methionine has been researched along with levoleucovorin in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (61.76) | 18.7374 |
| 1990's | 4 (11.76) | 18.2507 |
| 2000's | 3 (8.82) | 29.6817 |
| 2010's | 5 (14.71) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Benesh, FC; Carl, GF | 1 |
| Lejeune, J | 1 |
| Cook, RJ; Horne, DW; Wagner, C | 1 |
| Karasawa, M; Maekawa, T; Omine, M; Yatabe, H | 1 |
| Ongari, R; Piva, M | 1 |
| Clark, JM; Klein, WH; Lazar, JM; Lundquist, RE | 1 |
| Monnens, LA; Schretlen, ED; Sengers, RC; Trijbels, JM; van der Zee, SP; Vrenken, JA | 1 |
| Bayley, ST; White, BN | 1 |
| Clark, BF; Ebel, JP; Giegé, R | 1 |
| Ishizuka, S; Kakutani, T; Kawakami, M | 1 |
| Rabinowitz, JC; Samuel, CE | 1 |
| Murray, CL; Rabinowitz, JC; Samuel, CE | 1 |
| Bosch, L; Bosselaar, A; Hoogendam, BW; v Ravenswaay Claasen, JC; Voorma, HO | 1 |
| Gold, LM; Schweiger, M | 1 |
| Schulman, LH | 1 |
| Wickstrom, E | 1 |
| Chiossi, FM | 1 |
| Fujii, K; Huennekens, FM; Nagasaki, T | 1 |
| Cooper, BA; Harpey, JP; Lafourcade, J; Le Moël, G; Rosenblatt, DS; Roy, C | 1 |
| Baden, JM; Fujinaga, M | 1 |
| Alonso, E; Martín-Rodríguez, JC; Pérez-Miguelsanz, J; Puerta, J; Ubeda, N; Varela-Moreiras, G | 1 |
| Clelland, J; Hann, I; Surtees, R | 1 |
| Broët, P; Delmas-Marsalet, B; Falissard, B; Goldschmidt, E; Hoffman, RM; Luccioni, C; Machover, D; Metzger, G; Orrico, M; Schilf, A; Tan, Y; Tonetti, C; Zittoun, J | 1 |
| Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P | 1 |
| MARCHETTI, M; MORUZZI, G; VIVIANI, R | 2 |
| AL-WATTAR, J; GERSHBEIN, LL; MILLER, A | 1 |
| Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA | 1 |
| Abrial, C; Buc, E; Chollet, P; Durando, X; Farges, MC; Gillet, B; Petorin-Lesens, C; Pezet, D; Thivat, E; Vasson, MP | 1 |
| Arning, E; Bottiglieri, T; Caudill, MA; Christensen, KE; Deng, L; Greene, ND; Jerome-Majewska, L; Krupenko, NI; Leung, KY; MacKenzie, RE; Malysheva, OV; Rozen, R | 1 |
| Benoist, JF; Cornec-Le Gall, E; De Parscau, L; Delmas, Y; Doucet, L; Fremeaux-Bacchi, V; Le Meur, Y; Ogier, H | 1 |
| Daignan-Fornier, B; Hürlimann, HC; Pinson, B; Saint-Marc, C | 1 |
| Blom, HJ; Castro, R; Esse, R; Koolwijk, P; Tavares de Almeida, I; Teerlink, T | 1 |
| Aoki, Y; Han, Q; Hoffman, RM; Hozumi, C; Kubota, Y; Masaki, N; Tsunoda, T; Yamamoto, J | 1 |
2 review(s) available for methionine and levoleucovorin
| Article | Year |
|---|---|
Methyl biogenesis.
Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates | 1978 |
[The pathogenesis of mental retardation in trisomy 21].
Topics: Amyloid beta-Protein Precursor; Biopterins; Brain; Carbonic Acid; Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Guanosine; Humans; Leucovorin; Mercaptopurine; Methionine; Neurons; Phosphofructokinase-1; Purines; Pyrimidines; S100 Proteins; Superoxide Dismutase; Thyroid Gland; Thyroxine | 1991 |
2 trial(s) available for methionine and levoleucovorin
| Article | Year |
|---|---|
Demyelination and single-carbon transfer pathway metabolites during the treatment of acute lymphoblastic leukemia: CSF studies.
Topics: Antidotes; Antimetabolites, Antineoplastic; Central Nervous System; Child; Child, Preschool; Combined Modality Therapy; Demyelinating Diseases; Drug Interactions; Humans; Infant; Leucovorin; Methionine; Methotrexate; Myelin Basic Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; S-Adenosylmethionine; Tetrahydrofolates | 1998 |
Dietary methionine restriction with FOLFOX regimen as first line therapy of metastatic colorectal cancer: a feasibility study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diet; Disease Progression; Feasibility Studies; Female; Fluorouracil; Humans; Leucovorin; Male; Methionine; Middle Aged; Models, Statistical; Monitoring, Physiologic; Neoplasm Metastasis; Organoplatinum Compounds; Treatment Outcome | 2010 |
30 other study(ies) available for methionine and levoleucovorin
| Article | Year |
|---|---|
Effect of dietary methyl group deficiency on folate metabolism in rats.
Topics: Amino Acids; Animals; Choline Deficiency; Chromatography, High Pressure Liquid; Diet; Folic Acid; Leucovorin; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; Tetrahydrofolates | 1989 |
Growth and DNA synthesis of folate- and methionine-depleted L1210 mouse leukemia cells in culture.
Topics: Animals; Cell Division; Cells, Cultured; Deoxyuridine; DNA; Folic Acid; Leucovorin; Leukemia L1210; Methionine; Mice | 1987 |
[Considerations on the clinical use of a new association of drugs in the treatment of hepatopathies].
Topics: Adolescent; Adult; Aged; Humans; Leucovorin; Liver Diseases; Methionine; Middle Aged; Niacinamide; Nucleosides; Vitamin B 12 | 1968 |
Translation of satellite tobacco necrosis virus ribonucleic acid. II. Initiation of in vitro translation in procaryotic and eucaryotic systems.
Topics: Alanine; Amino Acids; Bacterial Proteins; Carbon Isotopes; Cell Nucleus; Cell-Free System; Escherichia coli; Formates; Leucovorin; Methionine; NAD; Nicotiana; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Peptide Hydrolases; Plant Proteins; Plant Viruses; Plants; Plants, Toxic; RNA, Messenger; RNA, Transfer; RNA, Viral; Trimethoprim; Triticum; Tritium | 1972 |
A patient with nonketotic hyperglycinemia: biochemical findings and therapeutic approaches.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Benzoates; Biopsy; Carbon Radioisotopes; Child, Preschool; Choline; Diet Therapy; Electroencephalography; Female; Folic Acid; Glycine; Humans; Infant; Infant, Newborn; Leucovorin; Liver; Methionine; Pyridoxine; Salicylates; Tetrahydrofolates | 1974 |
Methionine transfer RNAs from the extreme halophile, Halobacterium cutirubrum.
Topics: Acyltransferases; Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Electrophoresis, Paper; Escherichia coli; Formates; Halobacterium; Leucovorin; Liver; Methionine; RNA, Bacterial; RNA, Transfer; Sulfur Isotopes; Tetrahydrofolates | 1972 |
Formylation of mischarged E. coli tRNA Met f .
Topics: Amino Acyl-tRNA Synthetases; Autoradiography; Carbon Isotopes; Electrophoresis, Paper; Escherichia coli; Formates; Hydrolysis; Kinetics; Leucovorin; Methionine; Phenylalanine; RNA, Bacterial; RNA, Transfer; Valine; Yeasts | 1973 |
Methionine transfer RNA from insect tissue.
Topics: Amino Acyl-tRNA Synthetases; Bombyx; Carbon Radioisotopes; Chromatography, Ion Exchange; Escherichia coli; Formates; Leucovorin; Methionine; RNA, Transfer | 1974 |
Effect of formylation on the chromatographic behavior of methionyl transfer ribonucleic acid.
Topics: Amino Acyl-tRNA Synthetases; Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Clostridium; Enterococcus faecalis; Formates; Isotope Labeling; Leucovorin; Ligases; Methionine; RNA, Transfer; Tetrahydrofolates; Transferases; Tritium | 1972 |
Methionine transfer ribonucleic acid from folate-sufficient and folate-deficient Streptococcus faecalis R.
Topics: Acylation; Amino Acids; Amino Acyl-tRNA Synthetases; Ammonia; Carbon Isotopes; Chromatography, DEAE-Cellulose; Culture Media; Electrophoresis, Paper; Enterococcus faecalis; Escherichia coli; Folic Acid; Formates; Hydrolysis; Kinetics; Leucovorin; Methionine; Pancreas; Ribonucleases; RNA, Transfer; Salmonella typhimurium; Sulfur Isotopes; Tritium | 1972 |
Chain initiation during polypeptide synthesis in cell-free bacterial systems programmed with plant viral messengers. II. The role of N-formylmethionine.
Topics: Amino Acids; Cell-Free System; Coliphages; Escherichia coli; Formates; Kinetics; Leucovorin; Magnesium; Methionine; Peptide Biosynthesis; Plant Viruses; RNA, Messenger; RNA, Transfer; RNA, Viral; Stimulation, Chemical; Sulfur Isotopes; Tobacco Mosaic Virus; Tritium | 1968 |
The initiation of T4 deoxyribonucleic acid-dependent beta-glucosyltransferase synthesis in vitro.
Topics: Coliphages; DNA, Viral; Escherichia coli; Folic Acid; Formates; Glucosyltransferases; Leucovorin; Magnesium; Methionine; Ribosomes; RNA, Bacterial; RNA, Transfer; Stimulation, Chemical; Templates, Genetic; Tritium; Viral Proteins | 1969 |
Structure and function of E. coli formylmethionyl tRNA. I. Effect of modification of pyrimidine residues on aminoacyl synthetase recognition.
Topics: Amino Acids; Carbon Isotopes; Chromatography, DEAE-Cellulose; Escherichia coli; Formates; Homocysteine; Leucovorin; Ligases; Methionine; Nucleotides; Radiation Effects; Ribonucleases; RNA, Transfer; Spectrum Analysis; Transferases; Ultraviolet Rays | 1970 |
Circular dichroism during deacylation of methionyl-tRNA met -f and formylmethionyl-tRNA met -f from E. coli.
Topics: Acylation; Adenosine Triphosphate; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Circular Dichroism; Drug Stability; Escherichia coli; Formates; Hydrogen-Ion Concentration; Kinetics; Leucovorin; Methionine; Models, Biological; Peptides; Ribosomes; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Sulfhydryl Reagents; Tetroses; Ultraviolet Rays | 1971 |
[A new hepatic therapeutic preparation. Its use in pediatrics].
Topics: Child; Child, Preschool; Evaluation Studies as Topic; Humans; Infant; Injections, Intravenous; Leucovorin; Liver; Liver Diseases; Methionine; Nucleosides; Vitamins | 1971 |
Vitamin B12-dependent replication of L1210 mouse leukemia cells. A model system for cobalamin-folate inter-relationships.
Topics: Animals; Cell Division; Folic Acid; Kinetics; Leucovorin; Leukemia L1210; Methionine; Mice; Structure-Activity Relationship; Vitamin B 12 | 1981 |
Homocystinuria caused by 5,10-methylenetetrahydrofolate reductase deficiency: a case in an infant responding to methionine, folinic acid, pyridoxine, and vitamin B12 therapy.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alcohol Oxidoreductases; Amino Acids; Drug Therapy, Combination; Female; Folic Acid; Homocystinuria; Humans; Infant; Leucovorin; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Pyridoxine; Skin; Tetrahydrofolates; Vitamin B 12 | 1981 |
Methionine prevents nitrous oxide-induced teratogenicity in rat embryos grown in culture.
Topics: Abnormalities, Drug-Induced; Animals; Culture Techniques; Embryo, Mammalian; Female; Leucovorin; Male; Methionine; Models, Biological; Nitrous Oxide; Phenylephrine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Situs Inversus | 1994 |
Valproate-induced developmental modifications maybe partially prevented by coadministration of folinic acid and S-adenosylmethionine.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Female; Fetus; Leucovorin; Liver; Methionine; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; S-Adenosylmethionine; Valproic Acid | 1996 |
Cytotoxic synergism of methioninase in combination with 5-fluorouracil and folinic acid.
Topics: Antimetabolites, Antineoplastic; Carbon-Sulfur Lyases; Cell Division; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Leucovorin; Methionine; Recombinant Proteins; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 2001 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12 | 2001 |
EFFECT OF OROTIC ACID ON THE SYNTHESIS OF CITROVORUM FACTOR AND OF METHIONINE IN LIVER OF THE CHICK.
Topics: Animals; Chickens; Corrinoids; Folic Acid; Leuconostoc; Leucovorin; Liver; Meat; Metabolism; Methionine; Orotic Acid; Pharmacology; Poultry; Proteins; Research; Vitamin B 12 | 1963 |
OROTIC ACID AND METABOLISM OF ONE CARBON UNIT: CONVERSION OF FOLIC ACID TO CITROVORUM FACTOR AND METHIONINE SYNTHESIS IN CHICK LIVER.
Topics: Animals; Carbon; Chickens; Folic Acid; Homocysteine; Leuconostoc; Leucovorin; Liver; Metabolism; Methionine; Orotic Acid; Poultry; Proteins; Research; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1963 |
EFFECT OF WATER-SOLUBLE VITAMINS ON RAT DIAPHRAGM CARBOHYDRATE METABOLISM.
Topics: 4-Aminobenzoic Acid; Ascorbic Acid; Carbohydrate Metabolism; Diaphragm; Folic Acid; Inositol; Leucovorin; Metabolism; Methionine; Muscles; Pantothenic Acid; Pharmacology; Pyridoxine; Rats; Research; Vitamins | 1964 |
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 2004 |
A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
Topics: Aminohydrolases; Animals; Cell Proliferation; Cells, Cultured; Choline; Congenital Abnormalities; Embryo Loss; Embryonic Development; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Gene Knock-In Techniques; Genetic Variation; Humans; Leucovorin; Leukocyte Count; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Models, Animal; Multienzyme Complexes; Multifunctional Enzymes; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Purines | 2013 |
Adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin C deficiency.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antibodies, Monoclonal, Humanized; Betaine; Biopsy; Carrier Proteins; Diagnosis, Differential; Drug Resistance; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Hypertension, Malignant; Immunologic Factors; Kidney; Kidney Function Tests; Leucovorin; Lipotropic Agents; Male; Methionine; Methylmalonic Acid; Mutation; Oxidoreductases; Recurrence; Renal Dialysis; Treatment Outcome; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Serine hydroxymethyltransferase: a key player connecting purine, folate and methionine metabolism in Saccharomyces cerevisiae.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aminoimidazole Carboxamide; Carbon-Nitrogen Ligases; Folic Acid; Gene Expression Regulation, Fungal; Glycine Hydroxymethyltransferase; Histidine; Leucovorin; Methionine; Mutation; Purines; Ribonucleotides; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tetrahydrofolates; Thymidine; Trans-Activators; Transcriptional Activation | 2015 |
Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells.
Topics: Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Leucovorin; Methionine; Methylation; Protein Processing, Post-Translational; S-Adenosylhomocysteine | 2018 |
Stage IV Pancreatic Cancer Patient Treated With FOLFIRINOX Combined With Oral Methioninase: A Highly-Rare Case With Long-term Stable Disease.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carbon-Sulfur Lyases; Disease Models, Animal; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Methionine; Mice; Mice, Nude; Oxaliplatin; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2022 |