Page last updated: 2024-08-21

methadyl acetate and naloxone

methadyl acetate has been researched along with naloxone in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (72.73)	18.7374
1990's	1 (3.03)	18.2507
2000's	6 (18.18)	29.6817
2010's	2 (6.06)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Horng, JS; Smits, SE; Wong, DT	1
Baskerville, JC; Brands, B; Gowdey, CW; Hirst, M	1
Khazan, N; Steinfels, GF; Young, GA	1
Downs, DA; Wiley, JN	1
Jakubovic, A; McGeer, EG	1
Masten, LW	1
Brocco, MJ; Killam, KF; Robinson, CA	1
Stickney, JL	1
Crofford, MJ; Hui, FW; Smith, AA	1
Chen, RC; Ho, AK	1
Henderson, GL; Rosenkranz, RP	1
Goldstein, A	1
Kauders, F; Schecter, A	1
Henderson, GL; Westkaemper, R	1
Amsterdam, EA; Henderson, GL; Mason, DT; Rendig, SV	1
Dewey, WL	1
Goldstein, A; Judson, BA	1
Kuwahara, MD; Sparber, SB	2
Lichtblau, L; Sparber, SB	2
Burklund, KE; Lichtblau, L; Sparber, SB	1
Goldstein, A; Himmelberger, DU; Judson, BA	1
McGivney, WT; McMillan, DE	1
Bigelow, GE; Buchhalter, AR; Eissenberg, T; Stitzer, ML; Walsh, SL	1
Kreek, MJ; Vocci, FJ	1
Baumgart, MI; Schrott, LM; Sparber, SB; Zhang, X	1
Acri, J; Elkashef, A; Vocci, FJ	1
Arnsten, JH; Gourevitch, MN; Kunins, HV; Whitley, SD	1
Chopra, MP; Feldman, Z; Mancino, MJ; Oliveto, A	1
Amato, L; Davoli, M; Minozzi, S	1
Gewirtz, JC; Hamilton, KL; Harris, AC	1
Amato, L; Bellisario, C; Davoli, M; Minozzi, S	1

Reviews

4 review(s) available for methadyl acetate and naloxone

Article	Year
History and current status of opioid maintenance treatments: blending conference session. Journal of substance abuse treatment, 2002, Volume: 23, Issue:2 Topics: Buprenorphine; Clinical Trials as Topic; History, 20th Century; Humans; Methadone; Methadyl Acetate; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders	2002
Medication development for addictive disorders: the state of the science. The American journal of psychiatry, 2005, Volume: 162, Issue:8 Topics: Animals; Buprenorphine; Chemistry, Pharmaceutical; Clinical Trials as Topic; Cocaine-Related Disorders; Dopamine; Drug Design; Drug Industry; Drug Therapy, Combination; Humans; Methadyl Acetate; Naloxone; National Institutes of Health (U.S.); Opioid-Related Disorders; Program Development; Secondary Prevention; Substance-Related Disorders; United States	2005
Maintenance treatments for opiate dependent adolescent. The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2 Topics: Adolescent; Buprenorphine; Humans; Methadone; Methadyl Acetate; Naloxone; Narcotics; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Young Adult	2009
Maintenance treatments for opiate -dependent adolescents. The Cochrane database of systematic reviews, 2014, Jun-24, Issue:6 Topics: Adolescent; Buprenorphine; Humans; Maintenance Chemotherapy; Methadone; Methadyl Acetate; Naloxone; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Randomized Controlled Trials as Topic	2014

Trials

1 trial(s) available for methadyl acetate and naloxone

Article	Year
Relative potency of levo-alpha-acetylmethadol and methadone in humans under acute dosing conditions. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2 Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Heroin Dependence; Humans; Male; Methadone; Methadyl Acetate; Naloxone; Narcotic Antagonists; Pupil; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Surveys and Questionnaires; Time Factors	1999

Article

Year

Relative potency of levo-alpha-acetylmethadol and methadone in humans under acute dosing conditions.

The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Heroin Dependence; Humans; Male; Methadone; Methadyl Acetate; Naloxone; Narcotic Antagonists; Pupil; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Surveys and Questionnaires; Time Factors

1999

Other Studies

28 other study(ies) available for methadyl acetate and naloxone

Article	Year
The binding of the optical isomers of methadone, alpha-methadol, alpha-acetylmethadol and their N-demethylated derivatives to the opiate receptors of rat brain. Research communications in chemical pathology and pharmacology, 1976, Volume: 14, Issue:4 Topics: Animals; Brain; Dealkylation; Hydromorphone; In Vitro Techniques; Isomerism; Methadone; Methadyl Acetate; Naloxone; Rats; Receptors, Drug	1976
Dependence in rats after one injection of heroin-, LAAM- or hydromorphone-zinc tannate. Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:3 Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Heroin; Heroin Dependence; Humans; Hydromorphone; Methadone; Methadyl Acetate; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders	1979
Spontaneous vs. naloxone-induced abstinence in dependent rats self-administering L-alpha-acetylmethadol (LAAM) or morphine. Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:4 Topics: Animals; Female; Humans; Methadone; Methadyl Acetate; Morphine Dependence; Naloxone; Rats; Self Administration; Sleep, REM; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1979
Naloxone-precipitated jumping in mice pretreated with acute injections of opioids. Life sciences, 1979, Aug-27, Volume: 25, Issue:9 Topics: Animals; Behavior, Animal; Cyclazocine; Dose-Response Relationship, Drug; Enkephalins; Heroin; Male; Methadone; Methadyl Acetate; Mice; Morphine; Naloxone; Narcotics; Pentazocine	1979
Narcotics and rat testicular metabolism. Molecular pharmacology, 1979, Volume: 16, Issue:3 Topics: Animals; Codeine; DNA; Heroin; In Vitro Techniques; Leydig Cells; Male; Methadyl Acetate; Morphine; Naloxone; Narcotics; Protein Biosynthesis; Rats; RNA; Testis; Testosterone	1979
Development of cellular tolerance to lethality and analgesia concurrent with physical dependence following repeated oral administration of LAAM. Drug and alcohol dependence, 1979, Volume: 4, Issue:5 Topics: Administration, Oral; Animals; Drug Tolerance; Humans; Injections, Intraventricular; Lethal Dose 50; Male; Methadone; Methadyl Acetate; Mice; Mice, Inbred ICR; Morphine; Naloxone; Nociceptors; Opioid-Related Disorders	1979
Evaluation of narcotic and narcotic antagonist interactions in primates. Annals of the New York Academy of Sciences, 1976, Volume: 281 Topics: Animals; Cyclazocine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Female; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenytoin; Secobarbital; Self Administration	1976
Cardiac effects of 1-alpha-acetylmethadol. I. Chronotropic effects in vitro. Toxicology and applied pharmacology, 1977, Volume: 40, Issue:1 Topics: Animals; Drug Interactions; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Methacholine Compounds; Methadone; Methadyl Acetate; Morphine; Naloxone; Norepinephrine	1977
Inhibition of growth in young mice treated with d,1-methadone. European journal of pharmacology, 1977, Jun-15, Volume: 43, Issue:4 Topics: Animals; Animals, Newborn; Appetite Depressants; Body Weight; Depression, Chemical; Drug Tolerance; Female; Growth; Levallorphan; Methadone; Methadyl Acetate; Mice; Nalorphine; Naloxone; Reaction Time; Stereoisomerism; Time Factors	1977
Interactions of narcotics, narcotic antagonists, and ethanol during acute, chronic, and withdrawal states. Annals of the New York Academy of Sciences, 1976, Volume: 281 Topics: Alcohol Drinking; Animals; Animals, Newborn; Dextrorphan; Drug Interactions; Ethanol; Humans; Levorphanol; Male; Methadone; Methadyl Acetate; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1976
Renal toxicity of l-alpha-acetylmethadol (LAAM) in the rat. Proceedings of the Western Pharmacology Society, 1975, Volume: 18 Topics: Animals; Hematuria; Kidney Diseases; Kidney Tubules; Methadone; Methadyl Acetate; Morphine; Naloxone; Nephrosis; Phenobarbital; Rats; Time Factors	1975
On the role of chemotherapy in the treatment of heroin addiction. The American journal of drug and alcohol abuse, 1975, Volume: 2, Issue:3-4 Topics: Heroin Dependence; Humans; Methadone; Methadyl Acetate; Motivation; Naloxone; Naltrexone; Substance-Related Disorders	1975
Patient deaths in a narcotic antagonist (naltrexone) and l-alpha-acetylmethadol program. The American journal of drug and alcohol abuse, 1975, Volume: 2, Issue:3-4 Topics: Adult; Heroin Dependence; Homicide; Humans; Male; Methadone; Methadyl Acetate; Naloxone; Naltrexone; Psychotropic Drugs; Substance-Related Disorders; Suicide	1975
Stereotypy following acute administration of l-alpha-acetylmethadol (LAAM) in the rat. Proceedings of the Western Pharmacology Society, 1975, Volume: 18 Topics: Amphetamine; Animals; Apomorphine; Behavior; Drug Interactions; Haloperidol; Humans; Male; Methadone; Methadyl Acetate; Methyltyrosines; Naloxone; Rats; Stereotyped Behavior	1975
Comparative cardiac contractile actions of six narcotic analgesics: morphine, meperidine, pentazocine, fentanyl, methadone and l-alpha-acetylmethadol (LAAM). The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:1 Topics: Analgesics, Opioid; Animals; Cats; Depression, Chemical; Drug Interactions; Fentanyl; Meperidine; Methadone; Methadyl Acetate; Morphine; Myocardial Contraction; Naloxone; Pentazocine; Stimulation, Chemical	1980
Various factors which affect the rate of development of tolerance and physical dependence to abused drugs. NIDA research monograph, 1984, Volume: 54 Topics: Animals; Body Weight; Drug Tolerance; Humans; Methadone; Methadyl Acetate; Morphine; Naloxone; Rats; Reaction Time; Species Specificity; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1984
Naltrexone treatment of heroin addiction: one-year follow-up. Drug and alcohol dependence, 1984, Volume: 13, Issue:4 Topics: Adult; Age Factors; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadyl Acetate; Motivation; Naloxone; Naltrexone	1984
Opiate withdrawal increases ornithine decarboxylase activity which is otherwise unaltered in brains of dependent chicken fetuses. Life sciences, 1983, Jan-31, Volume: 32, Issue:5 Topics: Animals; Brain; Carboxy-Lyases; Chick Embryo; Humans; Methadone; Methadyl Acetate; Naloxone; Ornithine Decarboxylase; Substance Withdrawal Syndrome	1983
Postnatal abstinence or acute toxicity can account for morbidity in developmental studies with opiates. Life sciences, 1983, Sep-19, Volume: 33, Issue:12 Topics: Animals; Animals, Newborn; Body Weight; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Male; Methadone; Methadyl Acetate; Naloxone; Pregnancy; Rats; Rats, Inbred Strains	1983
A method for determining cumulative behavioral toxicity after chronic oral administration of l-alpha-acetylmethadol to female rats. Neurobehavioral toxicology, 1980,Spring, Volume: 2, Issue:1 Topics: Administration, Oral; Animals; Behavior, Animal; Drug Tolerance; Female; Fetus; Humans; Methadone; Methadyl Acetate; Morphine; Naloxone; Rats; Substance-Related Disorders	1980
Opiate withdrawal in utero increases neonatal morbidity in the rat. Science (New York, N.Y.), 1981, May-22, Volume: 212, Issue:4497 Topics: Animals; Drug Tolerance; Embryo Implantation; Female; Fetal Death; Humans; Litter Size; Methadone; Methadyl Acetate; Naloxone; Opioid-Related Disorders; Pregnancy; Pregnancy, Animal; Rats; Substance Withdrawal Syndrome	1981
Prenatal withdrawal from opiates interferes with hatching of otherwise viable chick fetuses. Science (New York, N.Y.), 1981, May-22, Volume: 212, Issue:4497 Topics: Animals; Chick Embryo; Humans; Methadone; Methadyl Acetate; Naloxone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1981
The naloxone test for opiate dependence. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:4 Topics: Humans; Injections, Intramuscular; Injections, Intravenous; Methadyl Acetate; Naloxone; Naltrexone; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome	1980
The effects of levo-alpha-acetylmethadol and its metabolites on schedule-controlled behavior in the pigeon. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 216, Issue:2 Topics: Animals; Behavior, Animal; Columbidae; Drug Tolerance; Methadone; Methadyl Acetate; Naloxone; Structure-Activity Relationship	1981
Prenatal opiate withdrawal activates the chick embryo hypothalamic pituitary-adrenal axis and dilates vitelline blood vessels via serotonin(2) receptors. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Chick Embryo; Corticosterone; Disease Models, Animal; Hypothalamo-Hypophyseal System; Methadyl Acetate; Morphogenesis; Naloxone; Narcotics; Pituitary-Adrenal System; Receptors, Serotonin; Ritanserin; Substance Withdrawal Syndrome	2002
Colocating buprenorphine with methadone maintenance and outpatient chemical dependency services. Journal of substance abuse treatment, 2007, Volume: 33, Issue:1 Topics: Adult; Ambulatory Care; Buprenorphine; Counseling; Delivery of Health Care, Integrated; Female; Health Services Accessibility; Humans; Male; Methadone; Methadyl Acetate; Middle Aged; Naloxone; Narcotics; New York City; Opioid-Related Disorders; Outcome Assessment, Health Care; Patient Care Team; Patient Dropouts; Social Work; Substance Abuse Detection	2007
Sex and opioid maintenance dose influence response to naloxone in opioid-dependent humans: a retrospective analysis. Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:4 Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Methadyl Acetate; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Retrospective Studies; Sex Characteristics; Substance Withdrawal Syndrome	2008
Affective and neuroendocrine effects of withdrawal from chronic, long-acting opiate administration. Brain research, 2013, Nov-13, Volume: 1538 Topics: Affect; Animals; Corticosterone; Male; Methadyl Acetate; Naloxone; Narcotic Antagonists; Narcotics; Neurosecretory Systems; Rats; Rats, Sprague-Dawley; Reflex, Startle; Substance Withdrawal Syndrome	2013