methionine has been researched along with lovastatin in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (14.81) | 18.7374 |
| 1990's | 13 (48.15) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Casey, WM; Keesler, GA; Parks, LW | 1 |
| Bereziat, G; Chambaz, J; Janvier, B; Loriette, C; Mangeney, M; Pepin, D; Ribeiro, A; Thomas, G | 1 |
| Beck, L; Leonard, S; Sinensky, M | 1 |
| Fliesler, SJ; Keller, RK | 1 |
| Buddecke, E; Filipovic, I | 1 |
| Don, HS; Shiao, MS | 1 |
| Knight, BL; Patel, DD; Soutar, AK | 1 |
| Jeng, I; Klemm, N; Proctor, B | 1 |
| Hohl, RJ; Lewis, K | 1 |
| D'Andrea, P; Grossman, JS; Latter, GI; Patterson, SD | 1 |
| Hamilton, AD; McGuire, TF; Qian, Y; Sebti, SM; Vogt, A | 2 |
| Hamilton, AD; Qian, Y; Sebti, SM; Sun, J; Vogt, A | 1 |
| Blaskovich, MA; Davies, P; Hamilton, AD; Johnson, BA; Pitt, B; Qian, Y; Sebti, SM; Stark, WW; Vasudevan, A | 1 |
| Bifulco, M; Di Matola, T; Fenzi, G; Laezza, C; Rossi, G; Vitale, M | 1 |
| Dumont, JE; Fusco, A; Golstein, J; Kimura, T | 1 |
| Bailey, R; Hamilton, AD; Harlan, JM; Kovach, NL; Liu, L; Moesner, P; Sebti, SM | 1 |
| Aklilu, F; Gladu, J; Goltzman, D; Rabbani, SA | 1 |
| Dimitroulakos, J; Minden, MD; Penn, LZ; Tan, MM; Wong, WW; Xia, Z | 1 |
| Bannerman, DD; Hamilton, AD; Harlan, JM; Li, X; Liu, L; Sebti, SM; Tupper, JC; Winn, RK | 1 |
| Hohl, RJ; Holstein, SA; Wohlford-Lenane, CL | 1 |
| Efuet, ET; Keyomarsi, K | 1 |
| Broers, JL; Hennekam, RC; Kamps, M; Kuijpers, HJ; Marcelis, CL; Merckx, D; Ramaekers, FC; Smeets, HJ; Steijlen, PM; van den Wijngaard, A; van Steensel, MA; Verstraeten, VL; Zinn-Justin, S | 1 |
| Beck, JF; Bumbul, B; Sonnemann, J | 1 |
| Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I | 1 |
1 review(s) available for methionine and lovastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
26 other study(ies) available for methionine and lovastatin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Stimulation by heme of steryl ester synthase and aerobic sterol exclusion in the yeast Saccharomyces cerevisiae.
Topics: Acyltransferases; Aerobiosis; Aminolevulinic Acid; Esterification; Fatty Acids, Unsaturated; Heme; Lovastatin; Methionine; Saccharomyces cerevisiae; Sterol O-Acyltransferase; Sterols | 1992 |
Effect of simvastatin on the synthesis and secretion of lipoproteins in relation to the metabolism of cholesterol in cultured hepatocytes.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cholesterol; Cholesterol Esters; Fatty Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins; Liver; Lovastatin; Male; Methionine; Rats; Rats, Inbred Strains; Simvastatin; Triglycerides | 1991 |
Inhibition of isoprenoid biosynthesis and the post-translational modification of pro-p21.
Topics: Animals; Cell Line; Cholesterol; Genes, ras; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Methionine; Mevalonic Acid; Oncogene Protein p21(ras); Protein Precursors; Protein Processing, Post-Translational; Transfection | 1990 |
Incorporation of squalene into rod outer segments.
Topics: Acetates; Animals; Cell Membrane; Cysteine; Lovastatin; Membrane Lipids; Membrane Proteins; Methionine; Photoreceptor Cells; Puromycin; Rana pipiens; Retina; Rod Cell Outer Segment; Squalene; Sulfur Radioisotopes; Tritium | 1990 |
Calmodulin antagonists stimulate LDL receptor synthesis in human skin fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Acetates; Acetic Acid; Androstenes; Calcium Chloride; Calmodulin; Cholera Toxin; Cholesterol; Cyclic AMP; Fibroblasts; Humans; Hydroxycholesterols; Lovastatin; Methionine; Mevalonic Acid; Molecular Weight; Naphthalenes; p-Methoxy-N-methylphenethylamine; Receptors, LDL; Skin; Sulfonamides; Trifluoperazine | 1986 |
Biosynthesis of mevinolin, a hypocholesterolemic fungal metabolite, in Aspergillus terreus.
Topics: Anticholesteremic Agents; Aspergillus; Butyrates; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Lovastatin; Methionine; Methylation; S-Adenosylmethionine; T-2 Toxin; Tritium | 1987 |
Regulation of synthesis and cell content of the low-density-lipoprotein receptor protein in cultured fibroblasts from normal and familial hypercholesterolaemic subjects.
Topics: Acetates; Cell Membrane; Cells, Cultured; Cholesterol; Fibroblasts; Humans; Hyperlipoproteinemia Type II; Immunochemistry; Lipoproteins; Lovastatin; Methionine; Naphthalenes; Radioimmunoassay; Receptors, LDL | 1987 |
Insensitivity of ubiquinone biosynthesis in glioblastoma cells to an epileptogenic drug, U18666A.
Topics: Androstenes; Animals; Anticholesteremic Agents; Cell Line; Glioma; Hydroxybenzoates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Methionine; Mevalonic Acid; Naphthalenes; Parabens; Rats; Tyrosine; Ubiquinone | 1984 |
Differential effects of monoterpenes and lovastatin on RAS processing.
Topics: Cells, Cultured; Cyclohexenes; Humans; Limonene; Lovastatin; Methionine; Monoterpenes; ras Proteins; Terpenes | 1995 |
Reduced numatrin/B23/nucleophosmin labeling in apoptotic Jurkat T-lymphoblasts.
Topics: Apoptosis; Cells, Cultured; Cysteine; Egtazic Acid; Electrophoresis, Gel, Two-Dimensional; Humans; Lovastatin; Methionine; Nuclear Proteins; Nucleophosmin; T-Lymphocytes | 1995 |
Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation.
Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Diterpenes; Enzyme Inhibitors; Farnesol; Farnesyltranstransferase; Kinetics; Lovastatin; Methionine; Mice; Phosphorylation; Phosphotyrosine; Protein Prenylation; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Structure-Activity Relationship; Transfection; Transferases | 1996 |
Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts.
Topics: Actins; Alkyl and Aryl Transferases; Animals; Benzamides; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cytoskeleton; Diterpenes; DNA; Enzyme Inhibitors; Farnesol; Fibroblasts; G1 Phase; Genes, ras; GTP-Binding Proteins; Lovastatin; Methionine; Mevalonic Acid; Mice; Protein Prenylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; rap GTP-Binding Proteins; ras Proteins; Resting Phase, Cell Cycle; S Phase; Transferases | 1996 |
The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner.
Topics: Alkyl and Aryl Transferases; Benzamides; Breast Neoplasms; Cell Cycle; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Female; Fibrosarcoma; G1 Phase; Head and Neck Neoplasms; Humans; Lovastatin; Methionine; Oligopeptides; Pancreatic Neoplasms; Protein Prenylation; Resting Phase, Cell Cycle; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 1997 |
Inhibiting geranylgeranylation blocks growth and promotes apoptosis in pulmonary vascular smooth muscle cells.
Topics: Alkyl and Aryl Transferases; Animals; Apoptosis; Benzamides; Cell Division; Cells, Cultured; Enzyme Inhibitors; Farnesyltranstransferase; Flow Cytometry; GTP-Binding Proteins; Kinetics; Lovastatin; Methionine; Microcirculation; Muscle, Smooth, Vascular; Protein Prenylation; Pulmonary Artery; rap GTP-Binding Proteins; ras Proteins; Rats; Transcription Factors | 1998 |
Prenyltransferase inhibitors induce apoptosis in proliferating thyroid cells through a p53-independent CrmA-sensitive, and caspase-3-like protease-dependent mechanism.
Topics: Apoptosis; Benzamides; Caspases; Cell Division; Cell Line; Cysteine Proteinase Inhibitors; Dimethylallyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Methionine; Serpins; Thyroid Gland; Tumor Suppressor Protein p53; Viral Proteins | 1999 |
Insulin and TSH promote growth in size of PC Cl3 rat thyroid cells, possibly via a pathway different from DNA synthesis: comparison with FRTL-5 cells.
Topics: Animals; Cell Division; Cell Line, Transformed; Cell Size; DNA; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Lovastatin; Methionine; Protein Biosynthesis; Rats; Sulfur Radioisotopes; Thyrotropin | 1999 |
Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s).
Topics: Benzamides; Cell Adhesion; Diterpenes; Fibronectins; Humans; Integrins; Jurkat Cells; Leukocytes; Lovastatin; Methionine; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Tetradecanoylphorbol Acetate; U937 Cells | 1999 |
Role of mitogen-activated protein kinases in the induction of parathyroid hormone-related peptide.
Topics: Animals; Antineoplastic Agents; Calcium; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Lovastatin; Male; Methionine; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Neoplasms, Experimental; Parathyroid Hormone-Related Protein; Proteins; Proto-Oncogene Proteins c-raf; rac1 GTP-Binding Protein; ras Proteins; Rats; Rats, Inbred F344; RNA, Messenger; Signal Transduction; Ultraviolet Rays | 2000 |
Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells.
Topics: Acute Disease; Apoptosis; Benzamides; Deoxyuracil Nucleotides; Fluorescein-5-isothiocyanate; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lovastatin; Methionine; Mevalonic Acid; Polyisoprenyl Phosphates; Protein Prenylation; Sesquiterpenes; Tumor Cells, Cultured | 2001 |
Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells.
Topics: Apoptosis; Benzamides; Caspase 3; Caspases; Cell Death; Cells, Cultured; Diterpenes; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Lovastatin; Methionine; Polyisoprenyl Phosphates; Protein Prenylation; Protein Serine-Threonine Kinases; rho-Associated Kinases; rhoA GTP-Binding Protein; Umbilical Veins | 2002 |
Isoprenoids influence expression of Ras and Ras-related proteins.
Topics: Antineoplastic Agents; Blotting, Northern; Blotting, Western; Cycloheximide; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Humans; K562 Cells; Leucine; Lovastatin; Methionine; Mevalonic Acid; Polyisoprenyl Phosphates; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; rap1 GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Time Factors; Transcription, Genetic; Up-Regulation | 2002 |
Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome.
Topics: Antineoplastic Agents; Benzamides; Breast Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; G1 Phase; Humans; Lactic Acid; Lovastatin; Methionine; Proteasome Endopeptidase Complex; Protein Prenylation; rap1 GTP-Binding Proteins; ras Proteins; Tumor Cells, Cultured; Up-Regulation | 2006 |
Compound heterozygosity for mutations in LMNA causes a progeria syndrome without prelamin A accumulation.
Topics: Adult; Bone and Bones; Cell Survival; Cells, Cultured; Child, Preschool; Female; Fibroblasts; Heterozygote; Humans; Imaging, Three-Dimensional; Immunohistochemistry; Lamin Type A; Lovastatin; Male; Methionine; Models, Molecular; Mutation; Nuclear Proteins; Progeria; Protein Precursors; Protein Prenylation; Radiography | 2006 |
Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro.
Topics: Antineoplastic Agents; Benzamides; Cell Death; Cell Line, Tumor; Diphosphonates; Drug Screening Assays, Antitumor; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Imidazoles; Lovastatin; Male; Methionine; Mitochondria; Prostatic Neoplasms; Vorinostat; Zoledronic Acid | 2007 |
Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis.
Topics: Animals; Benzamides; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cholesterol; Encephalomyelitis, Autoimmune, Experimental; Female; Hydroxymethylglutaryl CoA Reductases; Inflammation; Lovastatin; Methionine; Mevalonic Acid; Myelin Sheath; Nerve Growth Factors; Neuroglia; Oligodendroglia; Polyisoprenyl Phosphates; ras Proteins; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Spinal Cord; Wound Healing | 2008 |