methadone and paroxetine

methadone has been researched along with paroxetine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's0 (0.00)18.2507
2000's9 (69.23)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Smith, DF1
Baumann, P; Begré, S; Cosendai-Savary, L; Eap, CB; Golay, KP; Jaquet-Rochat, S; Kosel, M; Ladewig, D; von Bardeleben, U1
DeVane, CL; Wang, JS1
Berger, M; Billiard, M; Chalabreysse, M; Durst, P; Palazzolo, J; Peyrelong, JP; Vialle, A1
Bertschy, G; Bondolfi, G; Golaz, J; Rachid, F1
Haider, N; Hamid, B1

Reviews

1 review(s) available for methadone and paroxetine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for methadone and paroxetine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
The stereoselectivity of serotonin uptake in brain tissue and blood platelets: the topography of the serotonin uptake area.
    Neuroscience and biobehavioral reviews, 1986,Spring, Volume: 10, Issue:1

    Topics: Alanine; Amphetamine; Aniline Compounds; Animals; Antidepressive Agents; Blood Platelets; Brain; Fluoxetine; Humans; Male; Methadone; Mianserin; Mirtazapine; Morpholines; Naphthalenes; Nefopam; Nomifensine; Paroxetine; Piperidines; Rabbits; Serotonin; Stereoisomerism; Tranylcypromine; Viloxazine; Zimeldine

1986
Paroxetine increases steady-state concentrations of (R)-methadone in CYP2D6 extensive but not poor metabolizers.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:2

    Topics: Adult; Cytochrome P-450 CYP2D6 Inhibitors; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; Inactivation, Metabolic; Male; Metabolic Clearance Rate; Methadone; Opioid-Related Disorders; Paroxetine

2002
Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:6

    Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; In Vitro Techniques; Isoenzymes; Ketoconazole; Methadone; Microsomes, Liver; Paroxetine; Pyrrolidines; Recombinant Proteins; Stereoisomerism; Trimethoprim

2003
[Methadone and sleep apnea syndrome].
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2005, Volume: 50, Issue:3

    Topics: Adult; Brain; Clonidine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Hydroxyzine; Methadone; Methotrimeprazine; Opioid-Related Disorders; Paroxetine; Polysomnography; Sleep Apnea, Central; Sleep Stages; Substance Withdrawal Syndrome; Trimeprazine

2005
Induction of a mixed depressive episode during rTMS treatment in a patient with refractory major depression.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2006, Volume: 7, Issue:4

    Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antimanic Agents; Depressive Disorder, Major; Female; Humans; Methadone; Mood Disorders; Narcotics; Opipramol; Paroxetine; Prazepam; Psychiatric Status Rating Scales; Serotonin Syndrome; Severity of Illness Index; Substance-Related Disorders; Transcranial Magnetic Stimulation; Trazodone; Valproic Acid

2006
Spinal cord stimulator relieves neuropathic pain in a patient with radiation-induced transverse myelitis.
    Pain practice : the official journal of World Institute of Pain, 2007, Volume: 7, Issue:4

    Topics: Analgesics, Opioid; Antidepressive Agents, Second-Generation; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Electric Stimulation Therapy; Humans; Lung Neoplasms; Male; Methadone; Middle Aged; Myelitis, Transverse; Neuralgia; Paroxetine; Radiation Injuries; Spinal Cord

2007