methadone and nelfinavir

methadone has been researched along with nelfinavir in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Farber, S; McCance-Katz, EF; O'Connor, A; Selwyn, PA1
Daniels, E; Hsyu, PH; Kerr, BM; Lillibridge, J1
Brown, LS; Chu, M; Kritz, S; Madray, C1
Cadafalch, J; Deig, E; Fuster, M; Marco, A; Pedrol, E; Valls, I1
Bedynek, PS; Hoffer, C; Kharasch, ED; Walker, A; Whittington, D1
Fang, WB; Lin, SN; Moody, DE; Omiecinski, CJ; Strom, SC; Weyant, DM1

Reviews

1 review(s) available for methadone and nelfinavir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for methadone and nelfinavir

ArticleYear
Pharmacokinetic interaction of nelfinavir and methadone in intravenous drug users.
    Biopharmaceutics & drug disposition, 2006, Volume: 27, Issue:2

    Topics: Administration, Oral; Adult; Drug Interactions; Female; HIV Protease Inhibitors; Humans; Male; Methadone; Middle Aged; Narcotics; Nelfinavir; Prospective Studies; Substance Abuse, Intravenous

2006

Other Studies

6 other study(ies) available for methadone and nelfinavir

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Decrease in methodone levels with nelfinavir mesylate.
    The American journal of psychiatry, 2000, Volume: 157, Issue:3

    Topics: Adult; Comorbidity; HIV Infections; HIV Protease Inhibitors; Humans; Male; Methadone; Nelfinavir; Opioid-Related Disorders

2000
Safety, efficacy, and tolerability of nelfinavir-containing antiretroviral therapy for patients coinfected with HIV and hepatitis C undergoing methadone maintenance.
    Journal of substance abuse treatment, 2006, Volume: 30, Issue:4

    Topics: Adult; Anti-HIV Agents; Female; Hepatitis C; HIV Infections; Humans; Male; Methadone; Middle Aged; Nelfinavir; Opioid-Related Disorders; Retrospective Studies

2006
[Clinical and pharmacokinetic interactions between methadone and nelfinavir (Nemesia study)].
    Medicina clinica, 2006, Jun-10, Volume: 127, Issue:2

    Topics: Adult; Drug Interactions; Female; HIV Protease Inhibitors; Humans; Male; Methadone; Narcotics; Nelfinavir; Prospective Studies

2006
Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity.
    Drug and alcohol dependence, 2009, May-01, Volume: 101, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP3A Inhibitors; HIV Protease Inhibitors; Humans; Injections, Intravenous; Metabolic Clearance Rate; Methadone; Nelfinavir; Patient Selection; Reference Values; Young Adult

2009
Effect of rifampin and nelfinavir on the metabolism of methadone and buprenorphine in primary cultures of human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:12

    Topics: Adult; Aged; Analgesics, Opioid; Antibiotics, Antitubercular; Biotransformation; Buprenorphine; Cells, Cultured; Chromatography, Liquid; Dealkylation; Drug Interactions; Female; Glucuronides; Hepatocytes; HIV Protease Inhibitors; Humans; Intestinal Mucosa; Kinetics; Male; Methadone; Microsomes, Liver; Middle Aged; Nelfinavir; Pyrrolidines; Rifampin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2009