Compounds > methapyrilene

methapyrilene and acetaminophen

methapyrilene has been researched along with acetaminophen in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (30.00)	29.6817
2010's	7 (70.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chang, EK; Hexdall, AH; Hoffman, RS; Nelson, LS; Sharma, AN	1
Hayashi, H; Kanki, M; Minami, K; Mitsumori, K; Morikawa, Y; Omura, K; Ono, A; Uehara, T; Urushidani, T; Yamada, H	1
Berckmans, P; Covaci, A; Hollanders, K; Maho, W; Peers, B; Remy, S; Verstraelen, S; Witters, H	1

Other Studies

10 other study(ies) available for methapyrilene and acetaminophen

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Diphenhydramine-induced wide complex dysrhythmia responds to treatment with sodium bicarbonate. The American journal of emergency medicine, 2003, Volume: 21, Issue:3 Topics: Acetaminophen; Adult; Arrhythmias, Cardiac; Aspirin; Diphenhydramine; Drug Combinations; Fatal Outcome; Female; Humans; Hypertonic Solutions; Hypnotics and Sedatives; Infusions, Intravenous; Male; Methapyrilene; Nonprescription Drugs; Salicylamides; Sodium Bicarbonate; Suicide, Attempted; Treatment Outcome	2003
Detection of initiating potential of non-genotoxic carcinogens in a two-stage hepatocarcinogenesis study in rats. The Journal of toxicological sciences, 2014, Volume: 39, Issue:5 Topics: Acetaminophen; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Glutathione Transferase; Liver Neoplasms; Male; Methapyrilene; Mutagenicity Tests; Oxidative Stress; Phenobarbital; Rats, Sprague-Dawley; Thioacetamide	2014
Phenotypic and biomarker evaluation of zebrafish larvae as an alternative model to predict mammalian hepatotoxicity. Journal of applied toxicology : JAT, 2016, Volume: 36, Issue:9 Topics: Acetaminophen; Amiodarone; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Ceruloplasmin; Coumarins; Female; Gene Expression Regulation; Genetic Markers; Genome-Wide Association Study; Humans; In Situ Hybridization; Larva; Liver; Male; Methapyrilene; Nitriles; Oxidoreductases, N-Demethylating; Phenotype; Toxicity Tests; Transferrin; Triazoles; Zebrafish; Zebrafish Proteins	2016