methamphetamine has been researched along with piperidines in 100 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (21.00) | 18.7374 |
| 1990's | 16 (16.00) | 18.2507 |
| 2000's | 24 (24.00) | 29.6817 |
| 2010's | 32 (32.00) | 24.3611 |
| 2020's | 7 (7.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishida, R; Ito, K; Kowa, Y; Nurimoto, S; Shintomi, K; Yamamura, M | 1 |
| Ishida, R; Nakamura, S; Sugihara, J | 1 |
| Akiyama, K; Okumura, K; Otsuki, S; Ujike, H; Zushi, Y | 1 |
| Cler, JA; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 2 |
| Heikkila, RE; Riordan, DE; Sonsalla, PK | 1 |
| Cler, JA; Contreras, PC; Dilworth, VM; Emmett, MR; Gray, NM; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Hayakawa, K; Imaizumi, N; Ishikura, H; Kobayashi, H; Minogawa, E; Miyazaki, M; Takayama, N | 1 |
| Gibb, JW; Hanson, GR; Johnson, M | 1 |
| Ohno, M; Takao, K; Ueki, S; Yamamoto, T | 1 |
| Kimishima, K; Ogura, C | 1 |
| Kelfer, DA; Rosen, AJ | 1 |
| Jurna, I | 2 |
| Jurna, I; Regélhy, B | 1 |
| Jurna, I; Lanzer, G | 1 |
| Bachmann, T; Jurna, I; Theres, C | 1 |
| Glasky, AJ; Simon, LN | 1 |
| Saito, A; Shibata, M; Takagi, K; Watanabe, M | 1 |
| Fog, R | 1 |
| Scheel-Krüger, J | 1 |
| Kulkarni, AS | 1 |
| Honma, T; Inaba, S; Kitagawa, S; Ono, K; Sasajima, K; Yamamoto, H | 1 |
| Grahame-Smith, DG; Green, AR; Hammond, M; O'Shaughnessy, K; Schächter, M | 1 |
| Sonsalla, PK; Terleckyj, I | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Ogita, K; Yamada, K; Yoneda, Y | 1 |
| Ferkany, J; Hickey, P; Katz, JL; Menkel, M; Pontecorvo, M; Terry, P; Witkin, JM | 1 |
| Larson, J; LeDuc, BQ; Lynch, G; Nguyen, A; Quach, CN; Rogers, GA | 1 |
| Ito, C; Onodera, K; Sato, M; Watanabe, T | 1 |
| Itoh, C; Onodera, K; Sato, M; Watanabe, T | 1 |
| Misawa, M; Mori, T; Onodera, K; Suzuki, T; Tsuji, M | 1 |
| Goldberg, SR; Munzar, P; Nosál, R | 1 |
| Arai, A; Herbst, TA; Johnson, SA; Knapp, R; Lutz, D; Luu, NT; Lynch, G; Rogers, GA | 1 |
| Chaki, S; Funakoshi, T; Ikeda, Y; Kawashima, N; Kumagai, T; Nagamine, M; Nakazato, A; Ogawa, SI; Okuyama, S; Suzuki, Y; Tomisawa, K; Yoshikawa, R | 1 |
| Gudelsky, GA; Vorhees, CV; Wallace, TL | 1 |
| Chaki, S; Funakoshi, T; Kameo, K; Kawashima, N; Okuyama, S; Omura, T | 1 |
| Nováková, J; Sulcová, A; Vinklerová, J | 1 |
| Chaki, S; Funakoshi, T; Goto, M; Kameo, K; Kawashima, N; Kumagai, T; Nakazato, A; Okuyama, S; Suzuki, Y; Yoshikawa, R | 1 |
| Barbier, AJ; Chen, J; Dugovic, C; Fung-Leung, WP; Koehl, M; Laposky, AD; Lee, DH; Liu, C; Lovenberg, TW; Ngo, K; Sakurai, E; Toyota, H; Turek, FW; Watanabe, T; Weber, C; Wu, Y; Yanai, K | 1 |
| Mori, T; Narita, M; Onodera, K; Suzuki, T | 1 |
| Angulo, JA; Cadet, JL; Yu, J | 1 |
| BENNETT, PB | 1 |
| ARIENS, EJ; HURKMANS, JA; van der SCHOOT, J; van ROSSUM, J | 1 |
| BOHNER, B; CHEN, G; ENSOR, CR | 1 |
| Gall, CM; Hess, US; Lynch, G; Sandoval, LM; Whalen, SP | 1 |
| Chaki, S; Hirota, S; Kawashima, N; Okuyama, S | 1 |
| Goldberg, SR; Justinova, Z; Munzar, P; Tanda, G | 1 |
| Anggadiredja, K; Hiranita, T; Nakamichi, M; Shoyama, Y; Tanaka, H; Watanabe, S; Yamamoto, T | 1 |
| Goldberg, SR; Solinas, M | 1 |
| Miyatake, M; Nakamura, A; Narita, M; Shibasaki, M; Suzuki, T | 1 |
| Acevedo, SF; de Esch, IJ; Raber, J | 1 |
| Anggadiredja, K; Hiranita, T; Nawata, Y; Sakimura, K; Yamamoto, T | 1 |
| Kuehn, BM | 1 |
| Cho, JH; Jang, CG; Jeong, SM; Kim, HC; Lee, BH; Lee, KW; Lee, SY; Nah, SY; Yoo, JH; Yu, HS | 1 |
| Landa, L; Slais, K; Sulcova, A | 1 |
| Boctor, SY; France, CP; Koek, W; Martinez, JL | 1 |
| Gross, G; Groth, I; Jongen-Relo, A; Rex, A; Wicke, KM | 1 |
| Coop, A; Matsumoto, RR; Shaikh, J; Vedam, S; Wilson, LL | 1 |
| Acevedo, SF; Pfankuch, T; Raber, J; van Meer, P | 1 |
| Li, FQ; Li, YQ; Liu, Y; Lu, L; Wang, X; Wang, XY; Xue, YX; Yu, LL; Zhao, M | 1 |
| Bauzo, RM; Fantegrossi, WE; Goodman, MM; Howell, LL; Manvich, DM; Morales, JC; Votaw, JR | 1 |
| Gilman, JP; Goldberg, SR; Justinova, Z; Makriyannis, A; Panlilio, LV; Schindler, CW; Vemuri, VK | 1 |
| Ando, Y; Mouri, A; Nabeshima, T; Noda, Y; Ozaki, N; Waki, Y; Wang, D; Yamada, K; Yamada, SN; Yoshimi, A | 1 |
| Arrang, JM; Burban, A; Dumoulin, D; Frances, H; Le Pen, G; Rose, C; Sadakhom, C | 1 |
| Barrett, DA; Colado, MI; Feng, S; Gutierrez-Lopez, MD; Llopis, N; O'Shea, E | 1 |
| Jiang, W; Liu, JF; Lu, L; Wang, XY; Xue, YX; Yu, LL; Zhou, SJ | 1 |
| Coop, A; Huber, JD; Kaushal, N; Matsumoto, RR; Seminerio, MJ; Shaikh, J | 1 |
| Boctor, SY; Flores, LC; Martinez, JL; Phelix, CF; Rodriguez, JS | 1 |
| Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Kraus, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ; Zhang, L | 1 |
| Hall, FS; Kitanaka, J; Kitanaka, N; Morita, Y; Nishiyama, N; Takemura, M; Tanaka, K; Tatsuta, T; Uhl, GR | 1 |
| Coop, A; Elliott, M; Iyer, AK; Kaushal, N; Matsumoto, RR; Robson, MJ; Rojanasakul, Y | 1 |
| Beckert, MV; Cheer, JF; Loewinger, GC; Tejeda, HA | 1 |
| Allen, CN; Eastwood, E; Raber, J | 1 |
| Cheer, JF; Glick, SD; Morra, JT | 1 |
| Nawata, Y; Yamaguchi, T; Yamamoto, T | 1 |
| Liu, JF; Lu, L; Shi, J; Sun, LL; Wang, J; Xue, YX; Zhang, Y; Zhao, LY; Zhu, WL | 1 |
| Coop, A; Matsumoto, RR; McCurdy, CR; Robson, MJ; Seminerio, MJ | 1 |
| Jenner, P; Kadowaki Horita, T; Kanda, T; Kobayashi, M; Mori, A | 1 |
| Abe, H; Ebihara, K; Funahashi, H; Ikeda, T; Ishida, Y; Koganemaru, G; Kuramashi, A; Matsuo, H; Nishimori, T; Takeda, R | 1 |
| Chavant, F; Duranti, A; Francheteau, M; Gennequin, B; Maccarrone, M; Makriyannis, A; Nader, J; Rapino, C; Solinas, M; Thiriet, N | 1 |
| Enomoto, T; Kitamura, A; Kiyoshi, A; Konishi, Y; Matsuda, H; Nakako, T; Ochi, Y; Sakai, M; Sumiyoshi, T; Suwa, A; Takai, K; Uematsu, Y; Uruno, Y | 1 |
| Jing, L; Li, JX; Qiu, Y; Zhang, Y | 1 |
| Hamao, K; Hamasaki, R; Kawaura, K; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Leong, KC; Peters, J; Reichel, CM; Schwendt, M; Scofield, MD; See, RE; Trantham-Davidson, H | 1 |
| Kitaichi, K; Nawata, Y; Yamamoto, T | 1 |
| Banks, ML | 1 |
| Chen, G; Li, L; Li, T; Liu, X; Qiao, C | 1 |
| Chen, G; Hou, Y; Li, L; Li, T; Liu, X; Qian, H; Qiao, C | 1 |
| Dang, DK; Jang, CG; Jeong, JH; Kim, HC; Ledent, C; Mai, AT; Nabeshima, T; Nah, SY; Onaivi, ES; Shin, EJ; Yamamoto, T | 1 |
| Bing, G; Byun, JK; Dang, DK; Hong, JS; Jang, CG; Jeong, JH; Kim, DJ; Kim, HC; Ko, SK; Nah, SY; Shin, EJ; Tran, HQ | 1 |
| Berro, LF; Howell, LL; Odabas-Geldiay, M; Rice, KC; Shields, H | 1 |
| Fukumori, R; Nawata, Y; Yamaguchi, T; Yamamoto, T | 1 |
| Funada, D; Ikeda, K; Kotajima-Murakami, H; Maruo, K; Matsumoto, T; Murakami, M; Ogai, Y; Sasaki, T; Tachimori, H; Takano, A; Tanibuchi, Y; Tsukamoto, S | 1 |
| Chen, G; Chen, T; Li, T; Liu, X; Qian, H; Qiao, C; Shang, Q; Wang, J; Xiao, J; Zhang, P | 1 |
| Ikeda, K; Kotajima-Murakami, H | 1 |
| Madden, JT; Pentkowski, NS; Reyna, NC | 1 |
| Gulley, JM; Westbrook, SR | 1 |
| Galaj, E; Xi, ZX | 1 |
| Campbell, HL; Hawley, LL; Horchar, MJ; Kappesser, JL; Wright, MR; Yates, JR | 1 |
| Ban, E; Funada, D; Hirakawa, S; Ikeda, K; Kawashima, T; Kikuchi, M; Kotajima-Murakami, H; Maruo, K; Matsumoto, T; Ogai, Y; Oi, H; Sasaki, T; Tachimori, H; Takano, A; Tanibuchi, Y; Tomo, Y | 1 |
3 review(s) available for methamphetamine and piperidines
| Article | Year |
|---|---|
Neuropharmacological profile of an atypical antipsychotic, NRA0562.
Topics: Animals; Antipsychotic Agents; Brain; Dopamine Antagonists; Humans; Methamphetamine; Motor Activity; Neuropharmacology; Piperidines; Receptors, Dopamine; Schizophrenia; Serotonin Antagonists; Thiazoles | 2003 |
[Clinical study of GIRK channel inhibitors as candidate medicines for drug dependence].
Topics: Amphetamine-Related Disorders; Animals; Clinical Trials as Topic; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Japan; Methamphetamine; Neurons; Piperidines; Reward; Substance-Related Disorders | 2020 |
Possible Receptor Mechanisms Underlying Cannabidiol Effects on Addictive-like Behaviors in Experimental Animals.
Topics: Animals; Behavior, Animal; Brain; Cannabidiol; Cannabinoids; Disease Models, Animal; Dopamine; Humans; Methamphetamine; Piperidines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptor, Serotonin, 5-HT1A; Recurrence; Reward; Self Administration; Substance-Related Disorders; TRPV Cation Channels | 2020 |
2 trial(s) available for methamphetamine and piperidines
| Article | Year |
|---|---|
Study of effects of ifenprodil in patients with methamphetamine dependence: Protocol for an exploratory, randomized, double-blind, placebo-controlled trial.
Topics: Adult; Amphetamine-Related Disorders; Double-Blind Method; Female; Humans; Male; Methamphetamine; Off-Label Use; Piperidines; Potassium Channel Blockers; Treatment Outcome | 2019 |
Ifenprodil for the treatment of methamphetamine use disorder: An exploratory, randomized, double-blind, placebo-controlled trial.
Topics: Central Nervous System Stimulants; Double-Blind Method; Humans; Methamphetamine; Piperidines | 2022 |
95 other study(ies) available for methamphetamine and piperidines
| Article | Year |
|---|---|
[Pharmacological studies of an antipschotic agent, penfluridol. (1). The central pharmacological actions].
Topics: Agonistic Behavior; Animals; Apomorphine; Avoidance Learning; Blepharoptosis; Body Temperature; Catalepsy; Cats; Central Nervous System; Chlorpromazine; Conditioning, Classical; Cooperative Behavior; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Haloperidol; Haplorhini; Hexobarbital; Humans; Locomotion; Male; Methamphetamine; Mice; Parasympatholytics; Penfluridol; Piperidines; Rats | 1976 |
[Biological fate of 3H-labeled penfluridol. (3) Correlation between concentration of 3H-penfluridol in the brain and its anti-methamphetamine activity].
Topics: Animals; Brain Chemistry; Mastication; Methamphetamine; Penfluridol; Piperidines; Rats; Tritium | 1976 |
Persistent supersensitivity of sigma receptors develops during repeated methamphetamine treatment.
Topics: Animals; Behavior, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Drug Tolerance; Male; Methamphetamine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma | 1992 |
Polyamines modulate events mediated by the N-methyl-D-aspartate (NMDA) receptor complex through an ifenprodil-insensitive pathway: in vivo measurements of cyclic GMP in the cerebellum.
Topics: Animals; Biogenic Polyamines; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Injections, Intraventricular; Male; Methamphetamine; Mice; Neural Pathways; Ornithine; Pentylenetetrazole; Piperidines; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice.
Topics: Amino Acids; Animals; Corpus Striatum; Dizocilpine Maleate; Male; Methamphetamine; Mice; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1991 |
Effects of sigma ligands on mouse cerebellar cyclic guanosine monophosphate (cGMP) levels in vivo: further evidence for a functional modulation of N-methyl-D-aspartate (NMDA) receptor complex-mediated events by sigma ligands.
Topics: Animals; Cerebellum; Cyclic GMP; Dopamine Agents; Harmaline; Ligands; Male; Methamphetamine; Mice; Pentylenetetrazole; Piperidines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma; Serine | 1991 |
Inhibition of climbing and mossy fiber, and basket and stellate cell inputs to mouse cerebellar Purkinje cells by novel anti-ischemic agents, ifenprodil and BMY-14802.
Topics: Analysis of Variance; Animals; Cyclic GMP; Harmaline; Male; Methamphetamine; Mice; Mice, Inbred Strains; Neurons; Pentylenetetrazole; Piperazines; Piperidines; Purkinje Cells; Pyrimidines; Radioimmunoassay; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Determination of methamphetamine, amphetamine and piperidine in human urine by high-performance liquid chromatography with chemiluminescence detection.
Topics: Amphetamine; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Luminescent Measurements; Methamphetamine; Piperidines | 1990 |
Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Haloperidol; Male; Methamphetamine; Methiothepin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1988 |
Anti-serotonin action in combination with noradrenaline-stimulating action is important for inhibiting muricide in midbrain raphe-lesioned rats.
Topics: Aggression; Animals; Catecholamines; Cinanserin; Dose-Response Relationship, Drug; Drug Interactions; Male; Methamphetamine; Norepinephrine; Piperidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin Antagonists | 1988 |
Central nervous actions and screening methods of antidepressants.
Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Amines; Blood Pressure; Brain Chemistry; Central Nervous System; Diazepam; Electroshock; Ethanol; Hexobarbital; Hypertension; Hypothermia, Induced; Imipramine; Iproniazid; Methamphetamine; Mice; Nialamide; Physostigmine; Piperidines; Reserpine; Tremorine | 1972 |
Effects of metamphetamine, pipradrol and methylphenidate on instrumental conditioning and spontaneous motor activity in the immature rat.
Topics: Animals; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Female; Male; Methamphetamine; Methylphenidate; Motor Activity; Piperidines; Rats; Reinforcement Schedule; Time Factors | 1974 |
Reserpine rigidity in the rat--a model for the analysis of antiparkinson drugs.
Topics: 1-Propanol; Animals; Biperiden; Cerebral Decortication; Electromyography; Methamphetamine; Models, Neurological; Motor Neurons; Movement Disorders; Parasympatholytics; Parkinson Disease; Piperidines; Rats; Reserpine | 1968 |
Depression by antiparkinson drugs of reserpine rigidity.
Topics: 1-Propanol; Animals; Biperiden; Cyclohexanes; Depression, Chemical; Electromyography; Methamphetamine; Movement Disorders; Parasympatholytics; Phenytoin; Piperidines; Rats; Reserpine; Sympathomimetics | 1968 |
The antagonism between reserpine and some antiparkinson drugs in electroseizure.
Topics: 1-Propanol; Animals; Atropine; Biperiden; Cyclohexanes; Dextroamphetamine; Dihydroxyphenylalanine; Electroshock; Methamphetamine; Parasympatholytics; Piperidines; Rats; Reserpine; Sympathomimetics; Tachyphylaxis; Tetrabenazine; Thiocarbamates; Tyrosine | 1968 |
Inhibition of the effect of reserpine on motor control by drugs which influence reserpine rigidity.
Topics: 1-Propanol; Animals; Atropine; Biperiden; Cyclohexanes; Cyclopentanes; Depression, Chemical; Dihydroxyphenylalanine; Methamphetamine; Motor Activity; Motor Neurons; Movement Disorders; Parasympathomimetics; Phenytoin; Piperidines; Rats; Reserpine; Spinal Cord; Sympathomimetics; Trihexyphenidyl | 1969 |
The effect of physostigmine and tetrabenazine on spinal motor control and its inhibition by drugs which influence reserpine rigidity.
Topics: 1-Propanol; Animals; Atropine; Biperiden; Dihydroxyphenylalanine; Electric Stimulation; Electromyography; Methamphetamine; Motor Neurons; Movement Disorders; Parasympatholytics; Phenytoin; Physostigmine; Piperidines; Rats; Reserpine; Spinal Cord; Spinal Nerves; Tetrabenazine; Trihexyphenidyl | 1969 |
Magnesium pemoline: enhancement of brain RNA polymerases.
Topics: Animals; Anticonvulsants; Brain; Imipramine; In Vitro Techniques; Magnesium; Methamphetamine; Methylphenidate; Nucleotidyltransferases; Oxazoles; Pargyline; Pemoline; Piperidines; Rats; RNA; Trimethadione | 1966 |
[Studies of drug action on the behavior of small animals. I. Central nervous system stimulants and their combined effects].
Topics: Animals; Behavior, Animal; Caffeine; Lysergic Acid Diethylamide; Methamphetamine; Methylphenidate; Piperidines; Rats; Stimulation, Chemical | 1967 |
Stereotyped and non-stereotyped behaviour in rats induced by various stimulant drugs.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Caffeine; Central Nervous System; Cocaine; Lysergic Acid Diethylamide; Male; Methamphetamine; Methylphenidate; Nikethamide; Pemoline; Phenmetrazine; Piperidines; Rats | 1969 |
Comparative studies of various amphetamine analogues demonstrating different interactions with the metabolism of the catecholamines in the brain.
Topics: Animals; Behavior, Animal; Brain Chemistry; Carboxylic Acids; Catecholamines; Dextroamphetamine; Dopamine; Male; Methamphetamine; Methylphenidate; Methyltyrosines; Norepinephrine; Phenmetrazine; Piperidines; Rats; Reserpine; Time Factors | 1971 |
Avoidance acquisition and CNS stimulants.
Topics: Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Discrimination Learning; Ephedrine; Male; Methamphetamine; Methylphenidate; Pemoline; Piperidines; Rats; Rats, Inbred Strains | 1972 |
Synthesis and preliminary pharmacology of a novel butyrophenone derivative, ID-4708.
Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Butyrophenones; Catalepsy; Cats; Chlorpromazine; Drug Evaluation, Preclinical; Drug Synergism; Electroencephalography; Epinephrine; Haloperidol; Hexobarbital; Humans; Hydrocarbons, Fluorinated; Imipramine; Lethal Dose 50; Male; Methamphetamine; Mice; Motor Activity; Pain; Piperidines; Rats; Trifluperidol | 1974 |
Inhibition of 5-hydroxytryptamine-mediated behaviour by the putative 5-HT2 antagonist pirenperone.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Haloperidol; Male; Methamphetamine; Motor Activity; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tranylcypromine; Tryptophan | 1983 |
The sigma receptor ligand (+/-)-BMY 14802 prevents methamphetamine-induced dopaminergic neurotoxicity via interactions at dopamine receptors.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Brain Diseases; Butaclamol; Carbazoles; Dizocilpine Maleate; Dopamine; Dopamine Agents; Drug Interactions; Drug Synergism; Guanidines; Ligands; Male; Methamphetamine; Mice; MPTP Poisoning; Neostriatum; Piperidines; Psychotropic Drugs; Pyrimidines; Receptors, Dopamine; Receptors, sigma; Stereoisomerism; Tyrosine 3-Monooxygenase | 1994 |
Risperidone prevents the development of supersensitivity, but not tolerance, to phencyclidine in rats treated with subacute phencyclidine.
Topics: Animals; Antipsychotic Agents; Dizocilpine Maleate; Drug Tolerance; Haloperidol; Isoxazoles; Male; Methamphetamine; Motor Activity; Phencyclidine; Piperidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, Serotonin; Risperidone; Ritanserin | 1995 |
Effects of the selective sigma receptor ligand, 6-[6-(4-hydroxypiperidinyl)hexyloxy]-3-methylflavone (NPC 16377), on behavioral and toxic effects of cocaine.
Topics: Animals; Cocaine; Conditioning, Psychological; Discrimination Learning; Flavonoids; Male; Methamphetamine; Mice; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Seizures | 1993 |
Effects of an AMPA receptor modulator on methamphetamine-induced hyperactivity in rats.
Topics: Animals; Dopamine Agents; Half-Life; Hippocampus; Hyperkinesis; In Vitro Techniques; Male; Methamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stereotyped Behavior; Synaptic Transmission | 1996 |
Effects of histamine agents on methamphetamine-induced stereotyped behavior and behavioral sensitization in rats.
Topics: Animals; Benzothiazoles; Brain; Central Nervous System Stimulants; Histamine Agents; Histidine; Male; Methamphetamine; Methylhistidines; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Stereotyped Behavior; Thiazoles | 1997 |
Motor behavioural function for histamine-dopamine interaction in brain.
Topics: Animals; Benzazepines; Benzothiazoles; Brain; Brain Chemistry; Central Nervous System Stimulants; Dopamine Agents; Dopamine Antagonists; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Methamphetamine; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Stereotyped Behavior; Thiazoles | 1998 |
Generalization of D-, L- and DL-chlorpheniramine and zolantidine to the discriminative stimulus effects of cocaine and methamphetamine.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzothiazoles; Chlorpheniramine; Clomipramine; Cocaine; Desipramine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Stimulus; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Methamphetamine; Middle Aged; Phenoxypropanolamines; Piperazines; Piperidines; Rats; Rats, Inbred F344; Thiazoles | 1997 |
Potentiation of the discriminative-stimulus effects of methamphetamine by the histamine H3 receptor antagonist thioperamide in rats.
Topics: Animals; Central Nervous System Stimulants; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Histamine; Histamine Agonists; Histamine Antagonists; Male; Methamphetamine; Methylhistamines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Time Factors | 1998 |
Synergistic interactions between ampakines and antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Catalepsy; Central Nervous System Stimulants; Dioxoles; Drug Synergism; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Haloperidol; Male; Methamphetamine; Motor Activity; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1999 |
A selective dopamine D4 receptor antagonist, NRA0160: a preclinical neuropharmacological profile.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Brain; Catalepsy; Clozapine; Dopamine D2 Receptor Antagonists; Drug Evaluation, Preclinical; Locomotion; Male; Maze Learning; Methamphetamine; Mice; Mice, Inbred ICR; Piperidines; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D4; Reflex, Startle; Stereotyped Behavior; Swimming; Thiazoles | 1999 |
Effects of lubeluzole on the methamphetamine-induced increase in extracellular glutamate and the long-term depletion of striatal dopamine.
Topics: Animals; Body Temperature; Dopamine; Drug Interactions; Extracellular Space; Glutamic Acid; Male; Methamphetamine; Neostriatum; Neurons; Neuroprotective Agents; Piperidines; Rats; Rats, Sprague-Dawley; Sodium Channels; Thiazoles; Veratridine | 2001 |
Neuropharmacological profiles of a novel atypical antipsychotic, NRA0562, in rats.
Topics: Action Potentials; Animals; Antipsychotic Agents; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Methamphetamine; Neurons; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Risperidone; Thiazoles | 2001 |
Inhibition of methamphetamine self-administration in rats by cannabinoid receptor antagonist AM 251.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Ligands; Male; Methamphetamine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Reinforcement Schedule; Self Administration; Substance Abuse, Intravenous | 2002 |
In vitro and in vivo pharmacological profile of 5-[2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl]-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562), a novel and putative atypical antipsychotic.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Catalepsy; Central Nervous System Stimulants; Clozapine; Humans; Male; Methamphetamine; Motor Activity; Piperidines; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Drug; Receptors, Serotonin; Risperidone; Stereotyped Behavior; Thiazoles | 2002 |
Behavioral characterization of mice lacking histamine H(3) receptors.
Topics: Adjuvants, Anesthesia; Amnesia; Animals; Avoidance Learning; Brain; Dopamine; Dopamine Agents; Histamine Antagonists; Methamphetamine; Mice; Mice, Knockout; Motor Activity; Norepinephrine; Piperidines; Radioligand Assay; Receptors, Histamine H3; Running; Scopolamine; Serotonin | 2002 |
Modulation of the discriminative stimulus effects of cocaine and methamphetamine by the histaminergic system.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Discrimination Learning; Drug Synergism; Histamine; Histamine Antagonists; Histidine; Male; Methamphetamine; Piperidines; Rats; Rats, Inbred F344; Receptors, Histamine H1; Receptors, Histamine H3 | 2002 |
Neurokinin-1 (NK-1) receptor antagonists abrogate methamphetamine-induced striatal dopaminergic neurotoxicity in the murine brain.
Topics: Androstanes; Animals; Autoradiography; Benzimidazoles; Binding Sites; Brain; Brain Chemistry; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fever; Glial Fibrillary Acidic Protein; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Neuroprotective Agents; Piperidines; Signal Transduction; Substance P; Tyrosine 3-Monooxygenase | 2002 |
Comparison of the effects of drugs on nitrogen narcosis and oxygen toxicity in rats.
Topics: Animals; Bemegride; Carbachol; Epinephrine; Glutethimide; Hyperoxia; Inert Gas Narcosis; Methamphetamine; Nitrogen; Oxygen; Pentylenetetrazole; Phenacetin; Physostigmine; Piperidines; Rats; Scopolamine | 1962 |
Phenylisopropylamine derivatives, structure and action.
Topics: Amphetamine; Chlorpromazine; Dibucaine; Diethylpropion; Dihydroxyphenylalanine; Dopamine; Ephedrine; Epinephrine; Hydrazines; Imipramine; Iproniazid; Mephentermine; Methamphetamine; Methylphenidate; Movement; Nialamide; Phenelzine; Phenethylamines; Phenmetrazine; Phenylhydrazines; Piperidines; Reserpine; Tranylcypromine; Tryptophan; Tyramine | 1962 |
INVESTIGATION ON THE SYMPATHOMIMETIC PROPERTIES OF PHENCYCLIDINE BY COMPARISON WITH COCAINE AND DESOXYEPHEDRINE.
Topics: Anesthetics; Animals; Anticonvulsants; Blood Pressure; Central Nervous System; Cocaine; Dogs; Fluids and Secretions; Guanidine; Guanidines; Iproniazid; Methamphetamine; Nervous System; Pharmacology; Phencyclidine; Piperidines; Research; Reserpine; Sympathomimetics; Urine | 1965 |
Ampakines reduce methamphetamine-driven rotation and activate neocortex in a regionally selective fashion.
Topics: Adrenergic Agents; Animals; Autoradiography; Behavior, Animal; Cell Count; Central Nervous System Stimulants; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Immunohistochemistry; In Situ Hybridization; Male; Methamphetamine; Neocortex; Oxazines; Oxidopamine; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Rotation; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2003 |
Histamine h3 receptor antagonists potentiate methamphetamine self-administration and methamphetamine-induced accumbal dopamine release.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Histamine Antagonists; Imidazoles; Male; Methamphetamine; Microdialysis; Nucleus Accumbens; Piperidines; Rats; Rats, Sprague-Dawley; Self Administration; Thiourea; Time Factors | 2004 |
Endocannabinoid system modulates relapse to methamphetamine seeking: possible mediation by the arachidonic acid cascade.
Topics: Amphetamine-Related Disorders; Animals; Arachidonic Acid; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Central Nervous System Stimulants; Cues; Cyclooxygenase Inhibitors; Diclofenac; Dronabinol; Endocannabinoids; Extinction, Psychological; Male; Methamphetamine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Secondary Prevention; Self Administration | 2004 |
Motivational effects of cannabinoids and opioids on food reinforcement depend on simultaneous activation of cannabinoid and opioid systems.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Dronabinol; Drug Combinations; Drug Interactions; Eating; Food; Food Deprivation; Male; Methamphetamine; Morphine; Motivation; Narcotics; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Opioid; Reinforcement Schedule; Reinforcement, Psychology; Rimonabant; Time Factors | 2005 |
Glutamatergic neurotransmission and protein kinase C play a role in neuron-glia communication during the development of methamphetamine-induced psychological dependence.
Topics: Amphetamine-Related Disorders; Animals; Astrocytes; Calcium; Cell Communication; Central Nervous System Stimulants; Coculture Techniques; Conditioning, Operant; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Immunohistochemistry; Male; Methamphetamine; Mice; Mice, Inbred ICR; Microscopy, Confocal; Neuroglia; Neurons; Piperidines; Pregnancy; Protein Kinase C; Pyridines; Quinoxalines; Receptors, Glutamate; Synaptic Transmission | 2005 |
Sex- and histamine-dependent long-term cognitive effects of methamphetamine exposure.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Cognition; Dopamine Uptake Inhibitors; Exploratory Behavior; Histamine; Histamine Antagonists; Imidazoles; Inhibition, Psychological; Maze Learning; Methamphetamine; Mice; Mice, Inbred C57BL; Piperidines; Reflex, Startle; Rotarod Performance Test; Sex Characteristics; Spatial Behavior | 2007 |
Suppression of methamphetamine-seeking behavior by nicotinic agonists.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain; Cholinesterase Inhibitors; Donepezil; Indans; Lidocaine; Male; Mecamylamine; Methamphetamine; Nicotine; Nicotinic Agonists; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine | 2006 |
Nicotine, donepezil may dampen meth craving.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Agents; Donepezil; Humans; Indans; Methamphetamine; Nicotine; Piperidines | 2006 |
Involvement of 5-HT receptors in the development and expression of methamphetamine-induced behavioral sensitization: 5-HT receptor channel and binding study.
Topics: Algorithms; Animals; Autoradiography; Behavior, Animal; Dopamine Uptake Inhibitors; Imidazoles; Indoles; Male; Methamphetamine; Mice; Mice, Inbred ICR; Microinjections; Motor Activity; Oocytes; Piperidines; Receptors, Serotonin, 5-HT3; RNA, Complementary; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes; Xenopus laevis | 2006 |
Impact of cannabinoid receptor ligands on behavioural sensitization to antiaggressive methamphetamine effects in the model of mouse agonistic behaviour.
Topics: Agonistic Behavior; Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Drug Administration Schedule; Drug Interactions; Indoles; Ligands; Male; Methamphetamine; Mice; Mice, Inbred ICR; Piperidines; Pyrazoles; Random Allocation; Receptors, Cannabinoid; Statistics, Nonparametric | 2006 |
The cannabinoid CB1 receptor antagonist AM251 does not modify methamphetamine reinstatement of responding.
Topics: Animals; Body Temperature; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Dronabinol; Infusions, Intravenous; Injections, Intraperitoneal; Male; Methamphetamine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reinforcement Schedule; Self Administration; Time Factors | 2007 |
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine | 2007 |
Attenuation of methamphetamine-induced effects through the antagonism of sigma (sigma) receptors: Evidence from in vivo and in vitro studies.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Cell Line, Tumor; Cell Shape; Cytokines; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Methamphetamine; Mice; Motor Activity; Neuroblastoma; Oxalates; Piperidines; Protein Binding; Radioligand Assay; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, sigma; Time Factors | 2008 |
Role of histamine in short- and long-term effects of methamphetamine on the developing mouse brain.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Central Nervous System Stimulants; Corticosterone; Enzyme-Linked Immunosorbent Assay; Female; Histamine; Histamine H3 Antagonists; Hypothalamo-Hypophyseal System; Imidazoles; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Piperidines; Pituitary-Adrenal System; Sex Factors; Time Factors | 2008 |
Effects of cannabinoid CB1 receptor antagonist rimonabant in consolidation and reconsolidation of methamphetamine reward memory in mice.
Topics: Animals; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Male; Memory; Methamphetamine; Mice; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reward; Rimonabant | 2009 |
Role of dopamine transporters in the behavioral effects of 3,4-methylenedioxymethamphetamine (MDMA) in nonhuman primates.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Electrochemical Techniques; Female; Fluorine Radioisotopes; Fluorobenzenes; Hallucinogens; Macaca mulatta; Magnetic Resonance Spectroscopy; Male; Methamphetamine; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nortropanes; Piperidines; Positron-Emission Tomography; Reinforcement Schedule; Saimiri; Serotonin Antagonists; Tropanes | 2009 |
Effects of cannabinoid receptor antagonists on maintenance and reinstatement of methamphetamine self-administration in rhesus monkeys.
Topics: Animals; Cannabinoid Receptor Antagonists; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Macaca mulatta; Male; Methamphetamine; Piperidines; Pyrazoles; Reinforcement, Psychology; Rimonabant; Secondary Prevention; Self Administration | 2010 |
Galantamine ameliorates the impairment of recognition memory in mice repeatedly treated with methamphetamine: involvement of allosteric potentiation of nicotinic acetylcholine receptors and dopaminergic-ERK1/2 systems.
Topics: Acetylcholine; Adrenergic Uptake Inhibitors; Animals; Cholinesterase Inhibitors; Cognition; Donepezil; Dopamine; Dopamine Agonists; Galantamine; Indans; Male; Memory; Methamphetamine; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Piperidines; Receptors, Muscarinic; Receptors, Nicotinic; Recognition, Psychology | 2010 |
Modulation of prepulse inhibition and stereotypies in rodents: no evidence for antipsychotic-like properties of histamine H3-receptor inverse agonists.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzofurans; Dizocilpine Maleate; Drug Inverse Agonism; Haloperidol; Histamine Antagonists; Imidazoles; Inhibition, Psychological; Male; Methamphetamine; Mice; Phencyclidine; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Stereotyped Behavior | 2010 |
Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine.
Topics: Alcohol Drinking; Amidohydrolases; Animals; Arachidonic Acids; Central Nervous System Stimulants; Choice Behavior; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocannabinoids; Glycerides; Limbic System; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Neurotoxicity Syndromes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1 | 2010 |
Effects of cannabinoid CB₁ receptor antagonist rimonabant on acquisition and reinstatement of psychostimulant reward memory in mice.
Topics: Animals; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Memory; Methamphetamine; Mice; Mice, Inbred Strains; Piperidines; Pyrazoles; Reward; Rimonabant | 2011 |
Sigma (σ) receptor ligand, AC927 (N-phenethylpiperidine oxalate), attenuates methamphetamine-induced hyperthermia and serotonin damage in mice.
Topics: Animals; Body Temperature; Fever; Ligands; Male; Methamphetamine; Mice; Neuroprotective Agents; Oxalates; Piperidines; Receptors, sigma; Serotonin; Serotonin Plasma Membrane Transport Proteins; Visual Cortex | 2011 |
Local pretreatment with the cannabinoid CB1 receptor antagonist AM251 attenuates methamphetamine intra-accumbens self-administration.
Topics: Animals; Central Nervous System Stimulants; Conditioning, Operant; Drug Interactions; Male; Methamphetamine; Microdialysis; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Self Administration | 2011 |
1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 positive allosteric modulators for the treatment of psychosis.
Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Biological Availability; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Dogs; Humans; Hyperkinesis; Imidazoles; In Vitro Techniques; Methamphetamine; Mice; Microsomes, Liver; Models, Molecular; Piperidines; Protein Conformation; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism; Structure-Activity Relationship | 2011 |
Histamine H3 receptor agonists decrease hypothalamic histamine levels and increase stereotypical biting in mice challenged with methamphetamine.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Histamine; Histamine Agonists; Hypothalamus; Imidazoles; Male; Methamphetamine; Methylhistamines; Mice; Motor Activity; Piperidines; Random Allocation; Stereotyped Behavior; Thiourea | 2011 |
AC927, a σ receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells.
Topics: Apoptosis; Cell Line, Tumor; Dopamine; Flow Cytometry; Humans; Methamphetamine; Oxalates; Piperidines; Reactive Nitrogen Species; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, sigma; Tyrosine 3-Monooxygenase | 2012 |
Methamphetamine-induced dopamine terminal deficits in the nucleus accumbens are exacerbated by reward-associated cues and attenuated by CB1 receptor antagonism.
Topics: Animals; Cues; Dopaminergic Neurons; Male; Methamphetamine; Nucleus Accumbens; Piperidines; Presynaptic Terminals; Pyrazoles; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB1; Reward; Rimonabant | 2012 |
Effects of neonatal methamphetamine and thioperamide exposure on spatial memory retention and circadian activity later in life.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Central Nervous System Stimulants; Circadian Rhythm; Conditioning, Psychological; Cues; Exploratory Behavior; Fear; Female; Functional Laterality; Histamine H3 Antagonists; Inhibition, Psychological; Male; Maze Learning; Methamphetamine; Mice; Mice, Inbred C57BL; Piperidines; Retention, Psychology; Sensory Gating; Sex Factors; Spatial Behavior | 2012 |
Cannabinoid receptors mediate methamphetamine induction of high frequency gamma oscillations in the nucleus accumbens.
Topics: Animals; Brain Waves; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Interneurons; Male; Methamphetamine; Nerve Tissue Proteins; Neurotoxicity Syndromes; Nucleus Accumbens; Piperidines; Psychomotor Performance; Psychotic Disorders; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Rimonabant | 2012 |
[JSNP Excellent Presentation Award for AsCNP 2011: improvement of cognitive impairments on withdrawal after repeated methamphetamine by administration of a cannabinoid CB1 receptor antagonist and a COX inhibitor].
Topics: Animals; Awards and Prizes; Cognition Disorders; Cyclooxygenase Inhibitors; Diclofenac; Male; Methamphetamine; Mice; Mice, Inbred ICR; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Substance Withdrawal Syndrome | 2012 |
Role of melanin-concentrating hormone in the nucleus accumbens shell in rats behaviourally sensitized to methamphetamine.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Central Nervous System Stimulants; Disease Models, Animal; Drug Interactions; Hypothalamic Hormones; Male; MAP Kinase Signaling System; Melanins; Methamphetamine; Motor Activity; Nucleus Accumbens; Piperidines; Pituitary Hormones; Rats; Rats, Sprague-Dawley | 2013 |
σ Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation.
Topics: Animals; Benzothiazoles; Body Temperature; Corpus Striatum; Dopamine; Dopamine Agents; Fever; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Oxalates; Piperazines; Piperidines; Receptors, sigma | 2013 |
Effects of the adenosine A2A antagonist istradefylline on cognitive performance in rats with a 6-OHDA lesion in prefrontal cortex.
Topics: Adenosine A2 Receptor Antagonists; Animals; Cognition; Cognition Disorders; Disease Models, Animal; Donepezil; Dopamine; Indans; Male; Memory Disorders; Memory, Short-Term; Methamphetamine; Oxidopamine; Piperidines; Prefrontal Cortex; Purines; Rats; Rats, Sprague-Dawley | 2013 |
Effect of blonanserin on methamphetamine-induced disruption of latent inhibition and c-Fos expression in rats.
Topics: Amygdala; Animals; Antipsychotic Agents; Conditioning, Classical; Dopamine Antagonists; Dopamine Uptake Inhibitors; Male; Methamphetamine; Nucleus Accumbens; Piperazines; Piperidines; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2013 |
Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors.
Topics: Animals; Arachidonic Acids; Benzamides; Benzodioxoles; Cannabinoid Receptor Modulators; Carbamates; Central Nervous System Stimulants; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Glycerides; Male; Methamphetamine; Mice, Inbred C57BL; Neostriatum; Neurotoxicity Syndromes; Piperidines; Polyunsaturated Alkamides; Random Allocation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2014 |
Discovery of N-sulfonyl-7-azaindoline derivatives as potent, orally available and selective M(4) muscarinic acetylcholine receptor agonists.
Topics: Administration, Oral; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Discovery; Humans; Methamphetamine; Molecular Structure; Motor Activity; Piperidines; Rats; Receptor, Muscarinic M4; Structure-Activity Relationship; Sulfonamides | 2014 |
Effects of the cannabinoid CB₁ receptor allosteric modulator ORG 27569 on reinstatement of cocaine- and methamphetamine-seeking behavior in rats.
Topics: Allosteric Regulation; Amphetamine-Related Disorders; Animals; Cocaine-Related Disorders; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Indoles; Male; Methamphetamine; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Recurrence; Rimonabant; Self Administration | 2014 |
Tipepidine increases dopamine level in the nucleus accumbens without methamphetamine-like behavioral sensitization.
Topics: Akathisia, Drug-Induced; Animals; Antidepressive Agents; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Methamphetamine; Microdialysis; Motor Activity; Nucleus Accumbens; Piperidines; Rats, Sprague-Dawley | 2015 |
Failure to Recognize Novelty after Extended Methamphetamine Self-Administration Results from Loss of Long-Term Depression in the Perirhinal Cortex.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Cycloserine; Excitatory Amino Acid Agents; Long-Term Synaptic Depression; Male; Memory Disorders; Methamphetamine; Phenols; Piperidines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Self Administration; Tissue Culture Techniques | 2015 |
Prevention of drug priming- and cue-induced reinstatement of MDMA-seeking behaviors by the CB1 cannabinoid receptor antagonist AM251.
Topics: Amphetamine-Related Disorders; Animals; Cannabinoid Receptor Antagonists; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Pyrazoles; Rats; Self Administration | 2016 |
Effects of 7-day repeated treatment with the 5-HT2A inverse agonist/antagonist pimavanserin on methamphetamine vs. food choice in male rhesus monkeys.
Topics: Animals; Choice Behavior; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Inverse Agonism; Feeding Behavior; Food; Macaca mulatta; Male; Methamphetamine; Piperidines; Reinforcement, Psychology; Self Administration; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Treatment Outcome; Urea | 2016 |
Ifenprodil Attenuates Methamphetamine-Induced Behavioral Sensitization and Activation of Ras-ERK-∆FosB Pathway in the Caudate Putamen.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Extracellular Signal-Regulated MAP Kinases; Genes, ras; Male; MAP Kinase Signaling System; Methamphetamine; Mice, Inbred C57BL; Motor Activity; Piperidines; Proto-Oncogene Proteins c-fos; Putamen; Receptors, N-Methyl-D-Aspartate | 2016 |
Ifenprodil attenuates the acquisition and expression of methamphetamine-induced behavioral sensitization and activation of Ras-ERK1/2 cascade in the caudate putamen.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; MAP Kinase Signaling System; Methamphetamine; Mice, Inbred C57BL; Motor Activity; Nucleus Accumbens; Piperidines; Putamen; Receptors, N-Methyl-D-Aspartate | 2016 |
Genetic or pharmacological depletion of cannabinoid CB1 receptor protects against dopaminergic neurotoxicity induced by methamphetamine in mice.
Topics: Animals; Apoptosis; Butadienes; Cells, Cultured; Corpus Striatum; Dopamine; Extracellular Signal-Regulated MAP Kinases; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxicity Syndromes; Nitriles; Oxidative Stress; Piperidines; Protein Kinase C-delta; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Dopamine D2; Rimonabant; Sulpiride | 2017 |
Ginsenoside Re protects methamphetamine-induced dopaminergic neurotoxicity in mice via upregulation of dynorphin-mediated κ-opioid receptor and downregulation of substance P-mediated neurokinin 1 receptor.
Topics: Animals; Dopamine; Dopaminergic Neurons; Dynorphins; Ginsenosides; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Piperidines; Reactive Oxygen Species; Receptors, Neurokinin-1; Receptors, Opioid, kappa; Substance P; Up-Regulation | 2018 |
Effects of acute treatments with the serotonin 2A antagonist M100907 alone or in combination with the serotonin 2C agonist WAY163909 on methamphetamine self-administration in rhesus monkeys.
Topics: Animals; Azepines; Behavior, Addictive; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorobenzenes; Indoles; Macaca mulatta; Male; Methamphetamine; Piperidines; Reinforcement, Psychology; Self Administration; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Treatment Outcome | 2019 |
Inhibition of Monoacylglycerol Lipase Reduces the Reinstatement of Methamphetamine-Seeking and Anxiety-Like Behaviors in Methamphetamine Self-Administered Rats.
Topics: Amidohydrolases; Amphetamine-Related Disorders; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Addictive; Behavior, Animal; Benzamides; Benzodioxoles; Cannabinoid Receptor Antagonists; Carbamates; Central Nervous System Stimulants; Male; Maze Learning; Methamphetamine; Monoacylglycerol Lipases; Piperidines; Rats; Rats, Wistar | 2019 |
Ifenprodil Attenuates Methamphetamine-Induced Behavioral Sensitization Through the GluN2B-PP2A-AKT Cascade in the Dorsal Striatum of Mice.
Topics: Animals; Behavior, Addictive; Corpus Striatum; Male; Methamphetamine; Mice, Inbred C57BL; Piperidines; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substance-Related Disorders | 2020 |
Antagonizing serotonin 2A (5-HT
Topics: Animals; Anxiety; Behavior, Addictive; Central Nervous System Stimulants; Fluorobenzenes; Male; Methamphetamine; Piperidines; Rats; Reward; Serotonin; Serotonin Antagonists | 2020 |
Effects of the GluN2B antagonist, Ro 25-6981, on extinction consolidation following adolescent- or adult-onset methamphetamine self-administration in male and female rats.
Topics: Age Factors; Amphetamine-Related Disorders; Animals; Conditioning, Operant; Drug-Seeking Behavior; Extinction, Psychological; Female; Male; Memory; Memory Consolidation; Methamphetamine; Phenols; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Self Administration; Sex Factors | 2020 |
Effects of the GluN2B-selective antagonist Ro 63-1908 on acquisition and expression of methamphetamine conditioned place preference in male and female rats.
Topics: Animals; Conditioning, Classical; Female; Male; Methamphetamine; Phenols; Piperidines; Rats | 2021 |