methamphetamine and methylone

methamphetamine has been researched along with methylone in 99 studies

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.01)18.2507
2000's6 (6.06)29.6817
2010's79 (79.80)24.3611
2020's13 (13.13)2.80

Authors

AuthorsStudies
Cozzi, NV; Jacob, P; Ruoho, AE; Shulgin, AT; Sievert, MK1
Bossong, MG; Niesink, RJ; Van Dijk, JP1
Fujisaki, M; Hagiwara, H; Hashimoto, K; Iyo, M; Kojima, T; Miyatake, R; Shimizu, E; Watanabe, H1
Kamata, HT; Kamata, T; Katagi, M; Miki, A; Nishikawa, M; Shima, N; Tsuchihashi, H; Zaitsu, K1
Goda, Y; Kawamura, M; Kikura-Hanajiri, R; Kodama, Y; Saisho, K1
Ishii, H; Nakagawa, Y; Ogata, A; Suzuki, T; Tayama, S1
Goda, Y; Kawahara, N; Kikura-Hanajiri, R; Uchiyama, N1
Maurer, HH; Meyer, MR; Peters, FT; Wilhelm, J1
Coleman, N; McNamara, S; Stokes, S1
Halcomb, S; Hargrave, BY; Lattanzio, FA; Tiangco, DA1
Auger, PL; Boulanger-Gobeil, C; Laliberté, M; St-Onge, M1
Karila, L; Reynaud, M1
Aaron, C; Freeman, S; Hedge, M; Leonard, K; Warrick, BJ; Wilson, J1
Ayestas, MA; Baumann, MH; Brandt, SD; Cozzi, NV; Daley, PF; Partilla, JS; Rothman, RB; Ruoho, AE; Shulgin, AT; Sink, JR1
Kereszty, EM; Kovács, K; Tóth, AR1
Halter, MJ; Levine, C; Wieland, DM1
Camarasa, J; Escubedo, E; López-Arnau, R; Martínez-Clemente, J; Pubill, D2
Cawrse, BM; Dickson, AJ; Fowler, DR; Holler, JM; Jufer, RA; Levine, B; Vorce, SP1
Frazee, CC; Garg, U; Hair, LS; Hargraves, TL; Massucci, CJ; Pearson, JM; Pietak, BR1
Beuhler, MC; Dulaney, AR; Kacinko, S; Murphy, CM1
Chiles, C; Joksovic, P; Mellos, N; van Wattum, PJ1
den Hollander, B; Korpi, ER; Linden, AM; Ojanperä, I; Rozov, S; Uusi-Oukari, M1
Dalgleish, JK; Graham Cooks, R; Mulligan, CC; Ouyang, Z; Shelley, JT; Wleklinski, M1
Carbone, DL; Carbone, PN; Carstairs, SD; Luzi, SA1
Belton, P; Maguire, FM; Polhemus, M; Sharngoe, T1
Linnet, K; Pedersen, AJ; Petersen, TH1
Camarasa, J; Carbó, Ml; Escubedo, E; López-Arnau, R; Martínez-Clemente, J; Pubill, D1
Beck, O; Hägerkvist, R; Helander, A; Hultén, P1
Aldridge, L; Hamm, CE; McIntyre, IM; Nelson, CL1
Banks, ML; Bonano, JS; De Felice, LJ; Glennon, RA; Negus, SS1
Gregg, RA; Rawls, SM1
Channell, KB; Endres, GW; Fantegrossi, WE; James, LP; McCain, KR; Moran, CL; Moran, JH; Patton, AL; Prather, PL; Radominska-Pandya, A; Seely, KA; Smith, NH; Womack, ML1
Abad, S; Camarasa, J; Escubedo, E; López-Arnau, R; Martínez-Clemente, J; Pubill, D1
Andersson, M; Karlsson, L; Kronstrand, R; Kugelberg, FC1
Baumann, MH; Kim, AH; Kiyatkin, EA; Shaham, Y; Wakabayashi, KT1
Couper, FJ; Knoy, JL; Peterson, BL1
ElJordi, OI; Liu, K; Poklis, A; Poklis, JL; Wolf, CE; Zhang, S1
Driver, CR; Hoffman, RS; Jakubowski, A; Karpati, A; Kass, D; Kunins, HV; Nelson, LS; Nolan, ML; Paone, D; Ridpath, A1
Bernal, I; Lalancette, RA; Wood, MR1
Creehan, KM; Taffe, MA; Vandewater, SA2
Angoa-Pérez, M; Anneken, JH; Kuhn, DM1
Goda, Y; Hall, FS; Ito, M; Kikura-Hanajiri, R; Lesch, KP; Moriya, Y; Murphy, DL; Ohara, A; Piao, YS; Sora, I; Uhl, GR1
Aarde, SM; Creehan, KM; Miller, ML; Taffe, MA; Vandewater, SA1
Sande, M1
Barrios, L; Boels, D; Bouquie, R; Clement, R; Grison-Hernando, H; Monteil-Ganiere, C1
Baumann, MH; Brandt, SD; Cozzi, NV; Goldberg, SR; Lehner, KR; Schindler, CW; Thorndike, EB1
Cleland, CM; Palamar, JJ; Salomone, A; Vincenti, M1
Benyamina, A; Billieux, J; Cottencin, O; Karila, L; Lançon, C1
Creehan, KM; Grant, Y; Nguyen, JD; Taffe, MA; Vandewater, SA1
Banks, ML; Blough, BE; Negus, SS; Poklis, JL; Smith, DA1
Addison, JW; Bosy, TZ; Briones, AJ; King, TD; Knittel, JL; Shimomura, ET; Shoemaker, SA; Warren, WS1
Brown, SD; Keasling, R; Peters, JR; Pond, BB1
Chen, TH; Hsu, HY; Wu, SP1
Baumann, MH; Concheiro, M; Dillon-Carter, O; Ellefsen, KN; Elmore, JS; Huestis, MA; Partilla, JS; Rice, KC; Suzuki, M1
Kiyatkin, EA; Ren, SE1
Grecco, GG; Sprague, JE; Zona, LC1
Bortz, A; Heather, E; McDonagh, AM; Shimmon, R1
Aarde, SM; Taffe, MA1
Bastos, ML; Carvalho, F; Carvalho, M; Fernandes, E; Guedes de Pinho, P; Valente, MJ1
Janowsky, A; Miner, NB; O'Callaghan, JP; Phillips, TJ1
Davidson, EJ; Kolakowski, CA; Martin, RJ; Richards, A; Schwartz, DA; Stevens, AD; Yang, IV1
Di Corcia, D; Gerace, E; Palamar, JJ; Salomone, A; Vincenti, M1
Eyer, F; Geith, S; Rabe, C; Romanek, K; Schmoll, S; Schrettl, V; Stenzel, J1
Amaral, C; Bastos, ML; Carvalho, F; Carvalho, M; Correia-da-Silva, G; Duarte, JA; Guedes de Pinho, P; Valente, MJ1
Balíková, M; Dvořáčková, V; Himl, M; Lhotková, E; Linhart, I; Páleníček, T; Židková, M1
Collins, GT; Galindo, KI; Gannon, BM; Mesmin, MP; Rice, KC1
Banks, A; Gao, J; Jiang, G; Lai, FY; Li, J; Mueller, JF; Thai, PK1
Brown, SD; Keasling, R; Kochelek, K; Pond, BB; Strange, LG1
Collins, GT; Galindo, KI; Gannon, BM; Mesmin, MP; Rice, KC; Sulima, A1
Dickerson, TJ; Javadi-Paydar, M; Nguyen, JD; Taffe, MA; Vandewater, SA1
Galettis, P; Martin, J; Williams, M1
Borrull, F; Fontanals, N; Marcé, RM1
Busardò, FP; Giorgetti, R; Marinelli, E; Pantano, F; Pichini, S; Zaami, S1
Chen, Z; Dolan, SB; Gatch, MB; Huang, R1
Hicks, C; Leyrer-Jackson, JM; Muschamp, JW; Olive, MF; Oliver, CF; Rawls, SM; Simmons, SJ1
Calinski, DM; Kisor, DF; Sprague, JE1
Collins, GT; Gannon, BM; Mesmin, MP; Rice, KC; Sulima, A1
Araújo, AM; Cravo, S; de Pinho, PG; Fernandes, C; Pereira, JA; Pinto, MMM; Remião, F; Silva, B1
Baumann, MH; Bukhari, MO; Holy, M; Lehner, KR; Li, Y; Partilla, JS; Saha, K; Sandtner, W; Sitte, HH1
Beck, A; Flockerzi, V; Maurer, HH; Meyer, MR; Richter, LHJ1
Allen, SA; Brown, RW; Oakes, HV; Pond, BB; Tran, LH1
Bouitbir, J; Krähenbühl, S; Liechti, ME; Luethi, D; Sanvee, GM; Zhou, X1
Baumann, MH; Blough, BE; Hoener, MC; Kolaczynska, KE; Liechti, ME; Luethi, D; Rice, KC; Suzuki, M; Walter, M1
Cláudia, M; Eugenia, G; Francisco, CR; Pedro, A; Tiago, R1
Araújo, AM; Bastos, ML; Carvalho, F; Carvalho, M; de Pinho, PG1
Gore, S; Huber, R; Sprague, JE; van Staaden, MJ1
de la Torre, R; Farré, M; Olesti, E; Papaseit, E; Pascual, JA; Pozo, OJ; Ventura, M1
Aresu, L; Bertoni, F; Ferraresso, S; Giannuzzi, D; Giudice, L; Giugno, R; Marconato, L1
Fernandes, C; Guedes de Pinho, P; Remião, F; Silva, B; Silva, R1
Araújo, AM; Bastos, ML; Carvalho, M; Carvalho, T; Castro, A; Valente, MJ; Vaz, I1
Bergman, J; de Moura, FB; Kohut, SJ; Paronis, CA; Prisinzano, TE; Sherwood, A1
Fernandes, C; Guedes de Pinho, P; Palmeira, A; Remião, F; Silva, B; Silva, R1
Bergman, J; Kohut, SJ; Paronis, CA; Prisinzano, TE; Sherwood, AM; Wakeford, AGP1
Bouldin, JB; Brown, SD; Gearlds, C; McKinney, M; Pond, BB; Schreiner, S1
Bailey, JM; Bowman, SK; Cerveny, SE; Huang, S; Jones, RA; Manke, HN; Nelson, KH; Rice, KC; Riley, AL1
Busardò, FP; Di Giorgi, A; Di Trana, A; Farré, M; Lo Faro, AF; Papaseit, E; Pérez-Mañá, C; Pichini, S; Poyatos, L; Sprega, G; Varì, MR; Zaami, S1
Chen, LC; Chen, MC; Chou, D; Hsieh, MC; Lai, CY; Lee, CS; Li, Z; Lin, TB; Peng, HY; Wu, HF1

Reviews

7 review(s) available for methamphetamine and methylone

ArticleYear
GHB and synthetic cathinones: clinical effects and potential consequences.
    Drug testing and analysis, 2011, Volume: 3, Issue:9

    Topics: Alkaloids; Animals; Designer Drugs; Humans; Illicit Drugs; Indans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sodium Oxybate; Substance-Related Disorders

2011
Behavioral pharmacology of designer cathinones: a review of the preclinical literature.
    Life sciences, 2014, Feb-27, Volume: 97, Issue:1

    Topics: Alkaloids; Animals; Benzodioxoles; Central Nervous System Stimulants; Designer Drugs; Drug Evaluation, Preclinical; Humans; Illicit Drugs; Methamphetamine; Pyrrolidines; Substance-Related Disorders; Synthetic Cathinone

2014
The effects and risks associated to mephedrone and methylone in humans: A review of the preliminary evidences.
    Brain research bulletin, 2016, Volume: 126, Issue:Pt 1

    Topics: Animals; Central Nervous System Stimulants; Databases, Bibliographic; Humans; Methamphetamine; Substance-Related Disorders

2016
Predicting the Abuse Liability of Entactogen-Class, New and Emerging Psychoactive Substances via Preclinical Models of Drug Self-administration.
    Current topics in behavioral neurosciences, 2017, Volume: 32

    Topics: Animals; Behavior, Animal; Methamphetamine; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Psychotropic Drugs; Rats; Self Administration; Substance-Related Disorders

2017
Synthetic cathinones related fatalities: an update.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:1

    Topics: Alkaloids; Autopsy; Central Nervous System Stimulants; Death; Fever; Heart Arrest; Humans; Methamphetamine; Substance-Related Disorders

2018
DARK Classics in Chemical Neuroscience: Cathinone-Derived Psychostimulants.
    ACS chemical neuroscience, 2018, 10-17, Volume: 9, Issue:10

    Topics: Alkaloids; Animals; Behavior, Animal; Benzodioxoles; Body Temperature; Catha; Central Nervous System Stimulants; Dopamine; History, 21st Century; History, Medieval; Humans; Locomotion; Methamphetamine; Pyrrolidines; Serotonin; Substance-Related Disorders; Synaptic Transmission; Synthetic Cathinone

2018
A review of the influence of functional group modifications to the core scaffold of synthetic cathinones on drug pharmacokinetics.
    Psychopharmacology, 2019, Volume: 236, Issue:3

    Topics: Alkaloids; Amphetamines; Animals; Designer Drugs; Humans; Methamphetamine; Substance-Related Disorders; Synthetic Drugs

2019

Other Studies

92 other study(ies) available for methamphetamine and methylone

ArticleYear
Inhibition of plasma membrane monoamine transporters by beta-ketoamphetamines.
    European journal of pharmacology, 1999, Sep-17, Volume: 381, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cattle; Cell Membrane; Chromaffin Cells; Dopamine; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Neuropeptides; Norepinephrine; Propiophenones; Serotonin; Tritium; Tumor Cells, Cultured; Vesicular Biogenic Amine Transport Proteins

1999
Methylone and mCPP, two new drugs of abuse?
    Addiction biology, 2005, Volume: 10, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Biogenic Monoamines; Cross-Sectional Studies; Designer Drugs; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Netherlands; Piperazines; Receptors, Serotonin; Serotonin Receptor Agonists; Substance-Related Disorders

2005
Combined intoxication with methylone and 5-MeO-MIPT.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jan-30, Volume: 31, Issue:1

    Topics: Adult; Akathisia, Drug-Induced; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Male; Methamphetamine; Psychoses, Substance-Induced; Substance-Related Disorders; Tryptamines

2007
Metabolism of the recently encountered designer drug, methylone, in humans and rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2006, Volume: 36, Issue:8

    Topics: Adult; Animals; Chromatography, Gas; Chromatography, Liquid; Designer Drugs; Humans; Male; Mass Spectrometry; Methamphetamine; Models, Biological; Molecular Structure; Propiophenones; Rats; Rats, Wistar; Substance Abuse Detection

2006
The disposition into hair of new designer drugs; methylone, MBDB and methcathinone.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Aug-15, Volume: 855, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Gas Chromatography-Mass Spectrometry; Hair; Methamphetamine; Models, Animal; Propiophenones; Rats

2007
Cytotoxic effects of 3,4-methylenedioxy-N-alkylamphetamines, MDMA and its analogues, on isolated rat hepatocytes.
    Archives of toxicology, 2009, Volume: 83, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adenosine Triphosphate; Animals; Cell Death; DNA Damage; Hallucinogens; Hepatocytes; Male; Methamphetamine; Mitochondria, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Oxidative Phosphorylation; Rats; Rats, Inbred F344; Time Factors

2009
[Analysis of designer drugs detected in the products purchased in fiscal year 2006].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:10

    Topics: Chromatography, Liquid; Designer Drugs; Drug and Narcotic Control; Gas Chromatography-Mass Spectrometry; Japan; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methamphetamine; Substance-Related Disorders; Time Factors; Tryptamines

2008
Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry.
    Analytical and bioanalytical chemistry, 2010, Volume: 397, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Designer Drugs; Gas Chromatography-Mass Spectrometry; Humans; Male; Methamphetamine; Rats; Rats, Wistar

2010
Head shop compound abuse amongst attendees of the Drug Treatment Centre Board.
    Irish medical journal, 2010, Volume: 103, Issue:5

    Topics: Chromatography, Liquid; Female; Humans; Illicit Drugs; Ireland; Male; Mass Screening; Mass Spectrometry; Methamphetamine; Piperazines; Substance Abuse Treatment Centers; Substance-Related Disorders

2010
3,4-Methylenedioxymethamphetamine alters left ventricular function and activates nuclear factor-Kappa B (NF-κB) in a time and dose dependent manner.
    International journal of molecular sciences, 2010, Volume: 11, Issue:12

    Topics: Animals; Cell Line; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Enzyme Inhibitors; Methamphetamine; Myocytes, Cardiac; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Rats; Time Factors; Ventricular Function, Left

2010
Seizures and hyponatremia related to ethcathinone and methylone poisoning.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2012, Volume: 8, Issue:1

    Topics: Adult; Alkaloids; Amphetamines; Female; Humans; Hyponatremia; Methamphetamine; Propiophenones; Rhabdomyolysis; Seizures; Selective Serotonin Reuptake Inhibitors; Young Adult

2012
Lethal serotonin syndrome after methylone and butylone ingestion.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2012, Volume: 8, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Fatal Outcome; Female; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin Syndrome; Young Adult

2012
The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Electrochemistry; Hallucinogens; In Vitro Techniques; Locomotion; Male; Membrane Transport Proteins; Methamphetamine; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin; Synaptosomes; Time Factors; Tritium

2012
[A new designer drug: methylone related death].
    Orvosi hetilap, 2012, Feb-19, Volume: 153, Issue:7

    Topics: Adolescent; Amphetamine; Asthma; Autopsy; Causality; Death, Sudden, Cardiac; Designer Drugs; Drug Overdose; Fatal Outcome; Fatty Liver; Heart Defects, Congenital; Humans; Hungary; Male; Methamphetamine; Muscle, Smooth; N-Methyl-3,4-methylenedioxyamphetamine

2012
Bath salts: they are not what you think.
    Journal of psychosocial nursing and mental health services, 2012, Volume: 50, Issue:2

    Topics: Benzodioxoles; Central Nervous System Stimulants; Cross-Sectional Studies; Designer Drugs; Drug and Narcotic Control; Female; Humans; Illicit Drugs; Male; Methamphetamine; Middle Aged; Paranoid Disorders; Psychoses, Substance-Induced; Pyrrolidines; Substance Abuse Detection; Substance-Related Disorders; Synthetic Cathinone

2012
Comparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methylone.
    British journal of pharmacology, 2012, Volume: 167, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Carrier Proteins; Central Nervous System Stimulants; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Ketanserin; Male; Methamphetamine; Mice; Molecular Structure; Motor Activity; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Synaptosomes

2012
Distribution of methylone in four postmortem cases.
    Journal of analytical toxicology, 2012, Volume: 36, Issue:6

    Topics: Adult; Algorithms; Benzodioxoles; Central Nervous System Stimulants; Female; Humans; Liver; Male; Methamphetamine; Pyrrolidines; Synthetic Cathinone; Tissue Distribution; Young Adult

2012
Three fatal intoxications due to methylone.
    Journal of analytical toxicology, 2012, Volume: 36, Issue:6

    Topics: Acidosis; Adult; Central Nervous System Stimulants; Fatal Outcome; Female; Fever; Humans; Illicit Drugs; Male; Methamphetamine; Psychoses, Substance-Induced; Seizures; Young Adult

2012
"Bath salts" and "plant food" products: the experience of one regional US poison center.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:1

    Topics: Adult; Baths; Benzodioxoles; Databases, Factual; Designer Drugs; Dietary Supplements; Female; Humans; Illicit Drugs; Male; Methamphetamine; Middle Aged; North Carolina; Phenethylamines; Plant Preparations; Poison Control Centers; Psychotropic Drugs; Pyrrolidines; Retrospective Studies; Substance Abuse Detection; Substance-Related Disorders; Synthetic Cathinone; Young Adult

2013
"Bath salts"-induced psychosis and serotonin toxicity.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Administration, Inhalation; Adult; Alkaloids; Catha; Central Nervous System Stimulants; Diagnosis, Differential; Emergency Service, Hospital; Female; Humans; Mental Status Schedule; Methamphetamine; Psychoses, Substance-Induced; Pyrrolidines; Serotonin; Serotonin Syndrome

2012
Long-term cognitive and neurochemical effects of "bath salt" designer drugs methylone and mephedrone.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 103, Issue:3

    Topics: Animals; Anxiety; Brain; Depression; Designer Drugs; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Hindlimb Suspension; Male; Maze Learning; Memory Disorders; Methamphetamine; Mice; Mice, Inbred C57BL; Norepinephrine; Radioligand Assay; Rats; Rats, Wistar; Serotonin; Serotonin Plasma Membrane Transport Proteins

2013
Arrays of low-temperature plasma probes for ambient ionization mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2013, Jan-15, Volume: 27, Issue:1

    Topics: Benzodioxoles; Cold Temperature; Illicit Drugs; Limit of Detection; Mass Spectrometry; Methamphetamine; Models, Chemical; Plasma Gases; Pyrrolidines; Reproducibility of Results; Synthetic Cathinone

2013
Sudden cardiac death associated with methylone use.
    The American journal of forensic medicine and pathology, 2013, Volume: 34, Issue:1

    Topics: Alkaloids; Central Nervous System Stimulants; Death, Sudden, Cardiac; Designer Drugs; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Methamphetamine; Molecular Structure; Substance-Related Disorders; Young Adult

2013
Cardiac infection and sepsis in 3 intravenous bath salts drug users.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013, Volume: 56, Issue:11

    Topics: Adult; Alkaloids; Bacteremia; Designer Drugs; Endocarditis, Bacterial; Female; Humans; Illicit Drugs; Male; Methamphetamine; Pericarditis; Staphylococcal Infections; Staphylococcus aureus; Substance Abuse, Intravenous

2013
In vitro metabolism and pharmacokinetic studies on methylone.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:6

    Topics: Animals; Central Nervous System Stimulants; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Humans; Insecta; Methamphetamine; Microsomes, Liver

2013
An integrated pharmacokinetic and pharmacodynamic study of a new drug of abuse, methylone, a synthetic cathinone sold as "bath salts".
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Aug-01, Volume: 45

    Topics: Alkaloids; Animals; Biological Availability; Brain; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Male; Methamphetamine; Motor Activity; Protein Binding; Rats

2013
Identification of novel psychoactive drug use in Sweden based on laboratory analysis--initial experiences from the STRIDA project.
    Scandinavian journal of clinical and laboratory investigation, 2013, Volume: 73, Issue:5

    Topics: Adolescent; Adult; Amphetamines; Benzodiazepines; Cannabinoid Receptor Agonists; Female; Humans; Illicit Drugs; Indoles; Male; Methamphetamine; Middle Aged; Psilocybin; Psychotropic Drugs; Secologanin Tryptamine Alkaloids; Substance-Related Disorders; Sweden; Tryptamines; Young Adult

2013
Acute methylone intoxication in an accidental drowning--a case report.
    Forensic science international, 2013, Sep-10, Volume: 231, Issue:1-3

    Topics: Accidents; Central Nervous System Stimulants; Dronabinol; Drowning; Enzyme-Linked Immunosorbent Assay; Female; Forensic Pathology; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Humans; Liver; Methamphetamine; Solid Phase Extraction; Vitreous Body; Young Adult

2013
Abuse-related and abuse-limiting effects of methcathinone and the synthetic "bath salts" cathinone analogs methylenedioxypyrovalerone (MDPV), methylone and mephedrone on intracranial self-stimulation in rats.
    Psychopharmacology, 2014, Volume: 231, Issue:1

    Topics: Animals; Benzodioxoles; Brain; Conditioning, Operant; Data Interpretation, Statistical; Designer Drugs; Dose-Response Relationship, Drug; Electric Stimulation; Injections; Male; Methamphetamine; Propiophenones; Pyrrolidines; Rats; Rats, Sprague-Dawley; Self Administration; Self Stimulation; Substance-Related Disorders; Synthetic Cathinone

2014
Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds.
    Forensic science international, 2013, Dec-10, Volume: 233, Issue:1-3

    Topics: Benzodioxoles; Cannabinoids; Capsules; Central Nervous System Stimulants; Designer Drugs; Dronabinol; Hallucinogens; Humans; Indoles; Methamphetamine; Methylamines; Molecular Structure; Naphthalenes; Paper; Pentanones; Powders; Pyrrolidines; Substance-Related Disorders; Synthetic Cathinone; Tablets

2013
Repeated doses of methylone, a new drug of abuse, induce changes in serotonin and dopamine systems in the mouse.
    Psychopharmacology, 2014, Volume: 231, Issue:16

    Topics: Animals; CA1 Region, Hippocampal; Cell Survival; Central Nervous System Stimulants; Depression; Dopamine; Dose-Response Relationship, Drug; Fever; Gliosis; Hippocampus; Male; Methamphetamine; Mice; Neostriatum; Neurons; Neurotoxicity Syndromes; Prefrontal Cortex; Serotonin; Swimming; Weight Loss

2014
Mephedrone, methylone and 3,4-methylenedioxypyrovalerone (MDPV) induce conditioned place preference in mice.
    Basic & clinical pharmacology & toxicology, 2014, Volume: 115, Issue:5

    Topics: Amphetamine; Animals; Benzodioxoles; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Pyrrolidines; Synthetic Cathinone

2014
Effects of social interaction and warm ambient temperature on brain hyperthermia induced by the designer drugs methylone and MDPV.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:2

    Topics: Animals; Benzodioxoles; Body Temperature; Brain; Designer Drugs; Disease Models, Animal; Dose-Response Relationship, Drug; Fever; Homeostasis; Interpersonal Relations; Locomotion; Methamphetamine; Psychotropic Drugs; Pyrrolidines; Rats, Long-Evans; Synthetic Cathinone; Temperature; Vasoconstriction

2015
Suspected impaired driving case involving α-pyrrolidinovalerophenone, methylone and ethylone.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Adult; Automobile Driving; Central Nervous System Stimulants; Chromatography, Liquid; Designer Drugs; Humans; Male; Mass Spectrometry; Methamphetamine; Pyrrolidines; Substance Abuse Detection; Substance-Related Disorders; Washington

2014
Serotonergic impairment and memory deficits in adolescent rats after binge exposure of methylone.
    Journal of psychopharmacology (Oxford, England), 2014, Volume: 28, Issue:11

    Topics: Animals; Corpus Striatum; Designer Drugs; Dopamine Plasma Membrane Transport Proteins; Frontal Lobe; Gliosis; Hippocampus; Male; Maze Learning; Memory Disorders; Methamphetamine; Neurotoxicity Syndromes; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Serotonergic Neurons; Serotonin Plasma Membrane Transport Proteins; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

2014
Analysis of the first- and second-generation Raving Dragon Novelty Bath Salts containing methylone and pentedrone.
    Journal of forensic sciences, 2015, Volume: 60 Suppl 1

    Topics: Designer Drugs; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methamphetamine; Methylamines; Pentanones; Spectrophotometry, Infrared

2015
Illnesses and deaths among persons attending an electronic dance-music festival - New York City, 2013.
    MMWR. Morbidity and mortality weekly report, 2014, Dec-19, Volume: 63, Issue:50

    Topics: Adolescent; Adult; Alcohol Drinking; Cocaine; Dancing; Emergency Service, Hospital; Female; Holidays; Humans; Illicit Drugs; Male; Methamphetamine; Music; N-Methyl-3,4-methylenedioxyamphetamine; New York City; Substance-Related Disorders; Young Adult

2014
Crystallographic investigations of select cathinones: emerging illicit street drugs known as `bath salts'.
    Acta crystallographica. Section C, Structural chemistry, 2015, Volume: 71, Issue:Pt 1

    Topics: Alkaloids; Benzaldehydes; Benzodioxoles; Central Nervous System Stimulants; Crystallography, X-Ray; Designer Drugs; Drug Combinations; Humans; Illicit Drugs; Japan; Lidocaine; Methamphetamine; Psychotropic Drugs; Pyrrolidines; Salts; Substance-Related Disorders; Synthetic Cathinone

2015
Intravenous self-administration of mephedrone, methylone and MDMA in female rats.
    Neuropharmacology, 2015, Volume: 92

    Topics: Administration, Intravenous; Animals; Central Nervous System Stimulants; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Hallucinogens; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Time Factors

2015
3,4-Methylenedioxypyrovalerone prevents while methylone enhances methamphetamine-induced damage to dopamine nerve endings: β-ketoamphetamine modulation of neurotoxicity by the dopamine transporter.
    Journal of neurochemistry, 2015, Volume: 133, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzodioxoles; Body Temperature; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Female; Glial Fibrillary Acidic Protein; Methamphetamine; Mice; Mice, Inbred C57BL; Nerve Endings; Neurotoxins; Psychotropic Drugs; Pyrrolidines; Synthetic Cathinone; Tyrosine 3-Monooxygenase

2015
Methylone-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters.
    Behavioural pharmacology, 2015, Volume: 26, Issue:4

    Topics: Animals; Benzazepines; Body Temperature; Central Nervous System Stimulants; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Fever; Male; Methamphetamine; Mice, Knockout; Models, Animal; Raclopride; Receptors, Dopamine D1; Receptors, Dopamine D2; Serotonin Plasma Membrane Transport Proteins

2015
One day access to a running wheel reduces self-administration of D-methamphetamine, MDMA and methylone.
    Drug and alcohol dependence, 2015, Jun-01, Volume: 151

    Topics: Animals; Central Nervous System Stimulants; Drug-Seeking Behavior; Female; Male; Methamphetamine; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Self Administration

2015
Characteristics of the use of 3-MMC and other new psychoactive drugs in Slovenia, and the perceived problems experienced by users.
    The International journal on drug policy, 2016, Volume: 27

    Topics: Adolescent; Adult; Alkaloids; Amphetamine-Related Disorders; Female; Humans; Illicit Drugs; Male; Methamphetamine; Psychotropic Drugs; Slovenia; Surveys and Questionnaires; Young Adult

2016
Death following ingestion of methylone.
    International journal of legal medicine, 2016, Volume: 130, Issue:2

    Topics: Administration, Oral; Bile; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dronabinol; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Humans; Male; Methamphetamine; Psychotropic Drugs; Substance-Related Disorders; Vitreous Body; Young Adult

2016
Intravenous self-administration of entactogen-class stimulants in male rats.
    Neuropharmacology, 2015, Volume: 99

    Topics: Administration, Intravenous; Amphetamine-Related Disorders; Animals; Catheters, Indwelling; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats, Wistar; Self Administration; Sex Characteristics

2015
Reinforcing and neurochemical effects of the "bath salts" constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats.
    Psychopharmacology, 2016, Volume: 233, Issue:10

    Topics: Animals; Benzodioxoles; Cocaine; Dopamine; Male; Methamphetamine; Pyrrolidines; Random Allocation; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Synthetic Cathinone

2016
Detection of "bath salts" and other novel psychoactive substances in hair samples of ecstasy/MDMA/"Molly" users.
    Drug and alcohol dependence, 2016, Apr-01, Volume: 161

    Topics: Adolescent; Adult; Alkaloids; Animals; Drug Users; Female; Hair; Humans; Illicit Drugs; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; New York City; Self Report; Substance-Related Disorders; Surveys and Questionnaires; Tandem Mass Spectrometry; Young Adult

2016
Escalation of intravenous self-administration of methylone and mephedrone under extended access conditions.
    Addiction biology, 2017, Volume: 22, Issue:5

    Topics: Administration, Intravenous; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Male; Methamphetamine; Rats; Rats, Wistar; Self Administration; Time Factors

2017
Cocaine-like discriminative stimulus effects of alpha-pyrrolidinovalerophenone, methcathinone and their 3,4-methylenedioxy or 4-methyl analogs in rhesus monkeys.
    Addiction biology, 2017, Volume: 22, Issue:5

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Discrimination Learning; Dopamine Uptake Inhibitors; Injections, Intramuscular; Macaca mulatta; Male; Methamphetamine; Propiophenones; Pyrrolidines; Reinforcement, Psychology

2017
Case Report of Methylone, Oxymorphone and Ethanol in a Fatality Case with Tissue Distribution.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:7

    Topics: Adult; Drug Overdose; Ethanol; Fatal Outcome; Forensic Toxicology; Humans; Male; Methamphetamine; Oxymorphone; Pulmonary Edema

2016
Quantification of Synthetic Cathinones in Rat Brain Using HILIC-ESI-MS/MS.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:9

    Topics: Alkaloids; Animals; Area Under Curve; Benzodioxoles; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Half-Life; Male; Methamphetamine; Pyrrolidines; Rats; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Substance-Related Disorders; Synthetic Cathinone; Tandem Mass Spectrometry

2016
The detection of multiple illicit street drugs in liquid samples by direct analysis in real time (DART) coupled to Q-orbitrap tandem mass spectrometry.
    Forensic science international, 2016, Volume: 267

    Topics: 4-Butyrolactone; Amphetamines; Beverages; Chromatography, Gas; Humans; Illicit Drugs; Ketamine; Methamphetamine; Nitrazepam; Sodium Oxybate; Tandem Mass Spectrometry

2016
Pharmacokinetic Profiles and Pharmacodynamic Effects for Methylone and Its Metabolites in Rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Male; Methamphetamine; Microdialysis; Rats; Rats, Sprague-Dawley

2017
MDMA, Methylone, and MDPV: Drug-Induced Brain Hyperthermia and Its Modulation by Activity State and Environment.
    Current topics in behavioral neurosciences, 2017, Volume: 32

    Topics: Animals; Antipsychotic Agents; Benzodioxoles; Body Temperature; Brain; Carbazoles; Carvedilol; Central Nervous System Stimulants; Clozapine; Environment; Fever; Humans; Interpersonal Relations; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Propanolamines; Pyrrolidines; Rats; Social Behavior; Synthetic Cathinone; Vasoconstriction; Vasodilator Agents

2017
Cooling down the bath salts: Carvedilol attenuation of methylone and mephedrone mediated hyperthermia.
    Toxicology letters, 2016, Nov-30, Volume: 263

    Topics: Adrenergic beta-Antagonists; Animals; Body Temperature; Carbazoles; Carvedilol; Central Nervous System Stimulants; Designer Drugs; Fever; Male; Methamphetamine; Propanolamines; Rats; Rats, Sprague-Dawley

2016
Organic impurity profiling of methylone and intermediate compounds synthesized from catechol.
    Drug testing and analysis, 2017, Volume: 9, Issue:3

    Topics: Catechols; Central Nervous System Stimulants; Dimerization; Dioxoles; Drug Contamination; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Methamphetamine

2017
Neurotoxicity of β-Keto Amphetamines: Deathly Mechanisms Elicited by Methylone and MDPV in Human Dopaminergic SH-SY5Y Cells.
    ACS chemical neuroscience, 2017, 04-19, Volume: 8, Issue:4

    Topics: Apoptosis; Benzodioxoles; Cell Survival; Central Nervous System Stimulants; Dopaminergic Neurons; Humans; Methamphetamine; Oxidative Stress; Pyrrolidines; Synthetic Cathinone

2017
The combined effects of 3,4-methylenedioxymethamphetamine (MDMA) and selected substituted methcathinones on measures of neurotoxicity.
    Neurotoxicology and teratology, 2017, Volume: 61

    Topics: Animals; Benzodioxoles; Body Temperature Regulation; Corpus Striatum; Dopamine; Glial Fibrillary Acidic Protein; Gliosis; Male; Methamphetamine; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Pyrrolidines; Synthetic Cathinone; Tyrosine 3-Monooxygenase

2017
The Nasal Methylome: A Key to Understanding Allergic Asthma.
    American journal of respiratory and critical care medicine, 2017, 03-15, Volume: 195, Issue:6

    Topics: Administration, Intranasal; Adult; Aged; Asthma; Central Nervous System Stimulants; Diagnosis, Differential; Female; Humans; Male; Methamphetamine; Middle Aged; Nasal Mucosa; Young Adult

2017
Hair Testing for Drugs of Abuse and New Psychoactive Substances in a High-Risk Population.
    Journal of analytical toxicology, 2017, Jun-01, Volume: 41, Issue:5

    Topics: Cyclohexanones; Cyclohexylamines; Hair; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Pentanones; Prevalence; Psychotropic Drugs; Pyrrolidines; Substance Abuse Detection; Substance-Related Disorders

2017
Synthetic cathinones in Southern Germany - characteristics of users, substance-patterns, co-ingestions, and complications.
    Clinical toxicology (Philadelphia, Pa.), 2017, Volume: 55, Issue:6

    Topics: Academic Medical Centers; Adolescent; Adult; Alkaloids; Benzodioxoles; Female; Germany; Hospitalization; Humans; Illicit Drugs; Male; Methamphetamine; Middle Aged; Pyrrolidines; Retrospective Studies; Substance-Related Disorders; Synthetic Cathinone; Young Adult

2017
Methylone and MDPV activate autophagy in human dopaminergic SH-SY5Y cells: a new insight into the context of β-keto amphetamines-related neurotoxicity.
    Archives of toxicology, 2017, Volume: 91, Issue:11

    Topics: Acetylcysteine; Amphetamines; Apoptosis; Autophagy; Benzodioxoles; Cell Line; Central Nervous System Stimulants; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Dose-Response Relationship, Drug; Humans; Methamphetamine; Microtubule-Associated Proteins; Neurotoxicity Syndromes; Oxidative Stress; Pyrrolidines; Synthetic Cathinone

2017
Identification of three new phase II metabolites of a designer drug methylone formed in rats by N-demethylation followed by conjugation with dicarboxylic acids.
    Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:6

    Topics: Animals; Designer Drugs; Dicarboxylic Acids; Male; Methamphetamine; Methylation; Rats; Rats, Wistar

2018
Reinforcing Effects of Binary Mixtures of Common Bath Salt Constituents: Studies with 3,4-Methylenedioxypyrovalerone (MDPV), 3,4-Methylenedioxymethcathinone (methylone), and Caffeine in Rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:4

    Topics: Animals; Behavior, Addictive; Benzodioxoles; Caffeine; Central Nervous System Stimulants; Designer Drugs; Dose-Response Relationship, Drug; Male; Methamphetamine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Synthetic Cathinone

2018
Evaluation of in-sewer transformation of selected illicit drugs and pharmaceutical biomarkers.
    The Science of the total environment, 2017, Dec-31, Volume: 609

    Topics: Biofilms; Biomarkers; Carbamazepine; Codeine; Environmental Monitoring; Illicit Drugs; Ketamine; Methamphetamine; Sewage; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2017
The pharmacokinetic profile of synthetic cathinones in a pregnancy model.
    Neurotoxicology and teratology, 2017, Volume: 63

    Topics: Alkaloids; Animals; Brain; Central Nervous System Stimulants; Female; Methamphetamine; Mice; Pregnancy; Pyrrolidines

2017
Relative reinforcing effects of second-generation synthetic cathinones: Acquisition of self-administration and fixed ratio dose-response curves in rats.
    Neuropharmacology, 2018, 05-15, Volume: 134, Issue:Pt A

    Topics: Analysis of Variance; Animals; Benzodioxoles; Conditioning, Operant; Designer Drugs; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Male; Methamphetamine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Synthetic Cathinone

2018
Locomotor and reinforcing effects of pentedrone, pentylone and methylone in rats.
    Neuropharmacology, 2018, 05-15, Volume: 134, Issue:Pt A

    Topics: Amphetamines; Animals; Body Temperature; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Locomotion; Male; Methamphetamine; Methylamines; Pentanones; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Sex Factors; Telemetry

2018
A Validated Method for the Detection of 32 Bath Salts in Oral Fluid.
    Journal of analytical toxicology, 2017, Oct-01, Volume: 41, Issue:8

    Topics: Alkaloids; Anisoles; Australia; Benzylamines; Dimethoxyphenylethylamine; Humans; Illicit Drugs; Methamphetamine; Pentanones; Phenethylamines; Propiophenones; Psychotropic Drugs; Pyrrolidines; Saliva; Substance Abuse Detection

2017
Solid-phase extraction followed by liquid chromatography-high resolution mass spectrometry to determine synthetic cathinones in different types of environmental water samples.
    Journal of chromatography. A, 2017, Nov-17, Volume: 1524

    Topics: Alkaloids; Chromatography, Liquid; Environmental Monitoring; Fresh Water; Limit of Detection; Methamphetamine; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry; Water Pollutants, Chemical

2017
"Ecstasy" to addiction: Mechanisms and reinforcing effects of three synthetic cathinone analogs of MDMA.
    Neuropharmacology, 2018, 05-01, Volume: 133

    Topics: Animals; Benzazepines; Central Nervous System Stimulants; Conditioning, Operant; Disease Models, Animal; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Drug Combinations; Hallucinogens; HEK293 Cells; Humans; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Serotonin; Substance-Related Disorders

2018
Behavioral economic analysis of the reinforcing effects of "bath salts" mixtures: studies with MDPV, methylone, and caffeine in male Sprague-Dawley rats.
    Psychopharmacology, 2019, Volume: 236, Issue:3

    Topics: Animals; Benzodioxoles; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Economics, Behavioral; Male; Methamphetamine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Synthetic Cathinone

2019
Multi-milligram resolution and determination of absolute configuration of pentedrone and methylone enantiomers.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, Nov-15, Volume: 1100-1101

    Topics: Chromatography, High Pressure Liquid; Circular Dichroism; Methamphetamine; Methylamines; Models, Molecular; Pentanones; Stereoisomerism

2018
The synthetic cathinones, butylone and pentylone, are stimulants that act as dopamine transporter blockers but 5-HT transporter substrates.
    Psychopharmacology, 2019, Volume: 236, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Alkaloids; Amphetamines; Animals; Central Nervous System Stimulants; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Male; Methamphetamine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Synaptosomes; Synthetic Drugs

2019
Cytotoxicity of new psychoactive substances and other drugs of abuse studied in human HepG2 cells using an adopted high content screening assay.
    Toxicology letters, 2019, Volume: 301

    Topics: Acetaminophen; Alkaloids; Biological Assay; Chromatography, Liquid; Fluorescent Dyes; Fluvastatin; Hep G2 Cells; Hepatocytes; Humans; Illicit Drugs; Indans; Indoles; Membrane Potential, Mitochondrial; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Propranolol; Quinolines; Simvastatin; Tandem Mass Spectrometry; Toxicity Tests

2019
Dopaminergic Effects of Major Bath Salt Constituents 3,4-Methylenedioxypyrovalerone (MDPV), Mephedrone, and Methylone Are Enhanced Following Co-exposure.
    Neurotoxicity research, 2019, Volume: 36, Issue:1

    Topics: Animals; Benzodioxoles; Brain; Corpus Striatum; Designer Drugs; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Limbic Lobe; Locomotion; Male; Methamphetamine; Mice; Pyrrolidines; Substantia Nigra; Synthetic Cathinone

2019
Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts.
    International journal of molecular sciences, 2019, Mar-28, Volume: 20, Issue:7

    Topics: Adenosine Triphosphate; Animals; Benzodioxoles; Cell Line; Methamphetamine; Mice; Mitochondria; Myoblasts; Oxygen Consumption; Pentanones; Psychotropic Drugs; Pyrrolidines; Superoxides; Synthetic Cathinone

2019
Metabolites of the ring-substituted stimulants MDMA, methylone and MDPV differentially affect human monoaminergic systems.
    Journal of psychopharmacology (Oxford, England), 2019, Volume: 33, Issue:7

    Topics: Benzodioxoles; Central Nervous System Stimulants; Dopamine; HEK293 Cells; Humans; Membrane Transport Proteins; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Pyrrolidines; Serotonin; Synthetic Cathinone

2019
Determination of New Psychoactive Substances in Whole Blood Using Microwave Fast Derivatization and Gas Chromatography/Mass Spectrometry.
    Journal of analytical toxicology, 2020, Jan-07, Volume: 44, Issue:1

    Topics: Acetone; Alkaloids; Amphetamines; Designer Drugs; Ethylamines; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Methamphetamine; Microwaves; Pentanones; Phenethylamines; Psychotropic Drugs; Pyrrolidines; Substance Abuse Detection

2020
Metabolic signature of methylone in primary mouse hepatocytes, at subtoxic concentrations.
    Archives of toxicology, 2019, Volume: 93, Issue:11

    Topics: Animals; Cell Survival; Cells, Cultured; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Hepatocytes; Metabolome; Metabolomics; Methamphetamine; Mice; Primary Cell Culture

2019
Synthetic cathinones and their phenethylamine analogues produce distinct psychomotor and reward behavior in crayfish.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Alkaloids; Amphetamines; Animals; Astacoidea; Behavior, Animal; Central Nervous System Sensitization; Central Nervous System Stimulants; Conditioning, Psychological; Male; Methamphetamine; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Phenethylamines; Reward

2020
LC-MS/MS method for the quantification of new psychoactive substances and evaluation of their urinary detection in humans for doping control analysis.
    Drug testing and analysis, 2020, Volume: 12, Issue:6

    Topics: Adult; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Doping in Sports; Female; Humans; Illicit Drugs; Limit of Detection; Male; Mass Spectrometry; Methamphetamine; Prospective Studies; Psychotropic Drugs; Reference Standards; Reproducibility of Results; Substance Abuse Detection

2020
Integrated analysis of transcriptome, methylome and copy number aberrations data of marginal zone lymphoma and follicular lymphoma in dog.
    Veterinary and comparative oncology, 2020, Volume: 18, Issue:4

    Topics: Animals; Chromosome Aberrations; DNA Copy Number Variations; Dog Diseases; Dogs; Epigenesis, Genetic; Italy; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Methamphetamine; Transcriptome

2020
Enantioselectivity on the absorption of methylone and pentedrone using Caco-2 cell line: Development and validation of an UHPLC method for cathinones quantification.
    Toxicology and applied pharmacology, 2020, 05-15, Volume: 395

    Topics: Alkaloids; Caco-2 Cells; Chromatography, High Pressure Liquid; Humans; Intestinal Absorption; Methamphetamine; Methylamines; Pentanones; Permeability; Psychotropic Drugs; Sensitivity and Specificity; Stereoisomerism; Structure-Activity Relationship

2020
The interplay between autophagy and apoptosis mediates toxicity triggered by synthetic cathinones in human kidney cells.
    Toxicology letters, 2020, Oct-01, Volume: 331

    Topics: Alkaloids; Apoptosis; Autophagy; Benzodioxoles; Cell Culture Techniques; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Illicit Drugs; Kidney; Methamphetamine; Methylamines; Pentanones; Pyrrolidines; Reactive Nitrogen Species; Reactive Oxygen Species; Synthetic Cathinone; Time Factors

2020
Reinforcing effects of synthetic cathinones in rhesus monkeys: Dose-response and behavioral economic analyses.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 202

    Topics: Alkaloids; Animals; Behavior, Animal; Benzodioxoles; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Pentanones; Protein Binding; Pyrrolidines; Reinforcement, Psychology; Self Administration; Serotonin Plasma Membrane Transport Proteins; Synthetic Cathinone; Synthetic Drugs

2021
S-(+)-Pentedrone and R-(+)-methylone as the most oxidative and cytotoxic enantiomers to dopaminergic SH-SY5Y cells: Role of MRP1 and P-gp in cathinones enantioselectivity.
    Toxicology and applied pharmacology, 2021, 04-01, Volume: 416

    Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Dopaminergic Neurons; Dose-Response Relationship, Drug; Glutathione; Humans; Methamphetamine; Methylamines; Molecular Docking Simulation; Multidrug Resistance-Associated Proteins; Oxidative Stress; Pentanones; Protein Binding; Stereoisomerism

2021
Discriminative-Stimulus Effects of Synthetic Cathinones in Squirrel Monkeys.
    The international journal of neuropsychopharmacology, 2021, 08-20, Volume: 24, Issue:8

    Topics: Alkaloids; Animals; Behavior, Animal; Benzodioxoles; Central Nervous System Stimulants; Discrimination Learning; Interoception; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Propiophenones; Psychotropic Drugs; Pyrrolidines; Saimiri; Synthetic Cathinone

2021
Pharmacokinetics of Synthetic Cathinones Found in Bath Salts in Mouse Brain and Plasma Using High-Pressure Liquid Chromatography-Tandem Mass Spectrometry.
    European journal of drug metabolism and pharmacokinetics, 2021, Volume: 46, Issue:6

    Topics: Alkaloids; Animals; Benzodioxoles; Blood-Testis Barrier; Brain; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Male; Methamphetamine; Mice; Pyrrolidines; Salts; Synthetic Cathinone; Tandem Mass Spectrometry

2021
Methylone pre-exposure differentially impacts the aversive effects of MDPV and MDMA in male and female Sprague-Dawley rats: Implications for abuse vulnerability.
    Pharmacology, biochemistry, and behavior, 2022, Volume: 220

    Topics: Animals; Benzodioxoles; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Substance-Related Disorders

2022
Sweat Testing for the Detection of Methylone after Controlled Administrations in Humans.
    International journal of molecular sciences, 2023, Apr-17, Volume: 24, Issue:8

    Topics: Chromatography, Liquid; Humans; Mass Spectrometry; Methamphetamine; Sweat

2023
Methylone produces antidepressant-relevant actions and prosocial effects.
    Neuropharmacology, 2024, Jan-01, Volume: 242

    Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; Disease Models, Animal; Humans; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Rats; Stress, Psychological

2024