methadone has been researched along with saquinavir in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Berthou, F; Carlhant, D; Dreano, Y; Iribarne, C; Lohezic, F; Picart, D; Riche, C | 1 |
| Erickson, AD; Geletko, SM | 1 |
| Aberg, J; Aweeka, F; D'Amico, R; Flexner, C; Gal, J; Gerber, JG; Gulick, R; Hsu, A; Hughes, V; Mildvan, D; Rosenkranz, S; Segal, Y | 1 |
| Berenson, CS; Buggé, CJ; Cloen, D; de Caprariis, PJ; DiFrancesco, R; Esch, A; Espinosa, O; Hewitt, RG; Ljungqvist, A; Palic, B; Schur, JL; Shelton, MJ | 1 |
| Coles, LD; Eddington, ND; Hassan, HE; Lee, IJ | 1 |
| Jamois, C; Morcos, PN; Morrison, R; Patel, A; Riek, M; Schmitt, C; Smith, P; Zhang, X | 1 |
| Barberan, O; Dubus, E; Ijjaali, I; Petitet, F | 1 |
1 review(s) available for methadone and saquinavir
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for methadone and saquinavir
| Article | Year |
|---|---|
Effect of ritonavir/saquinavir on stereoselective pharmacokinetics of methadone: results of AIDS Clinical Trials Group (ACTG) 401.
Topics: Adult; Drug Interactions; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Methadone; Middle Aged; Narcotics; Ritonavir; Saquinavir; Stereoisomerism; Substance Abuse, Intravenous | 2001 |
The effects of once-daily saquinavir/minidose ritonavir on the pharmacokinetics of methadone.
Topics: Adult; Chromatography, Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; HIV Protease Inhibitors; Humans; Male; Mass Spectrometry; Metabolic Clearance Rate; Methadone; Middle Aged; Narcotics; Ritonavir; Saquinavir; Stereoisomerism; Time Factors | 2004 |
9 other study(ies) available for methadone and saquinavir
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Inhibition of methadone and buprenorphine N-dealkylations by three HIV-1 protease inhibitors.
Topics: Alkylation; Buprenorphine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; HIV Protease Inhibitors; Humans; Indinavir; Kinetics; Methadone; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Ritonavir; Saquinavir | 1998 |
Decreased methadone effect after ritonavir initiation.
Topics: Analgesics, Opioid; Anti-HIV Agents; Diagnosis, Differential; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Male; Methadone; Middle Aged; Ritonavir; Saquinavir; Stavudine; Substance Withdrawal Syndrome; Substance-Related Disorders | 2000 |
Distribution of saquinavir, methadone, and buprenorphine in maternal brain, placenta, and fetus during two different gestational stages of pregnancy in mice.
Topics: Animals; Brain; Buprenorphine; Female; Fetal Development; Fetus; Maternal Exposure; Maternal-Fetal Exchange; Methadone; Mice; Placenta; Pregnancy; Pregnancy, Animal; Saquinavir; Tissue Distribution | 2009 |
Effect of saquinavir/ritonavir (1000/100 mg bid) on the pharmacokinetics of methadone in opiate-dependent HIV-negative patients on stable methadone maintenance therapy.
Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; HIV Protease Inhibitors; HIV Seronegativity; Humans; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Protein Binding; Ritonavir; Saquinavir | 2009 |
Drug repositioning using in silico compound profiling.
Topics: Benzimidazoles; Benzoates; Databases, Factual; Drug Repositioning; Methadone; Receptor, Muscarinic M3; Receptors, Cytoplasmic and Nuclear; Receptors, Gastrointestinal Hormone; Receptors, Neurokinin-2; Receptors, Neuropeptide; Saquinavir; Sirolimus; Telmisartan | 2009 |