methamphetamine and clozapine

methamphetamine has been researched along with clozapine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.13)18.7374
1990's5 (16.13)18.2507
2000's10 (32.26)29.6817
2010's8 (25.81)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Honma, T; Kitagawa, S1
Davis, L; Papousek, M; Reichinger, M; Reiter, H; Rudolph, M; Rüther, E1
Carlson, KR; Eibergen, RD2
Kelly, PH; Miller, RJ1
Cler, JA; Contreras, PC; Emmett, MR; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL1
Gibb, JW; Gygi, SP; Hanson, GR1
Chaki, S; Kawashima, N; Kumagai, T; Nagamine, M; Nakazato, A; Ogawa, S; Okuyama, S; Suzuki, Y; Tomisawa, K; Yamaguchi, K1
Bunzow, JR; Chester, JA; Dziewczapolski, G; Falzone, TL; Fang, Y; Gershanik, O; Grandy, DK; Larson, JL; Low, MJ; McDougall, JA; Phillips, TJ; Pugsley, TA; Rubinstein, M; Saez, C; Zhang, G1
Chaki, S; Funakoshi, T; Ikeda, Y; Kawashima, N; Kumagai, T; Nagamine, M; Nakazato, A; Ogawa, SI; Okuyama, S; Suzuki, Y; Tomisawa, K; Yoshikawa, R1
Koshiya, K; Morita, T; Nakato, K; Sonoda, R; Wanibuchi, F; Yamaguchi, T1
Kawashima, N; Okuyama, S; Sugiura, H; Suzuki, K; Yamagata, K1
Chaki, S; Funakoshi, T; Goto, M; Kameo, K; Kawashima, N; Kumagai, T; Nakazato, A; Okuyama, S; Suzuki, Y; Yoshikawa, R1
Ishii, S; Nishikawa, T; Sakurai, S; Shimazu, D; Umino, A; Yamamoto, N1
Hashimoto, K; Ishikura, H; Iyo, M; Kishimoto, T; Ozawa, K; Shimizu, E1
Dohniwa, M; Ibi, D; Kamei, H; Mizoguchi, H; Nabeshima, T; Nagai, T; Takuma, K; Yamada, K1
Gross, G; Groth, I; Jongen-Relo, A; Rex, A; Wicke, KM1
Fukakusa, A; Ibi, D; Ito, Y; Kim, HC; Mizoguchi, H; Nakatani, A; Takuma, K; Yamada, K1
Hikichi, H; Maehara, S; Ohta, H; Okuda, S; Satow, A1
Gruber, AJ; Hiyama, H; Huang, B; Jaaro-Peled, H; Kamiya, A; Kohda, K; Kubo, K; Lu, L; Murai, R; Nabeshima, T; Nakajima, K; Niwa, M; Noda, Y; O'Donnell, P; Sawa, A; Seshadri, S; Tomisato, S; Tomita, K1
Inada, K; Ishigooka, J; Kawano, M; Kawano, T; Muraoka, H; Oshibuchi, H; Tsutsumi, T; Yamada, M1
Kiyatkin, EA; Ren, SE1
Cho, EH; Jang, CG; Jeong, JH; Kim, HC; Kim, NH; Lee, YJ; Mai, HN; Nabeshima, T; Nguyen, BT; Nguyen, PT; Sharma, N; Shin, EJ1
Chen, JC; Liao, IM1
Dong, G; Kaibuchi, K; Liao, J; Liu, Y; Mizoguchi, H; Nabeshima, T; Nagai, T; Ozaki, N; Sawahata, M; Wulaer, B; Yamada, K; Zhu, W1
Bousman, CA; Danilewitz, M; Frankow, L; Honer, WG; Mahmood, H; Mathew, N; Poonia, S; Rafizadeh, R; Schütz, CG1

Reviews

1 review(s) available for methamphetamine and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

30 other study(ies) available for methamphetamine and clozapine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Effects of minor tranquilizers and neuroleptics on open-field behavior in rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Butyrophenones; Chlorpromazine; Clozapine; Defecation; Haloperidol; Male; Methamphetamine; Motor Activity; Rats; Thioridazine; Tranquilizing Agents; Trifluperidol

1977
[Pharmacological influence on central serotonergic mechanisms in man and its consequences on sleep (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:6

    Topics: 5-Hydroxytryptophan; Adult; Benserazide; Brain; Clozapine; Female; Humans; Male; Methamphetamine; Middle Aged; Serotonin; Sleep

1976
Dyskinesias in monkeys: interaction of methamphetamine with prior methadone treatment.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methamphetamine; Naloxone; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Stereotyped Behavior

1976
Susceptibility to amphetamine-elicited dyskinesias following chronic methadone treatment in monkeys.
    Annals of the New York Academy of Sciences, 1976, Volume: 281

    Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Drug Interactions; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Macaca mulatta; Male; Methadone; Methamphetamine; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Time Factors

1976
The interaction of neuroleptic and muscarinic agents with central dopaminergic systems.
    British journal of pharmacology, 1975, Volume: 54, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clopenthixol; Clozapine; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Male; Methamphetamine; Models, Biological; Oxotremorine; Parasympathomimetics; Pimozide; Rats; Scopolamine; Substantia Nigra; Thioridazine; Tranquilizing Agents

1975
Clozapine attenuates N-methyl-D-aspartate receptor complex-mediated responses in vivo: tentative evidence for a functional modulation by a noradrenergic mechanism.
    Neuropharmacology, 1991, Volume: 30, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Cerebellum; Clozapine; Cyclic GMP; Dioxanes; Haloperidol; Harmaline; Histamine H2 Antagonists; In Vitro Techniques; Indoles; Injections, Intraventricular; Male; Methamphetamine; Mice; Norepinephrine; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Ritanserin; Serine; Tropisetron

1991
Differential effects of antipsychotic and psychotomimetic drugs on neurotensin systems of discrete extrapyramidal and limbic regions.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Animals; Antipsychotic Agents; Caudate Nucleus; Clozapine; Cocaine; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Extrapyramidal Tracts; Globus Pallidus; Hallucinogens; Haloperidol; Limbic System; Male; Methamphetamine; Neurotensin; Nucleus Accumbens; Rats; Rats, Sprague-Dawley

1994
The atypical antipsychotic profile of NRA0045, a novel dopamine D4 and 5-hydroxytryptamine2A receptor antagonist, in rats.
    British journal of pharmacology, 1997, Volume: 121, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Male; Maze Learning; Methamphetamine; Motor Activity; Pyrrolidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D4; Receptors, Serotonin; Serotonin Antagonists; Thiazoles

1997
Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.
    Cell, 1997, Sep-19, Volume: 90, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Sequence; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Depressants; Clozapine; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Ethanol; Genotype; Humans; Levodopa; Locomotion; Maternal Behavior; Methamphetamine; Mice; Mice, Knockout; Molecular Sequence Data; Motor Activity; Mutagenesis, Site-Directed; Narcotics; Nucleus Accumbens; Receptors, Dopamine D2; Receptors, Dopamine D4; Sensitivity and Specificity; Substantia Nigra; Transcription, Genetic

1997
A selective dopamine D4 receptor antagonist, NRA0160: a preclinical neuropharmacological profile.
    Life sciences, 1999, Volume: 65, Issue:20

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Brain; Catalepsy; Clozapine; Dopamine D2 Receptor Antagonists; Drug Evaluation, Preclinical; Locomotion; Male; Maze Learning; Methamphetamine; Mice; Mice, Inbred ICR; Piperidines; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D4; Reflex, Startle; Stereotyped Behavior; Swimming; Thiazoles

1999
Phencyclidine-induced abnormal behaviors in rats as measured by the hole board apparatus.
    Psychopharmacology, 2000, Volume: 148, Issue:3

    Topics: Alanine; Animals; Behavior, Animal; Clozapine; Dizocilpine Maleate; Male; Methamphetamine; Phencyclidine; Piperazines; Rats; Rats, Wistar

2000
Activation of an effector immediate-early gene arc by methamphetamine.
    Annals of the New York Academy of Sciences, 2000, Volume: 914

    Topics: AIDS-Related Complex; Animals; Autoradiography; Benzazepines; Brain; Central Nervous System Stimulants; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Gene Expression Regulation; Genes, Immediate-Early; Immunohistochemistry; In Situ Hybridization; Male; Methamphetamine; Rats; Rats, Wistar; RNA, Messenger; Time Factors

2000
In vitro and in vivo pharmacological profile of 5-[2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl]-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562), a novel and putative atypical antipsychotic.
    Life sciences, 2002, Aug-09, Volume: 71, Issue:12

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Catalepsy; Central Nervous System Stimulants; Clozapine; Humans; Male; Methamphetamine; Motor Activity; Piperidines; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Drug; Receptors, Serotonin; Risperidone; Stereotyped Behavior; Thiazoles

2002
Effects of psychotomimetic and antipsychotic agents on neocortical and striatal concentrations of various amino acids in the rat.
    Journal of neurochemistry, 2004, Volume: 90, Issue:6

    Topics: Amino Acids; Animals; Antipsychotic Agents; Brain Chemistry; Chromatography, High Pressure Liquid; Clozapine; Corpus Striatum; Drug Interactions; Haloperidol; Male; Methamphetamine; Mixed Function Oxygenases; Neocortex; Rats; Rats, Wistar; Time Factors

2004
Immune activation during pregnancy in mice leads to dopaminergic hyperfunction and cognitive impairment in the offspring: a neurodevelopmental animal model of schizophrenia.
    Biological psychiatry, 2006, Mar-15, Volume: 59, Issue:6

    Topics: Animals; Animals, Newborn; Antibodies, Viral; Brain; Clozapine; Cognition; Cytokines; Disease Models, Animal; Exploratory Behavior; Female; Form Perception; Mental Recall; Methamphetamine; Mice; Mice, Inbred BALB C; Motor Activity; Neural Inhibition; Neuroimmunomodulation; Orientation; Poly I-C; Pregnancy; Pregnancy Complications, Infectious; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Reflex, Startle; Schizophrenia; Virus Diseases

2006
Repeated methamphetamine treatment impairs spatial working memory in rats: reversal by clozapine but not haloperidol.
    Psychopharmacology, 2007, Volume: 194, Issue:1

    Topics: Administration, Oral; Animals; Antipsychotic Agents; Blotting, Western; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Hippocampus; Injections, Subcutaneous; Male; Maze Learning; Memory Disorders; Methamphetamine; Mitogen-Activated Protein Kinase 3; Phosphorylation; Rats; Rats, Wistar; Time Factors

2007
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants.
    Psychopharmacology, 2007, Volume: 195, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine

2007
Improvement by minocycline of methamphetamine-induced impairment of recognition memory in mice.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: Animals; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Exploratory Behavior; Haloperidol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Memory Disorders; Methamphetamine; Mice; Mice, Inbred ICR; Minocycline; Mitogen-Activated Protein Kinase 3; Motor Activity; Neuroprotective Agents; Phosphorylation; Time Factors

2008
Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 91, Issue:1

    Topics: Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Hyperkinesis; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Oxotremorine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenic Psychology

2008
Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits.
    Neuron, 2010, Feb-25, Volume: 65, Issue:4

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Cell Differentiation; Cell Lineage; Chromatography, High Pressure Liquid; Clozapine; Dopamine; Dopamine Agents; Electrophysiology; Exploratory Behavior; Frontal Lobe; Gene Transfer Techniques; Immunohistochemistry; Methamphetamine; Mice; Microdialysis; Motor Activity; Nerve Net; Nerve Tissue Proteins; Neurons; Recognition, Psychology; RNA Interference; Sensory Gating; Spatial Behavior

2010
Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol.
    European journal of pharmacology, 2016, Jun-15, Volume: 781

    Topics: Amygdala; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Cognition; Conditioning, Psychological; Cues; Dopamine; Emotions; Extracellular Space; Fear; Haloperidol; Male; Methamphetamine; Rats; Rats, Sprague-Dawley

2016
MDMA, Methylone, and MDPV: Drug-Induced Brain Hyperthermia and Its Modulation by Activity State and Environment.
    Current topics in behavioral neurosciences, 2017, Volume: 32

    Topics: Animals; Antipsychotic Agents; Benzodioxoles; Body Temperature; Brain; Carbazoles; Carvedilol; Central Nervous System Stimulants; Clozapine; Environment; Fever; Humans; Interpersonal Relations; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Propanolamines; Pyrrolidines; Rats; Social Behavior; Synthetic Cathinone; Vasoconstriction; Vasodilator Agents

2017
Exposure to far-infrared ray attenuates methamphetamine-induced impairment in recognition memory through inhibition of protein kinase C δ in male mice: Comparison with the antipsychotic clozapine.
    Journal of neuroscience research, 2018, Volume: 96, Issue:7

    Topics: Animals; Clozapine; Female; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Infrared Rays; Male; Memory; Methamphetamine; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Kinase C-delta; Recognition, Psychology

2018
Lack of dopamine D4 receptor participation in mouse hyperdopaminergic locomotor response.
    Behavioural brain research, 2021, 01-01, Volume: 396

    Topics: Amphetamine-Related Disorders; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Sensitization; Clozapine; Disease Models, Animal; Dopamine Agents; Locomotion; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Transgenic; Psychotic Disorders; Pyridines; Pyrroles; Receptors, Dopamine D4

2021
Rho kinase inhibitors ameliorate cognitive impairment in a male mouse model of methamphetamine-induced schizophrenia.
    Pharmacological research, 2023, Volume: 194

    Topics: Animals; Clozapine; Cognitive Dysfunction; Haloperidol; Male; Methamphetamine; Mice; Monomeric GTP-Binding Proteins; Protein Kinase Inhibitors; rho-Associated Kinases; Schizophrenia

2023
Association of clozapine treatment and rate of methamphetamine or amphetamine relapses and abstinence among individuals with concurrent schizophrenia spectrum and amphetamine use disorder: A retrospective cohort study.
    Journal of psychopharmacology (Oxford, England), 2023, Volume: 37, Issue:10

    Topics: Amphetamine; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Female; Humans; Male; Methamphetamine; Recurrence; Retrospective Studies; Schizophrenia; Substance-Related Disorders

2023