methamphetamine and naltrexone

methamphetamine has been researched along with naltrexone in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's4 (10.53)18.2507
2000's5 (13.16)29.6817
2010's17 (44.74)24.3611
2020's11 (28.95)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hamada, T; Kameyama, T; Nakayama, S; Ukai, M1
Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M2
Kameyama, T; Toyoshi, T; Ukai, M1
Andrews, AM; Cadet, JL; Chiueh, CC; Ladenheim, B; Su, TP; Tsao, LI1
Anggadiredja, K; Hiranita, T; Sakimura, K; Yamamoto, T1
Chiu, CT; Ho, IK; Ma, T1
Kast, RE1
McGregor, IS; van Nieuwenhuijzen, PS1
Grant, JE; Kim, SW; Odlaug, BL1
Baumann, MH; Bossert, JM; Hutchinson, MR; Kambhampati, S; Li, X; Pickens, CL; Rice, KC; Shaham, Y; St Laurent, R; Theberge, FR; Watkins, LR1
Fukushima, Y; Hall, FS; Kitanaka, J; Kitanaka, N; Kubo, H; Morita, Y; Nishiyama, N; Sawai, T; Takahashi, H; Takemura, M; Tanaka, K; Tatsuta, T; Uhl, GR; Watabe, K1
Eastwood, EC; Phillips, TJ1
Glaser, PE; Hays, LR; Pike, E; Rush, CR; Stoops, WW1
Crawford, E; Edwards, S; George, O; Gould, A; Grant, Y; Koob, GF; Schlosburg, JE; Vendruscolo, LF; Wee, S; Whitfield, TW; Zamora-Martinez, ER1
Bujarski, S; Courtney, KE; Heinzerling, K; Leventhal, AM; London, ED; Lunny, K; Miotto, K; Moallem, NR; Ray, LA; Roche, D; Shoptaw, S1
Batki, SL; Coffin, P; DeMartini, A; Euren, J; Hahn, JA; Huffaker, S; Matheson, T; Rowe, C; Santos, D; Santos, GM; Vittinghoff, E; Vlahov, D1
Glaser, PE; Hays, LR; Lile, JA; Marks, KR; Rush, CR; Stoops, WW1
Courtney, KE; Ghahremani, DG; Ray, LA1
Bujarski, S; Courtney, KE; London, ED; Ray, LA; Roche, DJO; Shoptaw, S; Worley, MJ1
Batki, SL; Coffin, PO; Colfax, G; Hern, J; Matheson, T; Santos, D; Santos, GM; Vittinghoff, E1
Dennis, LE; Hoffman, WF; Kohno, M; Korthuis, PT; McCready, H; Schwartz, DL1
Anand, S; Chan, EW; Lam, L; Li, X; Tse, ML; Zhao, JX1
Dong, GM; Guo, LK; Li, J; Lu, GY; Ma, CM; Song, R; Wang, ZY; Wu, N; Zhang, RL1
Courtney, KE; Green, R; Grodin, EN; Lim, AC; London, ED; Meredith, LR; Moallem, NR; Ray, LA; Sayegh, P; Venegas, A1
Dong, GM; Guo, LK; Han, X; Li, J; Ma, CM; Song, R; Wang, ZY; Wu, N1
Bart, G; Carmody, T; Coffin, P; Dela Cruz, A; Ghitza, UE; Kim, M; Ling, W; Nunes, EV; Rush, AJ; Schmitz, J; Sharma, G; Shoptaw, S; Shores-Wilson, K; Sonne, SC; Sparenborg, S; Trivedi, MH; Wahle, A; Wakhlu, S; Walker, R; Wiest, K1
Gainer, DM; Miller, SC; Nahhas, RW; Silverstein, SM; Vanderhoof, SO; Vanderhoof, T; Wright, MD1
Castillo, F; Comer, SD; Jones, JD; Kranzler, HR; Manubay, J; Martinez, S; Mogali, S; Mumtaz, M; Perez, F; Pramanik, S; Vadhan, NP1
Campbell, ANC; Choo, TH; Cook, RR; Lee, JD; Nunes, EV; Pavlicova, M; Rotrosen, J; Shulman, M; Tsui, JI1
Carmody, T; Northrup, TF; Schmitz, JM; Shoptaw, S; Stotts, AL; Trivedi, MH; Villarreal, YR; Weaver, MF; Yammine, L; Yoon, JH1
Carmody, T; Cook, RR; Korthuis, PT; Levander, XA; Potter, JS; Shoptaw, S; Trivedi, MH1
Carmody, TJ; Coffin, PO; Kidd, JD; Levin, FR; Nunes, EV; Shoptaw, SJ; Smiley, SL; Trivedi, MH1
Nawata, Y; Nishioku, T; Ooishi, R; Yamaguchi, T1
Chan, MH; Chen, HH; Chen, LC1

Reviews

3 review(s) available for methamphetamine and naltrexone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Use of FDA approved methamphetamine to allow adjunctive use of methylnaltrexone to mediate core anti-growth factor signaling effects in glioblastoma.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:2

    Topics: Brain Neoplasms; Central Nervous System Stimulants; Drug Approval; Drug Synergism; Glioblastoma; Humans; Methamphetamine; Naltrexone; Narcotic Antagonists; Neovascularization, Pathologic; Quaternary Ammonium Compounds; United States; United States Food and Drug Administration; Vascular Endothelial Growth Factor A

2009
Efficacy and safety of naltrexone for amfetamine and methamfetamine use disorder: a systematic review of randomized controlled trials.
    Clinical toxicology (Philadelphia, Pa.), 2019, Volume: 57, Issue:4

    Topics: Amphetamine; Amphetamine-Related Disorders; Humans; Methamphetamine; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Treatment Outcome

2019

Trials

12 trial(s) available for methamphetamine and naltrexone

ArticleYear
A double-blind, placebo-controlled study of N-acetyl cysteine plus naltrexone for methamphetamine dependence.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:11

    Topics: Acetylcysteine; Adult; Amphetamine-Related Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methamphetamine; Middle Aged; Naltrexone; Young Adult

2010
The Effects of Naltrexone on Subjective Response to Methamphetamine in a Clinical Sample: a Double-Blind, Placebo-Controlled Laboratory Study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:10

    Topics: Adult; Amphetamine-Related Disorders; Analysis of Variance; Blood Pressure; Cross-Over Studies; Cues; Double-Blind Method; Female; Heart Rate; Humans; Male; Methamphetamine; Middle Aged; Naltrexone; Narcotic Antagonists; Sex Characteristics; Surveys and Questionnaires; Time Factors; Young Adult

2015
Feasibility, Acceptability, and Tolerability of Targeted Naltrexone for Nondependent Methamphetamine-Using and Binge-Drinking Men Who Have Sex with Men.
    Journal of acquired immune deficiency syndromes (1999), 2016, May-01, Volume: 72, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Binge Drinking; Condoms; Counseling; Double-Blind Method; Homosexuality, Male; Humans; Male; Methamphetamine; Middle Aged; Naltrexone; Narcotic Antagonists; Placebos; Risk Reduction Behavior; Risk-Taking; Sexual Behavior; Substance-Related Disorders; Unsafe Sex; Young Adult

2016
The Effects of Pharmacological Opioid Blockade on Neural Measures of Drug Cue-Reactivity in Humans.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:12

    Topics: Adult; Behavior, Addictive; Brain; Brain Mapping; Central Nervous System Stimulants; Cues; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Methamphetamine; Naltrexone; Narcotic Antagonists; Oxygen; Substance-Related Disorders

2016
Extended-release naltrexone for methamphetamine dependence among men who have sex with men: a randomized placebo-controlled trial.
    Addiction (Abingdon, England), 2018, Volume: 113, Issue:2

    Topics: Adult; Amphetamine-Related Disorders; Delayed-Action Preparations; Double-Blind Method; Homosexuality, Male; Humans; Male; Methamphetamine; Naltrexone; Narcotic Antagonists; San Francisco; Treatment Outcome

2018
A preliminary randomized clinical trial of naltrexone reduces striatal resting state functional connectivity in people with methamphetamine use disorder.
    Drug and alcohol dependence, 2018, 11-01, Volume: 192

    Topics: Adult; Amphetamine-Related Disorders; Amygdala; Delayed-Action Preparations; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Methamphetamine; Middle Aged; Naltrexone; Narcotic Antagonists; Neural Pathways; Rest; Ventral Striatum

2018
Bupropion and Naltrexone in Methamphetamine Use Disorder.
    The New England journal of medicine, 2021, 01-14, Volume: 384, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amphetamine-Related Disorders; Bupropion; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections; Male; Medication Adherence; Methamphetamine; Middle Aged; Naltrexone; Narcotic Antagonists; Young Adult

2021
The effects of acute oral naltrexone pretreatment on the abuse potential of intranasal methamphetamine, and the relationship between reward/punishment sensitivity and methamphetamine's effects.
    Behavioural pharmacology, 2022, 06-01, Volume: 33, Issue:4

    Topics: Adult; Central Nervous System Stimulants; Double-Blind Method; Female; Humans; Male; Methamphetamine; Naltrexone; Punishment; Reward

2022
Methamphetamine/amphetamine use over time among persons with opioid use disorders treated with buprenorphine/naloxone versus extended-release naltrexone.
    Drug and alcohol dependence, 2022, 07-01, Volume: 236

    Topics: Buprenorphine; Buprenorphine, Naloxone Drug Combination; Delayed-Action Preparations; Humans; Injections, Intramuscular; Methamphetamine; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders

2022
Naltrexone plus bupropion reduces cigarette smoking in individuals with methamphetamine use disorder: A secondary analysis from the CTN ADAPT-2 trial.
    Journal of substance use and addiction treatment, 2023, Volume: 151

    Topics: Bupropion; Cigarette Smoking; Humans; Methamphetamine; Naltrexone; Narcotic Antagonists; Prospective Studies

2023
A gender-based secondary analysis of the ADAPT-2 combination naltrexone and bupropion treatment for methamphetamine use disorder trial.
    Addiction (Abingdon, England), 2023, Volume: 118, Issue:7

    Topics: Adult; Bupropion; Central Nervous System Stimulants; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methamphetamine; Naltrexone; Pregnancy

2023
Sexual orientation differences among men in a randomized clinical trial of extended-release naltrexone and bupropion for methamphetamine use disorder.
    Drug and alcohol dependence, 2023, 09-01, Volume: 250

    Topics: Bupropion; Double-Blind Method; Female; Homosexuality, Male; Humans; Male; Methamphetamine; Naltrexone; Prospective Studies; Sexual and Gender Minorities; Sexual Behavior

2023

Other Studies

23 other study(ies) available for methamphetamine and naltrexone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Discriminative stimulus properties of the mixed agonist-antagonist pentazocine in the rat using two-choice discrete-trial avoidance paradigm.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2

    Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Methamphetamine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Rats; Rats, Inbred Strains

1989
The role of delta-opioid receptor subtypes in cocaine- and methamphetamine-induced place preferences.
    Life sciences, 1994, Volume: 55, Issue:17

    Topics: Animals; Benzylidene Compounds; Cocaine; Conditioning, Psychological; Male; Methamphetamine; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reinforcement, Psychology

1994
DAMGO ([D-Ala2,NMePhe4,Gly-ol]enkephalin), but not DPLPE ([D-Pen2,L- Pen5]enkephalin), specifically inhibits methamphetamine-induced behavioral responses in the mouse.
    Neuropharmacology, 1993, Volume: 32, Issue:10

    Topics: Analgesics; Animals; Behavior, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Methamphetamine; Mice; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists

1993
The role of delta-opioid receptors in the discriminative stimulus properties of a low dose of methamphetamine.
    European journal of pharmacology, 1997, Jul-16, Volume: 331, Issue:1

    Topics: Animals; Benzylidene Compounds; Central Nervous System Stimulants; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Methamphetamine; Naltrexone; Quinolines; Rats; Rats, Inbred F344; Receptors, Opioid, delta

1997
Delta opioid peptide [D-Ala2,D-leu5]enkephalin blocks the long-term loss of dopamine transporters induced by multiple administrations of methamphetamine: involvement of opioid receptors and reactive oxygen species.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Animals; Antioxidants; Body Temperature; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Enkephalin, Leucine-2-Alanine; Glutathione; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Naltrexone; Nerve Tissue Proteins; Reactive Oxygen Species; Receptors, Opioid

1998
Naltrexone attenuates cue- but not drug-induced methamphetamine seeking: a possible mechanism for the dissociation of primary and secondary reward.
    Brain research, 2004, Sep-24, Volume: 1021, Issue:2

    Topics: Animals; Behavior, Addictive; Central Nervous System Stimulants; Conditioning, Operant; Male; Methamphetamine; Naltrexone; Narcotic Antagonists; Rats; Reward; Self Administration

2004
Attenuation of methamphetamine-induced behavioral sensitization in mice by systemic administration of naltrexone.
    Brain research bulletin, 2005, Sep-30, Volume: 67, Issue:1-2

    Topics: Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Methamphetamine; Mice; Naltrexone; Narcotic Antagonists

2005
Sedative and hypothermic effects of gamma-hydroxybutyrate (GHB) in rats alone and in combination with other drugs: assessment using biotelemetry.
    Drug and alcohol dependence, 2009, Aug-01, Volume: 103, Issue:3

    Topics: Animals; Baclofen; Benzazepines; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Flumazenil; Hypothermia; Illicit Drugs; Male; Methamphetamine; Morpholines; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Rats; Rats, Wistar; Ritanserin; Sodium Oxybate; Telemetry

2009
Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving.
    Biological psychiatry, 2013, Apr-15, Volume: 73, Issue:8

    Topics: Animals; Behavior, Addictive; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Drug Administration Schedule; Extinction, Psychological; Heroin; Infusion Pumps, Implantable; Methamphetamine; Naltrexone; Narcotic Antagonists; Rats; Self Administration; Stereoisomerism; Time Factors; Toll-Like Receptor 4

2013
The selective μ opioid receptor antagonist β-funaltrexamine attenuates methamphetamine-induced stereotypical biting in mice.
    Brain research, 2013, Jul-19, Volume: 1522

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Male; Methamphetamine; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Stereotyped Behavior

2013
Morphine intake and the effects of naltrexone and buprenorphine on the acquisition of methamphetamine intake.
    Genes, brain, and behavior, 2014, Volume: 13, Issue:2

    Topics: Amphetamine-Related Disorders; Animals; Buprenorphine; Choice Behavior; Female; Inbreeding; Male; Methamphetamine; Mice; Morphine; Naltrexone; Narcotic Antagonists; Selection, Genetic

2014
Naltrexone and bupropion, alone or combined, do not alter the reinforcing effects of intranasal methamphetamine.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 129

    Topics: Administration, Intranasal; Adult; Bupropion; Humans; Methamphetamine; Naltrexone; Narcotic Antagonists; Surveys and Questionnaires

2015
κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Mar-11, Volume: 35, Issue:10

    Topics: Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Enkephalins; Male; Methamphetamine; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reinforcement, Psychology; Self Administration

2015
Separate and Combined Effects of Naltrexone and Extended-Release Alprazolam on the Reinforcing, Subject-Rated, and Cardiovascular Effects of Methamphetamine.
    Journal of clinical psychopharmacology, 2016, Volume: 36, Issue:3

    Topics: Administration, Intranasal; Adult; Alprazolam; Amphetamine-Related Disorders; Blood Pressure; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; GABA Modulators; Heart Rate; Humans; Male; Methamphetamine; Middle Aged; Naltrexone; Narcotic Antagonists; Psychomotor Performance; Reinforcement, Psychology; Self Administration

2016
Naltrexone moderates the relationship between cue-induced craving and subjective response to methamphetamine in individuals with methamphetamine use disorder.
    Psychopharmacology, 2017, Volume: 234, Issue:13

    Topics: Anxiety; Behavior, Addictive; Conditioning, Psychological; Craving; Cues; Data Collection; Double-Blind Method; Emotions; Humans; Methamphetamine; Naltrexone; Time Factors

2017
Inhibition of naltrexone on relapse in methamphetamine self-administration and conditioned place preference in rats.
    European journal of pharmacology, 2019, Dec-15, Volume: 865

    Topics: Animals; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Male; Methamphetamine; Naltrexone; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Spatial Behavior

2019
Executive function moderates naltrexone effects on methamphetamine-induced craving and subjective responses.
    The American journal of drug and alcohol abuse, 2020, 09-02, Volume: 46, Issue:5

    Topics: Adult; Amphetamine-Related Disorders; Central Nervous System Stimulants; Cognition; Craving; Cross-Over Studies; Double-Blind Method; Executive Function; Female; Humans; Los Angeles; Male; Methamphetamine; Naltrexone; Narcotic Antagonists; Young Adult

2020
Naltrexone attenuates methamphetamine-induced behavioral sensitization and conditioned place preference in mice.
    Behavioural brain research, 2021, 02-05, Volume: 399

    Topics: Amphetamine-Related Disorders; Animals; Behavior, Animal; Central Nervous System Sensitization; Central Nervous System Stimulants; Conditioning, Classical; Disease Models, Animal; Extinction, Psychological; Male; Mental Recall; Methamphetamine; Mice; Motivation; Naltrexone; Narcotic Antagonists

2021
Exploring the Interactions between Non-Medical Methamphetamine Use and Prescribed Buprenorphine or Naltrexone in Opioid Use Disorder Treatment Retention.
    Substance use & misuse, 2021, Volume: 56, Issue:14

    Topics: Buprenorphine; Delayed-Action Preparations; Humans; Injections, Intramuscular; Methamphetamine; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Retrospective Studies

2021
Nalmefene attenuates reinstatement of methamphetamine-seeking behavior in rats through group II metabotropic glutamate receptors (mGluR2/3).
    Behavioural brain research, 2024, 01-05, Volume: 456

    Topics: Animals; Cues; Drug-Seeking Behavior; Extinction, Psychological; Methamphetamine; Naltrexone; Rats; Receptors, Metabotropic Glutamate; Self Administration

2024
Extinction and reinstatement of methamphetamine-induced conditioned place preference in zebrafish.
    Addiction biology, 2023, Volume: 28, Issue:12

    Topics: Animals; Clonidine; Extinction, Psychological; Methamphetamine; Morphine; Naltrexone; Recurrence; Zebrafish

2023