methadone and phenobarbital

methadone has been researched along with phenobarbital in 108 studies

Research

Studies (108)

TimeframeStudies, this research(%)All Research%
pre-199068 (62.96)18.7374
1990's7 (6.48)18.2507
2000's11 (10.19)29.6817
2010's15 (13.89)24.3611
2020's7 (6.48)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Liu, SJ; Wang, RI4
Cohen, SN; Neumann, LL1
Di Gregorio, GJ; Knaiz, EK; Nagle, BT; Piraino, AJ1
Ghodse, AH; Mack, JW; Reed, JL1
Evans, DB; Liu, SJ; Wang, RI3
Burstein, Y; Giardina, PJ; Kandall, SR; Peterson, CM; Rausen, AR; Siljestrom, K1
Franklin, MR; Roberts, SM1
Burdock, GA; Hackett, RB; Masten, LW1
Madden, JD1
Lefkowitz, SS; Nemeth, D1
Carlson, KR; Eibergen, RD2
Chappel, JN; Davis, R; Gumpel, J; Madden, JD; Mejia, A; Zuspan, F1
Bauer, J; Gerber, N; Gordon, P; Leger, RM; Lynn, RK; Smith, RG1
Hasegawa, AT; Roerig, DL; Wang, RI3
Burkhalter, A; Masten, LW; Peterson, GR; Way, EL1
Zelson, C2
Keith, LG; Pildes, RS; Vargas, GC; Vidyasagar, D1
Finnegan, LP; Kron, RE; Litt, M1
Greenstein, R; O'Brien, CP; Woody, GE1
Henderson, GL; Rosenkranz, RP1
Eng, D; Finnegan, LP; Kron, RE; Litt, M; Phoenix, MD1
Alexander, GJ1
Breimer, DD; de Boer, AG; van Hoogdalem, E1
Kattner, E1
Calvert, R; Feely, M; Hay, A; Raistrick, D; Wolff, K1
Hinderliter, SA; Sutton, LR1
Burke, WM; Dhopesh, V; Maany, I; Ravi, NV; Woody, GE1
Buckley, PF; Charlton, EJ; Sizemore, WA1
Calzolari, S; Fundaro, C; Mariotti, P; Steffanini, MC; Tempesta, E; Torriolo, MG1
Onofrj, M; Pinto, F; Pola, P; Tempesta, E; Torrioli, MG1
Calabrese, JR; Gulledge, AD1
Kuttab, SH; Nowshad, F; Shargel, L1
Bailey, DN; Jatlow, PI1
Kettner, VR; Lerner, SE; Smith, DE; Wesson, DR1
Julich, H1
Harper, RG; Panepinto, WC; Purow, HM; Sang, E; Solish, GI1
Blatman, S; Lipsitz, PJ1
Kaneto, H; Koida, M; Nakanishi, H; Sasano, H1
Blatman, S1
Baselt, RC; Casarett, LJ1
Frings, CS; Queen, CA1
Pert, CB; Snyder, SH1
Choulis, NH1
Blenman, S; Harper, RG; Sia, CG1
Gartner, LM; Kandall, SR1
Grunberg, E; Klein, B; Sheehan, JE1
Glass, L1
Gould, JB; Rothstein, P1
Alvares, AP; Kappas, A1
Bastos, ML; Chedekel, M; Jukofsky, D; Mulé, SJ; Saffer, E1
Evans, HE; Glass, L1
Harper, RG; Reddy, AM; Stern, G1
Molinengo, L; Ricci-Gamalero, S1
Pálosi, E; Szporny, L1
Novick, DM1
Carin, I; Glass, L; Parekh, A; Solomon, N; Steigman, J; Wong, S1
Freeman, RW; Harbison, RD; James, RC1
Carlson, RK; Little, TL; Tielke, VM1
Bellward, GD; Gontovnick, LS1
Deshpande, JK; Gregory, DF; Tobias, JD1
Ikizler, Y; Koren, G; Selby, P; Theis, JG1
Coyle, MG; Ferguson, A; Lagasse, L; Lester, B; Oh, W1
JACOBSEN, FG; SCHAFII-LASCHTENESCHAI, AH; ZETLER, G1
COLLINS, RJ; MACGREGOR, DW; WEEKS, JR1
BERGER, H1
KRUG, DC; PATRICK, SW; ROSENTHAL, T1
Coyle, MG; Ferguson, A; Lagasse, L; Lester, B; Liu, J1
Donn, SM; Sarkar, S1
Clement-de Boers, A; de Vries, MC; Leeuwenburgh-Pronk, WG1
Baewert, A; Ebner, N; Fischer, G; Jagsch, R; Peternell, A; Rohrmeister, K; Thau, K; Winklbaur, B1
Cheung, KL; Ho, JK; Hon, KL; Hung, EC; Ng, PC1
Ebner, N; Fischer, G; Jung, E; Kopf, N; Thau, K; Winklbaur, B1
Cordero, L; Gardner, DK; Lim, S; Prasad, MR; Samuels, P1
Bastanier, C; Beske, F; Esmaeili, A; Keinhorst, AK; Schlösser, R; Schuster, T1
Bio, LL; Poon, CY; Siu, A1
Becter, ML; Ewald, MB; George, M; Kitzmiller, JP; O'Donell, KA; Salhanick, S1
Crowley, M; Grow, JL; Hall, ES; Jasin, LR; Klebanoff, MA; McClead, RE; Meinzen-Derr, J; Mohan, VK; Stein, H; Walsh, MC; Wexelblatt, SL1
Calpena, AC; Clares, B; Mallandrich, M; Provenza, N; Pueyo, B1
McPherson, C1
Bührer, C; Hüseman, D; Mücke, S; Nagel, M; Siedentopf, J1
Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB1
Cooper, WO; Dudley, J; Maalouf, FI; Patrick, SW; Slaughter, JC1
Jones, HE; Kraft, WK1
MacMillan, KDL1
Bogen, DL; Czynski, AJ; Dansereau, LM; Davis, JM; Engelhardt, B; Hudak, ML; Lester, BM; Marro, P; Oliveira, EL; Shenberger, J; Wachman, EM1
Evrard, CA; Haas, DM; Haneline, LS; Jones, DR; Masters, AR; Metzger, IF; Quinney, SK; Thomas, AE1
Rosenberg, LB1
Brusseau, C; Burnette, T; Heidel, RE1
Adeniyi-Jones, S; Aghai, ZH; Boelig, RC; Carola, D; Greenspan, JS; Kraft, WK; Lafferty, M; Smith, J1
Davey, JG; Martin, J; Osborn, DA; Zankl, A1
Calcaterra, S; Kulick, B; Ray, L; Terasaki, D1

Reviews

15 review(s) available for methadone and phenobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The neonatal narcotic withdrawal syndrome: a therapeutic challenge.
    Clinics in perinatology, 1975, Volume: 2, Issue:1

    Topics: Barbiturates; Chlorpromazine; Diazepam; Humans; Infant Care; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Opium; Phenobarbital; Sleep, REM; Substance Withdrawal Syndrome; Sucking Behavior

1975
The effect of maternal narcotic addiction on the newborn infant.
    Psychological medicine, 1977, Volume: 7, Issue:4

    Topics: Abnormalities, Drug-Induced; Breast Feeding; Female; Fertility; Heroin Dependence; Humans; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Maternal-Fetal Exchange; Menstruation; Methadone; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome

1977
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
    Clinical pharmacokinetics, 1991, Volume: 21, Issue:1

    Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid

1991
[Findings in newborn infants following drug abuse or drug weaning in the mother].
    Der Gynakologe, 1991, Volume: 24, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Female; Fetal Growth Retardation; Heroin Dependence; Humans; Infant, Newborn; Infant, Premature; Methadone; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Pregnancy Complications; Respiratory Insufficiency

1991
The neonatal narcotic abstinence syndrome: a brief review.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1985, Volume: 30, Issue:8

    Topics: Chlorpromazine; Diazepam; Female; Humans; Infant, Newborn; Methadone; Narcotics; Opium; Phenobarbital; Substance Withdrawal Syndrome

1985
Narcotic poisoning of children (1) through accidental ingestion of methadone and (2) in utero.
    Pediatrics, 1974, Volume: 54, Issue:3

    Topics: Administration, Oral; Apgar Score; Birth Weight; Child; Child Care; Female; Gestational Age; Heroin Dependence; Humans; Infant, Newborn; Levallorphan; Maternal-Fetal Exchange; Methadone; Nalorphine; Naloxone; Phenobarbital; Poisoning; Pregnancy; Substance Withdrawal Syndrome; Tablets

1974
Major medical problems and detoxification treatment of parenteral drug-abusing alcoholics.
    Advances in alcohol & substance abuse, 1984,Summer, Volume: 3, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Alcoholism; Homosexuality; Humans; Hypnotics and Sedatives; Infections; Injections, Intravenous; Liver Diseases, Alcoholic; Male; Methadone; Methicillin; Opioid-Related Disorders; Penicillin Resistance; Phenobarbital; Staphylococcus aureus; Substance Withdrawal Syndrome; Substance-Related Disorders

1984
Current management of the neonatal abstinence syndrome: a critical analysis of the evidence.
    Biology of the neonate, 1997, Volume: 71, Issue:6

    Topics: Analgesics, Opioid; Anticonvulsants; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Clonidine; Diazepam; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Infant, Newborn; MEDLINE; Methadone; Morphine; Neonatal Abstinence Syndrome; Opium; Parasympatholytics; Phenobarbital; Sympatholytics

1997
Treating pregnant women dependent on opioids is not the same as treating pregnancy and opioid dependence: a knowledge synthesis for better treatment for women and neonates.
    Addiction (Abingdon, England), 2008, Volume: 103, Issue:9

    Topics: Buprenorphine; Diagnosis, Dual (Psychiatry); Female; GABA Modulators; Humans; Infant, Newborn; Mental Disorders; Methadone; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Pregnancy; Pregnancy Complications

2008
Update on the pharmacologic management of neonatal abstinence syndrome.
    Journal of perinatology : official journal of the California Perinatal Association, 2011, Volume: 31, Issue:11

    Topics: Benzodiazepines; Buprenorphine; Clonidine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Methadone; Narcotics; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy

2011
Pharmacotherapy for Neonatal Abstinence Syndrome: Choosing the Right Opioid or No Opioid at All.
    Neonatal network : NN, 2016, Volume: 35, Issue:5

    Topics: Analgesics; Buprenorphine; Clonidine; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Phenobarbital

2016
Analgesia, Opioids, and Other Drug Use During Pregnancy and Neonatal Abstinence Syndrome.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Breast Feeding; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Clonidine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Kangaroo-Mother Care Method; Maternal-Fetal Exchange; Methadone; Neonatal Abstinence Syndrome; Occupational Therapy; Opiate Substitution Treatment; Opioid-Related Disorders; Pain Management; Patient Education as Topic; Phenobarbital; Physical Therapy Modalities; Pregnancy; Pregnancy Complications; Rooming-in Care

2019
Neonatal Abstinence Syndrome: Review of Epidemiology, Care Models, and Current Understanding of Outcomes.
    Clinics in perinatology, 2019, Volume: 46, Issue:4

    Topics: Analgesics, Opioid; Breast Feeding; Buprenorphine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Nurseries, Hospital; Opiate Substitution Treatment; Opioid-Related Disorders; Parents; Phenobarbital; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rooming-in Care; Severity of Illness Index; Treatment Outcome

2019
Opioid treatment for opioid withdrawal in newborn infants.
    The Cochrane database of systematic reviews, 2021, 07-07, Volume: 7

    Topics: Buprenorphine; Chlorpromazine; Clonidine; Diazepam; Humans; Hypnotics and Sedatives; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Opium; Phenobarbital; Randomized Controlled Trials as Topic

2021

Trials

6 trial(s) available for methadone and phenobarbital

ArticleYear
Measuring compliance in methadone maintenance patients: use of a pharmacologic indicator to "estimate" methadone plasma levels.
    Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Humans; Illicit Drugs; Methadone; Middle Aged; Opioid-Related Disorders; Patient Compliance; Phenobarbital; Treatment Refusal

1991
Neonatal methadone withdrawal. Effect of two treatment regimens.
    American journal of diseases of children (1960), 1983, Volume: 137, Issue:12

    Topics: Blood Pressure; Carbon Dioxide; Drug Administration Schedule; Female; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methadone; Opium; Phenobarbital; Pregnancy; Random Allocation; Respiration; Substance Withdrawal Syndrome; Thyroxine; Time Factors

1983
Diluted tincture of opium (DTO) and phenobarbital versus DTO alone for neonatal opiate withdrawal in term infants.
    The Journal of pediatrics, 2002, Volume: 140, Issue:5

    Topics: Analgesics, Opioid; Drug Therapy, Combination; Heroin; Hospital Costs; Humans; Hypnotics and Sedatives; Infant, Newborn; Length of Stay; Methadone; Neonatal Abstinence Syndrome; Opium; Phenobarbital; Statistics, Nonparametric

2002
Neurobehavioral effects of treatment for opiate withdrawal.
    Archives of disease in childhood. Fetal and neonatal edition, 2005, Volume: 90, Issue:1

    Topics: Analgesics, Opioid; Drug Therapy, Combination; Heroin; Humans; Hypnotics and Sedatives; Infant Behavior; Infant, Newborn; Methadone; Neonatal Abstinence Syndrome; Opium; Phenobarbital; Psychomotor Performance; Treatment Outcome

2005
Management of neonatal abstinence syndrome in neonates born to opioid maintained women.
    Drug and alcohol dependence, 2007, Mar-16, Volume: 87, Issue:2-3

    Topics: Adult; Apgar Score; Female; Gestational Age; Humans; Infant, Newborn; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Patient Selection; Phenobarbital; Pregnancy; Pregnancy Complications

2007
Neurodevelopmental Outcomes of Neonates Randomized to Morphine or Methadone for Treatment of Neonatal Abstinence Syndrome.
    The Journal of pediatrics, 2020, Volume: 219

    Topics: Female; Humans; Infant; Infant, Newborn; Male; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Nervous System; Phenobarbital

2020

Other Studies

87 other study(ies) available for methadone and phenobarbital

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Further study on the correlation of urinary excretion of a methadone metabolite with methadone metabolism and analgesia in the rat.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:4

    Topics: Analgesics; Animals; Dealkylation; Male; Methadone; Phenobarbital; Rats; Time Factors

1979
Secretion of drugs by the parotid glands of rats and human beings.
    Journal of dental research, 1977, Volume: 56, Issue:5

    Topics: Acetylcholine; Adult; Amobarbital; Animals; Barbiturates; Chlorpromazine; Codeine; Glutethimide; Humans; Male; Meprobamate; Methadone; Morphine; Narcotics; Parotid Gland; Pentobarbital; Phenobarbital; Pilocarpine; Rats; Saliva; Secobarbital; Tranquilizing Agents

1977
Analysis and differentiation of mechanism of tolerance to methadone in methadone-fed rats.
    Biochemical pharmacology, 1979, Volume: 28, Issue:2

    Topics: Analgesia; Animals; Drug Tolerance; Male; Methadone; Morphine; Phenobarbital; Rats; Tissue Distribution

1979
Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users.
    The Journal of pediatrics, 1979, Volume: 94, Issue:6

    Topics: Amphetamine; Cocaine; Diazepam; Female; Heroin Dependence; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Morphine Dependence; Phenobarbital; Platelet Aggregation; Substance Withdrawal Syndrome; Substance-Related Disorders; Thrombocytosis

1979
Modification of hepatic microsomal oxidative drug metabolism in rats by the opiate maintenance drugs acetylmethadol, propoxyphene, and methadone.
    Life sciences, 1979, Sep-03, Volume: 25, Issue:10

    Topics: Animals; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Male; Methadone; Methadyl Acetate; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship

1979
Comparison of hepatic microsomal enzyme induction by methadone, phenobarbital and 3-methylcholanthrene in the mouse.
    Biochemical pharmacology, 1979, Dec-01, Volume: 28, Issue:23

    Topics: Animals; Enzyme Induction; In Vitro Techniques; Male; Methadone; Methylcholanthrene; Mice; Mice, Inbred ICR; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Phenobarbital; Sleep

1979
Correlation of urinary excretion of methadone metabolites with methadone metabolism and analgesia in the rat.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 204, Issue:1

    Topics: Analgesics; Animals; Biotransformation; Desipramine; Diazepam; Drug Interactions; Male; Methadone; Phenobarbital; Rats; Reaction Time; Time Factors; Tissue Distribution

1978
Problems pertaining to the care of newborn infants of drug-addicted women.
    The Journal of reproductive medicine, 1978, Volume: 20, Issue:6

    Topics: Apnea; Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Narcotics; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; Substance-Related Disorders; Sucking Behavior; Tremor

1978
Determination of urinary excretion of a methadone metabolite as an indirect measurement of methadone metabolism in the rat.
    Toxicology and applied pharmacology, 1978, Volume: 44, Issue:3

    Topics: Animals; Desipramine; Liver; Male; Methadone; Phenobarbital; Rats; Time Factors

1978
Immunosuppression of rosette-forming cells.
    Advances in experimental medicine and biology, 1976, Volume: 73 Pt B

    Topics: Amphetamine; Animals; Body Weight; Caffeine; Erythrocytes; Humans; Immunity; Immunologic Techniques; Immunosuppression Therapy; Leukocytes; Male; Methadone; Mice; Morphine; Organ Size; Pentobarbital; Phenobarbital; Sheep; Spleen; Substance-Related Disorders

1976
Dyskinesias in monkeys: interaction of methamphetamine with prior methadone treatment.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methamphetamine; Naloxone; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Stereotyped Behavior

1976
Susceptibility to amphetamine-elicited dyskinesias following chronic methadone treatment in monkeys.
    Annals of the New York Academy of Sciences, 1976, Volume: 281

    Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Drug Interactions; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Macaca mulatta; Male; Methadone; Methamphetamine; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Time Factors

1976
Observation and treatment of neonatal narcotic withdrawal.
    American journal of obstetrics and gynecology, 1977, Jan-15, Volume: 127, Issue:2

    Topics: Diazepam; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Phenobarbital; Pregnancy; Substance Withdrawal Syndrome

1977
The metabolism of d-, l- and dl-methadone in the isolated perfused rat liver.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:3

    Topics: Animals; Biotransformation; Half-Life; Isomerism; Liver; Methadone; Perfusion; Phenobarbital; Proadifen; Rats

1977
Effect of alteration of metabolism on the analgesic activity, toxicity, distribution and excretion of l-alpha-acetylmethadol in the rat.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:2

    Topics: Analgesics; Animals; Bile; Feces; Lethal Dose 50; Liver; Male; Methadone; Methadyl Acetate; Phenobarbital; Rats; Tissue Distribution

1977
Role of metabolism in the biliary excretion of methadone metabolites.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:1

    Topics: Animals; Bile; Isotope Labeling; Male; Methadone; Phenobarbital; Pyrrolidines; Rats; Time Factors

1976
Microsomal enzyme induction by methadone and its implications on tolerance to methodone lethality.
    Nature, 1975, Jan-17, Volume: 253, Issue:5488

    Topics: Animals; Biotransformation; Drug Tolerance; Enzyme Induction; Lethal Dose 50; Liver; Methadone; Mice; Microsomes, Liver; Morphine; Organ Size; Oxidoreductases, N-Demethylating; Phenobarbital; Proteins

1975
Effect of phenobarbital pretreatment on the metabolism and biliary excretion of methadone.
    Biochemical pharmacology, 1975, Feb-01, Volume: 24, Issue:3

    Topics: Animals; Bile; Dealkylation; Glucuronates; Male; Methadone; Microsomes, Liver; Phenobarbital; Rats; Time Factors

1975
Acute management of neonatal addiction.
    Addictive diseases, 1975, Volume: 2, Issue:1-2

    Topics: Antidiarrheals; Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Phenobarbital; Pregnancy; Pregnancy Complications; Seizures; Sleep Wake Disorders; Substance Withdrawal Syndrome; Vomiting; Water-Electrolyte Balance

1975
Effect of maternal heroin addiction on 67 liveborn neonates. Withdrawal symptoms, small body size, and small head circumference were frequent findings.
    Clinical pediatrics, 1975, Volume: 14, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Birth Weight; Blood Glucose; Cephalometry; Chlorpromazine; Female; Hematocrit; Hemorrhage; Heroin Dependence; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Newborn, Diseases; Jaundice, Neonatal; Male; Maternal-Fetal Exchange; Methadone; Phenobarbital; Pregnancy; Respiratory Distress Syndrome, Newborn; Substance Withdrawal Syndrome

1975
Narcotic addiction in the newborn: differences in behavior generated by methadone and heroin.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adaptation, Physiological; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Opium; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; Substance-Related Disorders; Sucking Behavior

1975
Misuse and abuse of diazepam: an increasingly common medical problem.
    The International journal of the addictions, 1975, Volume: 10, Issue:5

    Topics: Adult; Diazepam; Drug Prescriptions; Heroin Dependence; Humans; Legislation, Drug; Male; Methadone; Phenobarbital; Substance Withdrawal Syndrome; Substance-Related Disorders; United States

1975
Renal toxicity of l-alpha-acetylmethadol (LAAM) in the rat.
    Proceedings of the Western Pharmacology Society, 1975, Volume: 18

    Topics: Animals; Hematuria; Kidney Diseases; Kidney Tubules; Methadone; Methadyl Acetate; Morphine; Naloxone; Nephrosis; Phenobarbital; Rats; Time Factors

1975
Increased analgesia and alterations in distribution and metabolism of methadone by desipramine in the rat.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:1

    Topics: Analgesia; Animals; Brain; Desipramine; Drug Synergism; In Vitro Techniques; Kidney; Lethal Dose 50; Liver; Lung; Male; Methadone; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Reaction Time; Time Factors

1975
Neonatal narcotic abstinence: Effects of pharmacotherapeutic agents and maternal drug usage on nutritive sucking behavior.
    The Journal of pediatrics, 1976, Volume: 88, Issue:4 Pt 1

    Topics: Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Methadone; Opium; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; Sucking Behavior

1976
Direct use of ion-exchange papers in hemagglutination-inhibition tests for drug abuse.
    Clinical chemistry, 1976, Volume: 22, Issue:7

    Topics: Aspirin; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Paper; Codeine; Hemagglutination Inhibition Tests; Humans; Methadone; Morphine; Nicotine; Phenobarbital; Substance-Related Disorders

1976
Diazepam abuse in pregnant women on methadone maintenance. Implications for the neonate.
    Clinical pediatrics, 1990, Volume: 29, Issue:2

    Topics: Adult; Diazepam; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Methadone; Opium; Parasympatholytics; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1990
Detoxification with phenobarbital of alprazolam-dependent polysubstance abusers.
    Journal of substance abuse treatment, 1990, Volume: 7, Issue:1

    Topics: Adult; Alprazolam; Combined Modality Therapy; Follow-Up Studies; Humans; Illicit Drugs; Male; Methadone; Opioid-Related Disorders; Phenobarbital; Substance-Related Disorders

1990
Medication management in patients with chronic non-malignant pain. A review of the use of a drug withdrawal protocol.
    Pain, 1986, Volume: 26, Issue:2

    Topics: Analgesics, Opioid; Chronic Disease; Drug Combinations; Humans; Hypnotics and Sedatives; Methadone; Pain; Phenobarbital; Retrospective Studies; Substance Withdrawal Syndrome; Substance-Related Disorders; Therapeutic Equivalency

1986
The influence of pharmacotherapy on the neonatal sleep patterns of infants born to opiate-addicted mothers.
    NIDA research monograph, 1987, Volume: 76

    Topics: Drug Therapy, Combination; Female; Humans; Infant, Newborn; Male; Methadone; Narcotics; Neonatal Abstinence Syndrome; Phenobarbital; Sleep

1987
Fetal addiction to methadone: postnatal abstinence syndrome and development of visual evoked potentials.
    Drug and alcohol dependence, 1986, Volume: 18, Issue:1

    Topics: Animals; Electroencephalography; Evoked Potentials, Visual; Female; Maternal-Fetal Exchange; Methadone; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1986
Effect of phenobarbital pretreatment on the plasma and urinary levels of (-)-alpha-acetylmethadol and its metabolites.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:3

    Topics: Animals; Biotransformation; Chromatography, Thin Layer; Injections, Intraperitoneal; Male; Methadone; Methadyl Acetate; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors

1985
Methaqualone overdose: analytical methodology, and the significance of serum drug concentrations.
    Clinical chemistry, 1973, Volume: 19, Issue:6

    Topics: Alcohol Drinking; Alkanes; Chloroform; Chromatography, Gas; Chromatography, Thin Layer; Consciousness; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Histamine H1 Antagonists; Humans; Methadone; Methaqualone; Phenobarbital; Salicylamides; Scopolamine; Solubility; Spectrophotometry, Ultraviolet; Substance-Related Disorders

1973
Treatment of polydrug users in San Francisco.
    The American journal of drug and alcohol abuse, 1974, Volume: 1, Issue:2

    Topics: Adult; Aftercare; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; California; Crisis Intervention; Female; Financing, Government; Heroin Dependence; Hospitalization; Humans; Male; Methadone; MMPI; Phenobarbital; Psychotherapy; Substance-Related Disorders; Therapeutic Community

1974
Infant of the addicted mother.
    The New England journal of medicine, 1973, Jun-28, Volume: 288, Issue:26

    Topics: Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methadone; Phenobarbital; Pregnancy; Pregnancy Complications; Sleep, REM; Substance Withdrawal Syndrome; Substance-Related Disorders

1973
[Further studies on the effect of various drugs on the respiration].
    Allergie und Asthma, 1968, Volume: 14, Issue:5

    Topics: Antifibrinolytic Agents; Benzoates; Central Nervous System Stimulants; Chlorpromazine; Humans; Meperidine; Methadone; Phenobarbital; Pulmonary Heart Disease; Respiration; Theobromine

1968
The effect of a methadone treatment program upon pregnant heroin addicts and their newborn infants.
    Pediatrics, 1974, Volume: 54, Issue:3

    Topics: Adult; Birth Weight; Blood Glucose; Calcium; Female; Fetus; Gestational Age; Heroin Dependence; Humans; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Male; Maternal-Fetal Exchange; Methadone; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome

1974
Newborn infants of mothers on methadone maintenance.
    New York state journal of medicine, 1974, Volume: 74, Issue:6

    Topics: Body Weight; Camphor; Diazepam; Female; Gestational Age; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Methadone; Opium; Parents; Phenobarbital; Substance Withdrawal Syndrome; Substance-Related Disorders

1974
A scoring system for abstinence syndrome in morphine dependent mice and application to evaluate morphine type dependence liability of drugs.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:5

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Humans; Male; Meperidine; Methadone; Mice; Morphine Dependence; Phenobarbital; Substance Withdrawal Syndrome; Time Factors

1973
Biliary and urinary elimination of methadone and its metabolites in the rat.
    Biochemical pharmacology, 1972, Oct-15, Volume: 21, Issue:20

    Topics: Administration, Oral; Animals; Bile; Chromatography, Gas; Chromatography, Thin Layer; Injections, Intravenous; Injections, Subcutaneous; Kinetics; Male; Methadone; Phenobarbital; Pyrrolidines; Rats; Time Factors; Tritium

1972
Stability of certain drugs of abuse in urine specimens.
    Clinical chemistry, 1972, Volume: 18, Issue:11

    Topics: Amphetamine; Azides; Cocaine; Codeine; Drug Stability; Humans; Methadone; Morphine; Pharmaceutical Preparations; Phenobarbital; Secobarbital; Substance-Related Disorders; Temperature

1972
Opiate receptor: demonstration in nervous tissue.
    Science (New York, N.Y.), 1973, Mar-09, Volume: 179, Issue:4077

    Topics: Analgesics; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Codeine; Colchicine; Dextromethorphan; Dextropropoxyphene; Guinea Pigs; Histamine; Intestinal Mucosa; Levallorphan; Methadone; Mice; Morphine; Nalorphine; Naloxone; Phenazocine; Phenobarbital; Rats; Receptors, Drug; Serotonin; Tritium

1973
Treatment of neonatal withdrawal syndrome.
    The Medical letter on drugs and therapeutics, 1973, May-25, Volume: 15, Issue:11

    Topics: Chlorpromazine; Diazepam; Heroin Dependence; Humans; Infant, Newborn; Methadone; Opium; Phenobarbital; Substance Withdrawal Syndrome

1973
Separation and quantitation of mixtures of the most commonly abused drugs.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:1

    Topics: Amobarbital; Cannabis; Chromatography, Thin Layer; Dextroamphetamine; Ephedrine; Humans; Indicators and Reagents; Lysergic Acid Diethylamide; Methadone; Methamphetamine; Methods; Morphine; Opium; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Secobarbital; Solvents; Spectrophotometry, Ultraviolet; Substance-Related Disorders

1973
Observations on the sudden death of infants born to addicted mothers.
    Proceedings. National Conference on Methadone Treatment, 1973, Volume: 2

    Topics: Adult; Death, Sudden; Female; Heroin Dependence; Humans; Infant; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Male; Maternal-Fetal Exchange; Methadone; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; United States

1973
Late presentation of drug withdrawal symptoms in newborns.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:1

    Topics: Birth Weight; Camphor; Diazepam; Female; Gestational Age; Heroin Dependence; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methadone; Opium; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; Substance-Related Disorders

1974
Use of fluorescamine ("Fluram") to detect amphetamine in urine by thin-layer chromatography.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amphetamine; Benzofurans; Chromatography, Ion Exchange; Chromatography, Thin Layer; Drug Stability; Evaluation Studies as Topic; Fluorescence; Glutethimide; Humans; Indicators and Reagents; Methadone; Methamphetamine; Methods; Microchemistry; Morphine; Pentobarbital; Phenobarbital; Phenothiazines; Quinine; Spiro Compounds; Substance-Related Disorders; Time Factors

1974
Narcotic withdrawal in the newborn infant.
    Journal of the National Medical Association, 1974, Volume: 66, Issue:2

    Topics: Diazepam; Female; Fetus; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methadone; Opium; Phenobarbital; Pregnancy; Pregnancy Complications; Prenatal Care; Substance Withdrawal Syndrome; Substance-Related Disorders

1974
Born with a habit. Infants of drug-addicted mothers.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Barbiturates; Camphor; Chlorpromazine; Codeine; Diazepam; Female; Fetus; Heroin; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal Age; Methadone; Opium; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; Substance-Related Disorders

1974
Influence of phenobarbital on the metabolism and analgesic effect of methadone in rats.
    The Journal of laboratory and clinical medicine, 1972, Volume: 79, Issue:3

    Topics: Analgesia; Animals; Biotransformation; Estradiol; Hexobarbital; Hydrocarbons; Kinetics; Male; Methadone; Microsomes, Liver; Morphinans; Phenobarbital; Rats; Testosterone

1972
Modifications of the XAD-2 resin column method for the extraction of drugs of abuse from human urine.
    Journal of chromatography, 1972, Sep-20, Volume: 71, Issue:3

    Topics: Amphetamine; Carbon Isotopes; Humans; Ion Exchange Resins; Methadone; Morphine; Phenobarbital; Tritium

1972
Narcotic withdrawal in the newborn.
    American family physician, 1972, Volume: 6, Issue:1

    Topics: Birth Weight; Chlorpromazine; Cocaine; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Phenobarbital; Pregnancy; Prognosis; Substance Withdrawal Syndrome; Substance-Related Disorders

1972
Observations on heroin and methadone withdrawal in the newborn.
    Pediatrics, 1971, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Apgar Score; Birth Weight; Female; Heroin; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Methadone; Neurologic Manifestations; Opium; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; Substance-Related Disorders; Vomiting

1971
The "staircase maze" and the "simple staircase" in the analysis of the psychopharmacological action of CNS depressants.
    Pharmacology, 1970, Volume: 4, Issue:3

    Topics: Analgesics; Animals; Barbiturates; Behavior, Animal; Central Nervous System; Chlorpromazine; Hydroxyzine; Hypnotics and Sedatives; Meperidine; Methadone; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Rats; Reserpine; Tranquilizing Agents

1970
New, simple method for the informative investigation of sedatives.
    Psychopharmacologia, 1967, Volume: 12, Issue:1

    Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Escape Reaction; Glutethimide; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Meprobamate; Methadone; Methods; Mice; Morphine; Nialamide; Pentobarbital; Phenobarbital; Reserpine; Tubocurarine; Urethane

1967
Relationship of plasma level and pharmacological activity of methadone.
    NIDA research monograph, 1984, Volume: 49

    Topics: Animals; Biotransformation; Brain; Dose-Response Relationship, Drug; Humans; Metabolic Clearance Rate; Methadone; Nociceptors; Opioid-Related Disorders; Phenobarbital; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1984
Case report of barbiturate-induced enhancement of methadone metabolism and withdrawal syndrome.
    The American journal of psychiatry, 1984, Volume: 141, Issue:10

    Topics: Adult; Biotransformation; Female; Heroin Dependence; Humans; Male; Methadone; Phenobarbital; Substance Withdrawal Syndrome

1984
L-alpha-acetylmethadol-induced tissue alterations in mice.
    Drug and chemical toxicology, 1984, Volume: 7, Issue:1

    Topics: Alanine Transaminase; Animals; Blood Urea Nitrogen; Glutathione; Kidney; Liver; Male; Methadone; Methadyl Acetate; Methylcholanthrene; Mice; Mice, Inbred ICR; Necrosis; Phenobarbital; Time Factors

1984
Stability of methadone pain cocktails.
    American journal of hospital pharmacy, 1982, Volume: 39, Issue:4

    Topics: Amitriptyline; Drug Combinations; Drug Stability; Hydroxyzine; Methadone; Phenobarbital

1982
Sex and age dependence of the "selective" induction of rat hepatic microsomal epoxide hydratase following trans-stilbene oxide, l-alpha-acetylmethadol, or phenobarbital treatment.
    Biochemical pharmacology, 1980, Volume: 29, Issue:24

    Topics: Age Factors; Animals; Benzopyrene Hydroxylase; Enzyme Induction; Epoxide Hydrolases; Female; Male; Methadone; Methadyl Acetate; Microsomes, Liver; Phenobarbital; Rats; Sex Factors; Stilbenes

1980
Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit.
    Intensive care medicine, 1994, Volume: 20, Issue:7

    Topics: Child; Female; Fentanyl; Humans; Iatrogenic Disease; Infant; Lorazepam; Male; Methadone; Midazolam; Phenobarbital; Substance Withdrawal Syndrome; Substance-Related Disorders

1994
[THE INHIBITION OF MORPHINE, LEVORPHAN, METHADONE AND PETHIDINE ANALGESIA IN MICE BY "SPECIFIC" AND "NONSPECIFIC" ANTAGONISTS].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1963, Nov-08, Volume: 246

    Topics: Analgesia; Animals; Atropine; Levorphanol; Meperidine; Mephenesin; Meprobamate; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain Management; Peptides; Phenobarbital; Research; Reserpine; Tissue Extracts

1963
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jan-01, Volume: 147

    Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology

1964
TREATMENT OF NARCOTIC ADDICTS IN PRIVATE PRACTICE.
    Archives of internal medicine, 1964, Volume: 114

    Topics: Chlordiazepoxide; Chlorpromazine; Drug Therapy; Family Practice; General Practice; Glucose; Hospitalization; Humans; Hyaluronoglucosaminidase; Isotonic Solutions; Meprobamate; Methadone; Motivation; Narcotics; Pentobarbital; Phenobarbital; Private Practice; Promazine; Rehabilitation; Substance-Related Disorders

1964
CONGENITAL NEONATAL NARCOTICS ADDICTION: A NATURAL HISTORY.
    American journal of public health and the nation's health, 1964, Volume: 54

    Topics: Chlorpromazine; Female; Humans; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine Dependence; Mortality; Narcotics; Opioid-Related Disorders; Opium; Phenobarbital; Pregnancy; Psychotherapy; Social Conditions; Substance-Related Disorders

1964
Management of neonatal abstinence syndrome in neonatal intensive care units: a national survey.
    Journal of perinatology : official journal of the California Perinatal Association, 2006, Jan-01, Volume: 26, Issue:1

    Topics: Humans; Hypnotics and Sedatives; Infant, Newborn; Injections, Intravenous; Intensive Care Units, Neonatal; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Psychomotor Performance; Surveys and Questionnaires; Treatment Outcome

2006
[A multidisciplinary approach is necessary in the neonatal withdrawal syndrome].
    Nederlands tijdschrift voor geneeskunde, 2006, Apr-08, Volume: 150, Issue:14

    Topics: Adult; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Male; Methadone; Narcotics; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Risk Factors; Treatment Outcome

2006
Poisoning necessitating pediatric ICU admissions: size of pupils does matter.
    Journal of the National Medical Association, 2008, Volume: 100, Issue:8

    Topics: Central Nervous System Depressants; Child; Child, Preschool; Drug Overdose; Female; Humans; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Male; Methadone; Neuromuscular Depolarizing Agents; Patient Admission; Phenobarbital; Pupil

2008
High-dose methadone in pregnant women and its effect on duration of neonatal abstinence syndrome.
    American journal of obstetrics and gynecology, 2009, Volume: 200, Issue:1

    Topics: Adult; Anticonvulsants; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Methadone; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Pregnancy Outcome; Regression Analysis; Retrospective Studies

2009
Treatment of neonatal abstinence syndrome with clonidine and chloral hydrate.
    Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:2

    Topics: Blood Pressure; Chloral Hydrate; Clonidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Retrospective Studies; Treatment Outcome

2010
Methadone toxicity and possible induction and enhanced elimination in a premature neonate.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2012, Volume: 8, Issue:4

    Topics: Cytochrome P-450 CYP3A; Drug Overdose; Humans; Infant, Newborn; Intensive Care Units; Male; Methadone; Phenobarbital; Pyrrolidines

2012
A multicenter cohort study of treatments and hospital outcomes in neonatal abstinence syndrome.
    Pediatrics, 2014, Volume: 134, Issue:2

    Topics: Adult; Clinical Protocols; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intention to Treat Analysis; Length of Stay; Male; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Phenobarbital; Treatment Outcome; Young Adult

2014
Design of pediatric oral formulations with a low proportion of methadone or phenobarbital for the treatment of neonatal abstinence syndrome.
    Pharmaceutical development and technology, 2016, Volume: 21, Issue:6

    Topics: Administration, Oral; Chemistry, Pharmaceutical; Drug Design; Drug Packaging; Drug Stability; Humans; Infant, Newborn; Methadone; Neonatal Abstinence Syndrome; Phenobarbital; Rheology; Treatment Outcome

2016
Neonatal Abstinence Syndrome: Twelve Years of Experience at a Regional Referral Center.
    Klinische Padiatrie, 2017, Volume: 229, Issue:1

    Topics: Buprenorphine; Diseases in Twins; Female; Hospitalization; Humans; Infant, Newborn; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Pregnancy; Referral and Consultation; Retrospective Studies; Substance Abuse Treatment Centers; Treatment Outcome

2017
A case of infant delirium in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:1

    Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acids; Delirium; Deprescriptions; Dexmedetomidine; Diazepam; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Methadone; Midazolam; Phenobarbital; Postoperative Complications; Pregnancy; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Risperidone

2017
Outpatient Pharmacotherapy for Neonatal Abstinence Syndrome.
    The Journal of pediatrics, 2018, Volume: 199

    Topics: Ambulatory Care; Analgesics, Opioid; Drug Therapy, Combination; Emergency Service, Hospital; Facilities and Services Utilization; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Infant, Newborn; Length of Stay; Male; Methadone; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Patient Readmission; Phenobarbital; Retrospective Studies; Treatment Outcome

2018
Stereoselective Analysis of Methadone and EDDP in Laboring Women and Neonates in Plasma and Dried Blood Spots and Association with Neonatal Abstinence Syndrome.
    American journal of perinatology, 2021, Volume: 38, Issue:9

    Topics: Analgesics, Opioid; Anticonvulsants; Dried Blood Spot Testing; Female; Humans; Infant, Newborn; Labor, Obstetric; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Pyrrolidines

2021
What Are Two Days Worth? Facing Dilemmas Together at the End of Life.
    The New England journal of medicine, 2020, Mar-05, Volume: 382, Issue:10

    Topics: Adult; Analgesics, Opioid; Cancer Pain; Humans; Hypnotics and Sedatives; Informed Consent; Male; Methadone; Palliative Care; Pelvic Neoplasms; Phenobarbital; Quality of Life; Sarcoma; Terminal Care

2020
Clonidine versus phenobarbital as adjunctive therapy for neonatal abstinence syndrome.
    Journal of perinatology : official journal of the California Perinatal Association, 2020, Volume: 40, Issue:7

    Topics: Analgesics, Opioid; Clonidine; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Prospective Studies

2020
Is Maternal Methadone Dose Associated with the Severity of Neonatal Abstinence Syndrome?
    American journal of perinatology, 2022, Volume: 39, Issue:10

    Topics: Female; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Pregnancy; Retrospective Studies

2022
Phenobarbital for alcohol withdrawal in the context of the opioid epidemic: a neglected caveat.
    Addiction (Abingdon, England), 2023, Volume: 118, Issue:7

    Topics: Alcoholism; Analgesics, Opioid; Buprenorphine; Humans; Methadone; Opiate Substitution Treatment; Opioid Epidemic; Opioid-Related Disorders; Phenobarbital; Substance Withdrawal Syndrome

2023