methadone has been researched along with pentobarbital in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (89.29) | 18.7374 |
| 1990's | 2 (3.57) | 18.2507 |
| 2000's | 1 (1.79) | 29.6817 |
| 2010's | 3 (5.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Crofford, M; Engelsher, C; Smith, AA | 2 |
| Di Gregorio, GJ; Knaiz, EK; Nagle, BT; Piraino, AJ | 1 |
| Bigelow, G; Griffiths, RR; Liebson, I | 1 |
| Burdock, GA; Kapeghian, JC; Masten, LW | 1 |
| Covault, HP; Hostetler, RM; Peterson, GR | 1 |
| Burnett, CJ; Masten, LW; Price, SR | 1 |
| Ho, IK; Mehendale, HM | 1 |
| Lefkowitz, SS; Nemeth, D | 1 |
| Altshuler, H; Phillips, P; Weaver, S | 1 |
| Berndt, WO; Ho, IK | 1 |
| Burkhalter, A; Masten, LW; Peterson, GR; Way, EL | 2 |
| Haigler, HJ | 1 |
| Alexander, GJ | 1 |
| Buchholz, J; Fraser, IM; Strother, A | 1 |
| Paule, MG; Wenger, GR | 1 |
| McMillan, DE; Rastogi, SK; Wenger, GR | 1 |
| Bowman, ER; Brase, DA; Dewey, WL; Kachur, JF; Martin, BR; Rosemond, R; Welch, S | 1 |
| Anderson, MW; Eling, TE; Fouts, JR; Orton, TC; Pickett, RD | 1 |
| Scanlon, JW | 1 |
| Stockhaus, K; Wick, H | 1 |
| Harwood, CT | 1 |
| Lamb, D; Roberts, G | 1 |
| Bowen, D; Field, F; Gutjahr, CL; Kreek, MJ; Merkatz, I; Queenan, J; Schecter, A | 1 |
| Ciofalo, FR | 1 |
| Choulis, NH | 1 |
| Bucher, UM | 1 |
| Gorodetzky, CW; Kullberg, MP | 1 |
| Grunberg, E; Klein, B; Sheehan, JE | 1 |
| Irwin, S; Kinoi, R; Van Sloten, M; Workman, MP | 1 |
| Molinengo, L; Ricci-Gamalero, S | 1 |
| Goldstein, A; Richter, JA | 1 |
| Pálosi, E; Szporny, L | 1 |
| Crowley, TJ | 1 |
| Brocco, M; McMillan, DE | 1 |
| Leander, JD | 1 |
| Leander, JD; McCleary, PE | 1 |
| Jensen, MA; Thompson, TI | 1 |
| Haertzen, CA; Ross, FE | 1 |
| Hardwick, WC; McGivney, WT; McMillan, DE | 1 |
| Miller, M; Parker, BK; Schaal, DW | 1 |
| Higley, JD; Liang, YJ; Linnoila, M; Vivian, JA; Woods, JH | 1 |
| HALL, HC | 1 |
| OSNOS, RJ | 1 |
| BERGER, H | 1 |
| HAMBURGER, E | 1 |
| COHEN, L; RICE, J | 1 |
| TAKEMORI, AE | 1 |
| WATTS, DT | 1 |
| BEECHER, HK; KEATS, AS | 1 |
| CRONHEIM, G; EHRLICH, M | 1 |
1 review(s) available for methadone and pentobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for methadone and pentobarbital
| Article | Year |
|---|---|
Human drug self-administration: double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo.
Topics: Adult; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Male; Methadone; Pentobarbital; Placebos; Self Administration; Substance-Related Disorders; Time Factors | 1979 |
54 other study(ies) available for methadone and pentobarbital
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Modulation of the respiratory depressant effect of ethanol by 5-hydroxytryptamine.
Topics: Alcohols; Animals; Carbon Dioxide; Depression, Chemical; Ethanol; Female; Fenclonine; Hydrogen-Ion Concentration; Methadone; Mice; Pentobarbital; Reserpine; Respiration; Serotonin | 1975 |
Respiratory depressant effects of ethanol: mediation by serotonin.
Topics: Alcohols; Animals; Carbon Dioxide; Chloral Hydrate; Ethanol; Female; Fenclonine; Hydrogen-Ion Concentration; Male; Methadone; Mice; Norepinephrine; Oxygen; Pentobarbital; Respiration; Serotonin | 1975 |
Secretion of drugs by the parotid glands of rats and human beings.
Topics: Acetylcholine; Adult; Amobarbital; Animals; Barbiturates; Chlorpromazine; Codeine; Glutethimide; Humans; Male; Meprobamate; Methadone; Morphine; Narcotics; Parotid Gland; Pentobarbital; Phenobarbital; Pilocarpine; Rats; Saliva; Secobarbital; Tranquilizing Agents | 1977 |
Effect of the route of administration on microsomal enzyme induction following repeated administration of methadone in the mouse.
Topics: Administration, Oral; Animals; Enzyme Induction; Injections, Subcutaneous; Male; Methadone; Mice; Mice, Inbred ICR; Microsomes, Liver; Pentobarbital; Sleep; Time Factors | 1979 |
Acute inhibition of microsomal drug metabolism by propoxyphene in narcotic tolerant/dependent mice.
Topics: Animals; Dextropropoxyphene; Drug Tolerance; Humans; Male; Methadone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Morphine Dependence; Oxidoreductases; Pentobarbital; Proadifen; Substance-Related Disorders | 1978 |
Microsomal enzyme induction following repeated oral administration of LAAM.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Body Weight; Dogs; Enzyme Induction; Male; Methadone; Methadyl Acetate; Methyltransferases; Mice; Mice, Inbred ICR; Microsomes, Liver; Organ Size; Pentobarbital; Sleep; Time Factors | 1978 |
Effects of preexposure to morphine and pentobarbital on disposition of methadone in isolated rat livers.
Topics: Animals; Bile; In Vitro Techniques; Liver; Male; Methadone; Morphine; Pentobarbital; Rats; Time Factors | 1978 |
Immunosuppression of rosette-forming cells.
Topics: Amphetamine; Animals; Body Weight; Caffeine; Erythrocytes; Humans; Immunity; Immunologic Techniques; Immunosuppression Therapy; Leukocytes; Male; Methadone; Mice; Morphine; Organ Size; Pentobarbital; Phenobarbital; Sheep; Spleen; Substance-Related Disorders | 1976 |
Intragastric self-administration of psychoactive drugs by the rhesus monkey.
Topics: Animals; Dextroamphetamine; Disease Models, Animal; Ethanol; Haplorhini; Humans; Macaca mulatta; Methadone; Pentobarbital; Psychotropic Drugs; Substance-Related Disorders; Time Factors | 1975 |
Effect of chronic administration of pentobarbital on methadone analgesia and toxicity.
Topics: Animals; Body Weight; Drug Interactions; Enzyme Induction; Liver; Male; Methadone; Mice; Microsomes, Liver; Organ Size; Oxidoreductases, N-Demethylating; Pentobarbital; Time Factors | 1976 |
Species differences in the effects of chronic, oral administration of methadone on oxidative drug metabolism.
Topics: Animals; Female; In Vitro Techniques; Liver; Male; Methadone; Mice; Mice, Inbred ICR; Mixed Function Oxygenases; Oxidoreductases; Pentobarbital; Pharmaceutical Preparations; Rats; Sleep; Species Specificity; Time Factors | 1976 |
Morphine: ability to block neuronal activity evoked by a nociceptive stimulus.
Topics: Action Potentials; Animals; Brain Stem; Chlorpromazine; Levorphanol; Male; Methadone; Morphine; Naloxone; Oxymorphone; Pain; Pentobarbital; Rats; Reticular Formation | 1976 |
Screening for drug abuse: use of NaCl to increase drug recovery from papers coated with ion-exchange resin.
Topics: Amphetamine; Chlorpromazine; Chromatography, Paper; Humans; Ion Exchange Resins; Methadone; Morphine; Morphine Derivatives; Paper; Pentobarbital; Sodium Chloride; Substance-Related Disorders | 1975 |
Effect of glucose administration on various rat hepatic constituents and on the spectral binding of hexobarbital and methadone to rat hepatic cytochrome P450.
Topics: Animals; Cholesterol; Cytochrome P-450 Enzyme System; Glucose; Hexobarbital; Lipid Metabolism; Liver; Liver Glycogen; Male; Methadone; Microsomes, Liver; Pentobarbital; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains | 1989 |
Morphine discrimination in the pigeon using a color tracking procedure.
Topics: Animals; Cocaine; Color; Columbidae; Cues; Cyclazocine; Dextroamphetamine; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Response; Male; Meperidine; Methadone; Morphine; Narcotics; Pentobarbital; Phencyclidine; Psychomotor Performance | 1986 |
Effects of optical isomers of pentobarbital on behavior in rats maintained on either the D or the L optical isomer of methadone.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Male; Methadone; Pentobarbital; Rats; Rats, Inbred Strains; Reinforcement Schedule; Stereoisomerism | 1985 |
Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits.
Topics: Animals; Biological Assay; Dextrorphan; Diazepam; Dose-Response Relationship, Drug; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Levorphanol; Male; Meperidine; Methadone; Nociceptors; Pentazocine; Pentobarbital; Proadifen; Rabbits; Time Factors | 1985 |
Xenobiotic accumulation and metabolism by isolated perfused rabbit lungs.
Topics: Amines; Amphetamine; Aniline Compounds; Animals; Carbon Isotopes; Dose-Response Relationship, Drug; Imidazoles; Imipramine; In Vitro Techniques; Lung; Male; Methadone; Organ Size; Paraquat; Pentobarbital; Perfusion; Piperazines; Rabbits; Time Factors | 1973 |
Letter: Pentazocine and neonatal withdrawal symptoms.
Topics: Female; Glutethimide; Humans; Infant, Newborn; Infant, Newborn, Diseases; Long-Term Care; Maternal-Fetal Exchange; Methadone; Pentazocine; Pentobarbital; Pregnancy; Substance Withdrawal Syndrome | 1974 |
[On the differential toxicity of drugs following subcutaneous, intragastric and intraduodenal application in rats].
Topics: Animals; Atropine; Duodenum; Epinephrine; Meperidine; Methadone; Parasympatholytics; Pentobarbital; Quaternary Ammonium Compounds; Rats; Scopolamine; Stomach; Xanthenes | 1968 |
Effect of oral administration of methadone on hepatic microsomal mixed function oxidase activity in mice.
Topics: Administration, Oral; Animals; Colorimetry; Injections, Subcutaneous; Male; Methadone; Mice; Mice, Inbred ICR; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pentobarbital; Sleep; Time Factors | 1974 |
Radioimmunoassay: its application to drugs of abuse.
Topics: Amphetamine; Animals; Antibody Formation; Antigen-Antibody Complex; Antigen-Antibody Reactions; Barbiturates; Body Fluids; Cocaine; Dronabinol; Humans; Lysergic Acid Diethylamide; Methadone; Morphine; Pentobarbital; Radioimmunoassay; Radioisotopes; Substance-Related Disorders | 1974 |
Starch and talc emboli in drug addicts' lungs.
Topics: Acetaminophen; Adult; Alcohols; Amobarbital; Animals; Barbiturates; Female; Foreign-Body Reaction; Humans; Inflammation; Injections, Intravenous; Methadone; Morphine; Pentobarbital; Pulmonary Alveoli; Pulmonary Embolism; Rats; Secobarbital; Starch; Substance-Related Disorders; Talc; Time Factors | 1972 |
Analyses of methadone and other drugs in maternal and neonatal body fluids: use in evaluation of symptoms in a neonate of mother maintained on methadone.
Topics: Adult; Amniotic Fluid; Body Fluids; Escherichia coli Infections; Female; Fetal Blood; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methadone; Milk, Human; Pentobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome | 1974 |
Effects of some narcotics and antagonists on synaptosomal 3 H-norepinephrine uptake.
Topics: Animals; Brain; Codeine; In Vitro Techniques; Methadone; Morphine; Nalorphine; Naloxone; Narcotics; Nerve Endings; Nerve Tissue Proteins; Norepinephrine; Pentobarbital; Pentylenetetrazole; Protein Binding; Rabbits; Synaptic Vesicles; Synaptosomes; Thebaine | 1972 |
Separation and quantitation of mixtures of the most commonly abused drugs.
Topics: Amobarbital; Cannabis; Chromatography, Thin Layer; Dextroamphetamine; Ephedrine; Humans; Indicators and Reagents; Lysergic Acid Diethylamide; Methadone; Methamphetamine; Methods; Morphine; Opium; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Secobarbital; Solvents; Spectrophotometry, Ultraviolet; Substance-Related Disorders | 1973 |
Respiratory changes following reflexogenic expiratory twitches.
Topics: Animals; Anthracenes; Benzoates; Codeine; Columbidae; Cough; Decerebrate State; Methadone; Nalorphine; Noscapine; Pentobarbital; Pressure; Reflex; Respiration; Time Factors | 1973 |
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders | 1974 |
Use of fluorescamine ("Fluram") to detect amphetamine in urine by thin-layer chromatography.
Topics: Amphetamine; Benzofurans; Chromatography, Ion Exchange; Chromatography, Thin Layer; Drug Stability; Evaluation Studies as Topic; Fluorescence; Glutethimide; Humans; Indicators and Reagents; Methadone; Methamphetamine; Methods; Microchemistry; Morphine; Pentobarbital; Phenobarbital; Phenothiazines; Quinine; Spiro Compounds; Substance-Related Disorders; Time Factors | 1974 |
Drug effects on distress-evoked behavior in mice: methodology and drug class comparisons.
Topics: Aggression; Animals; Arousal; Behavior, Animal; Chlordiazepoxide; Electric Stimulation; Electroshock; Ethanol; Foot; Humans; Imipramine; Locomotion; Methadone; Methamphetamine; Mice; Pentobarbital; Perphenazine; Vocalization, Animal | 1971 |
The "staircase maze" and the "simple staircase" in the analysis of the psychopharmacological action of CNS depressants.
Topics: Analgesics; Animals; Barbiturates; Behavior, Animal; Central Nervous System; Chlorpromazine; Hydroxyzine; Hypnotics and Sedatives; Meperidine; Methadone; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Rats; Reserpine; Tranquilizing Agents | 1970 |
The effects of morphine-like compounds on the light responses of the brine shrimp Artemia salina.
Topics: Animals; Decapoda; Levorphanol; Light; Methadone; Methods; Morphinans; Morphine; Nalorphine; Pentobarbital; Time Factors | 1970 |
New, simple method for the informative investigation of sedatives.
Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Escape Reaction; Glutethimide; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Meprobamate; Methadone; Methods; Mice; Morphine; Nialamide; Pentobarbital; Phenobarbital; Reserpine; Tubocurarine; Urethane | 1967 |
Substance abuse research in monkey social groups.
Topics: Animals; Humans; Macaca nemestrina; Macaca radiata; Male; Methadone; Methamphetamine; Morphine; Motor Activity; Pentobarbital; Sexual Behavior, Animal; Social Behavior; Substance-Related Disorders | 1983 |
Modification of drug effects by l-alpha-acetylmethadol.
Topics: Animals; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Male; Methadone; Methadyl Acetate; Morphine; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains | 1984 |
Attenuation of the behavioral effects of meperidine and normeperidine by daily administration of diazepam.
Topics: Animals; Columbidae; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Male; Meperidine; Methadone; Morphine; Pentobarbital | 1983 |
Opioid and nonopioid behavioral effects of methadone isomers.
Topics: Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Drug Tolerance; Fentanyl; Kinetics; Male; Methadone; Naloxone; Pentobarbital; Stereoisomerism | 1982 |
Interaction of methadone and pentobarbital on chained fixed-interval performance in pigeons.
Topics: Animals; Columbidae; Conditioning, Operant; Drug Interactions; Male; Methadone; Pentobarbital; Reinforcement Schedule | 1982 |
Strength of drug habits: for heroin, morphine, methadone, alcohol, barbiturates, pentobarbital, benzedrine, cocaine, and marijuana.
Topics: Adult; Alcoholism; Amphetamines; Barbiturates; Cannabis; Cocaine; Heroin Dependence; Humans; Male; Methadone; Morphine Dependence; Opioid-Related Disorders; Pentobarbital; Psychological Tests; Substance-Related Disorders | 1980 |
Effects of drugs on behavior in rats maintained on morphine, methadone or pentobarbital.
Topics: Animals; Behavior, Animal; Dextroamphetamine; Drug Administration Schedule; Drug Interactions; Male; Methadone; Morphine; Pentobarbital; Rats | 1980 |
Drug discrimination using a Pavlovian conditional discrimination paradigm in pigeons.
Topics: Animals; Cocaine; Columbidae; Conditioning, Classical; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Generalization, Stimulus; Methadone; Pentobarbital | 1994 |
Oral self-administration of ethanol, phencyclidine, methadone, pentobarbital and quinine in rhesus monkeys.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Central Nervous System Depressants; Ethanol; Female; Hallucinogens; Hypnotics and Sedatives; Illicit Drugs; Macaca mulatta; Male; Methadone; Narcotics; Pentobarbital; Phencyclidine; Quinine; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Reinforcement, Psychology | 1999 |
Methadone, scopolamine, and nembutal anesthesia in 15 dogs.
Topics: Anesthesia; Anesthesia, Intravenous; Animals; Barbiturates; Dogs; Methadone; Pentobarbital; Scopolamine | 1953 |
The treatment of narcotics addiction.
Topics: Humans; Methadone; Narcotics; Opioid-Related Disorders; Pentobarbital; Psychotherapy; Rehabilitation; Substance-Related Disorders | 1963 |
TREATMENT OF NARCOTIC ADDICTS IN PRIVATE PRACTICE.
Topics: Chlordiazepoxide; Chlorpromazine; Drug Therapy; Family Practice; General Practice; Glucose; Hospitalization; Humans; Hyaluronoglucosaminidase; Isotonic Solutions; Meprobamate; Methadone; Motivation; Narcotics; Pentobarbital; Phenobarbital; Private Practice; Promazine; Rehabilitation; Substance-Related Disorders | 1964 |
BARBITURATE USE IN NARCOTIC ADDICTS.
Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine Dependence; Narcotics; Opium; Pentobarbital; Seizures; Statistics as Topic; Substance-Related Disorders; Toxicology; Urea | 1964 |
NARCOTIC DRUG ADDICTION: ONE YEAR'S EXPERIECES AT PILGRIM STATE HOSPITAL.
Topics: Drug Therapy; Hepatitis; Homosexuality; Hospitals, Psychiatric; Hospitals, State; Humans; Legislation, Medical; Methadone; Narcotics; New York; Opioid-Related Disorders; Pentobarbital; Psychotherapy; Psychotherapy, Group; Residential Treatment; Substance Withdrawal Syndrome; Substance-Related Disorders; Tattooing | 1965 |
EFFECT OF CENTRAL DEPRESSANT AGENTS ON CEREBRAL GLUCOSE 6-PHOSPHATE DEHYDROGENASE ACTIVITY OF RATS.
Topics: Adrenal Glands; Brain; Chloroform; Erythrocytes; Ethanol; Glucose; Glucosephosphate Dehydrogenase; Kidney; Liver; Meperidine; Methadone; Morphine; NADP; Nalorphine; Pentobarbital; Pharmacology; Phosphates; Rats; Research; Spleen; Sulfhydryl Compounds | 1965 |
The effect of methadone isomers, morphine, and pentobarbital on the blood glucose of dogs.
Topics: Animals; Barbital; Blood Glucose; Dogs; Methadone; Morphine; Pentobarbital | 1951 |
Analgesic potency and side action liability in man of heptazone, WIN 1161-2, 6-methyl dihydromorphine, Metopon, levo-isomethadone and pentobarbital sodium, as a further effort to refine methods of evaluation of analgesic drugs.
Topics: Analgesics; Dihydromorphine; Humans; Male; Methadone; Morphinans; Pentobarbital | 1952 |
The combined use of pentobarbital sodium and methadone hydrochloride for anesthesia in dogs.
Topics: Anesthesia; Animals; Dogs; Methadone; Pentobarbital | 1950 |