Page last updated: 2024-08-17

methionine and levoleucovorin

methionine has been researched along with levoleucovorin in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199021 (61.76)18.7374
1990's4 (11.76)18.2507
2000's3 (8.82)29.6817
2010's5 (14.71)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Benesh, FC; Carl, GF1
Lejeune, J1
Cook, RJ; Horne, DW; Wagner, C1
Karasawa, M; Maekawa, T; Omine, M; Yatabe, H1
Ongari, R; Piva, M1
Clark, JM; Klein, WH; Lazar, JM; Lundquist, RE1
Monnens, LA; Schretlen, ED; Sengers, RC; Trijbels, JM; van der Zee, SP; Vrenken, JA1
Bayley, ST; White, BN1
Clark, BF; Ebel, JP; Giegé, R1
Ishizuka, S; Kakutani, T; Kawakami, M1
Rabinowitz, JC; Samuel, CE1
Murray, CL; Rabinowitz, JC; Samuel, CE1
Bosch, L; Bosselaar, A; Hoogendam, BW; v Ravenswaay Claasen, JC; Voorma, HO1
Gold, LM; Schweiger, M1
Schulman, LH1
Wickstrom, E1
Chiossi, FM1
Fujii, K; Huennekens, FM; Nagasaki, T1
Cooper, BA; Harpey, JP; Lafourcade, J; Le Moël, G; Rosenblatt, DS; Roy, C1
Baden, JM; Fujinaga, M1
Alonso, E; Martín-Rodríguez, JC; Pérez-Miguelsanz, J; Puerta, J; Ubeda, N; Varela-Moreiras, G1
Clelland, J; Hann, I; Surtees, R1
Broët, P; Delmas-Marsalet, B; Falissard, B; Goldschmidt, E; Hoffman, RM; Luccioni, C; Machover, D; Metzger, G; Orrico, M; Schilf, A; Tan, Y; Tonetti, C; Zittoun, J1
Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P1
MARCHETTI, M; MORUZZI, G; VIVIANI, R2
AL-WATTAR, J; GERSHBEIN, LL; MILLER, A1
Cutler, P; Gaylor, DW; James, SJ; Janak, L; Jernigan, S; Melnyk, S; Neubrander, JA1
Abrial, C; Buc, E; Chollet, P; Durando, X; Farges, MC; Gillet, B; Petorin-Lesens, C; Pezet, D; Thivat, E; Vasson, MP1
Arning, E; Bottiglieri, T; Caudill, MA; Christensen, KE; Deng, L; Greene, ND; Jerome-Majewska, L; Krupenko, NI; Leung, KY; MacKenzie, RE; Malysheva, OV; Rozen, R1
Benoist, JF; Cornec-Le Gall, E; De Parscau, L; Delmas, Y; Doucet, L; Fremeaux-Bacchi, V; Le Meur, Y; Ogier, H1
Daignan-Fornier, B; Hürlimann, HC; Pinson, B; Saint-Marc, C1
Blom, HJ; Castro, R; Esse, R; Koolwijk, P; Tavares de Almeida, I; Teerlink, T1
Aoki, Y; Han, Q; Hoffman, RM; Hozumi, C; Kubota, Y; Masaki, N; Tsunoda, T; Yamamoto, J1

Reviews

2 review(s) available for methionine and levoleucovorin

ArticleYear
Methyl biogenesis.
    Biological psychiatry, 1978, Volume: 13, Issue:4

    Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates

1978
[The pathogenesis of mental retardation in trisomy 21].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1991, Volume: 139, Issue:10

    Topics: Amyloid beta-Protein Precursor; Biopterins; Brain; Carbonic Acid; Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Guanosine; Humans; Leucovorin; Mercaptopurine; Methionine; Neurons; Phosphofructokinase-1; Purines; Pyrimidines; S100 Proteins; Superoxide Dismutase; Thyroid Gland; Thyroxine

1991

Trials

2 trial(s) available for methionine and levoleucovorin

ArticleYear
Demyelination and single-carbon transfer pathway metabolites during the treatment of acute lymphoblastic leukemia: CSF studies.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:4

    Topics: Antidotes; Antimetabolites, Antineoplastic; Central Nervous System; Child; Child, Preschool; Combined Modality Therapy; Demyelinating Diseases; Drug Interactions; Humans; Infant; Leucovorin; Methionine; Methotrexate; Myelin Basic Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; S-Adenosylmethionine; Tetrahydrofolates

1998
Dietary methionine restriction with FOLFOX regimen as first line therapy of metastatic colorectal cancer: a feasibility study.
    Oncology, 2010, Volume: 78, Issue:3-4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diet; Disease Progression; Feasibility Studies; Female; Fluorouracil; Humans; Leucovorin; Male; Methionine; Middle Aged; Models, Statistical; Monitoring, Physiologic; Neoplasm Metastasis; Organoplatinum Compounds; Treatment Outcome

2010

Other Studies

30 other study(ies) available for methionine and levoleucovorin

ArticleYear
Effect of dietary methyl group deficiency on folate metabolism in rats.
    The Journal of nutrition, 1989, Volume: 119, Issue:4

    Topics: Amino Acids; Animals; Choline Deficiency; Chromatography, High Pressure Liquid; Diet; Folic Acid; Leucovorin; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; Tetrahydrofolates

1989
Growth and DNA synthesis of folate- and methionine-depleted L1210 mouse leukemia cells in culture.
    Journal of nutritional science and vitaminology, 1987, Volume: 33, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; Deoxyuridine; DNA; Folic Acid; Leucovorin; Leukemia L1210; Methionine; Mice

1987
[Considerations on the clinical use of a new association of drugs in the treatment of hepatopathies].
    Minerva medica, 1968, Jun-09, Volume: 59, Issue:46

    Topics: Adolescent; Adult; Aged; Humans; Leucovorin; Liver Diseases; Methionine; Middle Aged; Niacinamide; Nucleosides; Vitamin B 12

1968
Translation of satellite tobacco necrosis virus ribonucleic acid. II. Initiation of in vitro translation in procaryotic and eucaryotic systems.
    Biochemistry, 1972, May-23, Volume: 11, Issue:11

    Topics: Alanine; Amino Acids; Bacterial Proteins; Carbon Isotopes; Cell Nucleus; Cell-Free System; Escherichia coli; Formates; Leucovorin; Methionine; NAD; Nicotiana; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Peptide Hydrolases; Plant Proteins; Plant Viruses; Plants; Plants, Toxic; RNA, Messenger; RNA, Transfer; RNA, Viral; Trimethoprim; Triticum; Tritium

1972
A patient with nonketotic hyperglycinemia: biochemical findings and therapeutic approaches.
    Pediatric research, 1974, Volume: 8, Issue:5

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Benzoates; Biopsy; Carbon Radioisotopes; Child, Preschool; Choline; Diet Therapy; Electroencephalography; Female; Folic Acid; Glycine; Humans; Infant; Infant, Newborn; Leucovorin; Liver; Methionine; Pyridoxine; Salicylates; Tetrahydrofolates

1974
Methionine transfer RNAs from the extreme halophile, Halobacterium cutirubrum.
    Biochimica et biophysica acta, 1972, Jul-31, Volume: 272, Issue:4

    Topics: Acyltransferases; Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Electrophoresis, Paper; Escherichia coli; Formates; Halobacterium; Leucovorin; Liver; Methionine; RNA, Bacterial; RNA, Transfer; Sulfur Isotopes; Tetrahydrofolates

1972
Formylation of mischarged E. coli tRNA Met f .
    FEBS letters, 1973, Mar-15, Volume: 30, Issue:3

    Topics: Amino Acyl-tRNA Synthetases; Autoradiography; Carbon Isotopes; Electrophoresis, Paper; Escherichia coli; Formates; Hydrolysis; Kinetics; Leucovorin; Methionine; Phenylalanine; RNA, Bacterial; RNA, Transfer; Valine; Yeasts

1973
Methionine transfer RNA from insect tissue.
    Journal of biochemistry, 1974, Volume: 76, Issue:1

    Topics: Amino Acyl-tRNA Synthetases; Bombyx; Carbon Radioisotopes; Chromatography, Ion Exchange; Escherichia coli; Formates; Leucovorin; Methionine; RNA, Transfer

1974
Effect of formylation on the chromatographic behavior of methionyl transfer ribonucleic acid.
    Analytical biochemistry, 1972, Volume: 47, Issue:1

    Topics: Amino Acyl-tRNA Synthetases; Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Clostridium; Enterococcus faecalis; Formates; Isotope Labeling; Leucovorin; Ligases; Methionine; RNA, Transfer; Tetrahydrofolates; Transferases; Tritium

1972
Methionine transfer ribonucleic acid from folate-sufficient and folate-deficient Streptococcus faecalis R.
    The Journal of biological chemistry, 1972, Nov-10, Volume: 247, Issue:21

    Topics: Acylation; Amino Acids; Amino Acyl-tRNA Synthetases; Ammonia; Carbon Isotopes; Chromatography, DEAE-Cellulose; Culture Media; Electrophoresis, Paper; Enterococcus faecalis; Escherichia coli; Folic Acid; Formates; Hydrolysis; Kinetics; Leucovorin; Methionine; Pancreas; Ribonucleases; RNA, Transfer; Salmonella typhimurium; Sulfur Isotopes; Tritium

1972
Chain initiation during polypeptide synthesis in cell-free bacterial systems programmed with plant viral messengers. II. The role of N-formylmethionine.
    Biochimica et biophysica acta, 1968, May-21, Volume: 157, Issue:3

    Topics: Amino Acids; Cell-Free System; Coliphages; Escherichia coli; Formates; Kinetics; Leucovorin; Magnesium; Methionine; Peptide Biosynthesis; Plant Viruses; RNA, Messenger; RNA, Transfer; RNA, Viral; Stimulation, Chemical; Sulfur Isotopes; Tobacco Mosaic Virus; Tritium

1968
The initiation of T4 deoxyribonucleic acid-dependent beta-glucosyltransferase synthesis in vitro.
    The Journal of biological chemistry, 1969, Oct-10, Volume: 244, Issue:19

    Topics: Coliphages; DNA, Viral; Escherichia coli; Folic Acid; Formates; Glucosyltransferases; Leucovorin; Magnesium; Methionine; Ribosomes; RNA, Bacterial; RNA, Transfer; Stimulation, Chemical; Templates, Genetic; Tritium; Viral Proteins

1969
Structure and function of E. coli formylmethionyl tRNA. I. Effect of modification of pyrimidine residues on aminoacyl synthetase recognition.
    Proceedings of the National Academy of Sciences of the United States of America, 1970, Volume: 66, Issue:2

    Topics: Amino Acids; Carbon Isotopes; Chromatography, DEAE-Cellulose; Escherichia coli; Formates; Homocysteine; Leucovorin; Ligases; Methionine; Nucleotides; Radiation Effects; Ribonucleases; RNA, Transfer; Spectrum Analysis; Transferases; Ultraviolet Rays

1970
Circular dichroism during deacylation of methionyl-tRNA met -f and formylmethionyl-tRNA met -f from E. coli.
    Biochemical and biophysical research communications, 1971, Jun-04, Volume: 43, Issue:5

    Topics: Acylation; Adenosine Triphosphate; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Circular Dichroism; Drug Stability; Escherichia coli; Formates; Hydrogen-Ion Concentration; Kinetics; Leucovorin; Methionine; Models, Biological; Peptides; Ribosomes; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Sulfhydryl Reagents; Tetroses; Ultraviolet Rays

1971
[A new hepatic therapeutic preparation. Its use in pediatrics].
    Minerva pediatrica, 1971, Oct-13, Volume: 23, Issue:41

    Topics: Child; Child, Preschool; Evaluation Studies as Topic; Humans; Infant; Injections, Intravenous; Leucovorin; Liver; Liver Diseases; Methionine; Nucleosides; Vitamins

1971
Vitamin B12-dependent replication of L1210 mouse leukemia cells. A model system for cobalamin-folate inter-relationships.
    The Journal of biological chemistry, 1981, Oct-25, Volume: 256, Issue:20

    Topics: Animals; Cell Division; Folic Acid; Kinetics; Leucovorin; Leukemia L1210; Methionine; Mice; Structure-Activity Relationship; Vitamin B 12

1981
Homocystinuria caused by 5,10-methylenetetrahydrofolate reductase deficiency: a case in an infant responding to methionine, folinic acid, pyridoxine, and vitamin B12 therapy.
    The Journal of pediatrics, 1981, Volume: 98, Issue:2

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alcohol Oxidoreductases; Amino Acids; Drug Therapy, Combination; Female; Folic Acid; Homocystinuria; Humans; Infant; Leucovorin; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Pyridoxine; Skin; Tetrahydrofolates; Vitamin B 12

1981
Methionine prevents nitrous oxide-induced teratogenicity in rat embryos grown in culture.
    Anesthesiology, 1994, Volume: 81, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Culture Techniques; Embryo, Mammalian; Female; Leucovorin; Male; Methionine; Models, Biological; Nitrous Oxide; Phenylephrine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Situs Inversus

1994
Valproate-induced developmental modifications maybe partially prevented by coadministration of folinic acid and S-adenosylmethionine.
    The International journal of developmental biology, 1996, Volume: Suppl 1

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Female; Fetus; Leucovorin; Liver; Methionine; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; S-Adenosylmethionine; Valproic Acid

1996
Cytotoxic synergism of methioninase in combination with 5-fluorouracil and folinic acid.
    Biochemical pharmacology, 2001, Apr-01, Volume: 61, Issue:7

    Topics: Antimetabolites, Antineoplastic; Carbon-Sulfur Lyases; Cell Division; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Leucovorin; Methionine; Recombinant Proteins; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured

2001
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
    American journal of human genetics, 2001, Volume: 69, Issue:1

    Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12

2001
EFFECT OF OROTIC ACID ON THE SYNTHESIS OF CITROVORUM FACTOR AND OF METHIONINE IN LIVER OF THE CHICK.
    Nature, 1963, Aug-17, Volume: 199

    Topics: Animals; Chickens; Corrinoids; Folic Acid; Leuconostoc; Leucovorin; Liver; Meat; Metabolism; Methionine; Orotic Acid; Pharmacology; Poultry; Proteins; Research; Vitamin B 12

1963
OROTIC ACID AND METABOLISM OF ONE CARBON UNIT: CONVERSION OF FOLIC ACID TO CITROVORUM FACTOR AND METHIONINE SYNTHESIS IN CHICK LIVER.
    Archives italiennes de biologie, 1963, Oct-05, Volume: 101

    Topics: Animals; Carbon; Chickens; Folic Acid; Homocysteine; Leuconostoc; Leucovorin; Liver; Metabolism; Methionine; Orotic Acid; Poultry; Proteins; Research; Serine; Vitamin B 12; Vitamin B 12 Deficiency

1963
EFFECT OF WATER-SOLUBLE VITAMINS ON RAT DIAPHRAGM CARBOHYDRATE METABOLISM.
    Archives of biochemistry and biophysics, 1964, Volume: 107

    Topics: 4-Aminobenzoic Acid; Ascorbic Acid; Carbohydrate Metabolism; Diaphragm; Folic Acid; Inositol; Leucovorin; Metabolism; Methionine; Muscles; Pantothenic Acid; Pharmacology; Pyridoxine; Rats; Research; Vitamins

1964
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:6

    Topics: Adenosine; Autistic Disorder; Betaine; Biomarkers; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cysteine; Female; Glutathione; Homocysteine; Humans; Leucovorin; Male; Methionine; Methylation; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12

2004
A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
    Human molecular genetics, 2013, Sep-15, Volume: 22, Issue:18

    Topics: Aminohydrolases; Animals; Cell Proliferation; Cells, Cultured; Choline; Congenital Abnormalities; Embryo Loss; Embryonic Development; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Gene Knock-In Techniques; Genetic Variation; Humans; Leucovorin; Leukocyte Count; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Models, Animal; Multienzyme Complexes; Multifunctional Enzymes; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Purines

2013
Adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin C deficiency.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:1

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antibodies, Monoclonal, Humanized; Betaine; Biopsy; Carrier Proteins; Diagnosis, Differential; Drug Resistance; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Hypertension, Malignant; Immunologic Factors; Kidney; Kidney Function Tests; Leucovorin; Lipotropic Agents; Male; Methionine; Methylmalonic Acid; Mutation; Oxidoreductases; Recurrence; Renal Dialysis; Treatment Outcome; Vitamin B 12 Deficiency; Vitamin B Complex

2014
Serine hydroxymethyltransferase: a key player connecting purine, folate and methionine metabolism in Saccharomyces cerevisiae.
    Current genetics, 2015, Volume: 61, Issue:4

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aminoimidazole Carboxamide; Carbon-Nitrogen Ligases; Folic Acid; Gene Expression Regulation, Fungal; Glycine Hydroxymethyltransferase; Histidine; Leucovorin; Methionine; Mutation; Purines; Ribonucleotides; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tetrahydrofolates; Thymidine; Trans-Activators; Transcriptional Activation

2015
Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells.
    Nutrients, 2018, Mar-24, Volume: 10, Issue:4

    Topics: Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Leucovorin; Methionine; Methylation; Protein Processing, Post-Translational; S-Adenosylhomocysteine

2018
Stage IV Pancreatic Cancer Patient Treated With FOLFIRINOX Combined With Oral Methioninase: A Highly-Rare Case With Long-term Stable Disease.
    Anticancer research, 2022, Volume: 42, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carbon-Sulfur Lyases; Disease Models, Animal; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Methionine; Mice; Mice, Nude; Oxaliplatin; Pancreatic Neoplasms; Xenograft Model Antitumor Assays

2022