Page last updated: 2024-08-17

methionine and levodopa

methionine has been researched along with levodopa in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19908 (28.57)18.7374
1990's5 (17.86)18.2507
2000's7 (25.00)29.6817
2010's7 (25.00)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Baldessarini, RJ; Lipinski, JF; Stramentinoli, G1
Atkins, HL; Som, P1
Ordonez, LA; Wurtman, RJ1
Antal, J; Jászsági-Nagy, E1
Baldessarini, RJ1
Långström, B1
Hyland, K; Surtees, R1
Gibson, J; Van der Westhuyzen, J1
Bone, AH; Taufek, HR2
Janardhanan, K; Siddhuraju, P; Vijayakumari, K1
Benson, R; Charlton, C; Crowell, B; Doonquah, K; Hill, B1
Hartvig, P; Hedlund, C; Långström, B; Lindner, KJ; Tyrefors, N1
Bottiglieri, T; Bressman, S; Di Rocco, A; Prikhojan, A; Rempel, N; Werner, P; Yahr, MD1
Müller, T1
Fowler, B; Hauptmann, B; Kuhn, W; Müller, T; Woitalla, D1
Atluri, H; Mitra, AK; Talluri, RS1
Binelli, S; Bugiani, O; Capobianco, R; Di Fede, G; Fociani, P; Giaccone, G; Grisoli, M; Limido, L; Mangieri, M; Suardi, S; Tagliavini, F1
Camargos, ST; Cardoso, F; Gianetti, JG; Hardy, J; Lees, A; Momeni, P; Singleton, A1
Abe, T; Isobe, C; Terayama, Y1
Cacciatore, I; Cerasa, LS; Cornacchia, C; Di Stefano, A; Fontana, A; Iannitelli, A; Mollica, A; Nasuti, C; Pinnen, F; Sozio, P1
Agid, Y; Bellanger, A; Ben Djebara, M; Bonnet, AM; Bonnet, C; Charbonnier-Beaupel, F; Corvol, JC; Costentin, J; Fiévet, MH; Hartmann, A; Hulot, JS; Lacomblez, L; Meliksetyan, G; Roze, E; Vidailhet, M; Vrignaud, C; Zahr, N1
Chung, HY; Jeong, HO; Park, D; Qian, GY; Si, YX; Wang, ZJ; Yang, JM; Ye, S; Yin, SJ1
Andréasson, M; Brodin, L; Laffita-Mesa, JM; Svenningsson, P1
Ares-Pensado, B; Castro, A; Fernandez-Pajarin, G; Rivero-de-Aguilar, A; Sesar, A1
Cui, C; Han, Y; Li, G; Li, H; Yu, H; Zhang, B1

Reviews

3 review(s) available for methionine and levodopa

ArticleYear
Biological transmethylation involving S-adenosylmethionine: development of assay methods and implications for neuropsychiatry.
    International review of neurobiology, 1975, Volume: 18

    Topics: Acetylserotonin O-Methyltransferase; Animals; Apomorphine; Blood Platelets; Brain; Histamine; Humans; Leukemia; Levodopa; Methionine; Methionine Adenosyltransferase; Methyltransferases; Monoamine Oxidase Inhibitors; Pyrogallol; Rabbits; Rats; S-Adenosylmethionine; Schizophrenia; Serotonin; Tetrahydrofolates

1975
Design of molecules labeled with beta+ emitters for use in multitracer investigations using positron emission tomography.
    Acta radiologica. Supplementum, 1990, Volume: 374

    Topics: Beta Particles; Humans; Isotope Labeling; Levodopa; Methionine; Neurotransmitter Agents; Nomifensine; Raclopride; Salicylamides; Spiperone; Tomography, Emission-Computed

1990
Non-dopaminergic drug treatment of Parkinson's disease.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:4

    Topics: Adenosine; Adrenergic alpha-Antagonists; Body Weight; Cholinergic Antagonists; Homocysteine; Humans; Levodopa; Methionine; N-Methylaspartate; Parkinson Disease; Piperidines; Serotonin Receptor Agonists

2001

Trials

1 trial(s) available for methionine and levodopa

ArticleYear
The COMT Val158Met polymorphism affects the response to entacapone in Parkinson's disease: a randomized crossover clinical trial.
    Annals of neurology, 2011, Volume: 69, Issue:1

    Topics: Aged; Antiparkinson Agents; Biological Availability; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Female; Genotype; Humans; Levodopa; Male; Methionine; Middle Aged; Nitriles; Parkinson Disease; Pharmacogenetics; Polymorphism, Genetic; Valine

2011

Other Studies

24 other study(ies) available for methionine and levodopa

ArticleYear
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis

2001
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Methylation hypothesis.
    Archives of general psychiatry, 1979, Volume: 36, Issue:3

    Topics: Adult; Animals; Brain; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Liver; Lung; Male; Methionine; Methylation; Mice; Rabbits; Rats; S-Adenosylmethionine; Tryptamines

1979
Growth-hormone and somatostatin effects on [75Se]selenomethionine uptake by the pancreas.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1979, Volume: 20, Issue:6

    Topics: Animals; Apomorphine; Autoradiography; Carbon Radioisotopes; Dogs; Growth Hormone; Intestinal Mucosa; Kidney; Levodopa; Liver; Methionine; Mice; Pancreas; Radioisotopes; Selenium; Selenomethionine; Somatostatin

1979
Effects of exogenous L-dopa on the metabolism of methionine and S-adenosylmethionine in the brain.
    Monographien aus dem Gesamtgebiete der Psychiatrie, 1978, Volume: 18

    Topics: Animals; Brain; Levodopa; Methionine; Methylation; Rats; S-Adenosylmethionine

1978
[The effect of L-dopa and reserpine on the accumulation of 14C-methionine 14C-phenylalanine in the brain regions of rats].
    Radiobiologia, radiotherapia, 1978, Volume: 19, Issue:4

    Topics: Animals; Brain; Carbon Radioisotopes; Levodopa; Male; Methionine; Phenylalanine; Rats; Reserpine

1978
L-3,4-dihydroxyphenylalanine (levodopa) lowers central nervous system S-adenosylmethionine concentrations in humans.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:7

    Topics: Adolescent; Akinetic Mutism; Biopterins; Child, Preschool; Humans; Infant; Levodopa; Methionine; NADH, NADPH Oxidoreductases; Phenylketonurias; Pyridoxine; S-Adenosylmethionine; Tetrahydrofolates; Tyrosine

1990
Effect of L-dihydroxyphenylalanine (L-dopa) and methionine on tissue S-adenosylmethionine concentrations in cobalamin-inactivated fruit bats.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1984, Volume: 54, Issue:4

    Topics: Animals; Brain; Chiroptera; Levodopa; Liver; Methionine; Nervous System; Nitrous Oxide; S-Adenosylmethionine; Vitamin B 12 Deficiency

1984
The inhibitory action of L-dihydroxyphenylalanine (L-dopa) in the presence of a monoamine oxidase inhibitor on protein synthesis in vivo and the partial amelioration of this by methionine supplementation.
    The Biochemical journal, 1980, Nov-15, Volume: 192, Issue:2

    Topics: Age Factors; Animals; Brain; Depression, Chemical; Iproniazid; Kidney; Kinetics; Levodopa; Liver; Male; Methionine; Protein Biosynthesis; Rats; Subcellular Fractions

1980
Influence of exogenous L-3,4,-dihydroxyphenylalanine (L-dopa) on the methionine and s-adenosylmethionine concentrations in the brain and other tissues [proceedings].
    Biochemical Society transactions, 1980, Volume: 8, Issue:1

    Topics: Aging; Animals; Brain; Iproniazid; Kidney; Levodopa; Liver; Methionine; Organ Specificity; Rats; S-Adenosylmethionine

1980
Chemical analysis and nutritional assessment of the less known pulses, Vigna aconitifolia (Jacq.) Marechal and Vigna vexillata (L.) A. Rich.
    Plant foods for human nutrition (Dordrecht, Netherlands), 1994, Volume: 45, Issue:2

    Topics: Amino Acids; Cystine; Fabaceae; Fatty Acids; India; Levodopa; Methionine; Minerals; Nutritive Value; Plant Proteins; Plants, Medicinal; Seeds

1994
The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance.
    Neurochemical research, 1993, Volume: 18, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain; Chromatography, High Pressure Liquid; Drug Interactions; Levodopa; Male; Methionine; Methionine Adenosyltransferase; Mice; Parkinson Disease; S-Adenosylmethionine

1993
An automated liquid chromatographic plasma analysis of amino acids used in combination with positron emission tomography (PET) for determination of in vivo plasma kinetics.
    Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:4-5

    Topics: 5-Hydroxytryptophan; Amino Acids; Autoanalysis; Blood Proteins; Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Levodopa; Methionine; Molecular Weight; Robotics; Tomography, Emission-Computed

1995
COMT-dependent protection of dopaminergic neurons by methionine, dimethionine and S-adenosylmethionine (SAM) against L-dopa toxicity in vitro.
    Brain research, 2001, Mar-02, Volume: 893, Issue:1-2

    Topics: Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Survival; Cells, Cultured; Dopamine; Enzyme Inhibitors; Levodopa; Methionine; Neurons; Neuroprotective Agents; Rats; S-Adenosylmethionine

2001
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease.
    Neuroscience letters, 2001, Jul-27, Volume: 308, Issue:1

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Cardiovascular Diseases; Dopa Decarboxylase; Down-Regulation; Drug Interactions; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Parkinson Disease; S-Adenosylmethionine; Up-Regulation

2001
Functional activity of a large neutral amino acid transporter (LAT) in rabbit retina: a study involving the in vivo retinal uptake and vitreal pharmacokinetics of L-phenyl alanine.
    International journal of pharmaceutics, 2008, Jan-22, Volume: 347, Issue:1-2

    Topics: Alanine; Amino Acid Transport System L; Amino Acids; Amino Acids, Cyclic; Aminoisobutyric Acids; Animals; Area Under Curve; Binding, Competitive; Gene Expression; Large Neutral Amino Acid-Transporter 1; Levodopa; Male; Membrane Transport Modulators; Methionine; Phenylalanine; Protein Isoforms; Rabbits; Retina

2008
A novel phenotype of sporadic Creutzfeldt-Jakob disease.
    Journal of neurology, neurosurgery, and psychiatry, 2007, Volume: 78, Issue:12

    Topics: Aged; Antibodies; Antibodies, Monoclonal; Antiparkinson Agents; Blotting, Western; Brain; Codon; Creutzfeldt-Jakob Syndrome; Female; Humans; Immunohistochemistry; Levodopa; Magnetic Resonance Imaging; Methionine; Parkinsonian Disorders; Phenotype; Polymorphism, Genetic; PrPSc Proteins; Valine

2007
Novel GCH1 mutation in a Brazilian family with dopa-responsive dystonia.
    Movement disorders : official journal of the Movement Disorder Society, 2008, Jan-30, Volume: 23, Issue:2

    Topics: Arginine; Brazil; Dopamine Agents; Dystonia; Family Health; GTP Cyclohydrolase; Humans; Levodopa; Lysine; Methionine; Mutation; Valine

2008
L-Dopa therapy increases homocysteine concentration in cerebrospinal fluid from patients with Parkinson's disease.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:6

    Topics: Aged; Antiparkinson Agents; Case-Control Studies; Female; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Parkinson Disease; Statistics, Nonparametric

2010
CNS delivery of L-dopa by a new hybrid glutathione-methionine peptidomimetic prodrug.
    Amino acids, 2012, Volume: 42, Issue:1

    Topics: Animals; Central Nervous System; Chromatography, High Pressure Liquid; Glutathione; Humans; Hydrolysis; Kinetics; Levodopa; Male; Methionine; Peptides; Prodrugs; Rats; Rats, Wistar; Solubility

2012
Effects of isorhamnetin on tyrosinase: inhibition kinetics and computational simulation.
    Bioscience, biotechnology, and biochemistry, 2012, Volume: 76, Issue:6

    Topics: Agaricales; Anilino Naphthalenesulfonates; Computer Simulation; Enzyme Inhibitors; Fluorescent Dyes; Fungal Proteins; Histidine; Kinetics; Levodopa; Methionine; Models, Molecular; Monophenol Monooxygenase; Protein Structure, Tertiary; Quercetin; Thermodynamics

2012
Correlations Between Methionine Cycle Metabolism, COMT Genotype, and Polyneuropathy in L-Dopa Treated Parkinson's Disease: A Preliminary Cross-Sectional Study.
    Journal of Parkinson's disease, 2017, Volume: 7, Issue:4

    Topics: Aged; Catechol O-Methyltransferase; Cognition Disorders; Cross-Sectional Studies; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Single Nucleotide; Polyneuropathies; Statistics, Nonparametric; Vitamins

2017
[Chronic inflammatory demyelinating polyradiculoneuropathy associated with treatment using intraduodenal infusion of levodopa-carbidopa].
    Revista de neurologia, 2019, 10-01, Volume: 69, Issue:7

    Topics: Antiparkinson Agents; Carbidopa; Diagnosis, Differential; Dopamine; Drug Combinations; Duodenum; Female; Folic Acid; Humans; Infusions, Parenteral; Levodopa; Metabolic Networks and Pathways; Methionine; Middle Aged; Parkinson Disease; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

2019
Curcumin-driven reprogramming of the gut microbiota and metabolome ameliorates motor deficits and neuroinflammation in a mouse model of Parkinson's disease.
    Frontiers in cellular and infection microbiology, 2022, Volume: 12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Creatine; Curcumin; Disease Models, Animal; Gastrointestinal Microbiome; Levodopa; Metabolome; Methionine; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Neuroprotective Agents; Parkinson Disease; RNA, Ribosomal, 16S; Sarcosine

2022