methapyrilene has been researched along with phenobarbital in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Albertini, S; Gocke, E | 2 |
| Kovatch, RM; Lijinsky, W; Thomas, BJ | 1 |
| Glauert, HP; Pitot, HC | 1 |
| Kammerer, RC; Lampe, MA | 1 |
| Furuya, K; Mori, H; Williams, GM | 1 |
| Hayashi, H; Kanki, M; Minami, K; Mitsumori, K; Morikawa, Y; Omura, K; Ono, A; Uehara, T; Urushidani, T; Yamada, H | 1 |
10 other study(ies) available for methapyrilene and phenobarbital
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Phenobarbital: does the positive result in TA1535 indicate genotoxic properties?
Topics: Animals; Antimutagenic Agents; DNA, Bacterial; Drug Synergism; Liver Extracts; Male; Methapyrilene; Mutagenicity Tests; Mutagens; Phenobarbital; Rats; Salmonella typhimurium; Species Specificity; Time Factors | 1992 |
The carcinogenic effect of methapyrilene combined with nitrosodiethylamine given to rats in low doses.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Diethylnitrosamine; Drug Interactions; Female; Hepatectomy; Leukemia, Experimental; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Methapyrilene; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred F344 | 1992 |
Effect of the antihistamine, methapyrilene, as an initiator of hepatocarcinogenesis in female rats.
Topics: Adenosine Triphosphatases; Aminopyridines; Animals; Female; gamma-Glutamyltransferase; Glucose-6-Phosphatase; Hepatectomy; Histocytochemistry; Liver Neoplasms, Experimental; Methapyrilene; Phenobarbital; Phenotype; Rats; Rats, Inbred F344 | 1989 |
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole | 1987 |
An enhancing effect of the antihistaminic drug methapyrilene on rat liver carcinogenesis by previously administered N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Aminopyridines; Animals; Liver Neoplasms, Experimental; Male; Methapyrilene; Phenobarbital; Rats; Rats, Inbred F344 | 1983 |
Synergistic/comutagenic action in the Ames test as an indication of irrelevant positive findings.
Topics: Anthracenes; Anti-Bacterial Agents; Azides; Carcinogens; DNA Damage; Drug Synergism; False Positive Reactions; Histidine; Methapyrilene; Molecular Structure; Mutagenesis; Mutagenicity Tests; Mutagens; Phenobarbital; Salmonella typhimurium; Sodium Azide | 1996 |
Detection of initiating potential of non-genotoxic carcinogens in a two-stage hepatocarcinogenesis study in rats.
Topics: Acetaminophen; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Glutathione Transferase; Liver Neoplasms; Male; Methapyrilene; Mutagenicity Tests; Oxidative Stress; Phenobarbital; Rats, Sprague-Dawley; Thioacetamide | 2014 |