methionine has been researched along with folic acid in 912 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 316 (34.65) | 18.7374 |
| 1990's | 116 (12.72) | 18.2507 |
| 2000's | 223 (24.45) | 29.6817 |
| 2010's | 190 (20.83) | 24.3611 |
| 2020's | 67 (7.35) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Das, KC; Herbert, V | 2 |
| Poirier, LA | 2 |
| Levi, RN; Waxman, S | 1 |
| Rogers, AE | 1 |
| Connor, H; Newton, DJ; Preston, FE; Woods, HF | 1 |
| Erbe, RW; Hoffman, RM | 1 |
| Jacobsen, SJ; Mangum, JH; North, JA; Rao, NA | 1 |
| Benesh, FC; Carl, GF | 1 |
| Canfield, CJ; McCormick, GJ; Smith, CC | 1 |
| Batra, KK; Stokstad, EL; Watson, JE | 1 |
| Billings, RE; Tephly, TR | 1 |
| Chavez, E; Hafez, YS; Kratzer, FH; Vohra, P | 1 |
| Fry, DW; Goldman, ID; White, JC | 1 |
| Cooper, BA | 2 |
| Delk, AS; Rabinowitz, JC | 2 |
| Davidson, GE; Scott, JM; Weir, DG | 1 |
| Rabinowitz, JC | 1 |
| Chiao, F; Stokstad, EL | 1 |
| Shane, B; Stokstad, EL; Watson, JE | 1 |
| Petri, WA; Poirier, LA | 1 |
| Giliberti, P; Pignero, A; Tancredi, F | 1 |
| Chiao, FF; Stokstad, EL | 1 |
| Cornwell, PE; Krumdieck, CL; Leichter, J; Thompson, RW | 1 |
| Hasegawa, A; Suketa, Y; Urakubo, G; Yamamoto, T | 1 |
| Abbakumov, SA; Makolkin, VI; Masliuk, VI; Nedostup, AV; Popova, TA | 1 |
| Hems, R; Krebs, HA | 1 |
| Hems, R; Krebs, HA; Tyler, B | 1 |
| Grzelakowska-Sztabert, B; Landman-Balińska, M | 1 |
| Grzelakowska-Sztabert, B | 1 |
| Mezey, E | 1 |
| Bradley, RJ; Linton, PH; Smythies, JR | 1 |
| Erbe, RE | 1 |
| Luzzati, M | 1 |
| Corcino, JJ; Klipstein, FA | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH | 1 |
| Baldessarini, RJ | 1 |
| Brothers, V; Gerritsen, T; Rowley, BN | 1 |
| Bertino, JR; Cashmore, AR; Chello, PL; Coward, JK; DeAngelis, LM; Parameswaran, KN | 1 |
| Beuhring, KU; Shin, YS; Stokstad, EL | 1 |
| Hanna, LM; Taylor, RT | 1 |
| Cheng, FW; Shane, B; Stokstad, EL | 1 |
| Caboche, M | 1 |
| Hieb, WF; Lu, NC; Stokstad, EL | 1 |
| Spray, GH; Williams, DL | 1 |
| Andersson, A; Brattström, L; Hultberg, B; Israelsson, B; Olsson, A | 1 |
| Cross, DR; James, SJ; Miller, BJ | 1 |
| Poirier, LA; Wainfan, E | 1 |
| Andersson, A; Brattström, L; Hamfelt, A; Hultberg, B; Isaksson, A; Israelsson, B | 1 |
| Allen, RH; Brass, EP; Marcell, PD; Stabler, SP | 1 |
| Lejeune, J | 1 |
| Brattström, L; Hultberg, B; Israelsson, B; Lagerstedt, C; Tengborn, L | 1 |
| Refsum, H; Ueland, PM; Wesenberg, F | 1 |
| Abels, J; Ermens, AA; Guttormsen, AB; Lindemans, J; Refsum, H; Rupreht, J; Spijkers, LJ; Ueland, PM | 1 |
| Pesti, GM; Rowland, GN; Ryu, KS | 1 |
| Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Locniskar, M; Newberne, PM | 1 |
| Maree, KA; Metz, J; van der Westhuyzen, J | 1 |
| Brody, T; Stokstad, EL | 1 |
| Aoyama, K | 1 |
| Iwai, K; Kohashi, M; Takahashi, A | 1 |
| Newberne, PM; Rogers, AE | 1 |
| James, SJ; Yin, L | 1 |
| Catlin, BW | 1 |
| Galivan, J; Johnson, TB; Priest, DG; Rhee, MS | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 4 |
| Cook, RJ; Horne, DW; Wagner, C | 1 |
| Horne, DW | 1 |
| Boss, GR | 2 |
| Chanarin, I; Deacon, R; Lumb, M; Muir, M; Perry, J | 1 |
| Lapin, IP; Ryzhov, IV | 1 |
| Metz, J; van der Westhuyzen, J | 2 |
| Fisler, JS; McKee, R; Sun, S; Swendseid, ME | 1 |
| Davis, RE; Icke, GC; Metz, J; van der Westhuyzen, J | 1 |
| Duffy, TH; Huennekens, FM; Vitols, KS | 1 |
| Bottiglieri, T; Clayton, PT; Hyland, K; Leonard, JV; Perry, J; Smith, I; Wendel, U | 1 |
| Dudman, NP; Robertson, MR; Tyrrell, PA; Wilcken, DE | 1 |
| Brattström, LE; Hultberg, BL; Israelsson, B | 1 |
| Bester, AJ; Beyers, AD; Jaskiewicz, K; van Helden, PD | 1 |
| Karasawa, M; Maekawa, T; Omine, M; Yatabe, H | 1 |
| Galivan, J; Johnson, T; Kesevan, V; McGuire, JJ; Priest, D; Rhee, M | 1 |
| Berlow, S | 1 |
| Eto, I; Krumdieck, CL | 1 |
| Pristoupil, TI; Pristoupilová, K | 1 |
| Shane, B; Stokstad, EL | 2 |
| Matalon, R; Michals, K; Murphy, JV; Thome, LM | 1 |
| Brattström, LE; Hardebo, JE; Hultberg, BL | 1 |
| Dudman, NP; Tyrrell, PA; Wilcken, DE | 1 |
| Corbeel, L; Eeckels, R; Jaeken, J; Van den Berghe, G; Van Tornout, J | 1 |
| Boyd, JN; Graham, ES; Graham, TC; Tennant, BC | 1 |
| Barak, AJ; Beckenhauer, HC; Tuma, DJ | 2 |
| Pagliaro, L | 1 |
| Chanarin, I | 1 |
| Poirier, LA; Whitehead, VM | 1 |
| Gawthorne, JM; Osborne-White, WS; Smith, RM | 1 |
| Gawthorne, JM; Smith, RM | 1 |
| Konttinen, K; Oura, E; Suomalainen, H | 1 |
| Reynolds, EH | 1 |
| Battesti, JP; Thuillier, A | 1 |
| Jaenicke, L; Sauer, H; Wilmanns, W; Wilms, K | 1 |
| Cossins, EA; Lor, KL | 1 |
| Bertino, JR; Nahas, A; Nixon, PF; Slutsky, G | 1 |
| Murray, CL; Rabinowitz, JC; Samuel, CE | 2 |
| Rabinowitz, JC; Samuel, CE | 2 |
| Jungkind, DL; Wood, RC | 1 |
| Dadd, RH | 1 |
| Fassati, M; Pristoupilová, K; Schön, E; Sochman, J; Soucek, J | 1 |
| Boselli, A | 1 |
| Beumer-Jochmans, MP; Godard, C | 1 |
| DeBusk, AG; Rho, HM | 1 |
| Foti, V; Piazza, E; Sindoni, G; Stornello, C | 1 |
| Beaton, JM; Bradley, RJ; Bridgers, WF; McClain, LD; Pegram, GV; Smythies, JR | 1 |
| Hermans, MA; Kitajima, EW; Mundim, MH; Roitman, I | 1 |
| Foster, MA; Guest, JR; Woods, DD | 1 |
| Galloway, E; Kutzbach, C; Stokstad, EL | 1 |
| Daniel, LJ; Griffiths, JM | 1 |
| Hanna, ML; Taylor, RT | 3 |
| Ritari, SJ; Rosales, F; Sakami, W | 1 |
| Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ | 1 |
| Holland, P; Little, C | 1 |
| Stokstad, EL; Vidal, AJ | 1 |
| Batra, KK; Buehring, KU; Stokstad, EL | 2 |
| Erbe, RW; Kamely, D; Littlefield, JW | 1 |
| Clark, BR; Halpern, BC; Halpern, RM; Hardy, DN; Smith, RA | 1 |
| Jaenicke, L; Sauer, H | 1 |
| Monnens, LA; Schretlen, ED; Sengers, RC; Trijbels, JM; van der Zee, SP; Vrenken, JA | 1 |
| Decter, JB; Mansouri, A; Silber, R | 1 |
| Sviatkina, OB; Vel'tishchev, IuE | 1 |
| Zittoun, J; Zittoun, R | 1 |
| Greene, RC; Kung, HF; Spears, C; Weissbach, H; Williams, RD | 1 |
| Mandula, BB; Mosteller, RD | 1 |
| Nair, CP; Noronha, JM | 1 |
| Karlin, R; Levrat, R | 1 |
| Foster, MA; Pattison, JR; Salem, AR | 1 |
| Turner, B; Wilcken, B | 1 |
| Ellegaard, J; Esmann, V | 3 |
| Stokstad, EL; Thenen, SW | 1 |
| Bouveng, R | 1 |
| Howell, JN; Jaenicke, L; Sauer, H | 1 |
| Carson, NA; Ritchie, JW | 1 |
| Bertino, JR; Chello, PL | 1 |
| Arakawa, T; Honda, Y; Narisawa, K | 1 |
| Ordonez, LA; Wurtman, RJ | 1 |
| Brandt, NJ; Hilden, M; Nilsson, IM; Schonheyder, F | 1 |
| Taylor, RT; Weissbach, H | 4 |
| Dickerman, H; Taylor, RT; Weissbach, H | 2 |
| Taylor, RT; Weissbach, H; Whitfield, C | 1 |
| Nishimura, S; Takeishi, K; Ukita, T | 1 |
| Weissbach, H; Whitfield, CD | 1 |
| Gordon, B; Pine, MJ; Sarimo, SS | 1 |
| Viñuela, E | 1 |
| Burton, E; Sakami, W; Selhub, J | 1 |
| Gold, LM; Schweiger, M | 1 |
| Ljungdahl, LG | 1 |
| Jaenicke, L; Rüdiger, H | 2 |
| Steers, EJ; Weissbach, H; Whitfield, CD | 1 |
| Dickerman, HW; Smith, BC | 1 |
| Bertino, JR; Nixon, PF | 2 |
| Corcino, JJ; Herbert, V; Waxman, S | 1 |
| Corcino, J; Herbert, V; Waxman, S | 1 |
| Kerwar, SS; Weissbach, H | 1 |
| Pine, MJ; Sarimo, SS | 1 |
| Rüdiger, H | 1 |
| Dawes, J; Foster, MA | 1 |
| Jaenicke, L | 1 |
| Koch, J; Stokstad, EL; Wang, FK | 1 |
| Mankodi, BS; Rege, DV | 1 |
| Arakawa, T; Narisawa, K; Ohara, K; Tamura, T; Tanno, K | 1 |
| Cossins, EA; Dodd, WA | 2 |
| Hegsted, DM; Vitale, JJ | 2 |
| Doi, RH; Migita, LK | 2 |
| Landureau, JC | 1 |
| D'Ari, L; Rabinowitz, JC; Samuel, CE | 1 |
| Parker, DJ; Wood, HG; Wu, TF | 1 |
| Dickerman, HW | 1 |
| Foster, MA; Salem, AR | 1 |
| Dewey, VC; Kidder, GW | 1 |
| Finkelstein, JD; Freeman, JM; Mudd, SH; Shih, VE; Uhlendorf, BW | 1 |
| Draper, MW; Mangum, JH; North, JA | 1 |
| Gaull, GE | 1 |
| Barness, LA; Morrow, G | 1 |
| Fuller, HL; Keshavarz, K | 1 |
| Brodie, JD; Burke, GT; Mangum, JH | 2 |
| Dalal, FR; Gots, JS; Gots, RE | 1 |
| Dickerman, H; Weissbach, H | 1 |
| Brawerman, G; Eisenstadt, JM; Meyer, R; Schwartz, JH | 1 |
| Spatz, R | 1 |
| Mangum, JH; Murray, BK; North, JA | 1 |
| Wada, Y | 1 |
| Fenichel, GM | 1 |
| Allen, SH; Marston, HR | 1 |
| Bryan, RN; Hayashi, M | 1 |
| Dumont, M; Karlin, R | 1 |
| Foster, MA; Salem, AR; Wilson, RH | 1 |
| Fujii, K; Fukui, S | 1 |
| Levy, H; Morrow, G; Mudd, SH | 1 |
| Hinds, KR; Mudd, SH; Uhlendorf, BW | 1 |
| Goodman, SI; Hammond, KB; Moe, PG; Mudd, SH; Uhlendorf, BW | 1 |
| Bensch, K; Hagberg, B; Hambraeus, L | 1 |
| Gawthorne, JM; Stokstad, EL | 1 |
| Kerwar, SS; McAuslan, B; Spears, C; Weissbach, H | 1 |
| Epshteĭn, IaA; Ustimova, MI | 1 |
| Gross, TS; Lomax, CA; Woods, RA | 1 |
| Jensen, LS; Latshaw, JD | 1 |
| Herbert, V; Kelly, A; Metz, J; Swett, VC; Waxman, S | 1 |
| Carey, MC; Fennelly, JJ; FitzGerald, O | 1 |
| Potty, VH; Tamhane, DV | 1 |
| Carré, IJ; Carson, NA | 1 |
| Honda, Y; Narisawa, K; Ohara, K; Tamura, T; Tanno, K | 1 |
| Parry, TE | 1 |
| Burton, EG; Sakami, W | 1 |
| Karlin, R | 1 |
| Chastain, B; Novelli, GD; Shugart, L | 1 |
| Henderson, TO; McNeill, JJ; Tove, SB | 1 |
| Newberne, PM; Woodard, JC | 1 |
| Daniel, LJ; Lust, G | 1 |
| Babcock, K; Daniel, JW | 1 |
| Shah, E; Stokstad, EL; Webb, RS | 1 |
| Kutzbach, C; Stokstad, EL | 1 |
| Brodie, JD | 1 |
| Guttman, HN | 1 |
| Hegsted, DM; McCombs, HL; Roach, AM | 1 |
| Finkelstein, JD; Mudd, SH | 1 |
| Scott, JM; Weir, DG | 1 |
| Chan, PY; Cossins, EA | 1 |
| Chen, AT; Reidy, JA | 1 |
| Dinn, J; McGing, P; McKenna, B; Molloy, A; Scott, JM; Weir, DG | 1 |
| Smythies, JR | 1 |
| Bokhorov, O; Chotinski, D; Lazareov, I | 1 |
| Reidy, JA | 1 |
| Belousova, AK; Gerasimova, GK; Greshilov, MM; Vorontsov, IN | 2 |
| Billings, RE; Noker, PE; Tephly, TR | 1 |
| Bertino, JR; Cashmore, AR; Dreyer, RN; Moroson, BA; Scanlon, KJ | 1 |
| Chanarin, I; Hewlett, AM; Lewis, JD; Lumb, M; Nunn, JF; Skacel, PO | 1 |
| Allen, RJ; Coulter, DL; DiMauro, S; Papadimitriou, A; Rothenberg, SP | 1 |
| Bourdel, G; Goubern, M; Hitier, Y; N'Diaye, F; Poiter de Courcy, G | 1 |
| Brody, T; Chan, MM; Stokstad, EL; Watson, JE | 1 |
| Fujii, K; Huennekens, FM; Nagasaki, T | 1 |
| Henderson, JF | 1 |
| Cooper, BA; Harpey, JP; Lafourcade, J; Le Moël, G; Rosenblatt, DS; Roy, C | 1 |
| Nauss, KM; Newberne, PM | 1 |
| Wickramasinghe, SN | 1 |
| Brody, T; Stokstad, EL; Watson, JE | 1 |
| Hoffmann, H; Kirchner, E | 1 |
| Black, KA; Eells, JT; Makar, AB; Tedford, CE; Tephly, TR | 1 |
| Fernandes-Costa, F; Metz, J; van der Westhuyzen, J | 1 |
| Farnworth, ER; Hill, DC | 1 |
| Benevenga, NJ; Berlow, S; Smolin, LA | 1 |
| Bujoli, J; Potier de Courcy, G | 1 |
| McGing, PG; Scott, JM | 1 |
| Chan, MM; Stokstad, EL | 1 |
| Akesson, B; Fehling, C; Jägerstad, M | 1 |
| Blakely, R; Coakley, G; Spector, R | 1 |
| Edwards, HM; Eitenmiller, RR; Pesti, GM; Roberson, KD; Ryu, KS | 1 |
| Alonso-Aperte, E; Alvarez, L; Caballería, J; Deulofeu, R; Gassó, M; Mato, JM; Rodés, J; Rubio, M; Varela-Moreiras, G | 1 |
| Becker, PJ; Delport, R; Potgieter, H; Ubbink, JB; van der Merwe, A; Vermaak, WJ | 1 |
| Boujet, C; Buist, N; Davidson-Mundt, A; Hudgins, L; Levy, HL; Mudd, SH; Nagao, M; Oyanagi, K; Tangerman, A; Wilson, WG | 1 |
| Ascherio, A; Colditz, GA; Giovannucci, E; Rimm, EB; Stampfer, MJ; Willett, WC | 1 |
| Christman, JK; Cravo, ML; Fleet, JC; Kim, YI; Mason, JB; Ordovas, J; Salomon, RN; Selhub, J; Smith, D | 1 |
| Atkinson, IJ; Cossins, EA; Nargang, FE | 1 |
| Blom, HJ; Boers, GH; Franken, DG; Jakobs, C; Kluft, C; Rauwerda, JA; Stehouwert, CD; Van den Berg, M; Van Kamp, GJ | 1 |
| Henning, SM; Jacob, RA; Pianalto, FS; Swendseid, ME; Zhang, JZ | 1 |
| Boers, GH; Janssen, MJ; Stehouwer, CD; van den Berg, M | 1 |
| Benkovic, SJ; Marolewski, A; Nagy, PL; Zalkin, H | 1 |
| Wood, RC | 1 |
| Fiskerstrand, T; Guttormsen, AB; Refsum, HM; Schneede, J; Ueland, PM | 1 |
| Baik, MG; Choi, CB; Keller, WL; Park, CS | 1 |
| Blom, HJ; Boers, GH; Borm, GF; Eskes, TK; Finkelstein, JD; Steegers-Theunissen, RP; Thomas, CM; Trijbels, FJ; Wouters, MG | 1 |
| Henning, SM; Jacob, RA; Swendseid, ME; Wu, MM | 1 |
| Boers, GH | 2 |
| Christensen, B; Fiskerstrand, T; Refsum, H; Tysnes, OB; Ueland, PM | 1 |
| Paszewski, A | 1 |
| Basso, J; Herrington, MB | 1 |
| Eskes, TK; Hollanders, HM; Peereboom-Stegeman, JH; Steegers, EA; Steegers-Theunissen, RP; Thomas, CM; Trijbels, FJ | 1 |
| Christensen, B; Ueland, PM | 1 |
| Bergmark, C; de Faire, U; Mansoor, MA; Svardal, AM; Swedenborg, J; Ueland, PM | 1 |
| Hsu, JC; Kim, JS; Lin, BF; Lowe, KE; Osborne, CB; Shane, B | 1 |
| Essien, FB; Wannberg, SL | 1 |
| Cooper, BA; Dilling, LA; Haworth, JC; Lue-Shing, H; Rosenblatt, DS; Seargeant, LE; Surtees, RA | 1 |
| Abileah, S; Christman, JK; Dizik, M; Sheikhnejad, G; Wainfan, E | 1 |
| Colditz, GA; Giovannucci, E; Rimm, EB; Rosner, BA; Speizer, FE; Stampfer, MJ; Trichopoulos, D; Willett, WC | 1 |
| Bierdrager, E; Rauwerda, JA; Stehouwer, CD; van den Berg, M | 1 |
| Guttormsen, AB; Refsum, H; Schneede, J; Ueland, PM | 1 |
| Aukrust, P; Berge, RK; Frøland, SS; Müller, F; Svardal, AM; Ueland, PM | 1 |
| Colditz, GA; Frazier, AL; Willett, WC | 1 |
| Schalinske, KL; Steele, RD | 1 |
| Allen, RH; Buring, JE; Gaziano, JM; Hennekens, CH; Kok, FJ; Reynolds, RD; Stabler, SP; Stampfer, MJ; Verhoef, P; Willett, WC | 1 |
| Allen, RH; Chandler, CJ; Halsted, CH; James, SJ; Muskhelishvili, L; Poirier, L; Stabler, SP; Villanueva, J | 1 |
| Kim, SH; Moon, YS; Park, CS | 1 |
| Chen, J; Colditz, GA; Giovannucci, E; Hunter, DJ; Kelsey, K; Rimm, EB; Spiegelman, D; Stampfer, MJ; Willett, WC | 1 |
| Henning, SM; Swendseid, ME | 1 |
| Dennis, VW; Robinson, K | 1 |
| Amendt, K; Diehm, C; Hsu, E; Stammler, F; Stockinger, K | 1 |
| Anderson, A; Daskalakis, IG; Lean, ME; Levene, MI; Lucock, MD; Schorah, CJ; Wild, J | 1 |
| Gottfries, CG; Regland, B; Smythies, JR | 1 |
| Allen, WP | 1 |
| Crowe, SF; Ross, CK | 1 |
| Crooks, R; Dudman, N; Finucane, P; Fryer, J; Guo, XW; Nair, B; Silberberg, J; Wlodarczyk, J; Xie, LJ | 1 |
| Matthews, JH | 1 |
| Edwards, SL; Ma, KN; Potter, JD; Schaffer, D; Slattery, ML | 1 |
| Blom, HJ; Kluijtmans, LA; Kok, FJ; Kruyssen, DA; Refsum, H; Ueland, PM; Verhoef, P | 1 |
| Guttormsen, AB; Refsum, H; Svarstad, E; Ueland, PM | 1 |
| Huang, EY; Mohler, AM; Rohlman, CE | 1 |
| Boiocchi, M; Corona, G; Donada, C; Fabris, M; Toffoli, G; Viel, A; Zarrelli, A | 1 |
| Bianchi, LA; Bostom, AG; Gohh, RY; Hopkins-Garcia, BJ; Jacques, PF; Nadeau, MR; Rosenberg, IH; Selhub, J; Tsai, MY | 1 |
| Drabløs, PA; Hervig, T; Hetland, O; Kristensen, O; Mansoor, MA; Osland, A; Stakkestad, JA; Woie, L | 1 |
| Beaulieu, AJ; Bostom, AG; Gohh, RY; Hume, AL; Jacques, PF; Nadeau, MR; Rosenberg, IH; Selhub, J | 1 |
| Schaffer, DM; Shaw, GM; Velie, EM | 1 |
| Aubard, Y; Baudet, JH; Chinchilla, AM; Piver, P | 1 |
| Balińska, M; Lewandowska, I; Paszewski, A | 1 |
| Adão, M; Azinheira, J; Bordalo-Sá, AL; Correia, JM; Luís, AS; Pina, JE; Reis, HP; Reis, RP; Santos, L; Tavares, J | 2 |
| Gérard, M; Ogier de Baulny, H; Saudubray, JM; Zittoun, J | 1 |
| Allen, RH; Lindenbaum, J; Stabler, SP | 1 |
| Eskes, TK | 4 |
| Copp, AJ; Fleming, A | 1 |
| Hamano, H; Takizawa, S | 1 |
| Boddie, AM; Dembure, PP; Elsas, LJ; Fisher, AJ; Macmahon, W; Saxe, D; Steen, MT; Sullivan, KM | 1 |
| Brouwer, DA; Muskiet, FA; Reijngoud, DJ; van Doormaal, JJ; Welten, HT | 1 |
| Hishida, R; Nau, H | 1 |
| de Vries, JI; Dekker, GA; Jakobs, C; Leeda, M; Riyazi, N; van Geijn, HP | 1 |
| Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL | 1 |
| Chen, J; Hunter, DJ; Kelsey, K; Rimm, EB; Stampfer, MJ; Verhoef, P; Willett, WC | 1 |
| Le Leu, RK; McIntosh, GH; Young, GP | 1 |
| Colditz, GA; Fuchs, C; Giovannucci, E; Hunter, DJ; Rosner, BA; Speizer, FE; Stampfer, MJ; Willett, WC | 1 |
| Cole, DE; Daly, PA; Evrovski, J; Langman, LJ; Miner, SE; Ross, HJ; Wong, PY | 1 |
| Chen, J; Giovannucci, E; Hankinson, SE; Hunter, DJ; Kelsey, KT; Ma, J; Spiegelman, D; Willett, WC | 1 |
| Bester, MJ; Blom, HJ; Christianson, A; Delport, R; Potgieter, H; Ubbink, JB; Van Allen, MI; van der Merwe, A; Venter, PA; Vermaak, WJ | 1 |
| Imaizumi, T; Matsuoka, H; Miyazaki, H; Okuda, S; Ueda, S; Usui, M | 1 |
| Cattaneo, M | 1 |
| Chen, J; Giovannucci, EL; Hunter, DJ | 1 |
| Achón, M; Alonso-Aperte, E; Pérez-Miguelsanz, J; Ubeda, N; Varela-Moreiras, G | 1 |
| de Meer, K; Donker, AJ; Janssen, MJ; Stehouwer, CD; van Guldener, C | 1 |
| Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
| Maciejewska, M; Prusiewicz-Witaszek, U | 1 |
| Banga, JD; Biesma, DH; Duran, M; Haas, FJ; Meuwissen, OJ; van der Griend, R | 1 |
| Alders, D; de Jong, SC; Jakobs, C; Kostense, PJ; Pals, G; Rauwerda, JA; Stehouwer, CD; van den Berg, M | 1 |
| Odekerken, DA; Rakic, M; Sijbrands, EJ; Silberbusch, J; Slaats, EH; Smulders, YM; Stehouwer, CD; Treskes, M | 1 |
| Aarnoudse, JG; Lubbers, MF; van Doormaal, JJ | 1 |
| Anderstam, B; Bàràny, P; Bergström, J; Divino Filho, JC; Lindholm, B; Suliman, ME | 1 |
| Leppert, M; Potter, JD; Samowitz, W; Schaffer, D; Slattery, ML | 1 |
| Boers, GH; de Jong, SC; Devillé, W; Jakobs, C; Pals, G; Rauwerda, JA; Stehouwer, CD; van den Berg, M | 1 |
| Gravel, RA; Leclerc, D; Rosenblatt, DS; Wilson, A | 1 |
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| Best, J; Golubitsky, M; Nijhout, HF; Reed, M; Stewart, I | 1 |
| Albanes, D; Arslan, AA; Blot, WJ; Bolton, JH; Brennan, P; Buring, JE; Butler, LM; Cai, Q; Caporaso, NE; Ericson, U; Fanidi, A; Freedman, ND; Gao, YT; Gaziano, JM; Giles, GG; Giovannucci, E; Grankvist, K; Haiman, CA; Han, J; Hodge, AM; Johansson, M; Koh, WP; Krokstad, S; Lan, Q; Langhammer, A; Le Marchand, L; Lee, IM; Li, H; Manjer, J; McCullough, ML; Midttun, Ø; Muller, DC; Næss, M; Pettinger, M; Prentice, R; Purdue, M; Relton, C; Sesso, HD; Severi, G; Shu, XO; Smith-Warner, SA; Stampfer, MJ; Stevens, VL; Thomsen, CA; Ueland, PM; Ulvik, A; Visvanathan, K; Wang, R; Weinstein, SJ; Wilkens, LR; Wu, J; Xiang, YB; Yuan, JM; Zeleniuch-Jacquotte, A; Zhang, X; Zheng, W; Ziegler, RG | 1 |
| Bischof, RJ; Clifton, VL; Gatford, KL; Giles, LC; Heinemann, GK; Hunter, DS; Kind, KL; Lien, YC; Liu, H; Lu, W; Owens, JA; Rabinowitz, JD; Simmons, RA; Wooldridge, AL | 1 |
| Calvani, E; Chen, Q; Copp, AJ; Greene, NDE; Gross, SS; Leung, KY; Pai, YJ; Ralser, M; Santos, C; Savery, D; Sudiwala, S | 1 |
| Koutmos, M; Yamada, K | 1 |
| Adam, AC; Bock, C; Dahl, JA; Espe, M; Fernandes, JMO; Jakt, LM; Klughammer, J; Skjærven, KH | 1 |
| Attia, JR; Butler, T; Chan, EC; Collins, CE; Evans, TJ; Hure, AJ; Mossman, D; Smith, R; Smith, T; Taylor, RM; Wong-Brown, MW | 1 |
| Bainbridge, S; Fontaine-Bisson, B; McGee, M | 1 |
| Ray, D; Richardson, BC; Strickland, FM | 1 |
| Bushel, P; Chandel, N; Grenet, D; Li, J; Lozoya, OA; Martinez-Reyes, I; Santos, JH; Wang, T; Woychik, RP | 1 |
| Bennett, CD; Bhat, DS; Gruca, LL; Kalhan, SC; Katre, P; Kurpad, AV; Yajnik, CS | 1 |
| Anderson, KE; Fan, H; Hoyt, ML; Marley, AR; Zhang, J | 1 |
| Bartlett, RK; Bertolo, RF; Brunton, JA; Harding, SV; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Kalani, A; Lominadze, D; Muradashvili, N; Nuru, M; Tyagi, N | 1 |
| Che, L; Fang, Z; Feng, B; Jiang, X; Jin, C; Li, J; Lin, Y; Xu, S; Xuan, Y; Zhao, Y; Zhou, P | 1 |
| Brassington, AH; Clare, CE; Kwong, WY; Sinclair, KD | 1 |
| Chiang, AJ; Gugiu, GB; Hu, W; Kalkum, M; Morra, CN; Röth, D; Versalovic, J | 1 |
| Fuchida, T; Goto, T; Ishii, D; Matsuzawa, D; Sahara, Y; Shimizu, E; Sutoh, C | 1 |
| Aldrich, CC; Baughn, AD; Bauman, AA; Cole, MS; Howe, MD; Kordus, SL; Minato, Y | 1 |
| Dolenc, MS; Geršak, K; Grželj, J; Mlinarič-Raščan, I; Vidmar, M | 1 |
| Collins, CE; Evans, TJ; Hure, AJ; Smith, R; Taylor, RM | 1 |
| Liao, LM; Lu, J; Michels, KA; Pfeiffer, RM; Trabert, B | 1 |
| Cantley, LC; Zheng, Y | 1 |
| Cherrington, NJ; Hardwick, RN; Lake, AD; Leamon, CP; Low, PS | 1 |
| Crider, KS; Mitchell, AA; Parker, SE; Petersen, JM; Tinker, SC; Werler, MM | 1 |
| Chorąży, M; Czarnowska, A; Gościk, J; Kapica-Topczewska, K; Kochanowicz, J; Krętowski, AJ; Kułakowska, A; Posmyk, R; Wawrusiewicz-Kurylonek, N; Więsik, M | 1 |
| Belardo, A; Gevi, F; Zolla, L | 1 |
| Goyal, A; Gupta, JK; Narayan Yadav, H; Qureshi, SS | 1 |
| Alberto, JM; Battaglia-Hsu, SF; Chéry, C; Gauchotte, G; Guéant, JL; Hergalant, S; Namour, F; Quéré, M; Rouyer, P; Zgheib, R | 1 |
| Dai, Z; Gao, X; Locasale, JW; Sanderson, SM | 1 |
| Ares-Pensado, B; Castro, A; Fernandez-Pajarin, G; Rivero-de-Aguilar, A; Sesar, A | 1 |
| Chmurzynska, A; Martínez, JA; Milagro, FI; Muzsik, A; Radziejewska, A | 1 |
| Danchin, A; Sekowska, A; You, C | 1 |
| Ampong, I; Eid, N; Griffiths, HR; Morgan, HL; Rouillon, C; Watkins, AJ | 1 |
| Jafarpour, F; Jozi, M; Karbalaie, K; Moradi, R; Nasr-Esfahani, MH; Zadegan, FG | 1 |
| Bernard, JK; Duplessis, M; Girard, CL; McFadden, JW; Tao, S; White, HM; Zhou, Z | 1 |
| Antwi, SO; Campbell, PT; Liao, LM; McGlynn, KA; Norez, DA; Patel, T; Petrick, JL; Roberts, LR; Stevens, VL | 1 |
| Guéant, JL; Hsu, SB; Namour, F; Oussalah, A; Siblini, Y; Zgheib, R | 1 |
| Bergamini, C; Capelli, I; Cappuccilli, M; Cianciolo, G; Conte, D; Donati, G; Giacomelli, FA; La Manna, G; Natali, T | 1 |
| George, AK; Homme, RP; Jovanovic, M; Singh, M; Stanisic, D; Tyagi, N; Tyagi, SC | 1 |
| Bojarski, B; Lis, MW; Tombarkiewicz, B; Trzeciak, K | 1 |
| Doskey, CM; Fader, KA; Fling, RR; Nault, R; Zacharewski, TR | 1 |
| Aleliunas, RE; Bernatchez, P; Boonpattrawong, NP; Devlin, AM; Golbidi, S; Laher, I; Miller, JW; Tai, DC | 1 |
| Elango, R | 1 |
| Mao, QQ; Wei, DH | 1 |
| Bokkers, BGH; de Leeuw, VC; Piersma, AH; van Nieuwland, M | 1 |
| Dotsenko, O; Shtofel, D | 1 |
| Cai, S; Chen, M; Qiao, S; Quan, S; Wang, G; Wang, Y; Yang, G; Ye, Q; Yu, H; Zeng, X | 1 |
| Bouvier, D; Brailova, M; Minet-Quinard, R; Regnier, A; Sapin, V; Szymanowski, M | 1 |
| Jové, M; Maldonado, J; Martín-Masot, R; Mota-Martorell, N; Nestares, T; Pamplona, R | 1 |
| Jiang, H; Maclean, KN; Mclagan, BM; Phinney, WN; Roede, JR; Stabler, SP | 1 |
| Chen, Y; Du, Y; Fu, J; Huang, G; Jin, M; Li, W; Lin, H; Liu, H; Liu, Q; Ma, F; Sun, C; Wang, G; Yan, J; Zhang, M; Zhu, Y | 1 |
| Arkin, AP; Deutschbauer, AM; Price, MN | 1 |
| Dank, M; Forika, G; Kiss, E; Krenacs, T; Mohacsi, R; Nemeth, Z | 1 |
| Aarsand, AK; Aguilera, P; Brunet, M; Deulofeu, R; García-Villoria, J; Gómez-Gómez, À; Pozo, OJ; Sandberg, S; To-Figueras, J; Wijngaard, R | 1 |
| Abdel-Hamied, E; Alharthi, AS; Ballou, MA; Coleman, DN; Corrêa, MN; Dai, H; Liang, Y; Loor, JJ; Lopes, MG; Lopreiato, V; Socha, MT; Trevisi, E | 1 |
| Agudo, A; Ardanaz, E; Bakker, MF; Biessy, C; Casagrande, C; Chiodini, P; Chirlaque López, MD; Clasen, J; De Bacquer, D; Ericson, U; Ferrari, P; Fortner, RT; Godderis, L; Gunter, MJ; Gylling, B; Halkjær, J; Heath, AK; Huybrechts, I; Karlsson, T; Katzke, V; Manjer, J; Masala, G; Muller, D; Nicolas, G; Overvad, K; Pala, V; Papadimitriou, N; Sacerdote, C; Sánchez, MJ; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Van Herck, K; Van Puyvelde, H; Weiderpass, E | 1 |
| Annibal, A; Antebi, A; Auler, MMK; Grönke, S; Latza, C; Partridge, L; Schonewolff, MF; Tam, H; Tharyan, RG | 1 |
| Adam, AC; Espe, M; Fernandes, JMO; Saito, T; Skjærven, KH; Vikeså, V; Whatmore, P | 1 |
| Chaumette, B; Frajerman, A; Kebir, O; Scoriels, L | 1 |
| Eshak, ES; Inoue, M; Iso, H; Iwasaki, M; Khairan, P; Kitamura, T; Sawada, N; Shimazu, T; Sobue, T; Tsugane, S; Yamaji, T; Zha, L | 1 |
| Ghergurovich, JM; Rabinowitz, JD; Ryseck, RP; Wang, JZ; Wang, L; Xu, X; Yang, L | 1 |
| Matsha, TE; Raghubeer, S | 1 |
| Desai, K; Shinde, V | 1 |
| Ansari, S; Kumar, A; Kumar, S; Malakar, D; Malik, H; Saini, S; Sharma, V; Thakur, A | 1 |
| Korimerla, N; Wahl, DR | 1 |
| Chang, HJ; Kim, J; Lee, J; Oh, JH; Shin, A; Sohn, DK | 1 |
| Fustin, JM | 1 |
| Nagalakshmi, D; Rajkumar, U; Raju, MVLN; Rao, SVR; Srilatha, T | 1 |
| Jakubowski, H; Perła-Kaján, J | 1 |
| Chen, ZJ; Lei, MZ; Lei, QY; Li, JT; Li, KY; Lu, HJ; Lv, L; Qu, J; Su, Y; Wang, J; Wang, L; Yang, H; Yin, M; Zhang, L; Zhu, WP; Zhu, WY | 1 |
| Fang, AP; He, TT; Liu, XZ; Liu, ZY; Luo, Y; Wusiman, M; Xiao, HW; Yishake, D; Zhu, HL | 1 |
| Abdul Ghani, SAB; Arul, K; Bee, GGB; Cheah, CC; Chow, PKH; Cook, SA; Lim, TR; Pei, HJ; Sandireddy, R; Shekeran, SG; Singh, BK; Singh, MK; Sinha, RA; Suzuki, A; Tikno, K; Tripathi, M; Wang, J; Widjaja, A; Wong, KA; Xiao, RP; Yen, PM; Zhang, X; Zhou, J | 1 |
| Balwani, M; Fanelli, MJ; Gouya, L; Longo, N; Petrides, PE; Phillips, J; Plutzky, J; Rhyee, S; Sardh, E; Sweetser, MT; Ventura, P | 1 |
| Fishchuk, L; Gorovenko, N; Rossokha, Z; Yeroshkina, K | 1 |
| Beltrán, LJ; Bulleid, NJ; Johnstone, IL; Page, AP; Tjahjono, E; Winter, AD | 1 |
| Alvarez, JA; Cui, X; Ramakrishnan, U; Schoen, MS; Singh, RH; Ziegler, TR | 1 |
| Ansari, S; Devi, P; Jamwal, S; Kumar, A; Malakar, D; Saini, S; Sehrawat, P; Thakur, A | 1 |
| Asad, Y; Bhalay, G; Donovan, A; Gaborik, Z; Gowan, S; Kis, E; Naseem, A; Pal, A; Raynaud, F; Temesszentandrási-Ambrus, C | 1 |
| Abbas, AM; Alenazy, FO; Alhassan, HH; Davuljigari, CB; Elderdery, AY; Elkhalifa, AME; Mills, J; Shalabi, MG; Tebein, EM | 1 |
| Bo, Y; Cao, Y; Dou, W; Duan, D; Fu, W; Liu, Y; Lyu, Q; Ma, S; Zeng, F; Zhao, X | 1 |
| Bao, W; Cheng, TD; Fowke, JH; Johnson, KC; Liang, X; Liu, B; Mozhui, K; Saquib, N; Sen, S; Shadyab, AH; Snetselaar, LG; Sun, Y; Wallace, RB | 1 |
| Annaful, VT; Annan, RA; Apprey, C; Asamoah-Boakye, O | 1 |
| Fan, G; Ji, W; Li, S; Ma, X; Qin, H; Wang, Y; Wang, Z; Yang, X | 1 |
| Caton, JS; Crouse, MS; Cushman, RA; Dahlen, CR; Freetly, HC; King, LE; Lee, RT; Lindholm-Perry, AK; Neville, BW; Oliver, WT; Reynolds, LP; Syring, JG; Ward, AK | 1 |
| Bekdash, RA | 1 |
| Guyader, J; Jiang, Q; Loor, JJ; Pan, YX; Sherlock, DN; Zhang, H | 1 |
| Andres, C; Bitar, T; Hleihel, W; Roufael, M; Sacre, Y | 1 |
| Borowicz, PP; Caton, JS; Crouse, MS; Dahlen, CR; McLean, KJ; Neville, BW; Neville, TL; Reynolds, LP; Syring, JG; Ward, AK | 1 |
| Cui, W; Fang, F; Han, X; Liu, Y | 1 |
| Ando, N; Burnim, A; Wang, H; Watkins, MB | 1 |
| Antonova, IV; Kozubenko, OV; Turchaninov, DV; Vilms, EA | 1 |
| Chen, K; Gong, J; Liu, F; Peng, Y; Qiao, Y; Si, C; Song, F; Wang, P; Wang, X; Zhou, H | 1 |
| Carmichael, SL; Darling, AM; Desrosiers, TA; Nestoridi, E; Parker, SE; Petersen, JM; Politis, MD; Shaw, GM; Smith-Webb, RS; Werler, MM; Yazdy, MM | 1 |
| Mangoni, AA; Zinellu, A | 1 |
| Clément, A; Clément, P; Menezo, YJR; Viot, G | 1 |
| Koutmos, M; Mendoza, J; Purchal, M; Yamada, K | 1 |
| Gu, J; Lei, C; Zhang, M | 1 |
131 review(s) available for methionine and folic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The role of vitamin B12 and folic acid in hemato- and other cell-poiesis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bacteria; Coenzymes; DNA; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Glutamates; Hematopoiesis; Humans; Megaloblasts; Methionine; Methylmalonyl-CoA Mutase; Neurologic Manifestations; Purines; Pyrimidines; Ribonucleotide Reductases; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1976 |
Methyl biogenesis.
Topics: Folic Acid; Homocysteine; Humans; Leucovorin; Mental Disorders; Methionine; Methionine Adenosyltransferase; Methylation; S-Adenosylmethionine; Tetrahydrofolates | 1978 |
Megaloblastic anaemia and disorders affecting utilisation of vitamin B12 and folate in childhood.
Topics: Adolescent; Adult; Anemia, Hemolytic; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Pernicious; Biological Transport; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Female; Folic Acid; Folic Acid Deficiency; Homocystinuria; Humans; Infant; Intrinsic Factor; Malabsorption Syndromes; Male; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Orotic Acid; Phenylketonurias; Tetrahydrofolate Dehydrogenase; Transcobalamins; Vitamin B 12 | 1976 |
Folic acid metabolism in vitamin B12 deficiency.
Topics: Animals; Biological Transport; Folic Acid; Folic Acid Deficiency; Glutamates; Homocysteine; Humans; Liver; Methionine; Methyltransferases; Peptide Biosynthesis; Rats; Sheep; Tetrahydrofolates; Vitamin B 12 Deficiency | 1975 |
Inborn errors of folate metabolism (first of two parts).
Topics: Adult; Animals; Bone Marrow; Bone Marrow Cells; DNA; Fibroblasts; Folic Acid; Folic Acid Deficiency; Humans; Liver; Metabolism, Inborn Errors; Methionine; Methyltransferases; Rats; Skin; Tetrahydrofolate Dehydrogenase; Vitamin B 12; Vitamin B 12 Deficiency | 1975 |
[The pathogenesis of mental retardation in trisomy 21].
Topics: Amyloid beta-Protein Precursor; Biopterins; Brain; Carbonic Acid; Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Guanosine; Humans; Leucovorin; Mercaptopurine; Methionine; Neurons; Phosphofructokinase-1; Purines; Pyrimidines; S100 Proteins; Superoxide Dismutase; Thyroid Gland; Thyroxine | 1991 |
Roles of micronutrients in cancer prevention: recent evidence from the laboratory.
Topics: Animals; Ascorbic Acid; Choline; Female; Folic Acid; Methionine; Mice; Minerals; Neoplasms, Experimental; Rats; Selenium; Vitamin A; Vitamins; Zinc | 1990 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Cobalamin-folate interrelations.
Topics: Anemia, Megaloblastic; Animals; Central Nervous System Diseases; Coenzymes; Folic Acid; Folic Acid Deficiency; Formates; Humans; Methionine; Models, Biological; Tetrahydrofolates; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1989 |
Cobalamin-folate interrelations: a critical review.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Central Nervous System; Deoxyuridine; Disease Models, Animal; Drug Interactions; Enzyme Activation; Folic Acid; Folic Acid Deficiency; Histidine; Humans; Liver; Methionine; Methylmalonyl-CoA Mutase; Nitrous Oxide; Oxidation-Reduction; Pteroylpolyglutamic Acids; Purines; Serine; Tetrahydrofolates; Thymidylate Synthase; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
[Endogenous convulsants (review)].
Topics: Amino Acids; Animals; Carbolines; Cats; Cerebral Cortex; Convulsants; Cysteic Acid; Cysteine; Disease Models, Animal; Dogs; Estrogens; Folic Acid; Homocysteine; Kynurenine; Methionine; Mice; Neurotransmitter Agents; Prostaglandins; Pyridoxal Phosphate; Quinolinic Acid; Quinolinic Acids; Rats; Seizures; Spinal Cord | 1986 |
The fruit bat as an experimental model of the neuropathy of cobalamin deficiency.
Topics: Animals; Chiroptera; Disease Models, Animal; Fatty Acids; Folic Acid; Methionine; Nervous System Diseases; Neurotransmitter Agents; Vitamin B 12 Deficiency | 1987 |
Folic acid metabolism and its disruption by pharmacologic agents.
Topics: Folic Acid; Folic Acid Antagonists; Forecasting; Methionine; Purines; Serine; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 1987 |
Vitamin B12-folate interrelationships.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bone Marrow; Folic Acid; Folic Acid Deficiency; Formates; Formiminoglutamic Acid; Histidine; Homeostasis; Humans; Liver; Megaloblasts; Methionine; Methylation; Nitrous Oxide; Peptide Synthases; Pteroylpolyglutamic Acids; Purines; Serine; Thymidine Monophosphate; Thymidylate Synthase; Thyroid Gland; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
Epilepsy and schizophrenia: relationship and biochemistry.
Topics: Anemia, Macrocytic; Anticonvulsants; Electroconvulsive Therapy; Electroencephalography; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Mental Disorders; Methionine; Phenethylamines; Phenothiazines; Schizophrenia; Vitamin B 12 | 1968 |
Insect nutrition: current developments and metabolic implications.
Topics: Amino Acids; Animals; Aphids; Ascorbic Acid; Choline; Coleoptera; Cystine; DNA; Drosophila melanogaster; Fatty Acids; Folic Acid; Glycine; Insecta; Lepidoptera; Methionine; Minerals; Nutritional Physiological Phenomena; Proline; RNA; Sterols; Tyrosine; Urea; Vitamin B 12; Vitamin E | 1973 |
[Hereditary anomalies of methionine metabolism in children].
Topics: Age Factors; Child; Flatfoot; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Intellectual Disability; Kyphosis; Marfan Syndrome; Metabolism, Inborn Errors; Methionine; Scoliosis | 1972 |
Folate metabolism.
Topics: Anemia, Sideroblastic; Coenzymes; DNA; FIGLU Test; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Food Analysis; Humans; Intestinal Absorption; Intestine, Small; Liver; Metabolic Clearance Rate; Methionine; Nutritional Requirements; Purines; Tetrahydrofolates; Thymine | 1972 |
Total synthesis of acetate from CO2 by heterotrophic bacteria.
Topics: Acetates; Adenosine Triphosphate; Bacteria; Carbon Dioxide; Citric Acid Cycle; Clostridium; Folic Acid; Formates; Intrinsic Factor; Methane; Methionine; Peptococcus; Vitamin B 12 | 1969 |
Interrelationships of vitamin B12 and folate in man.
Topics: Anemia, Macrocytic; Animals; Folic Acid; Folic Acid Deficiency; Humans; Liver; Methionine; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Drugs, toxins and dietary amino acids affecting vitamin B12 or folic acid absorption or utilization.
Topics: Amino Acids; Anemia, Macrocytic; Contraceptives, Oral; Diet; DNA; Ethanol; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Glycine; Homocysteine; Humans; Malabsorption Syndromes; Methionine; Pharmacology; Serine; Toxins, Biological; Vitamin B 12 | 1970 |
Aggravation or initiation of megaloblastosis by amino acids in the diet.
Topics: Amino Acids; Anemia, Pernicious; Cell Nucleus; Diet; DNA; Erythrocytes; Folic Acid; Folic Acid Deficiency; Glycine; Hematologic Diseases; Homocystine; Humans; Methionine; Polycythemia; Pyridoxine; Serine; Tetrahydrofolate Dehydrogenase; Thymine; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Roles of vitamin B 12 and folic acid in methionine synthesis.
Topics: Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine; Transferases; Vitamin B 12 | 1970 |
The role of folate coenzymes in the initiation of protein synthesis.
Topics: Amino Acyl-tRNA Synthetases; Animals; Chromatography, Gel; Coenzymes; Cytoplasm; Enterococcus faecalis; Escherichia coli; Folic Acid; Formates; Guinea Pigs; Methionine; Methyltransferases; Organoids; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Protein Binding; Rats; RNA, Bacterial; RNA, Transfer; Structure-Activity Relationship; Transfer RNA Aminoacylation | 1971 |
Have the pteroylpolyglutamates a regulatory function?
Topics: Animals; Folic Acid; Methionine; Pteroylpolyglutamic Acids; Structure-Activity Relationship; Tetrahydrofolates | 1983 |
The interrelationships among folate, vitamin B12, and methionine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; DNA; Drug Interactions; Folic Acid; Formates; Histidine; Humans; Megaloblasts; Methionine; Nitrous Oxide; Peptide Synthases; Pteroylpolyglutamic Acids; Purines; Serine; Tetrahydrofolates; Thymidine Monophosphate; Thyroid Gland; Vitamin B 12 | 1983 |
Inhibition of microbial growth by naturally-occurring purine bases and ribonucleosides.
Topics: Bacteria; Culture Media; DNA; Folic Acid; Folic Acid Antagonists; Glycine; Histidine; Methionine; Nutritional Physiological Phenomena; Purine Nucleosides; Purines; Pyrimidines; Succinates; Sulfonamides; Thiamine; Thymine | 1980 |
Effects of dietary folate, vitamin B12 and methionine/choline deficiency on immune function.
Topics: Animals; Antibody Formation; Choline Deficiency; Deoxyuridine; Drug Interactions; Folic Acid; Folic Acid Deficiency; Humans; Hypersensitivity, Delayed; Immunity; Lymphocyte Activation; Lymphocytes; Lymphoid Tissue; Methionine; Vitamin B 12; Vitamin B 12 Deficiency | 1981 |
The deoxyuridine suppression test: a review of its clinical and research applications.
Topics: Alcoholism; Anemia, Hemolytic; Anticonvulsants; Bone Marrow Cells; Bone Marrow Diseases; Cells; Deoxyuridine; Erythrocytes, Abnormal; Female; Fluorouracil; Folic Acid; Folic Acid Deficiency; Formyltetrahydrofolates; Homocysteine; Humans; Hypothyroidism; Lymphocyte Activation; Methionine; Pregnancy; Pregnancy Complications; Statistics as Topic; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1981 |
Hyperhomocysteinaemia: a role in the accelerated atherogenesis of chronic renal failure?
Topics: Adult; Age Factors; Arteriosclerosis; Cystathionine beta-Synthase; Cysteine; Female; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Humans; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Sex Factors | 1995 |
Hyperhomocysteinaemia: a newly recognized risk factor for vascular disease.
Topics: Arteriosclerosis; Betaine; Coronary Disease; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Methionine; Pyridoxine; Risk Factors; Vascular Diseases | 1994 |
Sulfur amino acid metabolism and its regulation in fungi: studies with Aspergillus nidulans.
Topics: Amino Acids, Sulfur; Aspergillus nidulans; Cysteine; Folic Acid; Methionine; Mutation | 1993 |
The role of folate, choline, and methionine in carcinogenesis induced by methyl-deficient diets.
Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Humans; Liver Neoplasms; Methionine; Neoplasms | 1996 |
Homocysteinemia and vascular disease in end-stage renal disease.
Topics: Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Male; Methionine; Middle Aged; Pyridoxine; Thrombosis; Vitamin B 12 | 1996 |
Disturbances of one-carbon metabolism in neuropsychiatric disorders: a review.
Topics: Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Neurocognitive Disorders; S-Adenosylmethionine; Schizophrenia | 1997 |
Folic acid in the prevention of birth defects.
Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Methionine; Neural Tube Defects; Preconception Care; Pregnancy; Prenatal Care | 1996 |
[Folates and the neural tube. Review of the literature].
Topics: Animals; Europe; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Methionine; Methylation; Neural Crest; Neural Tube Defects; Preconception Care; Pregnancy; Prenatal Care; Prevalence; Risk Factors | 1997 |
Remethylation defects: guidelines for clinical diagnosis and treatment.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Betaine; Child, Preschool; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Oxidoreductases Acting on CH-NH Group Donors; Practice Guidelines as Topic; Vitamin B 12 | 1998 |
Relevance of vitamins, homocysteine and other metabolites in neuropsychiatric disorders.
Topics: Central Nervous System Diseases; Citrates; Demyelinating Diseases; Folic Acid; Homocysteine; Humans; Mental Disorders; Methionine; Methylmalonic Acid; Vitamin B 12 | 1998 |
Neural tube defects, vitamins and homocysteine.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Rats; Spinal Dysraphism | 1998 |
[Methylenetetrahydrofolate reductase deficiency].
Topics: Biomarkers; Child, Preschool; Cystathionine; Folic Acid; Genes, Recessive; Humans; Infant; Infant, Newborn; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Vitamin B 12 | 1998 |
Hyperhomocysteinemia, atherosclerosis and thrombosis.
Topics: Adult; Aged; Animals; Arteriosclerosis; Avitaminosis; Case-Control Studies; Clinical Trials as Topic; Cohort Studies; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle, Smooth, Vascular; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Primates; Prospective Studies; Pyridoxine; Risk Factors; Smoking; Tamoxifen; Thrombophilia; Thrombosis; Vitamin B 12 | 1999 |
MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis.
Topics: Adenoma; Carcinoma; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors | 1999 |
[Hyperhomocysteinemia, a risk factor for atherosclerosis: causes and effects].
Topics: Age Factors; Arterial Occlusive Diseases; Arteriosclerosis; Cerebrovascular Disorders; Coronary Disease; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Metabolism; Lipoproteins; Male; Meta-Analysis as Topic; Methionine; Middle Aged; Peripheral Vascular Diseases; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors | 1999 |
Homocysteine and endothelial dysfunction: a link with cardiovascular disease.
Topics: Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Methionine; Reactive Oxygen Species | 2000 |
Homocysteine and ischaemic heart disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Cohort Studies; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Ischemia; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Retrospective Studies | 1999 |
Preventive health care, 2000 update: screening and management of hyperhomocysteinemia for the prevention of coronary artery disease events. The Canadian Task Force on Preventive Health Care.
Topics: Aged; Arteriosclerosis; Canada; Coronary Disease; Dietary Supplements; Disease Susceptibility; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Methionine; Preventive Medicine; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12 | 2000 |
Homocysteine and renal disease.
Topics: Adult; Arteriosclerosis; Cardiovascular Diseases; Case-Control Studies; Child; Endothelium, Vascular; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Life Tables; Male; Methionine; Peritoneal Dialysis; Prospective Studies; Pyridoxine; Renal Dialysis; Survival Analysis; Thrombophilia; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Vascular complications of severe hyperhomocysteinemia in patients with homocystinuria due to cystathionine beta-synthase deficiency: effects of homocysteine-lowering therapy.
Topics: Adolescent; Adult; Aged; Australia; Child; Child, Preschool; Cohort Studies; Cystine; Drug Resistance; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Ireland; Male; Methionine; Middle Aged; Netherlands; Pyridoxine; Risk; Risk Factors; Thrombophilia; Vascular Diseases; Vitamin B 12 | 2000 |
Clotting disorders and placental abruption: homocysteine--a new risk factor.
Topics: Abruptio Placentae; Blood Coagulation Disorders; Endothelium, Vascular; Female; Fetal Growth Retardation; Folic Acid; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Pregnancy Complications, Hematologic; Risk Factors | 2001 |
[From gene to disease; from homocysteine to hyperhomocysteinemia].
Topics: Cystathionine beta-Synthase; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Hyperhomocysteinemia; Methionine; Mutation; Risk Factors; Vascular Diseases | 2001 |
Nutritional regulation of homocysteine: effects of drugs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Drug Interactions; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Methionine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6 | 2001 |
Epidemiologic studies of folate and colorectal neoplasia: a review.
Topics: Colorectal Neoplasms; Diet; Female; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Humans; Male; Methionine; Risk Factors | 2002 |
In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.
Topics: Deuterium Oxide; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Kidney Failure, Chronic; Methionine; Methylation; Serine; Tomography, Emission-Computed; Tritium | 2002 |
Pharmacotherapy of hyperhomocysteinaemia in patients with thrombophilia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Pyridoxine; Renal Insufficiency; Thrombophilia; Vitamin B 12; Vitamins | 2002 |
Genetic basis of neural tube defects. II. Genes correlated with folate and methionine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carrier Proteins; Cystathionine beta-Synthase; Ferredoxin-NADP Reductase; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Multifactorial Inheritance; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Receptors, Cell Surface | 2002 |
Do disturbances within the folate pathway contribute to low birth weight in malaria?
Topics: Female; Fetal Growth Retardation; Folic Acid; Humans; Incidence; Infant, Low Birth Weight; Infant, Newborn; Malaria, Falciparum; Methionine; Models, Biological; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome | 2003 |
The methionine-homocysteine cycle and its effects on cognitive diseases.
Topics: Alzheimer Disease; Cardiovascular Diseases; Cognition Disorders; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Memory Disorders; Methionine; Methionine Adenosyltransferase; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2003 |
ENZYMATIC ASPECTS OF FOLIC ACID.
Topics: Amidohydrolases; Aminopterin; Chromatography; Clostridium; Escherichia coli; Floxuridine; Folic Acid; Ligases; Liver; Lyases; Methionine; Methotrexate; Micrococcus; Oxidoreductases; Pseudomonas; Research; Spectrophotometry; Transferases; Tritium; Vitamin B 12 | 1963 |
[THE SIGNIFICANCE OF FOLIC ACID AND VITAMIN B 12 FOR CELLULAR METABOLISM].
Topics: Adenosine Triphosphate; Celiac Disease; DNA; Folic Acid; Hematinics; Humans; Intestinal Diseases; Metabolism; Methionine; Vitamin B 12 | 1964 |
[BIOSYNTHESIS OF METHYL GROUP OF METHIONINE].
Topics: Alkylation; Amino Acids; Cysteine; Folic Acid; Homocysteine; Metabolism; Methionine; Research; Vitamin B 12 | 1964 |
DNA methylation, cancer susceptibility, and nutrient interactions.
Topics: Animals; Choline Deficiency; Deficiency Diseases; Diet; Disease Susceptibility; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Neoplasms; Selenium | 2004 |
Homocysteine and cardiovascular disease: interactions between nutrition, genetics and lifestyle.
Topics: Avitaminosis; Cardiovascular Diseases; Creatinine; Folic Acid; Homocysteine; Humans; Incidence; Kidney Diseases; Life Style; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Physiological Phenomena; Polymorphism, Genetic; Pyridoxal; Riboflavin; Vitamin B 12 | 2004 |
The impact of metabolism on DNA methylation.
Topics: Alzheimer Disease; Animals; Arteriosclerosis; DNA Methylation; Folic Acid; Gene Expression Regulation; Glycine N-Methyltransferase; Homocysteine; Humans; Methionine; Methyltransferases; Models, Biological; S-Adenosylmethionine | 2005 |
The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence.
Topics: Carotenoids; Cell Transformation, Neoplastic; Cysteine; Diet; Female; Folic Acid; Homocysteine; Humans; Methionine; Nutritional Physiological Phenomena; Uterine Cervical Neoplasms; Vitamins | 2005 |
The significance of folic acid for epilepsy patients.
Topics: Anticonvulsants; Epilepsy; Female; Folic Acid; History, 20th Century; Homocysteine; Humans; Male; Methionine; Models, Biological; Neural Tube Defects; Pregnancy; Vascular Diseases | 2005 |
Abnormal folate metabolism in mothers with Down syndrome offspring: review of the literature.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; DNA; Down Syndrome; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Homocystinuria; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mothers; Mutation | 2006 |
Disruption of methyl group metabolism by ethanol.
Topics: Animals; Central Nervous System Depressants; Ethanol; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Liver; Methionine; Rats; Swine; Swine, Miniature | 2005 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Perinatal choline influences brain structure and function.
Topics: Brain; Choline; Female; Fetal Development; Folic Acid; Humans; Infant, Newborn; Lactation; Male; Methionine; Nootropic Agents; Perinatal Care; Pregnancy | 2006 |
Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet.
Topics: Amino Acids, Sulfur; Animals; Choline; Diet; DNA Methylation; Drug Interactions; Endocrine System; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Methylation; Nutritional Requirements; Pregnancy; Proteins; S-Adenosylmethionine | 2006 |
Neural tube defects and folate: case far from closed.
Topics: Animals; Central Nervous System; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects | 2006 |
The fetal origins of memory: the role of dietary choline in optimal brain development.
Topics: Brain; Choline; Diet; Female; Folic Acid; Humans; Infant; Methionine; Nootropic Agents; Pregnancy; Sex Factors | 2006 |
[Risk factors for cardiovascular diseases: what is the role for homocysteine?].
Topics: Cardiovascular Diseases; Folic Acid; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline.
Topics: Animals; Brain; Choline; Choline Deficiency; Diet; Epigenesis, Genetic; Estrogens; Folic Acid; Humans; Methionine; Nutritional Requirements; Polymorphism, Genetic; Response Elements; Vitamin B Complex | 2007 |
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
Topics: Animals; Betaine; Disease Models, Animal; Folic Acid; Humans; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine | 2007 |
[Measurement of methylmalonic acid, homocysteine and methionine in cobalamin and folate deficiencies and homocysteinuria].
Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Diagnosis, Differential; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Infant; Infant, Newborn; Methionine; Methylmalonic Acid; Vitamin B 12 Deficiency | 2008 |
Methylenetetrahydrofolate reductase (MTHFR): a novel target for cancer therapy.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Delivery Systems; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oligonucleotides, Antisense | 2008 |
Mecobalamin.
Topics: Aged; Alprostadil; Animals; Cobamides; Coenzymes; Diabetic Neuropathies; Drug Administration Routes; Drug Therapy, Combination; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Kidney Failure, Chronic; Male; Metformin; Methionine; Methyltransferases; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Renal Dialysis; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2008 |
Folate and methionine metabolism in autism: a systematic review.
Topics: Autistic Disorder; Folic Acid; Humans; Methionine | 2010 |
Genetic variations in multiple myeloma I: effect on risk of multiple myeloma.
Topics: DNA Repair; Female; Folic Acid; Gene-Environment Interaction; Genetic Variation; Humans; Inflammation; Male; Methionine; Multiple Myeloma; Plasma Cells; Risk Factors; Xenobiotics | 2012 |
Folate metabolic pathways in Leishmania.
Topics: Amino Acid Oxidoreductases; Animals; Carrier Proteins; Folic Acid; Host-Parasite Interactions; Iron-Sulfur Proteins; Leishmania; Metabolic Networks and Pathways; Methionine; Multienzyme Complexes; Pteridines; Purines; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidylate Synthase; Transferases | 2011 |
The impact of nutrition on differential methylated regions of the genome.
Topics: Adult; Amino Acids; Animals; Choline; DNA Methylation; Female; Folic Acid; Food; Genistein; Genome, Human; Humans; Leptin; Methionine; Pregnancy; Proteins | 2011 |
A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension.
Topics: Animals; Carbon-Sulfur Lyases; Diet; Folic Acid; Humans; Life Expectancy; Methionine; Neoplasms; Phenotype; Purine-Nucleoside Phosphorylase | 2012 |
Methionine, homocysteine, one carbon metabolism and fetal growth.
Topics: Adult; Animals; Carbon; Dietary Proteins; Energy Intake; Female; Fetal Development; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Rats; Vitamin B 12; Vitamins | 2012 |
Roles of one-carbon metabolism in preimplantation period--effects on short-term development and long-term programming--.
Topics: Animals; Blastocyst; Cattle; Embryonic Development; Epigenesis, Genetic; Female; Folic Acid; Humans; Male; Methionine; Mice; Oocytes; Rats | 2012 |
Folate, colorectal cancer and the involvement of DNA methylation.
Topics: Animals; Colon; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; Folic Acid; Humans; Methionine; Vitamin B Complex | 2012 |
B-Vitamin dependent methionine metabolism and alcoholic liver disease.
Topics: Epigenesis, Genetic; Ethanol; Folic Acid; Gene Expression Regulation; Humans; Kidney; Liver; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine; Vitamin B Complex; Vitamin B Deficiency | 2013 |
Folate, alcohol, and liver disease.
Topics: Absorption; Alcohol Drinking; Animals; Antioxidants; Disease Models, Animal; Epigenesis, Genetic; Ethanol; Folic Acid; Folic Acid Deficiency; Gene Expression; Humans; Intestine, Small; Liver; Liver Diseases, Alcoholic; Methionine; Methylation | 2013 |
The nutritional burden of methylation reactions.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Creatine; Diet; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nutritional Status; Phosphatidylcholines | 2013 |
Methyl nutrients, DNA methylation, and cardiovascular disease.
Topics: Amino Acids; Atherosclerosis; Cardiovascular Diseases; Cysteine; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Status; Risk Factors; S-Adenosylmethionine; Vitamin B Complex | 2014 |
Methoxistasis: integrating the roles of homocysteine and folic acid in cardiovascular pathobiology.
Topics: Cardiovascular Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Oxidation-Reduction; Randomized Controlled Trials as Topic; Vitamin B Complex; Vitamin B Deficiency; Vitamins | 2013 |
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine | 2013 |
Nutriepigenetic regulation by folate-homocysteine-methionine axis: a review.
Topics: Animals; Epigenesis, Genetic; Fatigue Syndrome, Chronic; Folic Acid; Folic Acid Deficiency; Gene-Environment Interaction; Homocysteine; Humans; Methionine; Neural Tube Defects; Progeria | 2014 |
Folate-related nutrients, genetic polymorphisms, and colorectal cancer risk: the fukuoka colorectal cancer study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Alleles; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Food; Genotype; Humans; Japan; Male; Methionine; Middle Aged; Polymorphism, Genetic; Risk; Thymidylate Synthase; Vitamins; Young Adult | 2013 |
Lifetime requirement of the methionine cycle for neuronal development and maintenance.
Topics: Developmental Disabilities; Female; Folic Acid; Homocysteine; Humans; Methionine; Pregnancy; Prenatal Care; S-Adenosylmethionine; Vitamin B 12; Vitamin B Complex | 2014 |
Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke.
Topics: Aldehyde Dehydrogenase; Carbon; Folic Acid; Genome-Wide Association Study; Genotype; Homocysteine; Humans; Methionine; Oxidoreductases Acting on CH-NH Group Donors; Stroke; Vitamin B 12 | 2014 |
Homocysteine and DNA methylation: a review of animal and human literature.
Topics: Animals; Case-Control Studies; Diet; Dietary Supplements; DNA Methylation; Female; Folic Acid; Gene Knockout Techniques; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Models, Animal; Vitamin B Complex; Vitamin B Deficiency | 2014 |
Homocysteine, iron and cardiovascular disease: a hypothesis.
Topics: Biomarkers; Cardiovascular Diseases; Cystathionine; Dietary Supplements; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Lipoproteins, LDL; Methionine; Risk Factors; S-Adenosylhomocysteine; Vitamin B Complex | 2015 |
One-carbon metabolism and epigenetic regulation of embryo development.
Topics: Animals; Embryonic Development; Energy Metabolism; Epigenesis, Genetic; Female; Folic Acid; Humans; Male; Methionine; Oocytes; Spermatogenesis | 2015 |
Methylation reactions, the redox balance and atherothrombosis: the search for a link with hydrogen sulfide.
Topics: Animals; Aspirin; Atherosclerosis; Folic Acid; Gasotransmitters; Homocysteine; Humans; Hydrogen Sulfide; Methionine; Methylation; Oxidation-Reduction; Thrombosis | 2015 |
Potential role of folate in pre-eclampsia.
Topics: Dietary Supplements; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Methionine; Oxidative Stress; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Vitamins | 2015 |
One-carbon metabolism and epigenetics: understanding the specificity.
Topics: Animals; Chromatin; Epigenesis, Genetic; Epigenomics; Folic Acid; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Metabolic Networks and Pathways; Methionine; Methylation; S-Adenosylmethionine; Substrate Specificity | 2016 |
The dynamics of methionine supply and demand during early development.
Topics: Betaine; Child Development; Choline; Creatine; Diet; Dietary Supplements; DNA Methylation; Folic Acid; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Methionine; Phosphatidylcholines | 2016 |
The Pediatric Methionine Requirement Should Incorporate Remethylation Potential and Transmethylation Demands.
Topics: Amino Acids; Betaine; Diet; DNA Methylation; Folic Acid; Humans; Methionine; Methylation; Neonatology; Nutritional Requirements; Phosphatidylcholines; Protein Biosynthesis | 2016 |
The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review).
Topics: Aminohydrolases; Antineoplastic Agents; Fluorouracil; Folic Acid; Folic Acid Antagonists; Gastrointestinal Neoplasms; Glycine Hydroxymethyltransferase; Humans; Metabolic Networks and Pathways; Metabolome; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); MicroRNAs; Mitochondria; Molecular Targeted Therapy; Multienzyme Complexes; Nucleosides; Nucleotides; Oxidoreductases Acting on CH-NH Group Donors; Purines; Reactive Oxygen Species; Serine | 2017 |
[Research advances in the association between maternal intake of methyl donor nutrients during pregnancy and DNA methylation in offspring].
Topics: Betaine; Choline; DNA Methylation; Female; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Vitamin B 12 | 2017 |
The Interactions Between Kynurenine, Folate, Methionine and Pteridine Pathways in Obesity.
Topics: Animals; Folic Acid; Humans; Inflammation; Kynurenine; Methionine; Obesity; Pteridines; Signal Transduction | 2017 |
A crucial role for maternal dietary methyl donor intake in epigenetic programming and fetal growth outcomes.
Topics: Animals; Birth Weight; Carbon; Choline; Diet; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Fetal Development; Fetus; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Nutrients; Placenta; Pregnancy; Vitamin B Complex; Zinc | 2018 |
One-Carbon Metabolism: Linking Nutritional Biochemistry to Epigenetic Programming of Long-Term Development.
Topics: Animals; Diet; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Folic Acid; Genetic Variation; Humans; Male; Metabolic Networks and Pathways; Methionine | 2019 |
Medicines associated with folate-homocysteine-methionine pathway disruption.
Topics: Enzyme Inhibitors; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Pregnancy; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Vitamin B 12 Deficiency | 2019 |
Toward a better understanding of folate metabolism in health and disease.
Topics: Animals; Cell Proliferation; Epigenesis, Genetic; Folic Acid; Humans; Methionine; Mitochondria; Oxygen Consumption; Protein Biosynthesis; Thymidine Monophosphate | 2019 |
Methionine metabolism in health and cancer: a nexus of diet and precision medicine.
Topics: Animals; Carbon; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Deletion; Histones; Humans; Methionine; Neoplasms; Nutritional Sciences; Oxidation-Reduction; Polyamines; Precision Medicine; RNA | 2019 |
One-Carbon Metabolism and Nonalcoholic Fatty Liver Disease: The Crosstalk between Nutrients, Microbiota, and Genetics.
Topics: Animals; Betaine; Carbon; Choline; Disease Progression; Female; Folic Acid; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lipid Metabolism; Liver; Methionine; Microbiota; Models, Genetic; Non-alcoholic Fatty Liver Disease; Nutrients; Polymorphism, Single Nucleotide; Pregnancy; Prenatal Exposure Delayed Effects; Risk | 2020 |
Symposium review: One-carbon metabolism and methyl donor nutrition in the dairy cow.
Topics: Animal Nutritional Physiological Phenomena; Animals; Cattle; Diet; Female; Folic Acid; Methionine; Tetrahydrofolates | 2020 |
Genetic, epigenetic and genomic mechanisms of methionine dependency of cancer and tumor-initiating cells: What could we learn from folate and methionine cycles.
Topics: Cell Line, Tumor; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Methionine; Neoplasms; Neoplastic Stem Cells; Vitamin B 12 | 2020 |
Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery.
Topics: Betaine; Cardiovascular Diseases; Choline; Dietary Supplements; DNA Methylation; Eating; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methionine; Nutritional Physiological Phenomena; Renal Insufficiency, Chronic; Uremia; Vitamin B 12; Vitamin B 6 | 2020 |
Gut microbiota and the periodontal disease: role of hyperhomocysteinemia.
Topics: Dysbiosis; Folic Acid; Gastrointestinal Microbiome; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Periodontitis; Probiotics | 2021 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
Vitamin B6, vitamin B12 and methionine and risk of pancreatic cancer: a meta-analysis.
Topics: Diet; Folic Acid; Humans; Methionine; Pancreatic Neoplasms; Risk Factors; Vitamin B 12; Vitamin B 6 | 2020 |
One Carbon Metabolism and Mammalian Pregnancy Outcomes.
Topics: Animals; Carbon; Embryo, Mammalian; Epigenesis, Genetic; Female; Folic Acid; Humans; Mammals; Methionine; Pregnancy; Pregnancy Outcome; Pregnancy, Animal | 2021 |
Shared Biological Pathways between Antipsychotics and Omega-3 Fatty Acids: A Key Feature for Schizophrenia Preventive Treatment?
Topics: Animals; Antipsychotic Agents; Fatty Acids, Omega-3; Folic Acid; Humans; Methionine; Myelin Sheath; Schizophrenia; Synaptic Transmission | 2021 |
Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks.
Topics: Carbon Cycle; Cardiovascular Diseases; Diabetes Mellitus; Epigenesis, Genetic; Female; Folic Acid; Heart Disease Risk Factors; Homocysteine; Humans; Inflammation; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vascular Diseases; Vitamin B 12 | 2021 |
Interactions between Radiation and One-Carbon Metabolism.
Topics: Carbon; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Methionine; Neoplasms | 2022 |
COVID-19 and One-Carbon Metabolism.
Topics: Carbon; COVID-19; Folic Acid; Homocysteine; Humans; Methionine; Post-Acute COVID-19 Syndrome; SARS-CoV-2; Vitamin B 12 | 2022 |
Betaine consumption as a new clinical approach to treatment and prophylaxis of folate-related pathologies.
Topics: Amino Acids; Betaine; Betaine-Homocysteine S-Methyltransferase; Folic Acid; Homocysteine; Humans; Methionine | 2023 |
Methyl Donors, Epigenetic Alterations, and Brain Health: Understanding the Connection.
Topics: Animals; Brain; Carbon; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Methionine; Micronutrients; S-Adenosylmethionine | 2023 |
Folate-Methionine Cycle Disruptions in ASD Patients and Possible Interventions: A Systematic Review.
Topics: Autism Spectrum Disorder; Child; Dietary Supplements; Folic Acid; Humans; Methionine; Racemethionine; Vitamin B 12 | 2023 |
Arginine, Transsulfuration, and Folic Acid Pathway Metabolomics in Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.
Topics: Arginine; Cysteine; Folic Acid; Homocysteine; Humans; Metabolomics; Methionine; Nitric Oxide; Racemethionine; Vitamins | 2023 |
Folate and retinal vascular diseases.
Topics: Diabetic Retinopathy; Endothelial Cells; Folic Acid; Glucose; Homocysteine; Humans; Hyperhomocysteinemia; Methionine | 2023 |
33 trial(s) available for methionine and folic acid
| Article | Year |
|---|---|
Oral methionine loading as a cause of acute serum folate deficiency: its relevance to parenteral nutrition.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Methionine; Parenteral Nutrition | 1978 |
Hyperhomocysteinaemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Arterial Occlusive Diseases; Biomarkers; Blood Pressure; Cholesterol; Endothelium, Vascular; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Middle Aged; Pyridoxine; Smoking; Thrombomodulin; Time Factors; Tissue Plasminogen Activator; von Willebrand Factor | 1995 |
In vivo methylation capacity is not impaired in healthy men during short-term dietary folate and methyl group restriction.
Topics: Administration, Oral; Adult; Carnitine; Choline; Choline Deficiency; Creatinine; Cross-Over Studies; Diet; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Male; Methionine; Methylation; Middle Aged; Niacinamide; Time Factors | 1995 |
Treatment of hyperhomocysteinemia in renal transplant recipients. A randomized, placebo-controlled trial.
Topics: Drug Therapy, Combination; Factor Analysis, Statistical; Folic Acid; Homocysteine; Humans; Kidney Transplantation; Methionine; Pyridoxine; Risk Factors; Vitamin B 12 | 1997 |
Effects of folic acid and vitamin B6 supplementation on women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction.
Topics: Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Medical History Taking; Methionine; Pre-Eclampsia; Pregnancy; Pyridoxine; Statistics, Nonparametric | 1998 |
Correlation between total homocysteine and cyclosporine concentrations in cardiac transplant recipients.
Topics: Adult; Aged; Cyclosporine; Female; Folic Acid; Heart Transplantation; Homocysteine; Humans; Immunosuppressive Agents; Kidney Glomerulus; Linear Models; Male; Metabolic Diseases; Methionine; Middle Aged; Postoperative Complications; Vitamin B 12 | 1998 |
Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.
Topics: Adult; Betaine; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome | 1999 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Effects of high-dose folic acid and pyridoxine on plasma and erythrocyte sulfur amino acids in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Sulfur; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Pyridoxine; Reference Values; Renal Dialysis; Statistics, Nonparametric; Uremia | 1999 |
Variability of fasting and post-methionine plasma homocysteine levels in normo- and hyperhomocysteinaemic individuals.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Analysis of Variance; Fasting; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases; Statistics, Nonparametric | 1999 |
Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial.
Topics: Blood Pressure; Coronary Artery Disease; Family; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Risk Factors | 2000 |
Low-dose folic acid supplementation does not influence plasma methionine concentrations in young non-pregnant women.
Topics: Adolescent; Adult; Contraceptives, Oral; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Vitamin B 12 | 1999 |
Pyridoxine improves endothelial function in cardiac transplant recipients.
Topics: Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Follow-Up Studies; Heart Transplantation; Homocysteine; Humans; Male; Methionine; Middle Aged; Pyridoxine | 2001 |
Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy.
Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Biomarkers; Cystathionine; Cysteine; Fasting; Female; Folic Acid; HIV Infections; HIV-1; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Multivariate Analysis; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Sarcosine; Vitamin B 6 | 2001 |
Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure.
Topics: Aged; Betaine; Cross-Over Studies; Drug Therapy, Combination; Fasting; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Methionine; Middle Aged; Pyridoxine; Sarcosine | 2002 |
Efficacy of methylcobalamin on lowering total homocysteine plasma concentrations in haemodialysis patients receiving high-dose folic acid supplementation.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Osmolar Concentration; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2002 |
Post-methionine-load hyperhomocysteinemia and increased lipoprotein(a) are associated with renal metabolic dysfunction: a hypothesis.
Topics: Apolipoproteins A; Creatinine; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Diseases; Lipoprotein(a); Male; Methionine; Middle Aged; Vitamin B 12 | 2002 |
The effect of B-vitamins on hyperhomocysteinemia in patients on antiepileptic drugs.
Topics: Adult; Anticonvulsants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Methionine; Middle Aged; Pyridoxic Acid; Riboflavin; Selectins; Vascular Cell Adhesion Molecule-1; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2002 |
Effect of protein and methionine intakes on plasma homocysteine concentrations: a 6-mo randomized controlled trial in overweight subjects.
Topics: Adolescent; Adult; Analysis of Variance; Body Weight; Diet; Diet, Protein-Restricted; Dietary Proteins; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Obesity; Vitamin B 12 | 2002 |
Effects of acute hyperhomocysteinemia on the neurovascular coupling mechanism in healthy young adults.
Topics: Acute Disease; Adult; Blood Flow Velocity; Brain; Cerebrovascular Circulation; Cross-Over Studies; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Photic Stimulation; Posterior Cerebral Artery; Reference Values; Systole; Ultrasonography, Doppler, Transcranial | 2003 |
Plasma total homocysteine in Mexican rural and urban women fed typical model diets.
Topics: Adolescent; Adult; Cross-Over Studies; Diet; Fasting; Female; Folic Acid; Homocysteine; Humans; Methionine; Mexico; Middle Aged; Nutritional Status; Reference Values; Rural Health; Urban Health; Vitamin B 12 | 2003 |
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2004 |
Endothelial function in post-menopausal women: effect of folic acid supplementation.
Topics: Brachial Artery; Cholesterol, HDL; Cholesterol, LDL; Endothelium, Vascular; Female; Folic Acid; Humans; Methionine; Middle Aged; Nitroglycerin; Postmenopause; Vasodilation | 2004 |
Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2004 |
Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Cardiovascular Diseases; Cystathionine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Norway; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2004 |
Hormone replacement influences homocysteine levels in the methionine-loading test: a randomized placebo controlled trial in postmenopausal women.
Topics: Analysis of Variance; Blood Chemical Analysis; Double-Blind Method; Dydrogesterone; Estradiol; Estrogen Replacement Therapy; Female; Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Postmenopause; Pyridoxine; Treatment Outcome; Vitamin B 12 | 2004 |
Effect of L-methionine supplementation on plasma homocysteine and other free amino acids: a placebo-controlled double-blind cross-over study.
Topics: Adult; Aged; Amino Acids; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Urinary Tract Infections; Vitamin B 12; Vitamin B 6 | 2005 |
Betaine concentration as a determinant of fasting total homocysteine concentrations and the effect of folic acid supplementation on betaine concentrations.
Topics: Administration, Oral; Aged; Betaine; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged | 2005 |
Effects of low- or high-dose hormone therapy on fasting and post-methionine homocysteine levels in postmenopausal women.
Topics: Dose-Response Relationship, Drug; Estradiol; Estrogen Replacement Therapy; Fasting; Female; Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Norethindrone; Postmenopause; Prospective Studies; Risk Factors; Treatment Outcome; Vitamin B 12 | 2006 |
Folate, vitamin B6, vitamin B12, and methionine intakes and risk of stroke subtypes in male smokers.
Topics: Aged; Feeding Behavior; Finland; Folic Acid; Health Status; Humans; Male; Methionine; Middle Aged; Multivariate Analysis; Nutrition Surveys; Nutritional Status; Prospective Studies; Risk; Risk Assessment; Risk Factors; Smoking; Stroke; Vitamin B 12; Vitamin B 6 | 2008 |
Supplementation with a multivitamin containing 800 microg of folic acid shortens the time to reach the preventive red blood cell folate concentration in healthy women.
Topics: Adolescent; Adult; Diet; Diet Records; Dietary Supplements; Double-Blind Method; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Methionine; Micronutrients; Neural Tube Defects; Nutritional Status; Reference Values; Riboflavin; Time Factors; Vitamin B 12; Vitamin B 6; Young Adult | 2009 |
Short-term creatine supplementation does not reduce increased homocysteine concentration induced by acute exercise in humans.
Topics: Adolescent; Creatine; Cysteine; Dietary Supplements; Double-Blind Method; Energy Intake; Exercise; Feeding Behavior; Folic Acid; Glycine; Healthy Volunteers; Homocysteine; Humans; Male; Methionine; S-Adenosylmethionine; Soccer; Vitamin B 12 | 2014 |
Concentrations of vitamin B12 and folate in maternal serum and fetal fluids, metabolite interrelationships, and hepatic transcript abundance of key folate and methionine cycle genes: the impacts of maternal nutrition during the first 50 d of gestation.
Topics: Animals; Carbon; Cattle; Diet; Female; Folic Acid; Glycine; Liver; Methionine; Pregnancy; Racemethionine; Serine; Vitamin B 12 | 2023 |
748 other study(ies) available for methionine and folic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Vitamin B12--folate interrelations.
Topics: Anemia, Megaloblastic; DNA; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Glycine; Homocysteine; Humans; Methionine; Methylmalonyl-CoA Mutase; Nervous System Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1976 |
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Vitamin B 12 | 1975 |
Schizophrenia, epilepsy, cancer, methionine, and folate metabolism. Pathogenesis of schizophrenia.
Topics: Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Antagonists; Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; Schizophrenia | 1975 |
Reduction of N-nitrosodiethylamine carcinogenesis in rats by lipotrope or amino acid supplementation of a marginally deficient diet.
Topics: Amino Acids; Animals; Body Weight; Carcinoma, Hepatocellular; Choline; Diet; Dietary Fats; Diethylnitrosamine; Esophageal Neoplasms; Folic Acid; Hemangioendothelioma; Lipotropic Agents; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Nicotinic Acids; Nitrosamines; Rats | 1977 |
High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carcinoma 256, Walker; Cell Line; Cell Transformation, Neoplastic; Folic Acid; Homocysteine; Methionine; Simian virus 40 | 1976 |
5-methyltetrahydrofolate: synthesis and utilization in normal and SV40-transformed BHK-21 cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; Folic Acid; Homocysteine; Kidney; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Simian virus 40; Tetrahydrofolates; Vitamin B 12 | 1977 |
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides | 1977 |
Effect of dietary thyroid powder on urinary excretion of formiminoglutamic acid and methylmalonic acid.
Topics: Animals; Dietary Proteins; Folic Acid; Formiminoglutamic Acid; Glutarates; Histidine; Male; Malonates; Methionine; Methylmalonic Acid; Rats; Thyroid (USP); Thyroid Hormones; Vitamin B 12; Vitamin B 12 Deficiency | 1979 |
Studies on methanol toxicity and formate metabolism in isolated hepatocytes. The role of methionine in folate-dependent reactions.
Topics: Animals; Catalase; Folic Acid; Folic Acid Deficiency; Formates; Glycolates; Histidine; In Vitro Techniques; Kinetics; Liver; Male; Methanol; Methionine; Peroxides; Rats | 1979 |
Methionine toxicity in chicks and poults.
Topics: Animals; Betaine; Bone Diseases, Developmental; Chickens; Folic Acid; Glycine; Homocystine; Male; Methionine; Paralysis; Poultry Diseases; Turkeys | 1978 |
Methionine and the "methyl folate trap".
Topics: Folic Acid; Humans; Liver; Methionine; Vitamin B 12 Deficiency | 1978 |
Rapid separation of low molecular weight solutes from liposomes without dilution.
Topics: Chromatography, Gel; Folic Acid; Inulin; Leucine; Liposomes; Methionine; Methotrexate; Sucrose; Thymidine | 1978 |
Biosynthesis of ribosylthymine in the transfer RNA of Streptococcus faecalis: a folate-dependent methylation not involving S-adenosylmethionine.
Topics: Enterococcus faecalis; Folic Acid; Formates; Methionine; Methylation; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Thymine | 1975 |
The metabolic consequences of vitamin B-12/methionine deficiency in rats.
Topics: Animals; Bacteriological Techniques; Chromatography, Ion Exchange; Deficiency Diseases; Folic Acid; Lacticaseibacillus casei; Liver; Methionine; Rats; Vitamin B 12 Deficiency | 1975 |
The folate-mediated synthesis of ribothymidylate in transfer ribonucleic acid, and evidence for multifunctional enzymes in one-carbon metabolism in eukaryotic sources.
Topics: Aminohydrolases; Animals; Bacillus cereus; Bacillus subtilis; Enterococcus faecalis; Folic Acid; Formate-Tetrahydrofolate Ligase; Liver; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Molecular Weight; RNA, Transfer; Saccharomyces cerevisiae; Sheep; Thymine Nucleotides | 1976 |
Effect of methionine on the metabolism of formate and histidine by rats fed folate/vitamin B-12-methionine-deficient diet.
Topics: Animals; Carbon Dioxide; Catalase; Folic Acid; Folic Acid Deficiency; Formates; Formiminoglutamic Acid; Histidine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1977 |
Uptake and metabolism of [3H]folate by normal and by vitamin B-12- and methionine-deficient rats.
Topics: Animals; Folic Acid; Kidney; Liver; Male; Methionine; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1977 |
A methionine-reversible folate deficiency in rats following the acute administration of diethylnitrosamine and alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Animals; Choline; Diet; Diethylnitrosamine; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Liver; Male; Methionine; Nitrosamines; Rats; S-Adenosylmethionine; Thiocyanates; Time Factors | 1977 |
[Folic acid metabolism in Lesch-Nythan syndrome].
Topics: Folic Acid; Glycine; Histidine; Humans; Lesch-Nyhan Syndrome; Methionine; Serine | 1977 |
Effect of methionine on hepatic folate metabolism in rats fed a vitamin B12- and methionine-deficient diet.
Topics: Animals; Biological Transport; Folic Acid; Liver; Male; Methionine; Rats; Time Factors; Vitamin B 12 Deficiency | 1977 |
Alterations in the chain length of pteroylpoly-gamma-glutamates and in the activity of pteroylpoly-gamma-glutamate hydrolase in response to changes in the steady state of one carbon metabolism.
Topics: Animals; Carboxypeptidases; Caseins; Choline Deficiency; Coturnix; Dietary Proteins; Folic Acid; gamma-Glutamyl Hydrolase; Glutamates; Liver; Male; Methionine; Quail | 1977 |
[Mechanism of anemia in selenium poisoning rats. (II). Behavior of vitamin B12 and mechanism of anemia by selenium dosing (author's transl)].
Topics: Anemia; Animals; Female; Folic Acid; In Vitro Techniques; Liver; Methionine; Rats; Selenium; Tissue Distribution; Vitamin B 12 | 1977 |
[Changes in the end part of the ECG ventricular complex under the effect of digitalis preparations and their combination with metabolic preparations].
Topics: Adenosine Triphosphate; Digitalis Glycosides; Drug Therapy, Combination; Electrocardiography; Folic Acid; Heart; Heart Valve Diseases; Humans; Methionine; Orotic Acid; Pantothenic Acid; Vitamin B 12 | 1977 |
The regulation of the degradation of methionine and of the one-carbon units derived from histidine, serine and glycine.
Topics: Animals; Carbon Dioxide; Enzyme Activation; Folic Acid; Formates; Formiminoglutamic Acid; Gluconeogenesis; Glucose; Glycine; Histidine; Homocysteine; In Vitro Techniques; Liver; Methionine; Oxidoreductases Acting on CH-NH Group Donors; Perfusion; Rats; Serine; Tetrahydrofolates | 1976 |
The regulation of folate and methionine metabolism.
Topics: Amino Acids; Animals; Carbon Dioxide; Folic Acid; Formates; Formiminoglutamic Acid; Glucose; Glutamates; Histidine; In Vitro Techniques; Liver; Methionine; Rats; Starvation; Urocanic Acid | 1976 |
Regulation of methionine synthetase in L-cells by vitamin B-12, folate and methionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Culture Media; Cycloheximide; Folic Acid; Kinetics; L Cells; Methionine; Methyltransferases; Vitamin B 12 | 1976 |
Uptake of folate and its analogue-amethopterin by mouse L-cells.
Topics: Animals; Cells, Cultured; Chloromercuribenzoates; Cycloheximide; Dactinomycin; Folic Acid; Kinetics; L Cells; Methionine; Methotrexate; Mice; Vitamin B 12 | 1976 |
Intestinal function in chronic alcoholism.
Topics: Alcohol Oxidoreductases; Alcoholism; Chronic Disease; Diet Therapy; Digestive System; Dose-Response Relationship, Drug; Ethanol; Folic Acid; Gastrointestinal Motility; Humans; Intestinal Absorption; Intestines; Malabsorption Syndromes; Methionine; Nutrition Disorders; Thiamine; Vitamin B 12; Xylose | 1975 |
Meeting report: Biochemical aspects of schizophrenia. Alabama, April 1975.
Topics: Acute Disease; Blood Platelets; Chronic Disease; Dopamine; Folic Acid; gamma-Aminobutyric Acid; Hallucinogens; Humans; Mesencephalon; Methionine; Monoamine Oxidase; Prolactin; Receptors, Dopamine; Schizophrenia; Serotonin; T-Lymphocytes | 1975 |
Isolation and properties of a thymidylate-less mutant in Saccharomyces cerevisiae.
Topics: Adenine; Folic Acid; Genes; Glycine Hydroxymethyltransferase; Histidine; Methionine; Mutation; Saccharomyces cerevisiae; Species Specificity; Thymine Nucleotides | 1975 |
Malabsorption of essential amino acids in tropical sprue.
Topics: Administration, Oral; Adult; Aged; Amino Acids, Essential; Fats; Feces; Folic Acid; Humans; Intestinal Absorption; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Serum Albumin; Sprue, Tropical; Tetracycline; Threonine; Valine; Vitamin B 12; Xylose | 1975 |
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Alcohol Oxidoreductases; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Schizophrenia; Tetrahydrofolates; Vitamin B 12 | 1975 |
Editorial: Metabolic hypotheses in schizophrenia.
Topics: Folic Acid; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Psychotic Disorders; Schizophrenia | 1975 |
Oxidation of compounds metabolized through folate coenzyme pathways in vitamin B12-deficient rats.
Topics: Amino Acids; Animals; Carbon Dioxide; Folic Acid; Formates; Glycine; Liver; Methionine; Rats; Sarcosine; Time Factors; Transferases; Vitamin B 12 Deficiency | 1975 |
5-methyl-5,6,7,8-tetrahydropteroyl oligo-gamma-L-glutamates: synthesis and kinetic studies with methionine synthetase from bovine brain.
Topics: Animals; Brain; Cattle; Folic Acid; Kinetics; Methionine; Methyltransferases; Structure-Activity Relationship; Tetrahydrofolates | 1975 |
The relationships between vitamin B12 and folic acid and the effect of methionine on folate metabolism.
Topics: Animals; Biological Transport; Diet; Folic Acid; Formiminoglutamic Acid; Histidine; Liver; Male; Methionine; Perfusion; Rats; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1975 |
Folate-dependent enzymes in cultured Chinese hamster ovary cells: induction of 5-methyltetrahydrofolate homocysteine cobalamin methyltransferase by folate and methionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Culture Media; Cycloheximide; Enzyme Induction; Folic Acid; Homocysteine; Kinetics; Methionine; Methyltransferases; Thymidylate Synthase; Time Factors; Vitamin B 12 | 1975 |
The anti-folate effect of methionine on bone marrow of normal and vitamin B12 deficient rats.
Topics: Animals; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1975 |
Methionine metabolism in BHK cells: selection and characterization of ethionine resistant clones.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Clone Cells; Drug Resistance; Ethionine; Folic Acid; Homocysteine; Methionine; Methionine Adenosyltransferase; Mutation; Norleucine; Quinone Reductases; Selenomethionine; Vitamin K | 1976 |
Effect of vitamin B12 and folate on biosynthesis of methionine from homocysteine in the nematode Caenorhabditis briggsae.
Topics: Animals; Choline; Folic Acid; Homocysteine; Methionine; Nematoda; Vitamin B 12 | 1976 |
The effects of dietary histidine, methionine and homocystine on vitamin B12 and folate levels in rat liver.
Topics: Animals; Body Weight; Female; Folic Acid; Histidine; Homocystine; Liver; Male; Methionine; Proteins; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1976 |
Plasma homocysteine in women on oral oestrogen-containing contraceptives and in men with oestrogen-treated prostatic carcinoma.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Contraceptives, Oral, Hormonal; Estradiol Congeners; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Prostatic Neoplasms; Risk Factors; Vitamin B 12 | 1992 |
Alterations in nucleotide pools in rats fed diets deficient in choline, methionine and/or folic acid.
Topics: Animals; Choline; Choline Deficiency; Chromatography, High Pressure Liquid; Diet; Folic Acid; Folic Acid Deficiency; Male; Methionine; Nucleotides; Rats; Rats, Inbred F344; Spleen | 1992 |
Methyl groups in carcinogenesis: effects on DNA methylation and gene expression.
Topics: Animals; Choline; DNA; Folic Acid; Food, Formulated; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1992 |
Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status.
Topics: Adult; Aged; Aging; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Pyridoxal Phosphate; Sex Characteristics; Vascular Diseases; Vitamin B 12 | 1992 |
Inhibition of cobalamin-dependent enzymes by cobalamin analogues in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Folic Acid; Homocysteine; Male; Methionine; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Nitrous Oxide; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Succinates; Succinic Acid; Vitamin B 12 | 1991 |
Plasma homocysteine in venous thromboembolism.
Topics: Adult; Creatinine; Cystathionine beta-Synthase; Fasting; Female; Folic Acid; Genetic Carrier Screening; Genotype; Homocysteine; Homocystinuria; Humans; Male; Methionine; Thromboembolism; Vitamin B 12 | 1991 |
Plasma homocysteine in children with acute lymphoblastic leukemia: changes during a chemotherapeutic regimen including methotrexate.
Topics: Adolescent; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Methionine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors | 1991 |
Monitoring cobalamin inactivation during nitrous oxide anesthesia by determination of homocysteine and folate in plasma and urine.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthesia, Intravenous; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Nitrous Oxide; Postoperative Period; Vitamin B 12 | 1991 |
Folate deficiency in chicks fed diets containing practical ingredients.
Topics: Animal Feed; Animals; Chickens; Choline; Folic Acid; Folic Acid Deficiency; Glycine max; Liver; Male; Methionine; Poultry Diseases; Weight Gain; Zea mays | 1991 |
Methylthioadenosine serves as a single carbon source to the folate co-enzyme pool in rat bone marrow cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bone Marrow; Carbon; Deoxyadenosines; Folic Acid; Formates; Glycine; Guanine; Male; Methionine; Methionine Adenosyltransferase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Serine; Thionucleosides | 1990 |
Interrelationship between serum concentrations of methionine, vitamin B12 and folate.
Topics: Adult; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 1990 |
Nitrous oxide provokes changes in folylpenta- and hexaglutamates.
Topics: Animals; Chromatography, DEAE-Cellulose; Dietary Proteins; Folic Acid; Histidine; Liver; Male; Methionine; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains | 1990 |
Studies on the earthy-musty odours in natural water (IV). Mechanism of earthy-musty odour production of actinomycetes.
Topics: Camphanes; Folic Acid; Methionine; Naphthols; Odorants; Streptomyces; Water Microbiology | 1990 |
Effect of a histidine-excess diet on a tetrahydrofolylpolyglutamate pattern in rat liver.
Topics: Animals; Caseins; Diet; Folic Acid; Food, Fortified; Histidine; Liver; Male; Methionine; Organ Size; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains | 1990 |
Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats.
Topics: Animals; Choline; Choline Deficiency; Deoxyuridine; Diet; DNA Damage; DNA Replication; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; NAD; Nucleotides; Rats; Rats, Inbred F344; Reference Values; RNA; Spleen; Thymidine | 1989 |
Genetic basis of the association of sulphonamide resistance with methionine auxotrophy in Neisseria gonorrhoeae.
Topics: Bacterial Proteins; Dihydropteroate Synthase; Drug Resistance, Microbial; Folic Acid; Genes, Bacterial; Methionine; Neisseria gonorrhoeae; Phenotype; Sulfadiazine | 1989 |
The effect of methionine on methotrexate metabolism in rat hepatocytes in monolayer culture.
Topics: Animals; Cells, Cultured; Folic Acid; Glutamates; Glutamic Acid; Hydroxylation; Liver; Male; Methionine; Methotrexate; Rats; Rats, Inbred Lew | 1989 |
Methyl group deficiency: effects on one-carbon unit and folate metabolism.
Topics: Animals; Choline Deficiency; Folic Acid; Glycine N-Methyltransferase; Methionine; Methylation; Methyltransferases; Oxidation-Reduction; Rats | 1989 |
Effect of dietary methyl group deficiency on folate metabolism in rats.
Topics: Amino Acids; Animals; Choline Deficiency; Chromatography, High Pressure Liquid; Diet; Folic Acid; Leucovorin; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; Tetrahydrofolates | 1989 |
Effects of nitrous oxide inactivation of vitamin B12 and of methionine on folate coenzyme metabolism in rat liver, kidney, brain, small intestine and bone marrow.
Topics: Animals; Bone Marrow; Brain; Folic Acid; Intestine, Small; Kidney; Liver; Male; Methionine; Nitrous Oxide; Organ Specificity; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12 | 1989 |
Cobalamin inactivation decreases purine and methionine synthesis in cultured lymphoblasts.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Folic Acid; Humans; Lymphocytes; Methionine; Methylmalonyl-CoA Mutase; Nitrous Oxide; Purines; Serine; Vitamin B 12 | 1985 |
Muscle creatine content in rats given repeated large doses of nicotinamide: effects of dietary methionine, choline, carnitine, and other supplements.
Topics: Animals; Carnitine; Choline; Creatine; Diet; Folic Acid; Food, Fortified; Histidine; Male; Methionine; Muscles; Niacinamide; Rats; Rats, Inbred Strains; Vitamin B 12 | 1986 |
Cobalamin inactivation decreases purine and methionine synthesis in cultured human lymphoblasts.
Topics: Folic Acid; Homocysteine; Humans; Lymphocytes; Methionine; Nitrous Oxide; Oxidation-Reduction; Purines; Serine; Vitamin B 12 | 1986 |
Tissue folates in fruit bats (Rousettus aegyptiacus) with nitrous oxide-induced vitamin B12 deficiency and neurological impairment.
Topics: Animals; Brain; Chiroptera; Folic Acid; Liver; Methionine; Nervous System Diseases; Nitrous Oxide; Serine; Vitamin B 12 Deficiency | 1987 |
Demyelination and decreased S-adenosylmethionine in 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Biogenic Amines; Biopterins; Child, Preschool; Female; Folic Acid; Humans; Infant; Infant, Newborn; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Myelin Sheath; Oxidoreductases; S-Adenosylmethionine | 1988 |
Folic acid lowers elevated plasma homocysteine in chronic renal insufficiency: possible implications for prevention of vascular disease.
Topics: Adult; Creatinine; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Middle Aged; Vascular Diseases | 1988 |
Homocysteine and myocardial infarction.
Topics: Cystathionine beta-Synthase; Folic Acid; Heterozygote; Homocystine; Humans; Male; Methionine; Middle Aged; Myocardial Infarction; Retrospective Studies; Risk Factors; Vitamin B 12 | 1988 |
Esophageal cancer: vitamin and lipotrope deficiencies in an at-risk South African population.
Topics: Avitaminosis; Esophageal Neoplasms; Female; Folic Acid; Humans; Male; Methionine; Nutritional Status; Risk Factors; South Africa; Vitamin A; Vitamin B 12; Vitamin E | 1987 |
Growth and DNA synthesis of folate- and methionine-depleted L1210 mouse leukemia cells in culture.
Topics: Animals; Cell Division; Cells, Cultured; Deoxyuridine; DNA; Folic Acid; Leucovorin; Leukemia L1210; Methionine; Mice | 1987 |
The role of folylpolyglutamate synthetase and gamma-glutamyl hydrolase in altering cellular folyl- and antifolylpolyglutamates.
Topics: Animals; Cysteine Endopeptidases; Folic Acid; gamma-Glutamyl Hydrolase; Liver; Liver Neoplasms, Experimental; Male; Methionine; Methotrexate; Peptide Synthases; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Lew | 1987 |
Critical review of cobalamin-folate interrelations.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alcohol Oxidoreductases; Folic Acid; Homocystine; Humans; Infant; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12 | 1986 |
Role of vitamin B12 and folate deficiencies in carcinogenesis.
Topics: Animals; Carcinogens; Diet; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Neoplasms; Neoplasms, Experimental; Vitamin B 12 Deficiency | 1986 |
[An explanation of the metabolic relation of vitamin B12, folates and methionine using oxidative transmethylase].
Topics: Animals; Folic Acid; Humans; Methionine; Models, Chemical; Tetrahydrofolates; Vitamin B 12 | 1986 |
Folic acid responsive rages, seizures and homocystinuria.
Topics: Anger; Child Behavior Disorders; Female; Folic Acid; Homocystinuria; Humans; Male; Methionine; Rage; Seizures | 1985 |
Folic acid responsive postmenopausal homocysteinemia.
Topics: Adult; Aging; Cystine; Dipeptides; Fasting; Female; Folic Acid; Glycine; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Serine | 1985 |
Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients.
Topics: Adolescent; Adult; Betaine; Child; Cystathionine beta-Synthase; Cysteine; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydro-Lyases; Male; Methionine; Middle Aged; Pyridoxine; Serine | 1985 |
Congenital folate malabsorption.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Biological Transport; Blood-Brain Barrier; Brain Diseases; Calcinosis; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Infections; Intellectual Disability; Intestinal Absorption; Methionine; Seizures | 1985 |
A comparison of the response of woodchucks and rats to variations in dietary lipotrope and lipid content.
Topics: Animals; Blood Cell Count; Body Weight; Choline; Diet; Dietary Fats; Folic Acid; Liver; Liver Function Tests; Male; Marmota; Methionine; Organ Size; Rats; Rats, Inbred F344; Sciuridae; Vitamin B 12 | 1985 |
Ethanol, the choline requirement, methylation and liver injury.
Topics: Animals; Betaine; Choline; Ethanol; Folic Acid; Homocysteine; Liver; Methionine; Methylation; Rats; Tetrahydrofolates | 1985 |
[Treatment of patients with chronic liver diseases with a hepatotrophic preparation].
Topics: Bilirubin; Cholinesterases; Chronic Disease; Folic Acid; gamma-Globulins; Hepatitis; Humans; Liver Cirrhosis; Methionine; Niacinamide; Nucleosides; Riboflavin; Serum Albumin; Vitamin B 12 | 1971 |
New light on pernicious anaemia.
Topics: Adolescent; Anemia, Pernicious; Biological Transport; Child, Preschool; Coenzymes; Folic Acid; Hematopoiesis; Humans; Infant, Newborn; Methionine; Methyltransferases; Succinates; Tetrahydrofolates; Vitamin B 12 Deficiency | 1973 |
Folate deficiency and formiminoglutamic acid excretion during chronic diethylnitrosamine administration to rats.
Topics: Animals; Betaine; Carcinogens; Choline; Diet; Drinking; FIGLU Test; Folic Acid; Folic Acid Deficiency; Glutamates; Histidine; Liver; Male; Methionine; Nitrosamines; Rats; Stimulation, Chemical; Transferases; Urocanate Hydratase; Vitamin B 12 | 1973 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on liver constituents associated with folate metabolism.
Topics: Adenosine Triphosphate; Animals; Azo Compounds; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Enterococcus faecalis; Female; FIGLU Test; Folic Acid; Glutarates; Lacticaseibacillus casei; Liver; Methionine; NAD; NADP; Pediococcus; Potassium; Sheep; Sodium; Tetrahydrofolates; Vitamin B 12 Deficiency | 1974 |
Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Female; Folic Acid; Homocysteine; Liver; Membranes; Methionine; Methotrexate; Methyltransferases; NAD; NADP; S-Adenosylmethionine; Serum Albumin, Bovine; Sheep; Tetrahydrofolate Dehydrogenase; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Influence of short-term alcohol consumption on the excretion of some components of the vitamin-B group in the urine of rats.
Topics: Alcoholism; Animals; Biological Assay; Biotin; Choline; Ethanol; Feces; Female; Fluorometry; Folic Acid; Humans; Lipotropic Agents; Male; Methionine; Niacinamide; Nicotinic Acids; Pantothenic Acid; Pyridoxine; Rats; Thiamine; Vitamin B Complex | 1967 |
[Folic acid deficiencies. Etiology and biological diagnosis].
Topics: Alcoholic Intoxication; Anticonvulsants; Antimetabolites; Celiac Disease; Chromatography; Enterococcus faecalis; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Jejunum; Lactobacillus; Liver Cirrhosis; Malabsorption Syndromes; Methionine; Methods; Nucleic Acids; Nutrition Disorders; Polarography; Pregnancy; Scleroderma, Systemic; Serine; Whipple Disease | 1968 |
[Activity of methionine synthetase (5-methyl-5,6,7,8-tetrahydrofolate: homocysteine methyltransferase) as a proliferation parameter in growing cells].
Topics: Cell Division; Cells, Cultured; Cytarabine; DNA Nucleotidyltransferases; Folic Acid; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methionine; Methyltransferases; Prednisolone; Tetrahydrofolates; Thioguanine; Thymidine Kinase; Vincristine | 1973 |
Regulation of C metabolism by L-methionine in Saccharomyces cerevisiae.
Topics: Alcohol Oxidoreductases; Biological Assay; Carbon Isotopes; Cells, Cultured; Chromatography, DEAE-Cellulose; Culture Media; Folic Acid; Formates; Lacticaseibacillus casei; Ligases; Methionine; Methylation; Pediococcus; S-Adenosylmethionine; Saccharomyces cerevisiae; Serine; Tetrahydrofolates; Transferases | 1972 |
The turnover of folate coenzymes in murine lymphoma cells.
Topics: Animals; Biological Assay; Carbon Isotopes; Cell Line; Chromatography, Ion Exchange; Coenzymes; Culture Media; Drug Stability; Folic Acid; Glutamates; Lacticaseibacillus casei; Lymphoma; Methionine; Methotrexate; Mice; Neoplasms, Experimental; Pancreas; Peptides; Protein Binding; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymine Nucleotides; Tritium | 1973 |
NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aspartic Acid; Autoanalysis; Bacterial Proteins; Cell-Free System; Culture Media; Dinitrophenols; Enterococcus faecalis; Folic Acid; Glutamates; Glycine; Methionine; Ribosomes; Serine; Solubility; Threonine | 1973 |
Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R. Biochemical and biophysical properties of methionine transfer ribonucleic acid.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Proteins; Circular Dichroism; Clostridium; Enterococcus faecalis; Escherichia coli; Folic Acid; Formates; Liver; Methionine; Peptide Chain Initiation, Translational; Ribosomes; RNA, Bacterial; RNA, Transfer; Saccharomyces; Sodium; Species Specificity; Structure-Activity Relationship; Transfer RNA Aminoacylation | 1974 |
Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R: partial purification and properties of methionyl-transfer ribonucleic acid synthetase and methionyl-transfer ribonucleic acid formyltransferase.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Bacterial Proteins; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enterococcus faecalis; Folic Acid; Formates; Magnesium; Methionine; Molecular Weight; Mutation; RNA, Transfer; Tetrahydrofolates; Transferases | 1974 |
Partial nucleotide sequence of a prokaryote initiator tRNA that functions in its non-formylated form.
Topics: Autoradiography; Bacterial Proteins; Base Sequence; Electrophoresis; Enterococcus faecalis; Folic Acid; Methionine; Nucleotides; Peptide Chain Initiation, Translational; Polynucleotides; RNA, Transfer; Uracil | 1974 |
Factors involved in the synthesis of cyclopropane fatty acids by Streptococcus faecalis.
Topics: Carbon Radioisotopes; Cell Division; Chromatography, Gas; Cyclopropanes; Enterococcus faecalis; Fatty Acids; Folic Acid; Hydrogen-Ion Concentration; Methionine; Methotrexate; Nephelometry and Turbidimetry; Oleic Acids; Temperature; Thymidine; Time Factors | 1974 |
The activity of some enzymes of folic acid metabolism in the mouse liver during acute liver injury.
Topics: Animals; Ectromelia virus; Folic Acid; Hepatitis A; Liver; Methionine; Methods; Mice; Purines; Tetrahydrofolate Dehydrogenase | 1968 |
[A new hepatoprotective preparation. Biochemical aspects and clinical studies].
Topics: Adult; Aged; Animals; Biopsy; Drug Synergism; Female; Folic Acid; Humans; Liver; Liver Diseases; Male; Methionine; Mice; Middle Aged; Niacinamide; Nucleosides; Nucleotides; Rats; Vitamin B 12 | 1968 |
[Behavior of Shigella flexneri F6S and certain of its mutants in synthetic medium].
Topics: Amino Acids; Culture Media; Cysteine; Cystine; Folic Acid; Genetics, Microbial; Growth Substances; Methionine; Mutation; Niacinamide; Serine; Shigella; Temperature; Thiamine; Vitamin B 12 | 1971 |
Protein chain initiation by methionyl transfer ribonucleic acid in the cytoplasm of Neurospora.
Topics: Acyltransferases; Amino Acyl-tRNA Synthetases; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Cytoplasm; Folic Acid; Formates; Ligases; Methionine; Neurospora; Neurospora crassa; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Polynucleotides; Ribosomes; RNA, Transfer; Tritium | 1971 |
[Clinico-therapeutic evaluation of a new drug combination with hepatotrophic effect].
Topics: Adenine; Adult; Child; Drug Combinations; Folic Acid; Hepatitis A; Humans; Hydroxocobalamin; Inosine; Liver Diseases; Methionine; Middle Aged; Niacinamide; Nucleosides; Riboflavin; Vitamin B 12 | 1972 |
A study of the behavioral disruption of mice induced by l-methionine and related compounds.
Topics: Amphetamine; Animals; Behavior, Animal; Betaine; Chlorpromazine; Cystathionine; Folic Acid; Histidine; Homocysteine; Homoserine; Male; Mescaline; Methionine; Mice; N,N-Dimethyltryptamine; Niacinamide; Serine; Social Behavior | 1974 |
Simple nutrition of Crithidia deanei, a reduviid trypanosomatid with an endosymbiont.
Topics: Biotin; Culture Media; Eukaryota; Folic Acid; Fructose; Glucose; Hemiptera; Mannose; Methionine; Niacinamide; Rickettsiaceae; Sucrose; Thiamine; Tyrosine | 1974 |
Methyl derivatives of folic acid as intermediates in the methylation of homocysteine by Escherichia coli.
Topics: Alkylation; Chromatography; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; In Vitro Techniques; Methionine; Molecular Biology; Mutation; NAD | 1964 |
Influence of vitamin B12 and methionine on levels of folic acid compounds and folate enzymes in rat liver.
Topics: Animals; Biological Assay; Female; Folic Acid; Liver; Methionine; NAD; Oxidoreductases; Pregnancy; Pregnancy, Animal; Rats; Transferases; Vitamin B 12 | 1967 |
Methionine biosynthesis in Ochromonas malhamensis.
Topics: Adenosine Triphosphate; Alcohols; Carbon Isotopes; Cyanides; Enzyme Activation; Eukaryota; Flavin Mononucleotide; Folic Acid; Homocysteine; Kinetics; Light; Magnesium; Methionine; NAD; Oxygen; Sulfur; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B cobalamin methyltransferase: ability of diaphorases and lipoamide dehydrogenases to function as reducing agents.
Topics: Alcohols; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Iodoacetates; Methionine; Methylation; Myocardium; NAD; Spectrophotometry; Sulfhydryl Compounds; Swine; Transferases; Vitamin B 12 | 1970 |
Formation of the N5-methyltetrahydrofolate-homocysteine methyltransferase holoenzyme from apoenzyme and adenosyl-B 12.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Enzyme Precursors; Escherichia coli; Folic Acid; Homocysteine; Methionine; NAD; Transferases; Vitamin B 12 | 1970 |
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12 | 1973 |
Effects of x-irradiation on the various enzymic functions of NADP plus-linked isocitrate dehydrogenase.
Topics: Animals; Benzoates; Catalysis; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Ethylmaleimide; Folic Acid; Glyoxylates; Iodoacetates; Isocitrate Dehydrogenase; Kinetics; Linoleic Acids; Manganese; Methionine; Myocardium; NADP; Oxaloacetates; Peroxides; Radiation Effects; Sulfhydryl Compounds; Sulfides; Swine; Tritium | 1971 |
Urinary excretion of 5-methyltetrahydrofolate and liver S-adenosylmethionine levels of rats fed a vitamin B 12-deficient diet.
Topics: Animals; Bacteria; Biological Assay; Biological Transport; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Drug Stability; Ethionine; Folic Acid; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Tetrahydrofolates; Time Factors; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
The effect of DL-methionine, vitamin B 12, and thyroid powder on metabolism of formiminoglutamic acid in rats.
Topics: Animals; Azo Compounds; Body Weight; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Glutarates; Growth; Homocysteine; Liver; Male; Methionine; Methods; Rats; Tetrahydrofolates; Thyroid (USP); Thyroid Hormones; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Regulation of 5-methyltetrahydrofolate: homocysteine methyltransferase activity by methionine, vitamin B12, and folate in cultured baby hamster kidney cells.
Topics: Animals; Cells, Cultured; Cricetinae; Folic Acid; Homocysteine; Kidney; Mercaptoethanol; Methionine; Methyltransferases; Puromycin; Tetrahydrofolates; Vitamin B 12 | 1973 |
The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture.
Topics: Animals; Breast; Carcinoma 256, Walker; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Culture Media; Female; Fibroblasts; Folic Acid; Homocystine; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid; Liver; Male; Methionine; Mice; Prostate; Rats; Vitamin B 12 | 1974 |
[Suppression of cytostatic effect of amethopterin (methotrexate) with methyltetrahydrofolic acid].
Topics: Cells, Cultured; Folic Acid; Humans; Leukemia, Myeloid; Lymphocytes; Methionine; Methotrexate; Methyltransferases; Tetrahydrofolates | 1974 |
A patient with nonketotic hyperglycinemia: biochemical findings and therapeutic approaches.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Benzoates; Biopsy; Carbon Radioisotopes; Child, Preschool; Choline; Diet Therapy; Electroencephalography; Female; Folic Acid; Glycine; Humans; Infant; Infant, Newborn; Leucovorin; Liver; Methionine; Pyridoxine; Salicylates; Tetrahydrofolates | 1974 |
Studies on the regulation of one-carbon metabolism. II. Repression-derepression of serine hydroxymethyltransferase by methionine in Escherichia coli 113-3.
Topics: Ammonium Sulfate; Chemical Precipitation; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Repression; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Methionine; Methyltransferases; Molecular Weight; Oxidoreductases; S-Adenosylmethionine; Serine; Tetrahydrofolate Dehydrogenase; Thymine Nucleotides; Transferases; Uracil Nucleotides; Vitamin B 12 | 1972 |
Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12.
Topics: Adenosine Triphosphate; Culture Media; Cystathionine; Enzyme Repression; Escherichia coli; Folic Acid; Homocysteine; Hydro-Lyases; L-Serine Dehydratase; Methionine; Methyltransferases; Mutation; Oxidoreductases; S-Adenosylmethionine; Time Factors; Transferases; Vitamin B 12 | 1973 |
Kinetics of derepression of the tryptophan operon of Escherichia coli and Salmonella typhimurium under different culture conditions.
Topics: Aniline Compounds; Anthranilate Synthase; Culture Media; Enzyme Repression; Escherichia coli; Folic Acid; Genes, Regulator; Histidine; Kinetics; Methionine; Nucleic Acid Hybridization; Operon; Peptide Biosynthesis; RNA, Bacterial; RNA, Messenger; Salmonella typhimurium; Sulfur Radioisotopes; Temperature; Thiazoles; Trimethoprim; Tritium; Tryptophan; Tryptophan Synthase | 1973 |
Studies on the influence of biotin on folate metabolism in Escherichia coli B.
Topics: Biotin; Carboxypeptidases; Chromatography; Escherichia coli; Folic Acid; Glutamates; Methionine; Tetrahydrofolates | 1974 |
[Effect of combined trimethoprim-sulfamethoxazole on level of folates in blood].
Topics: Anti-Bacterial Agents; Biological Assay; Drug Combinations; Drug Synergism; Erythrocytes; Evaluation Studies as Topic; Fever; Folic Acid; Folic Acid Antagonists; Humans; Lacticaseibacillus casei; Methionine; Pyrimidines; Sulfamethoxazole; Time Factors; Trimethoprim; Vitamin B 12 | 1972 |
Folic acid and the methylation of homocysteine by Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Bacillus subtilis; Chromatography, Gel; Chromatography, Thin Layer; Cobamides; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Ultrasonics; Vitamin B 12 | 1972 |
Methionine transfer ribonucleic acid from folate-sufficient and folate-deficient Streptococcus faecalis R.
Topics: Acylation; Amino Acids; Amino Acyl-tRNA Synthetases; Ammonia; Carbon Isotopes; Chromatography, DEAE-Cellulose; Culture Media; Electrophoresis, Paper; Enterococcus faecalis; Escherichia coli; Folic Acid; Formates; Hydrolysis; Kinetics; Leucovorin; Methionine; Pancreas; Ribonucleases; RNA, Transfer; Salmonella typhimurium; Sulfur Isotopes; Tritium | 1972 |
Homocystinuria. Reduced folate levels during pyridoxine treatment.
Topics: Child; Child, Preschool; Cystine; Erythrocytes; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Infant; Male; Metabolic Diseases; Methionine; Methyltransferases; Pyridoxine | 1973 |
Folate activity of human lymphocytes determined by measurement of serine synthesis.
Topics: Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Citric Acid Cycle; Folic Acid; Folic Acid Deficiency; Formates; Glucose; Glycine; Humans; In Vitro Techniques; Lymphocytes; Methionine; Methods; Protein Binding; Pyridoxal Phosphate; RNA; Serine; Tetrahydrofolates | 1973 |
Effect of methionine on specific folate coenzyme pools in vitamin B 12 deficient and supplemented rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Carbon Isotopes; Chromatography, DEAE-Cellulose; Coenzymes; FIGLU Test; Folic Acid; Glutamates; Homocysteine; Liver; Male; Malonates; Methionine; Methyltransferases; Oligopeptides; Rats; Tetrahydrofolates; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
Schildt B, Sörbo B,+SORBO B:Studies on the biosynthesis and transfer of labile methyl groups in experimental burns.
Topics: Animals; Burns; Choline; Folic Acid; Liver; Methionine; Methylation; Mice; Vitamin B 12 | 1973 |
[Importance and regulation of the cobalamin-dependent methionine synthetase and the betaine: homocystein methyltransferase in methionine and tetrahydrofolic acid metabolism of the rat].
Topics: Animals; Betaine; Coenzyme A; Diet; Female; Folic Acid; Homocysteine; Kidney; Liver; Methionine; Methylation; Methyltransferases; Rats; Tetrahydrofolates; Vitamin B 12 | 1973 |
Folated deficiency in pernicious anemia measured by determination of decreased serine synthesis in lymphocytes.
Topics: Adolescent; Adult; Aged; Anemia, Pernicious; Blood Proteins; Carbon Isotopes; Female; Folic Acid; Folic Acid Deficiency; Formates; Humans; Lymphocytes; Male; Methionine; Methods; Middle Aged; RNA; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
Pregnancy and homocystinuria.
Topics: Adult; Amnion; Blood Coagulation Tests; Cell Line; Cystine; Female; Fibroblasts; Folic Acid; Homocystine; Homocystinuria; Humans; L-Serine Dehydratase; Methionine; Pregnancy; Pregnancy Complications; Pyridoxine; Vitamin B 12 | 1973 |
Dependence of 5-methyltetrahydrofolate utilization by L5178Y murine leukemia cells in vitro on the presence of hydroxycobalamin and transcobalamin II.
Topics: Animals; Cell Division; Cobalt Isotopes; Coenzymes; Culture Techniques; Folic Acid; Leukemia, Experimental; Methionine; Mice; Tetrahydrofolates; Time Factors; Vitamin B 12 | 1973 |
Mechanism of decrease in serum folate levels of rats receiving diphenylhydantoin.
Topics: Animals; Blood Proteins; Folic Acid; Liver; Male; Methionine; Methyltransferases; Phenytoin; Protein Binding; Rats; Tetrahydrofolates; Vitamin B 12 | 1973 |
Folic acid deficiency and methyl group metabolism in rat brain: effects of L-dopa.
Topics: Animals; Body Weight; Brain; Dihydroxyphenylalanine; Folic Acid; Folic Acid Deficiency; Kidney; Liver; Male; Methionine; Organ Size; Organ Specificity; Rats; S-Adenosylmethionine; Time Factors; Vitamin B 12 | 1974 |
Investigations of coagulation and fibrinolysis in homocystinuria.
Topics: Adult; Blood Coagulation; Cystine; Diet; Factor V; Female; Fibrinogen; Fibrinolysis; Folic Acid; Homocystine; Homocystinuria; Humans; Methionine; Platelet Adhesiveness; Pyridoxine | 1974 |
Enzymic synthesis of methionine: formation of a radioactive cobamide enzyme with N5-methyl-14C-tetrahydrofolate.
Topics: Carbon Isotopes; Catalysis; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Kinetics; Methionine; Methylation; Transferases; Vitamin B 12 | 1967 |
Unusual growth characteristics of a methionine-cyano-B12 auxotroph of Escherichia coli.
Topics: Adenine; Alcohol Oxidoreductases; Arginine; Carbon Isotopes; Escherichia coli; Folic Acid; Histidine; Ligases; Methionine; Mutation; Nucleosides; Oxidoreductases; Thiamine; Transferases; Vitamin B 12 | 1967 |
Chemical propylation of vitamin-B12 transmethylase: anomalous behavior of S-adenosyl-L-methionine.
Topics: Adenine Nucleotides; Alkylation; Carbon Isotopes; Escherichia coli; Flavins; Folic Acid; Homocysteine; Methionine; Models, Chemical; Serum Albumin, Bovine; Sulfhydryl Compounds; Transferases; Vitamin B 12 | 1968 |
Characterization of two species of methionine transfer ribonucleic acid from bakers' yeast.
Topics: Carbon Isotopes; Cell-Free System; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Coliphages; Dextrans; Escherichia coli; Folic Acid; Ligases; Methionine; Peptide Biosynthesis; Protein Biosynthesis; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; RNA, Viral; Saccharomyces; Spectrophotometry; Transferases; Viral Proteins | 1968 |
Binding of substrate to N5-methyl-tetrahydroteroyl-triglutamate-homocysteine transmethylase.
Topics: Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Escherichia coli; Folic Acid; Gels; Homocysteine; Methionine; Transferases | 1968 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine methyltransferase: sequential formation of bound methylcobalamin with S-adenosyl-L-methionine and N5-methyltetrahydrofolate.
Topics: Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Escherichia coli; Folic Acid; Homocysteine; Light; Methionine; Methylation; Nucleosides; Temperature; Time Factors; Transferases; Vitamin B 12 | 1969 |
Escherichia coli B N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: activation with S-adenosyl-L-methionine and the mechanism for methyl group transfer.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Models, Biological; Nucleosides; Time Factors; Transferases; Vitamin B 12 | 1969 |
Protein initiation without folate in Streptococcus faecium.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbon Isotopes; Escherichia coli; Folic Acid; Folic Acid Antagonists; Formates; Methionine; Pyrimidines; RNA, Transfer; Streptococcus; Sulfur Isotopes | 1969 |
Virus-specific proteins in Escherichia coli infected with the RNA bacteriophage MS2.
Topics: Bacterial Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Coliphages; Dactinomycin; Detergents; Electrophoresis; Escherichia coli; Eukaryota; Folic Acid; Genetic Code; Histidine; Kinetics; Leucine; Methionine; Molecular Weight; Peptides; Protoplasts; RNA, Viral; Tritium; Uracil; Viral Proteins; Virus Replication | 1968 |
The substrate specificity of 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase.
Topics: Escherichia coli; Folic Acid; Glutamates; Homocysteine; Methionine; Methylation; Neurospora; Saccharomyces; Transferases | 1969 |
The initiation of T4 deoxyribonucleic acid-dependent beta-glucosyltransferase synthesis in vitro.
Topics: Coliphages; DNA, Viral; Escherichia coli; Folic Acid; Formates; Glucosyltransferases; Leucovorin; Magnesium; Methionine; Ribosomes; RNA, Bacterial; RNA, Transfer; Stimulation, Chemical; Templates, Genetic; Tritium; Viral Proteins | 1969 |
On the role of S-adenoxylmethionine in the vitamin B12 dependent methionine biosynthesis.
Topics: Alcohols; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Escherichia coli; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxyapatites; Kinetics; Methionine; Methods; Methylation; Nucleosides; Spectrophotometry; Sulfur; Transferases; Vitamin B 12 | 1969 |
Purification and properties of 5-methyltetrahydropteroyltriglutamate-homocysteine transmethylase.
Topics: Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Culture Media; Electrophoresis, Disc; Enzyme Repression; Escherichia coli; Folic Acid; Homocysteine; Magnesium; Mathematics; Methionine; Methods; Molecular Weight; Mutation; Peptides; Protamines; Quaternary Ammonium Compounds; Spectrophotometry; Transferases; Ultracentrifugation; Ultraviolet Rays; Vibration | 1970 |
Aminoacyl formylmethionyl transfer ribonucleic acid transformylase. Inhibitor studies and the reversal of the reaction.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Escherichia coli; Folic Acid; Formates; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Methionine; Pteridines; RNA, Transfer; Transferases; Tritium | 1970 |
Escherichia coli B 5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: catalysis by a reconstituted methyl-14C-cobalamin holoenzyme and the function of S-adenosyl-l-methionine.
Topics: Carbon Isotopes; Escherichia coli; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydrogen; Kinetics; Methionine; Nucleosides; Oxygen; Protein Binding; Transferases; Vitamin B 12 | 1970 |
Spectrophotometric evidence for the formation of an Escherichia coli B B-12s methyltransferase.
Topics: Alcohols; Carbon Isotopes; Escherichia coli; Folic Acid; Free Radicals; Homocysteine; Hydrogen-Ion Concentration; Iodides; Ligases; Methionine; Methylation; Oxidation-Reduction; Spectrophotometry; Sulfur; Transferases; Ultraviolet Rays; Vitamin B 12 | 1970 |
Methionine synthetase. Existence and interconversion of two enzyme species.
Topics: Chromatography, Gel; Escherichia coli; Folic Acid; Macromolecular Substances; Methionine; Molecular Weight; Nucleosides; Spectrum Analysis; Time Factors; Transferases | 1970 |
Inhibition of peptide chain initiation in Escherichia coli by hydroxylamine. Reaction of hydroxylamine with folate coenzymes.
Topics: Chemical Phenomena; Chemistry; Escherichia coli; Folic Acid; Folic Acid Antagonists; Formates; Hydroxylamines; Methionine; Methylation; Oxidoreductases; Oximes; Peptide Biosynthesis; RNA, Transfer; Spectrophotometry; Transferases; Uracil Nucleotides | 1970 |
Studies on the ability of norleucine to replace methionine in the initiation of protein synthesis of E. coli.
Topics: Bacterial Proteins; Caproates; Carbon Isotopes; Electrophoresis; Enzyme Repression; Escherichia coli; Folic Acid; Formates; Hydro-Lyases; Methionine; Oxidoreductases; Puromycin; Ribosomes; RNA, Transfer; Transferases | 1970 |
Evidence for the requirement of methionyl tRNA modification for in vitro polypeptide initiation in Streptococcus faecium.
Topics: Acylation; Acyltransferases; Bacterial Proteins; Binding Sites; Cell-Free System; Deoxyribonucleases; Escherichia coli; Folic Acid; Formates; Magnesium; Methionine; Peptide Biosynthesis; Polynucleotides; Puromycin; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Spermine; Streptococcus; Sulfur Isotopes | 1971 |
The vitamin B12-dependent methionine synthetase. The cycle of transmethylation.
Topics: Enzyme Induction; Escherichia coli; Folic Acid; Homocysteine; Methionine; Methylation; Methyltransferases; Nucleosides; Oxidation-Reduction; Spectrophotometry; Transferases; Vitamin B 12 | 1971 |
Vitamin B 12 and methionine synthesis in Escherichia coli.
Topics: Acyltransferases; Aerobiosis; Alcohol Oxidoreductases; Anilides; Carbon Isotopes; Chromatography, Ion Exchange; Enzyme Repression; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Genetics, Microbial; Homocysteine; Homoserine; Kinetics; Methionine; Methyltransferases; Mutation; Serine; Succinates; Transferases; Vitamin B 12 | 1971 |
Biosynthesis of methionine by bacteria.
Topics: Enterococcus faecalis; Folic Acid; Methionine | 1966 |
Folate coenzyme pattern, folate linked enzymes and methionine biosynthesis in rat liver mitochondria.
Topics: Alcohol Oxidoreductases; Animals; Cellulose; Coenzymes; Enterococcus faecalis; Folic Acid; Ion Exchange Resins; Kidney; Lactobacillus; Ligases; Liver; Methionine; Mitochondria; Oxidoreductases; Pediococcus; Rats; Swine; Transferases | 1967 |
Biosynthesis of folic acid. I. Influence of various heterocyclic metabolites on the biogenesis of folic acid in microorganisms.
Topics: Culture Media; Enterococcus faecalis; Escherichia coli; Euglena; Folic Acid; Lactobacillus; Methionine; Pantothenic Acid; Riboflavin; Thymine; Vitamin B 12 | 1966 |
Tetrahydrofolate-dependent enzyme activities of the rat liver in riboflavin deficiency.
Topics: Animals; Centrifugation; Chromatography, Thin Layer; Enterococcus faecalis; FIGLU Test; Folic Acid; Formates; Histidine; Hydrogen-Ion Concentration; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Lactobacillus; Liver; Male; Methionine; Pediococcus; Potassium; Rats; Riboflavin; Riboflavin Deficiency; Serine; Tetrahydrofolate Dehydrogenase; Transferases | 1968 |
Metabolism of S-adenosylmethionine in germinating pea seeds: turnover and possible relationships between recycling of sulfur and transmethylation reactions.
Topics: Biological Assay; Carbon Isotopes; Cell-Free System; Chromatography, Thin Layer; Enterococcus faecalis; Folic Acid; Homocystine; Kinetics; Methionine; Methylation; Models, Biological; Nucleosides; Sulfur; Sulfur Isotopes; Tritium | 1969 |
Effects of dietary methionine and vitamin B12 deficiency on folate metabolism.
Topics: Animals; Biological Assay; Deficiency Diseases; Diet; Electrophoresis; Enterococcus faecalis; Folic Acid; Hematocrit; Hemoglobinometry; Lactobacillus; Liver; Male; Methionine; Nitrogen; Radioisotopes; Rats; Transferases; Vitamin B 12 | 1969 |
Incorporation of N-formylmethionine into peptides by Pseudomonas aeruginosa extracts.
Topics: Adenosine Triphosphate; Amino Acids; Carbon Isotopes; Cell-Free System; Chloramphenicol; Chromatography; Electrophoresis; Folic Acid; Formates; Magnesium; Methionine; Paper; Peptide Biosynthesis; Pseudomonas aeruginosa; Puromycin; Quaternary Ammonium Compounds; Reticulocytes; Ribonucleases; RNA, Transfer; Transferases; Tritium | 1970 |
Homocysteine-dependent transmethylases catalyzing the synthesis of methionine in germinating pea seeds.
Topics: Chromatography, Gel; Edetic Acid; Folic Acid; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Methionine; Neurospora; Nucleosides; Plants; Saccharomyces; Seeds; Transferases | 1970 |
The amino-terminal residues of Bacillus subtilis proteins made in vitro.
Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Cell-Free System; Chromatography, Gel; Folic Acid; Formates; Kinetics; Methionine; Molecular Weight; Peptide Biosynthesis; Peptide Hydrolases; RNA, Messenger; Serine; Threonine; Tritium; Valine | 1970 |
[Biological role of vitamin B 12: analysis of strict vitamin requirement of cell line of insects in vitro].
Topics: Aminopterin; Cell Division; Cell Line; Coleoptera; Culture Techniques; Folic Acid; Folic Acid Deficiency; Methionine; Nucleic Acids; Nucleotides; Purines; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Evidence against the folate-mediated formylation of formyl-accepting methionyl transfer ribonucleic acid in Streptococcus faecalis R.
Topics: Adenine; Aminopterin; Bacterial Proteins; Culture Media; Enterococcus faecalis; Folic Acid; Folic Acid Antagonists; Formates; Guanine; Methionine; Pyrimidines; RNA, Transfer; Serine; Thymine | 1970 |
Total synthesis of acetate from CO 2 : methyltetrahydrofolate, an intermediate, and a procedure for separation of the folates.
Topics: Acetates; Animals; Biological Assay; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Chromatography, Ion Exchange; Clostridium; Culture Media; Electron Transport; Enterococcus faecalis; Enzymes; Folic Acid; Freeze Drying; Glutamates; Homocysteine; Hydrolysis; Kidney; Methionine; Methods; Methyltransferases; Swine | 1971 |
A role for folic acid conjugase in the regulation of methionine synthesis by Coprinus lagopus.
Topics: Bacillus subtilis; Basidiomycota; Carboxypeptidases; Chromatography, Ion Exchange; Chromatography, Thin Layer; Folic Acid; Glutamates; Methionine | 1971 |
Methionine or folate and phosphoenolpyruvate in the biosynthesis of threonine in Crithidia fasciculata.
Topics: Alanine; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Culture Media; Cystine; Eukaryota; Folic Acid; Homocysteine; Homoserine; Hydrazones; Hydroxybutyrates; Keto Acids; Methionine; Methyltransferases; Phosphoenolpyruvate; Sulfonic Acids; Sulfur Isotopes; Threonine | 1972 |
Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity.
Topics: Adolescent; Carbon Isotopes; Coenzymes; Female; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Methionine; Methylation; Methyltransferases; Oxidoreductases; Vitamin B 12 | 1972 |
An assay for N 5 -methyltetrahydrofolate-homocysteine transmethylase activity using instant thin-layer chromatography.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Folic Acid; Formaldehyde; Homocysteine; Kidney; Methionine; Methylation; Methyltransferases; S-Adenosylmethionine | 1972 |
Folate deficiency in malnutrition, malabsorption, and during phenytoin treatment diagnosed by determination of serine synthesis in lymphocytes.
Topics: Adult; Aged; Anemia; Carbon Isotopes; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Lymphocytes; Malabsorption Syndromes; Male; Methionine; Middle Aged; Nutrition Disorders; Phenytoin; Proteins; RNA; Serine; Time Factors | 1972 |
The effect of methionine on folic acid and histidine metabolism in perfused rat liver.
Topics: Animals; Betaine; Carbon Dioxide; Carbon Isotopes; Choline; Deficiency Diseases; Drug Synergism; Ethionine; Folic Acid; Formates; Glutamates; Histidine; Homocysteine; Liver; Male; Methionine; Oxidation-Reduction; Peptides; Perfusion; Rats; Tetrahydrofolates; Vitamin B 12 Deficiency | 1972 |
Homocystinuria, vitamin B 6 , and folate: metabolic interrelationships and clinical significance.
Topics: Alcohol Oxidoreductases; Cystathionine; Folic Acid; Glycine; Homocystine; Homocystinuria; Humans; L-Serine Dehydratase; Metabolic Diseases; Methionine; Methyltransferases; Pyridoxine; Tetrahydrofolates; Transferases; Vitamin B 12 | 1972 |
Combined vitamin responsiveness in homocystinuria.
Topics: Adolescent; Adult; Amino Acids; Child; Drug Synergism; Female; Folic Acid; Folic Acid Deficiency; Glycine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Metabolic Diseases; Methionine; Methylation; Pyridoxine; Vitamin B 12 | 1972 |
Relationship of arginine and methionine to creatine formation in chicks.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Choline Deficiency; Creatine; Cystine; Deficiency Diseases; Depression, Chemical; Folic Acid; Folic Acid Deficiency; Glycine; Glycine max; Guanidines; Lipid Metabolism; Liver; Male; Methionine; Muscles; Ornithine; Stimulation, Chemical; Urea; Vitamin B 12; Vitamin B 12 Deficiency; Zea mays | 1971 |
Mechanism of mammalian cobalamin-dependent methionine biosynthesis.
Topics: Alkylation; Animals; Carbon Isotopes; Darkness; Dithiothreitol; Electrophoresis, Disc; Enzyme Activation; Flavin Mononucleotide; Folic Acid; Homocysteine; Hydroxocobalamin; Iodides; Kidney; Kinetics; Light; Mathematics; Mercaptoethanol; Methionine; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Oxidation-Reduction; Radiation Effects; S-Adenosylmethionine; Swine; Tritium | 1971 |
Mechanism of adenine inhibition in adenine-sensitive mutants of Salmonella typhimurium.
Topics: Adenine; Aminobenzoates; Folic Acid; In Vitro Techniques; Kinetics; Lysine; Methionine; Mutation; Pantothenic Acid; Salmonella typhimurium; Sulfadiazine; Thiamine | 1966 |
Altered folate metabolism in a vitamin B 12-methionine auxotroph.
Topics: Escherichia coli; Folic Acid; Methionine; Molecular Biology; Mutation; Nucleosides; Tetrahydrofolate Dehydrogenase; Transferases; Uridine; Vitamin B 12 | 1964 |
Control of one-carbon metabolism in a methionine-B12 auxotroph of Escherichia coli.
Topics: Carbon; Carbon Isotopes; Enzyme Repression; Escherichia coli; Feedback; Folic Acid; Ligases; Methionine; Mutation; Oxidoreductases; Tetrahydrofolate Dehydrogenase; Thymidine; Transferases; Vitamin B 12 | 1966 |
Involvement of N-formylmethionine in initiation of protein synthesis in cell-free extracts of Euglena gracilis.
Topics: Carbon Isotopes; Chloroplasts; Chromatography, Ion Exchange; Chymotrypsin; Coliphages; Electrophoresis; Escherichia coli; Euglena; Folic Acid; Formates; Methionine; Peptides; Protein Biosynthesis; Ribosomes; RNA, Viral; Tritium | 1967 |
[Pernicious anemia--funicular spinal disease--pernicious psychosis].
Topics: Anemia, Pernicious; Female; Folic Acid; Homocysteine; Humans; Intestinal Absorption; Isomerases; Methionine; Middle Aged; Neurocognitive Disorders; Spinal Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 1969 |
Vitamin B 12 dependent methionine biosynthesis in cultured mammalian cells.
Topics: Animals; Carbon Isotopes; Carcinoma; Cell Division; Cell Line; Cricetinae; Culture Media; Culture Techniques; Drug Synergism; Folic Acid; Formaldehyde; HeLa Cells; Homocysteine; Humans; Kidney; Laryngeal Neoplasms; Methionine; Stimulation, Chemical; Swine; Transferases; Vitamin B 12 | 1969 |
[Inborn error of vitamin B12 metabolism].
Topics: Coenzymes; Folic Acid; Humans; Malonates; Metabolism, Inborn Errors; Methionine; Vitamin B 12 | 1969 |
Recent clinical advances in the treatment of neurological diseases.
Topics: Brain Diseases; Child, Preschool; Chronic Disease; Cystine; Diet Therapy; Dopamine; Folic Acid; Homocystinuria; Humans; Infant; Maple Syrup Urine Disease; Methionine; Movement Disorders; Muscular Diseases; Pyridoxine; Serotonin | 1970 |
Factors affecting formiminoglutamic acid excretion in vitamin B 12 deficiency.
Topics: Aminopterin; Animals; Betaine; Female; Folic Acid; Folic Acid Deficiency; Glutarates; Histidine; Male; Methionine; Rats; Sheep; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Initiation of phi-X-174 RF-primed protein with N-formylmethionine.
Topics: Alanine; Carbon Isotopes; Cell-Free System; Coliphages; Detergents; DNA, Viral; Electrophoresis; Folic Acid; Formates; Gels; Genetic Code; Kinetics; Methionine; Peptide Hydrolases; RNA, Viral; Serine; Sulfuric Acids; Tritium; Viral Proteins | 1970 |
[Variations in the levels of folates, B 12 and methionine in the blood of mothers of hypotrophic and normal children].
Topics: Birth Weight; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methionine; Pregnancy; Vitamin B 12 | 1970 |
Methylcobalamin as an intermediate in mammalian methionine biosynthesis.
Topics: Animals; Carbon Isotopes; Chromatography, Gel; Electrophoresis; Ethanol; Folic Acid; Homocysteine; Kidney; Methionine; Methylation; Nucleosides; Photochemistry; Solubility; Swine; Transferases; Vitamin B 12 | 1970 |
Methylation of homocysteine in Coprinus lagopus.
Topics: Basidiomycota; Folic Acid; Homocysteine; Methionine; Methylation; Serine; Transferases | 1970 |
Hydrocarbon-utilizing microorganism. Relationship of fatty acid composition and biosynthesis to hydrocarbon substrate and to vitamin B 12 level in Corynebacterium simplex.
Topics: Alkanes; Carbon Isotopes; Cobalt; Corynebacterium; Culture Media; Fatty Acids; Folic Acid; Homocysteine; Methionine; Methylation; Nucleosides; Spectrum Analysis; Transferases; Vitamin B 12 | 1970 |
Deranged B 12 metabolism: effects on sulfur amino acid metabolism.
Topics: Adenosine Triphosphate; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Betaine; Brain Chemistry; Carbon Isotopes; Child, Preschool; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Isomerases; Kidney; Liver; Male; Malonates; Methionine; Methyltransferases; Transferases; Vitamin B 12 | 1970 |
Deranged B 12 metabolism: studies of fibroblasts grown in tissue culture.
Topics: Amino Acid Metabolism, Inborn Errors; Carbon Dioxide; Carbon Isotopes; Coenzyme A; Fibroblasts; Folic Acid; Glutamates; Homocysteine; Humans; Hydroxocobalamin; Isomerases; L-Serine Dehydratase; Male; Malonates; Methionine; Methyltransferases; Propionates; Skin; Vitamin B 12 | 1970 |
Homocystinuria with methylmalonic aciduria: two cases in a sibship.
Topics: Adolescent; Carbon Isotopes; Child, Preschool; Coenzyme A; Female; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Isomerases; L-Serine Dehydratase; Male; Malonates; Methionine; Methyltransferases; Pedigree; Propionates; Skin; Vitamin B 12 | 1970 |
A case of homocystinuria with a dystonic neurological syndrome.
Topics: Adolescent; Cystine; Extrapyramidal Tracts; Folic Acid; Homocystine; Homocystinuria; Humans; Male; Methionine; Movement Disorders; Muscle Tonus; Muscular Diseases; Prognosis; Pyridoxine; Taurine | 1970 |
The effect of vitamin B 12 and methionine on folic acid uptake by rat liver.
Topics: Animal Feed; Animals; Folic Acid; Injections, Intravenous; Liver; Methionine; Organ Size; Rats; Tritium; Vitamin B 12 | 1971 |
Studies on vitamin B12 metabolism in HeLa cells.
Topics: Adenosine Triphosphate; Carbon Dioxide; Carbon Isotopes; Cell Line; Coenzyme A; Culture Techniques; Enzyme Activation; Folic Acid; HeLa Cells; Homocysteine; Isomerases; Malonates; Methionine; Propionates; Transferases; Vitamin B 12 | 1971 |
[Role of methionine in hydrochloric acid secretion by the gastric mucosa].
Topics: Animals; Anura; Ascorbic Acid; Folic Acid; Gastric Juice; Gastric Mucosa; Methionine; Vitamin B 12 | 1971 |
New mutant types at the ade3 locus of Saccharomyces cerevisiae.
Topics: Adenine; Alleles; Aminohydrolases; Cell-Free System; Chromosome Mapping; Crosses, Genetic; Culture Media; Diploidy; Folic Acid; Genetic Complementation Test; Genetics, Microbial; Histidine; Indicators and Reagents; Ligases; Methionine; Mutagens; Mutation; Oxidoreductases; Pigments, Biological; Recombination, Genetic; Saccharomyces; Spectrophotometry; Sulfonic Acids | 1971 |
Choline level and its effect on egg weight in the Japanese quail.
Topics: Animal Nutritional Physiological Phenomena; Animals; Biotin; Bird Diseases; Birds; Choline Deficiency; Eggs; Female; Folic Acid; Inositol; Methionine; Nutritional Requirements; Ovulation; Vitamin B 12 | 1971 |
Deranged DNA synthesis by bone marrow from vitamin B-12-deficient humans.
Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; Female; Folic Acid; Folic Acid Deficiency; Humans; In Vitro Techniques; Methionine; Methotrexate; Thymine; Tritium; Uridine; Vitamin B 12; Vitamin B 12 Deficiency | 1968 |
Homocystinuria. II. Subnormal serum folate levels, increased folate clearance and effects of folic acid therapy.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; FIGLU Test; Folic Acid; Homocystine; Homocystinuria; Humans; Intelligence; Male; Methionine; Nitrogen; Vitamin B 12 | 1968 |
Action of sulfanilamide on Ochromonas malhamensis.
Topics: Amino Acids; Aminobenzoates; Animals; Eukaryota; Folic Acid; Methionine; Pterins; Purines; Pyrimidines; Sulfanilamides; Vitamin B 12 | 1968 |
Treatment of homocystinuria with pyridoxine. A preliminary study.
Topics: Adolescent; Adult; Aminobutyrates; Child; Child, Preschool; Cystine; Female; Folic Acid; Folic Acid Deficiency; Homocystine; Homocystinuria; Humans; Hydro-Lyases; Infant; L-Serine Dehydratase; Male; Methionine; Pyridoxine | 1969 |
Increased urinary excretion of 3H-folic acid injected to rats with riboflavin deficiency or excessive dietary methionine.
Topics: Animals; Chromatography; Diet; Folic Acid; Injections, Intramuscular; Male; Methionine; Rats; Riboflavin Deficiency; Time Factors; Tritium | 1969 |
Serum valine and methionine levels in pernicious anaemia under treatment.
Topics: Adult; Aged; Anemia, Pernicious; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Valine; Vitamin B 12 | 1969 |
The formation of methionine from the monoglutamate form of methyltetrahydrofolate by higher plants.
Topics: Acyltransferases; Carbon Isotopes; Chromatography, Gel; Folic Acid; Glutamates; Kinetics; Methionine; Methylation; Nucleosides; Plants; Vitamin B 12 | 1969 |
[Correlations among the amounts of B 12, methionine and folates in the blood of mothers of hypotrophic infants].
Topics: Biological Assay; Birth Weight; Diet; Female; Folic Acid; Genetic Diseases, Inborn; Humans; Infant, Newborn; Lactobacillus; Leuconostoc; Male; Methionine; Nutritional Requirements; Postpartum Period; Pregnancy; Statistics as Topic; Vitamin B 12 | 1969 |
A chromatographically different form of the formyl-accepting methionine transfer RNA from Escherichia coli.
Topics: Carbon Isotopes; Chromatography; Chromatography, Gel; Electrophoresis; Folic Acid; Formates; Methionine; Nucleotides; RNA, Bacterial; RNA, Transfer; Spectrum Analysis; Tritium; Ultracentrifugation | 1969 |
Folic acid involvement in cyclopropane fatty acid synthesis in lactobacilli.
Topics: Acetates; Aminopterin; Carbon Isotopes; Coenzymes; Cyclopropanes; Fatty Acids; Folic Acid; In Vitro Techniques; Lactobacillus; Methionine | 1965 |
Relation of vitamin B12 and one-carbon metabolism to hydrocephalus in the rat.
Topics: Animals; Animals, Newborn; Carbon; Choline; Diet; Folic Acid; Folic Acid Antagonists; Hydrocephalus; Methionine; Rats; Vitamin B 12 Deficiency | 1966 |
The biosynthesis of the methyl groups of choline in Ochromonas malhamensis.
Topics: Alkylation; Amino Alcohols; Choline; Eukaryota; Folic Acid; Homocysteine; In Vitro Techniques; Methionine; Microsomes; Mitochondria; Nucleosides; Phosphatidylcholines; Subcellular Fractions; Vitamin B 12 | 1966 |
Methionine metabolism of the myxomycete Physarum polycephalum.
Topics: Adenine; Amino Acids; Butyrates; Culture Media; Folic Acid; Glycine; Histidine; Methionine; Myxomycetes; Peptides; Sulfur; Vitamin B 12 | 1966 |
Effect of thyroxine on folic acid metabolism.
Topics: Animals; Body Weight; Caseins; FIGLU Test; Folic Acid; Formates; Methionine; Rats; Thyroxine; Vitamin B 12 | 1966 |
Vitamin B12 deficiency in the rat: effect on serum folate and liver formiminotransferase activity.
Topics: Aldehyde-Lyases; Animals; Biological Assay; Choline; Folic Acid; Glutamates; Liver; Male; Methionine; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1967 |
Feedback inhibition of methylene-tetrahydrofolate reductase in rat liver by S-adenosylmethionine.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Buffers; Carbon Isotopes; Centrifugation; Enzymes; Feedback; Folic Acid; Homocysteine; Liver; Methionine; Rats | 1967 |
Origin of photolabile methyl groups in methionine biosynthesis.
Topics: Alkylation; Animals; Folic Acid; In Vitro Techniques; Light; Liver; Methionine; Nucleosides; Swine; Tritium | 1967 |
Patterns of methionine and lysine biosynthesis in the Trypanosomatidae during growth.
Topics: Adipates; Eukaryota; Folic Acid; Lysine; Methionine; Pimelic Acids; Trypanosoma | 1967 |
Effect of vitamin B-12 in choline deficiency in the rat.
Topics: Amino Acids; Animals; Body Weight; Choline; Choline Deficiency; Diet; FIGLU Test; Folic Acid; Growth; Hematocrit; Hemoglobins; Kidney; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Rats; Vitamin B 12; Vitamin B Deficiency | 1967 |
Trans-sulfuration in mammals. The methionine-sparing effect of cystine.
Topics: Cystine; Folic Acid; Homocystinuria; Humans; Hydro-Lyases; Liver; Methionine; Transferases | 1967 |
Vitamin B12 regulates folate metabolism by the supply of formate.
Topics: Animals; Folic Acid; Formates; Methionine; Models, Biological; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Tetrahydrofolates; Vitamin B 12 | 1980 |
The methyl folate trap. A physiological response in man to prevent methyl group deficiency in kwashiorkor (methionine deficiency) and an explanation for folic-acid induced exacerbation of subacute combined degeneration in pernicious anaemia.
Topics: Acute Disease; Anemia, Pernicious; Bone Marrow; Cell Division; Folic Acid; Folic Acid Deficiency; Humans; Kwashiorkor; Methionine; Methotrexate; Models, Biological; Vitamin B 12 Deficiency | 1981 |
The methyl-folate trap and the supply of S-adenosylomethionine.
Topics: Brain; Brain Diseases; Folic Acid; Methionine; Methylation; S-Adenosylmethionine; Vitamin B 12 Deficiency | 1981 |
Methotrexate hepatotoxicity.
Topics: Animals; Betaine; Cholesterol Esters; Folic Acid; Homocysteine; Lipotropic Agents; Liver; Male; Methionine; Methotrexate; Methylation; Rats; Tetrahydrofolates; Triglycerides | 1984 |
Folate. Its metabolism and utilization.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport, Active; Cell Division; Cell Line; Cell Membrane; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Mucosa; Lacticaseibacillus casei; Methionine; Mice; Molecular Conformation; Oxidation-Reduction; Pregnancy; Pteroylpolyglutamic Acids; Rats | 1984 |
Polyglutamylfolate synthesis in Neurospora crassa: changes in pool size following growth in glycine- and methionine-supplemented media.
Topics: Culture Media; Folic Acid; Glycine; GTP Cyclohydrolase; Methionine; Neurospora; Neurospora crassa; Pteroylpolyglutamic Acids | 1980 |
Folic acid and chromosome breakage. II. A methionine effect similar to that in fragile X expression.
Topics: Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Culture Media; Folic Acid; Fragile X Syndrome; Humans; Metaphase; Methionine | 1984 |
The role of methionine in the intracellular accumulation and function of folates.
Topics: Animals; Cercopithecus; DNA Replication; Folic Acid; Macaca fascicularis; Methionine; Mice; Mice, Inbred Strains; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains; Species Specificity; Thymidine; Tritium | 1983 |
Tissue S-adenosylmethionine levels in fruit bats (Rousettus aegyptiacus) with nitrous oxide-induced neuropathy.
Topics: Animals; Brain; Cerebellar Ataxia; Chiroptera; Diet; Folic Acid; Liver; Methionine; Nitrous Oxide; Paralysis; S-Adenosylmethionine; Vitamin B 12 | 1983 |
The transmethylation and one-carbon cycle hypotheses of schizophrenia.
Topics: Brain; Catecholamines; Folic Acid; Humans; Kinetics; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia | 1983 |
[Effect of folic acid on 35S-methionine transport in vitro].
Topics: Animals; Biological Transport; Chickens; Folic Acid; In Vitro Techniques; Intestinal Absorption; Jejunum; Male; Methionine; Sulfur Radioisotopes | 1983 |
Folate, methionine, and the fragile X chromosome.
Topics: Cells, Cultured; Chromosome Fragility; Folic Acid; Humans; Methionine | 1984 |
[Evaluation of biochemical criteria for sensitivity of tumor cells to methotrexate by means of mathematic simulation].
Topics: Animals; Carcinoma, Ehrlich Tumor; Folic Acid; Kinetics; Leukemia L1210; Mathematics; Methionine; Methotrexate; Models, Biological; Purines; Serine; Tetrahydrofolate Dehydrogenase; Thymidine Monophosphate | 1980 |
[Mathematical description and study of the folic acid cycle reactions].
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Folic Acid; Humans; Kinetics; Leukemia L1210; Mathematics; Methionine; Methotrexate; Mice; Purines; Rats; Serine; Tetrahydrofolate Dehydrogenase; Thymidine Monophosphate | 1980 |
The role of methionine in regulating folate-dependent reactions in isolated rat hepatocytes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carbon Dioxide; Enzyme Activation; Folic Acid; Formates; Histidine; In Vitro Techniques; Liver; Male; Methionine; Oxidation-Reduction; Rats | 1981 |
Inhibition of serine metabolism by tetrahydrohomofolate in L1210 mouse leukemia cells.
Topics: Animals; Cell Division; Cells, Cultured; Folic Acid; Glycine Hydroxymethyltransferase; Leukemia L1210; Methionine; Mice; Serine | 1981 |
Studies on the haemopoietic toxicity of nitrous oxide in man.
Topics: Anesthesia, General; Bone Marrow; Deoxyuridine; Folic Acid; Hematopoiesis; Humans; Megaloblasts; Methionine; Neutrophils; Nitrous Oxide; Platelet Count; Time Factors; Vitamin B 12 | 1983 |
Chronic cobalamin inactivation impairs folate polyglutamate synthesis in the rat.
Topics: Adenosine; Animals; Deoxyadenosines; Folic Acid; Formyltetrahydrofolates; Liver; Male; Methionine; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tetrahydrofolates; Thionucleosides; Vitamin B 12; Vitamin B 12 Deficiency | 1983 |
Kearns-Sayre syndrome with reduced plasma and cerebrospinal fluid folate.
Topics: Adolescent; Adult; Carnitine; Child; Female; Folic Acid; Folic Acid Deficiency; Humans; Kearns-Sayre Syndrome; Methionine; Mitochondria, Muscle; Muscles; Ophthalmoplegia; Time Factors | 1983 |
Methionine synthesis, aminoimidazole carboxamide excretion and folate levels in pregnant rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aminoimidazole Carboxamide; Animals; Body Weight; Diet; Female; Folic Acid; Glutamate Formimidoyltransferase; Glycine Hydroxymethyltransferase; Homocystine; Hydroxymethyl and Formyl Transferases; Imidazoles; Liver; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Pregnancy; Pregnancy, Animal; Rats; Tetrahydrofolates; Transferases | 1980 |
Nutritional interactions of vitamin B12, folic acid, and thyroxine.
Topics: Animals; Folic Acid; Histidine; Hyperthyroidism; Liver; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Nutritional Physiological Phenomena; Thiouracil; Thyroid Gland; Thyroidectomy; Thyroxine; Tissue Extracts; Vitamin B 12 | 1980 |
Vitamin B12-dependent replication of L1210 mouse leukemia cells. A model system for cobalamin-folate inter-relationships.
Topics: Animals; Cell Division; Folic Acid; Kinetics; Leucovorin; Leukemia L1210; Methionine; Mice; Structure-Activity Relationship; Vitamin B 12 | 1981 |
Folate-responsive homocystinuria and "schizophrenia'.
Topics: Adolescent; Female; Folic Acid; Homocystinuria; Humans; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Models, Biological; Oxidoreductases; Schizophrenia | 1982 |
Homocystinuria caused by 5,10-methylenetetrahydrofolate reductase deficiency: a case in an infant responding to methionine, folinic acid, pyridoxine, and vitamin B12 therapy.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alcohol Oxidoreductases; Amino Acids; Drug Therapy, Combination; Female; Folic Acid; Homocystinuria; Humans; Infant; Leucovorin; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Pyridoxine; Skin; Tetrahydrofolates; Vitamin B 12 | 1981 |
Folate pentaglutamate and folate hexaglutamate mediated one-carbon metabolism.
Topics: Animals; Carbon; Folic Acid; Histidine; Liver; Male; Methionine; Nitrous Oxide; Pteroylpolyglutamic Acids; Rats; Structure-Activity Relationship | 1982 |
[Studies in mice on diminishing acute toxicity of violamycin BI by combined therapy (author's transl)].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Ascorbic Acid; Carnitine; Cysteine; Dogs; Drug Interactions; Female; Folic Acid; Male; Methionine; Mice; Rabbits; Rats; Rats, Inbred Strains; Swine; Vitamin E | 1982 |
The regulation of one-carbon oxidation in the rat by nitrous oxide and methionine.
Topics: Animals; Carbon Radioisotopes; Folic Acid; Formates; Kinetics; Liver; Male; Methionine; Nitrous Oxide; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1982 |
Cobalamin inactivation by nitrous oxide produces severe neurological impairment in fruit bats : protection by methionine and aggravation by folates.
Topics: Animals; Chiroptera; Diet; Folic Acid; Formyltetrahydrofolates; Methionine; Nervous System Diseases; Nitrous Oxide; Vitamin B 12 Deficiency | 1982 |
How vitamin B12 acts.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Animals; Folic Acid; Humans; Methionine; Pteroylpolyglutamic Acids; S-Adenosylmethionine; Thymidine; Vitamin B 12 Deficiency | 1981 |
Utilization of administered folacin derivatives by rats fed a diet low in methionine and folacin.
Topics: Animals; Diet; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Male; Methionine; Rats | 1980 |
The use of betaine for the treatment of homocystinuria.
Topics: Administration, Oral; Adult; Betaine; Child; Female; Folic Acid; Homocystine; Homocystinuria; Humans; Male; Methionine; Pyridoxine | 1981 |
Effects of diets with or without folic acid, with or without methionine, on fetus development, folate stores and folic acid-dependent enzyme activities in the rat.
Topics: Animals; Female; Fetus; Folic Acid; Folic Acid Deficiency; Glutamate Formimidoyltransferase; Glycine Hydroxymethyltransferase; Hydroxymethyl and Formyl Transferases; Liver; Methionine; Pregnancy; Pregnancy Complications; Rats; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Transferases | 1981 |
The role of methionine and vitamin B12 in folate incorporation by rat liver.
Topics: Animals; Folic Acid; Liver; Methionine; Nitrous Oxide; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1980 |
Metabolic responses of folic acid and related compounds to thyroxine in rats.
Topics: Animals; Folic Acid; Formiminoglutamic Acid; Histidine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Tetrahydrofolates; Thyroidectomy; Thyroxine | 1980 |
Effect of methionine on the metabolic fate of liver folates in vitamin B12-deficient rats.
Topics: Animals; Cells, Cultured; Ethanolamines; Folic Acid; Liver; Male; Methionine; Methylation; Phospholipids; Rats; Stimulation, Chemical; Tetrahydrofolates; Vitamin B 12 Deficiency | 1980 |
Methionine recycling in brain: a role for folates and vitamin B-12.
Topics: Animals; Brain; Dopamine; Fasting; Folic Acid; In Vitro Techniques; Liver; Methionine; Methyltransferases; Rabbits; Rats; Vitamin B 12 | 1980 |
The folic acid requirements of starting broiler chicks fed diets based on practical ingredients. 2. Interrelationships with dietary methionine.
Topics: Animals; Chickens; Folic Acid; Food, Fortified; Male; Methionine; Nutritional Requirements | 1995 |
Carbon tetrachloride-induced hepatic injury is associated with global DNA hypomethylation and homocysteinemia: effect of S-adenosylmethionine treatment.
Topics: Animals; Carbon Tetrachloride; Cystathionine; DNA; Folic Acid; Homocysteine; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Effective homocysteine metabolism may protect South African blacks against coronary heart disease.
Topics: Adult; Black People; Coronary Disease; Folic Acid; Homocysteine; Humans; Male; Methionine; South Africa; Vitamin B 12; Vitamins; White People | 1995 |
Isolated persistent hypermethioninemia.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; Folic Acid; Humans; Infant; Male; Methionine; Prognosis; Tyrosine | 1995 |
Alcohol, low-methionine--low-folate diets, and risk of colon cancer in men.
Topics: Adenoma; Adult; Aged; Alcohol Drinking; Carcinoma; Colonic Neoplasms; Diet; Folic Acid; Humans; Male; Methionine; Middle Aged; Risk Factors; Surveys and Questionnaires | 1995 |
Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats.
Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Genes, myc; Liver; Male; Methionine; Methylation; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1995 |
Folylpolyglutamate synthesis in Neurospora crassa: transformation of polyglutamate-deficient mutants.
Topics: 4-Aminobenzoic Acid; Folic Acid; Genes, Fungal; Methionine; Neurospora crassa; Peptide Synthases | 1995 |
Formyltetrahydrofolate hydrolase, a regulatory enzyme that functions to balance pools of tetrahydrofolate and one-carbon tetrahydrofolate adducts in Escherichia coli.
Topics: Allosteric Regulation; Amidohydrolases; Base Sequence; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Folic Acid; Formyltetrahydrofolates; Glycine; Methionine; Models, Biological; Molecular Sequence Data; Protein Conformation; Purine Nucleotides; Recombinant Proteins; Tetrahydrofolates | 1995 |
Involvement of folic acid and methionine in the synthesis of certain membrane-associated nucleotide sugars by Enterococcus hirae.
Topics: Cell Fractionation; Cell Membrane; Cell-Free System; Enterococcus; Folic Acid; Methionine; Monosaccharides; S-Adenosylmethionine; Serine; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars | 1994 |
Plasma concentrations of homocysteine and other aminothiol compounds are related to food intake in healthy human subjects.
Topics: Adult; Circadian Rhythm; Cysteine; Dietary Proteins; Dipeptides; Fasting; Female; Folic Acid; Food; Homocysteine; Humans; Kinetics; Male; Methionine | 1994 |
Modulation of expression of fos and Ha-ras oncogenes and ornithine decarboxylase activity in mammary gland and liver of young female rats by the absence of dietary lipotropes.
Topics: Animals; Choline; Choline Deficiency; Diet; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Genes, fos; Genes, ras; Liver; Mammary Glands, Animal; Methionine; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Vitamin B 12 Deficiency | 1994 |
Maternal hyperhomocysteinemia: a risk factor for neural-tube defects?
Topics: Adult; Anencephaly; Cystathionine beta-Synthase; Encephalocele; Female; Folic Acid; Homocysteine; Humans; Meningomyelocele; Methionine; Neural Tube Defects; Pregnancy; Pregnancy Complications; Risk Factors | 1994 |
Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction.
Topics: Adult; Choline; Diet; Folic Acid; Folic Acid Deficiency; Glycine max; Homocysteine; Humans; Male; Methionine; Middle Aged; Nutritional Requirements; Nutritional Status; Vitamin B 12 | 1994 |
Development and reversion of methionine dependence in a human glioma cell line: relation to homocysteine remethylation and cobalamin status.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Brain Neoplasms; Female; Folic Acid; Glioblastoma; Homocysteine; Humans; Methionine; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12 | 1994 |
Changes in translational accuracy of Escherichia coli when folate metabolism is perturbed.
Topics: Aminopterin; Coliphages; Escherichia coli; Folic Acid; Folic Acid Antagonists; Genes, Bacterial; Methionine; Models, Genetic; Mutation; Peptide Synthases; Protein Biosynthesis; RNA, Transfer, Trp; Suppression, Genetic; Tetrahydrofolates; Thymidylate Synthase | 1994 |
Study on the presence of homocysteine in ovarian follicular fluid.
Topics: Adult; Female; Folic Acid; Follicular Fluid; Homocysteine; Humans; Methionine; Pyridoxine; Reference Values; Vitamin B 12 | 1993 |
Methionine synthase inactivation by nitrous oxide during methionine loading of normal human fibroblasts. Homocysteine remethylation as determinant of enzyme inactivation and homocysteine export.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Division; Cell Line; Enzyme Activation; Extracellular Space; Fetus; Fibroblasts; Folic Acid; Homocysteine; Humans; Infant; Lung; Male; Methionine; Methylation; Nitrous Oxide; S-Adenosylmethionine | 1993 |
Hyperhomocysteinemia in patients operated for lower extremity ischaemia below the age of 50--effect of smoking and extent of disease.
Topics: Adult; Arteriosclerosis; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Ischemia; Male; Methionine; Middle Aged; Postoperative Complications; Pyridoxine; Risk Factors; Smoking; Vitamin B 12 | 1993 |
Regulation of folate and one-carbon metabolism in mammalian cells. II. Effect of folylpoly-gamma-glutamate synthetase substrate specificity and level on folate metabolism and folylpoly-gamma-glutamate specificity of metabolic cycles of one-carbon metaboli
Topics: Animals; Base Sequence; Carbon; Cells, Cultured; CHO Cells; Cricetinae; Escherichia coli; Folic Acid; gamma-Glutamyl Hydrolase; Glutamates; Humans; Methionine; Molecular Sequence Data; Oligodeoxyribonucleotides; Peptide Synthases; Substrate Specificity | 1993 |
Methionine but not folinic acid or vitamin B-12 alters the frequency of neural tube defects in Axd mutant mice.
Topics: Amino Acids; Animals; Embryo, Mammalian; Female; Folic Acid; Injections, Intraperitoneal; Male; Methionine; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Mutant Strains; Neural Tube Defects; Vitamin B 12 | 1993 |
Symptomatic and asymptomatic methylenetetrahydrofolate reductase deficiency in two adult brothers.
Topics: Adult; Betaine; Enzyme Stability; Folic Acid; Homocystine; Humans; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nervous System Diseases; Oxidoreductases Acting on CH-NH Group Donors; Paraparesis, Tropical Spastic | 1993 |
Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.
Topics: Amino Acid Sequence; Animals; Choline; DNA; Folic Acid; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Liver Neoplasms; Male; Methionine; Methylation; Methyltransferases; Molecular Sequence Data; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; Vitamin B 12 | 1993 |
Folate, methionine, and alcohol intake and risk of colorectal adenoma.
Topics: Adenoma; Adult; Aged; Alcohol Drinking; Colorectal Neoplasms; Feeding Behavior; Female; Folic Acid; Humans; Male; Methionine; Methylation; Middle Aged; Prevalence; Prospective Studies; Proto-Oncogene Mas; Risk; Surveys and Questionnaires | 1993 |
Plasma homocysteine and severity of atherosclerosis in young patients with lower-limb atherosclerotic disease.
Topics: Adult; Arteriosclerosis; Cerebrovascular Disorders; Coronary Disease; Fasting; Female; Folic Acid; Homocysteine; Humans; Leg; Male; Methionine; Middle Aged; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
Kinetics of total plasma homocysteine in subjects with hyperhomocysteinemia due to folate or cobalamin deficiency.
Topics: Adolescent; Adult; Aged; Female; Folic Acid; Folic Acid Deficiency; Half-Life; Hematinics; Homocysteine; Humans; Kinetics; Male; Methionine; Methylmalonic Acid; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Elevated plasma concentration of reduced homocysteine in patients with human immunodeficiency virus infection.
Topics: Adult; CD4 Lymphocyte Count; Cysteine; Dipeptides; Female; Folic Acid; HIV Antibodies; HIV Infections; HIV-1; Homocysteine; Humans; Interleukin-2; Lymphocytes; Male; Methionine; Middle Aged; Oxidation-Reduction; Oxidative Stress; Vitamin B 12 | 1996 |
Reproducibility of recall of adolescent diet: Nurses' Health Study (United States).
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Adult; Aged; Alcohol Drinking; Ascorbic Acid; Cholesterol, Dietary; Cohort Studies; Diet; Dietary Proteins; Energy Intake; Female; Folic Acid; Food; Humans; Mental Recall; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Reproducibility of Results; Surveys and Questionnaires; Vitamin E | 1995 |
Carbon flow through the hepatic folate-dependent one-carbon pool is not altered in vitamin A-deficient rats.
Topics: Animals; Carbon; Carbon Radioisotopes; Diterpenes; Folic Acid; Liver; Male; Methionine; Random Allocation; Rats; Rats, Sprague-Dawley; Retinyl Esters; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tritium; Vitamin A; Vitamin A Deficiency | 1996 |
Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate.
Topics: Case-Control Studies; Diet; Diet Surveys; Fasting; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methionine; Methylation; Middle Aged; Myocardial Infarction; Odds Ratio; Pyridoxine; Risk Factors; Vitamin B 12 | 1996 |
Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Apoptosis; Cell Division; Deoxyuracil Nucleotides; Ethanol; Folic Acid; Homocysteine; Liver; Male; Methionine; Proliferating Cell Nuclear Antigen; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Thymine Nucleotides | 1996 |
Lipotrope-mediated c-jun and ornithine decarboxylase mRNA expression in mammary acinar cells.
Topics: Animals; Choline; Female; Folic Acid; Gene Expression; Genes, jun; Mammary Glands, Animal; Methionine; Ornithine Decarboxylase; Rats; RNA, Messenger; Vitamin B 12 | 1996 |
A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer.
Topics: Adult; Aged; Colorectal Neoplasms; Ethanol; Folic Acid; Genotype; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Risk Factors | 1996 |
[The prevalence of hyperhomocysteinemia in thromboangiitis obliterans. Does homocysteine play a role pathogenetically?].
Topics: Adult; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Prevalence; Pyridoxine; Risk Factors; Smoking; Statistics, Nonparametric; Thromboangiitis Obliterans; Time Factors; Vitamin B 12 | 1996 |
The influence of dietary folate and methionine on the metabolic disposition of endotoxic homocysteine.
Topics: Adolescent; Adult; Aged; Diet; Endotoxins; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Reference Values | 1996 |
Effect of folate deficiency and folate and B12 excess on memory functioning in young chicks.
Topics: Animals; Avoidance Learning; Chickens; Dose-Response Relationship, Drug; Drug Synergism; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Memory; Methionine; Methotrexate; Reflex; Time Factors; Vitamin B 12 | 1997 |
Fasting and post-methionine homocyst(e)ine levels in a healthy Australian population.
Topics: Adult; Aged; Australia; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Reference Values; Vitamin B 12 | 1997 |
Cyanocobalamin [c-lactam] inhibits vitamin B12 and causes cytotoxicity in HL60 cells: methionine protects cells completely.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Death; Enzyme Inhibitors; Folic Acid; HL-60 Cells; Homocysteine; Humans; Hydroxocobalamin; Methionine; Methylmalonyl-CoA Mutase; Propionates; Tetrahydrofolates; Vitamin B 12 | 1997 |
Are dietary factors involved in DNA methylation associated with colon cancer?
Topics: Aged; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Colonic Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Pyridoxine; Retrospective Studies; Risk Factors; Vitamin B 12 | 1997 |
The 677C-->T mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease.
Topics: Adult; Aged; Alcohol Drinking; Case-Control Studies; Comorbidity; Coronary Artery Disease; Disease Susceptibility; Erythrocytes; Fasting; Female; Folic Acid; Genes; Genotype; Homocysteine; Humans; Hyperlipidemias; Hypertension; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Obesity; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Smoking | 1997 |
Kinetic basis of hyperhomocysteinemia in patients with chronic renal failure.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Kinetics; Male; Methionine; Middle Aged | 1997 |
Protein expression in response to folate stress in Escherichia coli.
Topics: Bacterial Proteins; Electrophoresis, Gel, Two-Dimensional; Escherichia coli; Folic Acid; Folic Acid Antagonists; Glycine; Heat-Shock Proteins; Inosine; Isoelectric Point; Methionine; Thymine; Trimethoprim | 1997 |
Homocysteine accumulation in human ovarian carcinoma ascitic/cystic fluids possibly caused by metabolic alteration of the methionine cycle in ovarian carcinoma cells.
Topics: Adult; Aged; Ascitic Fluid; Cysteine; Female; Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Middle Aged; Ovarian Neoplasms; Vitamin B 12 | 1997 |
Excess prevalence of fasting and postmethionine-loading hyperhomocysteinemia in stable renal transplant recipients.
Topics: Adult; Aged; Arteriosclerosis; Fasting; Female; Folic Acid; Homocysteine; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Methionine; Middle Aged; Pyridoxine | 1997 |
Low concentrations of folate in serum and erythrocytes of smokers: methionine loading decreases folate concentrations in serum of smokers and nonsmokers.
Topics: Adult; Cysteine; Dipeptides; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Smoking | 1997 |
Is dietary intake of methionine associated with a reduction in risk for neural tube defect-affected pregnancies?
Topics: Adult; Case-Control Studies; Confidence Intervals; Dietary Supplements; Female; Folic Acid; Humans; Maternal-Fetal Exchange; Methionine; Neural Tube Defects; Odds Ratio; Pregnancy; Risk Factors | 1997 |
Identification of new regulatory genes controlling synthesis of folate-dependent enzymes in Aspergillus nidulans.
Topics: Aspergillus nidulans; Folic Acid; Genes, Fungal; Genes, Regulator; Genetic Linkage; Methionine; Mutation; Peptide Synthases; Suppression, Genetic | 1997 |
[Influence of levels of vitamin B2, B12, and folic acid on the values of basal homocysteinemia and after methionine overload].
Topics: Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Pyridoxine; Vitamin B 12 | 1998 |
Embryonic folate metabolism and mouse neural tube defects.
Topics: Animals; Central Nervous System; Deoxyuracil Nucleotides; DNA-Binding Proteins; Embryo, Mammalian; Female; Folic Acid; Humans; Male; Methionine; Mice; Mice, Inbred CBA; Mutation; Neural Tube Defects; Paired Box Transcription Factors; PAX3 Transcription Factor; Pyrimidines; Tetrahydrofolates; Thymidine; Thymidine Monophosphate; Transcription Factors | 1998 |
Neural-tube defects are associated with low concentrations of cobalamin (vitamin B12) in amniotic fluid.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amniocentesis; Amniotic Fluid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Neural Tube Defects; Pilot Projects; Pregnancy; Reference Values; Vitamin B 12 | 1998 |
Plasma folic acid cutoff value, derived from its relationship with homocyst(e)ine.
Topics: Adult; Aged; Aged, 80 and over; Fasting; Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Pyridoxine; Reference Values | 1998 |
VPA-induced neural tube defects in mice. I. Altered metabolism of sulfur amino acids and glutathione.
Topics: Abnormalities, Drug-Induced; Amino Acids; Animals; Anticonvulsants; Female; Folic Acid; Glutathione; Homocysteine; Liver; Methionine; Mice; Neural Tube Defects; Pregnancy; Valproic Acid | 1998 |
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc | 1998 |
A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: results among U.S. men.
Topics: Adult; Aged; Alleles; Case-Control Studies; Confidence Intervals; Coronary Disease; Diet; Folic Acid; Follow-Up Studies; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Riboflavin; Risk Factors; Smoking; United States; Vitamin B 12 | 1998 |
Ability of endogenous folate from soy protein isolate to maintain plasma homocysteine and hepatic DNA methylation during methyl group depletion in rats.
Topics: 5-Methylcytosine; Animals; Caseins; Choline Deficiency; Cytosine; Dietary Proteins; DNA; DNA Methylation; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; Soybean Proteins; Weaning | 1998 |
Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study.
Topics: Adult; Colonic Neoplasms; Confounding Factors, Epidemiologic; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Incidence; Methionine; Middle Aged; Multivariate Analysis; Prospective Studies; Risk Factors; Surveys and Questionnaires; Time Factors; Vitamins | 1998 |
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adult; Colorectal Neoplasms; Ethanol; Female; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Risk Factors | 1998 |
Folate status, homocysteine metabolism, and methylene tetrahydrofolate reductase genotype in rural South African blacks with a history of pregnancy complicated by neural tube defects.
Topics: Adult; Black People; DNA; Female; Folic Acid; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Neural Tube Defects; Nutritional Status; Pregnancy; Pregnancy Complications; Rural Population; South Africa | 1999 |
Endothelial dysfunction by acute hyperhomocyst(e)inaemia: restoration by folic acid.
Topics: Acute Disease; Adult; Brachial Artery; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methionine; Vasodilation | 1999 |
Impaired methionine synthesis and hypomethylation in rats exposed to valproate during gestation.
Topics: Analysis of Variance; Animals; Female; Folic Acid; Gestational Age; Homocysteine; Methionine; Methylation; Rats; Rats, Wistar; Valproic Acid | 1999 |
The effect of folic acid addition on insulin level and some carbohydrate metabolism indices in male rats fed with excess of methionine.
Topics: Animals; Blood Glucose; Body Weight; Diet; Dietary Carbohydrates; Dose-Response Relationship, Drug; Eating; Folic Acid; Glycogen; Insulin; Liver; Male; Methionine; Muscle, Skeletal; Rats; Rats, Wistar | 1993 |
Combination of low-dose folic acid and pyridoxine for treatment of hyperhomocysteinaemia in patients with premature arterial disease and their relatives.
Topics: Adult; Age of Onset; Arteriosclerosis; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Prospective Studies; Pyridoxine; Risk Factors | 1999 |
Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.
Topics: Adult; Age Factors; Amino Acid Substitution; Arteriosclerosis; Body Mass Index; Comorbidity; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipids; Male; Menopause; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pyridoxine; Smoking; Vitamin B 12 | 1999 |
Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease.
Topics: Administration, Oral; Adult; Aged; Albuminuria; Analysis of Variance; Blood Pressure; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Postmenopause; Premenopause; Pyridoxal Phosphate; Regression Analysis; Risk Factors; Vitamin B 12 | 1999 |
[Obstetric problems followed by stroke].
Topics: Abortion, Habitual; Adult; Arteriosclerosis; Cerebral Infarction; Diagnosis, Differential; Female; Fetal Death; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Male; Methionine; Nutrition Disorders; Placental Insufficiency; Pregnancy; Pregnancy Complications, Cardiovascular; Pyridoxine; Smoking; Venous Thrombosis; Vitamin B 6 Deficiency | 1999 |
Methylenetetrahydrofolate reductase, diet, and risk of colon cancer.
Topics: Adult; Aged; Alcohol Drinking; California; Case-Control Studies; Colonic Neoplasms; Diet; Diet Surveys; DNA Methylation; Female; Folic Acid; Genotype; Homozygote; Humans; Incidence; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Vitamin B 12 | 1999 |
Molecular basis for methionine synthase reductase deficiency in patients belonging to the cblE complementation group of disorders in folate/cobalamin metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; DNA Mutational Analysis; DNA, Complementary; Enzyme Activation; Ferredoxin-NADP Reductase; Folic Acid; Genes, Recessive; Genetic Complementation Test; Heteroduplex Analysis; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Mutation; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; Sequence Analysis, DNA; Vitamin B 12 | 1999 |
Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome.
Topics: Adult; Alcohol Drinking; Case-Control Studies; Chromatography, High Pressure Liquid; Deoxyribonucleases, Type II Site-Specific; Diet Surveys; Diet, Reducing; Dietary Supplements; DNA; Down Syndrome; Electrophoresis, Agar Gel; Female; Folic Acid; Genotype; Homocysteine; Humans; Methionine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Risk Factors; Surveys and Questionnaires | 1999 |
Nonsyndromic orofacial clefts: association with maternal hyperhomocysteinemia.
Topics: Adult; Case-Control Studies; Child, Preschool; Cleft Lip; Cleft Palate; Erythrocytes; Fasting; Female; Folic Acid; Homocysteine; Humans; Infant; Maternal-Fetal Exchange; Methionine; Pregnancy; Pyridoxine; Risk Factors; Vitamin B 12 | 1999 |
The effect of diet on plasma homocysteine concentrations in healthy male subjects.
Topics: Adult; Cross-Sectional Studies; Diet; Diet, Vegetarian; Fasting; Folic Acid; Homocysteine; Humans; Male; Meat; Methionine; Methylation; Middle Aged; Vitamin B 12 | 1999 |
[Gender differences in serum homocysteine levels and associated factors].
Topics: Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sex Characteristics; Vitamin B 12 | 1999 |
Amniotic fluid B12, calcium, and lead levels associated with neural tube defects.
Topics: Adult; Amniocentesis; Amniotic Fluid; Calcium; Cross-Sectional Studies; Female; Folic Acid; Gestational Age; Hispanic or Latino; Humans; Lead; Maternal Age; Methionine; Neural Tube Defects; Pregnancy; Retrospective Studies; Ultrasonography, Prenatal; Vitamin B 12 | 1999 |
Effect of short-term vitamin (folic acid, vitamins B6 and B12) administration on endothelial dysfunction induced by post-methionine load hyperhomocysteinemia.
Topics: Administration, Oral; Adult; Blood Flow Velocity; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Treatment Outcome; Vasodilation; Vitamin B 12 | 1999 |
The effect of estrogen replacement therapy on total plasma homocysteine in healthy postmenopausal women.
Topics: Adult; Estrogen Replacement Therapy; Folic Acid; Homocysteine; Humans; Linear Models; Lipids; Methionine; Middle Aged; Postmenopause; Pyridoxine; Reference Values; Time Factors; Vitamin B 12 | 2000 |
Dietary folate consumption and breast cancer risk.
Topics: Aged; Alcohol Drinking; Anticarcinogenic Agents; Breast Neoplasms; Carcinoma; Diet; Female; Folic Acid; Humans; Incidence; Life Style; Menopause; Methionine; Middle Aged; Odds Ratio; Poisson Distribution; Risk; Risk Factors | 2000 |
Normohomocysteinaemia and vitamin-treated hyperhomocysteinaemia are associated with similar risks of cardiovascular events in patients with premature atherothrombotic cerebrovascular disease. A prospective cohort study.
Topics: Adult; Arteriosclerosis; Female; Folic Acid; Follow-Up Studies; Hematinics; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Mass Screening; Methionine; Middle Aged; Proportional Hazards Models; Prospective Studies; Pyridoxine; Risk Assessment; Risk Factors; Stroke; Treatment Outcome | 2000 |
High-dose folic acid supplementation in rats: effects on gestation and the methionine cycle.
Topics: Animals; Dietary Supplements; Female; Fetal Weight; Folic Acid; Methionine; Methylation; Nutritional Status; Pregnancy; Pregnancy Outcome; Rats; Rats, Wistar; S-Adenosylmethionine | 2000 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Effects of supplemental methionine on antiserum-induced dysmorphology in rat embryos cultured in vitro.
Topics: Animals; Congenital Abnormalities; Culture Techniques; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Folic Acid; Immune Sera; Lethal Dose 50; Leucine; Maternal Exposure; Methionine; Rats; Rats, Wistar; Yolk Sac | 2000 |
Polyglutamylation of folate coenzymes is necessary for methionine biosynthesis and maintenance of intact mitochondrial genome in Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Cloning, Molecular; DNA, Mitochondrial; Folic Acid; Genome, Fungal; Methionine; Molecular Sequence Data; Peptide Synthases; Polyglutamic Acid; Saccharomyces cerevisiae; Sequence Homology, Amino Acid | 2000 |
Homocysteine thiolactone and protein homocysteinylation in human endothelial cells: implications for atherosclerosis.
Topics: Arteriosclerosis; Cells, Cultured; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Infant, Newborn; Lipoproteins, HDL; Methionine; Proteins | 2000 |
Impaired glucose tolerance (IGT) is not associated with disturbed homocysteine metabolism.
Topics: Blood Glucose; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fasting; Folic Acid; Homocysteine; Humans; Insulin; Male; Methionine; Middle Aged; Proinsulin; Risk Factors; Time Factors; Vitamin B 12 | 2000 |
DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats.
Topics: Animals; Choline Deficiency; Colon; Colonic Neoplasms; Comet Assay; DNA; DNA Damage; DNA Methylation; Folic Acid; Folic Acid Deficiency; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Intake of fruits, vegetables, folic acid and related nutrients and risk of breast cancer in postmenopausal women.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Breast Neoplasms; Case-Control Studies; Cysteine; Diet; Europe; Female; Folic Acid; Fruit; Humans; Methionine; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires; Vegetables; Women's Health | 1998 |
Methylenetetrahydrofolate reductase deficiency: importance of early diagnosis.
Topics: Betaine; Child, Preschool; Diagnosis, Differential; Fatal Outcome; Fibroblasts; Folic Acid; Hematinics; Homocysteine; Homocystinuria; Homozygote; Humans; Infant; Intellectual Disability; Lipotropic Agents; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Treatment Outcome | 2000 |
The (non-)sense of the methionine loading test for detecting hyperhomocysteinaemia.
Topics: Cardiovascular Diseases; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Methionine | 2000 |
[Homocysteine and its metabolites in chronic renal insufficiency and the effect of a vitamin replacement].
Topics: Adult; Aged; Arteriosclerosis; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Middle Aged; Pyridoxine; Renal Dialysis; Severity of Illness Index; Vitamin B 12; Vitamin B Complex | 2000 |
Effect of consecutive lower-dose cisplatin in enhancement of 5-fluorouracil cytotoxicity in experimental tumor cells in vivo.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Synergism; Enzyme Induction; Fluorouracil; Folic Acid; Male; Methionine; Mice; Neoplasm Transplantation; Oxonic Acid; Pyridines; Rats; Sarcoma, Yoshida; Tegafur | 2000 |
Homocysteine levels in vegetarians versus omnivores.
Topics: Adult; Aged; Diet; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Slovakia; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Increased uracil misincorporation in lymphocytes from folate-deficient rats.
Topics: Animals; Choline Deficiency; Comet Assay; DNA; DNA Damage; Erythrocytes; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; Rats; Uracil; Vitamin B 12 | 2000 |
Defining the steps of the folate one-carbon shuffle and homocysteine metabolism.
Topics: Folic Acid; Glycine; Homocysteine; Humans; Methionine; Methylation; Serine | 2000 |
Primed, constant infusion with [2H3]serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism.
Topics: Adult; Amino Acids; Cytosol; Folic Acid; Homocysteine; Humans; Infusions, Intravenous; Kinetics; Male; Methionine; Methylation; Mitochondria; Nutritional Status; Pilot Projects; Serine | 2000 |
Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury.
Topics: Administration, Oral; Angioplasty, Balloon; Animals; Carotid Arteries; Carotid Artery Diseases; Cystine; Diet; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Male; Methionine; Rats; Rats, Sprague-Dawley; Tunica Intima; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Targeted disruption of the methionine synthase gene in mice.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Base Sequence; Cardiovascular Diseases; DNA Primers; Embryonic and Fetal Development; Female; Folic Acid; Gene Targeting; Heterozygote; Homocysteine; Homozygote; Humans; Methionine; Mice; Mice, Knockout; Neural Tube Defects; Pregnancy; Risk Factors; Vitamin B 12 Deficiency | 2001 |
Nutritional status of folate and colon cancer risk: evidence from NHANES I epidemiologic follow-up study.
Topics: Adult; Aged; Alcohol Drinking; Colonic Neoplasms; Diet; Female; Folic Acid; Health Surveys; Humans; Male; Methionine; Middle Aged; Nutritional Status; Risk Factors; Smoking; United States | 2001 |
Is there a role of cyclosporine A on total homocysteine export from human renal proximal tubular epithelial cells?
Topics: Biological Transport, Active; Cells, Cultured; Cyclosporine; Epithelial Cells; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubules, Proximal; Methionine; Pyridoxine; Vitamin B 12 | 2001 |
Effects of methionine loading on plasma and erythrocyte sulphur amino acids and sulph-hydryls before and after co-factor supplementation in haemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Sulfur; Case-Control Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Renal Dialysis; Sulfhydryl Compounds | 2001 |
Homocysteine and human reproduction.
Topics: Culture Techniques; Female; Folic Acid; History, 17th Century; History, 20th Century; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Reproduction | 2000 |
Traditional and alternative nutrition--levels of homocysteine and lipid parameters in adults.
Topics: Adult; Aged; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dairy Products; Diet, Vegetarian; Eggs; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Methionine; Middle Aged; Nutritional Physiological Phenomena; Reference Values; Risk Factors; Vitamin B 12 | 2000 |
Mutations in the gene for methylenetetrahydrofolate reductase, homocysteine levels, and vitamin status in women with a history of preeclampsia.
Topics: Birth Weight; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Primers; Electrophoresis, Polyacrylamide Gel; Female; Folic Acid; Genotype; Gestational Age; HELLP Syndrome; Homocysteine; Humans; Infant, Newborn; Linear Models; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Pre-Eclampsia; Pregnancy; Radioimmunoassay; Regression Analysis; Vitamin B 12 | 2001 |
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Cells, Cultured; Diet; Disease Models, Animal; Folic Acid; Humans; Hyperhomocysteinemia; Immunohistochemistry; Male; Matrix Metalloproteinase 9; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridoxine; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thromboplastin; Vascular Cell Adhesion Molecule-1; Vasculitis; Vitamin B 12 | 2001 |
Maternal pyridoxine non-responsive homocystinuria: the role of dietary treatment and anticoagulation.
Topics: Adult; Anticoagulants; Female; Fibrinogen; Folic Acid; Heparin; Homocystinuria; Humans; Methionine; Pregnancy; Pregnancy Complications; Vitamin B 12 | 2001 |
Folate, homocysteine and methionine loading in patients on carbamazepine.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged | 2001 |
Association between polymorphisms of folate- and methionine-metabolizing enzymes and susceptibility to malignant lymphoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Aged, 80 and over; Case-Control Studies; DNA; DNA Methylation; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Logistic Models; Lymphoma; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic | 2001 |
Nitric oxide inhibits methionine synthase activity in vivo and disrupts carbon flow through the folate pathway.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carbon; Cell Line; Coculture Techniques; Cricetinae; Endothelium, Vascular; Folic Acid; Humans; Methionine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Purine Nucleotides; Rats; Serine; Vitamin B 12 | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Mild hyperhomocysteinemia: vitamin supplementation or not?
Topics: Adult; Case-Control Studies; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Mutation; Polymorphism, Genetic; Vascular Diseases; Vitamins | 2001 |
Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism.
Topics: Binding Sites; Catalysis; Diffusion; Escherichia coli; Folic Acid; Hydrogen Bonding; Kinetics; Magnetic Resonance Spectroscopy; Methionine; Models, Chemical; Models, Molecular; Models, Statistical; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Tetrahydrofolate Dehydrogenase | 2001 |
An examination of polymorphic genes and folate metabolism in mothers affected by a spina bifida pregnancy.
Topics: Adult; Alleles; England; Erythrocytes; Female; Folic Acid; Gene Frequency; Humans; Methionine; Methylation; Mutation; Polyglutamic Acid; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Pregnancy; Pteroylpolyglutamic Acids; Spinal Dysraphism; Vitamin B 12 | 2001 |
[Effect of vitamin B6, B12 and folic acid levels on basal blood homocysteine values and after methionine load].
Topics: Folic Acid; Homocysteine; Humans; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2001 |
Determinants of homocysteine during weight reduction in obese children and adolescents.
Topics: Adolescent; Age Factors; Body Composition; Body Mass Index; C-Peptide; Child; Folic Acid; Homocysteine; Humans; Methionine; Obesity; Regression Analysis; Time Factors; Weight Loss | 2001 |
Does a single vitamin B-supplementation induce functional vitamin B-deficiency?
Topics: Adult; Cystathionine; Cysteine; Dietary Supplements; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Models, Biological; Pilot Projects; Time Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2001 |
CblC/D defect combined with haemodynamically highly relevant VSD.
Topics: Female; Folic Acid; Heart Septal Defects, Ventricular; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant, Newborn; Lactic Acid; Metabolism, Inborn Errors; Methionine; Methylmalonic Acid | 2001 |
Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Catalase; Cell Division; DNA Fragmentation; DNA, Neoplasm; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Homocysteine; Humans; Hydrogen Peroxide; Malondialdehyde; Methionine; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Transcription Factors; Tumor Cells, Cultured | 2001 |
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.
Topics: Adenoma; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Choline; Colonic Neoplasms; Diet; Dietary Fats; Epithelium; Female; Folic Acid; Immunoenzyme Techniques; Intestine, Large; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Vitamin B 12 | 2001 |
Low plasma levels of vitamin B(6) are independently associated with a heightened risk of deep-vein thrombosis.
Topics: Adolescent; Adult; Aged; Child; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Risk Factors; Venous Thrombosis; Vitamin B 12; Vitamin B 6 | 2001 |
Plasma folate but not vitamin B(12) or homocysteine concentrations are reduced after short-term vitamin B(6) supplementation.
Topics: Adult; Area Under Curve; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B 6 | 2001 |
Diet-induced mild hyperhomocysteinemia and increased salt intake diminish vascular endothelial function in a synergistic manner.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Carotid Artery, Common; Drug Synergism; Endothelium, Vascular; Folic Acid; Heart Rate; Homocysteine; Hyperhomocysteinemia; Japan; Kidney; Lipid Peroxidation; Lipids; Male; Methionine; Natriuresis; Nitrites; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sodium Chloride, Dietary | 2002 |
High dietary folate supplementation: effects on diet utilization and methionine metabolism in aged rats.
Topics: Aging; Analysis of Variance; Animals; Biomarkers; Dietary Fats; Dietary Proteins; Dietary Supplements; DNA Methylation; Folic Acid; Male; Methionine; Rats; Rats, Wistar | 2002 |
Dietary intake of folic acid and colorectal cancer risk in a cohort of women.
Topics: Body Mass Index; Canada; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Diet; Folic Acid; Humans; Incidence; Methionine; Middle Aged; Risk Factors; Smoking | 2002 |
Effects of hormone replacement therapy and methylenetetrahydrofolate reductase polymorphism on plasma folate and homocysteine levels in postmenopausal Japanese women.
Topics: Adult; Aged; Aged, 80 and over; Apolipoproteins; DNA; Estrogens; Female; Folic Acid; Homocysteine; Hormone Replacement Therapy; Humans; Japan; Lipids; Medroxyprogesterone Acetate; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Polymorphism, Genetic; Progesterone Congeners; Regression Analysis | 2002 |
The influence of folate and multivitamin use on the familial risk of colon cancer in women.
Topics: Adult; Alcoholic Beverages; Cohort Studies; Colonic Neoplasms; Feeding Behavior; Female; Folic Acid; Health Behavior; Humans; Methionine; Middle Aged; Prospective Studies; Risk Assessment; Risk Factors; United States; Vitamins | 2002 |
Classic homocystinuria: clinical, biochemical and radiological observations, and therapeutic outcome of 24 Saudi patients.
Topics: Betaine; Child; Child, Preschool; Combined Modality Therapy; Consanguinity; Drug Monitoring; Drug Therapy, Combination; Female; Folic Acid; Homocystinuria; Humans; Infant; Male; Methionine; Pedigree; Pyridoxine; Saudi Arabia; Treatment Outcome | 1999 |
Cancer and diet. Colon vitamins.
Topics: Alcohol Drinking; Colonic Neoplasms; Diet; DNA Damage; DNA Repair; Female; Folic Acid; Humans; Methionine; United States | 2002 |
Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig.
Topics: Animals; DNA; DNA Methylation; Ethanol; Folic Acid; Folic Acid Deficiency; Homocysteine; Lipid Peroxidation; Liver; Male; Methionine; Oxidation-Reduction; Swine; Swine, Miniature | 2002 |
Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline.
Topics: Animals; Choline; Diet; DNA Methylation; Folic Acid; Methionine; Mice; Rats | 2002 |
Metabolic interactions of alcohol and folate.
Topics: Animals; Ethanol; Folic Acid; Humans; Intestinal Absorption; Liver Diseases, Alcoholic; Methionine | 2002 |
Folate, methionine, alcohol, and colorectal cancer in a prospective study of women in the United States.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Cohort Studies; Colorectal Neoplasms; Feeding Behavior; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Hematinics; Humans; Methionine; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; United States | 2002 |
Folic acid and vitamin B(12) supplementation attenuates isoprenaline-induced myocardial infarction in experimental hyperhomocysteinemic rats.
Topics: Animals; Blood Pressure; Creatine Kinase; Folic Acid; Glutathione; Heart Rate; Hemodynamics; Hyperhomocysteinemia; Isoproterenol; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Methionine; Myocardial Infarction; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Vitamin B 12 | 2002 |
Acute valproate administration impairs methionine metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Anticonvulsants; Betaine-Homocysteine S-Methyltransferase; Female; Folic Acid; Glutathione; Glutathione Disulfide; Homocysteine; Liver; Methionine; Methionine Adenosyltransferase; Methyltransferases; Models, Animal; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Teratogens; Valproic Acid; Vitamin B 6 | 2002 |
Renal tubulointerstitial injury in weanling rats with hyperhomocysteinemia.
Topics: Age Factors; Animal Feed; Animals; Choline; Folic Acid; Homocysteine; Hyperhomocysteinemia; Methionine; Nephritis, Interstitial; Rats; Rats, Inbred F344; Weaning | 2002 |
Dietary folate and colorectal cancer.
Topics: Adult; Alcohol Drinking; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Rectal Neoplasms | 2002 |
A comparison of folic acid and 5-methyltetrahydrofolate for prevention of DNA damage and cell death in human lymphocytes in vitro.
Topics: Adult; Biological Availability; Carrier Proteins; Cell Division; Cells, Cultured; Choline; Chromosome Breakage; Chromosomes, Human; Deoxyuracil Nucleotides; DNA; DNA Damage; DNA Methylation; DNA Replication; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lymphocyte Activation; Lymphocytes; Membrane Transport Proteins; Methionine; Micronucleus Tests; Middle Aged; Oxidation-Reduction; Phytohemagglutinins; Prodrugs; Receptors, Cell Surface; Reduced Folate Carrier Protein; Tetrahydrofolates; Uracil | 2003 |
The effect of folic acid, vitamin B6 and vitamin B12 on the homocysteine levels in rabbits fed by methionine-enriched diets.
Topics: Animals; Diet; Dose-Response Relationship, Drug; Drug Combinations; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rabbits; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2002 |
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
Topics: Anemia; Anemia, Pernicious; Cysteine; Dipeptides; Folic Acid; Glutathione; Homocysteine; Humans; Memory Disorders; Methionine; Movement Disorders; Nervous System Diseases; Retrospective Studies; S-Adenosylmethionine; Sensation Disorders; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
CblE type of homocystinuria due to methionine synthase reductase deficiency: clinical and molecular studies and prenatal diagnosis in two families.
Topics: Adult; Anemia, Megaloblastic; Base Sequence; Cells, Cultured; Child; Chromatography, Ion Exchange; DNA; Female; Ferredoxin-NADP Reductase; Fibroblasts; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Molecular Sequence Data; Mutation; Prenatal Diagnosis; Reverse Transcriptase Polymerase Chain Reaction; Serine; Vitamin B 12 | 2002 |
Alcohol, folate, methionine, and risk of incident breast cancer in the American Cancer Society Cancer Prevention Study II Nutrition Cohort.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; American Cancer Society; Breast Neoplasms; Cohort Studies; Eating; Ethanol; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Methionine; Middle Aged; Multivariate Analysis; Postmenopause; Prospective Studies; Risk Factors; Solvents; Statistics as Topic; United States; Women's Health | 2003 |
Relationship of folate, vitamin B-6, vitamin B-12, and methionine intake to incidence of colorectal cancers.
Topics: Aged; Alcohol Drinking; Cohort Studies; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Humans; Incidence; Iowa; Methionine; Middle Aged; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2002 |
Soy product intake is inversely associated with serum homocysteine level in premenopausal Japanese women.
Topics: Adult; Diet; Female; Folic Acid; Glycine max; Homocysteine; Humans; Isoflavones; Methionine; Middle Aged; Nutritional Status; Premenopause; Soybean Proteins; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2003 |
Hyperhomocysteinemia in cerebral vein thrombosis.
Topics: Adolescent; Adult; Case-Control Studies; Child; Female; Folic Acid; Homocystine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Thrombophilia; Venous Thrombosis; Vitamin B 12 | 2003 |
Determinants of hyperhomocysteinemia in patients with chronic liver disease and after orthotopic liver transplantation.
Topics: Adult; Area Under Curve; Case-Control Studies; Chronic Disease; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases; Liver Transplantation; Male; Metabolic Clearance Rate; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2003 |
Combination therapy with folic acid and methionine in the prevention of retinoic acid-induced cleft palate in mice.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cleft Palate; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Injections, Intraperitoneal; Methionine; Mice; Pregnancy; Teratogens; Tretinoin | 2003 |
Severe methylenetetrahydrofolate reductase deficiency, methionine synthase, and nitrous oxide--a cautionary tale.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Anesthetics, Inhalation; Folic Acid; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nitrous Oxide; Oxidoreductases; Point Mutation | 2003 |
Adverse effect of nitrous oxide in a child with 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Anesthetics, Inhalation; Cells, Cultured; DNA Mutational Analysis; Fatal Outcome; Fibroblasts; Folic Acid; Genes, Recessive; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Infant; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nitrous Oxide; Oxidoreductases; Point Mutation; Polymorphism, Genetic; RNA | 2003 |
Plasma thiols and their determinants in phenylketonuria.
Topics: Adolescent; Cross-Sectional Studies; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Methionine; Phenylalanine; Phenylketonurias; Sulfhydryl Compounds; Vitamin B 12 | 2003 |
Methionine restriction selectively targets thymidylate synthase in prostate cancer cells.
Topics: Antimetabolites, Antineoplastic; Cell Division; Fluorouracil; Folic Acid; Humans; Male; Methionine; Nucleotides; Prostatic Neoplasms; Thymidylate Synthase; Tumor Cells, Cultured | 2003 |
Combined marginal folate and riboflavin status affect homocysteine methylation in cultured immortalized lymphocytes from persons homozygous for the MTHFR C677T mutation.
Topics: Cell Transformation, Viral; Cells, Cultured; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Lymphocytes; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Riboflavin; Tetrahydrofolates | 2003 |
Effects of reducing dietary protein, methionine, choline, folic acid, and vitamin B12 during the late stages of the egg production cycle on performance and eggshell quality.
Topics: Animal Feed; Animal Husbandry; Animals; Chickens; Choline; Dietary Proteins; Egg Shell; Female; Folic Acid; Methionine; Ovum; Vitamin B 12 | 2003 |
Homocysteine accumulates in supernatants of stimulated human peripheral blood mononuclear cells.
Topics: Cells, Cultured; Concanavalin A; Folic Acid; Homocysteine; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Methionine; Phytohemagglutinins; Pokeweed Mitogens; Statistics, Nonparametric | 2003 |
[Therapeutic use of the combination of methionine with folic acid in precirrhotic cases, under laboratory control; study based on 23 cases].
Topics: Folic Acid; Humans; Liver Cirrhosis; Methionine | 1953 |
Non-participation of folic acid in the biosynthesis of methyl compounds from precursors.
Topics: Biochemical Phenomena; Choline; Coenzymes; Folic Acid; Methionine | 1954 |
Methionine-vitamin B therapy; effect of a supplement of methionine and vitamin B on pregnancy and prematurity.
Topics: Eclampsia; Female; Folic Acid; Humans; Infant; Infant, Newborn; Infant, Premature; Methionine; Pre-Eclampsia; Pregnancy; Vitamin B Complex; Vitamins | 1955 |
Incorporation of serine-3-C14 and formaldehyde-C14 into methionine in vitro. I. Role of folic acid.
Topics: Biochemical Phenomena; Folic Acid; Folic Acid Deficiency; Formaldehyde; Humans; In Vitro Techniques; Liver; Methionine; Serine | 1957 |
Vitamin B12 and folic acid in relation to methionine synthesis from betaine in vivo and invitro.
Topics: Betaine; Choline; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 1957 |
Methionine, homocystine, choline, folic acid and vitamin B12 in the nutrition of the mouse.
Topics: Animals; Choline; Cystine; Folic Acid; Homocystine; Humans; Methionine; Mice; Nutritional Status; Vitamin B 12 | 1959 |
Folic acid and the synthesis of methionine by extracts of Escherichia coli.
Topics: Escherichia coli; Folic Acid; Methionine | 1961 |
Metabolism of formiminoglutamic acid by vitamin B12 and folic acid-deficient rats fed excess methionine.
Topics: Animals; Corrinoids; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Glutamates; Methionine; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1960 |
Folic acid and labile methyl oxidation.
Topics: Diet; Folic Acid; Humans; Methionine; Nutrition Assessment; Nutritional Status; Oxidation-Reduction | 1960 |
[On the treatment of skin diseases associated with liver disorders].
Topics: Choline; Folic Acid; Humans; Liver Diseases; Methionine; Skin Diseases; Vitamin B Complex | 1961 |
Excretion of formiminoglutamic acid as an index of vitamin B12, folic acid, and methionine deficiencies.
Topics: Corrinoids; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Glutamates; Hematinics; Humans; Methionine; Vitamin B 12; Vitamin B 12 Deficiency | 1961 |
Analogues of folic acid and the activity of dihydrofolic acids in the synthesis of methionine by Escherichia coli.
Topics: Escherichia coli; Folic Acid; Folic Acid Antagonists; Humans; Methionine | 1962 |
Enzymatic synthesis of the methyl group of methionine. V. Studies with 5, 10-methylenetetrahydrofolate reductase from Escherichia coli.
Topics: Escherichia coli; Folic Acid; Methionine; Methylenetetrahydrofolate Reductase (NADPH2) | 1963 |
EFFECT OF OROTIC ACID ON THE SYNTHESIS OF CITROVORUM FACTOR AND OF METHIONINE IN LIVER OF THE CHICK.
Topics: Animals; Chickens; Corrinoids; Folic Acid; Leuconostoc; Leucovorin; Liver; Meat; Metabolism; Methionine; Orotic Acid; Pharmacology; Poultry; Proteins; Research; Vitamin B 12 | 1963 |
EFFECT OF VITAMIN B12 ANALOGUES ON METHIONINE FORMATION FROM N5-METHYLTETRAHYDROFOLIC ACID.
Topics: Carbon Isotopes; Corrinoids; Escherichia coli; Folic Acid; Homocysteine; Methionine; Pharmacology; Proteins; Research; Sulfhydryl Compounds; Vitamin B 12 | 1964 |
[HISTOLOGICAL STUDY ON NUCLEIC ACIDS OF THE LIVER IN DIETARY LIVER DISORDERS. 2. THE RESULTS IN THE GROUPS FED BUCKWHEAT WITH ANTI-FATTY LIVER AGENTS].
Topics: Animals; Caseins; Diet; Edible Grain; Fagopyrum; Fatty Liver; Folic Acid; Liver; Methionine; Mice; Nutrition Disorders; Orotic Acid; Research; RNA; Thiamine; Thioctic Acid; Vitamin B Complex | 1964 |
OROTIC ACID AND METABOLISM OF ONE CARBON UNIT: CONVERSION OF FOLIC ACID TO CITROVORUM FACTOR AND METHIONINE SYNTHESIS IN CHICK LIVER.
Topics: Animals; Carbon; Chickens; Folic Acid; Homocysteine; Leuconostoc; Leucovorin; Liver; Metabolism; Methionine; Orotic Acid; Poultry; Proteins; Research; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1963 |
ORGAN AND INTRACELLULAR LOCATION OF THE METHIONINE METHYL GROUP SYNTHESIZING SYSTEM OF THE RAT.
Topics: Adenosine Triphosphate; Brain; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Glucose; Homocysteine; Kidney; Leuconostoc; Liver; Magnesium; Methionine; Muscles; NAD; Pectoralis Muscles; Proteins; Pyridoxal Phosphate; Rats; Research; Serine; Spectrophotometry | 1964 |
THE ROLE OF VITAMIN B12 IN METHYL TRANSFER TO HOMOCYSTEINE.
Topics: Chromatography; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; Magnesium Sulfate; Mercaptoethanol; Methionine; Nucleosides; Pharmacology; Proteins; Research; Spectrophotometry; Sulfhydryl Compounds; Vitamin B 12 | 1964 |
STUDIES ON THE ROLE OF VITAMIN B12 FOR THE SYNTHESIS OF METHIONINE IN LIVER.
Topics: Animals; Carbon Isotopes; Chromatography; Folic Acid; Liver; Meat; Methionine; Pharmacology; Poultry; Proteins; Rats; Research; Swine; Vitamin B 12; Vitamin B 12 Deficiency | 1964 |
THE FUNCTION OF FOLIC ACID IN CELLULAR METABOLISM.
Topics: Biochemical Phenomena; Biochemistry; Celiac Disease; Diet; Folic Acid; Folic Acid Deficiency; Glutamates; Intestines; Metabolism; Methionine; Nucleotides; Purines; Sprue, Tropical; Sulfonamides | 1964 |
STUDIES ON THE ENZYMATIC N- AND O-DEMETHYLATION OF NARCOTIC ANALGESICS AND EVIDENCE FOR THE FORMATION OF CODEINE FROM MORPHINE IN RATS AND DOGS.
Topics: Adenosine Triphosphate; Antitussive Agents; Autoradiography; Carbon Isotopes; Chlorides; Chromatography; Codeine; Dogs; Folic Acid; Glutathione; Liver; Metabolism; Methionine; Methylation; Morphine; NADP; Narcotics; Pharmacology; Rats; Research; Urine | 1964 |
AMINOPTERIN FOR PSORIASIS. A DECADE'S OBSERVATION.
Topics: Adrenocorticotropic Hormone; Alanine Transaminase; Aminopterin; Drug Therapy; Folic Acid; Geriatrics; Humans; Kidney Function Tests; Liver Function Tests; Methionine; Methotrexate; Prednisolone; Pregnancy; Psoriasis; Toxicology; Triamcinolone | 1964 |
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. VII. ISOLATION OF A COBALAMIN-CONTAINING TRANSMETHYLASE (5-METHYLTETRAHYDRO-FOLATE-HOMOCYSTEINE) FROM MAMMALIAN LIVER.
Topics: Animals; Chromatography; Corrinoids; Flavin-Adenine Dinucleotide; Folic Acid; Glutamates; Homocysteine; Liver; Methionine; Methyltransferases; NAD; NADP; Protamines; Research; Swine; Transferases; Vitamin B 12 | 1964 |
THE ROLE OF ADENOSYLMETHIONINE AND 5-METHYLTETRAHYDROFOLATE IN THE REGULATION OF THE METABOLISM OF SINGLE CARBON UNITS.
Topics: Anemia; Anemia, Macrocytic; Carbon; Folic Acid; Humans; Metabolism; Methionine; Nucleosides; Tetrahydrofolates; Vitamin B 12 | 1964 |
EFFECT OF WATER-SOLUBLE VITAMINS ON RAT DIAPHRAGM CARBOHYDRATE METABOLISM.
Topics: 4-Aminobenzoic Acid; Ascorbic Acid; Carbohydrate Metabolism; Diaphragm; Folic Acid; Inositol; Leucovorin; Metabolism; Methionine; Muscles; Pantothenic Acid; Pharmacology; Pyridoxine; Rats; Research; Vitamins | 1964 |
THE ROLE OF VITAMIN B12 IN METHIONINE BIOSYNTHESIS IN AVIAN LIVER.
Topics: Amino Acids; Animals; Birds; Coenzymes; Corrinoids; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Folic Acid; Homocysteine; Liver; Methionine; Poultry; Research; Transferases; Vitamin B 12 | 1964 |
THE FATE OF CARBON-19 IN THE COURSE OF OESTROGEN BIOSYNTHESIS FROM TESTOSTERONE-19-14C.
Topics: Carbon; Carbon Dioxide; Carbon Isotopes; Cyanides; Estradiol Congeners; Estrogens; Folic Acid; Formaldehyde; Formates; Lipogenesis; Magnesium; Metabolism; Methionine; Serine; Testosterone | 1965 |
REDUCTION AND ALKYLATION OF THE COBAMIDE PROSTHETIC GROUP IN THE ENZYMATIC SYNTHESIS OF METHIONINE.
Topics: Alkylating Agents; Alkylation; Amino Acids; Cobalt; Cobamides; Escherichia coli; Folic Acid; Histocytochemistry; Metabolism; Methionine; Transferases | 1965 |
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. 8. REPRESSION-DEREPRESSION, PURIFICATION, AND PROPERTIES OF 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE FROM ESCHERICHIA COLI.
Topics: Alkylation; Amino Acids; Anemia; Anemia, Pernicious; Biochemical Phenomena; Biochemistry; Chemistry Techniques, Analytical; Chromatography; Enzyme Inhibitors; Enzyme Repression; Escherichia coli; Feedback; Flavin-Adenine Dinucleotide; Folic Acid; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases; Research; Spectrophotometry; Tetrahydrofolates; Vitamin B 12 | 1965 |
ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. IX. TRANSMETHYLATION FROM S-ADENOSYLMETHIONINE AND 5-METHYLTETRAHYDROFOLATE TO 2-MERCAPTOETHANOL AND HOMOCYSTEINE.
Topics: Alkylation; Biological Assay; Carbon Isotopes; Folic Acid; Homocysteine; Kinetics; Lactobacillus; Mercaptoethanol; Methionine; Nucleosides; Research; S-Adenosylmethionine; Spectrophotometry; Sulfhydryl Compounds; Tetrahydrofolates; Transferases | 1965 |
STUDIES ON METHIONINE BIOSYNTHESIS. EFFECT OF ALKYLCOBAMIDE DERIVATIVES ON THE FORMATION OF HOLOENZYME.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Corrinoids; Dinitrophenols; Enzyme Inhibitors; Escherichia coli; Folic Acid; Holoenzymes; Homocysteine; Light; Metabolism; Methionine; Research; Transferases; Vitamin B 12 | 1965 |
VITAMIN REQUIREMENTS OF SEVERAL CELLULOLYTIC RUMEN BACTERIA.
Topics: 4-Aminobenzoic Acid; Amino Acids; Animals; Bacteria; Bacteroides; Biotin; Caseins; Cattle; Cellulose; Culture Media; Fermentation; Fibrobacter; Folic Acid; Metabolism; Methionine; Protein Hydrolysates; Research; Rumen; Ruminococcus; Vitamin B 12; Vitamin B Complex; Vitamins | 1965 |
A MECHANISM OF HYPERTROPHY AND WEAR OF THE MYOCARDIUM.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Aortic Valve Stenosis; Cardiomegaly; Cardiomyopathies; DNA; Dogs; Folic Acid; Humans; Hypertrophy; Methionine; Muscle Proteins; Myocardium; Nucleic Acids; Nucleosides; Orotic Acid; Pharmacology; Rabbits; Rats; Research; Strophanthins; Vitamin B 12 | 1965 |
THE EFFECTS OF CHOLINE AND RELATED COMPOUNDS ON THE GROWTH AND DEVELOPMENT OF DROSOPHILA MELANOGASTER.
Topics: Amino Acids; Amino Alcohols; Ammonium Compounds; Animals; Betaine; Carnitine; Chemical Phenomena; Chemistry; Choline; Diet; Drosophila; Drosophila melanogaster; Fatty Liver; Folic Acid; Growth and Development; Meat; Metamorphosis, Biological; Methionine; Neurospora; Pharmacology; Poultry; Quaternary Ammonium Compounds; Rats; Research; Salts; Vitamin B Complex | 1965 |
INTERRELATIONS BETWEEN TWO PATHWAYS OF METHIONINE BIOSYNTHESIS IN AEROBACTER AEROGENES.
Topics: Amino Acids; Biochemical Phenomena; Chemistry Techniques, Analytical; Corrinoids; Culture Media; Enterobacter aerogenes; Enzyme Inhibitors; Escherichia coli; Folic Acid; Metabolism; Methionine; Pharmacology; Research; Transferases; Vitamin B 12 | 1965 |
Interrelationships between folic acid and cobalamin in the synthesis of methionine by extracts of Escherichia coli.
Topics: Escherichia coli; Folic Acid; Humans; Methionine; Vitamin B 12 | 1960 |
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor.
Topics: Adult; Carbon; Carbon Isotopes; Female; Folic Acid; Homocysteine; Humans; Leucine; Methionine; Methylation; Reference Values; Serine | 2004 |
Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes.
Topics: Adult; Aged; Cell Death; Cell Division; Cell Nucleus; Cells, Cultured; Culture Media; Female; Folic Acid; Gene Rearrangement; Genomic Instability; Homocysteine; Homozygote; Humans; Lymphocytes; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Polymorphism, Genetic; Riboflavin | 2004 |
Plasma homocysteine after insulin infusion in type II diabetic patients with and without methionine intolerance.
Topics: Blood Glucose; Cysteine; Diabetes Mellitus, Type 2; DNA; Female; Folic Acid; Glucose Clamp Technique; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymerase Chain Reaction; Vitamin B 12; Vitamin B 6 | 2004 |
The influence of folic acid on methionine metabolism.
Topics: Folic Acid; Humans; Methionine | 1951 |
Influence of vitamin B12 and folacin on the synthesis of choline and methionine by the rat.
Topics: Animals; Biochemical Phenomena; Choline; Corrinoids; Folic Acid; Hematinics; Methionine; Rats; Vitamin B 12 | 1951 |
Prevention of DL-methionine toxicity in rats by vitamins E, B12, folacin, glycine and arginine.
Topics: Animals; Arginine; Atropine; Corrinoids; Folic Acid; Glycine; Glycine Agents; Hematinics; Methionine; Rats; Vitamin B 12; Vitamin B Complex; Vitamin E; Vitamins | 1951 |
[Contribution to the study of pellagra].
Topics: Choline; Folic Acid; Humans; Methionine; Pellagra; Vitamin B Complex | 1951 |
Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia.
Topics: Animals; Ascorbic Acid; Blotting, Western; Diet; Folic Acid; Glutathione; Hepatocytes; Homeostasis; Homocysteine; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; tert-Butylhydroperoxide; Tissue Distribution | 2004 |
Mild hyperhomocysteinemia induced by feeding rats diets rich in methionine or deficient in folate promotes early atherosclerotic inflammatory processes.
Topics: Animals; Aorta; Arteriosclerosis; Chemokine CCL2; Diet; Endothelium, Vascular; Folic Acid; Folic Acid Deficiency; Hyperhomocysteinemia; Inflammation; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Methionine; NF-kappa B; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2004 |
Young stroke and basal plasma and post-methionine load homocysteine and cysteine levels 1 year after the acute event: do plasma folates make the difference?
Topics: Adult; Case-Control Studies; Cysteine; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Middle Aged; Stroke; Time Factors; Vitamin B 12 | 2004 |
Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Female; Folic Acid; Germany; Homocysteine; Humans; Life Style; Linear Models; Longitudinal Studies; Male; Methionine; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Sex Characteristics; Smoking; Tea; Vitamin B 12 | 2004 |
Oxidative stress in mothers who have conceived fetus with neural tube defects: the role of aminothiols and selenium.
Topics: Adult; Case-Control Studies; Cysteine; Dipeptides; Female; Folic Acid; Glutathione; Homocysteine; Humans; Infant, Newborn; Methionine; Mothers; Neural Tube Defects; Oxidation-Reduction; Oxidative Stress; Selenium; Sulfhydryl Compounds | 2004 |
Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Arabidopsis; Binding Sites; Cations; Crystallography, X-Ray; Cysteine; Escherichia coli; Folic Acid; Fourier Analysis; Histidine; Homocysteine; Methionine; Methyltransferases; Models, Molecular; Plasmids; Protein Conformation; Protein Structure, Tertiary; Sulfur; Tetrahydrofolates; Vitamin B 12; Zinc | 2004 |
Inhibition of growth of Lactobacillus casei by methionine and its relation to folic acid assimilation.
Topics: Bacteria; Biological Phenomena; Folic Acid; Humans; Lacticaseibacillus casei; Methionine | 1950 |
A mathematical model of the folate cycle: new insights into folate homeostasis.
Topics: Allosteric Site; Animals; Dose-Response Relationship, Drug; Folic Acid; Homeostasis; Humans; Kinetics; Liver; Methionine; Methotrexate; Models, Biological; Models, Chemical; Models, Theoretical; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidylate Synthase; Time Factors; Up-Regulation; Vitamin B 12 Deficiency | 2004 |
Pro-oxidant activity and methionine metabolism in chronic alcohol abusers: relationship to alcohol withdrawal and folate administration.
Topics: Adult; Alcoholism; Case-Control Studies; Chronic Disease; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Reactive Oxygen Species; Temperance | 2004 |
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6 | 2005 |
Polymorphism in folate- and methionine-metabolizing enzyme and aberrant CpG island hypermethylation in uterine cervical cancer.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acid Anhydride Hydrolases; Cadherins; Case-Control Studies; CpG Islands; DNA Methylation; Female; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Proteins; Polymorphism, Genetic; Uterine Cervical Neoplasms | 2005 |
Effect of folic acid on methionine and homocysteine metabolism in end-stage renal disease.
Topics: Administration, Oral; Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Male; Methionine; Methylation; Middle Aged; Renal Dialysis | 2005 |
Folic acid treatment increases homocysteine remethylation and methionine transmethylation in healthy subjects.
Topics: Adult; Amino Acids; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Methylation; Middle Aged; Vitamins | 2005 |
Effects of dietary supplements of folic acid and rumen-protected methionine on lactational performance and folate metabolism of dairy cows.
Topics: Animals; Cattle; Cysteine; Diet; Dietary Supplements; Female; Folic Acid; Hemoglobins; Homocysteine; Kinetics; Lactation; Methionine; Milk; Rumen; Vitamin B 12 | 2005 |
Effects of intramuscular injections of vitamin B12 on lactation performance of dairy cows fed dietary supplements of folic acid and rumen-protected methionine.
Topics: Animals; Cattle; Cysteine; Diet; Dietary Supplements; Eating; Female; Folic Acid; Homocysteine; Injections, Intramuscular; Lactation; Methionine; Methylmalonic Acid; Milk; Parity; Rumen; Vitamin B 12 | 2005 |
Folate-induced reversal of leukoencephalopathy and intellectual decline in methylene-tetrahydrofolate reductase deficiency: variable response in siblings.
Topics: Activities of Daily Living; Adolescent; Adult; Betaine; Brain; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Homocystinuria; Humans; Intelligence; Leukoencephalopathy, Progressive Multifocal; Long-Term Care; Magnetic Resonance Imaging; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neurologic Examination; Treatment Outcome | 2005 |
Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model.
Topics: Animals; CHO Cells; CpG Islands; Cricetinae; Cricetulus; DNA Methylation; DNA, Satellite; Folic Acid; Humans; Methionine; Mice; NIH 3T3 Cells; Promoter Regions, Genetic; Tumor Cells, Cultured | 2005 |
MTX-induced white matter changes are associated with polymorphisms of methionine metabolism.
Topics: Aged; Brain; Central Nervous System Neoplasms; Demyelinating Diseases; DNA Mutational Analysis; Drug Resistance; Female; Folic Acid; Folic Acid Antagonists; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Haplotypes; Humans; Lymphoma; Male; Methionine; Methotrexate; Middle Aged; Myelin Sheath; Nerve Fibers, Myelinated; Neurotoxins; Polymorphism, Genetic; Risk Factors; S-Adenosylmethionine | 2005 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes.
Topics: Aged; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Folic Acid; Homocysteine; Humans; Kidney; Kidney Failure, Chronic; Male; Methionine; Methylmalonic Acid; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Transcobalamins; Vitamin B 12; Vitamin B 6 | 2005 |
Methimazole-induced hypothyroidism paradoxically decreases homocysteine.
Topics: Adolescent; Adult; Female; Fibrinogen; Folic Acid; Homocysteine; Humans; Hypothyroidism; Lipids; Logistic Models; Male; Methimazole; Methionine; Plasminogen Activator Inhibitor 1; Thyrotropin; Vitamin B 12; Vitamin B 6 | 2005 |
Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer.
Topics: Aged; Alcohol Drinking; Case-Control Studies; Colonic Neoplasms; Diet; Female; Folic Acid; Genotype; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Rectal Neoplasms | 2005 |
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
Topics: Adult; Amino Acids; Female; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Leucine; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Serine | 2005 |
Prevalence and mechanisms of hyperhomocysteinemia in chronic alcoholics.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcoholism; Avitaminosis; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methionine; Methylation; Middle Aged; Prevalence | 2005 |
Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice.
Topics: Animals; Diet; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Heart Defects, Congenital; Homocysteine; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Pregnancy | 2005 |
Diet-dependent survival of protein repair-deficient mice.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Brain; Eating; Folic Acid; Methionine; Mice; Mice, Mutant Strains; Protein D-Aspartate-L-Isoaspartate Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures; Survival Rate | 2005 |
[Folate reduces monocyte chemoattractant protein-1 expression in rats with hyperhomocysteinemia].
Topics: Animals; Aorta; Chemokine CCL2; Endothelium, Vascular; Folic Acid; Homocysteine; Hyperhomocysteinemia; Leukocytes, Mononuclear; Male; Methionine; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Dietary determinants of one-carbon metabolism and the risk of non-Hodgkin's lymphoma: NCI-SEER case-control study, 1998-2000.
Topics: Adult; Aged; Alcohol Drinking; Carbon; Case-Control Studies; Confidence Intervals; Diet; Dietary Fiber; Dietary Supplements; Feeding Behavior; Female; Folic Acid; Humans; Logistic Models; Lymphoma, Non-Hodgkin; Male; Methionine; Middle Aged; Multivariate Analysis; Odds Ratio; Risk Factors; SEER Program; United States; Vitamin B Complex | 2005 |
Folate intake and squamous-cell carcinoma of the oesophagus in Italian and Swiss men.
Topics: Alcohol Drinking; Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Folic Acid; Humans; Italy; Male; Methionine; Middle Aged; Switzerland; Vitamin B 6 | 2006 |
Moderate hyperhomocysteinemia and early-onset central retinal vein occlusion.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxal Phosphate; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2006 |
Implication of the folate-methionine metabolism pathways in susceptibility to follicular lymphomas.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; DNA; Enzymes; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Glycine Hydroxymethyltransferase; Humans; Lymphoma, Follicular; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymorphism, Genetic; Risk Factors; Thymidylate Synthase | 2006 |
[The effect of methyl-containing supplements during pregnancy on the phenotypic modification of offspring hair color in rats].
Topics: Agouti Signaling Protein; Animals; Betaine; Choline; Color; Dietary Supplements; Electron Spin Resonance Spectroscopy; Female; Folic Acid; Hair Color; Heterozygote; Homozygote; Intercellular Signaling Peptides and Proteins; Male; Methionine; Phenotype; Pigments, Biological; Pregnancy; Rats; Vitamin B 12; Zinc | 2006 |
Intake of folate and related nutrients in relation to risk of epithelial ovarian cancer.
Topics: Adult; Data Interpretation, Statistical; Diet; Female; Folic Acid; Humans; Incidence; Methionine; Middle Aged; Ovarian Neoplasms; Prospective Studies; Risk Factors; Surveys and Questionnaires; United States; Vitamin B 6 | 2006 |
Excess methionine suppresses the methylation cycle and inhibits neural tube closure in mouse embryos.
Topics: Animals; Azacitidine; Embryo Culture Techniques; Embryo, Mammalian; Folic Acid; Methionine; Methylation; Mice; Neural Tube Defects; Phenotype | 2006 |
Is elevated post-methionine load homocysteinaemia a risk factor for cervical artery dissection?
Topics: Adult; Carotid Artery, Internal; Carotid Artery, Internal, Dissection; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Methionine; Risk Factors; Up-Regulation; Vertebral Artery Dissection | 2006 |
The association between atopy and factors influencing folate metabolism: is low folate status causally related to the development of atopy?
Topics: Adult; Cross-Sectional Studies; Diet; Female; Folic Acid; Genotype; Homocysteine; Humans; Hypersensitivity; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Polymorphism, Genetic; Riboflavin; Risk Assessment; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2006 |
Modification of p53 protein profile by gamma irradiation followed by methyl donor starvation.
Topics: Animals; Cell Nucleus; Choline; Comet Assay; Cytoplasm; DNA Damage; DNA Methylation; DNA Repair; Dose-Response Relationship, Radiation; Folic Acid; Gamma Rays; Liver; Male; Methionine; Mice; Spleen; Thymus Gland; Tumor Suppressor Protein p53 | 2006 |
Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study.
Topics: Aged; Cohort Studies; Cystathionine beta-Synthase; Female; Folic Acid; Heterozygote; Homocysteine; Humans; Male; Methionine; Middle Aged; Minisatellite Repeats; Nuclear Family; Vitamin B 12; Vitamin B 6 | 2006 |
Genetic polymorphism of folate and methionine metabolizing enzymes and their susceptibility to malignant lymphoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Child; Child, Preschool; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Lymphoma; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic | 2005 |
Modulation of DNA methyltransferase profile by methyl donor starvation followed by gamma irradiation.
Topics: Animals; Cell Nucleus; Choline; Comet Assay; Cytoplasm; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; DNA Repair; Dose-Response Relationship, Radiation; Folic Acid; Gamma Rays; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; S-Adenosylmethionine | 2007 |
Body composition: an important determinant of homocysteine and methionine concentrations in healthy individuals.
Topics: Adipose Tissue; Adult; Body Composition; Body Water; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Menopause; Methionine; Middle Aged; Muscle, Skeletal; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Mid-trimester amniotic fluid methionine concentrations: a predictor of birth weight and length.
Topics: Amniotic Fluid; Birth Weight; Body Height; Body Size; Female; Fetal Development; Folic Acid; Humans; Infant, Newborn; Male; Methionine; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Second; Vitamin B 12 | 2006 |
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
Topics: Betaine; Carbon; DNA Methylation; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Kinetics; Mathematics; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Molecular Biology; Nutritional Physiological Phenomena; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polymorphism, Genetic; S-Adenosylmethionine; Vitamin B 12 Deficiency | 2006 |
No effect of folic acid and methionine supplementation on D4Z4 methylation in patients with facioscapulohumeral muscular dystrophy.
Topics: Adolescent; Adult; Alleles; Case-Control Studies; Dietary Supplements; DNA; DNA Methylation; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Muscle, Skeletal; Muscular Dystrophy, Facioscapulohumeral; Oligonucleotide Array Sequence Analysis; Pilot Projects | 2006 |
Dietary factors of one-carbon metabolism and prostate cancer risk.
Topics: Aged; Alcohol Drinking; alpha-Tocopherol; beta Carotene; Carbon; Case-Control Studies; Dietary Supplements; Double-Blind Method; Ethanol; Finland; Folic Acid; Humans; Male; Methionine; Middle Aged; One-Carbon Group Transferases; Proportional Hazards Models; Prospective Studies; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Smoking; Vitamin B 12; Vitamin B 6 | 2006 |
Medium-term methionine supplementation increases plasma homocysteine but not ADMA and improves blood pressure control in rats fed a diet rich in protein and adequate in folate and choline.
Topics: Adaptation, Physiological; Animals; Area Under Curve; Arginine; Blood Pressure; Choline; Dietary Proteins; Dietary Supplements; Folic Acid; Homocysteine; Male; Methionine; Methylation; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Time Factors | 2006 |
Dietary folate consumption and risk of ovarian cancer: a prospective cohort study.
Topics: Adult; Alcohol Drinking; Canada; Cohort Studies; Diet; Female; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Middle Aged; Ovarian Neoplasms; Proportional Hazards Models; Prospective Studies; Risk | 2006 |
In silico experimentation with a model of hepatic mitochondrial folate metabolism.
Topics: Animals; Cytosol; Dose-Response Relationship, Drug; Folic Acid; Glycine; Glycine Hydroxymethyltransferase; Humans; Methionine; Mitochondria, Liver; Models, Biological; Osmolar Concentration; Proteins; Serine; Tetrahydrofolates | 2006 |
Colorectal cancer protective effects and the dietary micronutrients folate, methionine, vitamins B6, B12, C, E, selenium, and lycopene.
Topics: Antioxidants; Ascorbic Acid; Carotenoids; Case-Control Studies; Colorectal Neoplasms; Diet; Diet Surveys; DNA Methylation; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Lycopene; Male; Methionine; Micronutrients; Odds Ratio; Risk Factors; Selenium; Survival Analysis; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin E; Vitamins | 2006 |
Dietary intake of folate and co-factors in folate metabolism, MTHFR polymorphisms, and reduced rectal cancer.
Topics: Adult; Aged; Alcohol Drinking; California; Case-Control Studies; Diet; Diet Surveys; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Logistic Models; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Rectal Neoplasms; Riboflavin; Risk; Utah; Vitamin B 12; Vitamin B 6 | 2007 |
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.
Topics: Animals; Brain; Disease Models, Animal; Embryo, Mammalian; Female; Ferredoxin-NADP Reductase; Folic Acid; Heart; Homocysteine; Hyperhomocysteinemia; Kidney; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Hyperhomocysteinemia and low methionine stress are risk factors for central retinal venous occlusion in an Indian population.
Topics: Adult; Case-Control Studies; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methionine; Prevalence; Prospective Studies; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2007 |
Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses' Health Study.
Topics: Adenoma; Adult; Alcohol Drinking; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetics, Population; Humans; Methionine; Middle Aged; One-Carbon Group Transferases; Polymorphism, Single Nucleotide; Prospective Studies; Risk; Transcobalamins; Vitamin B 12 | 2007 |
Low vitamin B6, and not plasma homocysteine concentration, as risk factor for abdominal aortic aneurysm: a retrospective case-control study.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Case-Control Studies; Creatinine; DNA Mutational Analysis; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency | 2007 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects.
Topics: Betaine; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Methionine; Methylation; Neural Tube Defects; Nutritional Physiological Phenomena; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B Complex | 2007 |
Supranormal dietary folic acid supplementation: effects on methionine metabolism in weanling rats.
Topics: Animals; Biomarkers; Dietary Supplements; DNA Methylation; Folic Acid; Homocysteine; Liver; Male; Methionine; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamins; Weaning | 2007 |
Folate deficiency during pregnancy impacts on methyl metabolism without affecting global DNA methylation in the rat fetus.
Topics: Amino Acids; Animals; Choline; Diet; DNA Methylation; Female; Fetus; Folic Acid; Folic Acid Deficiency; Liver; Maternal-Fetal Exchange; Metabolic Networks and Pathways; Methionine; Phosphorylcholine; Pregnancy; Pregnancy Complications; Rats; Weight Gain | 2007 |
Conformational change of the methionine 20 loop of Escherichia coli dihydrofolate reductase modulates pKa of the bound dihydrofolate.
Topics: Binding Sites; Computer Simulation; Crystallography, X-Ray; Escherichia coli Proteins; Folic Acid; Kinetics; Methionine; Models, Molecular; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase | 2007 |
Consumption of folate-related nutrients and metabolism of arsenic in Bangladesh.
Topics: Adult; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Choline; Cysteine; Dietary Proteins; Dose-Response Relationship, Drug; Environmental Exposure; Female; Folic Acid; Humans; Male; Methionine; Methylation; Middle Aged; Multivariate Analysis; Niacin; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex; Water Pollutants, Chemical | 2007 |
Low intake of vitamin B-6 is associated with increased risk of colorectal cancer in Japanese men.
Topics: Aged; Alcoholic Beverages; Colorectal Neoplasms; Diet; Diet Surveys; Female; Folic Acid; Follow-Up Studies; Humans; Japan; Male; Methionine; Middle Aged; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
The use of an in vivo model to study the effects of hyperhomocysteinaemia on vascular function.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Folic Acid; Hyperhomocysteinemia; Male; Methionine; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
One-carbon metabolism, colorectal carcinogenesis, chemoprevention--with caution.
Topics: Animals; Betaine; Carbon; Cell Transformation, Neoplastic; Chemoprevention; Choline; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine | 2007 |
Methylation status in females with rett syndrome.
Topics: Adolescent; Adult; Child; Child, Preschool; Creatine; Female; Folic Acid; Humans; Methionine; Methyl-CpG-Binding Protein 2; Methylation; Rett Syndrome | 2007 |
Regulation of one-carbon metabolism in Arabidopsis: the N-terminal regulatory domain of cystathionine gamma-synthase is cleaved in response to folate starvation.
Topics: Amino Acid Sequence; Arabidopsis; Carbon; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Cells, Cultured; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Plant; Methionine; Molecular Sequence Data | 2007 |
S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet.
Topics: Animals; Body Weight; Disease Models, Animal; Ethanol; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Linear Models; Liver; Liver Diseases, Alcoholic; Male; Methionine; Necrosis; Oxidative Stress; S-Adenosylmethionine; Swine; Swine, Miniature | 2007 |
Experimental hyperhomocysteinemia disturbs bone metabolism in rats.
Topics: Animals; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Collagen Type I; Creatine; Female; Folic Acid; Homocysteine; Hydroxyproline; Hyperhomocysteinemia; Methionine; Osteocalcin; Osteogenesis; Peptides; Rats; Rats, Wistar; Vitamin B 12 | 2007 |
High folic acid increases cell turnover and lowers differentiation and iron content in human HT29 colon cancer cells.
Topics: Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Dietary Supplements; Epithelial Cells; Folic Acid; Gene Expression Profiling; HT29 Cells; Humans; Iron; Methionine; Oligonucleotide Array Sequence Analysis; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex | 2008 |
Nutrients contributing to one-carbon metabolism and risk of non-Hodgkin lymphoma subtypes.
Topics: Carbon; Case-Control Studies; Diet; Diet Surveys; Female; Folic Acid; Humans; Logistic Models; Lymphoma, Non-Hodgkin; Methionine; Middle Aged; Multivariate Analysis; Riboflavin; Risk Factors; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2008 |
DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status.
Topics: Animals; Animals, Newborn; Blood Pressure; Body Composition; Diet; DNA Methylation; Embryo, Mammalian; Epigenesis, Genetic; Female; Fertilization; Folic Acid; Glucose; Heart Rate; Immunity; Insulin Resistance; Methionine; Pregnancy; Pregnancy Outcome; Sheep; Vitamin B 12; Vitamin B Complex | 2007 |
Plasma S-adenosylhomocysteine is a better biomarker of atherosclerosis than homocysteine in apolipoprotein E-deficient mice fed high dietary methionine.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Body Weight; Diet; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Male; Methionine; Mice; S-Adenosylhomocysteine; Vitamin B 12; Vitamin B 6 | 2008 |
Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study.
Topics: Adult; Betaine; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methionine; Parturition; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, Third; Seychelles; Vitamin B 12; Vitamin B Complex | 2008 |
Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer.
Topics: Adaptor Proteins, Signal Transducing; Aged; Cohort Studies; Colorectal Neoplasms; Diet; DNA Methylation; DNA, Neoplasm; Female; Folic Acid; Humans; Male; Methionine; Microsatellite Repeats; Middle Aged; Mutation; MutL Protein Homolog 1; Netherlands; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Riboflavin; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2008 |
Psychosis, paraplegia and coma revealing methylenetetrahydrofolate reductase deficiency in a 56-year-old woman.
Topics: Brain; Brain Diseases, Metabolic, Inborn; Catatonia; Chromosome Aberrations; Chromosomes, Human, Pair 1; Coma; Dementia; Exons; Folic Acid; Genes, Recessive; Homocysteine; Humans; Magnetic Resonance Imaging; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Neurologic Examination; Paraplegia; Polymorphism, Genetic; Psychotic Disorders | 2008 |
Cardiac autonomic dysfunction: effects from particulate air pollution and protection by dietary methyl nutrients and metabolic polymorphisms.
Topics: Aged; Aged, 80 and over; Boston; Cardiotonic Agents; Case-Control Studies; Diet; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Glycine Hydroxymethyltransferase; Heart Conduction System; Heart Rate; Humans; Male; Meteorological Concepts; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Particulate Matter; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B Complex | 2008 |
Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Sensitivity and Specificity | 2008 |
Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Ethanol; Fatty Liver; Fatty Liver, Alcoholic; Folic Acid; Gene Expression; Homocysteine; Humans; Methionine; Mice; Mice, Transgenic; Recombinant Proteins | 2008 |
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents | 2008 |
Methionine, folic acid and vitamin B12 in growing-finishing pigs: impact on growth performance and meat quality.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Body Composition; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Male; Meat; Methionine; Nutritional Requirements; Random Allocation; Swine; Vitamin B 12; Vitamin B Complex; Weight Gain | 2008 |
Folate and vitamin B6 intake and risk of colon cancer in relation to p53 expression.
Topics: Alcohol Drinking; Colonic Neoplasms; Diet; Female; Folic Acid; Folic Acid Deficiency; Genes, p53; Humans; Immunohistochemistry; Methionine; Middle Aged; Oligonucleotide Array Sequence Analysis; Risk Factors; Tumor Suppressor Protein p53; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2008 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |
Folate deprivation, the methionine cycle, and Alzheimer's disease.
Topics: Alzheimer Disease; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Methionine | 2008 |
Hypospadias and intake of nutrients related to one-carbon metabolism.
Topics: Carbon; Choline; Diet; Dietary Supplements; Female; Folic Acid; Humans; Hypospadias; Infant, Newborn; Male; Methionine; Pregnancy; Prenatal Nutritional Physiological Phenomena; Riboflavin; Thiamine; Vitamin B 12; Vitamin B 6; Zinc | 2009 |
Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer.
Topics: Aged; Cohort Studies; Colorectal Neoplasms; Diet; Diet Surveys; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Netherlands; Prospective Studies; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B 6 | 2008 |
Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation.
Topics: Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Folic Acid; Glucose; Homocysteine; Humans; Insulin; Methionine; Methylation; S-Adenosylmethionine; Sulfur | 2009 |
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Topics: Blotting, Western; Breast Neoplasms; Colonic Neoplasms; CpG Islands; DNA Damage; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Risk Factors; Tumor Cells, Cultured; Uracil | 2009 |
Tissue methionine cycle activity and homocysteine metabolism in female rats: impact of dietary methionine and folate plus choline.
Topics: Animals; Body Composition; Choline; Diet; Dietary Proteins; Female; Folic Acid; Homocysteine; Methionine; Models, Biological; Rats; Tissue Distribution | 2009 |
Effects of supplements of folic acid, vitamin B12, and rumen-protected methionine on whole body metabolism of methionine and glucose in lactating dairy cows.
Topics: Animals; Body Weight; Cattle; Dairying; Dietary Supplements; Female; Folic Acid; Glucose; Injections, Intramuscular; Lactation; Methionine; Pregnancy; Rumen; Vitamin B 12 | 2009 |
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice.
Topics: Animals; Cystathionine beta-Synthase; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Membrane Transport Proteins; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Knockout | 2009 |
Dietary B vitamin and methionine intakes and plasma folate are not associated with colorectal cancer risk in Chinese women.
Topics: Adult; Aged; Case-Control Studies; China; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Logistic Models; Methionine; Middle Aged; Niacinamide; Proportional Hazards Models; Prospective Studies; Registries; Riboflavin; Risk; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2009 |
Methionine-induced hyperhomocysteinemia modulates lipoprotein profile and oxidative stress but not progression of atherosclerosis in aged apolipoprotein E knockout mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Apolipoproteins E; Aspartate Aminotransferases; Atherosclerosis; Cholesterol; Folic Acid; Glutathione; Hyperhomocysteinemia; Lipoproteins; Male; Methionine; Mice; Mice, Knockout; NF-kappa B; Oxidative Stress; RNA, Messenger | 2009 |
Influence of methionine supply on the response of lactational performance of dairy cows to supplementary folic acid and vitamin B12.
Topics: Amino Acids; Animals; Blood Chemical Analysis; Cattle; Dairying; Diet; Female; Folic Acid; Injections, Intramuscular; Lactation; Methionine; Random Allocation; Vitamin B 12; Vitamin B Complex | 2009 |
Metabolism of methionine in vivo: impact of pregnancy, protein restriction, and fatty liver disease.
Topics: Animals; Diet, Protein-Restricted; Disease Models, Animal; Fatty Liver; Female; Fetal Growth Retardation; Folic Acid; Humans; Insulin Resistance; Methionine; Models, Animal; Pregnancy | 2009 |
Intake of folate, vitamins B6, B12 and methionine and risk of pancreatic cancer in a large population-based case-control study.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Case-Control Studies; Diet Surveys; Eating; Female; Folic Acid; Humans; Male; Methionine; Micronutrients; Middle Aged; Pancreatic Neoplasms; Population; Risk Factors; Vitamin B 12; Vitamin B 6; Young Adult | 2009 |
[Methyl-containing diet of mothers affects the AGOUTI gene expression in the offspring of rats with various behavioral types].
Topics: Aggression; Agouti Signaling Protein; Animals; Behavior, Animal; Betaine; Choline; Dietary Supplements; Female; Folic Acid; Hair Color; Methionine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Selection, Genetic; Species Specificity; Vitamin B 12; Zinc | 2009 |
Relationship between dietary and supplemental intake of folate, methionine, vitamin B6 and folate receptor alpha expression in ovarian tumors.
Topics: Adult; Carrier Proteins; Dietary Supplements; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Methionine; Middle Aged; Ovarian Neoplasms; Receptors, Cell Surface; Vitamin B 6 | 2010 |
One-carbon metabolism-genome interactions in folate-associated pathologies.
Topics: Animals; Carbon; Child; Developmental Disabilities; Disease Models, Animal; Environment; Folic Acid; Gastrointestinal Neoplasms; Genetic Phenomena; Genome, Human; Homocysteine; Humans; Methionine; Mice; Neural Tube Defects; Purines; Risk Factors; Thymidine Monophosphate | 2009 |
Folic acid, vitamin B12, and homocysteine levels during fasting and after methionine load in patients with Type 1 diabetes mellitus.
Topics: Adolescent; Adult; Aging; Blood Glucose; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Sex Characteristics; Vitamin B 12; Young Adult | 2010 |
Supplementation of a maternal low-protein diet in rat pregnancy with folic acid ameliorates programming effects upon feeding behaviour in the absence of disturbances to the methionine-homocysteine cycle.
Topics: Animals; Appetite Regulation; Caseins; Diet, Protein-Restricted; Dietary Fats; Dietary Supplements; DNA Methylation; Enzymes; Female; Folic Acid; Food Preferences; Glutathione; Homocysteine; Male; Methionine; Placentation; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Rats; Rats, Wistar; RNA, Messenger; Vitamin B Complex | 2010 |
MTHFR C677T and postmenopausal breast cancer risk by intakes of one-carbon metabolism nutrients: a nested case-control study.
Topics: Aged; Breast Neoplasms; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Postmenopause; Risk Factors; Vitamin B Complex | 2009 |
Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aging; Autoimmune Diseases; CD27 Ligand; CD28 Antigens; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Modification Methylases; Female; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Male; Methionine; Micronutrients; Middle Aged; Receptors, KIR; T-Lymphocytes | 2010 |
Chronic pancreatitis is associated with hyperhomocysteinemia and derangements in transsulfuration and transmethylation pathways.
Topics: Adult; Creatinine; Cysteine; Erythrocytes; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Middle Aged; Models, Biological; Multivariate Analysis; Pancreatitis, Alcoholic; Pancreatitis, Chronic; Regression Analysis; Signal Transduction; Sulfates; Sulfur; Young Adult | 2010 |
Endogenous folates and single-carbon metabolism in the ovarian follicle, oocyte and pre-implantation embryo.
Topics: Animals; Blastocyst; Carbohydrate Metabolism; Carbon; Cattle; Cells, Cultured; Female; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Enzymologic; Metabolic Networks and Pathways; Methionine; Methotrexate; Models, Biological; Oocytes; Ovarian Follicle; Sheep | 2010 |
Moderate or supranormal folic acid supplementation does not exert a protective effect for homocysteinemia and methylation markers in growing rats.
Topics: Analysis of Variance; Animals; Biomarkers; Chromatography, High Pressure Liquid; Diet; Dietary Supplements; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Glutathione; Homocysteine; Male; Methionine; Rats; Rats, Sprague-Dawley; Vitamin B Complex | 2010 |
CpG methylation of a silent controlling element in the murine Avy allele is incomplete and unresponsive to methyl donor supplementation.
Topics: Agouti Signaling Protein; Alleles; Animals; Base Sequence; Betaine; Choline; CpG Islands; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Genes, Intracisternal A-Particle; Germ Cells; Male; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Insertional; Phenotype; Promoter Regions, Genetic; Retroelements | 2010 |
Fasting and post-methionine homocysteine levels in Alzheimers disease and vascular dementia.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cohort Studies; Dementia, Vascular; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Statistics, Nonparametric; Vitamin B 12 | 2009 |
Folate bioavailability: implications for establishing dietary recommendations and optimizing status.
Topics: Adolescent; Adult; Biological Availability; Dietary Supplements; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Intestinal Absorption; Methionine; Middle Aged; Nutrition Policy; Nutritional Requirements; Premenopause; Young Adult | 2010 |
Are dietary choline and betaine intakes determinants of total homocysteine concentration?
Topics: Betaine; Cardiovascular Diseases; Choline; Cognition Disorders; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Vitamin B 12; Vitamin B 6 | 2010 |
Genetic variants of folate and methionine metabolism and PCNSL incidence in a German patient population.
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Germany; Humans; Incidence; Lymphoma; Male; Methionine; Middle Aged; Polymorphism, Single Nucleotide; White People | 2010 |
Effects of low methyl donor levels in culture medium during mouse follicle culture on oocyte imprinting establishment.
Topics: Analysis of Variance; Animals; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Culture Media; DNA Methylation; Female; Folic Acid; Genomic Imprinting; Methionine; Mice; Oocytes; Ovarian Follicle; Radioimmunoassay; Receptor, IGF Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Long Noncoding; RNA, Untranslated; snRNP Core Proteins; Vitamin B 12; Vitamin B 6 | 2010 |
Folate and other one-carbon metabolism-related nutrients and risk of postmenopausal breast cancer in the Cancer Prevention Study II Nutrition Cohort.
Topics: Aged; Alcohol Drinking; Breast Neoplasms; Cohort Studies; Female; Folic Acid; Humans; Methionine; Middle Aged; Postmenopause; Proportional Hazards Models; Prospective Studies; Surveys and Questionnaires; United States; Vitamin B 12; Vitamin B 6 | 2010 |
Effects of supplementary folic acid and vitamin B(12) on hepatic metabolism of dairy cows according to methionine supply.
Topics: Dairying; Diet; Dietary Supplements; Folic Acid; Gene Expression Regulation; Injections, Intramuscular; Lipid A; Liver; Methionine; Random Allocation; Time Factors; Vitamin B 12 | 2010 |
The importance of being choline.
Topics: Brain; Choline; Choline Deficiency; Folic Acid; Humans; Lipotropic Agents; Liver; Methionine; Nootropic Agents; Nutrition Policy; Nutritional Requirements | 2010 |
Evaluation of mild hyperhomocysteinemia during the development of atherosclerosis in apolipoprotein E-deficient and normal mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Diet; Endoplasmic Reticulum; Folic Acid; Hyperhomocysteinemia; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Time Factors | 2011 |
The reliability of methionine challenge test is not affected by a deficiency in pyridoxal phosphate, folic acid, or cobalamin.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Methionine; Pregnancy; Pyridoxal Phosphate; Reproducibility of Results; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2011 |
Functional interactions between the LRP6 WNT co-receptor and folate supplementation.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Folic Acid; Gene Expression; Gene Expression Regulation, Developmental; Immunohistochemistry; LDL-Receptor Related Proteins; Low Density Lipoprotein Receptor-Related Protein-6; Methionine; Mice; Mice, Inbred C3H; Mitochondria; Mutation; Neural Crest; Neural Tube Defects; NIH 3T3 Cells; Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Signal Transduction; Wnt Proteins | 2010 |
Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer.
Topics: Aged; Colorectal Neoplasms; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Methyltransferases; Middle Aged; Polymerase Chain Reaction; Promoter Regions, Genetic; Vitamin B 6 | 2011 |
Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney.
Topics: Acetophenones; Animals; Cells, Cultured; Folic Acid; Humans; Hyperhomocysteinemia; Kidney; Male; Methionine; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 2011 |
Endothelial microparticle formation in moderate concentrations of homocysteine and methionine in vitro.
Topics: Apoptosis; Cell-Derived Microparticles; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; Folic Acid; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Umbilical Cord | 2011 |
High intake of folate from food sources is associated with reduced risk of esophageal cancer in an Australian population.
Topics: Adenocarcinoma; Adult; Aged; Alcohol Drinking; Australia; Barrett Esophagus; Betaine; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Dietary Supplements; Esophageal Neoplasms; Esophagus; Female; Folic Acid; Humans; Logistic Models; Male; Methionine; Middle Aged; Risk Factors; Smoking; Vitamin B Complex | 2011 |
Dietary and supplemental intake of one-carbon nutrients and the risk of type I and type II endometrial cancer: a prospective cohort study.
Topics: Aged; Chromosomal Instability; Cohort Studies; Diet; Dietary Supplements; DNA Methylation; Endometrial Neoplasms; Female; Folic Acid; Humans; Methionine; Middle Aged; Minnesota; Prospective Studies; Vitamins | 2011 |
Congenital heart defects and maternal genetic, metabolic, and lifestyle factors.
Topics: Adult; Arkansas; Biomarkers; Case-Control Studies; Female; Folic Acid; Genetic Variation; Genotype; Glutathione Disulfide; Heart Defects, Congenital; Humans; Life Style; Linear Models; Logistic Models; Methionine; Multivariate Analysis; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors | 2011 |
A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition.
Topics: Adult; Aged; Alcohol Drinking; Body Mass Index; Case-Control Studies; Cotinine; Diabetes Complications; DNA-Binding Proteins; Europe; Female; Flavin Mononucleotide; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Prospective Studies; Pyridoxal Phosphate; Riboflavin; Risk Factors; Sex Factors; Smoking; Transcription Factors; Vitamin B 12; Vitamin B Complex | 2011 |
Dietary B vitamin and methionine intakes and breast cancer risk among Chinese women.
Topics: Adult; Age Factors; Aged; Breast Neoplasms; Chi-Square Distribution; China; Diet; Female; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Middle Aged; Nutrition Surveys; Proportional Hazards Models; Prospective Studies; Risk Factors | 2011 |
Nutrients in folate-mediated, one-carbon metabolism and the risk of rectal tumors in men and women.
Topics: Adult; Aged; Case-Control Studies; CpG Islands; Diet; Dietary Supplements; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Logistic Models; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Phenotype; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rectal Neoplasms; Riboflavin; Risk Factors; Sex Factors; Tumor Suppressor Protein p53; Vitamin B 12; Vitamin B 6 | 2011 |
Folate is related to phosphorylated neurofilament-H and P-tau (Ser396) in rat brain.
Topics: Animals; Brain; Female; Folic Acid; Frontal Lobe; Homocysteine; Homocystine; Hyperhomocysteinemia; Methionine; Methylation; Neurofilament Proteins; Phosphoproteins; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; tau Proteins | 2011 |
Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Brazil; Colorectal Neoplasms; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Heterozygote; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Pilot Projects; Polymorphism, Single Nucleotide; Risk; Thymidylate Synthase | 2011 |
Dietary folate, vitamin B6, vitamin B12 and methionine intake and the risk of breast cancer by oestrogen and progesterone receptor status.
Topics: Adult; Age Factors; Aged; Breast Neoplasms; Case-Control Studies; China; Diet; Female; Folic Acid; Humans; Methionine; Middle Aged; Multivariate Analysis; Receptors, Estrogen; Receptors, Progesterone; Regression Analysis; Rural Population; Urban Population; Vitamin B 12; Vitamin B 6 | 2011 |
B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
Topics: Adaptor Proteins, Signal Transducing; Adult; Basic Helix-Loop-Helix Transcription Factors; Calcium Channels, T-Type; Cell Cycle Proteins; Colonic Neoplasms; Core Binding Factor Alpha 3 Subunit; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Female; Folic Acid; Humans; Insulin-Like Growth Factor II; Kruppel-Like Transcription Factors; Methionine; Middle Aged; Mutation; MutL Protein Homolog 1; Neoplasm Proteins; Nerve Tissue Proteins; Nuclear Proteins; Poly-ADP-Ribose Binding Proteins; Polymerase Chain Reaction; Proto-Oncogene Proteins B-raf; Receptors, Retinoic Acid; Risk Factors; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Surveys and Questionnaires; Ubiquitin-Protein Ligases | 2011 |
Nutrients and genetic variation involved in one-carbon metabolism and Hodgkin lymphoma risk: a population-based case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Aged; Boston; Carbon; Case-Control Studies; Connecticut; DNA Primers; Female; Folic Acid; Food; Genotype; Herpesvirus 4, Human; Hodgkin Disease; Humans; Logistic Models; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Surveys and Questionnaires; Thymidylate Synthase; Vitamin B Complex; Vitamins; Young Adult | 2011 |
Dietary methyl-consuming compounds and metabolic syndrome.
Topics: Animals; Arsenicals; Catecholamines; Diet; Folic Acid; Homocysteine; Humans; Hypolipidemic Agents; Insulin Resistance; Metabolic Syndrome; Methionine; Niacin; Reactive Oxygen Species | 2011 |
Homocysteine homeostasis in the rat is maintained by compensatory changes in cystathionine β-synthase, betaine-homocysteine methyltransferase, and phosphatidylethanolamine N-methyltransferase gene transcription occurring in response to maternal protein an
Topics: Animal Nutritional Physiological Phenomena; Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Diet; Diet, High-Fat; Diet, Protein-Restricted; Dietary Fats; Dietary Proteins; Dietary Supplements; Down-Regulation; Female; Folic Acid; Gene Expression; Homeostasis; Homocysteine; Liver; Male; Methionine; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Pregnancy; Prenatal Nutritional Physiological Phenomena; Rats, Wistar; Vitamin B Complex; Weaning | 2011 |
Promoter methylation of E-cadherin, p16, and RAR-β(2) genes in breast tumors and dietary intake of nutrients important in one-carbon metabolism.
Topics: Adult; Aged; Breast Neoplasms; Cadherins; Case-Control Studies; Cyclin-Dependent Kinase Inhibitor p16; Diet; DNA Methylation; Female; Folic Acid; Humans; Logistic Models; Methionine; Middle Aged; New York; Odds Ratio; Promoter Regions, Genetic; Receptors, Retinoic Acid; Surveys and Questionnaires; Vitamin B Complex | 2011 |
Folate, vitamin B(6) , vitamin B(12) , methionine and alcohol intake in relation to ovarian cancer risk.
Topics: Adult; Alcohol Drinking; Case-Control Studies; Female; Folic Acid; Humans; Methionine; Ovarian Neoplasms; Risk Factors; Vitamin B 12; Vitamin B 6 | 2012 |
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6 | 2012 |
Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo.
Topics: Animals; Antirheumatic Agents; Dactinomycin; Dexamethasone; Enzyme Inhibitors; Folic Acid; Gene Expression Regulation; Hep G2 Cells; Humans; Male; Methionine; Methionine Adenosyltransferase; Methotrexate; Mice; Mice, Inbred C57BL; RNA, Messenger; S-Adenosylmethionine | 2012 |
Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.
Topics: Adult; Animals; Asian People; Black People; Catechol O-Methyltransferase; Chlorocebus aethiops; COS Cells; Female; Folic Acid; Gene Expression; Genetic Variation; Genome; Genomics; Genotype; Glycine Hydroxymethyltransferase; Glycine N-Methyltransferase; Humans; Linkage Disequilibrium; Liver; Lymphocytes; Male; Methionine; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide; RNA, Messenger; Sequence Analysis, DNA; Statistics as Topic; Transfection; White People | 2012 |
Altered placental methyl donor transport in the dexamethasone programmed rat.
Topics: Animals; Biological Transport; Choline; Dexamethasone; DNA Methylation; Embryonic Development; Epistasis, Genetic; Female; Folic Acid; Methane; Methionine; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 2012 |
Post-translational stabilization of thiopurine S-methyltransferase by S-adenosyl-L-methionine reveals regulation of TPMT*1 and *3C allozymes.
Topics: Cell Culture Techniques; Culture Media; Enzyme Inhibitors; Erythrocytes; Folic Acid; Genotype; HEK293 Cells; Hep G2 Cells; Humans; Isoenzymes; Methionine; Methionine Adenosyltransferase; Methyltransferases; Protein Processing, Post-Translational; Protein Stability; S-Adenosylmethionine | 2012 |
Effects of methyl-deficient diets on methionine and homocysteine metabolism in the pregnant rat.
Topics: Animals; Choline; Cysteine; Diet; Female; Fetus; Folic Acid; Homocysteine; Kinetics; Litter Size; Liver; Methionine; Methylation; Pancreas; Phosphorylcholine; Placenta; Pregnancy; Rats; Triglycerides; Weight Gain | 2012 |
Salutary effect of NFκB inhibitor and folacin in hyperhomocysteinemia-hyperlipidemia induced vascular dementia.
Topics: Acetylcholinesterase; Animals; Dementia, Vascular; Ditiocarb; Endothelium, Vascular; Folic Acid; Hyperhomocysteinemia; Hyperlipidemias; Male; Maze Learning; Methionine; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar | 2012 |
Dietary intake of B vitamins and methionine and prostate cancer incidence and mortality.
Topics: Adult; Aged; Aged, 80 and over; Australia; Cohort Studies; Confidence Intervals; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Methionine; Middle Aged; Proportional Hazards Models; Prospective Studies; Prostatic Neoplasms; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B Complex | 2012 |
Maternal intake of methyl-donor nutrients and child cognition at 3 years of age.
Topics: Adult; Betaine; Child Development; Child, Preschool; Choline; Cognition; Cohort Studies; Diet; DNA Methylation; Female; Folic Acid; Food; Humans; Massachusetts; Maternal Age; Maternal Nutritional Physiological Phenomena; Methionine; Multivariate Analysis; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Prospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2012 |
Associations between toenail arsenic concentration and dietary factors in a New Hampshire population.
Topics: Aged; Arsenic; Case-Control Studies; Diet; Dietary Fats; Docosahexaenoic Acids; Drinking Water; Eicosapentaenoic Acid; Environmental Exposure; Female; Fish Oils; Folic Acid; Humans; Male; Methionine; Middle Aged; Nails; New Hampshire; Regression Analysis; Surveys and Questionnaires; Urinary Bladder Neoplasms; Vitamin B 12; Water Wells | 2012 |
Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C→T polymorphism.
Topics: Biomarkers; Cardiovascular Diseases; Comorbidity; Cross-Sectional Studies; Diabetes Mellitus; Dinoprost; Dyslipidemias; Folic Acid; Homocystinuria; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Oxidative Stress; Platelet Activation; Polymorphism, Single Nucleotide; Psychotic Disorders; Smoking; Thromboxane B2 | 2012 |
A candidate gene study of one-carbon metabolism pathway genes and colorectal cancer risk.
Topics: Aged; Carbon; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Mutagenesis, Insertional; Nucleotides; One-Carbon Group Transferases; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12 | 2013 |
Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation.
Topics: Asian People; Biopsy; Black or African American; Blotting, Western; Folic Acid; Gene Expression Regulation, Enzymologic; Genes, Reporter; Genetic Association Studies; Genomics; Genotype; Glycine N-Methyltransferase; HEK293 Cells; Hep G2 Cells; Humans; Liver; Methionine; Methionine Adenosyltransferase; Phenotype; Polymorphism, Single Nucleotide; S-Adenosylmethionine; Sequence Analysis, DNA; Transfection; White People | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Gene-diet-interactions in folate-mediated one-carbon metabolism modify colon cancer risk.
Topics: Adult; Aged; Case-Control Studies; Colonic Neoplasms; Diet; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine Hydroxymethyltransferase; Humans; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Minor Histocompatibility Antigens; Polymorphism, Genetic; Riboflavin; Risk Factors; Vitamin B 12; Vitamin B 6 | 2013 |
Folic acid fortification ameliorates hyperhomocysteinemia caused by a vitamin B₆-deficient diet supplemented with L-methionine.
Topics: Animals; Body Weight; Dietary Supplements; Eating; Folic Acid; Hyperhomocysteinemia; Male; Methionine; Pilot Projects; Rats; Rats, Wistar; Vitamin B 6 Deficiency | 2012 |
Associations between maternal genotypes and metabolites implicated in congenital heart defects.
Topics: Adult; Asymptomatic Diseases; Carbon-Nitrogen Ligases; Case-Control Studies; Catalase; DNA (Cytosine-5-)-Methyltransferases; DNA Modification Methylases; DNA Repair Enzymes; Female; Folic Acid; Genotype; Glutathione; Glutathione Peroxidase; Heart Defects, Congenital; Homocysteine; Humans; Life Style; Male; Methionine; Methionine Adenosyltransferase; Polymorphism, Single Nucleotide; Risk; Tumor Suppressor Proteins | 2012 |
Plasma B vitamins and LINE-1 DNA methylation in leukocytes of patients with a history of colorectal adenomas.
Topics: Adenoma; Adolescent; Adult; Aged; Colorectal Neoplasms; Cross-Sectional Studies; DNA Methylation; Female; Folic Acid; Follow-Up Studies; Genotype; Humans; Leukocytes; Life Style; Linear Models; Long Interspersed Nucleotide Elements; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Risk Factors; Surveys and Questionnaires; Vitamin B Complex; Young Adult | 2013 |
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins | 2013 |
Palm tocotrienol-rich fraction reduced plasma homocysteine and heart oxidative stress in rats fed with a high-methionine diet.
Topics: Administration, Oral; Animals; Catalase; Cycas; Diet; Dietary Supplements; Folic Acid; Glutathione Peroxidase; Heart; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tocotrienols | 2013 |
Induction of hyperhomocysteinemia models vascular dementia by induction of cerebral microhemorrhages and neuroinflammation.
Topics: Animals; Brain; Cerebral Hemorrhage; Dementia, Vascular; Diet; Disease Models, Animal; Folic Acid; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Memory Disorders; Methionine; Mice; Mice, Inbred C57BL; Vitamin B 12; Vitamin B 6 | 2013 |
Dietary intake of folate, B-vitamins and methionine and breast cancer risk among Hispanic and non-Hispanic white women.
Topics: Breast Neoplasms; Female; Folic Acid; Hispanic or Latino; Humans; Methionine; Risk Factors; Vitamin B Complex; White People | 2013 |
[Association of serum homocysteine and methionine levels with cognition and functioning in bipolar disorder].
Topics: Bipolar Disorder; Case-Control Studies; Cognition; Folic Acid; Homocysteine; Humans; Methionine; Psychiatric Status Rating Scales; Severity of Illness Index; Vitamin B 12 | 2013 |
One-carbon metabolism factors and leukocyte telomere length.
Topics: Aged; Biomarkers; Carbon; Choline; Cross-Sectional Studies; Diet; DNA; DNA Methylation; Ethanol; Folic Acid; Genotype; Humans; Leukocytes; Metabolic Networks and Pathways; Methionine; Middle Aged; Multivariate Analysis; Nutritional Status; Polymorphism, Single Nucleotide; Surveys and Questionnaires; Telomere; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
A structural equation modelling approach to explore the role of B vitamins and immune markers in lung cancer risk.
Topics: Biomarkers; Folic Acid; Humans; Lung Neoplasms; Male; Methionine; Models, Statistical; Population Surveillance; Prospective Studies; Risk Factors; Vitamin B Complex | 2013 |
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Topics: Adenylate Kinase; Aging; Animals; Biguanides; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caloric Restriction; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Escherichia coli; Folic Acid; Humans; Hypoglycemic Agents; Longevity; Metagenome; Metformin; Methionine; Transcription Factors | 2013 |
Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus.
Topics: Animals; Antibodies, Antinuclear; Betaine; CD40 Ligand; Choline; Coenzymes; Diet; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Silencing; Genetic Predisposition to Disease; Lupus Erythematosus, Systemic; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronutrients; Riboflavin; Vitamin B 12; Vitamin B 6; Zinc | 2013 |
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult | 2013 |
A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
Topics: Aminohydrolases; Animals; Cell Proliferation; Cells, Cultured; Choline; Congenital Abnormalities; Embryo Loss; Embryonic Development; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Gene Knock-In Techniques; Genetic Variation; Humans; Leucovorin; Leukocyte Count; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Models, Animal; Multienzyme Complexes; Multifunctional Enzymes; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Purines | 2013 |
Metformin, microbes, and aging.
Topics: Animals; Caenorhabditis elegans; Folic Acid; Humans; Hypoglycemic Agents; Longevity; Metformin; Methionine | 2013 |
Early biochemical and hematological response to intramuscular cyanocobalamin therapy in vitamin B(12)-deficient patients.
Topics: Aged; Chromatography, High Pressure Liquid; Cysteine; Erythrocyte Indices; Female; Folic Acid; Homocysteine; Humans; Injections, Intramuscular; Male; Methionine; Methylmalonic Acid; Middle Aged; Statistics, Nonparametric; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
A population model of folate-mediated one-carbon metabolism.
Topics: Carbon; Diet; Folic Acid; Homocysteine; Humans; Liver; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Models, Theoretical; Nutrition Surveys; Oxidative Stress; Polymorphism, Genetic | 2013 |
Dietary intake of B vitamins and methionine and colorectal cancer risk.
Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Confidence Intervals; Diet; Female; Folic Acid; Follow-Up Studies; Humans; Male; Methionine; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
Nutritional control of epigenetic processes in yeast and human cells.
Topics: Epigenesis, Genetic; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Histones; Humans; Infant, Newborn; K562 Cells; Methionine; Methylation; Neural Tube Defects; Pregnancy; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Species Specificity | 2013 |
Associations of dietary folate, Vitamins B6 and B12 and methionine intake with risk of breast cancer among African American and European American women.
Topics: Adolescent; Adult; Black or African American; Breast Neoplasms; Case-Control Studies; Diet; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Methionine; Middle Aged; Neoplasm Staging; Premenopause; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamins; White People; Young Adult | 2014 |
Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants.
Topics: Adult; Betaine; British Columbia; Child Development; Choline; Dietary Supplements; Female; Folic Acid; Humans; Infant; Male; Methionine; Middle Aged; Pregnancy; Prospective Studies; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Nutri-epigenetics ameliorates blood-brain barrier damage and neurodegeneration in hyperhomocysteinemia: role of folic acid.
Topics: Adenosylhomocysteinase; Animals; Blood-Brain Barrier; Cystathionine beta-Synthase; Diet; Epigenesis, Genetic; Folic Acid; Heterozygote; Hyperhomocysteinemia; Matrix Metalloproteinases; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress | 2014 |
Effects of methyl donor diets on incisional pain in mice.
Topics: Animals; Choline; Dietary Supplements; Female; Folic Acid; Hindlimb; Hyperalgesia; Male; Methionine; Mice; Mice, Inbred C57BL; Pain; Vitamin B 12; Weaning | 2013 |
Pubertal supplementation of lipotropes in female rats reduces mammary cancer risk by suppressing histone deacetylase 1.
Topics: Animals; Breast Neoplasms; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Female; Folic Acid; Histone Deacetylase 1; Methionine; Methylnitrosourea; Micronutrients; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Vitamin B 12 | 2014 |
Intakes of folate, methionine, vitamin B6, and vitamin B12 with risk of esophageal and gastric cancer in a large cohort study.
Topics: Carcinoma, Squamous Cell; Cohort Studies; Diet; Esophageal Neoplasms; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Risk; Stomach Neoplasms; United States; Vitamin B 12; Vitamin B 6 | 2014 |
Structural analysis of a fungal methionine synthase with substrates and inhibitors.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Candida albicans; Catalytic Domain; Crystallography, X-Ray; Folic Acid; Fungal Proteins; Homocysteine; Kinetics; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Zinc | 2014 |
One-carbon metabolism dietary factors and distal gastric cancer risk in chinese women.
Topics: Adult; Aged; Asian People; Diet; Diet Surveys; Female; Folic Acid; Humans; Methionine; Middle Aged; Stomach Neoplasms; Vitamin B Complex | 2014 |
Validation of a food-frequency questionnaire assessment of methyl-group donors using estimated diet records and plasma biomarkers: the method of triads.
Topics: Adolescent; Adult; Belgium; Betaine; Biomarkers; Choline; Diet; Diet Records; Energy Intake; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Nutritional Status; Reproducibility of Results; S-Adenosylhomocysteine; S-Adenosylmethionine; Surveys and Questionnaires; Young Adult | 2014 |
Cheese 'refinement' with whey B-vitamin removal during precipitation potentially induces temporal 'functional' dietary shortage: homocysteine as a biomarker.
Topics: Adult; Biomarkers; Body Mass Index; Cheese; Diet; Dietary Supplements; Endpoint Determination; Female; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Israel; Methionine; Middle Aged; Vitamin B 6; Vitamin B Complex | 2014 |
Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Dihydropteroate Synthase; Drug Evaluation, Preclinical; Drug Synergism; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Bacterial; Humans; Methionine; Mycobacterium tuberculosis; S-Adenosylmethionine; Species Specificity; Tetrahydrofolate Dehydrogenase; Triazines | 2014 |
Dietary one-carbon nutrient intake and risk of lymphoid and myeloid neoplasms: results of the Netherlands cohort study.
Topics: Aged; Alcohol Drinking; Carbon; Cohort Studies; Diet; Female; Folic Acid; Food; Hematologic Neoplasms; Humans; Male; Methionine; Middle Aged; Netherlands; Proportional Hazards Models; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B 6 | 2014 |
Severe 5,10-methylenetetrahydrofolate reductase deficiency and two MTHFR variants in an adolescent with progressive myoclonic epilepsy.
Topics: Adolescent; Betaine; Female; Folic Acid; Homocystinuria; Humans; Lipotropic Agents; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Mutation; Myoclonic Epilepsies, Progressive; Psychotic Disorders; Vitamin B Complex | 2014 |
Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency.
Topics: Animals; Cell Cycle Checkpoints; Cell Line; Cell Nucleus; Coenzymes; Diet; DNA; Female; Folic Acid; Folic Acid Deficiency; Formates; Gene Knockdown Techniques; Glycine Hydroxymethyltransferase; Humans; Liver; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Protein Transport; Purines; S Phase; Thymidine Monophosphate; Uracil | 2014 |
Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny.
Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Epilepsy, Reflex; Female; Folic Acid; Male; Maternal Welfare; Methionine; Methylation; Pregnancy; Rats; Rats, Wistar; Vitamin B 12 | 2014 |
Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism.
Topics: Animals; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Catalase; Chromatography, High Pressure Liquid; Cochlea; Female; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Glutathione Synthase; Hair Cells, Auditory; Hearing Loss; Homocysteine; Hyperhomocysteinemia; In Situ Nick-End Labeling; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase | 2015 |
Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region.
Topics: Adult; Aged; Alcohol Drinking; Colorectal Neoplasms; DNA Methylation; Energy Intake; Epigenesis, Genetic; Ethanol; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Insulin-Like Growth Factor II; Male; Methionine; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2014 |
In vivo kinetics of formate metabolism in folate-deficient and folate-replete rats.
Topics: Animals; Choline; Dimethylglycine Dehydrogenase; Folic Acid; Folic Acid Deficiency; Formaldehyde; Formates; Glycine; Histidine; Liver; Male; Methionine; Mitochondria; Mitochondria, Liver; Oxygen; Rats; Rats, Sprague-Dawley; Sarcosine Dehydrogenase; Serine; Tetrahydrofolates | 2015 |
Heterozygous carriers of classical homocystinuria tend to have higher fasting serum homocysteine concentrations than non-carriers in the presence of folate deficiency.
Topics: Aged; Cardiovascular Diseases; Case-Control Studies; Cystathionine beta-Synthase; Dietary Supplements; Fasting; Female; Folic Acid; Folic Acid Deficiency; Genotyping Techniques; Heterozygote; Homocysteine; Homocystinuria; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prevalence; Risk Factors; Taiwan; Vitamin B 12 | 2015 |
Reproducibility and validity of an FFQ to assess usual intake of methyl-group donors.
Topics: Adolescent; Adult; Belgium; Betaine; Choline; Diet; Diet Surveys; Feeding Behavior; Female; Folic Acid; Humans; Methionine; Methylation; Nutrition Assessment; Reproducibility of Results; Surveys and Questionnaires; Young Adult | 2015 |
Methyl-donor deficiency in adolescence affects memory and epigenetic status in the mouse hippocampus.
Topics: Age Factors; Animals; Choline; Choline Deficiency; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Hippocampus; Homocysteine; Memory; Methionine; Mice; Mice, Inbred C57BL; Models, Animal; Nutritional Requirements; Promoter Regions, Genetic; Receptors, AMPA; Receptors, Glutamate | 2015 |
Serine hydroxymethyltransferase: a key player connecting purine, folate and methionine metabolism in Saccharomyces cerevisiae.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aminoimidazole Carboxamide; Carbon-Nitrogen Ligases; Folic Acid; Gene Expression Regulation, Fungal; Glycine Hydroxymethyltransferase; Histidine; Leucovorin; Methionine; Mutation; Purines; Ribonucleotides; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tetrahydrofolates; Thymidine; Trans-Activators; Transcriptional Activation | 2015 |
Clinical pattern, mutations and in vitro residual activity in 33 patients with severe 5, 10 methylenetetrahydrofolate reductase (MTHFR) deficiency.
Topics: Ataxia; Betaine; Child; Female; Folic Acid; Genetic Association Studies; Homocystinuria; Humans; Intellectual Disability; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Mutation; Phenotype; Psychotic Disorders; Retrospective Studies; Spinal Cord Diseases; Vitamin B 12 | 2016 |
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6 | 2015 |
Methylating micronutrient supplementation during pregnancy influences foetal hepatic gene expression and IGF signalling and increases foetal weight.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Choline; Diet; Dietary Supplements; Female; Fetal Development; Fetal Weight; Fetus; Folic Acid; Gene Expression; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor II; Liver; Maternal Nutritional Physiological Phenomena; Methionine; Micronutrients; Muscle, Skeletal; Pregnancy; Signal Transduction; Swine; Vitamin B 12; Vitamin B 6 | 2016 |
Dietary folic acid protects against genotoxicity in the red blood cells of mice.
Topics: Animals; Dietary Supplements; DNA Damage; Erythrocytes; Folic Acid; Folic Acid Deficiency; Methionine; Mice; Reticulocytes | 2015 |
Accurate measurement of the essential micronutrients methionine, homocysteine, vitamins B6, B12, B9 and their metabolites in plasma, brain and maternal milk of mice using LC/MS ion trap analysis.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Male; Mass Spectrometry; Methionine; Mice; Mice, Inbred C57BL; Micronutrients; Milk; Vitamin B 12; Vitamin B 6 | 2015 |
Dietary Intakes of Folic Acid and Methionine in Early Childhood Are Associated with Body Composition at School Age.
Topics: Absorptiometry, Photon; Adiposity; Body Composition; Body Mass Index; Body Weight; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Female; Folic Acid; Humans; Infant; Male; Methionine; Netherlands; Nutrition Assessment; Prospective Studies; Reproducibility of Results; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; White People | 2015 |
Effect of multi-nutrient insufficiency on markers of one carbon metabolism in young women: response to a methionine load.
Topics: Adult; Amino Acids; Biomarkers; Body Height; Carbon; Female; Folic Acid; Food; Glutathione; Homocysteine; Humans; India; Malnutrition; Methionine; Ohio; Vitamin B 12; Vitamin B Complex | 2016 |
Betaine is as effective as folate at re-synthesizing methionine for protein synthesis during moderate methionine deficiency in piglets.
Topics: Animals; Betaine; Carbon Isotopes; Choline; Cysteine; Diet; Dietary Supplements; Folic Acid; Homocysteine; Methionine; Models, Biological; Oxidation-Reduction; Phenylalanine; Protein Biosynthesis; Swine | 2016 |
Suppression of Mammary Carcinogenesis Through Early Exposure to Dietary Lipotropes Occurs Primarily In Utero.
Topics: Animals; Animals, Newborn; Choline; Chromatin Assembly and Disassembly; Diet; Female; Folic Acid; Histone Deacetylases; Lactation; Mammary Neoplasms, Animal; Maternal-Fetal Exchange; Methionine; Methylnitrosourea; Pregnancy; Rats; Rats, Sprague-Dawley; Vitamin B 12 | 2015 |
Folate, vitamin B6, vitamin B12 and methionine intakes and risk for nasopharyngeal carcinoma in Chinese adults: a matched case-control study.
Topics: Adult; Carcinoma; Case-Control Studies; China; Diet; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Nasopharynx; Odds Ratio; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2016 |
Association study of the common polymorphisms in the folate-methionine pathway with retinoblastoma.
Topics: Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotyping Techniques; Humans; Iran; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Retinal Neoplasms; Retinoblastoma; Risk Factors; Tandem Repeat Sequences; Thymidylate Synthase | 2016 |
MTHFD1 controls DNA methylation in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Cytoplasm; DNA Demethylation; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Expression Regulation, Plant; Gene Silencing; Green Fluorescent Proteins; Histones; Homeostasis; Lysine; Methenyltetrahydrofolate Cyclohydrolase; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Models, Biological; Mutation; Protein Transport; S-Adenosylmethionine; Tetrahydrofolates | 2016 |
Maternal prenatal intake of one-carbon metabolism nutrients and risk of childhood leukemia.
Topics: Adolescent; Adult; California; Carbon; Case-Control Studies; Child; Child, Preschool; Dietary Supplements; Energy Intake; Female; Folic Acid; Hispanic or Latino; Humans; Infant; Infant, Newborn; Logistic Models; Male; Maternal Health; Methionine; Odds Ratio; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Prenatal Care; Riboflavin; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats.
Topics: Aneurysm, Ruptured; Animals; Arteries; Blood Pressure; Cysteine; Cytokines; Disease Models, Animal; Female; Folic Acid; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Methionine; NADPH Oxidase 4; NADPH Oxidases; Ovariectomy; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Vitamin B Complex | 2016 |
Components of One-carbon Metabolism Other than Folate and Colorectal Cancer Risk.
Topics: Aged; Amino Acids; Betaine; Biomarkers; Biomarkers, Tumor; Case-Control Studies; Choline; Colorectal Neoplasms; Female; Folic Acid; Follow-Up Studies; Humans; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Prospective Studies; Protective Factors; Sarcosine; Sweden | 2016 |
Methionine restriction inhibits chemically-induced malignant transformation in the BALB/c 3T3 cell transformation assay.
Topics: Animals; BALB 3T3 Cells; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; Folic Acid; Methionine; Methylcholanthrene; Mice; Vitamin B Complex | 2016 |
Maternal Methyl-Group Donor Intake and Global DNA (Hydroxy)Methylation before and during Pregnancy.
Topics: 5-Methylcytosine; Adult; Belgium; Betaine; Biomarkers; Choline; Cohort Studies; Cytosine; Diet; Dietary Supplements; DNA Methylation; Feeding Behavior; Female; Folic Acid; Humans; Hydroxylation; Leukocytes; Longitudinal Studies; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Prospective Studies; Self Report | 2016 |
Methyl Donor Status Influences DNMT Expression and Global DNA Methylation in Cervical Cancer Cells.
Topics: Blotting, Western; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Folic Acid; Humans; Methionine; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2016 |
Dietary Methyl Donor Depletion Suppresses Intestinal Adenoma Development.
Topics: Adenoma; Animals; Choline; Diet; Folic Acid; Intestinal Neoplasms; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Random Allocation; Vitamin B 12 | 2016 |
Dietary methyl donors affect in vivo methionine partitioning between transmethylation and protein synthesis in the neonatal piglet.
Topics: Animals; Betaine; Choline; Cysteine; Diet; Feeding Behavior; Folic Acid; Methionine; Methylation; Protein Biosynthesis; Swine | 2016 |
Dietary Methyl Donors Contribute to Whole-Body Protein Turnover and Protein Synthesis in Skeletal Muscle and the Jejunum in Neonatal Piglets.
Topics: Animals; Animals, Newborn; Betaine; Choline; Diet; Dose-Response Relationship, Drug; Female; Folic Acid; Jejunum; Male; Methionine; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Swine | 2016 |
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study.
Topics: Adipose Tissue; Adolescent; Adult; Betaine; Birth Weight; Body Composition; Body Mass Index; Choline; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Infant; Linear Models; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Singapore; Vitamin B 12; Young Adult | 2016 |
Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs.
Topics: Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Folic Acid; Homocysteine; Methionine; Microbial Sensitivity Tests; Vitamin B 12 | 2016 |
Dietary and supplemental maternal methyl-group donor intake and cord blood DNA methylation.
Topics: Adult; Betaine; Choline; Cohort Studies; Diet; Dietary Supplements; DNA Methylation; Epigenomics; Feeding Behavior; Female; Fetal Blood; Folic Acid; Humans; Maternal Nutritional Physiological Phenomena; Methionine; Nutrition Surveys; Pregnancy; Surveys and Questionnaires | 2017 |
Elucidation of roles for vitamin B
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Biochemical Phenomena; Folic Acid; Gammaproteobacteria; Halomonas; Methionine; Protein Binding; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Ubiquinone; Ultraviolet Rays; Vitamin B 12 | 2017 |
The effect of paternal methyl-group donor intake on offspring DNA methylation and birth weight.
Topics: Adult; Belgium; Betaine; Birth Weight; Choline; DNA Methylation; Female; Fetal Blood; Folic Acid; Humans; Male; Methionine; Middle Aged; Obesity | 2017 |
Antioxidant effect of thiazolidine molecules in cell culture media improves stability and performance.
Topics: Animals; Antioxidants; CHO Cells; Cricetulus; Culture Media; Folic Acid; Methionine; Superoxide Dismutase; Thiamine; Thiazolidines; Tryptophan | 2017 |
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.
Topics: Animals; Cognition; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Fathers; Folic Acid; Hippocampus; Large-Conductance Calcium-Activated Potassium Channel beta Subunits; Learning; Male; Memory; Methionine; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred C57BL; Neurons; Paternal Inheritance; Promoter Regions, Genetic | 2018 |
A paternal diet for offspring success?
Topics: Animals; Dietary Supplements; Feeding Behavior; Folic Acid; Male; Methionine; Mice; Paternal Exposure | 2017 |
[Effect of peripheral bloodgenomic DNA methylation on the relationship between methyl donor status and risk of breast cancer].
Topics: Betaine; Breast Neoplasms; Case-Control Studies; Choline; Colonic Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Humans; Methionine; Nutrition Surveys; Risk | 2017 |
Maternal Exposure to Nitrogen Dioxide, Intake of Methyl Nutrients, and Congenital Heart Defects in Offspring.
Topics: Adult; Air Pollutants; Air Pollution; Case-Control Studies; Choline; Diet Records; Eating; Female; Folic Acid; Food Analysis; Heart Defects, Congenital; Humans; Infant, Newborn; Maternal Exposure; Methionine; Nitrogen Dioxide; Odds Ratio; Pregnancy; Prenatal Nutritional Physiological Phenomena; Risk Factors; United States; Vitamin B 12; Vitamin B 6 | 2017 |
The role of the Met
Topics: Amino Acid Substitution; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Databases, Protein; Energy Transfer; Escherichia coli; Escherichia coli Proteins; Folic Acid; Kinetics; Ligands; Methionine; Models, Molecular; Molecular Docking Simulation; Mutation; NADP; Protein Conformation; Protein Structure, Secondary; Quantum Theory; Tetrahydrofolate Dehydrogenase | 2017 |
Maternal methyl donor and cofactor supplementation in late pregnancy increases β-cell numbers at 16 days of life in growth-restricted twin lambs.
Topics: Animals; Animals, Newborn; Blood Glucose; Body Composition; Case-Control Studies; Cell Count; Cobalt; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Methionine; Pancreas; Pregnancy; Pregnancy, Twin; Prenatal Exposure Delayed Effects; Sheep; Sulfur | 2017 |
Relevance of plasma levels of free homocysteine and methionine as risk predictors for ischemic stroke in the young.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Odds Ratio; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6; Young Adult | 2018 |
Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits.
Topics: Animals; Antipsychotic Agents; Basic Helix-Loop-Helix Transcription Factors; CA1 Region, Hippocampal; Clozapine; Developmental Disabilities; Disease Models, Animal; Female; Folic Acid; Haloperidol; Humans; Male; Methionine; Mice; Neurogenesis; Neuronal Plasticity; One-Carbon Group Transferases; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Schizophrenia; Stereotyped Behavior; Tetrahydrofolates | 2018 |
Analysis of Homeostatic Mechanisms in Biochemical Networks.
Topics: Computer Simulation; Feedback, Physiological; Folic Acid; Homeostasis; Humans; Kinetics; Mathematical Concepts; Metabolic Networks and Pathways; Methionine; Models, Biological; Systems Biology | 2017 |
Circulating Folate, Vitamin B6, and Methionine in Relation to Lung Cancer Risk in the Lung Cancer Cohort Consortium (LC3).
Topics: Adult; Aged; Aged, 80 and over; Asia; Australia; Case-Control Studies; Cotinine; Europe; Female; Folic Acid; Humans; Incidence; Lung Neoplasms; Male; Methionine; Middle Aged; Prospective Studies; Protective Factors; Risk Factors; Sex Factors; Smoking; United States; Vitamin B 6 | 2018 |
Late-gestation maternal dietary methyl donor and cofactor supplementation in sheep partially reverses protection against allergic sensitization by IUGR.
Topics: Animals; Cobalt; Dermatitis; Dietary Supplements; Disease Models, Animal; DNA Methylation; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; Hypersensitivity; Immunoglobulin E; Mast Cells; Methionine; Ovalbumin; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Pyroglyphidae; Sheep, Domestic; Skin; Sulfur | 2018 |
Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure.
Topics: Animals; Female; Folic Acid; Glycine Dehydrogenase (Decarboxylating); Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Neural Tube; Neural Tube Defects | 2017 |
The folate-binding module of Thermus thermophilus cobalamin-dependent methionine synthase displays a distinct variation of the classical TIM barrel: a TIM barrel with a `twist'.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Folic Acid; Methionine; Models, Molecular; Protein Conformation; Sequence Homology; Thermus thermophilus; Vitamin B 12 | 2018 |
Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring.
Topics: Animals; Animals, Newborn; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Female; Folic Acid; Gene Expression; Lipid Metabolism; Liver; Male; Methionine; Micronutrients; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12; Vitamin B 6; Zebrafish; Zebrafish Proteins | 2018 |
Methyl-Donor and Cofactor Nutrient Intakes in the First 2-3 Years and Global DNA Methylation at Age 4: A Prospective Cohort Study.
Topics: Child, Preschool; Choline; Diet; Diet Records; Dietary Supplements; DNA Methylation; Female; Folic Acid; Humans; Linear Models; Longitudinal Studies; Male; Mental Recall; Methionine; Mouth Mucosa; Nutrition Assessment; Prospective Studies; Riboflavin; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6 | 2018 |
Oxidative stress and dietary micronutrient deficiencies contribute to overexpression of epigenetically regulated genes by lupus T cells.
Topics: Adult; Aged; Case-Control Studies; CD4-Positive T-Lymphocytes; Choline; Diet; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Female; Flow Cytometry; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Methionine; Micronutrients; Middle Aged; Oxidative Stress; Peroxynitrous Acid; Riboflavin; T-Lymphocytes; Vitamin B 12; Vitamin B 6; Young Adult; Zinc | 2018 |
Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.
Topics: Cell Line, Tumor; Cell Nucleus; Citric Acid Cycle; DNA Methylation; DNA, Mitochondrial; Epigenesis, Genetic; Folic Acid; HEK293 Cells; Humans; Methionine; Mitochondria; NAD; Osteoblasts; Oxidation-Reduction; Serine; Tricarboxylic Acids | 2018 |
Evaluation of tracer labelled methionine load test in vitamin B-12 deficient adolescent women.
Topics: Administration, Oral; Adolescent; Body Mass Index; Carbon Dioxide; Carbon Isotopes; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Iron; Methionine; Serologic Tests; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Intake of methyl-related nutrients and risk of pancreatic cancer in a population-based case-control study in Minnesota.
Topics: Adult; Aged; Case-Control Studies; Diet; Dietary Supplements; DNA Methylation; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Minnesota; Odds Ratio; Pancreatic Neoplasms; Risk Factors; Vitamin B 12; Vitamin B 6 | 2018 |
Betaine or folate can equally furnish remethylation to methionine and increase transmethylation in methionine-restricted neonates.
Topics: Animals; Animals, Newborn; Betaine; Blood; Choline; Female; Folic Acid; Male; Methionine; Methylation; Swine; Vitamin U | 2018 |
High methionine, low folate and low vitamin B6/B12 (HM-LF-LV) diet causes neurodegeneration and subsequent short-term memory loss.
Topics: Animals; Dose-Response Relationship, Drug; Folic Acid; Male; Memory Disorders; Memory, Short-Term; Methionine; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2018 |
Effect of maternal or post-weaning methyl donor supplementation on growth performance, carcass traits, and meat quality of pig offspring.
Topics: Animal Feed; Animals; Betaine; Body Weight; Dietary Supplements; Female; Folic Acid; Humans; Male; Maternal Nutritional Physiological Phenomena; Meat; Methionine; Pregnancy; Swine; Weaning | 2019 |
Two-carbon folate cycle of commensal Lactobacillus reuteri 6475 gives rise to immunomodulatory ethionine, a source for histone ethylation.
Topics: Amino Acids; Carbon; Cell Proliferation; Cells, Cultured; Culture Media; Ethionine; Folic Acid; Histones; Homocysteine; Humans; Immunomodulation; Limosilactobacillus reuteri; Methionine; Methylation; Microbiota; Probiotics; THP-1 Cells; Tumor Necrosis Factor-alpha | 2019 |
Paternal methyl donor deficient diets during development affect male offspring behavior and memory-related gene expression in mice.
Topics: Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Choline; Diet; DNA Methylation; Epigenesis, Genetic; Fear; Folic Acid; Gene Expression; Male; Methionine; Mice; Mice, Inbred C57BL; Receptors, Neuropeptide Y | 2019 |
Methionine Antagonizes
Topics: 4-Aminobenzoic Acid; Aminosalicylic Acid; Antitubercular Agents; Bacterial Proteins; Biotin; Drug Antagonism; Drug Resistance, Bacterial; Folic Acid; Methionine; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis | 2018 |
Dietary intake and food sources of one-carbon metabolism nutrients in preschool aged children.
Topics: Australia; Child Nutritional Physiological Phenomena; Child, Preschool; Choline; Diet; Female; Folic Acid; Humans; Male; Methionine; Nutrients; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2019 |
Dietary intake of nutrients involved in folate-mediated one-carbon metabolism and risk for endometrial cancer.
Topics: Aged; Carbon; Case-Control Studies; Diet; Endometrial Neoplasms; Female; Folic Acid; Humans; Methionine; Middle Aged; Obesity; Overweight; Proportional Hazards Models; Prospective Studies; Risk Factors; Vitamin B Complex | 2019 |
Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatitis.
Topics: Animals; Biomarkers; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Folate Receptor 2; Folic Acid; Humans; Liver; Macrophages; Male; Methionine; Mice, Inbred C57BL; Molecular Imaging; Non-alcoholic Fatty Liver Disease; Organotechnetium Compounds; Predictive Value of Tests; Radiopharmaceuticals; Rats, Sprague-Dawley; Tomography, Emission-Computed, Single-Photon | 2019 |
One-Carbon Cofactor Intake and Risk of Neural Tube Defects Among Women Who Meet Folic Acid Recommendations: A Multicenter Case-Control Study.
Topics: Adult; Betaine; Carbon; Case-Control Studies; Choline; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Methionine; Neural Tube Defects; Odds Ratio; Pregnancy; Risk Factors; Socioeconomic Factors; United States; Vitamin B 12; Vitamin B 6 | 2019 |
Association between polymorphisms of a folate - homocysteine - methionine - SAM metabolising enzyme gene and multiple sclerosis in a Polish population.
Topics: Adult; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Multiple Sclerosis; Poland | 2019 |
The concomitant lower concentrations of vitamins B6, B9 and B12 may cause methylation deficiency in autistic children.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Autism Spectrum Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cystathionine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Mass Spectrometry; Methionine; Methylation; Mutation; Oxidation-Reduction; Phenotype; Vitamin B 12; Vitamin B 6 | 2019 |
A novel approach in the management of hyperhomocysteinemia.
Topics: Alcohol Oxidoreductases; Animals; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Endothelial Cells; Folic Acid; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Kidney; Life Style; Liver; Methionine; Models, Theoretical; Vitamin B 12; Vitamin B 6 | 2019 |
Folate can promote the methionine-dependent reprogramming of glioblastoma cells towards pluripotency.
Topics: Cell Line, Tumor; Cell Proliferation; Cellular Reprogramming; Cytosol; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Meningioma; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Neoplastic Stem Cells; Pluripotent Stem Cells; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 2019 |
[Chronic inflammatory demyelinating polyradiculoneuropathy associated with treatment using intraduodenal infusion of levodopa-carbidopa].
Topics: Antiparkinson Agents; Carbidopa; Diagnosis, Differential; Dopamine; Drug Combinations; Duodenum; Female; Folic Acid; Humans; Infusions, Parenteral; Levodopa; Metabolic Networks and Pathways; Methionine; Middle Aged; Parkinson Disease; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | 2019 |
One-carbon metabolism, folate, zinc and translation.
Topics: Carbon; Folic Acid; Iron; Methionine; Zinc | 2020 |
Low protein diet and methyl-donor supplements modify testicular physiology in mice.
Topics: Animals; Betaine; Choline; Diet, Protein-Restricted; Dietary Supplements; Fatty Acids; Folic Acid; Male; Methionine; Mice; Testis; Vitamin B 12 | 2020 |
Induced DNA hypomethylation by Folic Acid Deprivation in Bovine Fibroblast Donor Cells Improves Reprogramming of Somatic Cell Nuclear Transfer Embryos.
Topics: Animals; Cattle; Cells, Cultured; DNA Methylation; Embryo, Mammalian; Female; Fibroblasts; Folic Acid; Gene Expression; Homocysteine; Methionine; Nuclear Transfer Techniques; Octamer Transcription Factor-3; Promoter Regions, Genetic | 2020 |
One-carbon metabolism-related micronutrients intake and risk for hepatocellular carcinoma: A prospective cohort study.
Topics: Carbon; Carcinoma, Hepatocellular; Diet; Dietary Supplements; Eating; Female; Folic Acid; Humans; Liver Neoplasms; Male; Methionine; Micronutrients; Middle Aged; Nutritional Status; Prospective Studies; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2020 |
The effect of methionine and folic acid administered in ovo on the hematological parameters of chickens (Gallus gallus domesticus).
Topics: Animals; Chick Embryo; Chickens; Folic Acid; Methionine; Zygote | 2020 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice.
Topics: Adenosylhomocysteinase; Animals; Betaine-Homocysteine S-Methyltransferase; Carbon; Disease Progression; Fibrosis; Folic Acid; Glycine N-Methyltransferase; Liver; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Polychlorinated Dibenzodioxins | 2020 |
Exercise during pregnancy mitigates the adverse effects of maternal obesity on adult male offspring vascular function and alters one-carbon metabolism.
Topics: Animals; Aorta; Endothelium, Vascular; Female; Folic Acid; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Obesity, Maternal; Physical Conditioning, Animal; Pregnancy; Prenatal Exposure Delayed Effects | 2020 |
Culture Conditions Affect Chemical-Induced Developmental Toxicity
Topics: Animals; Cell Culture Techniques; Cell Line; Embryonic Stem Cells; Folic Acid; Methionine; Methotrexate; Mice; Neural Stem Cells | 2020 |
In Silico Prediction of Metabolic Fluxes in Cancer Cells with Altered S-adenosylmethionine Decarboxylase Activity.
Topics: Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Antineoplastic Agents; Computer Simulation; Epigenesis, Genetic; Folic Acid; Glutathione; Humans; Methionine; Models, Biological; Neoplasms; Phenotype; Polyamines; Serine; Taurine; Uric Acid | 2021 |
[Remethylation disorders: about two cases].
Topics: Alcoholism; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Psychotic Disorders; Vitamin B 12 | 2020 |
Alterations in One-Carbon Metabolism in Celiac Disease.
Topics: Adolescent; Carbon; Celiac Disease; Child; Child, Preschool; Choline; Cross-Sectional Studies; Diet, Gluten-Free; Female; Folic Acid; Humans; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Methionine | 2020 |
Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.
Topics: Adenosylhomocysteinase; Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal; Folic Acid; Gene Expression Regulation, Enzymologic; Glycine Hydroxymethyltransferase; Homocysteine; Homocystinuria; Humans; Liver; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Polyamines | 2021 |
Association between methionine cycle metabolite-related diets and mild cognitive impairment in older Chinese adults: a population-based observational study.
Topics: Aged; China; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Diet; Folic Acid; Humans; Methionine; Middle Aged; Risk Factors | 2022 |
Four families of folate-independent methionine synthases.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Archaeal Proteins; Bacterial Proteins; Biosynthetic Pathways; Folic Acid; Homocysteine; Iron-Sulfur Proteins; Methionine; Models, Chemical; Molecular Structure; Multigene Family; Oxygen; Tetrahydrofolates; Vitamin B 12 | 2021 |
Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines.
Topics: Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choline; Folic Acid; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; Methionine; Methylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vitamin B 12 | 2021 |
Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Topics: Acetylgalactosamine; Adult; Arginine; Cystathionine beta-Synthase; Female; Folic Acid; Heme; Homeostasis; Homocysteine; Homocystinuria; Humans; Hydroxymethylbilane Synthase; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Porphyria, Acute Intermittent; Pyridoxal Phosphate; Pyrrolidines; Young Adult | 2021 |
Maternal supplementation with cobalt sources, folic acid, and rumen-protected methionine and its effects on molecular and functional correlates of the immune system in neonatal Holstein calves.
Topics: Animals; Animals, Newborn; Cattle; Cobalt; Diet; Dietary Supplements; Female; Folic Acid; Male; Methionine; Neutrophils; Pregnancy; Rumen | 2021 |
Dietary Methyl-Group Donor Intake and Breast Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Topics: Adult; Aged; Betaine; Breast Neoplasms; Choline; Diet; Europe; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Prospective Studies; Risk Factors | 2021 |
Regulation of the one carbon folate cycle as a shared metabolic signature of longevity.
Topics: Animals; Caenorhabditis elegans; Carbon; Folic Acid; Insulin; Longevity; Metabolic Networks and Pathways; Metabolome; Methionine; Mice; Mitochondria; Mutation; Peptides; Signal Transduction; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidylate Synthase | 2021 |
Metabolic and molecular signatures of improved growth in Atlantic salmon (
Topics: Animals; Folic Acid; Methionine; Racemethionine; Salmo salar; Vitamin B 6; Vitamins | 2022 |
Association of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer: the Japan Public Health Center-based (JPHC) prospective study.
Topics: Aged; Alcohol Drinking; Eating; Esophageal Neoplasms; Female; Folic Acid; Follow-Up Studies; Humans; Japan; Male; Methionine; Middle Aged; Prognosis; Prospective Studies; Public Health; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamins | 2021 |
Methionine synthase supports tumour tetrahydrofolate pools.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Methionine; Methylation; Mutation; Neoplasms; Purines; Tetrahydrofolates; Vitamin B 12 Deficiency | 2021 |
In vitro cytotoxicity, macromolecular interaction and antioxidant potential of dual coated selenium nanoparticles.
Topics: Antioxidants; DNA; Folic Acid; Methionine; Nanoparticles; Selenium; Serum Albumin, Bovine | 2022 |
Folate supplementation during oocyte maturation positively impacts the folate-methionine metabolism in pre-implantation embryos.
Topics: Animals; Blastocyst; Dietary Supplements; Embryonic Development; Female; Fertilization in Vitro; Folic Acid; In Vitro Oocyte Maturation Techniques; Methionine; Oocytes; Pregnancy | 2022 |
Dietary methyl donor nutrients, DNA mismatch repair polymorphisms, and risk of colorectal cancer based on microsatellite instability status.
Topics: Case-Control Studies; Choline; Colonic Neoplasms; Colorectal Neoplasms; Diet; DNA Mismatch Repair; Folic Acid; Humans; Methionine; Microsatellite Instability; Niacin; Nutrients; Polymorphism, Genetic; Risk Factors | 2022 |
Methyl Metabolism and the Clock: An Ancient Story With New Perspectives.
Topics: Animals; Circadian Rhythm; Folic Acid; Humans; Mammals; Methionine; Methylation; S-Adenosylmethionine | 2022 |
Supplementation of sulfur and folic acid improves performance of broiler chicken fed suboptimal concentrations of dietary methionine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Supplements; Folic Acid; Male; Methionine; Sulfur; Weight Gain | 2022 |
Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA.
Topics: Animals; Diet; Folic Acid; Liver Neoplasms, Experimental; Methionine; Methionine Adenosyltransferase; Mice | 2022 |
Dietary intake of one-carbon metabolism-related nutrients and hepatocellular carcinoma survival in the Guangdong Liver Cancer Cohort.
Topics: Carbon; Carcinoma, Hepatocellular; Cohort Studies; Diet; Eating; Folic Acid; Humans; Liver Neoplasms; Methionine; Nutrients; Prospective Studies; Risk Factors | 2022 |
Vitamin B
Topics: Animals; Fatty Acids; Fibrosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Qa-SNARE Proteins; Vitamin B 12; Vitamins | 2022 |
Hyperhomocysteinemia in acute hepatic porphyria (AHP) and implications for treatment with givosiran.
Topics: Clinical Trials as Topic; Cystathionine beta-Synthase; Folic Acid; Heme; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Porphyrias, Hepatic; Pyridoxine; RNA, Small Interfering; Sulfur; Vitamin B 6 | 2022 |
Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Caenorhabditis elegans; Carbon; Dithiothreitol; Folic Acid; Homocysteine; Hydrogen Sulfide; Ligases; Lipids; Mercaptoethanol; Methionine; Methyltransferases; Nucleic Acids; Oxygen; Reducing Agents; S-Adenosylmethionine; Sulfhydryl Compounds; Vitamin B 12; Vitamins | 2022 |
Characterization of Choline Nutriture among Adults and Children with Phenylketonuria.
Topics: Adult; Child; Choline; Female; Folic Acid; Humans; Methionine; Nutrition Surveys; Phenylalanine; Phenylketonurias; Pregnancy; Vitamin B 12; Vitamins | 2022 |
Stage specific gene expression of folate mediated one-carbon metabolism enzymes and transporters in buffalo oocytes and pre-implantation embryos.
Topics: Animals; Buffaloes; Carbon; Embryonic Development; Female; Fertilization in Vitro; Folic Acid; Folic Acid Transporters; Gene Expression; Methionine; Oocytes; Pregnancy | 2022 |
Intracellular Metabolomics Identifies Efflux Transporter Inhibitors in a Routine Caco-2 Cell Permeability Assay-Biological Implications.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Caco-2 Cells; Carbon; Folic Acid; Humans; Membrane Transport Proteins; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Permeability; Thymidylate Synthase | 2022 |
Impact of Methionine Synthase Reductase Polymorphisms in Chronic Myeloid Leukemia Patients.
Topics: Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methionine | 2022 |
One-carbon metabolism-related nutrients intake is associated with lower risk of preeclampsia in pregnant women: a matched case-control study.
Topics: Case-Control Studies; Choline; Eating; Female; Folic Acid; Humans; Methionine; Nutrients; Pre-Eclampsia; Pregnancy; Pregnant Women; Pyridoxine; Racemethionine; Vitamin B 12; Vitamin B 6; Vitamins | 2022 |
Changes in Dietary Intake of Methionine, Folate/Folic Acid and Vitamin B12 and Survival in Postmenopausal Women with Breast Cancer: A Prospective Cohort Study.
Topics: Animals; Eating; Female; Folic Acid; Methionine; Neoplasms; Postmenopause; Prospective Studies; Racemethionine; Risk Factors; Vitamin B 12 | 2022 |
Comparative analysis of methyl-donor nutrient intakes and RCPM cognitive performance among school-aged children.
Topics: Child; Cognition; Cross-Sectional Studies; Eating; Folic Acid; Ghana; Humans; Intelligence Tests; Methionine; Vitamins; Zinc | 2022 |
Study on the relationship between genetic polymorphism of reductive folic acid carrier and the risk of neural tube defects.
Topics: Case-Control Studies; Child; Female; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors | 2023 |
One-carbon metabolite supplementation to heifers for the first 14 d of the estrous cycle alters the plasma and hepatic one-carbon metabolite pool and methionine-folate cycle enzyme transcript abundance in a dose-dependent manner.
Topics: Animals; Carbon; Cattle; Choline; Dietary Supplements; Estrous Cycle; Female; Folic Acid; Liver; Methionine; Racemethionine; Rumen; S-Adenosylmethionine | 2023 |
One-carbon metabolism and related pathways in ruminal and small intestinal epithelium of lactating dairy cows.
Topics: Amino Acids; Animals; Antioxidants; Betaine; Carbon; Cattle; Creatine; Diet; Duodenum; Female; Folic Acid; Glutathione; Intestinal Mucosa; Lactation; Methionine; Milk; Rumen | 2023 |
Effect of Ethanol-Induced Methyl Donors Consumption on the State of Hypomethylation in Cervical Cancer.
Topics: Animals; Cell Line, Tumor; DNA; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Methionine; Mice; RNA, Messenger; Uterine Cervical Neoplasms | 2023 |
Conformational switching and flexibility in cobalamin-dependent methionine synthase studied by small-angle X-ray scattering and cryoelectron microscopy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cryoelectron Microscopy; Escherichia coli; Folic Acid; Methionine; Scattering, Small Angle; Vitamin B 12; X-Ray Diffraction; X-Rays | 2023 |
[Assessment of the role of nutritional and genetic determinants in the formation of the risk of diseases associated with folate cycle disorders in the population of the Omsk region].
Topics: Adult; Case-Control Studies; Choline; Female; Folic Acid; Genotype; Humans; Male; Methionine; Polymorphism, Genetic | 2023 |
Plasma One-Carbon Metabolism-Related Micronutrients and the Risk of Breast Cancer: Involvement of DNA Methylation.
Topics: Breast Neoplasms; Carbon; Case-Control Studies; Choline; Cysteine; DNA Methylation; Female; Folic Acid; Humans; Methionine; Micronutrients; Racemethionine; S-Adenosylmethionine; Trace Elements | 2023 |
Periconceptional intakes of methyl donors and other micronutrients involved in one-carbon metabolism may further reduce the risk of neural tube defects in offspring: a United States population-based case-control study of women meeting the folic acid recom
Topics: Betaine; Carbon; Case-Control Studies; Choline; Female; Folic Acid; Humans; Methionine; Micronutrients; Neural Tube Defects; Racemethionine; Trace Elements; Vitamin B 6 | 2023 |
The importance of preconception Hcy testing: identification of a folate trap syndrome in a woman attending an assisted reproduction program.
Topics: Female; Folic Acid; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Reproduction; S-Adenosylmethionine | 2023 |
Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Folic Acid; Methionine; S-Adenosylmethionine; Vitamin B 12 | 2023 |