methadone has been researched along with norbuprenorphine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 10 (62.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Böttiger, Y; Bulka, A; Kouya, PF; Svensson, JO; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Conti, M; Gerra, G; Leonardi, C; Mandrioli, R; Mercolini, L; Raggi, MA | 1 |
| Lofwall, MR; Rodriguez-Rosas, ME; Siluk, D; Strain, EC; Wainer, IW | 1 |
| Fang, WB; Lin, SN; Moody, DE; Omiecinski, CJ; Strom, SC; Weyant, DM | 1 |
| Gerra, G; Marcheselli, C; Raggi, MA; Saracino, MA; Somaini, L; Zanchini, S | 1 |
| Adeniji, A; Elgadi, M; Huang, F; Joseph, D; Riesenberg, RR; Schobelock, MJ; Vince, BD; Webster, LR | 1 |
| DInh, AT; Fiellin, DA; Fiellin, LE; Lruie, BS; McCance-Katz, EF; Moody, DE; Tetrault, JM | 1 |
| Brown, S; Carmical, J; Kyle, AR; Pryor, J; Shah, D | 1 |
| Bertz, R; Bifano, M; Bruce, RD; DeMicco, M; Garimella, T; Hwang, C; Kandoussi, H; Luo, WL; Wang, R; Wastall, P | 1 |
| Barnes, AJ; Huestis, MA; Jansson, LM; Scheidweiler, KB; Swortwood, MJ | 1 |
| Liao, MZ; Mao, Q; Neradugomma, NK | 1 |
| Asatryan, A; Geoffroy, P; Kort, J; Kosloski, MP; Liu, W; Zhao, W | 1 |
| Athanasos, P; Bochner, F; Ling, W; Somogyi, AA; White, JM | 1 |
| Cavallo, DA; Donroe, JH; Holt, SR; Tetrault, JM | 1 |
| Baron, CA; Blinova, K; Johannesen, L; Patel, D; Randolph, AL; Ren, M; Sheng, J; Strauss, DG; Thiebaud, N; Tran, PN; Volpe, DA; Wu, M; Wu, WW | 1 |
1 review(s) available for methadone and norbuprenorphine
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
3 trial(s) available for methadone and norbuprenorphine
| Article | Year |
|---|---|
Simultaneous determination of buprenorphine, norbuprenorphine and the enantiomers of methadone and its metabolite (EDDP) in human plasma by liquid chromatography/mass spectrometry.
Topics: Buprenorphine; Calibration; Humans; Mass Spectrometry; Methadone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2007 |
Effect of steady-state faldaprevir on the pharmacokinetics of steady-state methadone and buprenorphine-naloxone in subjects receiving stable addiction management therapy.
Topics: Administration, Oral; Adult; Aminoisobutyric Acids; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Drug Interactions; Female; Humans; Leucine; Male; Methadone; Middle Aged; Oligopeptides; Proline; Quinolines; Substance Withdrawal Syndrome; Substance-Related Disorders; Thiazoles; Young Adult | 2015 |
No Clinically Relevant Drug-Drug Interactions between Methadone or Buprenorphine-Naloxone and Antiviral Combination Glecaprevir and Pibrentasvir.
Topics: Adult; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Cyclopropanes; Drug Interactions; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Male; Methadone; Middle Aged; Naloxone; Opiate Substitution Treatment; Opioid-Related Disorders; Proline; Protease Inhibitors; Pyrrolidines; Quinoxalines; Sulfonamides; Surveys and Questionnaires; Young Adult | 2017 |
12 other study(ies) available for methadone and norbuprenorphine
| Article | Year |
|---|---|
Comparison of the antinociceptive effect of morphine, methadone, buprenorphine and codeine in two substrains of Sprague-Dawley rats.
Topics: Analgesics; Animals; Buprenorphine; Codeine; Injections, Subcutaneous; Male; Methadone; Morphine; Morphine Derivatives; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2004 |
Simultaneous determination of methadone, buprenorphine and norbuprenorphine in biological fluids for therapeutic drug monitoring purposes.
Topics: Buprenorphine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Methadone; Reproducibility of Results; Solid Phase Extraction | 2007 |
Effect of rifampin and nelfinavir on the metabolism of methadone and buprenorphine in primary cultures of human hepatocytes.
Topics: Adult; Aged; Analgesics, Opioid; Antibiotics, Antitubercular; Biotransformation; Buprenorphine; Cells, Cultured; Chromatography, Liquid; Dealkylation; Drug Interactions; Female; Glucuronides; Hepatocytes; HIV Protease Inhibitors; Humans; Intestinal Mucosa; Kinetics; Male; Methadone; Microsomes, Liver; Middle Aged; Nelfinavir; Pyrrolidines; Rifampin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Combined liquid chromatography-coulometric detection and microextraction by packed sorbent for the plasma analysis of long acting opioids in heroin addicted patients.
Topics: Acetonitriles; Analgesics, Opioid; Buffers; Buprenorphine; Calibration; Chromatography, High Pressure Liquid; Electrochemical Techniques; Heroin Dependence; Humans; Limit of Detection; Methadone; Naloxone; Phosphates; Solid Phase Microextraction; Solvents | 2011 |
The impact of recent cocaine use on plasma levels of methadone and buprenorphine in patients with and without HIV-infection.
Topics: Adult; Anti-HIV Agents; Buprenorphine; Cocaine; Cocaine-Related Disorders; Drug Interactions; Female; HIV Infections; Humans; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Stereoisomerism; Time Factors | 2015 |
UHPLC-MS/MS quantification of buprenorphine, norbuprenorphine, methadone, and glucuronide conjugates in umbilical cord plasma.
Topics: Blood Chemical Analysis; Blood Specimen Collection; Buprenorphine; Chromatography, High Pressure Liquid; Female; Fetal Blood; Glucuronides; Humans; Infant, Newborn; Methadone; Phospholipids; Pregnancy; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry | 2015 |
Assessment of drug-drug interactions between daclatasvir and methadone or buprenorphine-naloxone.
Topics: Buprenorphine; Buprenorphine, Naloxone Drug Combination; Carbamates; Drug Interactions; Imidazoles; Methadone; Pyrrolidines; Valine | 2015 |
Simultaneous quantification of buprenorphine, naloxone and phase I and II metabolites in plasma and breastmilk by liquid chromatography-tandem mass spectrometry.
Topics: Buprenorphine; Chromatography, Liquid; Female; Glucuronides; Humans; Infant, Newborn; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Methadone; Milk, Human; Naloxone; Narcotic Antagonists; Pregnancy; Solid Phase Extraction; Tandem Mass Spectrometry | 2016 |
Buprenorphine, Norbuprenorphine, R-Methadone, and S-Methadone Upregulate BCRP/ABCG2 Expression by Activating Aryl Hydrocarbon Receptor in Human Placental Trophoblasts.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Buprenorphine; Female; Gene Knockdown Techniques; Humans; Ligands; Methadone; Placenta; Pregnancy; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; RNA, Messenger; Transcription, Genetic; Trophoblasts; Up-Regulation | 2017 |
Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Drug Tolerance; Female; Humans; Hyperalgesia; Injections, Intravenous; Male; Methadone; Morphine; Opiate Substitution Treatment; Pain Measurement; Pain Threshold; Young Adult | 2019 |
Addressing discordant quantitative urine buprenorphine and norbuprenorphine levels: Case examples in opioid use disorder.
Topics: Adult; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Cocaine-Related Disorders; Drug Contamination; Female; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Substance Abuse Detection | 2018 |
Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block.
Topics: Buprenorphine; Electrocardiography; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Ion Channel Gating; Methadone; Myocytes, Cardiac; Naloxone; Naltrexone; Potassium Channel Blockers; Receptors, Opioid; Time Factors | 2020 |