Compounds > methadone

methadone and nalbuphine

methadone has been researched along with nalbuphine in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (12.50)	18.7374
1990's	3 (18.75)	18.2507
2000's	7 (43.75)	29.6817
2010's	3 (18.75)	24.3611
2020's	1 (6.25)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bodinier, MC; Bonnet, B; Chapelain, B; Déprez, B; Eckhoff, C; Horvath, D; Poulain, R	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bigelow, GE; Liebson, IA; Preston, KL	2
Dykstra, LA	1
Hynes, MD; Leander, JD; Reel, JK; Zimmerman, DM	1
Morgan, D; Picker, MJ	1
Sutherland, J; Walker, EA; Young, AM; Zhang, L	1
Beardsley, PM; Cook, CD	2
Moerke, MJ; Negus, SS	1
Carrasco, LP; Moreira, CM; Oliveira, RL; Silva, CP; Soares, JH; Souza, HJ	1
Alievi, MM; Boos, MZ; Gutierrez, LG; Herrera, JR; Mombach, VS; Monteiro, ER; Santos, EA	1

Reviews

1 review(s) available for methadone and nalbuphine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for methadone and nalbuphine

Article	Year
Antagonist effects of nalbuphine in opioid-dependent human volunteers. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Adult; Dose-Response Relationship, Drug; Humans; Hydromorphone; Male; Methadone; Morphinans; Nalbuphine; Naloxone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1989
The effects of lidocaine-prilocaine cream on responses to intravenous catheter placement in cats sedated with dexmedetomidine and either methadone or nalbuphine. Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:4 Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Catheterization, Peripheral; Cats; Dexmedetomidine; Female; Hypnotics and Sedatives; Lidocaine, Prilocaine Drug Combination; Methadone; Nalbuphine; Random Allocation	2019
Total intravenous anesthesia in domestic chicken (Gallus gallus domesticus) with propofol alone or in combination with methadone, nalbuphine or fentanyl for ulna osteotomy. Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:3 Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Chickens; Fentanyl; Methadone; Nalbuphine; Osteotomy; Propofol; Prospective Studies; Ulna	2020

Other Studies

12 other study(ies) available for methadone and nalbuphine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
From hit to lead. Combining two complementary methods for focused library design. Application to mu opiate ligands. Journal of medicinal chemistry, 2001, Oct-11, Volume: 44, Issue:21 Topics: Animals; Cerebral Cortex; Combinatorial Chemistry Techniques; Humans; Imidazoles; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Radioligand Assay; Rats; Receptors, Opioid, mu; Solubility; Spiro Compounds; Structure-Activity Relationship	2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Discrimination of butorphanol and nalbuphine in opioid-dependent humans. Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:3 Topics: Adult; Behavior; Blood Pressure; Body Temperature; Butorphanol; Discrimination, Psychological; Generalization, Psychological; Humans; Hydromorphone; Male; Methadone; Middle Aged; Nalbuphine; Naloxone; Psychomotor Performance; Pupil; Receptors, Opioid	1990
Butorphanol, levallorphan, nalbuphine and nalorphine as antagonists in the squirrel monkey. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Butorphanol; Dose-Response Relationship, Drug; Levallorphan; Male; Methadone; Morphinans; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri	1990
Use of beta-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Biological Assay; Buprenorphine; Butorphanol; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Etorphine; Fentanyl; Methadone; Mice; Morphine; Muscle Contraction; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, mu	1987
The mu opioid irreversible antagonist beta-funaltrexamine differentiates the discriminative stimulus effects of opioids with high and low efficacy at the mu opioid receptor. Psychopharmacology, 1998, Volume: 140, Issue:1 Topics: Animals; Buprenorphine; Butorphanol; Columbidae; Discrimination Learning; Female; Fentanyl; Levallorphan; Methadone; Morphine; Nalbuphine; Nalorphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu	1998
Discriminative stimulus effects of two doses of fentanyl in rats: pharmacological selectivity and effect of training dose on agonist and antagonist effects of mu opioids. Psychopharmacology, 2000, Volume: 148, Issue:2 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Fentanyl; Male; Methadone; Morphine; Nalbuphine; Nalorphine; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu	2000
Modulation of the discriminative stimulus effects of mu opioid agonists in rats: I. Effects of dopamine D2/3 antagonists. Behavioural pharmacology, 2004, Volume: 15, Issue:1 Topics: Animals; Benzazepines; Brain; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Heroin; Methadone; Morphine; Motivation; Nalbuphine; Naphthalenes; Piperazines; Pyrrolidines; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D3; Receptors, Opioid, mu; Salicylamides	2004
Modulation of the discriminative stimulus effects of mu opioid agonists in rats: II. Effects of dopamine D2/3 agonists. Behavioural pharmacology, 2004, Volume: 15, Issue:1 Topics: Animals; Appetitive Behavior; Brain; Discrimination Learning; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Heroin; Male; Methadone; Morphine; Motivation; Nalbuphine; Quinolines; Quinpirole; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Opioid, mu; Tetrahydronaphthalenes	2004
Role of agonist efficacy in exposure-induced enhancement of mu opioid reward in rats. Neuropharmacology, 2019, Volume: 151 Topics: Analgesics, Opioid; Animals; Buprenorphine; Dose-Response Relationship, Drug; Fentanyl; Male; Methadone; Morphine; Nalbuphine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Self Stimulation	2019