Page last updated: 2024-08-17

methionine and hypochlorous acid

methionine has been researched along with hypochlorous acid in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19906 (10.34)18.7374
1990's20 (34.48)18.2507
2000's21 (36.21)29.6817
2010's10 (17.24)24.3611
2020's1 (1.72)2.80

Authors

AuthorsStudies
Kalra, J; Kapoor, R; Prasad, K2
Vissers, MC; Winterbourn, CC1
Browne, K; Cochrane, CG; Harris, A; Hyslop, PA; Jackson, JH; Quehenberger, O; Schraufstätter, IU1
Chaudhary, AK; Debnath, D; Kalra, J; Prasad, K1
Egan, RW; Gale, PH; Hagmann, WK1
Kraemer, R; Mullane, KM; Seligmann, B1
Ballestrero, A; Dallegri, F; Ferrando, F; Ottonello, L; Patrone, F1
Stern, A; Winterbourn, CC1
Fliss, H1
Eicher, AL; Fellman, JH; Green, TR1
Collins-Lech, C; Sohnle, PG; Wagner, DK1
Tsan, MF1
Hesse, D; Vogt, W1
Dai, J; Dhalla, V; Meij, JT; Panagia, V1
Fliss, H; Ménard, M1
Kettle, AJ; Winterbourn, CC1
Kuypers, F; Stern, A; van den Berg, J; Vissers, MC; Winterbourn, CC1
Hess, ML; Ito, H; Kukreja, RC; Manson, NH; Norisue, M; Okabe, E; Takahashi, S1
Davis, WB; Herzyk, DJ; She, ZW; Wewers, MD1
Bagchi, D; Bagchi, M; Stohs, SJ1
Blackburn, AC; Buffinton, GD; Doe, WF1
Dhalla, NS; Elimban, V; Kato, K; Lukas, A; Shao, Q1
Dhalla, NS; Elimban, V; Persad, S; Siddiqui, F1
Davies, MJ; Hazell, LJ; Stocker, R1
Arnhold, J; Panasenko, OM1
Fritz, G; Glatter, O; Hammel, M; Jerlich, A; Kharrazi, H; Schaur, RJ; Tschabuschnig, S1
Carr, AC; Frei, B; Hawkins, CL; Stocker, R; Thomas, SR1
Peskin, AV; Winterbourn, CC3
Abuja, PM; Fabjan, JS; Schaur, RJ; Sevanian, A1
Colombo, R; Dalle-Donne, I; Di Simplicio, P; Gagliano, N; Giustarini, D; Lusini, L; Milzani, A; Rossi, R1
Britigan, BE; Burns, CP; McCormick, ML; Reszka, KJ; Wagner, BA1
Auchère, F; Capeillère-Blandin, C1
Friesen, MD; Ohshima, H; Suzuki, T1
Fu, X; Heinecke, JW; Kassim, SY; Parks, WC1
Fisher, MT; Khor, HK; Schöneich, C1
Belaaouaj, A; Fu, X; Heinecke, JW; Shao, B; Verlinde, CL1
Cheah, FC; Midwinter, RG; Moskovitz, J; Vissers, MC; Winterbourn, CC1
Bao, S; Ramanadham, S; Song, H; Turk, J1
Doherty-Kirby, A; Haines, T; Lajoie, G; Liu, S; Manzanares, D; Possmayer, F; Ramos, Y; Rodriguez-Capote, K; Zhao, L1
Anderson, R; Potjo, M; Theron, AJ; Tintinger, GR1
Iakhiaev, AV; Nalian, A1
Davies, MJ; Ellis, NA; Hawkins, CL; Pattison, DI; Szuchman-Sapir, AJ; Witting, PK1
Chen, J; Chung, DW; Fu, X; Kulman, J; Ling, M; López, JA; McMullen, B; Wang, Y1
Brot, N; Fu, X; Heinecke, JW; Klebanoff, SJ; Rosen, H; Wang, Y1
Ashby, MT; Beal, JL; Foster, SB1
Akutsu, H; Hayashi, T; Nakamura, M; Nunomura, A; Perry, G; Shishido, N; Smith, MA1
Hagedorn, TD; Hogan, KM; Kim, SB; Landino, LM1
Chen, J; Chung, DW; Fu, X; Gallagher, R; López, JA; Zheng, Y1
Bach, NC; Drazic, A; Kriehuber, T; Le, Y; Miura, H; Peschek, J; Winter, J1
Bepperling, A; Drazic, A; Gebendorfer, KM; Krause, M; Mak, S; Steiner, A; Winter, J1
Davies, MJ; Pattison, DI; Storkey, C1
Chen, J; Chung, DW; Fu, X; Ling, M; López, JA; Wang, Y1
Agrebi, R; Barras, F; Bos, J; Collet, JF; Espinosa, L; Ezraty, B; Gennaris, A; Henry, C; Iranzo, O; Leverrier, P; Oheix, E; Szewczyk, J; Vergnes, A; Vertommen, D1
Ahn, J; Ha, NC; Hong, S; Jo, I; Kim, D; No, T; Ryu, S1
Chuang, CY; Davies, MJ; Gamon, LF; Hawkins, CL; Malle, E; Xu, S1

Other Studies

58 other study(ies) available for methionine and hypochlorous acid

ArticleYear
Beneficial effects of methionine on myocardial hemodynamic and cellular functions in hemorrhagic shock.
    Angiology, 1992, Volume: 43, Issue:4

    Topics: Animals; Blood Gas Analysis; Creatine Kinase; Dogs; Drug Evaluation, Preclinical; Female; Heart; Hemodynamics; Hypochlorous Acid; Isoenzymes; Lactates; Lactic Acid; Male; Methionine; Myocardium; Reperfusion; Shock, Hemorrhagic

1992
Methionine in protection of hemorrhagic shock: role of oxygen free radicals and hypochlorous acid.
    Circulatory shock, 1992, Volume: 36, Issue:4

    Topics: Animals; Dogs; Free Radicals; Hemodynamics; Hypochlorous Acid; Leukocyte Count; Malondialdehyde; Methionine; Myocardial Contraction; Myocardium; Neutrophils; Oxygen; Shock, Hemorrhagic

1992
Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl.
    Archives of biochemistry and biophysics, 1991, Feb-15, Volume: 285, Issue:1

    Topics: Azides; Chloramines; Fibronectins; Fluorescence; Humans; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Molecular Weight; Neutrophils; Pancreatic Elastase; Peroxidase; Protein Denaturation; Tryptophan; Tyrosine

1991
Mechanisms of hypochlorite injury of target cells.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:2

    Topics: Animals; Cell Survival; Cells, Cultured; Chloramines; Glucose; Glycolysis; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Mice; Oxidation-Reduction; Potassium; Sulfhydryl Compounds; Tryptophan; Tumor Cells, Cultured

1990
Effect of polymorphonuclear leukocyte-derived oxygen free radicals and hypochlorous acid on cardiac function and some biochemical parameters.
    American heart journal, 1990, Volume: 119, Issue:3 Pt 1

    Topics: Animals; Azides; Catalase; Dogs; Female; Free Radicals; Hypochlorous Acid; Lactates; Lactic Acid; Lymphocyte Activation; Male; Malondialdehyde; Methionine; Myocardial Contraction; Neutrophils; Oxygen; Sodium Azide; Superoxide Dismutase; Vascular Resistance; Zymosan

1990
Naphthalenes as inhibitors of myeloperoxidase: direct and indirect mechanisms of inhibition.
    Agents and actions, 1990, Volume: 29, Issue:3-4

    Topics: alpha 1-Antitrypsin; Animals; Binding Sites; Dianisidine; Dogs; Hydrogen Peroxide; Hypochlorous Acid; Leukocyte Elastase; Methionine; Molecular Structure; Naphthalenes; Oxidation-Reduction; Pancreatic Elastase; Peroxidase; Structure-Activity Relationship

1990
Polymorphonuclear leukocytes reduce cardiac function in vitro by release of H2O2.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 2

    Topics: Animals; Anions; Catalase; Cell Aggregation; Heart; Histamine; Hydrogen Peroxide; Hypochlorous Acid; Mannitol; Methionine; Myocardial Contraction; Neutrophils; Papillary Muscles; Superoxide Dismutase

1990
Effector-target co-aggregation as a crucial step in the neutrophil-mediated tumour cell lysis.
    Journal of clinical & laboratory immunology, 1989, Volume: 30, Issue:3

    Topics: Antibodies, Monoclonal; Antigens, Differentiation; Burkitt Lymphoma; Cell Aggregation; Cytotoxicity, Immunologic; Humans; Hypochlorous Acid; Lymphocyte Function-Associated Antigen-1; Male; Methionine; Neutrophils; Receptors, Leukocyte-Adhesion; Taurine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical.
    The Journal of clinical investigation, 1987, Volume: 80, Issue:5

    Topics: Amitrole; Catalase; Cytochrome c Group; Erythrocytes; Glutathione; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Methionine; Neutrophils; Nitroblue Tetrazolium; Oxidation-Reduction; Spectrophotometry; Superoxide Dismutase; Superoxides

1987
Oxidation of proteins in rat heart and lungs by polymorphonuclear leukocyte oxidants.
    Molecular and cellular biochemistry, 1988, Volume: 84, Issue:2

    Topics: Animals; Cells, Cultured; Cysteine; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Lung; Male; Methionine; Myocardium; Neutrophils; Oxidation-Reduction; Proteins; Rats; Rats, Inbred Strains

1988
Myeloperoxidase oxidation of sulfur-centered and benzoic acid hydroxyl radical scavengers.
    FEBS letters, 1985, Nov-11, Volume: 192, Issue:1

    Topics: Benzoates; Benzoic Acid; Binding, Competitive; Dimethyl Sulfoxide; Humans; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Mannitol; Methionine; Neutrophils; Oxidation-Reduction; Peroxidase; Sulfur; Superoxide Dismutase; Taurine

1985
Inhibition of neutrophil killing of Candida albicans pseudohyphae by substances which quench hypochlorous acid and chloramines.
    Infection and immunity, 1986, Volume: 51, Issue:3

    Topics: Alanine; Candida albicans; Chloramines; Humans; Hypochlorous Acid; Mannitol; Methionine; Neutrophils; Oxidation-Reduction; Peroxidase; Superoxides; Tryptophan

1986
Myeloperoxidase-mediated oxidation of methionine.
    Journal of cellular physiology, 1982, Volume: 111, Issue:1

    Topics: Animals; Deuterium; Dogs; Hydrogen-Ion Concentration; Hypochlorous Acid; Kinetics; Leukocytes; Methionine; Oxidation-Reduction; Peroxidase; Peroxidases

1982
Oxidants generated by the myeloperoxidase-halide system activate the fifth component of human complement, C5.
    Immunobiology, 1994, Volume: 192, Issue:1-2

    Topics: Complement Activation; Complement C5; Electrophoresis, Polyacrylamide Gel; Humans; Hypochlorous Acid; Methionine; Neutrophils; Oxidation-Reduction; Peroxidase; Taurine

1994
Involvement of thiol groups in the impairment of cardiac sarcoplasmic reticular phospholipase D activity by oxidants.
    Journal of lipid mediators and cell signalling, 1995, Volume: 11, Issue:2

    Topics: Animals; Catalase; Dithiothreitol; Glutathione; Hydrogen Peroxide; Hypochlorous Acid; Male; Methionine; Myocardium; Oxidants; Oxidation-Reduction; Phospholipase D; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Structure-Activity Relationship; Sulfhydryl Compounds

1995
Rapid neutrophil accumulation and protein oxidation in irradiated rat lungs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:6

    Topics: Animals; Blood Cell Count; Cell Movement; Hypochlorous Acid; Leukocyte Count; Lung; Male; Methionine; Neutrophils; Oxidation-Reduction; Oxidoreductases; Proteins; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Time Factors

1994
Assays for the chlorination activity of myeloperoxidase.
    Methods in enzymology, 1994, Volume: 233

    Topics: Animals; Cattle; Chlorides; Electrochemistry; Electrodes; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hypochlorous Acid; Indicators and Reagents; Kinetics; Methionine; Neutrophils; Peroxidase; Spleen; Taurine

1994
Membrane changes associated with lysis of red blood cells by hypochlorous acid.
    Free radical biology & medicine, 1994, Volume: 16, Issue:6

    Topics: Diamide; Electrophoresis, Polyacrylamide Gel; Erythrocyte Deformability; Erythrocyte Membrane; Erythrocytes; Ethylmaleimide; Free Radical Scavengers; Hemolysis; Humans; Hypochlorous Acid; Kinetics; Membrane Proteins; Methionine; Microscopy, Electron; Osmolar Concentration; Potassium; Sulfhydryl Compounds; Taurine; Time Factors

1994
The effect of hypochlorous acid and hydrogen peroxide on coronary flow and arrhythmogenesis in myocardial ischemia and reperfusion.
    European journal of pharmacology, 1993, Jun-01, Volume: 248, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Male; Methionine; Myocardial Ischemia; Myocardial Reperfusion; Perfusion; Rats; Rats, Sprague-Dawley

1993
Tumor necrosis factor increases the elastolytic potential of adherent neutrophils: a role for hypochlorous acid.
    American journal of respiratory cell and molecular biology, 1993, Volume: 9, Issue:4

    Topics: Cell Adhesion; Elasticity; Elastin; Humans; Hypochlorous Acid; Methionine; Neutrophils; Protease Inhibitors; Tumor Necrosis Factor-alpha

1993
Comparative in vitro oxygen radical scavenging ability of zinc methionine and selected zinc salts and antioxidants.
    General pharmacology, 1997, Volume: 28, Issue:1

    Topics: Animals; Antioxidants; Free Radical Scavengers; Hydroxyl Radical; Hypochlorous Acid; L-Lactate Dehydrogenase; Methionine; Organometallic Compounds; PC12 Cells; Rats; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Zinc

1997
Salicylate hydroxylation as an indicator of hydroxyl radical generation in dextran sulfate-induced colitis.
    Free radical biology & medicine, 1998, Volume: 25, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Colitis; Dextran Sulfate; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Hypochlorous Acid; Intestinal Mucosa; Kinetics; Male; Methionine; Mice; Mice, Inbred CBA; Peroxidase; Salicylates; Salicylic Acid

1998
Mechanism of depression in cardiac sarcolemmal Na+-K+-ATPase by hypochlorous acid.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Adenosine Triphosphate; Animals; Binding Sites; Dithiothreitol; Hypochlorous Acid; Kinetics; Methionine; Myocardium; Ouabain; Sarcolemma; Sodium-Potassium-Exchanging ATPase; Swine

1998
Alterations in cardiac membrane beta-adrenoceptors and adenylyl cyclase due to hypochlorous acid.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hypochlorous Acid; Immunoblotting; Isoproterenol; Lipid Peroxidation; Methionine; Myocardium; Pertussis Toxin; Pindolol; Propane; Rats; Receptors, Adrenergic; Sodium Fluoride; Virulence Factors, Bordetella

1999
Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins.
    The Biochemical journal, 1999, May-01, Volume: 339 ( Pt 3)

    Topics: Apolipoprotein B-100; Apolipoproteins B; Chloramines; Chlorides; Cholesterol Esters; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Electrons; Female; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hypochlorous Acid; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Male; Methionine; Oxidants; Peroxidase; Tryptophan; Vitamin E

1999
Linoleic acid hydroperoxide favours hypochlorite- and myeloperoxidase-induced lipid peroxidation.
    Free radical research, 1999, Volume: 30, Issue:6

    Topics: Butylated Hydroxytoluene; Chlorides; Free Radical Scavengers; Free Radicals; Glycine max; Hydrogen Peroxide; Hypochlorous Acid; Linoleic Acids; Lipid Peroxidation; Lipid Peroxides; Liposomes; Mannitol; Methionine; Peroxidase; Phosphatidylcholines; Sodium Azide; Taurine; Thiobarbituric Acid Reactive Substances

1999
Comparison of HOCl traps with myeloperoxidase inhibitors in prevention of low density lipoprotein oxidation.
    Biochimica et biophysica acta, 2000, Aug-31, Volume: 1481, Issue:1

    Topics: Arteriosclerosis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescence; Glycine; Humans; Hydroxamic Acids; Hydroxybenzoates; Hypochlorous Acid; Lipoproteins, LDL; Methionine; Neutrophils; Peroxidase; Potassium Cyanide; Salicylamides; Sodium Azide; Taurine; Tryptophan

2000
Relative reactivities of N-chloramines and hypochlorous acid with human plasma constituents.
    Free radical biology & medicine, 2001, Mar-01, Volume: 30, Issue:5

    Topics: alpha 1-Antitrypsin; Ascorbic Acid; Chloramines; Female; Free Radicals; Humans; Hypochlorous Acid; In Vitro Techniques; Male; Methionine; Oxidants; Serum Albumin; Sulfhydryl Compounds; Taurine

2001
Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate.
    Free radical biology & medicine, 2001, Mar-01, Volume: 30, Issue:5

    Topics: Amino Acids; Ascorbic Acid; Chloramines; Hydrogen-Ion Concentration; Hypochlorous Acid; In Vitro Techniques; Kinetics; Methionine; Oxidants; Oxidation-Reduction; Sulfhydryl Compounds

2001
Hypochlorite induces the formation of LDL(-), a potentially atherogenic low density lipoprotein subspecies.
    FEBS letters, 2001, Jun-15, Volume: 499, Issue:1-2

    Topics: Arteriosclerosis; Chloramines; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Hypochlorous Acid; Lipoproteins, LDL; Methionine; Oxidants; Oxidation-Reduction; Plasma; Static Electricity; Time Factors

2001
Actin carbonylation: from a simple marker of protein oxidation to relevant signs of severe functional impairment.
    Free radical biology & medicine, 2001, Nov-01, Volume: 31, Issue:9

    Topics: Actin Cytoskeleton; Actins; Animals; Biomarkers; Carbonic Acid; Cross-Linking Reagents; Cysteine; Fluorometry; Hypochlorous Acid; In Vitro Techniques; Methionine; Muscle, Skeletal; Oxidation-Reduction; Rabbits; Tyrosine

2001
Hydrogen peroxide-induced apoptosis of HL-60 human leukemia cells is mediated by the oxidants hypochlorous acid and chloramines.
    Archives of biochemistry and biophysics, 2002, May-15, Volume: 401, Issue:2

    Topics: Apoptosis; Chloramines; Chlorides; Culture Media; HL-60 Cells; Humans; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Models, Biological; Necrosis; Nitrobenzoates; Oxidants; Sulfhydryl Compounds

2002
Oxidation of Cu, Zn-superoxide dismutase by the myeloperoxidase/hydrogen peroxide/chloride system: functional and structural effects.
    Free radical research, 2002, Volume: 36, Issue:11

    Topics: Animals; Cattle; Copper; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Hydrazines; Hydrogen Peroxide; Hypochlorous Acid; Isoelectric Focusing; Lysine; Methionine; Oxidation-Reduction; Peroxidase; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Tyrosine; Zinc

2002
Identification of products formed by reaction of 3',5'-di-O-acetyl-2'-deoxyguanosine with hypochlorous acid or a myeloperoxidase-H2O2-Cl- system.
    Chemical research in toxicology, 2003, Volume: 16, Issue:3

    Topics: Deoxyguanosine; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypochlorous Acid; Imidazoles; Methionine; Nicotine; Peroxidase; Sodium Chloride; Spectrometry, Mass, Electrospray Ionization

2003
Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation.
    The Journal of biological chemistry, 2003, Aug-01, Volume: 278, Issue:31

    Topics: Amino Acid Sequence; Catalytic Domain; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Glycine; Humans; Hydrogen Peroxide; Hypochlorous Acid; Mass Spectrometry; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Methionine; Oxidation-Reduction; Peptide Fragments; Peroxidase; Structure-Activity Relationship; Trypsin; Tryptophan

2003
Histamine chloramine reactivity with thiol compounds, ascorbate, and methionine and with intracellular glutathione.
    Free radical biology & medicine, 2003, Nov-15, Volume: 35, Issue:10

    Topics: Ascorbic Acid; Cell Division; Cells, Cultured; Chloramines; Fibroblasts; Glutathione; Histamine; Humans; Hypochlorous Acid; Kinetics; Methionine; Oxidants; Oxidation-Reduction; Skin; Sulfhydryl Compounds

2003
Potential role of methionine sulfoxide in the inactivation of the chaperone GroEL by hypochlorous acid (HOCl) and peroxynitrite (ONOO-).
    The Journal of biological chemistry, 2004, May-07, Volume: 279, Issue:19

    Topics: Amino Acid Sequence; Arteriosclerosis; Chaperonin 60; Chromatography; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Hydrolysis; Hypochlorous Acid; Mass Spectrometry; Methionine; Methionine Sulfoxide Reductases; Molecular Chaperones; Molecular Sequence Data; Oxidants; Oxidoreductases; Oxygen; Peptides; Peroxynitrous Acid; Phagocytes; Protein Binding; Time Factors; Trypsin; Tyrosine

2004
Methionine sulfoxide and proteolytic cleavage contribute to the inactivation of cathepsin G by hypochlorous acid: an oxidative mechanism for regulation of serine proteinases by myeloperoxidase.
    The Journal of biological chemistry, 2005, Aug-12, Volume: 280, Issue:32

    Topics: Animals; Catalytic Domain; Cathepsin G; Cathepsins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Mass Spectrometry; Methionine; Mice; Models, Chemical; Models, Molecular; Neutrophils; Oxidants; Oxygen; Peptides; Peroxidase; Protein Binding; Serine Endopeptidases; Spectrometry, Mass, Electrospray Ionization; Time Factors

2005
Taurine chloramine is more selective than hypochlorous acid at targeting critical cysteines and inactivating creatine kinase and glyceraldehyde-3-phosphate dehydrogenase.
    Free radical biology & medicine, 2006, Jan-01, Volume: 40, Issue:1

    Topics: Animals; Binding, Competitive; Creatine Kinase; Cysteine; Disulfides; Enzyme Inhibitors; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Hypochlorous Acid; Methionine; Muscles; Oxidants; Oxidation-Reduction; Rabbits; Sulfhydryl Compounds; Taurine

2006
IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation.
    The Biochemical journal, 2006, May-15, Volume: 396, Issue:1

    Topics: Active Transport, Cell Nucleus; Antioxidants; Cell Membrane Permeability; Chloramines; Glutathione; Glycine; Humans; Hypochlorous Acid; I-kappa B Proteins; Jurkat Cells; Methionine; Neoplasm Proteins; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidants; Oxidation-Reduction; Taurine; Tumor Necrosis Factor-alpha

2006
Effects of biological oxidants on the catalytic activity and structure of group VIA phospholipase A2.
    Biochemistry, 2006, May-23, Volume: 45, Issue:20

    Topics: Amino Acid Sequence; Animals; Catalysis; Cells, Cultured; Chromatography, Liquid; Cysteine; Dithiothreitol; Group VI Phospholipases A2; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Molecular Sequence Data; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptide Hydrolases; Phospholipases A; Phospholipases A2; Spectrometry, Mass, Electrospray Ionization; Spodoptera; Temperature; Time Factors; Tryptophan

2006
Modification of tryptophan and methionine residues is implicated in the oxidative inactivation of surfactant protein B.
    Biochemistry, 2007, May-08, Volume: 46, Issue:18

    Topics: Amino Acid Sequence; Animals; Cattle; Hydrogen Peroxide; Hypochlorous Acid; Iron; Methionine; Molecular Sequence Data; Oxidation-Reduction; Phospholipids; Pulmonary Surfactant-Associated Protein B; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan

2007
Reactive oxidants regulate membrane repolarization and store-operated uptake of calcium by formyl peptide-activated human neutrophils.
    Free radical biology & medicine, 2007, Jun-15, Volume: 42, Issue:12

    Topics: Adenosine Triphosphate; Adult; Calcium; Calcium Channels; Catalase; Chemotactic Factors; Fura-2; Humans; Hydrogen Peroxide; Hypochlorous Acid; Leukocytes, Mononuclear; Manganese; Membrane Potentials; Methionine; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Oxidants; Oxygen Consumption; Peroxidase; Reactive Oxygen Species; Sodium Azide; Superoxide Dismutase; Thapsigargin

2007
Possible mechanisms contributing to oxidative inactivation of activated protein C: molecular dynamics study.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:1

    Topics: Allosteric Regulation; Aspartic Acid; Binding Sites; Computer Simulation; Cyanogen Bromide; Enzyme Activation; Enzyme Stability; Histidine; Humans; Hydrogen Bonding; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Models, Molecular; Oxidants; Oxidation-Reduction; Protein Binding; Protein C; Protein Conformation; Recombinant Proteins

2008
Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin.
    Free radical biology & medicine, 2008, Sep-15, Volume: 45, Issue:6

    Topics: Amino Acid Sequence; Chloramines; Chromatography, High Pressure Liquid; Humans; Hypochlorous Acid; In Vitro Techniques; Methionine; Molecular Sequence Data; Myoglobin; Neutrophil Activation; Neutrophils; Spectrometry, Mass, Electrospray Ionization; Tryptophan

2008
Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13.
    Blood, 2010, Jan-21, Volume: 115, Issue:3

    Topics: ADAM Proteins; ADAMTS13 Protein; Amino Acid Sequence; Catalytic Domain; Cells, Cultured; Humans; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Models, Biological; Neutrophils; Oxidants; Oxidation-Reduction; Peptide Fragments; Protein Multimerization; Protein Processing, Post-Translational; Reactive Oxygen Species; Tyrosine; von Willebrand Factor

2010
Methionine oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Nov-03, Volume: 106, Issue:44

    Topics: Bacterial Proteins; Cell Membrane; Cytoplasm; Escherichia coli; Humans; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Methionine Sulfoxide Reductases; Microbial Viability; Neutrophils; Oxidation-Reduction; Oxidoreductases; Peroxidase; Protein Transport; Signal Transduction

2009
Hypochlorous acid reacts with the N-terminal methionines of proteins to give dehydromethionine, a potential biomarker for neutrophil-induced oxidative stress.
    Biochemistry, 2009, Nov-24, Volume: 48, Issue:46

    Topics: Biomarkers; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Hypochlorous Acid; Magnetic Resonance Spectroscopy; Methionine; Models, Biological; Models, Chemical; Neutrophils; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Peroxidase; Proteins; Spectrometry, Mass, Electrospray Ionization; Sulfones; Thiazoles; Ubiquitin; Uteroglobin

2009
Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid.
    Free radical research, 2010, Volume: 44, Issue:7

    Topics: Amyloid beta-Peptides; Astrocytes; Humans; Hydroxyl Radical; Hypochlorous Acid; Luminescent Measurements; Luminol; Methionine; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Peroxidase

2010
Inhibition of tubulin polymerization by hypochlorous acid and chloramines.
    Free radical biology & medicine, 2011, Apr-15, Volume: 50, Issue:8

    Topics: Animals; Blotting, Western; Brain; Chloramines; Hypochlorous Acid; Methionine; Oxidation-Reduction; Swine; Tubulin

2011
Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region.
    Blood, 2011, Nov-10, Volume: 118, Issue:19

    Topics: ADAM Proteins; ADAMTS13 Protein; Binding Sites; Blood Platelets; Humans; Hypochlorous Acid; In Vitro Techniques; Methionine; Models, Molecular; Oxidation-Reduction; Protein Multimerization; Protein Unfolding; Proteolysis; Shear Strength; Stress, Mechanical; von Willebrand Factor

2011
Methionine oxidation activates a transcription factor in response to oxidative stress.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Jun-04, Volume: 110, Issue:23

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Western; Chromatography, Gel; DNA Mutational Analysis; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Hypochlorous Acid; Immunity, Innate; Iron; Mass Spectrometry; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Oxidation-Reduction; Oxidative Stress; Real-Time Polymerase Chain Reaction; Repressor Proteins; Ultracentrifugation

2013
Tetramers are the activation-competent species of the HOCl-specific transcription factor HypT.
    The Journal of biological chemistry, 2014, Jan-10, Volume: 289, Issue:2

    Topics: Arginine; Blotting, Western; Circular Dichroism; DNA; Escherichia coli; Escherichia coli Proteins; Fluorescence Polarization; Hypochlorous Acid; Kinetics; Methionine; Mutation; Oxidation-Reduction; Protein Binding; Protein Multimerization; Protein Stability; Repressor Proteins; Sodium Chloride; Temperature; Time Factors

2014
Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach.
    Free radical biology & medicine, 2014, Volume: 73

    Topics: Computational Biology; Cysteine; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Oxidants; Oxidation-Reduction; Peptides; Peroxidase

2014
Hypochlorous acid generated by neutrophils inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 proteolytic activity during inflammation.
    The Journal of biological chemistry, 2015, Jan-16, Volume: 290, Issue:3

    Topics: ADAM Proteins; ADAMTS13 Protein; Chromatography, Liquid; Fibrinolysin; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Leukocyte Elastase; Mass Spectrometry; Methionine; Neutrophils; Oxidants; Oxygen; Peroxidase; Protein Structure, Tertiary; Thrombosis; von Willebrand Factor

2015
Repairing oxidized proteins in the bacterial envelope using respiratory chain electrons.
    Nature, 2015, Dec-17, Volume: 528, Issue:7582

    Topics: Bacterial Proteins; Cell Membrane; Chlorine; Electron Transport; Electrons; Gram-Negative Bacteria; Hypochlorous Acid; Methionine; Methionine Sulfoxide Reductases; Periplasm; Reactive Oxygen Species

2015
Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 02-26, Volume: 116, Issue:9

    Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hypochlorous Acid; Methionine; Models, Molecular; Oxidation-Reduction; Protein Conformation; Protein Structure, Tertiary; Repressor Proteins; Salmonella typhimurium; Transcription, Genetic

2019
Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage.
    Free radical biology & medicine, 2022, 08-01, Volume: 188

    Topics: Extracellular Matrix; Humans; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Nitrites; Nitrogen Dioxide; Oxidants; Peroxidase; Tryptophan; Tyrosine

2022