methamphetamine has been researched along with 4-hydroxy-3-methoxymethamphetamine in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (11.76) | 18.2507 |
| 2000's | 21 (61.76) | 29.6817 |
| 2010's | 9 (26.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chei, DM; Foltz, RL; Lim, HK; Zeng, S | 1 |
| Bourquin, D; Bracher, K; Brenneisen, R; Helmlin, HJ; Vonlanthen, D | 1 |
| Kikura, R; Mieczkowski, T; Nakahara, Y; Tagliaro, F | 1 |
| Brenneisen, R; Lanz, M; Thormann, W | 1 |
| Brenneisen, R; Camí, J; de la Torre, R; Farré, M; Mas, M; Ortuño, J; Roset, PN; Segura, J | 1 |
| Camí, J; de la Torre, R; Farré, M; Hernández-López, C; Joglar, J; Llebaria, A; Mas, M; Ortuño, J; Pizarro, N; Pujadas, M; Roset, PN; Segura, J | 1 |
| Cano, S; de la Torre, R; Farré, M; Joglar, J; Llebaria, A; Pizarro, N; Segura, J | 1 |
| de la Torre, R; Farré, M; Joglar, J; Peiró, AM; Pizarro, N; Pujadas, M; Roset, PN | 1 |
| Abraham, TT; Huestis, MA; Pirnay, SO | 1 |
| Abraham, TT; Huestis, MA; Lowe, RH; Pirnay, SO | 1 |
| Cody, JT; Phelix, CF; Valtier, S | 1 |
| Kamata, H; Katagi, M; Nemoto, N; Sakuma, T; Shima, N; Tsuchihashi, H | 1 |
| Maurer, HH; Mueller, M; Peters, FT; Ricaurte, GA | 2 |
| Huestis, MA; Kolbrich, EA; Lowe, RH | 1 |
| Kamata, H; Kamata, T; Katagi, M; Miki, A; Nemoto, N; Nishikawa, M; Sakuma, T; Shima, N; Tsuchihashi, H; Zaitsu, K | 1 |
| Maurer, HH; McCann, UD; Mueller, M; Peters, FT; Ricaurte, GA | 1 |
| Aasim, WR; Gan, SH; Tan, SC | 1 |
| Chaisuwan, P; Jiang, Z; Nacapricha, D; Wilairat, P; William Smith, N | 1 |
| Huestis, MA; Maurer, HH; Mueller, M; Peters, FT; Ricaurte, GA | 1 |
| Huestis, MA; Kolbrich-Spargo, EA; Maurer, HH; Mueller, M; Peters, FT; Ricaurte, GA | 1 |
| Fukuhara, K; Goda, Y; Okuda, H; Shoda, T | 1 |
| Maurer, HH; Meyer, MR; Schwaninger, AE; Zapp, J | 2 |
| Inoue, H; Iwata, YT; Kanamori, T; Kuwayama, K; Miyaguchi, H; Tsujikawa, K | 2 |
| Abraham, TT; Barnes, AJ; Goodwin, RS; Gorelick, DA; Huestis, MA; Kolbrich Spargo, EA; Lowe, RH; Milman, G; Pirnay, SO | 1 |
| Bastos, ML; Branco, P; Carmo, H; Carvalho, F; da Silva, DG; de Pinho, PG; Ferreira, L; Pontes, H; Remião, F | 1 |
| Huestis, MA; Maurer, HH; Meyer, MR; Schwaninger, AE | 1 |
| Maurer, HH; Meyer, MR; Schwaninger, AE | 1 |
| Baumann, MH; Concheiro, M; Huestis, MA; Marrone, GF; Rothman, RB; Scheidweiler, KB | 1 |
| Baumann, MH; Blough, BE; Goldberg, SR; Schindler, CW; Tella, SR; Thorndike, EB | 1 |
| Donzelli, M; Dunand, M; Grouzmann, E; Hysek, CM; Liechti, ME; Rickli, A | 1 |
| Kraemer, T; Liechti, ME; Rickli, A; Schmid, Y; Schmidhauser, C; Steuer, AE | 1 |
4 trial(s) available for methamphetamine and 4-hydroxy-3-methoxymethamphetamine
| Article | Year |
|---|---|
Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS.
Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adolescent; Adult; Chromatography, High Pressure Liquid; Deoxyepinephrine; Female; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hydrolysis; Ion Exchange Resins; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards | 1996 |
Non-linear pharmacokinetics of MDMA ('ecstasy') in humans.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Area Under Curve; Blood Pressure; Cross-Over Studies; Deoxyepinephrine; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Hallucinogens; Humans; Hydrogen-Ion Concentration; Male; Metabolic Clearance Rate; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Pilot Projects; Time Factors | 2000 |
Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis.
Topics: 3,4-Methylenedioxyamphetamine; Deoxyepinephrine; Electrophoresis, Capillary; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Substance Abuse Detection | 2002 |
Chiral Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine and its Phase I and II Metabolites following Controlled Administration to Humans.
Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Methamphetamine; Stereoisomerism; Young Adult | 2015 |
30 other study(ies) available for methamphetamine and 4-hydroxy-3-methoxymethamphetamine
| Article | Year |
|---|---|
Comparative investigation of disposition of 3,4-(methylenedioxy)methamphetamine (MDMA) in the rat and the mouse by a capillary gas chromatography-mass spectrometry assay based on perfluorotributylamine-enhanced ammonia positive ion chemical ionization.
Topics: 3,4-Methylenedioxyamphetamine; Ammonia; Animals; Dopamine; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Male; Methamphetamine; Mice; Mice, Inbred Strains; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Species Specificity | 1992 |
Hair analysis for drug abuse. XV. Disposition of 3, 4-methylenedioxymethamphetamine (MDMA) and its related compounds into rat hair and application to hair analysis for MDMA abuse.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Gas Chromatography-Mass Spectrometry; Hair; Hallucinogens; Humans; Lactates; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Substance Abuse Detection; Substance-Related Disorders | 1997 |
Enantioselective determination of 3,4-methylene-dioxymethamphetamine and two of its metabolites in human urine by cyclodextrin-modified capillary zone electrophoresis.
Topics: 3,4-Methylenedioxyamphetamine; Cyclodextrins; Dopamine; Electrophoresis, Capillary; Humans; Methamphetamine; Molecular Conformation; N-Methyl-3,4-methylenedioxyamphetamine | 1997 |
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites by gas chromatography/mass spectrometry.
Topics: 3,4-Methylenedioxyamphetamine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Methamphetamine; Molecular Conformation; Reference Values; Reproducibility of Results; Substance Abuse Detection | 2003 |
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites in human samples including the catechol-type metabolite (3,4-dihydroxymethamphetamine).
Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Area Under Curve; Catechol O-Methyltransferase; Cytochrome P-450 CYP2D6; Deoxyepinephrine; Half-Life; Humans; Male; Methamphetamine; Methods; Phenotype; Polymorphism, Genetic; Stereoisomerism | 2004 |
Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Calibration; Central Nervous System Stimulants; Dopamine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Substance Abuse Detection | 2006 |
Selection and optimization of hydrolysis conditions for the quantification of urinary metabolites of MDMA.
Topics: 3,4-Methylenedioxyamphetamine; Dopamine; Forensic Toxicology; Glucuronidase; Hallucinogens; Humans; Hydrochloric Acid; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection | 2006 |
Analysis of MDMA and its metabolites in urine and plasma following a neurotoxic dose of MDMA.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Biotransformation; Calibration; Dopamine; Gas Chromatography-Mass Spectrometry; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Psychotropic Drugs; Rats; Reproducibility of Results; Toxicology | 2007 |
Direct determination of glucuronide and sulfate of 4-hydroxy-3-methoxymethamphetamine, the main metabolite of MDMA, in human urine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine-Related Disorders; Calibration; Designer Drugs; Gas Chromatography-Mass Spectrometry; Glucuronides; Hallucinogens; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Sulfates | 2007 |
Validated liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxym
Topics: 3,4-Methylenedioxyamphetamine; Animals; Calibration; Chromatography, Liquid; Deoxyepinephrine; Hallucinogens; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Spectrometry, Mass, Electrospray Ionization | 2007 |
Two-dimensional gas chromatography/electron-impact mass spectrometry with cryofocusing for simultaneous quantification of MDMA, MDA, HMMA, HMA, and MDEA in human plasma.
Topics: 3,4-Methylenedioxyamphetamine; Calibration; Central Nervous System Stimulants; Dopamine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Substance Abuse Detection | 2008 |
Urinary excretion of the main metabolites of 3,4-methylenedioxymethamphetamine (MDMA), including the sulfate and glucuronide of 4-hydroxy-3-methoxymethamphetamine (HMMA), in humans and rats.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Glucuronides; Humans; Male; Mass Spectrometry; Methamphetamine; Rats; Rats, Wistar; Sulfates | 2008 |
Nonlinear pharmacokinetics of (+/-)3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") and its major metabolites in squirrel monkeys at plasma concentrations of MDMA that develop after typical psychoactive doses.
Topics: Animals; Area Under Curve; Deoxyepinephrine; Half-Life; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Species Specificity | 2008 |
Development of a simultaneous liquid-liquid extraction and chiral derivatization method for stereospecific GC-MS analysis of amphetamine-type stimulants in human urine using fractional factorial design.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Substance Abuse Detection | 2008 |
Liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxymethampheta
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Chromatography, Liquid; Deoxyepinephrine; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2008 |
Monolithic and packed particle materials for in-line pre-concentration in capillary electrophoresis for 4-hydroxy-3-methoxy-methamphetamine and terbutaline.
Topics: Benzyl Alcohol; Electrophoresis, Capillary; Methamphetamine; Sensitivity and Specificity; Solid Phase Extraction; Terbutaline | 2008 |
Simultaneous liquid chromatographic-electrospray ionization mass spectrometric quantification of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its metabolites 3,4-dihydroxymethamphetamine, 4-hydroxy-3-methoxymethamphetamine and 3,4-methylenedioxya
Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, Liquid; Deoxyepinephrine; Forensic Toxicology; Hallucinogens; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Spectrometry, Mass, Electrospray Ionization | 2009 |
Hydrolysis of 3,4-methylenedioxymethamphetamine (MDMA) metabolite conjugates in human, squirrel monkey, and rat plasma.
Topics: Animals; Chromatography, Liquid; Deoxyepinephrine; Glucuronic Acid; Glucuronidase; Humans; Hydrolysis; Methamphetamine; Rats; Rats, Sprague-Dawley; Saimiri; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfatases; Sulfuric Acids | 2009 |
4-Hydroxy-3-methoxymethamphetamine glucuronide as a phase II metabolite of 3,4-methylenedioxymethamphetamine: enzyme-assisted synthesis and involvement of human hepatic uridine 5'-diphosphate-glucuronosyltransferase 2B15 in the glucuronidation.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Glucuronates; Glucuronides; Glucuronosyltransferase; Humans; Methamphetamine; Microsomes, Liver; Molecular Structure; Rats | 2009 |
The role of human UDP-glucuronyltransferases on the formation of the methylenedioxymethamphetamine (ecstasy) phase II metabolites R- and S-3-methoxymethamphetamine 4-O-glucuronides.
Topics: Animals; Glucuronides; Glucuronosyltransferase; Humans; Isoenzymes; Male; Methamphetamine; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar | 2009 |
Determination of 4-hydroxy-3-methoxymethamphetamine as a metabolite of methamphetamine in rats and human liver microsomes using gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry.
Topics: Amphetamine; Animals; Bile; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Male; Methamphetamine; Microsomes, Liver; Rats; Rats, Wistar; Tandem Mass Spectrometry | 2009 |
Urinary MDMA, MDA, HMMA, and HMA excretion following controlled MDMA administration to humans.
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Female; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Young Adult | 2009 |
Gas chromatography-ion trap mass spectrometry method for the simultaneous measurement of MDMA (ecstasy) and its metabolites, MDA, HMA, and HMMA in plasma and urine.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Dopamine; Gas Chromatography-Mass Spectrometry; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Sensitivity and Specificity | 2010 |
Sulfation of the 3,4-methylenedioxymethamphetamine (MDMA) metabolites 3,4-dihydroxymethamphetamine (DHMA) and 4-hydroxy-3-methoxymethamphetamine (HMMA) and their capability to inhibit human sulfotransferases.
Topics: Cytosol; Dopamine; Hallucinogens; Humans; Kinetics; Mandelic Acids; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sulfotransferases | 2011 |
Development and validation of LC-HRMS and GC-NICI-MS methods for stereoselective determination of MDMA and its phase I and II metabolites in human urine.
Topics: Chromatography, Liquid; Deoxyepinephrine; Drug Stability; Gas Chromatography-Mass Spectrometry; Glucuronides; Humans; Least-Squares Analysis; Mass Spectrometry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Sulfates | 2011 |
Investigation on the enantioselectivity of the sulfation of the methylenedioxymethamphetamine metabolites 3,4-dihydroxymethamphetamine and 4-hydroxy-3-methoxymethamphetamine using the substrate-depletion approach.
Topics: Chromatography, Gas; Chromatography, Liquid; Humans; Isoenzymes; Kinetics; Lactates; Mandelic Acids; Mass Spectrometry; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sulfates; Sulfotransferases | 2011 |
Interaction of 3,4-methylenedioxymethamphetamine and methamphetamine during metabolism by in vitro human metabolic enzymes and in rats.
Topics: Animals; Biotransformation; Cytochrome P-450 CYP2D6; Cytosol; Drug Interactions; Forensic Toxicology; Hallucinogens; Humans; In Vitro Techniques; Male; Methamphetamine; Microsomes; Monoamine Oxidase; N-Methyl-3,4-methylenedioxyamphetamine; Oxygenases; Rats; Rats, Wistar | 2012 |
Nonlinear pharmacokinetics of (+/-)3,4-methylenedioxymethamphetamine (MDMA) and its pharmacodynamic consequences in the rat.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin | 2014 |
Effects of 3,4-methylenedioxymethamphetamine (MDMA) and its main metabolites on cardiovascular function in conscious rats.
Topics: 3,4-Methylenedioxyamphetamine; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular System; Consciousness; Deoxyepinephrine; Dopamine; Dose-Response Relationship, Drug; Hallucinogens; Heart Rate; Male; Metabolic Detoxication, Phase I; Methamphetamine; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Telemetry; Time Factors | 2014 |
Analytical interference of 4-hydroxy-3-methoxymethamphetamine with the measurement of plasma free normetanephrine by ultra-high pressure liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Healthy Volunteers; Humans; Methamphetamine; Normetanephrine; Tandem Mass Spectrometry | 2014 |