Compounds > methionine
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methionine and cgs 26129

methionine has been researched along with cgs 26129 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alton, KB; Alvarez, N; Hernandez, A; Patrick, JE1
Balwierczak, JL; Jeng, AY; Kukkola, PJ; Savage, P1
Balwierczak, JL; Graybill, SC; Hopkins, MF; Jeng, AY; Lappe, RW; Savage, P; Sperbeck, DM; Stanton, JL; Trapani, AJ1
Bernardino, V; Chintala, M; Chiu, PJ; Vemulapalli, S1
Chiu, PJ; Foster, C; Haslanger, M; Neustadt, B; Smith, EM; Sybertz, EJ; Vemulapalli, S; Watkins, RW1
Banfield, CR; Batra, V; Fettner, SH; Kosoglou, T; Pai, S; Zhu, GR1
Burrell, LM; Casely, D; Farina, N; Johnston, CI; Risvanis, J; Woollard, D1

Trials

1 trial(s) available for methionine and cgs 26129

ArticleYear
Pharmacokinetic-pharmacodynamic (PK-PD) modeling for a new antihypertensive agent (neutral metalloendopeptidase inhibitor SCH 42354) in patients with mild to moderate hypertension.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:5

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Humans; Hypertension; Male; Methionine; Middle Aged; Placebos; Prodrugs; Protease Inhibitors

1995

Other Studies

7 other study(ies) available for methionine and cgs 26129

ArticleYear
High-performance liquid chromatographic determination of N-[2(S)-(mercaptomethyl)-3-(2-methylphenyl)-1-oxopropyl]-L-methionine, the active plasma metabolite of a prodrug atriopeptidase inhibitor (SCH 42495), using a thiol selective (Au/Hg) amperometric de
    Journal of chromatography, 1992, Sep-02, Volume: 579, Issue:2

    Topics: Chromatography, High Pressure Liquid; Gold; Humans; Hypertension; Mercury; Methionine; Neprilysin; Sulfhydryl Compounds

1992
Effects of metalloprotease inhibitors on smooth muscle endothelin-converting enzyme activity.
    Biochemical pharmacology, 1995, Jan-31, Volume: 49, Issue:3

    Topics: Animals; Aspartic Acid Endopeptidases; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Enzyme Activation; Glycopeptides; Metalloendopeptidases; Methionine; Muscle, Smooth, Vascular; Propionates; Protein Precursors; Structure-Activity Relationship; Swine; Thiorphan

1995
Effects of metalloprotease inhibitors on the conversion of proendothelin-1 to endothelin-1.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:5

    Topics: Animals; Aspartic Acid Endopeptidases; Benzazepines; Blood Pressure; Coronary Vessels; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Endothelium, Vascular; Glycopeptides; In Vitro Techniques; Male; Metalloendopeptidases; Methionine; Muscle Contraction; Muscle, Smooth, Vascular; Neprilysin; Propionates; Protein Precursors; Rats; Rats, Sprague-Dawley; Swine; Thiorphan

1993
Attenuation of ischemic acute renal failure by phosphoramidon in rats.
    Pharmacology, 1993, Volume: 47, Issue:3

    Topics: Acute Kidney Injury; Animals; Aspartic Acid Endopeptidases; Disease Models, Animal; Endothelin-Converting Enzymes; Endothelins; Glomerular Filtration Rate; Glycopeptides; Infusions, Intravenous; Male; Metalloendopeptidases; Methionine; Neprilysin; Rats

1993
Atrial natriuretic factor potentiating and hemodynamic effects of SCH 42495, a new, neutral metalloendopeptidase inhibitor.
    American journal of hypertension, 1993, Volume: 6, Issue:5 Pt 1

    Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Autonomic Nervous System; Bradykinin; Desoxycorticosterone; Drug Synergism; Hemodynamics; Hypertension; Kidney; Male; Metalloendopeptidases; Methionine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Mutant Strains; Sodium Chloride

1993
Inhibition of neutral endopeptidase, the degradative enzyme for natriuretic peptides, in rat kidney after oral SCH 42495.
    Clinical science (London, England : 1979), 1997, Volume: 93, Issue:1

    Topics: Administration, Oral; Animals; Atrial Natriuretic Factor; Binding, Competitive; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Iodine Radioisotopes; Iodobenzenes; Kidney; Methionine; Neprilysin; Peptidyl-Dipeptidase A; Prodrugs; Rats; Rats, Sprague-Dawley; Renin; Time Factors

1997
SCH 42495.
    Drugs in R&D, 1999, Volume: 1, Issue:4

    Topics: Drugs, Investigational; Endopeptidases; Heart Failure; Humans; Hypertension; Methionine; Prodrugs; Protease Inhibitors

1999