methimazole and benzamidine

methimazole has been researched along with benzamidine* in 1 studies

Other Studies

1 other study(ies) available for methimazole and benzamidine

ArticleYear
An improved approach to the analysis of drug-protein binding by distance geometry.
    Journal of molecular structure, 1986, Volume: 134

    The calculation of side chain centers of coordinates and the subsequent generation of side chain-side chain and side chain-backbone distance matrices is suggested as an improved method for viewing interactions inside proteins and for the comparison of protein structures. The use of side chain distance matrices is demonstrated with free PTI, and the use of difference distance matrices for side chains is shown for free and trypsin-bound PTI as well as for the X-ray structures of trypsin complexes with PTI and with benzamidine. It is found that conformational variations are reflected in the side chain distance matrices much more than in the standard C-C distance representations.

    Topics: Benzamidines; Chemistry, Pharmaceutical; Methimazole; Models, Molecular; Molecular Structure; Protein Binding; Proteins; Receptors, Drug; Trypsin

1986