methamphetamine has been researched along with alpha-synuclein in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (32.35) | 29.6817 |
| 2010's | 13 (38.24) | 24.3611 |
| 2020's | 10 (29.41) | 2.80 |
| Authors | Studies |
|---|---|
| Alessandrí, MG; Fornai, F; Geppert, M; Jahn, R; Schlüter, OM; Südhof, TC; Takamori, S | 1 |
| Battaglia, G; Capobianco, L; De Blasi, A; Ferrucci, M; Fornai, F; Gesi, M; Lazzeri, G; Lenzi, P; Nicoletti, F; Paparelli, A; Soldani, P | 1 |
| Harano, M; Hasegawa, J; Ide, S; Ikeda, K; Inada, T; Iyo, M; Kobayashi, H; Komiyama, T; Ozaki, N; Sekine, Y; Shen, HW; Sora, I; Ujike, H; Yamada, M | 1 |
| Ali, SF; Conneely, OM; Imam, SZ; Jankovic, J; Le, WD; Skinner, JT; Xie, W | 1 |
| Cherng, CG; Hsu, HC; Kuo, YM; Liao, PC; Yu, L | 1 |
| Ebadi, M; Govitrapong, P; Klongpanichapak, S; Sharma, SK | 1 |
| Bandettini Di Poggio, A; De Blasi, A; Fornai, F; Lazzeri, G; Nicoletti, F; Paparelli, A; Ruggieri, S; Soldani, P | 1 |
| Busceti, CI; Fornai, F; Lenzi, P; Mauceli, G; Paparelli, A; Pellegrini, A; Soldani, P | 1 |
| Bruno, V; Busceti, CL; Falleni, A; Ferrucci, M; Fornai, F; Lazzeri, G; Lenzi, P; Paparelli, A | 1 |
| Ajjimaporn, A; Ebadi, M; Govitrapong, P; Phansuwan-Pujito, P | 1 |
| Asanuma, M; Hozumi, H; Kita, T; Miyazaki, I; Takeshima, M; Wagner, GC | 1 |
| Lee, JS; Tavassoly, O | 1 |
| Chen, L; Huang, E; Liu, C; Qiu, P; Wang, H | 1 |
| Ageta-Ishihara, N; Hattori, S; Kinoshita, M; Miyakawa, T; Morita, T; Takahashi, R; Takao, K; Yamakado, H | 1 |
| Chen, CX; Chen, L; Huang, EP; Huang, WY; Liu, C; Qiu, PM; Wang, AF; Wang, HJ; Wu, XF; Xie, WB | 1 |
| Jiang, W; Li, J; Wang, H; Wang, Z; Zhang, Z | 1 |
| Kakish, J; Lee, JS; Tavassoly, O | 1 |
| Ahmadiani, A; Dargahi, L; Valian, N | 1 |
| Celeste Napier, T; Flack, A; Kousik, SM; Moszczynska, A; Persons, AL | 1 |
| Chen, L; Liu, C; Qiao, HH; Qiu, PM; Wang, Y; Wu, XF; Xu, WN; Zhu, LN | 1 |
| Ahmadiani, A; Dargahi, L; Heravi, M; Valian, N | 1 |
| Chen, L; Guan, T; Huang, E; Huang, H; Liang, T; Liu, C; Qu, D; Wang, Q; Xiong, Y; Xu, Y; Yan, L; Yang, J | 1 |
| Biagioni, F; Ferese, R; Fornai, F; Gambardella, S; Lenzi, P; Limanaqi, F; Madonna, M | 1 |
| Chen, L; Ding, J; Li, C; Lian, Y; Meng, Y; Qiu, P; Sun, L | 1 |
| Ding, J; Fan, H; He, Y; Li, C; Lian, Y; Meng, Y; Qiu, P | 1 |
| Ding, J; Fan, H; He, Y; Li, C; Meng, Y; Qiao, H; Qiu, P | 1 |
| Ding, J; He, Y; Hu, S; Huang, J; Li, C; Meng, Y; Qiu, P | 1 |
| Ding, J; He, Y; Huang, J; Li, C; Lian, Y; Meng, Y; Qiu, P; Wang, Y | 1 |
| Ding, J; Fan, H; He, Y; Li, C; Meng, Y; Qiu, P | 1 |
| Su, H; Wu, M; Zhao, M | 1 |
| Desai Bradaric, B; Graves, SM; Kelly, LP; Kousik, SM; Napier, TC; Persons, AL; Yamamoto, BK | 1 |
| Dai, J; Ding, J; Fan, H; Hu, S; Huang, J; Le, C; Li, Z; Qiu, P; Wang, J; Wang, Y; Xia, B | 1 |
| Asadi-Shekaari, M; Askari, R; Haghighi, AH; Keyhani, A; Nabavizadeh, MS; Shafiei, A | 1 |
| Ding, J; Fan, H; Gu, C; He, Y; Huang, J; Li, Y; Qi, X; Qiu, P; Wang, X; Wang, Z; Xie, Q | 1 |
3 review(s) available for methamphetamine and alpha-synuclein
| Article | Year |
|---|---|
Overexpression of alpha-synuclein following methamphetamine: is it good or bad?
Topics: alpha-Synuclein; Animals; Brain; Humans; Inclusion Bodies; Methamphetamine; Mice; Neurons; Rats | 2006 |
[New perspectives on the mechanism of methamphetamine-induced neurotoxicity].
Topics: alpha-Synuclein; Animals; Astrocytes; Corpus Striatum; Cytokines; Dopamine; Dopamine Plasma Membrane Transport Proteins; Free Radicals; Humans; Inflammation; Methamphetamine; Microglia; Oxidative Stress; Self-Injurious Behavior; Substantia Nigra; Vesicular Monoamine Transport Proteins | 2008 |
The Role of α-Synuclein in Methamphetamine-Induced Neurotoxicity.
Topics: alpha-Synuclein; Animals; Central Nervous System Stimulants; Humans; Methamphetamine; Neurotoxicity Syndromes | 2021 |
31 other study(ies) available for methamphetamine and alpha-synuclein
| Article | Year |
|---|---|
Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; alpha-Synuclein; Animals; Antibodies; Blastomeres; Blotting, Southern; Corpus Striatum; Disease Models, Animal; DNA Primers; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Hippocampus; Homovanillic Acid; Humans; Immunoblotting; Immunohistochemistry; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; MPTP Poisoning; Nerve Tissue Proteins; Neurons; Parkinsonian Disorders; Piperazines; Rats; Reserpine; Serotonin; Stem Cells; Subcellular Fractions; Substantia Nigra; Synucleins; Tyrosine 3-Monooxygenase | 2003 |
Methamphetamine produces neuronal inclusions in the nigrostriatal system and in PC12 cells.
Topics: alpha-Methyltyrosine; alpha-Synuclein; Animals; Antioxidants; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Inclusion Bodies; Levodopa; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Microdialysis; Nerve Tissue Proteins; Neurons; PC12 Cells; Rats; Substantia Nigra; Synucleins | 2004 |
Study of association between alpha-synuclein gene polymorphism and methamphetamine psychosis/dependence.
Topics: Adult; alpha-Synuclein; Amphetamine-Related Disorders; Chi-Square Distribution; Female; Gene Frequency; Humans; Male; Methamphetamine; Middle Aged; Monte Carlo Method; Nerve Tissue Proteins; Polymorphism, Genetic; Psychoses, Substance-Induced; Synucleins | 2004 |
Nitric oxide mediates increased susceptibility to dopaminergic damage in Nurr1 heterozygous mice.
Topics: alpha-Synuclein; Animals; Apoptosis Regulatory Proteins; bcl-X Protein; Carrier Proteins; Corpus Striatum; Cytochromes c; DNA Damage; DNA-Binding Proteins; Early Growth Response Protein 1; Male; Methamphetamine; Mice; Mice, Knockout; Mitochondrial Proteins; Nitric Oxide; Nitric Oxide Synthase Type I; Nuclear Receptor Subfamily 4, Group A, Member 2; Proto-Oncogene Proteins c-bcl-2; Transcription Factors; Tumor Suppressor Protein p53 | 2005 |
Local proteins associated with methamphetamine-induced nigrostriatal dopaminergic neurotoxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Animals; Anisomycin; Blotting, Western; Corpus Striatum; Dopamine; Electrophoresis, Gel, Two-Dimensional; Fever; Male; Mass Spectrometry; Methamphetamine; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Neurotoxins; Protein Synthesis Inhibitors; Substantia Nigra; Synucleins; Ubiquitin; Ubiquitin Thiolesterase | 2005 |
Attenuation of cocaine and methamphetamine neurotoxicity by coenzyme Q10.
Topics: alpha-Synuclein; Animals; Central Nervous System Stimulants; Cocaine; Coenzymes; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Electron Transport Complex I; Immunoblotting; Lipid Peroxidation; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Microdialysis; Reactive Oxygen Species; Tyrosine 3-Monooxygenase; Ubiquinone | 2006 |
Convergent roles of alpha-synuclein, DA metabolism, and the ubiquitin-proteasome system in nigrostriatal toxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Methamphetamine; Neurotoxins; Parkinsonian Disorders; PC12 Cells; Proteasome Endopeptidase Complex; Rats; Substantia Nigra; Ubiquitin | 2006 |
Mechanisms involved in the formation of dopamine-induced intracellular bodies within striatal neurons.
Topics: Adrenergic Agents; alpha-Synuclein; Analysis of Variance; Animals; Cells, Cultured; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Inclusion Bodies; Male; Methamphetamine; Mice; Microscopy, Electron, Transmission; Neurons; Oxidopamine; Proteasome Endopeptidase Complex; Rats; Reactive Oxygen Species; Time Factors; Ubiquitin | 2007 |
Zinc protects SK-N-SH cells from methamphetamine-induced alpha-synuclein expression.
Topics: alpha-Synuclein; Cell Line, Tumor; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression; Humans; Methamphetamine; Neuroblastoma; Zinc | 2007 |
Methamphetamine binds to α-synuclein and causes a conformational change which can be detected by nanopore analysis.
Topics: alpha-Synuclein; Binding Sites; Circular Dichroism; Dopaminergic Neurons; Humans; In Vitro Techniques; Lewy Bodies; Lewy Body Disease; Methamphetamine; Models, Molecular; Nanopores; Parkinson Disease; Protein Binding; Protein Conformation; Protein Folding | 2012 |
RNA interference targeting α-synuclein attenuates methamphetamine-induced neurotoxicity in SH-SY5Y cells.
Topics: alpha-Synuclein; Blotting, Western; Cell Line, Tumor; Cell Survival; Central Nervous System Stimulants; Enzyme-Linked Immunosorbent Assay; Gene Knockdown Techniques; Humans; Methamphetamine; Neurons; Parkinson Disease; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA Interference; Transfection | 2013 |
Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice.
Topics: alpha-Synuclein; Animals; Behavior, Animal; Circadian Rhythm; Dopamine; Dopamine Plasma Membrane Transport Proteins; Exploratory Behavior; Humans; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neostriatum; Nerve Degeneration; Parkinson Disease; Peptides; Protein Structure, Quaternary; Rats; Septins; Solubility; Substrate Specificity; Tyrosine 3-Monooxygenase; Ubiquitin-Protein Ligases | 2013 |
S-Nitrosylating protein disulphide isomerase mediates α-synuclein aggregation caused by methamphetamine exposure in PC12 cells.
Topics: alpha-Synuclein; Animals; Apoptosis; Cell Survival; Central Nervous System Stimulants; Enzyme Inhibitors; Gene Knockdown Techniques; Methamphetamine; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; PC12 Cells; Protein Disulfide-Isomerases; Protein Processing, Post-Translational; Rats; RNA Interference; Time Factors; Transfection | 2014 |
Epigenetic upregulation of alpha-synuclein in the rats exposed to methamphetamine.
Topics: alpha-Synuclein; Amphetamine-Related Disorders; Animals; Behavior, Animal; Cytokines; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Humans; Male; Methamphetamine; Methyl-CpG-Binding Protein 2; Parkinson Disease; Promoter Regions, Genetic; Rats; Rats, Wistar; RNA, Messenger; Substantia Nigra; Up-Regulation | 2014 |
Rasagiline, a suicide inhibitor of monoamine oxidases, binds reversibly to α-synuclein.
Topics: alpha-Synuclein; Calorimetry; Indans; Methamphetamine; Monoamine Oxidase Inhibitors; Nanopores; Neuroprotective Agents; Protein Binding; Selegiline | 2015 |
Escalating Methamphetamine Regimen Induces Compensatory Mechanisms, Mitochondrial Biogenesis, and GDNF Expression, in Substantia Nigra.
Topics: alpha-Synuclein; Animals; Glial Cell Line-Derived Neurotrophic Factor; Male; Methamphetamine; Mitochondria; Nuclear Respiratory Factor 1; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Wistar; Substantia Nigra; Transcription Factors; Tyrosine 3-Monooxygenase | 2017 |
Self-administration of methamphetamine alters gut biomarkers of toxicity.
Topics: alpha-Synuclein; Animals; Biomarkers; Colon; Conditioning, Operant; Dopamine beta-Hydroxylase; Male; Methamphetamine; Myenteric Plexus; Rats; Rats, Sprague-Dawley; Self Administration; Tyrosine 3-Monooxygenase; Ubiquitin-Protein Ligases | 2017 |
[Snitrosylating protein disulphide isomerase mediates increased expression of α synuclein caused by methamphetamine in mouse brain].
Topics: alpha-Synuclein; Animals; Brain; Methamphetamine; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Protein Disulfide-Isomerases; Protein Processing, Post-Translational; Random Allocation | 2017 |
Effect of methamphetamine on rat primary midbrain cells; mitochondrial biogenesis as a compensatory response.
Topics: alpha-Synuclein; Animals; Cell Death; Female; Mesencephalon; Methamphetamine; Mitochondria; Neurites; Neurons; Neurotoxicity Syndromes; Organelle Biogenesis; Rats, Wistar | 2019 |
Involvement of C/EBPβ-related signaling pathway in methamphetamine-induced neuronal autophagy and apoptosis.
Topics: alpha-Synuclein; Animals; Apoptosis; Autophagy; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Central Nervous System Stimulants; Gene Expression Regulation; Gene Silencing; Humans; Male; Methamphetamine; Neuroblastoma; Neurons; Rats; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors; Tuberous Sclerosis Complex 2 Protein | 2019 |
Methamphetamine persistently increases alpha-synuclein and suppresses gene promoter methylation within striatal neurons.
Topics: alpha-Synuclein; Animals; Brain; Corpus Striatum; DNA Methylation; Epigenesis, Genetic; Gene Expression; Male; Methamphetamine; Methylation; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Promoter Regions, Genetic | 2019 |
The role of chaperone-mediated autophagy in neurotoxicity induced by alpha-synuclein after methamphetamine exposure.
Topics: alpha-Synuclein; Animals; Cell Line; Central Nervous System Stimulants; Chaperone-Mediated Autophagy; Down-Regulation; HSC70 Heat-Shock Proteins; Humans; Lysosomal-Associated Membrane Protein 2; Methamphetamine; Neurons; Neurotoxicity Syndromes; Protective Factors; Rats; RNA, Small Interfering | 2019 |
The effect of α-synuclein and Tau in methamphetamine induced neurotoxicity in vivo and in vitro.
Topics: alpha-Synuclein; Animals; Behavior, Animal; Cell Line; Central Nervous System Stimulants; Gene Silencing; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxicity Syndromes; Primary Cell Culture; RNA, Small Interfering; tau Proteins | 2020 |
Effect of Parkin on methamphetamine-induced α-synuclein degradation dysfunction in vitro and in vivo.
Topics: alpha-Synuclein; Animals; Cell Line; Cell Line, Tumor; Central Nervous System Stimulants; Humans; Methamphetamine; Mice; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Ubiquitin-Protein Ligases | 2020 |
Alpha-Synuclein deficiency ameliorates chronic methamphetamine induced neurodegeneration in mice.
Topics: alpha-Synuclein; Animals; Autophagy; Axons; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Hippocampus; Lysosomes; Male; Methamphetamine; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Phosphorylation; Substantia Nigra; tau Proteins; Time Factors | 2020 |
Role of alpha-synuclein phosphorylation at Serine 129 in methamphetamine-induced neurotoxicity in vitro and in vivo.
Topics: alpha-Synuclein; Animals; Cell Line; Central Nervous System Stimulants; Humans; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Phosphorylation; Protein Aggregation, Pathological; Serine | 2020 |
Transfer of pathological α-synuclein from neurons to astrocytes via exosomes causes inflammatory responses after METH exposure.
Topics: alpha-Synuclein; Animals; Astrocytes; Cell Line, Tumor; Central Nervous System Stimulants; Coculture Techniques; Cytokines; Exosomes; Hippocampus; Humans; Injections, Intraperitoneal; Male; Methamphetamine; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Nuclear Receptor Subfamily 4, Group A, Member 2; Primary Cell Culture; Synucleinopathies | 2020 |
Gut and brain profiles that resemble pre-motor and early-stage Parkinson's disease in methamphetamine self-administering rats.
Topics: alpha-Synuclein; Animals; Brain; Methamphetamine; Parkinson Disease; Rats; Substantia Nigra | 2021 |
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.
Topics: alpha-Synuclein; Animals; Central Nervous System Stimulants; Gene Expression Regulation; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Neurons; Oligodendroglia | 2021 |
Effects of Moderate-Intensity Interval Training on Gene Expression and Antioxidant Status in the Hippocampus of Methamphetamine-Dependent Rats.
Topics: alpha-Synuclein; Animals; Antioxidants; Cyclin-Dependent Kinase 5; Gene Expression; Hippocampus; Male; Memory Disorders; Methamphetamine; Rats; Rats, Wistar | 2022 |
Transfer of neuron-derived α-synuclein to astrocytes induces neuroinflammation and blood-brain barrier damage after methamphetamine exposure: Involving the regulation of nuclear receptor-associated protein 1.
Topics: alpha-Synuclein; Astrocytes; Blood-Brain Barrier; Central Nervous System Stimulants; Endothelial Cells; Evans Blue; Fluorescein; Glial Cell Line-Derived Neurotrophic Factor; Humans; Immunoglobulin G; Interleukin-6; Methamphetamine; Neuroinflammatory Diseases; Neurons; Neurotoxicity Syndromes; Occludin; Receptors, Cytoplasmic and Nuclear; Tumor Necrosis Factor-alpha | 2022 |