methimazole and 3-4-5-3--4--pentachlorobiphenyl

methimazole has been researched along with 3-4-5-3--4--pentachlorobiphenyl* in 1 studies

Other Studies

1 other study(ies) available for methimazole and 3-4-5-3--4--pentachlorobiphenyl

Article	Year
Effects of oral exposure to polychlorinated biphenyls (PCBs) on the development and metamorphosis of two amphibian species (Xenopus laevis and Rana temporaria). The Science of the total environment, 2000, Oct-30, Volume: 262, Issue:1-2 This study examined the effects of polychlorinated biphenyls (PCBs) on development of families of amphibians using the African clawed frog (Xenopus laevis) and the European common frog (Rana temporaria). Amphibians were orally exposed to the technical PCB-mixture Clophen A50 or to the non-ortho-3,3',4,4',5-CB congener (PCB 126) either for a 10-day period or until metamorphosis. Occurrence and rate of malformations, mortality, period until metamorphosis and thyroid hormone levels were measured. Mortality increased in a dose-dependent manner, as did the rates of malformation. Time until metamorphic transformation was prolonged and the weight of froglets was increased. Although not statistically significant, thyroid hormone levels were also lowered. PHAHs such as PCBs may affect important aspects of amphibian fitness and may influence amphibian reproductive success. Topics: Administration, Oral; Animals; Antithyroid Agents; Body Weight; Environmental Pollutants; Imidazoles; Larva; Metamorphosis, Biological; Mortality; Polychlorinated Biphenyls; Rana temporaria; Thyroid Hormones; Xenopus laevis	2000

Article

Year

Effects of oral exposure to polychlorinated biphenyls (PCBs) on the development and metamorphosis of two amphibian species (Xenopus laevis and Rana temporaria).

The Science of the total environment, 2000, Oct-30, Volume: 262, Issue:1-2

This study examined the effects of polychlorinated biphenyls (PCBs) on development of families of amphibians using the African clawed frog (Xenopus laevis) and the European common frog (Rana temporaria). Amphibians were orally exposed to the technical PCB-mixture Clophen A50 or to the non-ortho-3,3',4,4',5-CB congener (PCB 126) either for a 10-day period or until metamorphosis. Occurrence and rate of malformations, mortality, period until metamorphosis and thyroid hormone levels were measured. Mortality increased in a dose-dependent manner, as did the rates of malformation. Time until metamorphic transformation was prolonged and the weight of froglets was increased. Although not statistically significant, thyroid hormone levels were also lowered. PHAHs such as PCBs may affect important aspects of amphibian fitness and may influence amphibian reproductive success.

Topics: Administration, Oral; Animals; Antithyroid Agents; Body Weight; Environmental Pollutants; Imidazoles; Larva; Metamorphosis, Biological; Mortality; Polychlorinated Biphenyls; Rana temporaria; Thyroid Hormones; Xenopus laevis

2000