Page last updated: 2024-08-17

methaqualone and phenobarbital

methaqualone has been researched along with phenobarbital in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199038 (90.48)18.7374
1990's3 (7.14)18.2507
2000's0 (0.00)29.6817
2010's1 (2.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, JA; Greenwood, TD; Rathman, TL; Sleevi, MC; Wolfe, JF1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brunner, G; Harstick, K; Holloway, CJ; Külpmann, WR; Petry, K1
Mohrbacher, RJ; Riendeau, CJ; Werner, M1
Naid, PR; Naik, SR; Sheth, UK1
O'Connor, MF; Piepho, RW; Reinke, LA; Stohs, SJ1
Ho, AK; Ho, CC2
Reavey, PC; Tilstone, WJ1
Mathur, PP; Procaccini, RL; Reavey-Cantwell, NH; Smyth, RD1
Dalal, F; Kramer, MS; Raja, R; Rosenbaum, JL; Winsten, S1
Batt, AM; Khodjet el Khil, R; Siest, G; Tridon, P; Weber, M1
Udall, JA1
Boren, JA; Mathur, PP; Reavey-Cantwell, NH; Smyth, RD1
Herczeg, T; Mathur, PP; Reavey-Cantwell, NH; Smyth, RD1
Manowitz, P; Shull, CM1
Demme, U; Feistel, L; Günther, K; Junge, W; Kehnscherper, R; Schwachula, G; Stein, G; Werner, R1
Patrick, GA; Rosenberger, W; Yutrzenka, GJ1
Regestein, QR1
Balazs, T; Tocus, EC; Yen-Koo, HC1
Gomez, J; Rodriguez, A1
Brown, DB; Fortenberry, JC; Shevlin, LT1
Browne, R; Possley, L; Zaroslinski, J1
Bailey, DN; Jatlow, PI1
Marcy, R; Quermonne, MA1
Freiberg, J; Grosser, KD; Kunst, H; Sieberth, HG; von Baeyer, H1
Tölle, R1
Haider, I; Oswald, I1
Oswald, I1
Kempfle, B; Reschke, L; Schmidtmann, W1
Hoffmeister, F1
Clifford, JM; Cookson, JH; Wickham, PE1
Flanagan, RJ; Withers, G1
Kourounakis, P; Selye, H; Szabo, S1
Kohli, RP; Kulshrestha, VK; Singh, N1
Hatch, RC1
Kondo, M1
Banez, RJ; Combs, HF; Decker, WJ; Treuting, JJ1
Ewart, RB; Priest, RG1
Globus, M; McColl, JD; Robinson, S1
Garibova, TL; Voronina, TA1
VELGHE, R1

Trials

2 trial(s) available for methaqualone and phenobarbital

ArticleYear
Psychoactive drugs and sleep: withdrawal rebound phenomena.
    Triangle; the Sandoz journal of medical science, 1971, Volume: 10, Issue:3

    Topics: Benzazepines; Clinical Trials as Topic; Humans; Methaqualone; Nerve Tissue Proteins; Phenobarbital; Sleep, REM; Substance Withdrawal Syndrome

1971
Absorption and clearance of secobarbital, heptabarbital, methaqualone, and ethinamate.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2

    Topics: Adult; Alkynes; Barbiturates; Carbamates; Chromatography, Gas; Clinical Trials as Topic; Cycloheptanes; Cyclohexanes; Half-Life; Humans; Hypnotics and Sedatives; Intestinal Absorption; Male; Methaqualone; Phenobarbital; Quinazolines; Regression Analysis; Secobarbital; Time Factors

1974

Other Studies

40 other study(ies) available for methaqualone and phenobarbital

ArticleYear
Synthesis and anticonvulsant activity of some new 2-substituted 3-aryl-4(3H)-quinazolinones.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Anticonvulsants; Bicuculline; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Electroshock; Lethal Dose 50; Male; Methaqualone; Mice; Molecular Structure; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine

1990
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The removal of hypnotic drugs from human serum. A comparative investigation of the adsorptive properties of native and agarose-encapsulated resins and charcoal.
    The International journal of artificial organs, 1979, Volume: 2, Issue:2

    Topics: Adsorption; Biocompatible Materials; Capsules; Charcoal; Glutethimide; Hemoperfusion; Humans; Hypnotics and Sedatives; Ion Exchange Resins; Mathematics; Methaqualone; Phenobarbital; Polysaccharides; Sepharose; Urea

1979
Gas-liquid chromatography of undervatized drugs after chromatographic extraction from blood.
    Clinical chemistry, 1979, Volume: 25, Issue:12

    Topics: Amobarbital; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Chromatography, Gas; Gastric Juice; Glutethimide; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; Phenytoin; Piperidones; Primidone; Secobarbital

1979
Involvement of gamma-amino butyric acid (GABA) in the anticonvulsant action of methaqualone.
    Psychopharmacology, 1978, Apr-14, Volume: 57, Issue:1

    Topics: Aminobutyrates; Animals; Anticonvulsants; Brain Chemistry; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Methaqualone; Muscle Relaxation; Phenobarbital; Rats; Seizures

1978
A comparison of the inductive effects of phenobarbital, methaqualone, and methyprylon on hepatic mixed function oxidase enzymes in the rat.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 11, Issue:1

    Topics: Animals; Enzyme Induction; Liver; Male; Methaqualone; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phenobarbital; Piperidones; Proteins; Rats

1975
Toxic interactions of ethanol with other central depressants: antagonism by naloxone to narcosis and lethality.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:1

    Topics: Animals; Central Nervous System Depressants; Drug Interactions; Ethanol; Lethal Dose 50; Lithium; Male; Methaqualone; Mice; Naloxone; Phenobarbital; Sleep

1979
Interaction of ethanol with amylobarbitone, phenobarbitone and methaqualone.
    Research communications in chemical pathology and pharmacology, 1978, Volume: 19, Issue:2

    Topics: Amobarbital; Animals; Drug Interactions; Ethanol; Hypnotics and Sedatives; Male; Methaqualone; Phenobarbital; Rats; Time Factors

1978
Comparative effect of phenobarbital and methaqualone on warfarin metabolism in the rat.
    Biochemical pharmacology, 1976, Feb-15, Volume: 25, Issue:4

    Topics: Animals; Enzyme Induction; Male; Methaqualone; Microsomes, Liver; Phenobarbital; Rats; Warfarin

1976
Hemoperfusion for acute drug intoxication.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Adsorption; Adult; Ethchlorvynol; Glutethimide; Humans; Male; Methaqualone; Phenobarbital; Poisoning; Renal Dialysis; Resins, Synthetic

1976
Method for diphenylhydantoin and phenobarbital assay by gas chromatography.
    Pathologie-biologie, 1975, Volume: 23, Issue:5

    Topics: Buffers; Chloroform; Chromatography, Gas; Chromatography, Thin Layer; Colorimetry; Epilepsy; Humans; Methaqualone; Phenobarbital; Phenytoin

1975
Clinical implications of warfarin interactions with five sedatives.
    The American journal of cardiology, 1975, Volume: 35, Issue:1

    Topics: Administration, Oral; Adult; Aged; Blood Coagulation; Chloral Hydrate; Drug Interactions; Glutethimide; Humans; Male; Methaqualone; Middle Aged; Phenobarbital; Prothrombin Time; Secobarbital; Warfarin

1975
Age differences affecting induction of hepatic drug metabolizing enzymes by methaqualone and phenobarbital in the rat.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 11, Issue:1

    Topics: Age Factors; Animals; Enzyme Induction; Hexobarbital; Liver; Male; Methaqualone; Organ Size; Phenobarbital; Rats; Sleep; Time Factors

1975
Induction of hepatic enzymes by methaqualone and effect on warfarin-induced hypoprothrombinemia.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 196, Issue:1

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Enzyme Induction; Hexobarbital; Hypoprothrombinemias; Liver; Male; Methaqualone; Phenobarbital; Proadifen; Prothrombin Time; Rats; Sleep; Time Factors; Warfarin

1976
Methaqualone metabolism by rat liver microsomes.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 13, Issue:1

    Topics: Animals; Chromatography, Gas; Chromatography, Thin Layer; Hydrolysis; Male; Methaqualone; Microsomes, Liver; Phenobarbital; Rats

1976
[In vitro studies of the adsorption behavior of Wofatit Y 88 in relation to various drugs].
    Zeitschrift fur Urologie und Nephrologie, 1990, Volume: 83, Issue:11

    Topics: Adsorption; Barbiturates; Blood Flow Velocity; Hemoperfusion; Humans; Hypnotics and Sedatives; Metabolic Clearance Rate; Methaqualone; Phenobarbital; Polystyrenes; Pyridones

1990
Substitution of psychoactive drugs in pentobarbital-dependent rats.
    Drug and alcohol dependence, 1990, Volume: 26, Issue:1

    Topics: Animals; Antidepressive Agents; Arousal; Body Weight; Brain; Bromazepam; Bupropion; Diazepam; Dose-Response Relationship, Drug; Male; Mazindol; Methaqualone; Motor Activity; Nortriptyline; Phenobarbital; Propiophenones; Psychotropic Drugs; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders

1990
Specific effects of sedative/hypnotic drugs in the treatment of incapacitating chronic insomnia.
    The American journal of medicine, 1987, Volume: 83, Issue:5

    Topics: Adult; Aged; Diazepam; Female; Humans; Hydromorphone; Hypnotics and Sedatives; Male; Methaqualone; Phenobarbital; Sleep Initiation and Maintenance Disorders

1987
The effects of chronic treatment and withdrawal of CNS depressants on aggressive behavior.
    Toxicology and industrial health, 1989, Volume: 5, Issue:6

    Topics: Aggression; Animals; Behavior, Animal; Chlordiazepoxide; Dose-Response Relationship, Drug; Dronabinol; Male; Methaqualone; Mice; Morphine; Phenobarbital; Substance Withdrawal Syndrome; Trifluoperazine

1989
An evaluation of the results of a drug sample analysis.
    Bulletin on narcotics, 1989, Volume: 41, Issue:1-2

    Topics: Amphetamines; Caffeine; Cocaine; Drug Contamination; Heroin; Humans; Illicit Drugs; Lidocaine; Methaqualone; Phenobarbital; Procaine; Spain; Substance-Related Disorders

1989
Analysis of drug involvement in traffic fatalities in Alabama.
    The American journal of drug and alcohol abuse, 1986, Volume: 12, Issue:3

    Topics: Accidents, Traffic; Alabama; Cannabinoids; Dextropropoxyphene; Diazepam; Ethanol; Humans; Methaqualone; Phenobarbital; Substance-Related Disorders

1986
Effect of subacute administration of methaqualone, phenobarbital and glutethimide on plasma levels of bishydroxycoumarin.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 195, Issue:1

    Topics: Administration, Oral; Animals; Depression, Chemical; Dicumarol; Enzyme Induction; Glutethimide; Injections, Intraperitoneal; Male; Methaqualone; Microsomes; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors

1972
Methaqualone overdose: analytical methodology, and the significance of serum drug concentrations.
    Clinical chemistry, 1973, Volume: 19, Issue:6

    Topics: Alcohol Drinking; Alkanes; Chloroform; Chromatography, Gas; Chromatography, Thin Layer; Consciousness; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Histamine H1 Antagonists; Humans; Methadone; Methaqualone; Phenobarbital; Salicylamides; Scopolamine; Solubility; Spectrophotometry, Ultraviolet; Substance-Related Disorders

1973
An improved method for studying the psychogalvanic reaction in mice and its inhibition by psycholeptic drugs. Comparison with the effects of other pharmacological agents.
    Psychopharmacologia, 1974, Feb-06, Volume: 34, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Benactyzine; Chlordiazepoxide; Chlorpromazine; Diazepam; Female; Galvanic Skin Response; Haloperidol; Hydroxyzine; Hypnotics and Sedatives; Male; Meprobamate; Methaqualone; Methotrimeprazine; Mice; Muscle Relaxants, Central; Neuromuscular Nondepolarizing Agents; Nitrazepam; Parasympatholytics; Pentobarbital; Phenobarbital; Phenothiazines; Thioridazine; Tranquilizing Agents; Trifluperidol

1974
[Haemodialysis in intoxication with hypnotics (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Feb-01, Volume: 99, Issue:5

    Topics: Acute Kidney Injury; Adult; Barbiturates; Blood Pressure; Bromides; Diuresis; Diuretics; Electroencephalography; Female; Glutethimide; Humans; Hypnotics and Sedatives; Male; Meprobamate; Metabolic Clearance Rate; Methaqualone; Middle Aged; Phenobarbital; Phenothiazines; Piperidones; Poisoning; Renal Dialysis; Suicide; Time Factors

1974
[Unexpected complications by anticholinergics contained in hypnotics and analgesics].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:8

    Topics: Adult; Analgesics; Benactyzine; Codeine; Diphenhydramine; Drug Combinations; Female; Humans; Hypnotics and Sedatives; Male; Methaqualone; Parasympatholytics; Phenacetin; Phenobarbital; Psychoses, Substance-Induced; Salicylamides; Urea

1974
Late brain recovery processes after drug overdose.
    British medical journal, 1970, May-09, Volume: 2, Issue:5705

    Topics: Adult; Benzazepines; Brain; Delirium; Drug Tolerance; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Methaqualone; Middle Aged; Phenobarbital; Poisoning; Sleep Initiation and Maintenance Disorders; Sleep, REM; Substance Withdrawal Syndrome; Substance-Related Disorders; Unconsciousness

1970
[A spray reagent combination for differential determination of methyprylon from its main metabolite methylpersedon as well as a selection of hypnotics and eukraton on thin layer chromatograms].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Barbiturates; Bemegride; Chromatography, Thin Layer; Glutethimide; Hexobarbital; Hypnotics and Sedatives; Indicators and Reagents; Methaqualone; Phenobarbital; Piperidines; Urea

1969
[Electroencephalogram and behavior of rabbits in physiological and drug-induced sleep. 3. Influence of hypnotics on sleeping behavior of rabbits; discussion and summary].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:3

    Topics: Animals; Barbiturates; Behavior, Animal; Circadian Rhythm; Cyclohexanes; Diazepam; Electroencephalography; Hypnotics and Sedatives; Methaqualone; Motor Activity; Nitrazepam; Periodicity; Phenobarbital; Piperidones; Promethazine; Rabbits; Sleep; Sleep Stages; Sleep, REM; Urea

1972
A rapid micro-method for the screening and measurement of barbiturates and related compounds in plasma by gas-liquid chromatography.
    Journal of clinical pathology, 1972, Volume: 25, Issue:10

    Topics: Amobarbital; Animals; Barbiturates; Blood Specimen Collection; Cattle; Chromatography, Gas; Evaluation Studies as Topic; Glutethimide; Hexobarbital; Humans; Methaqualone; Methods; Microchemistry; Pentobarbital; Phenobarbital; Secobarbital; Time Factors

1972
Protection by catatoxic steroids, phenobarbital and diphenylhydantoin against methaqualone intoxication.
    Steroids and lipids research, 1972, Volume: 3, Issue:2

    Topics: Androstenes; Animals; Enzyme Induction; Ethylestrenol; Female; Hydroxysteroids; Ketosteroids; Methaqualone; Movement Disorders; Nitriles; Norsteroids; Oxandrolone; Phenobarbital; Phenytoin; Pregnenolone; Propionates; Rats; Spironolactone; Steroids

1972
An experimental investigation of dependence liability of methaqualone in rats.
    Psychopharmacologia, 1974, Mar-09, Volume: 35, Issue:4

    Topics: Acoustic Stimulation; Animals; Body Temperature; Body Weight; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Male; Methaqualone; Motor Activity; Phenobarbital; Rats; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1974
Simultaneous identification and quantitation of submicrogram amounts of barbiturates by gas chromatography.
    American journal of veterinary research, 1972, Volume: 33, Issue:1

    Topics: Barbiturates; Chromatography, Gas; Hexobarbital; Methaqualone; Methods; Methohexital; Pentobarbital; Phenobarbital; Thiamylal; Thiopental

1972
Isolation and identification of hypnotics. 9. Simultaneous identification of hypnotics and alcohols.
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1972, Volume: 26, Issue:1

    Topics: 1-Propanol; Alcohols; Alkynes; Animals; Carbamates; Chromatography, Thin Layer; Cyclohexanes; Ethanol; Hypnotics and Sedatives; Methanol; Methaqualone; Phenobarbital; Rabbits; Urea; Valerates

1972
Dialysis of drugs against activated charcoal.
    Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3

    Topics: Adsorption; Amitriptyline; Aspirin; Charcoal; Chlordiazepoxide; Chloroquine; Dextroamphetamine; Dextropropoxyphene; Dialysis; Diazepam; Glutethimide; Meprobamate; Methaqualone; Models, Biological; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Salicylates; Secobarbital; Time Factors

1971
Methaqualone addiction and delirium tremens.
    British medical journal, 1967, Jul-08, Volume: 3, Issue:5557

    Topics: Humans; Male; Methaqualone; Middle Aged; Paraldehyde; Phenobarbital; Promazine; Psychoses, Alcoholic; Substance Withdrawal Syndrome; Substance-Related Disorders; Thioridazine; Tranquilizing Agents

1967
Effect of some therapeutic agents on the rabbit fetus.
    Toxicology and applied pharmacology, 1967, Volume: 10, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Aspirin; Dimenhydrinate; Female; Fetus; Glutethimide; Methaqualone; Phenobarbital; Rabbits; Thalidomide; Tolbutamide; Tranquilizing Agents; Uterus

1967
Ethanol-sedative hypnotic interactions: in vitro studies on Na-K-activated adenosine triphosphatase.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 248, Issue:1

    Topics: Animals; Disulfiram; Drug Interactions; Ethanol; Hypnotics and Sedatives; In Vitro Techniques; Kinetics; Male; Methaqualone; Microsomes; Phenobarbital; Pyrazoles; Rats; Sodium-Potassium-Exchanging ATPase

1980
[Experimental study of the "'rebound syndrome" following discontinuation of prolonged phenazepam administration and possibilities for preventing it].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlorpromazine; Conditioning, Classical; Depression; Diazepam; Humans; Male; Meprobamate; Methaqualone; Morpholines; Phenobarbital; Rats; Substance Withdrawal Syndrome

1981
[CONTROLLED CLINICAL TRIAL OF A SLEEP INDUCER].
    Bruxelles medical, 1963, Nov-24, Volume: 43

    Topics: Amobarbital; Barbiturates; Geriatrics; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; Placebos; Sleep; Sleep Initiation and Maintenance Disorders

1963