methadone has been researched along with rifampin in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (23.08) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 7 (26.92) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bending, MR; Skacel, PO | 1 |
| Kreek, MJ | 1 |
| Bowen, DV; Field, FH; Garfield, JW; Gutjahr, CL; Kreek, MJ | 1 |
| Garfield, JW; Giusti, LM; Gutjahr, CL; Kreek, MJ | 1 |
| Brockmeyer, NH; Goos, M; Mertins, L | 1 |
| Holmes, VF | 1 |
| van Leeuwen, DJ | 1 |
| Baciewicz, AM; Self, TH | 1 |
| Hay, A; Raistrick, D; Wolff, K | 1 |
| Bardou, LG; Berthou, F; Dréano, Y; Iribarne, C; Ménez, JF | 1 |
| Madras, JL; Poujade, F; Saulnier, JL; Schlatter, J | 1 |
| Brazille, P; Bricourt, MO; Deloche, A; Gonzales-Canali, G; Grinda, JM; Mainardi, JL; Piketti, C | 1 |
| Bauer, B; Hartz, AM; Kalvass, JC; Miller, DS; Olson, ER; Pollack, GM; Yang, X; Zhao, R | 1 |
| Allen, KE; Kharasch, ED; Sheffels, P; Totah, RA; Whittington, D | 1 |
| le Polain de W, B | 1 |
| Fang, WB; Lin, SN; Moody, DE; Omiecinski, CJ; Strom, SC; Weyant, DM | 1 |
| Dedicoat, MJ | 1 |
| Dickmann, LJ; Isoherranen, N | 1 |
| Al Zabit, D; Badhan, RKS; Gittins, R | 1 |
| Esmaeili, A; Khodaei, M | 1 |
4 review(s) available for methadone and rifampin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Medical complications in methadone patients.
Topics: Alcoholism; Analgesics; Anesthetics; Blood Proteins; Chronic Disease; Drug Interactions; Ethanol; Hormones; Humans; Immunity; Liver Diseases; Methadone; Prolactin; Respiration; Rifampin; Serum Albumin; Substance-Related Disorders; United States | 1978 |
Drug interactions with methadone.
Topics: Adult; Aged; Chromatography, Gas; Drug Interactions; Feces; Female; Heroin Dependence; Humans; Liver; Male; Mass Spectrometry; Methadone; Methods; Middle Aged; Naloxone; Rifampin; Substance Withdrawal Syndrome; Tuberculosis, Pulmonary | 1976 |
Rifampin drug interactions.
Topics: Anticoagulants; Barbiturates; Contraceptives, Oral; Cytochrome P-450 Enzyme System; Digitoxin; Drug Interactions; Endoplasmic Reticulum; Enzyme Induction; Female; Glucocorticoids; Humans; Hypoglycemic Agents; Male; Methadone; Pregnancy; Quinidine; Rifampin | 1984 |
22 other study(ies) available for methadone and rifampin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Rifampicin and methadone withdrawal.
Topics: Adult; Bronchopneumonia; Drug Interactions; Female; Humans; Methadone; Rifampin; Substance Withdrawal Syndrome; Substance-Related Disorders | 1977 |
Rifampin-induced methadone withdrawal.
Topics: Adult; Aged; Drug Interactions; Heroin Dependence; Humans; Isoniazid; Male; Methadone; Middle Aged; Rifampin; Substance Withdrawal Syndrome; Tuberculosis, Pulmonary | 1976 |
Pharmacokinetic interaction of antimicrobial agents with levomethadon in drug-addicted AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Female; Fusidic Acid; Humans; Male; Methadone; Opioid-Related Disorders; Opportunistic Infections; Prospective Studies; Rifampin; Stereoisomerism; Substance Abuse, Intravenous; Zidovudine | 1991 |
Rifampin-induced methadone withdrawal in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Humans; Male; Methadone; Mycobacterium avium-intracellulare Infection; Opioid-Related Disorders; Rifampin; Substance Abuse, Intravenous; Substance Withdrawal Syndrome | 1990 |
[Rifampicin induces withdrawal symptoms in methadone users].
Topics: Adult; Drug Interactions; Heroin Dependence; Humans; Male; Methadone; Rifampin; Substance Withdrawal Syndrome; Tuberculosis, Cutaneous | 1986 |
Methadone maintenance and tuberculosis treatment.
Topics: Adult; Antibiotics, Antitubercular; Female; Humans; Methadone; Opioid-Related Disorders; Rifampin; Substance Withdrawal Syndrome; Tuberculosis, Pulmonary | 1996 |
Interaction of methadone with substrates of human hepatic cytochrome P450 3A4.
Topics: Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Diazepam; Fluvoxamine; Humans; Methadone; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Rifampin | 1997 |
[Drug interactions with methadone].
Topics: Anticonvulsants; Antitubercular Agents; Antiviral Agents; Drug Interactions; Drug Therapy; Humans; Methadone; Phenytoin; Psychotropic Drugs; Rifampin | 1999 |
Pulmonary homograft endocarditis after Ross procedure.
Topics: Adult; Ampicillin; Aortic Valve; Bioprosthesis; Combined Modality Therapy; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecalis; Gentamicins; Gram-Positive Bacterial Infections; Heart Valve Prosthesis; Hepatitis C, Chronic; HIV Infections; Humans; Male; Methadone; Prosthesis-Related Infections; Pulmonary Valve; Rifampin; Substance Abuse, Intravenous; Transplantation, Autologous | 2004 |
In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation.
Topics: Analgesics; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Dose-Response Relationship, Drug; Drug Interactions; Humans; In Vitro Techniques; Male; Methadone; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pregnane X Receptor; Receptors, Steroid; Rifampin; Up-Regulation | 2006 |
Enantiomeric metabolic interactions and stereoselective human methadone metabolism.
Topics: Algorithms; Aryl Hydrocarbon Hydroxylases; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Induction; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydrazines; Kinetics; Methadone; Mixed Function Oxygenases; Narcotics; Nitrobenzenes; Oxidoreductases, N-Demethylating; Rifampin; Stereoisomerism; Sulfonamides; Superoxides; Thiobarbituric Acid Reactive Substances | 2007 |
Interaction between rifampicin and methadone.
Topics: Drug Interactions; Humans; Methadone; Pain; Rifampin | 2009 |
Effect of rifampin and nelfinavir on the metabolism of methadone and buprenorphine in primary cultures of human hepatocytes.
Topics: Adult; Aged; Analgesics, Opioid; Antibiotics, Antitubercular; Biotransformation; Buprenorphine; Cells, Cultured; Chromatography, Liquid; Dealkylation; Drug Interactions; Female; Glucuronides; Hepatocytes; HIV Protease Inhibitors; Humans; Intestinal Mucosa; Kinetics; Male; Methadone; Microsomes, Liver; Middle Aged; Nelfinavir; Pyrrolidines; Rifampin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Rifampicin reduces methadone concentrations.
Topics: Antibiotics, Antitubercular; Drug Interactions; Humans; Methadone; Narcotics; Opioid-Related Disorders; Rifampin | 2012 |
Quantitative prediction of CYP2B6 induction by estradiol during pregnancy: potential explanation for increased methadone clearance during pregnancy.
Topics: Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bupropion; Carbamazepine; Cells, Cultured; Cytochrome P-450 CYP2B6; Dose-Response Relationship, Drug; Enzyme Induction; Estradiol; Female; Hepatocytes; Humans; Hydroxylation; Metabolic Clearance Rate; Methadone; Oxidoreductases, N-Demethylating; Pregnancy; Primary Cell Culture; Rifampin; RNA, Messenger; Substrate Specificity; Up-Regulation | 2013 |
The optimization of methadone dosing whilst treating with rifampicin: A pharmacokinetic modeling study.
Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Methadone; Middle Aged; Models, Biological; Nucleic Acid Synthesis Inhibitors; Opiate Substitution Treatment; Opioid-Related Disorders; Retrospective Studies; Rifampin | 2019 |
New and Enzymatic Targeted Magnetic Macromolecular Nanodrug System Which Delivers Methadone and Rifampin Simultaneously.
Topics: Animals; Drug Liberation; Humans; Magnetic Phenomena; Magnetite Nanoparticles; Methadone; Rats; Rifampin | 2020 |