substrate Specificity | 2017 |
Methionine tumor starvation by erythrocyte-encapsulated methionine gamma-lyase activity controlled with per os vitamin B6.
Topics: Animals; Antineoplastic Agents; Carbon-Sulfur Lyases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Delivery Systems; Erythrocytes; Humans; Male; Methionine; Mice, Nude; Neoplasms; Pyridoxal Phosphate; Pyridoxine; Recombinant Proteins; Tumor Burden | 2017 |
X-Ray snapshots of a pyridoxal enzyme: a catalytic mechanism involving concerted [1,5]-hydrogen sigmatropy in methionine γ-lyase.
Topics: Carbon-Sulfur Lyases; Crystallography, X-Ray; Entamoeba histolytica; Methionine; Models, Molecular; Protein Conformation; Pyridoxal Phosphate | 2017 |
Methionine coordinates a hierarchically organized anabolic program enabling proliferation.
Topics: Basic-Leucine Zipper Transcription Factors; Cell Proliferation; Gene Expression Regulation, Fungal; Glutamate Dehydrogenase; Glutamic Acid; Glutamine; Metabolism; Methionine; Nucleotides; Pentose Phosphate Pathway; Pyridoxal Phosphate; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2018 |
Identification of O-acetylhomoserine sulfhydrylase, a putative enzyme responsible for methionine biosynthesis in Clostridioides difficile: Gene cloning and biochemical characterizations.
Topics: Alkynes; Amino Acid Sequence; Carbon-Oxygen Lyases; Cloning, Molecular; Clostridioides difficile; Genome, Bacterial; Glycine; Methionine; Pyridoxal Phosphate; Sequence Homology; Substrate Specificity; Sulfhydryl Compounds | 2019 |
Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis.
Topics: Alkylation; Anti-Bacterial Agents; Biochemical Phenomena; Methionine; Nucleosides; Phosphates; Phosphorylation; Pyridoxal Phosphate; Recombinant Proteins; S-Adenosylmethionine | 2020 |
Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Topics: Acetylgalactosamine; Adult; Arginine; Cystathionine beta-Synthase; Female; Folic Acid; Heme; Homeostasis; Homocysteine; Homocystinuria; Humans; Hydroxymethylbilane Synthase; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Porphyria, Acute Intermittent; Pyridoxal Phosphate; Pyrrolidines; Young Adult | 2021 |
Characterization and application of l-methionine γ-lyase Q349S mutant enzyme with an enhanced activity toward l-homocysteine.
Topics: Carbon-Sulfur Lyases; Homocysteine; Methionine; Pseudomonas putida; Pyridoxal Phosphate | 2022 |
Analyses of pre-steady-state kinetics and isotope effects of the γ-elimination reaction catalyzed by Citrobacter freundii methionine γ-lyase.
Topics: Amino Acids; Carbon-Sulfur Lyases; Catalysis; Citrobacter freundii; Deuterium; Imines; Kinetics; Methionine; Nitriles; Phosphates; Protons; Pyridoxal Phosphate | 2022 |
Topics: Animals; Cryoelectron Microscopy; Cystathionine beta-Synthase; Cysteine; Methionine; Mice; Mycobacterium tuberculosis; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylmethionine; Sulfur | 2022 |
Proteomic, Transcriptomic, Mutational, and Functional Assays Reveal the Involvement of Both THF and PLP Sites at the GmSHMT08 in Resistance to Soybean Cyst Nematode.
Topics: Animals; Carbon; Cysts; Glycine; Glycine Hydroxymethyltransferase; Glycine max; Glyoxylates; Heme; Methionine; Nematoda; Plant Diseases; Proteomics; Purines; Pyridoxal Phosphate; Serine; Tetrahydrofolates; Transcriptome | 2022 |
O-Acetylhomoserine Sulfhydrylase from Clostridioides difficile: Role of Tyrosine Residues in the Active Site.
Topics: Catalytic Domain; Clostridioides; Clostridioides difficile; Cysteine Synthase; Kinetics; Methionine; Pyridoxal Phosphate; Tyrosine | 2023 |
PLP-Dependent Enzyme Methionine γ-Lyase: Insights into the Michaelis Complex from Molecular Dynamics and Free Energy Simulations.
Topics: Ligands; Methionine; Molecular Dynamics Simulation; Pyridoxal Phosphate; Racemethionine; Schiff Bases | 2023 |