methadone and nortriptyline

methadone has been researched along with nortriptyline in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (40.00)29.6817
2010's8 (53.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chang, TK; Ensom, MH; Kiang, TK1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ejsing, TB; Hasselstrøm, J; Linnet, K1
Flø, L; Hansen, SH; Janfelt, C; Pedersen-Bjergaard, S; Thunig, J1
Hansen, SH; Jensen, H; Li, B; Payán, MD; Pedersen-Bjergaard, S; Petersen, NJ1
Chatterton, C; Cirimele, V; Duez, M; Etter, M; Klinger, N; Turner, K1
Collina, S; Linciano, P; Listro, R; Rossi, D; Rossino, G1

Reviews

3 review(s) available for methadone and nortriptyline

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Sigma-1 receptor antagonists: promising players in fighting neuropathic pain.
    Pharmaceutical patent analyst, 2020, Volume: 9, Issue:3

    Topics: Analgesics, Opioid; Animals; Humans; Methadone; Narcotic Antagonists; Neuralgia; Nortriptyline; Patents as Topic; Receptors, sigma; Sigma-1 Receptor; Tramadol

2020

Other Studies

12 other study(ies) available for methadone and nortriptyline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
The influence of P-glycoprotein on cerebral and hepatic concentrations of nortriptyline and its metabolites.
    Drug metabolism and drug interactions, 2006, Volume: 21, Issue:3-4

    Topics: Adenosine Triphosphatases; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Cyclosporine; Drug Interactions; Enzyme Inhibitors; Liver; Male; Methadone; Mice; Mice, Knockout; Nortriptyline; Rats; Rats, Wistar; Verapamil

2006
Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine.
    Rapid communications in mass spectrometry : RCM, 2012, Jan-30, Volume: 26, Issue:2

    Topics: Diphenhydramine; Humans; Limit of Detection; Linear Models; Liquid Phase Microextraction; Meperidine; Methadone; Nortriptyline; Pharmaceutical Preparations; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2012
Nano-electromembrane extraction.
    Analytica chimica acta, 2013, Jun-27, Volume: 785

    Topics: Electricity; Electrophoresis, Capillary; Ethers; Haloperidol; Loperamide; Membranes, Artificial; Meperidine; Methadone; Nanotechnology; Nortriptyline; Sodium Chloride; Solutions; Sulfates; Water

2013
Interpretation of pharmaceutical drug concentrations in young children's head hair.
    Journal of forensic sciences, 2014, Volume: 59, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child of Impaired Parents; Child, Preschool; Chromatography, Liquid; Female; Forensic Toxicology; Hair; Humans; Infant; Methadone; Narcotics; Nortriptyline; Pyrrolidines; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol

2014