Page last updated: 2024-08-17

methionine and acetylcysteine

methionine has been researched along with acetylcysteine in 120 studies

Research

Studies (120)

TimeframeStudies, this research(%)All Research%
pre-199046 (38.33)18.7374
1990's20 (16.67)18.2507
2000's27 (22.50)29.6817
2010's26 (21.67)24.3611
2020's1 (0.83)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adriaenssens, P; Ballantyne, A; Park, J; Prescott, LF; Proudfoot, AT1
Salemnick, G; Stöhrer, G1
van Zwieten, PA1
Moldéus, P; Orrenius, S; Thor, H1
Adam, RD; Critchley, JA; Illingworth, RN; Prescott, LF; Proudfoot, AT; Stewart, MJ1
Crome, P; Goulding, R; Helliwell, M; Meredith, TJ; Vale, JA; Volans, GN; Widdop, B1
Peterson, RG; Rumack, BH1
Prescott, LF3
Austin, F; Carloss, H; Forrester, J; Fuson, T1
Marquardt, ED1
Gasco, E; Gimenez, A; Puertes, IR; Viña, J; Viña, JR1
Asensi, M; Estrela, JM; Hernandez, R; Puertes, IR; Terradez, P; Viña, J1
Bray, GP; Tredger, JM; Williams, R1
Asensi, M; Ferrer, JV; Gascó, E; Pallardó, FV; Sastre, J; Viña, J1
Cozzolino, P; Daino, L; Feo, F; Frassetto, S; Garcea, R; Pascale, R; Ruggiu, ME; Vannini, MG1
Furukawa, T; Palacin, M; Perez, C; Viña, J; Viña, JR1
Bjerrum, OW; Borregaard, N; Jensen, HS1
Drozdz, R; Naskalski, JW; Sznajd, J1
Boobis, AR; Davies, DS; Tee, LG1
Meredith, TJ; Prescott, LF; Vale, JA1
Bässler, KH; Grötz, KA; Langer, K; Neuhäuser, M; Wandira, JA1
Davis, M1
Hathcock, JN; Reicks, MM1
Friedman, M; Gumbmann, MR1
Read, RB; Tredger, JM; Williams, R1
Aalen, O; Ingebrigtsen, K; Nafstad, I; Skoglund, LA1
Ioannides, C; Pratt, S1
Jørgensen, LN1
Bailey, KR; Sheffner, AL1
Henry, J; Volans, G1
Critchley, JA; Prescott, LF1
Tateishi, M1
Birkett, DJ; Drew, R; Miners, JO1
Nielsen, I; Pedersen, RS1
Hopkins, S1
Black, M1
Goulding, R; Meredith, TJ1
Pflüger, KH1
Breen, KJ; Bury, RW; Desmond, PV; Forge, BH; Mashford, ML; Whelan, G1
Dayton, H; Fretthold, D; Leickly, F; Sunshine, I; Thompson, WL; Van de Graaff, WB1
Klein-Schwartz, W; Oderda, GM1
Gilligan, JE; Kemp, R; Pain, R; Phillips, PJ1
Davis, M; Smith, HM; Tredger, JM; Williams, R1
Estrela, JM; Romero, FJ; Viña, J; Viña, JR1
Krienke, EG; von Mühlendahl, KE1
Goulding, R; Meredith, TJ; Vale, JA1
Proudfoot, AT; Vale, JA1
Elfarra, AA1
Antczak, A; Bialasiewicz, P; Krol, M; Nowak, D; Pietras, T1
Bossuyt, PM; de Jong, JM; Louwerse, ES; Timmer, JG; Vyth, A1
Dietrich, A; Ehrlich, W; Kröger, H; Kurpisz, M; Lange, R; Ohde, M1
Baek, Y; Barama, A; Boudjema, K; Jaeck, D; Kitamura, N; Kumada, K; Nagasaki, H; Nakano, H; Suzuki, T; Tatsuno, M; Yamaguchi, M1
Bonassi, S; De Biase, A; Deeva, IB; Degan, P; Doronin, YK; Iaccarino, M; Korkina, LG; Oral, R; Pagano, G; Warnau, M1
Barber, T; García, C; Puertes, IR; Sastre, J; Triguero, A; Viña, JR1
Behr, J; Degenkolb, B; Krombach, F; Maier, K; Vogelmeier, C1
MacConnachie, AM1
Bennett, MJ; Kearse, KP; Van Leeuwen, JE1
Cotgreave, IA; Söderholm, K; Voskoboinik, I1
Birenbaum, DS; Lopez, BL; Ma, XI; Snyder, JW1
Fujiwara, Y; Kigawa, G; Kitamura, N; Kumada, K; Kuzume, M; Nagasaki, H; Nakano, H; Sasaki, J; Shimura, H; Takeuchi, S; Yamaguchi, M; Yoshida, K1
Crowe, M; Wright, B1
Dringen, R; Hamprecht, B1
Kröning, R; Lichtenstein, AK; Nagami, GT1
Clayton, J; Geeves, M; Nongthomba, U; Prinz, H; Schmitz, S; Sparrow, J; Veigel, C1
Law, R1
Béchet, DM; Ferrara, M; Obled, A; Omura, S; Roux, MP; Tournu, C1
Levine, R; Morrow, J; Sentürker, S; Shacter, E; Tschirret-Guth, R1
Elkon, H; Melamed, E; Offen, D1
Buckley, N; Eddleston, M4
Hak-Lemmers, HL; Peters, WH; Raijmakers, MT; Roes, EM; Schilders, GW; Steegers, EA; van Tits, LJ1
Alsalim, W; Fadel, M1
GUTMANN, HR; WOOD, JL1
Atmaca, G1
Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S1
Cataldi, TR; Nardiello, D1
Bartosz, G; Biliński, T; Kozioł, S; Krzepiłko, A; Zadrag, R; Zyracka, E1
Chen, SX; Liu, LY; Liu, YH; Sun, YX; Wu, JX1
Kurebayashi, H; Ohno, Y1
Capanni, C; Columbaro, M; D'Apice, MR; Foisner, R; Lattanzi, G; Maraldi, NM; Mattioli, E; Novelli, G; Riccio, M; Santi, S; Squarzoni, S1
Fichtl, B; Mückter, H; Walther, SC; Walther, UI1
Jin, Y; Li, G; Liao, Y; Lu, C; Lu, X; Tang, H1
Aytekin, M; Caylak, E; Halifeoglu, I1
Avnet, S; Baldini, N; Ghisu, S; Lattanzi, G; Maraldi, NM; Squarzoni, S; Zini, N1
Chen, C; Huang, D; Ji, W; Qi, Y; Zhang, Y1
Calderón-Cabrera, L; Durán-Galetta, MG; Ferreira, E; Galetta, D; Garcia, I; Lacruz, L; Naranjo, R; Pérez, B1
Hughes, WM; Kumar, M; Kundu, S; Moshal, KS; Sen, U; Tyagi, N; Tyagi, SC; Vacek, TP1
Buckley, N; Dawson, AH; Fernandopulle, BM; Ranganathan, SS; Senarathna, SM1
de Silva, V; Rathnayake, A1
Auclair, M; Bastard, JP; Boccara, F; Capeau, J; Caron-Debarle, M; Lefèvre, C; Vigouroux, C1
Park, WH; You, BR1
Balough, BJ; Clifford, RE; Coleman, JK; Jackson, RL; Kopke, RD; Liu, J1
Campbell, KC; Giordano, P; Hatzopoulos, S; Kochanek, K; Laurell, G; Lorito, G; Martini, A; Petruccelli, J; Skarzynski, H; Sliwa, L1
Burd, NA; Burke, LM; Castell, LM; Jeukendrup, A; Reid, MB; Stear, SJ1
Buckley, N; Fernandopulle, R; Senarathna, SM; Sri Ranganathan, S1
Elshorbagy, AK; Mattocks, DA; Orentreich, DS; Orentreich, N; Perrone, CE; Plummer, JD; Refsum, H; Valdivia-Garcia, M1
Ahmadi-Ashtiani, H; Allameh, A; Emami Aleagha, MS; Rastegar, H1
Rajguru, R1
Farrell, NP; Spell, SR1
Inomata, A; Nakae, D; Nakagawa, Y; Ogata, A1
Abdel-Latif, HA; Ali, MH; Messiha, BA1
Antoine, DJ; Dear, JW; Park, BK1
Gupta, S; Kruger, WD1
Weber, G; Zabel, R1
Buckley, NA; Dawson, AH; Isbister, GK1
Borović, ML; Borozan, S; Despotović, S; Djuric, D; Dragutinović, V; Ilić, S; Lalić, I; Milićević, Ž; Mitrović, D; Šćepanović, L; Šćepanović, R; Šćepanović, T; Šćepanović, V; Stojanović, M; Todorović, D1
Gailer, J1
Borges-Santos, MD; Burini, RC; Moreto, F; Yu, YM1
Borozan, S; Čolović, M; Djuric, D; Dragutinović, V; Krstić, D; Labudović-Borović, M; Mitrović, D; Šćepanović, L; Stojanović, M; Todorović, D1
Brok, J; Buckley, NA; Chiew, AL; Gluud, C1
Abdenur, JE; Boyer, M; Di Meo, I; Eftekharian, S; Sowa, M; Steenari, MR; Tiranti, V1
Andrejević, L; Cvetković, S; Djurić, D; Hrnčić, D; Jakovljević, V; Kostić, S; Labudović-Borović, M; Mićovic, Ž; Obrenović, R; Stamenković, A; Stanković, S1
Chai, Y; Song, Y; Wang, X; Yuan, R; Zhou, Y; Zhu, X1

Reviews

20 review(s) available for methionine and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Protective agents for acetaminophen overdose.
    Seminars in liver disease, 1986, Volume: 6, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cimetidine; Cysteamine; Glucuronates; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxides; Liver; Methionine; Necrosis; Propylthiouracil

1986
The treatment of acetaminophen poisoning.
    Annual review of pharmacology and toxicology, 1983, Volume: 23

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Antidotes; Aspartate Aminotransferases; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Glutathione; Humans; Liver; Methionine; Necrosis; Sulfhydryl Compounds

1983
Methylthiolated metabolites.
    Drug metabolism reviews, 1983, Volume: 14, Issue:6

    Topics: Acetylcysteine; Acetyltransferases; Animals; Biotransformation; Digestive System; Humans; Methionine; Methylation; Methyltransferases; Pharmaceutical Preparations; Sulfhydryl Compounds

1983
Acetaminophen hepatotoxicity.
    Gastroenterology, 1980, Volume: 78, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Glutathione; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Methionine

1980
Paracetamol.
    Postgraduate medical journal, 1980, Volume: 56, Issue:657

    Topics: Acetaminophen; Acetylcysteine; Adult; Animals; Chemical and Drug Induced Liver Injury; Child; Cysteamine; Dextropropoxyphene; Humans; Infant; Kidney Diseases; Methionine

1980
Paracetamol (acetaminophen) poisoning.
    Lancet (London, England), 1995, Aug-26, Volume: 346, Issue:8974

    Topics: Acetaminophen; Acetylcysteine; Dose-Response Relationship, Drug; Drug Overdose; Humans; Liver; Methionine

1995
Potential role of the flavin-containing monooxygenases in the metabolism of endogenous compounds.
    Chemico-biological interactions, 1995, Apr-28, Volume: 96, Issue:1

    Topics: Acetylcysteine; Animals; Cysteine; Glutathione; Homocysteine; Mammals; Methionine; Oxidation-Reduction; Oxygenases; Sulfoxides

1995
Paracetamol (acetaminophen) poisoning.
    Clinical evidence, 2002, Issue:7

    Topics: Acetaminophen; Acetylcysteine; Humans; Methionine; Poisoning; Randomized Controlled Trials as Topic; Suicide Prevention; Survival Rate; Treatment Outcome

2002
Paracetamol (acetaminophen) poisoning.
    Clinical evidence, 2002, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Humans; Methionine

2002
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Oral methionine compared with intravenous n-acetyl cysteine for paracetamol overdose.
    Emergency medicine journal : EMJ, 2003, Volume: 20, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Drug Overdose; Evidence-Based Medicine; Humans; Methionine

2003
Antioxidant effects of sulfur-containing amino acids.
    Yonsei medical journal, 2004, Oct-31, Volume: 45, Issue:5

    Topics: Acetylcysteine; Amino Acids, Sulfur; Antioxidants; Cysteine; Glutathione; Methionine; Structure-Activity Relationship; Taurine; Thioctic Acid; Tiopronin

2004
Paracetamol (acetaminophen) poisoning.
    Clinical evidence, 2004, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Humans; Methionine

2004
Yeast as a biosensor for antioxidants: simple growth tests employing a Saccharomyces cerevisiae mutant defective in superoxide dismutase.
    Acta biochimica Polonica, 2005, Volume: 52, Issue:3

    Topics: Acetylcysteine; Air; Antioxidants; Atmosphere; Biosensing Techniques; Cysteine; Lysine; Methionine; Mutation; Saccharomyces cerevisiae; Superoxide Dismutase

2005
Paracetamol (acetaminophen) poisoning.
    Clinical evidence, 2005, Issue:14

    Topics: Acetaminophen; Acetylcysteine; Humans; Methionine

2005
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 26.
    British journal of sports medicine, 2011, Volume: 45, Issue:14

    Topics: Acetylcysteine; Athletic Performance; Carbohydrates; Dietary Supplements; Humans; Methionine

2011
Military aircrew and noise-induced hearing loss: prevention and management.
    Aviation, space, and environmental medicine, 2013, Volume: 84, Issue:12

    Topics: Acetylcarnitine; Acetylcysteine; Aerospace Medicine; Aircraft; Anti-Inflammatory Agents; Antioxidants; Azoles; Creatine; Ear Protective Devices; Equipment Design; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Genetic Therapy; Hair Cells, Auditory; Head Protective Devices; Hearing Loss, Noise-Induced; Humans; Hyperbaric Oxygenation; Isoindoles; Magnesium; Methionine; Military Personnel; Nanomedicine; Neuroprotective Agents; Organoselenium Compounds; Regeneration; Resveratrol; Salicylic Acid; Stilbenes; Vitamins

2013
Paracetamol (acetaminophen) poisoning.
    BMJ clinical evidence, 2015, Oct-19, Volume: 2015

    Topics: Acetaminophen; Acetylcysteine; Charcoal; Gastric Lavage; Humans; Liver Transplantation; Methionine; Poisoning; Renal Dialysis; Treatment Outcome

2015
The effect of dietary modulation of sulfur amino acids on cystathionine β synthase-deficient mice.
    Annals of the New York Academy of Sciences, 2016, Volume: 1363

    Topics: Acetylcysteine; Amino Acids, Sulfur; Animals; Betaine; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Genotype; Homocystinuria; Humans; Metabolic Networks and Pathways; Methionine; Mice; Mice, Knockout; Mutation; Phenotype

2016
Interventions for paracetamol (acetaminophen) overdose.
    The Cochrane database of systematic reviews, 2018, 02-23, Volume: 2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Cysteamine; Dimercaprol; Drug Overdose; Gastric Lavage; Humans; Intestinal Absorption; Liver Failure, Acute; Liver Transplantation; Methionine; Randomized Controlled Trials as Topic

2018

Trials

4 trial(s) available for methionine and acetylcysteine

ArticleYear
Survival in patients with amyotrophic lateral sclerosis, treated with an array of antioxidants.
    Journal of the neurological sciences, 1996, Volume: 139 Suppl

    Topics: Acetylcysteine; Administration, Oral; Amyotrophic Lateral Sclerosis; Antioxidants; Capsules; Chelating Agents; Dithioerythritol; Dithiothreitol; Free Radical Scavengers; Gastric Juice; Humans; Injections, Subcutaneous; Methionine; Succimer; Sulfhydryl Reagents; Survival Analysis

1996
N-Acetylcysteine improves the disturbed thiol redox balance after methionine loading.
    Clinical science (London, England : 1979), 2003, Volume: 105, Issue:2

    Topics: Acetylcysteine; Adult; Antioxidants; Cross-Over Studies; Cysteine; Female; Homocysteine; Humans; Lipid Peroxidation; Male; Methionine; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sulfhydryl Compounds

2003
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation

2005
Comparative effects of acute-methionine loading on the plasma sulfur-amino acids in NAC-supplemented HIV+ patients and healthy controls.
    Amino acids, 2018, Volume: 50, Issue:5

    Topics: Acetylcysteine; Adult; Antiretroviral Therapy, Highly Active; Cysteine; Dietary Supplements; Female; Glutathione; HIV Infections; HIV-1; Humans; Male; Methionine; Middle Aged

2018

Other Studies

96 other study(ies) available for methionine and acetylcysteine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine.
    Lancet (London, England), 1977, Aug-27, Volume: 2, Issue:8035

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Evaluation; Female; Follow-Up Studies; Humans; Infusions, Parenteral; Male; Methionine; Middle Aged

1977
Oxidizing action of purine N-oxide esters.
    Cancer research, 1975, Volume: 35, Issue:1

    Topics: Acetylation; Acetylcysteine; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyclic N-Oxides; Cysteine; Esters; Guanine; Hydrogen-Ion Concentration; Iodides; Iodine; Mercaptopurine; Methionine; Oxidation-Reduction; Purines; Pyridines; Sulfates; Sulfhydryl Compounds; Tryptophan; Tyrosine; Uric Acid; Xanthines

1975
[Therapy of paracetamol poisoning].
    Nederlands tijdschrift voor geneeskunde, 1979, Feb-24, Volume: 123, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Methionine

1979
Metabolic activation and hepatotoxicity. Effect of cysteine, N-acetylcysteine, and methionine on glutathione biosynthesis and bromobenzene toxicity in isolated rat hepatocytes.
    Archives of biochemistry and biophysics, 1979, Volume: 192, Issue:2

    Topics: Acetylcysteine; Animals; Biotransformation; Bromobenzenes; Cysteine; Glutathione; In Vitro Techniques; Kinetics; Liver; Male; Maleates; Methionine; Microsomes, Liver; Phenobarbital; Rats

1979
Acetylcysteine for acetaminophen overdose.
    The Medical letter on drugs and therapeutics, 1979, Nov-30, Volume: 21, Issue:24

    Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Humans; Liver; Methionine

1979
Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning.
    British medical journal, 1979, Nov-03, Volume: 2, Issue:6198

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Infusions, Parenteral; Kidney Diseases; Liver Diseases; Male; Methionine; Middle Aged; Risk; Time Factors

1979
Intravenous N-acetylcysteine: the treatment of choice in paracetamol poisoning?
    British medical journal, 1979, Dec-01, Volume: 2, Issue:6202

    Topics: Acetaminophen; Acetylcysteine; Humans; Methionine

1979
Toxicity of acetaminophen overdose.
    JACEP, 1978, Volume: 7, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Cysteamine; Humans; Methionine

1978
The chief scientist reports ... prevention of hepatic necrosis following paracetamol overdosage.
    Health bulletin, 1978, Volume: 36, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver Diseases; Male; Methionine; Middle Aged; Scotland

1978
Acute acetaminophen intoxication.
    Southern medical journal, 1978, Volume: 71, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver; Male; Methionine; Suicide, Attempted

1978
Treatment of acetaminophen toxicity.
    American journal of hospital pharmacy, 1977, Volume: 34, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Humans; Methionine

1977
Impairment of cysteine synthesis from methionine in rats exposed to surgical stress.
    The British journal of nutrition, 1992, Volume: 68, Issue:2

    Topics: Acetylcysteine; Animals; Body Weight; Cells, Cultured; Cystathionine gamma-Lyase; Cysteine; Eating; Liver; Male; Methionine; Rats; Rats, Wistar; Stress, Physiological; Surgical Procedures, Operative

1992
Regulation of glutathione metabolism in Ehrlich ascites tumour cells.
    The Biochemical journal, 1992, Aug-15, Volume: 286 ( Pt 1)

    Topics: Acetylcysteine; Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cells, Cultured; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Kinetics; Liver; Male; Methionine; Mice; Mice, Inbred Strains; Rats; Reference Values; Subcellular Fractions

1992
S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models.
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mortality; S-Adenosylmethionine

1992
Age-related changes in glutathione synthesis in the eye lens.
    The Biochemical journal, 1990, Jul-15, Volume: 269, Issue:2

    Topics: Acetylcysteine; Adenosine Triphosphate; Aging; Animals; Cystathionine gamma-Lyase; Glutathione; Lens, Crystalline; Methionine; Mice; Oxidation-Reduction; Peroxides; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide

1990
Inhibition by ethanol of rat liver plasma membrane (Na+,K+)ATPase: protective effect of S-adenosyl-L-methionine, L-methionine, and N-acetylcysteine.
    Toxicology and applied pharmacology, 1989, Volume: 97, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Animals; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Ethanol; Female; Glutathione; Liver; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase

1989
Effect of oral glutathione on hepatic glutathione levels in rats and mice.
    The British journal of nutrition, 1989, Volume: 62, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adenosine Triphosphate; Animals; Cysteine; Fasting; Glutathione; Liver; Maleates; Methionine; Mice; Rats; Rats, Inbred Strains

1989
Prevention of tissue damage: inhibition of myeloperoxidase mediated inactivation of alpha 1-proteinase inhibitor by N-acetyl cysteine, glutathione, and methionine.
    Agents and actions, 1987, Volume: 22, Issue:3-4

    Topics: Acetylcysteine; alpha 1-Antitrypsin; Blood Proteins; Chlorides; Glutathione; Humans; Hydrogen Peroxide; Methionine; Pancreatic Elastase; Peroxidase; Protease Inhibitors

1987
Action of myeloperoxidase-hydrogen peroxide-chloride system on the egg white lysozyme.
    Acta biochimica Polonica, 1988, Volume: 35, Issue:4

    Topics: Acetylcysteine; Chlorides; Cystine; Egg White; Electrophoresis, Polyacrylamide Gel; Enzyme Repression; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Methionine; Muramidase; Peroxidase; Tryptophan

1988
N-acetylcysteine for paracetamol overdose.
    Lancet (London, England), 1986, Feb-08, Volume: 1, Issue:8476

    Topics: Acetaminophen; Acetylcysteine; Animals; Cricetinae; Glutathione; Humans; In Vitro Techniques; Liver; Methionine

1986
Why do patients still die from paracetamol poisoning?
    British medical journal (Clinical research ed.), 1986, Aug-09, Volume: 293, Issue:6543

    Topics: Acetaminophen; Acetylcysteine; Adult; Child, Preschool; Gastric Lavage; Humans; Methionine

1986
Utilization of methionine and N-acetyl-L-cysteine during long-term parenteral nutrition in the growing rat.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:9

    Topics: Acetylcysteine; Amino Acids; Animals; Body Weight; Male; Methionine; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains

1986
Effects of methionine deficiency and ethanol ingestion on acetaminophen metabolism in mice.
    The Journal of nutrition, 1987, Volume: 117, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Aniline Hydroxylase; Animals; Body Weight; Diet; Ethanol; Glutathione; Male; Methionine; Mice; Microsomes, Liver; Protein Biosynthesis; Sulfates

1987
Effect of sulfur amino acid supplementation of raw soy flour on the growth and pancreatic weights of rats.
    The Journal of nutrition, 1987, Volume: 117, Issue:6

    Topics: Acetylcysteine; Amino Acids, Sulfur; Animals; Body Weight; Cysteine; Cystine; Dietary Proteins; Male; Methionine; Nutritive Value; Organ Size; Pancreas; Plant Proteins, Dietary; Rats; Rats, Inbred Strains; Soybean Proteins

1987
Analysis of factors responsible for continuing mortality after paracetamol overdose.
    Human toxicology, 1986, Volume: 5, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Alcoholism; Antidotes; Dextropropoxyphene; Disseminated Intravascular Coagulation; Drug Combinations; Hepatic Encephalopathy; Humans; Liver Function Tests; Male; Methionine; Retrospective Studies

1986
Efficacy of paracetamol-esterified methionine versus cysteine or methionine on paracetamol-induced hepatic GSH depletion and plasma ALAT level in mice.
    Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Drug Compounding; Glutathione; Liver; Male; Methionine; Mice; Time Factors

1986
Mechanism of the protective action of n-acetylcysteine and methionine against paracetamol toxicity in the hamster.
    Archives of toxicology, 1985, Volume: 57, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cricetinae; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Glutathione; Liver; Male; Mesocricetus; Methionine; Organ Size

1985
[Survival after self-poisoning with 80 grams of paracetamol].
    Ugeskrift for laeger, 1985, Nov-04, Volume: 147, Issue:45

    Topics: Acetaminophen; Acetylcysteine; Female; Humans; Methionine; Middle Aged; Prognosis

1985
The reduction of experimentally induced inflammation by sulfhydryl compounds.
    Biochemical pharmacology, 1967, Jul-07, Volume: 16, Issue:7

    Topics: Acetylcysteine; Animals; Dexamethasone; Drug Synergism; Hydrocortisone; Inflammation; Male; Methionine; Penicillamine; Rabbits; Salicylates

1967
New approaches in managing drug overdosage and poisoning.
    British medical journal (Clinical research ed.), 1983, Jul-23, Volume: 287, Issue:6387

    Topics: Acetaminophen; Acetylcysteine; Adrenergic beta-Antagonists; Adult; Analgesics, Opioid; Child; Cholinesterase Inhibitors; Glucagon; Humans; Immunotherapy; Intestinal Absorption; Methionine; Naloxone; Physostigmine; Poisoning; Poisons; Self Administration

1983
ABC of poisoning. Analgesics: II--Paracetamol.
    British medical journal (Clinical research ed.), 1984, Oct-06, Volume: 289, Issue:6449

    Topics: Acetaminophen; Acetylcysteine; Analgesics; Diagnosis; Humans; Ipecac; Methionine; Therapeutic Irrigation; Time Factors

1984
Mechanism of action of paracetamol protective agents in mice in vivo.
    Biochemical pharmacology, 1984, Oct-01, Volume: 33, Issue:19

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Buthionine Sulfoximine; Cysteamine; Cysteine; Glutathione; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H

1984
[Paracetamol poisoning. Specific treatment with methionine or N-acetylcysteine?].
    Ugeskrift for laeger, 1984, May-14, Volume: 146, Issue:20

    Topics: Acetaminophen; Acetylcysteine; Antidotes; Humans; Methionine

1984
Paracetamol.
    Nursing mirror, 1980, Feb-14, Volume: 150, Issue:7

    Topics: Acetaminophen; Acetylcysteine; Humans; Methionine; Poisoning

1980
[Toxicology and therapy of paracetamol poisoning].
    Der Internist, 1980, Volume: 21, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Cysteamine; Drug Interactions; Ethanol; Gastric Lavage; Glutathione; Half-Life; Methionine; Phenobarbital; Poisoning

1980
Paracetamol self-poisoning: diagnosis, management, and outcome.
    The Medical journal of Australia, 1982, Jan-23, Volume: 1, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adolescent; Adult; Australia; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Female; Hospitalization; Humans; Injections, Intravenous; Liver Diseases; Liver Function Tests; Methionine; Middle Aged; Suicide, Attempted; Time Factors

1982
Adsorbent and cathartic inhibition of enteral drug absorption.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adsorption; Animals; Cathartics; Charcoal; Chemistry, Pharmaceutical; Dogs; Female; Intestinal Absorption; Male; Methionine; Mice; Resins, Plant; Time Factors

1982
Adsorption of oral antidotes for acetaminophen poisoning (methionine and n-acetylcysteine) by activated charcoal.
    Clinical toxicology, 1981, Volume: 18, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adsorption; Antidotes; Charcoal; Chemical Phenomena; Chemistry; Methionine

1981
Paracetamol concentrations, hepatotoxicity, and antidotes.
    British medical journal, 1980, Jan-12, Volume: 280, Issue:6207

    Topics: Acetaminophen; Acetylcysteine; Humans; Methionine; Risk; Time Factors

1980
Effects of sulphur-containing compounds on paracetamol activation and covalent binding in a mouse hepatic microsomal system.
    Toxicology letters, 1980, Volume: 5, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteamine; In Vitro Techniques; Male; Methionine; Mice; Microsomes, Liver; Mixed Function Oxygenases; Sulfur; Tiopronin

1980
Effect of acetaminophen (paracetamol) and its antagonists on glutathione (GSH) content in rat liver.
    Biochemical pharmacology, 1980, Jul-01, Volume: 29, Issue:13

    Topics: Acetaminophen; Acetylcysteine; Animals; Glutathione; In Vitro Techniques; Liver; Methionine; Rats; Time Factors

1980
[Paracetamol poisoning].
    Intensivmedizinische Praxis, 1980, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Kidney Tubular Necrosis, Acute; Liver; Methionine; Transaminases

1980
Treatment of severe acetaminophen poisoning with intravenous acetylcysteine.
    Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Cysteamine; Humans; Injections, Intravenous; Liver; Methionine

1981
Treatment of acetaminophen poisoning. The use of oral methionine.
    Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Humans; Liver; Methionine; Time Factors

1981
Protective effect of ambroxol against heat- and hydrogen peroxide-induced damage to lung lipids in mice.
    The European respiratory journal, 1994, Volume: 7, Issue:9

    Topics: Acetylcysteine; Ambroxol; Animals; Antioxidants; Heart; Hot Temperature; Hydrogen Peroxide; Lipid Peroxidation; Liver; Lung; Male; Methionine; Mice; Mice, Inbred BALB C; Pulmonary Surfactants

1994
Protection from acetaminophen-induced liver damage by the synergistic action of low doses of the poly(ADP-ribose) polymerase-inhibitor nicotinamide and the antioxidant N-acetylcysteine or the amino acid L-methionine.
    General pharmacology, 1997, Volume: 28, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Synergism; Male; Methionine; Mice; Mice, Inbred Strains; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors

1997
The effects of N-acetylcysteine and anti-intercellular adhesion molecule-1 monoclonal antibody against ischemia-reperfusion injury of the rat steatotic liver produced by a choline-methionine-deficient diet.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:3

    Topics: Acetylcysteine; Acid Phosphatase; Alanine Transaminase; Animals; Antibodies, Monoclonal; Aspartate Aminotransferases; Bile; Choline Deficiency; Fatty Liver; In Vitro Techniques; Intercellular Adhesion Molecule-1; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Methionine; Microscopy, Electron; Neutrophils; Perfusion; Rats; Rats, Wistar; Reperfusion Injury

1997
L-methionine induces stage-dependent changes of differentiation and oxidative activity in sea urchin embryogenesis.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Anserine; Antioxidants; Carnosine; Chromosome Aberrations; Deoxyguanosine; Embryo, Nonmammalian; Free Radical Scavengers; Germ Cells; Luminescent Measurements; Methionine; Mitosis; Reactive Oxygen Species; Sea Urchins; Stereoisomerism

1997
Liver intracellular L-cysteine concentration is maintained after inhibition of the trans-sulfuration pathway by propargylglycine in rats.
    The British journal of nutrition, 1997, Volume: 78, Issue:5

    Topics: Acetylcysteine; Alkynes; Animals; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Depression, Chemical; Glutathione; Glycine; Liver; Male; Methionine; Rats; Rats, Wistar; Urea

1997
Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:6

    Topics: Acetylcysteine; Antioxidants; Bronchoalveolar Lavage Fluid; Female; Glutathione; Glutathione Disulfide; Humans; Immunosuppressive Agents; Lung; Male; Methionine; Middle Aged; Oxidative Stress; Prospective Studies; Pulmonary Fibrosis

1997
Paracetamol poisoning.
    Accident and emergency nursing, 1998, Volume: 6, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Emergency Nursing; Free Radical Scavengers; Humans; Methionine

1998
Calnexin association is not sufficient to protect T cell receptor alpha proteins from rapid degradation in CD4+CD8+ thymocytes.
    The Journal of biological chemistry, 1998, Sep-11, Volume: 273, Issue:37

    Topics: Acetylcysteine; Animals; Calcium-Binding Proteins; Calnexin; CD4 Antigens; CD8 Antigens; Cells, Cultured; Cysteine Proteinase Inhibitors; Diamide; Half-Life; Methionine; Mice; Mice, Inbred C57BL; Molecular Chaperones; Receptors, Antigen, T-Cell, alpha-beta; Spleen; Sulfur Radioisotopes; T-Lymphocyte Subsets; T-Lymphocytes; Tosylphenylalanyl Chloromethyl Ketone

1998
Ascorbate and glutathione homeostasis in vascular smooth muscle cells: cooperation with endothelial cells.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Acetylcysteine; Ascorbic Acid; Cells, Cultured; Coculture Techniques; Cystine; Dehydroascorbic Acid; Endothelium, Vascular; Glutathione; Homeostasis; Humans; Kinetics; Methionine; Muscle, Smooth, Vascular; Oxidation-Reduction; Phloretin; Umbilical Veins

1998
N-acetylcysteine enhances endothelium-dependent vasorelaxation in the isolated rat mesenteric artery.
    Annals of emergency medicine, 1998, Volume: 32, Issue:4

    Topics: Acetylcholine; Acetylcysteine; Analysis of Variance; Animals; Calcimycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; In Vitro Techniques; Mesenteric Arteries; Methionine; Rats; Vasodilation; Vasodilator Agents

1998
N-acetylcysteine and anti-ICAM-1 monoclonal antibody reduce ischemia-reperfusion injury of the steatotic rat liver.
    Transplantation proceedings, 1998, Volume: 30, Issue:7

    Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Antibodies, Monoclonal; Choline Deficiency; Fatty Liver; Glutathione; Insulin; Intercellular Adhesion Molecule-1; Ischemia; Liver; Male; Methionine; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Reperfusion Injury

1998
Deaths from low dose paracetamol poisoning. Use of oral methionine for overdose below threshold for acetylcysteine.
    BMJ (Clinical research ed.), 1998, Dec-12, Volume: 317, Issue:7173

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Analgesics, Non-Narcotic; Antidotes; Humans; Methionine

1998
N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain.
    Neuroscience letters, 1999, Jan-08, Volume: 259, Issue:2

    Topics: Acetylcysteine; Animals; Brain; Cells, Cultured; Cysteine; Female; Glutathione; Methionine; Neurons; Pregnancy; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines

1999
Sulfur-containing amino acids decrease cisplatin cytotoxicity and uptake in renal tubule epithelial cell lines.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:1

    Topics: Acetylcysteine; Amino Acids; Animals; Antineoplastic Agents; Cisplatin; Cysteine; Homocysteine; Humans; Kidney Tubules; Methionine; Mice; Tumor Cells, Cultured

2000
Drosophila ACT88F indirect flight muscle-specific actin is not N-terminally acetylated: a mutation in N-terminal processing affects actin function.
    Journal of molecular biology, 2000, Feb-04, Volume: 295, Issue:5

    Topics: Acetylation; Acetylcysteine; Actins; Actomyosin; Animals; Drosophila melanogaster; Electrophoresis, Gel, Two-Dimensional; Flight, Animal; Genes, Insect; Isoelectric Point; Mass Spectrometry; Methionine; Methylation; Methylcellulose; Mutation; Phenotype; Protein Isoforms; Protein Processing, Post-Translational; Viscosity

2000
Severity of overdose after restriction of paracetamol availability. Why hasn't strategy for minimising paracetamol poisoning been enacted?
    BMJ (Clinical research ed.), 2001, Mar-03, Volume: 322, Issue:7285

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Chemistry, Pharmaceutical; Humans; Methionine; Poisoning

2001
Glucose regulates protein catabolism in ras-transformed fibroblasts through a lysosomal-dependent proteolytic pathway.
    The Biochemical journal, 2001, Jul-01, Volume: 357, Issue:Pt 1

    Topics: 3T3 Cells; Acetylcysteine; Animals; Cathepsin B; Cathepsin D; Cathepsin L; Cathepsins; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Fibroblasts; Genes, ras; Glucose; Humans; Kinetics; Kirsten murine sarcoma virus; L-Lactate Dehydrogenase; Lysosomes; Methionine; Methylamines; Mice; Protein Biosynthesis; Proteins; Tumor Cells, Cultured

2001
Induction of apoptosis by chemotherapeutic drugs without generation of reactive oxygen species.
    Archives of biochemistry and biophysics, 2002, Jan-15, Volume: 397, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Burkitt Lymphoma; Cisplatin; Cyclic N-Oxides; Etoposide; F2-Isoprostanes; Humans; Hydrogen Peroxide; Metalloporphyrins; Methionine; Oxidants; Reactive Oxygen Species; Spin Labels

2002
6-Hydroxydopamine increases ubiquitin-conjugates and protein degradation: implications for the pathogenesis of Parkinson's disease.
    Cellular and molecular neurobiology, 2001, Volume: 21, Issue:6

    Topics: Acetylcysteine; Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Leupeptins; Lewy Bodies; Methionine; Models, Neurological; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Oxidopamine; Parkinson Disease; PC12 Cells; Proteasome Endopeptidase Complex; Rats; Substantia Nigra; Sulfur Radioisotopes; Sympatholytics; Ubiquitins

2001
The urinary excretion of mercapturic acids after administration of bromobenzene and 3,4-benzpyrene.
    Cancer research, 1950, Volume: 10, Issue:11

    Topics: Acetylcysteine; Benzo(a)pyrene; Benzopyrenes; Bromobenzenes; Humans; Methionine

1950
A pulsed potential waveform displaying enhanced detection capabilities towards sulfur-containing compounds at a gold working electrode.
    Journal of chromatography. A, 2005, Feb-25, Volume: 1066, Issue:1-2

    Topics: Acetylcysteine; Biotin; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Cystine; Electrochemistry; Electrodes; Glutathione; Gold; Homocysteine; Methionine; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Sulfur Compounds; Thioctic Acid

2005
Comparison of captopril and enalapril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE inhibitors in high dieted methionine mice.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:1

    Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aryldialkylphosphatase; Captopril; Enalapril; Endothelium, Vascular; Male; Malondialdehyde; Methionine; Nitric Oxide; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Superoxide Dismutase; Vasodilation

2006
Metabolism of acrylamide to glycidamide and their cytotoxicity in isolated rat hepatocytes: protective effects of GSH precursors.
    Archives of toxicology, 2006, Volume: 80, Issue:12

    Topics: Acetylcysteine; Acrylamide; Animals; Ascorbic Acid; Biotransformation; Carcinogens; Cell Survival; Cytochrome P-450 CYP2E1; Cytoprotection; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Glutathione Transferase; Hepatocytes; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Methionine; Models, Biological; Protective Agents; Rats; Rats, Sprague-Dawley

2006
Drugs affecting prelamin A processing: effects on heterochromatin organization.
    Experimental cell research, 2008, Feb-01, Volume: 314, Issue:3

    Topics: Acetylcysteine; Adult; Antimetabolites, Antineoplastic; Azacitidine; Cell Nucleus; Cells, Cultured; Chromatin Assembly and Disassembly; Decitabine; DNA-Binding Proteins; Enzyme Inhibitors; Farnesyltranstransferase; Fibroblasts; Heterochromatin; Humans; Lamin Type A; Membrane Proteins; Methionine; Nuclear Lamina; Nuclear Proteins; Protein Precursors; Protein Prenylation

2008
Enhancing glutathione synthesis can decrease zinc-mediated toxicity.
    Biological trace element research, 2008, Volume: 122, Issue:3

    Topics: Acetylcysteine; Cell Line; Cell Line, Tumor; Cysteine; Glutathione; Humans; Hydrocortisone; Methionine; Reducing Agents; Stereoisomerism; Up-Regulation; Zinc Compounds

2008
Selection of agents for prevention of cisplatin-induced hepatotoxicity.
    Pharmacological research, 2008, Volume: 57, Issue:2

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Antineoplastic Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Cisplatin; Drug Therapy, Combination; Fosfomycin; Glutathione; Injections, Intraperitoneal; Male; Malondialdehyde; Methionine; Mice; Pilot Projects; Selenium; Taurine; Thiosulfates; Zinc

2008
Antioxidant effects of methionine, alpha-lipoic acid, N-acetylcysteine and homocysteine on lead-induced oxidative stress to erythrocytes in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 60, Issue:4-5

    Topics: Acetylcysteine; Animals; Antioxidants; Chromatography, High Pressure Liquid; Erythrocytes; Glutathione Peroxidase; Hemoglobins; Homocystine; Lead; Male; Malondialdehyde; Methionine; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid; Vitamin A; Vitamin E

2008
Effects of prelamin A processing inhibitors on the differentiation and activity of human osteoclasts.
    Journal of cellular biochemistry, 2008, Sep-01, Volume: 105, Issue:1

    Topics: Acetylcysteine; Biomarkers; Cell Differentiation; Cells, Cultured; Humans; Lamin Type A; Methionine; Nuclear Proteins; Osteoclasts; Protein Precursors

2008
Global DNA hypomethylation, rather than reactive oxygen species (ROS), a potential facilitator of cadmium-stimulated K562 cell proliferation.
    Toxicology letters, 2008, Jun-10, Volume: 179, Issue:1

    Topics: Acetylcysteine; Cadmium Chloride; Carcinogens; Cell Line, Tumor; Cell Proliferation; Comet Assay; DNA Damage; DNA Methylation; DNA, Neoplasm; Drug Combinations; Epigenesis, Genetic; Free Radical Scavengers; Gene Silencing; Humans; K562 Cells; Methionine; Reactive Oxygen Species

2008
[Determination of the N-acetylcysteine and methionine effects in the cerebellum of rats intoxicated with lead].
    Investigacion clinica, 2008, Volume: 49, Issue:1

    Topics: Acetylcysteine; Animals; Cerebellum; Lead; Lead Poisoning; Male; Methionine; Rats; Rats, Wistar

2008
H2S protects against methionine-induced oxidative stress in brain endothelial cells.
    Antioxidants & redox signaling, 2009, Volume: 11, Issue:1

    Topics: Acetophenones; Acetylcysteine; Animals; Brain; Catalase; Cell Line, Transformed; Cell Survival; Dose-Response Relationship, Drug; Endothelial Cells; Formazans; Glutathione; Homocysteine; Hydrogen Sulfide; Methionine; Mice; Models, Biological; NG-Nitroarginine Methyl Ester; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Time Factors

2009
Management of acute paracetamol poisoning in a tertiary care hospital.
    The Ceylon medical journal, 2008, Volume: 53, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Acute Disease; Analgesics, Non-Narcotic; Antidotes; Charcoal; Emetics; Evidence-Based Medicine; Female; Hospitals, Public; Humans; Male; Methionine; Poisoning; Sodium Bicarbonate; Sri Lanka; Time Factors; Treatment Outcome; Young Adult

2008
Cost of the paracetamol overdose epidemic.
    The Ceylon medical journal, 2010, Volume: 55, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Drug Overdose; Humans; Methionine; Sri Lanka; Suicide

2010
Premature senescence of vascular cells is induced by HIV protease inhibitors: implication of prelamin A and reversion by statin.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:12

    Topics: Acetylcysteine; Adult; Antioxidants; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cellular Senescence; Coronary Vessels; Cyclin-Dependent Kinase Inhibitor p21; Drug Therapy, Combination; Endothelial Cells; Farnesyltranstransferase; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lamin Type A; Lopinavir; Metalloporphyrins; Methionine; Middle Aged; Nuclear Proteins; Oxidative Stress; Paris; Pravastatin; Protein Precursors; Pyrimidinones; Ritonavir; Time Factors; Tumor Suppressor Protein p53

2010
Enhancement of gallic acid-induced human pulmonary fibroblast cell death by N-acetyl cysteine and L-buthionine sulfoximine.
    Human & experimental toxicology, 2011, Volume: 30, Issue:8

    Topics: Acetylcysteine; Anticarcinogenic Agents; Cell Culture Techniques; Cell Death; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Gallic Acid; Glutathione; Humans; Lung; Membrane Potential, Mitochondrial; Methionine; Reactive Oxygen Species

2011
Low-dose D-methionine and N-acetyl-L-cysteine for protection from permanent noise-induced hearing loss in chinchillas.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2011, Volume: 145, Issue:6

    Topics: Acetylcysteine; Animals; Auditory Threshold; Chinchilla; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Female; Hearing Loss, Noise-Induced; Injections, Intraperitoneal; Methionine; Random Allocation; Reference Values; Treatment Outcome

2011
Dose-dependent protection on cisplatin-induced ototoxicity - an electrophysiological study on the effect of three antioxidants in the Sprague-Dawley rat animal model.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:8

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Auditory Threshold; Azoles; Cisplatin; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory, Outer; Isoindoles; Male; Methionine; Models, Animal; Organoselenium Compounds; Otoacoustic Emissions, Spontaneous; Rats; Rats, Sprague-Dawley

2011
A cost effectiveness analysis of the preferred antidotes for acute paracetamol poisoning patients in Sri Lanka.
    BMC clinical pharmacology, 2012, Feb-22, Volume: 12

    Topics: Acetaminophen; Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Chemical and Drug Induced Liver Injury; Cost-Benefit Analysis; Decision Trees; Humans; Methionine; Sri Lanka; Time Factors

2012
Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:4

    Topics: Acetylcysteine; Adiposity; Amino Acids; Amino Acids, Sulfur; Animals; Cysteine; Diet; Fatty Acids, Nonesterified; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Lipids; Male; Methionine; Rats; Rats, Inbred F344; Stearoyl-CoA Desaturase; Taurine; Weight Gain

2013
The metabolic function of hepatocytes differentiated from human mesenchymal stem cells is inversely related to cellular glutathione levels.
    Cell biochemistry and function, 2014, Volume: 32, Issue:2

    Topics: Acetylcysteine; Cell Differentiation; Cell Line; Glutathione; Hepatocytes; Humans; Mesenchymal Stem Cells; Methionine; Reactive Oxygen Species; Sulfoxides

2014
[Au(dien)(N-heterocycle)](3+): reactivity with biomolecules and zinc finger peptides.
    Inorganic chemistry, 2015, Jan-05, Volume: 54, Issue:1

    Topics: 4-Aminopyridine; Acetylcysteine; Animals; Cattle; Coordination Complexes; DNA; Ethidium; Fluorescence; Gold; Heterocyclic Compounds; Ligands; Methionine; Peptides; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Zinc; Zinc Fingers

2015
Comparative effects of sulfhydryl compounds on target organellae, nuclei and mitochondria, of hydroxylated fullerene-induced cytotoxicity in isolated rat hepatocytes.
    Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:12

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Cell Culture Techniques; Cell Nucleus; Cell Survival; Cells, Cultured; Cysteine; DNA Damage; Fullerenes; Hepatocytes; Male; Membrane Potential, Mitochondrial; Methionine; Organelles; Rats, Inbred F344; Reactive Oxygen Species; Sulfhydryl Compounds

2015
Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats.
    Pharmaceutical biology, 2016, Volume: 54, Issue:7

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Choline Deficiency; Cytoprotection; Disease Models, Animal; Hypolipidemic Agents; Lipids; Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Ursodeoxycholic Acid

2016
Comparative study of the oxidation behavior of sulfur-containing amino acids and glutathione by electrochemistry-mass spectrometry in the presence and absence of cisplatin.
    Analytical and bioanalytical chemistry, 2016, Volume: 408, Issue:4

    Topics: Acetylcysteine; Amino Acids; Cisplatin; Electrochemistry; Glutathione; Mass Spectrometry; Methionine; Oxidation-Reduction; Sulfhydryl Compounds; Sulfur

2016
Treatments for paracetamol poisoning.
    BMJ (Clinical research ed.), 2016, May-18, Volume: 353

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Drug Overdose; Female; Humans; Methionine; Time Factors; Young Adult

2016
Suppression of methionine-induced colon injury of young rats by cysteine and N-acetyl-L-cysteine.
    Molecular and cellular biochemistry, 2018, Volume: 440, Issue:1-2

    Topics: Acetylcysteine; Animals; Colon; Colonic Diseases; Male; Methionine; Rats; Rats, Wistar

2018
Improving the safety of metal-based drugs by tuning their metabolism with chemoprotective agents.
    Journal of inorganic biochemistry, 2018, Volume: 179

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cisplatin; Glutathione; Humans; Methionine; Protective Agents; Sulfur Compounds; Thiosulfates

2018
Subchronic methionine load induces oxidative stress and provokes biochemical and histological changes in the rat liver tissue.
    Molecular and cellular biochemistry, 2018, Volume: 448, Issue:1-2

    Topics: Acetylcysteine; Animals; Glutathione; Hepatocytes; Liver; Macrophages; Male; Malondialdehyde; Methionine; Necrosis; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar

2018
Response to medical and a novel dietary treatment in newborn screen identified patients with ethylmalonic encephalopathy.
    Molecular genetics and metabolism, 2018, Volume: 124, Issue:1

    Topics: Acetylcysteine; Amino Acids; Biomarkers; Brain Diseases, Metabolic, Inborn; Cysteine; Diet; Female; Humans; Infant; Infant, Newborn; Lactic Acid; Male; Malonates; Methionine; Metronidazole; Mitochondrial Proteins; Mutation; Neonatal Screening; Nucleocytoplasmic Transport Proteins; Purpura; Sulfur

2018
The effects of L-cysteine and N-acetyl-L-cysteine on homocysteine metabolism and haemostatic markers, and on cardiac and aortic histology in subchronically methionine-treated Wistar male rats.
    Molecular and cellular biochemistry, 2019, Volume: 451, Issue:1-2

    Topics: Acetylcysteine; Animals; Aorta; Biomarkers; Cysteine; Heart; Hemostatics; Homocysteine; Male; Methionine; Rats; Rats, Wistar

2019
Copper nanoclusters electrochemiluminescence with tunable near-infrared emission wavelength for ultrasensitive detection of matrix metalloproteinase-2.
    Biosensors & bioelectronics, 2023, Oct-15, Volume: 238

    Topics: Acetylcysteine; Biosensing Techniques; Copper; Humans; Matrix Metalloproteinase 2; Methionine; Racemethionine

2023