methadone and morphine

methadone has been researched along with morphine in 1197 studies

Research

Studies (1,197)

TimeframeStudies, this research(%)All Research%
pre-1990604 (50.46)18.7374
1990's123 (10.28)18.2507
2000's185 (15.46)29.6817
2010's211 (17.63)24.3611
2020's74 (6.18)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chang, TK; Ensom, MH; Kiang, TK1
Nagashima, R; Nishikawa, T; Tobita, M1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carroll, FI; Che, T; Huang, XP; Jin, J; Karpiak, J; Kroeze, WK; Lansu, K; Liu, J; McCorvy, JD; Nagase, H; Roth, BL; Shoichet, BK1
Mehta, VL1
Ahtee, L; Kääriäinen, I3
Leander, JD; McMillan, DE2
McIndewar, I; Sugrue, MF1
Davis, DC; Holtzman, SG; Shannon, HE1
Goldstein, MG; Sollod, RM1
Geller, I; Hartmann, RJ1
Oka, T; Sawa, A1
Berkowitz, BA1
Chi, CH; Dixit, BN1
Blundell, C; Slater, P1
Halpern, LM2
Dykstra, LA; McMillan, DE1
Kaistha, KK; Tadrus, R1
Segal, DS1
Browne, RG; Derrington, DC; Segal, DS1
Herndon, BL; Ringle, DA2
Geber, WF; Hung, CY; Lefkowitz, SS2
Breivik, H1
Lukoff, IF1
Almasi, J; Carlson, KR2
Yaksh, TL1
Dvorchik, BH; Hartman, RD; Stenger, VG1
Extein, I; Gold, MS; Kleber, HD; Pottash, AL; Redmond, DE1
Howd, RA; Pryor, GT1
Bergmann, F; Chaimovitz, M; Pasternak, V1
Oka, T1
Beleslin, D1
Hrdina, PD; Ling, GM; Merali, Z; Singhal, RL1
Dombrosky, JT; Thomas, JA1
Kay, DC1
Huidobro, F; Huidobro-Toro, JP; Leong Way, E1
Dewey, WL; Forbes, JE1
Creese, I; Feinberg, AP; Snyder, SH1
Donovan, MP; Shahid-Salles, KS; Thomas, JA1
Terenius, L6
Ho, TK; LaBella, FS; Pinsky, C1
Khazan, N; Meltzer, LT; Moreton, JE1
Griffith, JD; Jasinski, DR; Pevnick, JS1
Cameron, IL; Sheridan, PJ; Smith, NR1
Khazan, N; Steinfels, GF; Young, GA2
Barnett, A; Fiedler, E; Goldstein, J; Taber, R1
Gianutsos, G; Lal, H; Puri, SK1
LaBella, FS1
Richards, RK1
Dent, R; Guyda, H; Tolis, G1
Di Gregorio, GJ; Knaiz, EK; Nagle, BT; Piraino, AJ1
Ahtee, L; Carlsson, A1
Dorus, W; Renault, PF; Senay, EC1
Anderson, O; Eriksen, PB1
Castro, A; Malkus, H1
Parkhouse, RJ1
Charuvastra, VC; Ouren, J; Panell, J1
Gianutsos, G; Lal, H2
Cavanagh, K; Draisey, TF; Thibert, RJ1
Gebhart, E1
Kreek, MJ; Oratz, M; Rothschild, MA1
McKearney, JW; Smith, JB1
Chiba, S; Khazan, N; Moreton, JE; Young, GA1
Jones, BE; Prada, JA1
Downs, DA; Harrigan, SE1
Chance, WT; Krynock, GM; Rosecrans, JA1
Clouet, DH; O'Callaghan, JP; Williams, N1
Evans, DB; Liu, SJ; Wang, RI1
Sprague, GL; Takemori, AE1
Spoerlein, MT; VanderWende, C1
Holtzman, SG3
Eikenburg, DC; Stickney, JL1
Downs, DA; Wiley, JN1
Donzanti, BA; Warwick, RO1
Glennon, RA; Rosecrans, JA1
Friedler, G; Wheeling, HS1
Davis, WM; Smith, SG; Werner, TE2
Chiba, S; Khazan, N; Moreton, EJ1
Huidobro, F2
Hine, CH; Masten, LW; Way, EL1
Masten, LW1
Babbini, M; Bartoletti, M; Gaiardi, M3
Leander, JD2
Anggård, E1
Elchisak, MA; Harry, GJ; Rosecrans, JA1
Catlin, DH; Hui, KK; Li, CH; Loh, HH1
Buttery, JE; de Witt, DF; Lopez, JB1
Johnson, JH; Maughan, GT; Rosecrans, JA1
Castro, A; Mittleman, R1
Peters, MA1
Aigner, TG; Balster, RL; Ford, RD1
Eastman, M1
Sprague, GL; Takermori, AE1
Chen, RC; Ho, AK; Ho, CC1
Muir, WW; Sheehan, WC; Skarda, RT1
Ho, IK; Mehendale, HM1
Harford, RJ; Kleber, HD1
Jakubovic, A; McGeer, EG; McGeer, PL1
Sheridan, PJ1
DeAngelis, GG; McCaslin, FC; Ungerleider, JT1
Christenson, J; Cleeland, R; Davis, R; Grunberg, E; Heveran, J; Usategui-Gomez, M1
Cerceo, E; Kin, HJ1
Blachly, P; Carter, CC; Irwin, S; Marks, J1
Charuvastra, VC; Kaim, SC; Klett, CJ; Ling, W1
Lefkowitz, SS; Nemeth, D1
Baeder, H; Herndon, BL; Paull, K; Ringle, DA1
Russell-Taylor, WJ1
Kelleher, RT1
Schuster, CR1
Archer, S1
Brocco, MJ; Killam, KF; Robinson, CA1
Guerrant, GO; Hall, CT1
Stickney, JL1
Judis, J2
Rosecrans, JA; Spencer, RM1
Leander, JD; Lucot, JB1
Brindley, DN; Dodds, PF; Sanderson, RF1
Berkowitz, BA; Lee, CH1
Carney, JM; Rosecrans, JA1
Berkowitz, DS; Loew, GH; Newth, RC1
Jhamandas, K; Moffat, JA1
Bartolomé, M; Lau, C; Seidler, FJ; Slotkin, TA1
Haigler, HJ1
Gray, AP; Guardina, WJ2
Holtzman, SG; Shannon, HE1
Lunde, PK; Skjoto, J; Teisberg, P1
Henwood, RW; Mazurkiewicz-Kwilecki, I1
Austin, DL; Caddy, GR; Gottheil, E1
McNamee, HB; Meyer, RE; Mirin, SM1
Chen, RC; Ho, AK1
Anggård, E; Eriksson, JH; Holmstrand, J; Jacob, RG1
Gibson, TC1
Burkhalter, A; Masten, LW; Peterson, GR; Way, EL2
Joffe, JM; Smith, DJ1
Banford, TA; Cordova, VF1
Huang, JT; Takemori, AE1
Janda, R; Kaistha, KK; Tadrus, R1
Fultz, JM; Senay, EC1
Comaty, JE; Ehrenpreis, S; Greenberg, J1
Prianishnikova, NT; Tolstikova, GV1
Murgia, E; Walton, HF1
Reuland, DJ; Trinler, WA1
Deacon, MA; Iorio, LC; Ryan, EA1
Colpaert, FC; Janssen, PA; Lal, H; Niemegeers, CJ1
Cox, BM; Ginsburg, M; Willis, J1
Henderson, GL; Rosenkranz, RP1
Alexander, GJ2
Chan, EM; Olsen, GD; Riker, WK1
Harris, LS; Leander, JD; McMillan, DE2
McCarthy, DA; McLean, JR; Nuite, JA; Tessman, DK; Wax, J1
Nelson, PE; Selkirk, RC1
Greenstein, RA; Mintz, J; O'Brien, CP; Woody, GE1
Bell, RD; Cicero, TJ; Koch, GA; Meyer, ER1
Goldstein, A2
Craft, RM; Dykstra, LA2
Maneckjee, R; Minna, JD2
Alkadhi, KA; Hogan, YH1
Billings, B; Candido, J; Duttaroy, A; Inturrisi, CE; Lutfy, K; Sierra, V; Yoburn, BC1
Olley, JE; Pierce, TL; Tiong, GK2
Balabanova, S; Boschek, HJ; Hermann, B; Scheitler, H; Schneider, E; Wepler, R1
Bacosi, A; Caronna, A; Di Carlo, S; Pacifici, R; Pichini, S; Zuccaro, P1
Derks, J2
Chui, PT; Gin, T1
Goldberg, SR; Grayson, NA; Jaffe, JH; Johnson, RE; Katz, JL; Rice, KC; Witkin, JM1
Kapitsopoulos, G; Makhay, MM; Steigerwald, ES; Young, AM1
Desmond, DP; Esquivel, M; Maddux, JF; Vogtsberger, KN1
Bonde, J; Christrup, LL; Jonsson, T1
Ennis, M; Lorenz, W; Nehring, E; Schneider, C1
Breimer, DD; de Boer, AG; van Hoogdalem, E1
Dove, B; Göres, E; Morgenstern, E1
Negus, SS; Picker, MJ; Powell, KR1
Dykstra, LA; Oliveto, AH; Picker, MJ1
Abbrederis, K; Drexel, H; Dzien, A; Lang, AH1
Enters, EK; Guo, HZ; Ko, DJ; Pandey, U; Robinson, SE1
Balfour, HH; Gekker, G; Jackson, B; Peterson, PK; Sharp, BM1
Bochner, F; Eichelbaum, M; Mikus, G; Somogyi, AA1
Burnett, D; Richens, A; Smith, BL; Toseland, PA; Walker, G; Williams, J; Wilson, JF1
Kapitsopoulos, G; Makhay, MM; Young, AM1
Berde, CB; Beyer, JE; Bournaki, MC; Levin, CR; Sethna, NF1
Brody, MC; Chabal, C; Jacobson, L; Ward, RJ; Wasse, L1
LoPresti, D; Porreca, F; Ward, SJ1
Doty, P; Dykstra, LA; Mattox, SR; Negus, SS; Picker, MJ1
Adams, JU; Holtzman, SG; Paronis, CA1
Bailey, PL; Digre, KB; Jaeckle, KA; Jones, CR; McMahill, PC1
Cherry, DA; Cousins, MJ; Gourlay, GK; Plummer, JL1
Berde, CB; Beyer, JE; McGrath, PJ1
Frank, GB; Kokate, TG1
Foley, KM; Grabinski, PY; Inturrisi, CE; Kaiko, RF; Li, CH; Max, MB1
Foley, KM; Inturrisi, CE; Moulin, DE; Portenoy, RK; Rogers, A1
Coleman, RR; Lo, SL1
Grochow, LB; Hausheer, F; Kumor, KM1
Foley, KM; Houde, RW; Inturrisi, CE; Moulin, DE; Nip, TJ; Reidenberg, B; Wallenstein, S; Weinberg, DS1
Enterline, J; Green, L; Grochow, L; Grossman, S; Sheidler, V1
Brummitt, C; Bullock, M; Gekker, G; Hitt, J; Pentel, P; Peterson, PK; Sharp, B; Simpson, M1
Dickenson, AH; McQuay, HJ; Smallman, K; Sullivan, AF1
Koren, G; Maurice, L1
Ivarsson, M; Neil, A1
Adler, MW; Furman, MB; Geller, EB; Lynch, TJ; Martinez, RP1
Dykstra, LA; Oliveto, A; Picker, M1
Bustamante, D; Paeile, C; Pelissier, T; Saavedra, H; Tampier, L; Vergara, V1
Kaa, E; Steentoft, A; Worm, K1
Brody, MC; Chabal, C; Ireton, RC; Jacobson, L; Ward, RJ1
Deshpande, JK; Maxwell, LG; Yaster, M1
Blancquaert, JP; Lefebvre, RA; Willems, JL1
Dykstra, LA; Massie, CA; Picker, M1
Culpepper-Morgan, J; Holt, PR; Kreek, MJ; LaRoche, D; O'Bryan, L; Zhang, J1
Di Chiara, G; Imperato, A1
Carino, MA; Horita, A; Yamawaki, S1
Hyttel, J; Larsen, JJ1
Neil, A; Terenius, L1
Cotev, S; Magora, F1
Hong, O; Khazan, N; Young, G1
Jellema, JG1
Cook, CC; Lipsedge, MS1
Consolo, S; Forloni, G; Ladinsky, H; Palazzi, E1
Sica, DA; Wolfert, AI1
Hellebrekers, LJ; Mol, JA; van den Brom, WE1
Harty, GJ; Onofrio, BM; Yaksh, TL1
Boone, DJ; Caudill, SP; Hansen, HJ1
Bucarelli, A; De Montis, MG; Devoto, P; Tagliamonte, A1
Chiang, CN; Lee, CC1
Domino, EF1
Hynes, MD; Leander, JD; Reel, JK; Zimmerman, DM1
Avico, U; Belogi, L; Borelli, G; Cavallo, G; Croce, C; Santiangeli, C; Tubaro, E1
Choi, DW; Viseskul, V1
Bero, L; Field, E; Ignar, D; Kuhn, C; Lurie, S1
Clarke, KW; Paton, BS1
Contreras, E; Fernández, E; Villar, M1
Arraztoa, J; Hernández, A; Paredes, H; San Martín, S1
Dykstra, LA; Picker, M1
Inturrisi, CE; Yoburn, BC1
Mangoura, D; Sakellaridis, N; Vernadakis, A1
Frank, GB; Shetty, SS2
Cherry, DA; Cousins, MJ; Gourlay, GK1
Agren, H1
Bianchi, M; De Conno, F; Ripamonti, C; Sbanotto, A; Ventafridda, V1
Dykstra, LA; Heise, JW; Picker, M1
Rogers, AG2
Eriksson, PS; Rönnbäck, L; Rosengren, L; Wronski, A; Zeuchner, J1
Paule, MG; Wenger, GR1
Drenger, C; Evron, S; Freund, E; Rosenbaum, H1
Caine, M; Drenger, B; Evron, S; Magora, F1
Jasinski, DR; Preston, KL1
Harvey, RC; Inturrisi, CE; Madsen, J; Payne, R1
Inturrisi, CE; Payne, R1
Gourlay, GK; Lamberty, J; Willis, RJ1
Cohen, A; Inturrisi, CE; Ling, GS; Umans, JG; Yoburn, BC1
Bateman, DN; Blain, PG; Lane, RJ; Rawlins, MD1
Liu, SJ; Wang, RI2
Hovious, JR; Peters, MA2
Babbini, M; Bacchi, A; Bartoletti, M; Gaiardi, M; Gubellini, C1
Drenger, B; Evron, S; Magora, F; Samueloff, A; Simon, A1
Derendorf, H; Garrett, ER; Mattha, AG1
Parker, CW; Ryan, JJ; Williams, RC1
Gorodetzky, CW1
Baden, MM; Huang, JC1
Bastos, ML; Jukofsky, D; Mulé, SJ1
Kreuzer, H; Spiller, P1
Baettig, P; Bucher, K; Logara-Kalantzis, A1
Caldwell, J; Sever, PS1
Brister, CC; Davis, WM2
Prianishnikova, NT; Raevskii, KS2
Cadden, JJ; Feigelson, EB1
Dole, VP; Kreek, MJ; Nyswander, ME2
Elliott, HW; Hine, CH; Nomof, N; Parker, KD1
Gavitt, J; Karmin, M; Smith, AA1
Bewley, T1
Ettinger, MJ; Gero, A2
Orr, R; Scott, ME1
Röthig, J1
Fujimoto, JM; Wang, RI1
Herz, A; Hess, R; Teschemacher, H; von Cube, B1
Gero, A2
Gourley, DR1
Assouline, G1
Hayashi, G; Maruyama, Y; Smits, SE; Takemori, AE1
Kerr, FW; Pozuelo, J1
Hill, RC; Römer, D1
Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A1
Dole, VP1
Contreras, E; Huidobro, F1
Andryauskas, S; Broich, JR; Goldner, S; Hoffman, DB; Mulligan, D; Umberger, CJ1
Goldstein, A; Leute, R; Ullman, EF1
Bastiani, RJ; Phillips, RC; Schneider, RS; Ullman, EF1
Brattin, WJ; Sunshine, I1
Leute, R1
Collier, HO; Roy, AC2
Elliott, HW; Garcia, JF; Kokka, N1
Bauer, G; Konzett, H; Ziegler, E1
Boura, AL; Haddlesey, DI; Harry, EJ; Lewis, JW; Mayor, PA1
Beattie, JM; Demetriou, JA; Lowe, ML; Weissman, N1
Andryauskas, S; Broich, JR; Goldner, SJ; Hoffman, DB; Umberger, CJ1
Krstić, MK3
Bowman, WC; Buwembo, JB1
Stesin, AJ; Takemori, AE; Tulunay, FC1
Takemori, AE; Tulunay, FC1
Jones, WL; Tuason, VB1
Irey, NS1
Higgins, TN; Taylor, JD1
Harwood, CT1
Marks, MJ; Medzihradsky, F1
Geber, WF; Schramm, LC1
Goodlet, I; Sugrue, MF2
Digregorio, GJ1
Sugrue, MF1
Teiger, DG1
Edelman, I; Hiller, JM; Simon, EJ1
Dickinson, G; Jhamandas, K1
Mule, SJ1
Jamison, K; Price, S1
DuPont, RL; Katon, RN; McGinniss, MH; Sherwood, GK; Webster, JB1
Kaneto, H; Koida, M; Nakanishi, H1
Vandam, LD1
Lamb, D; Roberts, G1
McBay, AJ1
Simon, EJ1
Donald, KW; Kerr, F1
McMillan, DE1
Frings, CS1
Cushman, P; Grieco, MH1
Frings, CS; Queen, CA1
Ciofalo, FR2
Neman, RL1
Gulkus, SP; Walls, RT1
Carpenter, RW; Haertzen, CA; Jasinski, DR; Jones, BE; Kay, DC; Mansky, PA; Martin, WR1
Pert, CB; Snyder, SH1
Kubasik, NP; Sine, HE; Woytash, J1
Sohn, D1
Carmichael, FJ; Israel, Y1
Jurand, J; Knox, JH2
Colasanti, B; Khazan, N1
Choulis, NH1
Catlin, D; Cleeland, R; Grunberg, E1
Ahtee, L; Saarnivaara, L1
Donoso, E; Lipski, J; Stimmel, B1
Cushman, P1
Horng, JS; Wong, DT1
Andersen Lund, BM; Ellekjaer, EF1
Ghezzi, D; Mauron, C; Samanin, R; Valzelli, L1
Cameron, JM; Robinson, AE1
Holder, AT; Robinson, AE2
Montel, H; Starke, K1
Marks, MJ; Medzihradsky, F; Metcalfe, JI1
Fitch, FW; Hill, JH; Rothberg, RM; Wainer, BH1
Gray, AP; Robinson, DS1
Fjalland, B; Lassen, N; Nielsen, IM; Pedersen, V; Petersen, PV1
Kreek, MJ1
Gorodetzky, CW; Kullberg, MP1
Grunberg, E; Klein, B; Sheehan, JE1
Haertzen, CA; Hooks, NT; Pross, M1
Burke, DH; Mann, DE1
Horwitz, CA; Jerome, E; Paulson, C; Ross, R; Stearns, J; Ward, PC1
Froede, RC; Irey, NS1
Cimbura, G; Kofoed, J1
Ahtee, L; Boullin, DJ; Paasonen, MK; Saarnivaara, L1
Kubasik, NP; Rejent, TA; Sine, HE1
Abola, EE; Deutsch, HF; Edmundson, AB; Ely, KR; Fausch, MD; Girling, RL; Schiffer, M; Westholm, FA1
Beeler, GW; Kerr, FW; Triplett, JN1
Bowers, MB; Kleber, HD1
Baden, MM; Valanju, NN; Valanju, SN; Verma, SK1
Ho, IK; Loh, HH; Way, EL1
Baker, SL1
Buccafuri, A; Morgenstern, S; Sansur, M1
Elmowafi, AA; Gronlund, JA; Kenison, LT; Loveridge, EL1
Brown, JH; Garrett, RL1
Kumar, R; Stolerman, IP1
Hornykiewicz, O; Kuschinsky, K1
Fink, M; Freedman, AM; Zaks, A1
Arnold, PJ; Falek, A; Jordan, RB; King, BJ; Skelton, WD1
Bastos, ML; Chedekel, M; Jukofsky, D; Mulé, SJ; Saffer, E1
Alling, S; Kaplan, E; Mayron, LW1
Braun, L; Hyman, S; Oldendorf, SZ; Oldendorf, WH1
Michaux, WW; Nightingale, SL; Platt, PC1
Adler, FL; Liu, CT1
Goode, PG1
Baselt, RC; Casarett, LJ1
Heifetz, SA; McMillan, DE1
Ginsburg, M1
Geerlings, PJ; van der Helm, HJ; van der Slooten, EP1
Jhamandas, K; Phillis, JW; Pinsky, C1
Halbach, H1
Dobbs, WH1
Ladd, SL; Wallace, JE1
Ball, JC; Urbaitis, JC1
Portoghese, PS1
Marshall, AS; Weinstock, M1
Kreppel, E1
Dundee, JW; Loan, WB; Morrison, JD1
Sulman, FG; Weller, CP1
Bendick, F; Greenwald, W; Short, CE1
Molinengo, L; Ricci-Gamalero, S1
Smits, SE; Takemori, AE2
Schou, J; Worm, K1
Carchman, RA; McMillan, DE; Wolf, PS1
Goldstein, A; Richter, JA1
Antopol, W; Chryssanthou, C1
Kamei, C; Kaneto, H; Nakanishi, H; Shimomura, K1
Calise, JP; Coumbis, RJ; Fulton, CC; Rodriguez, C1
Elliott, HW1
Rethy, CR; Smith, CB; Villarreal, JE1
Bolego Zonta, N; Genovese, E; Napoli, PA; Tammiso, R1
Vallvé, C1
Tenen, SS1
Akera, T; Brody, TM1
Bauer, H; Konzett, H1
Fujimoto, FM; Inturrisi, CE1
Gunne, LM; Sandberg, CG1
Blumberg, AG; Heaton, AM1
McMartin, C; Simpson, P; Thorpe, N1
Greenhouse, DD; Irwin, S; Rendell, JK; Taber, RI1
Benzi, G; Berté, F; Crema, A; Frigo, GM1
Chernov, HI; Grumbach, L1
Parbrook, GD1
Burks, TF; Long, JP2
Blane, GF1
Contreras, E; Quijada, L; Tamayo, L1
Pálosi, E; Szporny, L1
Corti, V; Fantozzi, R; Ledda, F; Mantelli, L1
Cabib, S; Mele, A; Puglisi-Allegra, S1
Khazan, N; Young, GA1
Neil, A2
Clouet, DH; Yonehara, N1
Browne, RG; Segal, DS1
Noess, K1
Buchanan, JM; Sheridan, PJ1
Hoellinger, H; Leroux, Y; Nam, NH; Pontikis, R; Tocque, B1
Amsterdam, EA; Henderson, GL; Mason, DT; Rendig, SV1
Harris, GJ; Hasegawa, AT; Lynch, KL; Roerig, DL; Wang, RI1
Pybus, DA; Torda, TA1
Reich, SD1
Paktor, J; Vaught, JL1
Cousins, MJ; Gourlay, GK1
Kehlet, H1
Jeziorski, K; Matsumoto, H1
Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE1
Miller, RR1
Carlson, KR; Seeger, TF1
Kepes, ER; Raj, S; Thomas, P; Vemulapalli, K1
Clemens, JA; Shaar, CJ1
Ahtee, L; Attila, LM1
Fentiman, AF; Foltz, RB; Foltz, RL1
Bläsig, J; Dum, J; Herz, A1
Huidobro, F; Huidobro-Toro, JP1
Dewey, WL; Snow, AE1
Benowitz, N; Gordon, NC; Levine, J; Poole, T1
Frenk, H; Mayer, DJ; Watkins, LR1
Frenk, H; Mayer, DJ; Miller, J; Watkins, LR2
McLaughlin, PJ; Zagon, IS1
Mastropaolo, J; Moerschbaecher, JM; Thompson, DM; Winsauer, PJ1
Bigelow, GE; Liebson, IA; McCaul, ME; Stitzer, ML1
Bird, KD; Chesher, GB; Christie, MJ1
Martin, WR1
Dewey, WL1
Cervo, L; Romandini, S; Samanin, R1
Goldstein, FJ; Malseed, RT; Ossipov, MH1
Appelbaum, BD; Holtzman, SG1
Inturrisi, CE; Ling, GS; Tappe, NS1
Besser, M; Delitala, G; Grossman, A1
Bartolome, MB; Kuhn, CM1
Szeto, HH; Umans, JG1
Blandina, P; Botti, P; Caramelli, L; Fantozzi, R; Ledda, F; Mannaioni, PF; Masini, E; Moroni, F; Peruzzi, S; Zorn, AM1
Busse, LW; Fujimoto, JM; Lange, DG; Roerig, SC1
Crowley, TJ1
Bailey, M; Beeby, D; MacIntosh, KC; Welch, DB1
Allen, MC; Baldwin, D; Bullingham, RE; McQuay, HJ; Moore, RA; Symonds, HW1
Brocco, M; McMillan, DE1
Bidanset, JH; Lukash, L; Manning, TJ; Wemyss, CT; Ziminski, KR1
Jacobson, AE1
Khazan, N; Lukas, SE; Moreton, JE3
Domino, EF; Ruffing, DM1
Ogawa, GS; Sorkin, EM1
Grabinski, PY; Houde, RW; Kaiko, RF; Rogers, AG1
Carter, FE; Chau, TT; Harris, LS1
McMillan, DE; Raitano, LA1
Gaut, ZN; Nauss-Karol, C; VanderWende, C1
Jaspersen, HP; Lööf, G; Paalzow, L1
Beleslin, DB; Krstić, SK; Stefanović-Denić, K1
Breivik, H; Rennemo, F1
Joffe, JM; Soyka, LF1
Extein, I; Gold, MS; Gold, PW; Goodwin, FK; Martin, D; Pickar, D; Pottash, AL; Rebard, R; Ross, RJ; Sweeney, DR1
Sloviter, HA1
Preshaw, RL; Stutz, RM; Zenick, H1
Juskevich, JC; Lovenberg, W; O'Callaghan, JP1
Corbett, RJ; Portnow, JM1
McFarland, J; Szeto, HH; Umans, JG1
Tung, AS; Yaksh, TL1
Davis, WM; Hemnani, KL; Pace, HB1
Clouet, DH; Williams, N1
Burklund, KE; Lichtblau, L; Sparber, SB1
Khazan, N; Steinfels, GF; Wolf, DL; Young, GA1
Bigelow, GE; Liebson, I; Stitzer, ML1
Beleslin, DB; Krstić, SK; Mićić, D; Stefanović-Denić, K; Strbac, M1
Kay, DC; Neidert, GL; Pickworth, WB1
Ghosh, AK; Mukherji, B; Sakai, N; Sloviter, HA; Suemaru, K1
Hardwick, WC; McGivney, WT; McMillan, DE1
Strauss, A1
Mercadante, S4
Finnegan, MJ; Leng, G1
Di Bello, MG; Mannaioni, PF; Masini, E; Mugnai, L; Raspanti, S; Romano, V2
Martinez, RP; Raffa, RB1
Betley, K; Laur, DF; Sinkovich, J1
Christensen, CB; Christrup, LL; Kristensen, K1
Bloch-Lainé, JF; Carpentier, J; Hefez, S1
Boissonnas, A1
Jensen, NH; Jensen, TS; Sjøgren, P1
Finnegan, MJ; Leng, G; Miles, JB; Morley, JS; Watt, JW; Wells, JC1
Uchtenhagen, A1
Kaa, E; Kringsholm, B; Simonsen, KW; Steentoft, A; Worm, K1
Gori, E; Pacifici, R; Parolaro, D; Patrini, G; Venier, I; Zuccaro, P1
Coleman, GJ; Hay, M; McLachlan, CD1
Fey, P; Moeller, MR; Wennig, R1
Allsop, JR; Davidson, I; Dutton, DA; Haynes, SR1
Ekman, R; Hedner, T; Samuelsson, H1
Bacosi, A; Di Carlo, S; Pacifici, R; Zuccaro, P1
Hamunen, K1
Borgbjerg, FM; Eriksen, J; Groth Clausen, T1
Calvo, R; Garrido, MJ; Gomez, E; Jiminez, R1
Belzile, M; Bruera, E; Hanson, J; Kuehn, N; Pereira, J; Watanabe, S1
Ceder, G; Holmgren, P; Kaa, E; Kristinsson, J; Pikkarainen, J; Simonsen, KW; Steentoft, A; Teige, B; Vuori, E; Wethe, G1
Fossati, G; Gori, E; Massi, P; Mazzone, A; Mazzucchelli, I; Parolaro, D; Patrini, G; Ricevuti, G1
Fournié-Zaluski, MC; Maldonado, R; Roques, BP; Ruiz, F1
Hug, I; Knoll, B; Ladewig, D; Mohler, B; Stohler, R1
Blake, AD; Bot, G; Freeman, JC; Reisine, T1
Diamant, K; Fischer, G; Hauk, R; Kasper, S; Lenzinger, E; Pezawas, L; Schneider, C1
Clausen, TG1
Bruera, E; Fainsinger, RL1
Borsook, D; Chandler, SW; Manfredi, PL; Payne, R1
Busquets, X; Garcia-Sevilla, JA; Ventayol, P1
Fischer, G; Grünberger, J; Linzmayer, L1
Ikizler, Y; Koren, G; Selby, P; Theis, JG1
De Conno, F; Polastri, D1
Brandt, MR; Cabansag, SR; France, CP1
Blake, AD; Bot, G; Li, S; Reisine, T1
Buriani, A; Cima, L; Giusti, P; Lipartiti, M1
Glass, LR; Hoppel, CL; Ingalls, ST; Schilling, CL1
Carpentier, M1
Jasinski, DR; Vaupel, DB1
Alvarez Requejo, A; Caro-Patón, T; Carvajal, A; García del Pozo, J; Martín Arias, LH; Martín de Diego, I; Rueda, AM1
Makin, MK; Morley, JS1
Fitzgibbon, DR; Ready, BL1
Escribá, PV; García-Sevilla, JA; Mayor, F; Murga, C; Ozaita, A; Ventayol, P1
Ratcliffe, JM; Sarginson, RE; Williams, PI1
Bruera, ED; Hanson, J; Lawlor, PG; Turner, KS1
Zylicz, Z1
Bani Sacchi, T; Di Bello, MG; Fomusi Ndisang, J; Ioannides, C; Mannaioni, PF; Masini, E; Ndisang, JF; Raspanti, S1
Holtzman, SG; Kimmel, HL1
Ashford, M; Forrest, AR; Galloway, JH; Holden, M; Marsh, ID1
Chodak, GW; Worwag, E1
Chang, A; Emmel, DW; Pasternak, GW; Rossi, GC1
Cheung, P; Li, JG; Liu-Chen, LY; Raffa, RB; Tzeng, TB1
Belgrade, M; River, Y1
Beauverie, P; Bouchez, J; Touzeau, D1
De Waal, EJ; Van Der Laan, JW; Van Loveren, H1
Foley, KM; Houde, RW1
Brunelli, C; De Conno, F; Groff, L; Polastri, D; Ripamonti, C; Stavrakis, A1
Agnello, A; Barresi, L; Calderone, L; Casuccio, A; Mercadante, S; Serretta, R1
Morgan, D; Picker, MJ1
Calvo, R; Garrido, MJ; Trocóniz, IF; Valle, M1
Ashby, MA; Jackson, KA; Martin, P1
Gewolb, IH; O'Brien, J; Slavin, RE1
Jyske, P; Porras, SP; Riekkola, ML; Valkó, IE1
Haemmig, RB1
Davis, AM; Inturrisi, CE1
Gonty, N; Scholes, CF; Trotman, IF1
Aschauer, HN; Eder, H; Etzersdorfer, P; Fischer, G; Gombas, W; Jagsch, R; Schatten, C; Schmidl-Mohl, K; Weninger, M1
Gong, ZH; Liao, XP; Liu, JG; Qin, BY2
Grabus, SD; Riley, AL; Smurthwaite, ST1
Bruera, E; Gagnon, B1
Clancy, C; Corkery, J; Ghodse, H; Goldfinch, R; Oyefeso, A1
Calderone, L; Casuccio, A; Mercadante, S1
Bruera, E; Daeninck, PJ1
Aeschbach, E; Satel, SL1
Daenens, P; Tytgat, J; Ulens, C1
Cano del Pozo, MI; Carvajal, A; García del Pozo, J; Martín Arias, LH; Rueda de Castro, AM1
Sutherland, J; Walker, EA; Young, AM; Zhang, L1
Gong, ZH; Liu, JG; Qin, BY2
Lee, TS1
Ng, KF; Pang, P; Shan, J; Yang, JC1
Body, JJ; Lossignol, DA; Mancini, I1
McCaffery, M; Pasero, C1
Cañadas, F; Rice, KC; Riley, AL; Stevenson, GW; Zhang, X1
Jussila, M; Porras, SP; Riekkola, ML; Sinervo, K1
Broers, B; Giner, F; Mino, A; Perneger, TV1
Dragsholt, C; Hansen, AC; Kaa, E; Kringsholm, B; Müller, IB; Simonsen, KW; Steentoft, A; Toft, J; Worm, K1
Campbell, VC; Dewey, WL; Welch, SP1
Arcuri, E; Centulio, F; Ciocca, F; D'Angiolino, G; Ginobbi, P; Marcelli, ME; Pelagalli, L; Tirelli, W1
Berbatis, CG; Bulsara, M; Lintzeris, N; Sunderland, VB1
Casas, JR; Cherny, N; Conno, F; Hanks, GW; Hanna, M; Kalso, E; McQuay, HJ; Mercadante, S; Meynadier, J; Poulain, P; Radbruch, L; Ripamonti, C; Sawe, J; Twycross, RG; Ventafridda, V1
Garzón, J; Gómez-Serranillos, P; Sánchez-Blázquez, P1
Dabbene, M; Fulfaro, F; Mercadante, S1
Boffi, R; Casuccio, A; Fulfaro, F; Gebbia, V; Groff, L; Mercadante, S; Ripamonti, C; Villari, P1
de Wit, R; Enting, RH; Lieverse, PJ; Smitt, PA; van der Rijt, CC; Wilms, EB1
Beare, CH; Bochner, F; Doverty, M; Ling, W; Menelaou, A; Somogyi, AA; White, JM1
Dickerson, ED; Ripamonti, C1
Janowska, E; Karakiewicz, B; Kozielec, T; Pach, J; Piekoszewski, W; Stanaszek, R; Winnik, L1
Black, M; Oliver, JS; Seymour, A1
Casseday, S; Davoudzadeh, D; Huestis, MA; Preston, KL; Spanbauer, AC1
Burgess, FW1
Anand, KJ; Suresh, S1
Finn, AK; Whistler, JL1
Douglas, SD; Guo, CJ; Ho, WZ; Li, Y; Tian, S; Wang, X1
Blättler, R; Gutzwiller, F; Steffen, T; Zwahlen, M1
Kasper, SM; Radbruch, L; Sabatowski, R1
Bulka, A; Plesan, A; Wiesenfeld-Hallin, Z; Xu, XJ1
Craig, AS; Feler, CA; Jones, TF; Melton, K; Moore, WL; Schaffner, W; Simmons, BP; Smith, MD1
Ballard, JL1
Aubisson, S; Cneude, F; Gourarier, L; Lejeune, C; Piquet, M; Simmat-Durand, L1
Beauverie, P; Edel, YA; Furlan, V1
Derby, S; Fischberg, D; Kornick, C; Manfredi, PL; Moryl, N; Payne, R; Santiago-Palma, J1
Eriksen, J; Hermann, CK1
Bulka, A; Wiesenfeld-Hallin, Z; Xu, XJ1
Bianchi, M; Ripamonti, C1
Mitchell, SJ; Sartain, JB1
Alonzo, NC; Bayer, BM1
Miles, J1
Bolan, EA; Pasternak, GW; Tallarida, RJ1
Duffy, SG; Macleod, AD1
Gerada, C; Greenough, A; Johnson, K1
Baud, FJ; Borron, SW; Monier, C; Risède, P1
Anglada, T; Balust, J; Beltran, J; Blasi, A; Fuster, J; Garcia-Valdecasas, JC; Martinez-Ocon, J; Taurá, P; Tercero, J1
Lan, S; Lu, H; Wang, G; Yuan, D; Zhan, C1
Borgland, SL; Christie, MJ; Connor, M; Furness, JB; Osborne, PB1
Barrett, AC; Picker, MJ; Smith, ES1
Manfredi, PL1
Boeck, G; Fischer, G; Linzmayer, L1
Bianchi, M; Casuccio, A; Ferrera, P; Fulfaro, F; Gebbia, V; Mercadante, S; Villari, P1
Ma, HM; Ng, DK; Sham, MM; Tse, DM1
Behnsen, S; Grass, H; Käferstein, H; Kimont, HG; Staak, M1
Gill, AC; Kennedy, I; Lewis, NL; Lui, K; Oei, J; Younan, N1
Jaffe, JH; O'Keeffe, C1
Lachenmeier, DW; Madea, B; Musshoff, F1
Barrot, M; Colago, EE; Haberstock-Debic, H; Nestler, EJ; Neve, RL; Pickel, VM; Rahman, Z; Svingos, AL; von Zastrow, M; Wein, M1
Aibak, H; Beaudet, A; Cahill, CM; Collier, B; Esdaile, MJ; Kieffer, BL; Morinville, A1
Merrick, J; Ventegodt, S1
LONGO, VG; NAPOLITANO, L1
BRANDSTATTER, M1
BAIN, JA; WANG, RI1
SCHMITZ-HELFF, KG1
FRASER, HF; ISBELL, H; WIKLER, A1
DAVID, NA; PHATAK, NM1
SANTARATO, R1
BODMAN, RI1
RAYPORT, M; WIKLER, A1
MILOSEVIC, MP2
BRAENDEN, OJ; EDDY, NB; HALBACH, H1
PATON, WD1
HADICKE, M; KUNTZE, M1
JULICH, E; JULICH, H1
GUSEVA, EN1
JAGENEAU, AH; JANSSEN, PA1
LYNCH, TA; MEYERS, DB1
WAGNER, HJ; WAGNER, K1
GREEN, AF1
DESHPANDE, VR; GREWAL, RS1
BURCHARD, JM; GEHLKEN, K; SCHRAPPE, O1
COLLIER, HO; SKERRY, R; WARNER, BT1
GARCIA DE JALON, PD; LASTRA SANTOS, LA1
JACOB, J; MICHAUD, G2
ZIEHME, E1
TAKEMORI, AE2
DESMOND, MM; HILL, RM1
PARIS, J; U BOIS, R; VANDENDORP, F1
ADLER, TK; WAY, EL1
JONES, A1
JACOBSEN, FG; SCHAFII-LASCHTENESCHAI, AH; ZETLER, G1
COLLINS, RJ; MACGREGOR, DW; WEEKS, JR1
THOMPSON, WL; WALTON, RP1
WANG, RI1
MASON, RM1
KOERNER, M1
STEWART, GA; YOUNG, PA1
CHAPPEL, CI; VONSEEMANN, C1
LASAGNA, L1
LARSON, DL; PORTOGHESE, PS1
COX, BM; WEINSTOCK, M1
SHEMANO, I; WENDEL, H1
KOSTERLITZ, HW; WALLIS, DI1
ADLER, TK; VEATCH, RM; WAY, EL1
GYANG, EA; KOSTERLITZ, HW; LEES, GM1
VESSMAN, J1
PESCE, A; RUGIERO, G1
BURKHALTER, A; KUPFERBERG, HJ; WAY, EL1
ABDEL-RAHMAN, MA; ELLIOTT, HW1
COLLINS, RJ; WEEKS, JR1
ANDERSON, RC; EMMERSON, JL1
BRAEUNLICH, H1
ELLIOTT, HW; MILLER, JW1
HORAKOVA, Z; VOTAVA, Z1
KIKUCHI, T; TAKAGI, H; TAKASHIMA, T1
Hernández, A; Kramer, V; Laurido, C; Paeile, C; Pelissier, T1
Fine, PG; Gazelle, G1
Bochner, F; Mitchell, TB; Somogyi, AA; White, JM2
Bailey, CP; Couch, D; Griffiths, K; Henderson, G; Johnson, E; Kelly, E1
Blättler, R; Bürki, C; Christen, S; Gschwend, P; Gutzwiller, F; Rehm, J; Seidenberg, A; Steffen, T1
STREETEN, DH; WILLAMS, EM1
SCHADER, HE1
BENNETT, DR; HENDERSHOT, LC; HOUDE, RW; IRWIN, S; SEEVERS, MH1
VIDIC, E1
WATTS, DT2
ENGELHARDT, H; KEWITZ, H; REMMER, H1
GREEN, AF; YOUNG, PA1
EISENMAN, AJ; FRASER, HF; ISBELL, H; WIKLER, A1
WIKLER, A1
Au, JD; Callahan, RJ; Liu, C; Paul, M; Yost, CS1
Wootton, M1
Campa, T; De Conno, F; Ripamonti, C1
Beardsley, PM; Cook, CD2
Nicholson, AB2
Böttiger, Y; Bulka, A; Kouya, PF; Svensson, JO; Wiesenfeld-Hallin, Z; Xu, XJ1
Carrougher, GJ; Engrav, LH; Friedrich, JB; Gibran, NS; Heckbert, SR; Heimbach, DM; Honari, S; Klein, MB; Lezotte, DC; Round, KA; Sullivan, SR; Wiechman, SA1
Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO1
BAUMHOFF, G; SCHURMEYER, A1
SATTES, H1
ALTSCHUL, S; WIKLER, A1
BEESE, FW1
GRUBER, CM; LEE, KS1
MAIER, S1
Davies, D; Desai, S; Malherbe, S; Tsui, BC1
Ali, R; Bochner, F; Foster, DJ; Jittiwutikarn, J; Somogyi, AA; White, JM1
Arcuri, E; Arese, M; Bacchi, A; Cardelli, P; Citro, G; Mastronicola, D; Mercadante, S; Sarti, P1
Birkenfeld, L; Hellmich, M; Herkenrath, P; Langenfeld, S; Müller, C; Theisohn, M1
Hood, RJ; Lambert, EW; Pellegrini, J; Stack, KM; Stewart, DJ; Unger, DV1
Fountain, J; Reith, D; Tilyard, M1
Eugenio, KR1
Jasinski, DR; Johnson, RE; Jones, HE; Milio, L1
Rix-Trott, K1
Bhimji, K1
Jung, BF; Reidenberg, MM1
Ryle, PR1
He, L; Whistler, JL2
Ertl, M; Giacomuzzi, SM; Günther, V; Haaser, W; Kopp, M; Pilsz, W; Riemer, Y; Vigl, A1
Blackburn-Munro, G; Erichsen, HK; Hao, JX; Xu, XJ1
Antonilli, L; Badiani, A; Caprioli, D; Nencini, P; Petecchia, E1
Carrigan, KA; Dykstra, LA; Fischer, BD1
Plonk, WM1
Ebner, N; Eder, H; Fischer, G; Jagsch, R; Kraigher, D; Primorac, A1
Dykstra, LA; Hughes, CE; Pitts, RC; Sigmon, SC1
Irvine, RJ; Lewanowitsch, T; Miller, JH1
Blackwell, MT; Brown, ER; Hagadorn, JI; Lainwala, S; Weinschenk, NP1
Bermejo, AM; Fernández, P; Morales, L; Tabernero, MJ; Vázquez, C1
Donn, SM; Sarkar, S1
Ertl, M; Giacomuzzi, S; Kemmler, G; Riemer, Y1
Athanasos, P; Bochner, F; Ling, W; Smith, CS; Somogyi, AA; White, JM1
Borchgrevink, PC; Dale, O; Fredheim, OM; Kaasa, S; Klepstad, P; Landrø, NI1
Bailey, JE; Barton, PL; Dart, RC; Lezotte, D; Lowenstein, SR1
Johansen, L; Streltzer, J1
Kalso, E; Kontinen, VK; Kylänlahti, I; Lemberg, K; Viljakka, K; Yli-Kauhaluoma, J1
Linardi, RL; Natalini, CC; Polydoro, Ada S1
Beijnen, JH; Rook, EJ; Van den Brink, W; van Ree, JM; van Zanten, AP1
Golianu, B; Lin, YC1
Borchgrevink, PC; Dale, O; Fredheim, OM; Hegrenaes, L; Kaasa, S; Klepstad, P1
Allen, JW; Horais, KA; Tozier, NA; Yaksh, TL1
Dolan, KA; Gilmour, S; Shearer, J; White, B; Wodak, AD1
Baewert, A; Ebner, N; Fischer, G; Jagsch, R; Peternell, A; Rohrmeister, K; Thau, K; Winklbaur, B1
Haasen, C; van den Brink, W1
Comfort, C; Kogan, M; Moryl, N; Obbens, E1
Griffiths, C; Johnson, H; Morgan, OW; Rooney, C; Seagroatt, V1
Morden, NE; Ross-Degnan, D; Roughead, E; Simoni-Wastila, L; Soumerai, S; Sullivan, SD; Zerzan, JT; Zhang, F1
Carnicelli, P; Dixon, M; Ferreira, TH; Luna, SP; Steagall, PV; Taylor, PM1
Gibert-Rahola, J; Mico, JA; Rojas-Corrales, MO1
Borchgrevink, PC; Dale, O; Fredheim, OM; Kaasa, S; Klepstad, P1
Berry, CC; Dimsdale, JE; Moore, P1
Buechler, NL; Eisenach, JC; Kim, SA; Martin, TJ; Porreca, F1
Holtman, JR; Wala, EP1
Reid, C1
Cordonnier, L; Noble, F; Roques, BP; Sanchez, M1
Anand, KJ1
DeJardin, D; Dimsdale, JE; Norman, D; Wallace, MS1
Baldwin, D; Gallina, M; Jehanli, A; Jowett, G; Speedy, T1
Arbuckle, R; Bruera, E; Curry, EA; Hung, F; Palla, S1
Bermejo, AM; Carro, AM; Fernández, P; Lago, M; Lorenzo, RA; Tabernero, MJ1
Friedrichsdorf, SJ; Kang, TI1
Mendez, IA; Trujillo, KA1
Bues-Charbit, M; Busuttil, M; Colombini, N; Dubuc, M; Einaudi, MA; Elias, R1
Prommer, EE1
BUCHANAN, OH; TAINTER, ML1
FRANK, K; WIKLER, A1
HOUGS-OLSEN, W1
ISBELL, H; VOGEL, VH1
Manfredonia, JF1
Stewart, HC; Weinstock, M1
Ebner, N; Fischer, G; Jagsch, R; Thau, K; Winklbaur, B1
Aielli, F; Casuccio, A; Ferrera, P; Ficorella, C; Fulfaro, F; Gebbia, V; Mangione, S; Mercadante, S; Porzio, G; Riina, S; Verna, L; Villari, P1
Bailey, CP; Braksator, E; Goodchild, S; Henderson, G; Kelly, E; Marrion, NV; Rodriguez-Martin, I1
Bruno, N; Correa, M; Delgado-Vélez, M; Lizardo, L; Lugo-Chinchilla, A; Morales, I; Renaud, FL; Ríos-Olivares, E; Robles, Y; Rodríguez, JW1
Benyamin, R; Glaser, SE; Hansen, H; Manchikanti, L; Patel, S; Trescot, AM1
Chrapusta, SJ; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Szyndler, J; Taracha, E1
Bond, BS1
Kurian, O; Serane, VT1
D'Addario, C; Hansen, M; Johansson, B; Langel, U; Ming, Y; Rigler, R; Schulz, R; Terenius, L; Vukojević, V1
Baker, EM; Coats, BD; Hutchinson, MR; Jekich, BM; Judd, CM; Lewis, SS; Maier, SF; Martin, D; Poole, S; Rezvani, N; Somogyi, AA; Sprunger, DB; Watkins, LR; Wieseler, JL; Zhang, Y1
Arttamangkul, S; Low, MJ; Pintar, J; Quillinan, N; von Zastrow, M; Williams, JT1
Bertol, E; Mari, F; Politi, L1
Curry, K; Fong, D; Hines, S; Theodorou, S; Williamson, A1
Bailey, JE; Campagna, E; Dart, RC1
O'Loughlin, P1
LEIMDORFER, A3
CHRISTENSEN, EM; GROSS, EG1
CHEM, KK1
FINNEGAN, JK; HAAG, HB1
JOHNSON, HT; SHIDEMAN, FE2
EISENMEN, AJ; ISBELL, H1
DENTON, JE; STRAUS, OH1
Mathieu, N; Tuna, T1
Dubajic, G; Kastelic, A; Strbad, E1
Eisenberg, E1
Leppert, W1
Bochner, F; Hay, JL; Rounsefell, B; Semple, TJ; Somogyi, AA; White, JM1
Assis, HM; Campagnol, D; Junior, AR; Monteiro, ER; Quitzan, JG1
Deeb, TZ; Hales, TG; Sharp, D1
Aguirre-Jaime, A; Benítez-Rosario, MA; Feria, M; Pérez-Méndez, L; Salinas-Martín, A1
Hopewell, J; O'Grady, MJ; White, MJ1
Anderson, BJ; Craig, F; Michel, E; Zernikow, B1
He, L; Kim, J; McFadden, W; Ou, C; van Rijn, RM; Whistler, JL1
Casuccio, A; Ferrera, P; Intravaia, G; Mangione, S; Mercadante, S; Villari, P1
Chen, G; Du, H; Jin, H; Liu, X; Wang, S; Wei, Y; Wu, Q; Yan, Z1
Cubero, DI; del Giglio, A1
Philibin, SD; Porter, JH; Vann, RE; Varvel, SA; Walentiny, DM; Wise, LE1
Chrapusta, SJ; Lehner, M; Płaźnik, A; Skórzewska, A; Taracha, E1
Beier, SL; Corrente, JE; Maiante, AA; Pedroso, CE; Teixeira Neto, FJ1
Concheiro, M; de Castro, A; Huestis, MA; Shakleya, DM1
Brosch, R; Dunkel, D; Haring, C; Madlung-Kratzer, E; Spitzer, B1
Beer, B; Libiseller, K; Pavlic, M; Woess, C; Wurm, M1
Baud, FJ; Chevillard, L; Mégarbane, B; Risède, P1
Bastanier, C; Beske, F; Esmaeili, A; Keinhorst, AK; Schlösser, R; Schuster, T1
Gross, ER; Gross, GJ; Hsu, AK1
Rosemann, T; Seidenberg, A; Senn, O1
Civit, E; de la Torre, R; Falcón, M; Garcia-Algar, O; Joya, X; Luna, A; Pichini, S; Pujadas, M; Vall, O1
Darke, S; Duflou, J; Torok, M2
Coats, BD; Hutchinson, MR; Lewis, SS; Maier, SF; Rezvani, N; Rice, KC; Somogyi, AA; Watkins, LR; Wieseler, JL; Yin, H; Zhang, Y1
Doehring, A; Lötsch, J; Prüss, H; Veh, RW1
Kolesnikov, YA; Oksman, G; Pasternak, GW1
Chiang, YC; Ho, IK; Hung, TW; Lee, CW; Yan, JY1
Baumrucker, SJ; Morgan, V; Pollock, AB; Tegeler, ML1
Holbrook, A; Kaltenbach, K1
Bohn, LM; Raehal, KM1
Dowling, G; Nangle, M; Regan, L; Tierney, J1
Arria, AM; Coyle, MG; Fischer, G; Heil, SH; Jones, HE; Kaltenbach, K; Martin, PR; O'Grady, KE; Selby, P; Stine, SM1
Bunten, H; Liang, WJ; Osselton, MD; Pounder, D; Seneviratne, C1
Chrapusta, SJ; Ćwiek, M; Dyr, W; Kostowski, W; Płaźnik, A; Taracha, E; Turzyńska, D; Walkowiak, J; Wyszogrodzka, E1
Bernard, JP; Christophersen, AS; Mørland, JG; Oiestad, EL; Vindenes, V; Waal, H; Yttredal, B1
Cone, EJ1
Borchgrevink, P; Dale, O; Fredheim, O; Hamunen, K; Mellbye, A; Svendsen, K1
Fowler, DR; Levine, B; Li, G; Li, L; Zhang, X; Zielke, HR1
Lau, EK; Quillinan, N; Virk, M; von Zastrow, M; Williams, JT1
Chou, YC; Chuang, P; Huang, CW; Lee, TS; Liu, YL; Shen, HC; Shih, CY; Wang, BE; Wu, WH; Yen, MY1
Bair, MJ; Becker, WC; Hui, S; Krebs, EE; McCoy, K; Zerzan, J1
Christophersen, AS; Johansen, U; Oiestad, AM; Oiestad, EL1
Dale, O; Kaasa, S; Klepstad, P; Moksnes, K; Paulsen, O; Rosland, JH1
Aschauer, C; Ebner, N; Fischer, G; Jagsch, R; Metz, V; Pribasnig, A; Würzl, J1
Hansen, AC; Johansen, SS; Kringsholm, B; Linnet, K; Müller, IB; Rollmann, D; Simonsen, KW1
Kutner, JS; Linnebur, SA; O'Bryant, CL; Yamashita, TE1
Enquist, J; Ferwerda, M; Milan-Lobo, L; Whistler, JL1
Hendrickson, RG; McKeown, NJ1
Boschetti, S; Destro, M; Ottolini, L; Vicentini, L1
Dale, O; Kaasa, S; Moksnes, K; Paulsen, Ø; Rosland, JH; Spigset, O1
Chen, AC; Chen, CH; Chen, YT; Chiang, IC; Chou, SY; Fang, KC; Fang, YC; Ho, IK; Hsiao, CF; Huang, CL; Kuo, HW; Lin, KM; Lin, YF; Liu, ML; Liu, SC; Liu, YL; Su, LW; Tian, JN; Tsou, HH; Wang, SC; Wu, HY1
Abrahams, RR; Hodgson, ZG1
Andersen, JM; Klykken, C; Mørland, J1
Chen, ACh; Chen, CH; Chen, YT; Fang, CP; Ho, IK; Hsiao, CF; Hsu, YT; Huang, CL; Kuo, HW; Lin, L; Liu, CT; Liu, ML; Liu, SC; Liu, YL; Shih, YH; Su, LW; Tan, HK; Tian, JN; Tsou, HH; Wu, CS; Yang, YH; Yang, YT1
Bu, Q; Cen, X; Deng, P; Deng, Y; Duan, J; Hu, C; Hu, Z; Li, Y; Shao, X; Yan, G; Zhao, J; Zhao, Y; Zhou, J; Zhu, R1
Batlle, F; Casas, M; Castells, X; Colom Farran, J; Del Río, M; Eiroa-Orosa, FJ; Pérez de Los Cobos, J; Roncero, C; Trujols, J; Valero, S1
Häkkinen, M; Launiainen, T; Ojanperä, I; Vuori, E1
Chakrabarti, J; Cuppoletti, J; Malinowska, DH; Tewari, K1
Viswesh, VV1
Chang, YH; Chen, PS; Chen, SH; Chen, SL; Chu, CH; Hong, JS; Lee, IH; Lee, SY; Lu, RB; Tao, PL; Yang, YK; Yeh, TL1
Barbera, N; Busardò, FP; Indorato, F; Romano, G1
Allouche, S; Le Marec, T; Marie, N; Noble, F1
Arria, AM; Baewert, A; Coyle, MG; Fischer, G; Heil, SH; Jones, HE; Kaltenbach, K; Martin, PR; Selby, P; Stine, SM1
Coyle, MG; Heil, SH; Holbrook, AM; Jones, HE; Kaltenbach, K; Martin, PR; Salisbury, AL; Stine, SM1
Coyle, MG; Fischer, G; Graf-Rohrmeister, K; Jones, HE; Lester, BM; Lin, H; Salisbury, AL1
Sublett, J1
Calhoun, DA; Napolitano, A; Seng, SK; Theophilopoulos, D1
Ingram, SL; Lamberts, JT; Li, MH; Neubig, RR; Smith, CE; Traynor, JR1
Agnelotti, C; Caruselli, A; Mercadante, S; Valle, A1
Coyle, MG; Fischer, G; Heil, SH; Holbrook, AM; Jones, HE; Kaltenbach, K; Martin, PR; Stine, SM1
Chiang, YC; Ho, IK; Hung, TW1
Hajj, A; Khabbaz, L; Laplanche, JL; Peoc'h, K1
Belkaï, E; Courtin, C; Crété, D; Marie-Claire, C; Noble, F1
Kilonzo, I; Twomey, F1
Chatham, MS; Dodds Ashley, ES; Juba, KM; Svengsouk, JS1
Ashley, CC; Carlyn, C; Fontenelle, DV; Fudin, HR; Fudin, J; Hinden, DA1
Kowalski, G; Leppert, W1
Grim, K; Harrison, TE; Wilder, RT1
Derry, S; Hadley, G; Moore, RA; Wiffen, PJ1
Carlson, DR; Kopecky, EA; Nalamachu, S; Pergolizzi, JV; Raffa, RB; Taylor, R; Varanasi, RK1
Ilkiw, JE; Pypendop, BH; Shilo-Benjamini, Y2
Ashmawi, HA; Cascudo, GM; de Santana Neto, J; Guimaraes, GM; Neto, JO; Sousa, AM1
Backmund, M; Beck, T; Haasen, C; Reimer, J; Ruckes, C; Schuler, C; Verthein, U; Walcher, S1
Amato, L; Bellisario, C; Davoli, M; Ferri, M; Minozzi, S1
Bisaga, A; Hołuj, M; Popik, P1
Ashmawi, HA; de Almeida Correa, M; Machado, MD; Neto, JO; Posso, IP; Scomparim, HA1
Bonnet, U; Isbruch, K; Stratmann, U1
Bruera, E; Didwaniya, N; Gottumukkala, RS; Reddy, A1
Ahmedzai, SH; Boland, JW; Foulds, GA; Pockley, AG1
Fodor, A; Tímár, J; Zelena, D1
Daldrup, T; Lerch, O; Temme, O1
Favretto, D; Ferrara, SD; Miolo, G; Monaldi, A; Tucci, M1
Arbeláez, P; Borrull, F; Maria Marcé, R; Pocurull, E1
Chang, YS; Ho, IK; Lin, KM; Liu, SW; Liu, YL; Tsai, HJ; Tsai, YT; Wang, SC1
Cardoso, CG; da Silva, TH; de Mattos-Junior, E; Marques, DR1
Comer, SD; Fischer, G; Metz, VE; Pribasnig, A; Wuerzl, J1
Babic-Hohnjec, L; Berthel, T; Bonorden-Kleij, K; Gholami, N; Haasen, C; Hämmig, R; Höpner, D; Köhler, W; Lebentrau, K; Reimer, J; Ruckes, C; Verthein, U; Vollmert, C; Weber, B1
Crowley, M; Grow, JL; Hall, ES; Jasin, LR; Klebanoff, MA; McClead, RE; Meinzen-Derr, J; Mohan, VK; Stein, H; Walsh, MC; Wexelblatt, SL2
Bermejo, AM; Carro, AM; Fernández, AM; Fernández, P; Lorenzo, RA; Regenjo, M1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
He, XH; Li, JX; Qiu, Y; Zhang, Y1
Brown, MS; Hayes, MJ; Thornton, LM1
Beck, T; Haasen, C; Reimer, J; Verthein, U1
Abreu, M; Aguado, D; Benito, J; García-Fernández, J; Segura, IA1
Bruera, E; Buckley, JS; Buckley, NS; Salpeter, SR1
Carregaro, AB; Dória, RG; Freitas, GC; Ribeiro, MH; Xavier, NV1
Degenhardt, L; Demirkol, A; Dunlop, A; Lintzeris, N; Muhleisen, P; Murnion, B; Nielsen, S1
Beck, O; Carlsson, S; Lindkvist, I; Olsson, R1
Chung, CP; Cooper, WO; Hall, K; Murray, KT; Ray, WA; Stein, CM1
Beck, T; Falcato, L; Reimer, J; Verthein, U1
Chang, YH; Chen, KC; Chen, PS; Chen, SH; Chen, SL; Chu, CH; Hong, JS; Huang, SY; Lee, IH; Lee, SY; Lu, RB; Tzeng, NS; Wang, LJ; Wang, TY; Yang, YK1
Madsen, SL; Nikolajsen, L; Sonne, NM; Zinck, L1
El-Hage, N; Fitting, S; Hauser, KF; Knapp, PE; Paris, JJ; Rodríguez, JW; Rodriguez, M; Schier, CJ; Suzuki, M; Zou, S1
Brasch-Andersen, C; Brøsen, K; Christoffersen, DJ; Damkier, P; Thomsen, JL; Worm-Leonhard, M1
Been, F; Benaglia, L; Delémont, O; Esseiva, P; Gervasoni, JP; Lucia, S1
Bressan, TF; Coelho, K; Monteiro, BS; Monteiro, ER; Simões, CR1
Hock, K; Mullins, ME; Scott, MG1
Bateman, BT; Desai, RJ; Hernandez-Diaz, S; Huybrechts, KF; Kaltenbach, K; Kerzner, LS; Mogun, H; Patorno, E1
Chen, AC; Dai, YW; Ho, IK; Hsiao, CF; Hwang, LL; Kuo, HW; Liu, SC; Liu, SW; Liu, YL; Tsou, HH; Wang, SC; Wu, SL1
Lu, Z; Majumdar, S; Pan, YX; Pasternak, GW; Rossi, GC; Xu, J1
Burke, C; Coffin, PO; Lemos, NP; Santos, GM; Visconti, AJ1
Baeyens, JM; Cobos, EJ1
Angus, JA; Tung, KH; Wright, CE1
Bailey, C; Henderson, G; Hickman, M; Hill, R; Kelly, E; Kershaw, Y; Lingford-Hughes, A; Lyndon, A; MacLachlan, J; Roberts, J; Withey, S1
Bai, H; Ding, Y; Duan, S; Gao, M; He, N; Tang, R; Wang, J; Wang, R; Yang, Y; Ye, R1
Auckburally, A; Borges, LP; Cerejo, SA; de Carvalho, LL; de Mattos-Junior, E; Nishimura, LT; Villela, IO1
de Andrade Bicudo, N; de Assis, KT; DeRossi, R; Hermeto, LC; Jardim, PHA1
Accarie, A; Marie, N; Noble, F; Posa, L1
Ahamad, K; Nolan, S; Sutherland, C; Walton, G1
Henderson, C; Karnack, C1
Brown, MS1
Andersen, LV; Banner, J; Christoffersen, DJ; Linnet, K; Simonsen, KW1
Anand, KJ; Peltz, G1
Bell, J; Jolley, CJ; Moxham, J; Rafferty, GF; Strang, J1
Hager, SJ; Spurlock, D; Young, ME1
Brucknerová, I; Dubovický, M; Mach, M; Ujházy, E1
Cape, G; Devane, J; Friedhoff, L; Glue, P; Gray, A; Harland, S; Howes, J; Hung, CT; Hung, N; Lam, F; Lockhart, M; Tunnicliff, D; Weis, H1
Auckburally, A; Borges, LP; Carvalho, LL; Cerejo, SA; Mattos-Junior, E; Nishimura, LT1
Cai, T; Mburu, G; Wang, B; Yan, Z; Yang, L; Zhang, B1
Saadat, M; Saify, K1
Flanagan, RJ; Handley, S; Patel, MX1
Brasch-Andersen, C; Brøsen, K; Christoffersen, DJ; Damkier, P; Feddersen, S; Möller, S; Thomsen, JL1
Bendová, Z; Novotný, J; Pačesová, D1
Wise, J1
Anderson, PO1
Gauthier, O; Holopherne-Doran, D; Michaut-Castrillo, J; Raillard, M; Spreux, D; Touzot-Jourde, G1
Chung, CP; Hall, K; Murray, KT; Ray, WA; Stein, CM1
Boxho, P; Charlier, C; Denooz, R; Lemaire, E; Schmidt, C2
Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE1
Farr, A; Hagmann, M; Holzer, I; Husslein, PW; Kiss, H; Kueronya, V; Petricevic, L1
McPherson, C1
Bührer, C; Hüseman, D; Mücke, S; Nagel, M; Siedentopf, J1
Diwakarla, S; Grönbladh, A; Hallberg, M; Nyberg, F; Nylander, E; Zelleroth, S1
Bailit, JL; Gibson, KS; Kumar, D; Stark, S1
McQueen, K; Murphy-Oikonen, J1
Dönselmann Im Sande, P; Hopster, K; Kästner, S1
Boxho, P; Charlier, C; Denooz, R; Dubois, N; Lemaire, E; Schmidt, C1
Cook-Sather, SD; Farrer, LA; Gelernter, J; Hakonarson, H; Jensen, KP; Kranzler, HR; Li, J; Nunez, Y; Smith, AH1
Derry, S; Nicholson, AB; Watson, GR; Wiffen, PJ1
Kim, H; Kim, J; Kim, SY; Koo, SH; Kwon, GC; Lim, J; Park, Y1
Mactier, H1
Feng, N; Li, L; Liang, LJ; Lin, C; Wu, Z1
Chen, AC; Chu, SK; Kuo, HW; Liu, SW; Liu, YL; Shih, CL; Tsou, HH; Tsung, JH; Wang, ZH; Yang, HC1
Brodie, JD; Carrion, J; Dewey, SL; Patel, K; Santoro, GC; Veith, J; Vilchez, C1
Berkwitt, AK; Bizzarro, MJ; Esserman, DA; Grossman, MR; Osborn, RR; Shapiro, ED; Xu, Y1
Brünés, N; Højsted, J; Rindom, H1
Lee, DY; Watson, N; Whittem, T1
Ohler, KH; Pham, JT1
Folger, AT; Hall, ES; Rice, WR; Wexelblatt, SL1
Haymond, S; Heiman, H; Nagpal, G1
Chung, RH; Fang, CP; Kuo, HW; Liu, TH; Liu, YL; Shih, CL; Tsou, HH; Wang, SC; Wang, Y1
Chen, ACH; Fang, CP; Kuo, HW; Liu, CC; Liu, SC; Liu, TH; Liu, YL; Wang, SC1
MacMillan, KDL; Rendon, CP; Riblet, N; Verma, K; Volpe Holmes, A; Washer, DB1
de C Williams, AC; Donaldson, LJ; Mordecai, L; Reynolds, C1
Hackner, K; Kreye, G; Masel, EK; Nauck, F; Stich, B1
Bujalska-Zadrożny, M; de Cordé, A; Filip, M; Kleczkowska, P; Krząścik, P; Wolińska, R1
Auckburally, A; de Mattos-Junior, E; Garcia, DO; Honsho, CS; Nishimura, LT; Santilli, J; Vieira, BHB1
Athanasos, P; Bochner, F; Ling, W; Somogyi, AA; White, JM1
Schiff, DM; Silverstein, M; Wachman, EM1
Burnette, T; Chernicky, L; Towers, CV1
Alizadeh, M; Miladi-Gorji, H; Zahedi-Khorasani, M1
Bogen, D; Breeze, JL; Czynski, A; D'Apolito, K; Davis, JM; Engelhardt, B; Harvey-Wilkes, K; Hudak, M; Lester, B; Marro, P; Oliveira, EL; Shenberger, J; Terrin, N; Wachman, EM1
Alizadeh, M; Bandegi, AR; Miladi-Gorji, H; Rashidy-Pour, A; Sameni, HR; Yousefi, B; Zahedi-Khorasani, M1
Briand-Madrid, L; Carrieri, P; Debrus, M; Khatmi, N; Maradan, G; Mezaache, S; Protopopescu, C; Rojas-Castro, D; Roux, P1
Dehpour, AR; Esmaeili, J; Sahebgharani, M; Shirooie, S1
Beck, T; Berthel, T; Dey, M; Dürsteler, KM; Herdener, M; Moldovanyi, A; Nordt, C; Seifritz, E; Vogel, M; Walter, M1
Benjamin, DK; Bennett, MM; Clark, RH; Greenberg, RG; Murthy, K; Smith, PB; Tolia, VN1
Greevy, RA; Griffin, MR; Grijalva, CG; Mitchel, EF; Schaffner, W; Stein, CM; Wiese, AD1
Ammar, D; Baron, L; Chvetzoff, G; Collin, E; Delorme, C; Delorme, T; Faure, S; Filbet, M; Hubault, P; Jovenin, N; Krakowski, I; Magnet, M; Michenot, N; Minello, C; Poulain, P; Rostaing, S1
Artioli, T; Bevilacqua, J; Bloomstone, J; Graicer, G; Lambert, MF; Moro, ET; Pereira, AL1
Gregory, PJ; Hein, DJ; Risoldi Cochrane, Z; Slowiczek, L1
Beck, O; Böttcher, M; Picht, F1
Kraft, WK; Mangat, AK; Schmölzer, GM1
Ambrósio, CE; Carregaro, AB; Cordeiro, YG; Fukumasu, H; Melo, CF; Roballo, KC; Schwarzbach, SV; Xavier, PLP1
Heller, NM; Maher, DP; Walia, D1
Moerke, MJ; Negus, SS1
Belcher, AM; Billing, AS; Bonaventura, J; Bonifazi, A; Cai, NS; Casadó, V; Casadó-Anguera, V; Cole, TO; Ferré, S; Greenblatt, AD; Guitart, X; Jacobson, AE; Lam, S; Massey, E; Michaelides, M; Moreno, E; Newman, AH; Purks, J; Quiroz, C; Rea, W; Rice, KC; Volkow, ND; Wagner, M; Weintraub, E; Winkelman, JW; Wish, ED1
Del Valle Arnáez, G; Santos Suárez, J1
Fairbairn, N; Giacomuzzi, SM; Gorfinkel, L; Klimas, J; Ruckes, C; Socías, ME; Wood, E1
Futamura, A; Nakagawa, T; Suga, Y; Sugawara, H; Suzuki, S; Takase, H; Torigoe, K; Uchida, M; Uesawa, Y1
Baumgartner, MR; Gastberger, S; Herdener, M; Hulka, LM; Mutschler, J; Quednow, BB; Seifritz, E; Soyka, M1
Caffaro, MM; Fennell, TR; Mortensen, NP; Snyder, RW; Yueh, YL1
Aguirre, J; Bastian, K; Buehler, PK; Hollinger, A; Lecheler, L; Rüst, CA; Siegemund, M; Slizyte, D; Studer, W; Toft, K1
Serafini, RA; Zachariou, V1
Cooney, H; Davis, P; Hodgson, K1
Cook, CE; Fantasia, HC1
Chen, J; Davis, JM; Eisler, L; Lee, JJ; Li, G; Sun, LS1
Andersen, JM; Austdal, LPE; Fjelldal, MF; Hadera, MG; Kongstorp, M; Paulsen, RE; Šulović, A1
Ardid, D; Authier, N; Bertin, C; Brousse, G; Chenaf, C; Delorme, J; Eschalier, A; Peyrière, H; Riquelme, M1
Minear, S; Wachman, EM1
Xiao, F; Yan, K; Zhou, W1
Chang, YH; Chen, P; Chen, SH; Chen, SL; Chin Chen, K; Chu, CH; Hong, JS; Huang, SY; Kuang Yang, Y; Lee, IH; Lee, SY; Lin, SH; Lu, RB; See Chen, P; Tzeng, NS; Wang, TY1
Garra, R; Sbaraglia, F1
Afarinesh, MR; Golshan, F; Haghpanah, T; Sabzalizadeh, M; Shafiei, F; Sheibani, V; Zangiabadi, I1
MacMillan, KDL1
Degenhardt, L; Gisev, N; Hall, WD; Roxburgh, A1
Casuccio, A; David, F; Mercadante, S; Spedale, VM; Villari, P1
Ahmadi, AA; Asouri, M; Gholami, M; Nasirikenari, M; Rostamnezhad, M; Saboory, E1
Khan, L1
Bogen, DL; Czynski, AJ; Dansereau, LM; Davis, JM; Engelhardt, B; Hudak, ML; Lester, BM; Marro, P; Oliveira, EL; Shenberger, J; Wachman, EM1
Evrard, CA; Haas, DM; Haneline, LS; Jones, DR; Masters, AR; Metzger, IF; Quinney, SK; Thomas, AE1
Bobby, LE; Frazier, LM; Gawronski, KM1
Dart, RC; Green, JL; Olsen, H; Severtson, G; Wang, GS1
Bach, P; Brar, R; Dong, H; Fairbairn, N; Murphy, SM; Socias, ME; Wood, E1
McPherson, ML1
Akbari, P; Miladi-Gorji, H; Najafi, M; Rezaei, AM1
Hum, A; Tan, C; Wong, JF; Yee, CM1
Brockbals, L; Kraemer, T; Staeheli, SN; Steuer, AE1
Brusseau, C; Burnette, T; Heidel, RE1
Galeone, C; Mariani, L; Motta, G; Proto, PL; Tognoli, E; Valenza, F1
Baschirotto, C; Kuhn, S; Lehmann, K; Reimer, J; Verthein, U1
Bove, J; Carlin, K; Deodhar, P; Jennings, R; McDaniel, CE; Test, M1
Braz, FR; Mattar, LA; Módolo, NSP; Navarro E Lima, LH; Pontes, JPJ; Sousa, JAG1
Camardo, SA; Czynski, AJ; Dansereau, LM; Davis, JM; Flannery, T; Lester, BM; Oliveira, EL1
Churchill, B; Root-Bernstein, R; Turke, M1
Conboy, JC; Sly, KL; Tran, RJ1
Dehpour, AR; Esmaeili, J; Mumtaz, F; Nezamoleslami, S; Shafaroodi, H; Sheibani, M1
Crowley, M; Ford, S; Kaplan, HC; Kuhnell, P; Lannon, C; Macaluso, M; McClead, R; Provost, LP; Walsh, MC; Wexelblatt, S1
Gmeiner, G; Nicolakis, J; Reiter, C; Seltenhammer, MH1
Aduroja, O; Biggs, JM; El-Metwally, D; Gopalakrishnan, M; Wijekoon, N1
Amato, L; Bellisario, C; Davoli, M; Ferri, M; Jahanfar, S; Minozzi, S1
Andersen, CU; Andersen, FD; Simonsen, U1
Ciftcioglu, J; Eckstein, N; Haas, B; Jermar, S; Kaina, B; Weickhardt, S1
Adeniyi-Jones, S; Aghai, ZH; Boelig, RC; Carola, D; Greenspan, JS; Kraft, WK; Lafferty, M; Smith, J1
Akinbi, H; Butler, D; Emoto, C; Fukuda, T; McPhail, BT; Vinks, AA1
Tobias, JD1
Grönbladh, A; Hallberg, M; Nyberg, F; Nylander, E; Zelleroth, S1
van den Anker, J1
Aranda, F; Arriaza, N; Kirmayr, M; Madrid, E; Matta, M; Papuzinski, C; Stojanova, J1
Backmund, M; Baschirotto, C; Görne, H; Jacobsen, B; Kuhn, S; Lehmann, K; Reimer, J; Scherbaum, N; Verthein, U; Walcher, S1
Altenburger, MJ; Auwärter, V; Henkel, K; Klima, M; Neukamm, MA1
Davey, JG; Martin, J; Osborn, DA; Zankl, A1
Beck, O; Böttcher, M; Keller, T; Lierheimer, S; Monticelli, FC1
Duarte, FCN; Ferraro, LHDC; Ferreira, A; Sakata, RK1
Aguilar, L; Álvarez-Navares, A; Casado-Espada, N; Gamonal-Limcaoco, S; Grau-López, L; Lozano-López, MT; Roncero, C; Vicente-Hernández, B1
Brothers, TD; Fraser, J; MacAdam, E; Morgan, B; Webster, D1
Astronomo, R; Gornalusse, GG; Hladik, F; Hughes, SM; Kim, Y; Levy, CN; McElrath, J; Ochsenbauer, C; Pandey, U; Valdez, R; Vojtech, LN1
Eidbo, SA; Hagedorn, JD; Kaufman, DE; Kropp Lopez, AK; Mathew, V; McCall, KL; Nichols, SD; Piper, BJ1
Miladi-Gorji, H; Pourhassanali, N; Zarbakhsh, S1
Giet, O; Laurent, S; Picard, S; Seresse, L; Treillet, E1
Hajizadeh, MR; Karimabad, MN; Mahmoodi, M; Rezai, M; Torabizadeh, SA1
Achuff, BJ; Causey, JC; Checchia, PA; Ghanayem, NS; Heinle, JS; Lemming, K; Sembera, KA1
Loadsman, JA1
Ambardekar, A; Carlson, A; Iskander, I; Pham, D; Price, C; Reisch, J1
Douros, A; Farhat, I; Lim, J; Panagiotoglou, D1
Gupta, M; MacMillan, KDL; Melvin, P; Morrison, TM; Murzycki, J; O'Shea, TF; Rothstein, R; Schiff, DM; Singh, R; Van Vleet, MW; Wachman, EM1
Chiroma, MS; Hidayat Baharuldin, MT; Moklas, MAM; Suliman, NA; Taib, CNM1
Badiei, A; Ghasemi, JB; Habibi, MM; Norouzi, P1
Leeman, L; Sutter, MB; Watson, H; Weitzen, S; Yonke, N1
Ashworth, J; Bifari, F; Buchhalter, A; Fant, R; Folli, F; Gauvin, D; Henningfield, J; Inturrisi, C; Lanier, R; Manfredi, PL; Pappagallo, M; Shram, M; Traversa, S1
Christoffersen, DJ; Hermansen, SK1
Bateman, BT; Esposito, DB; Hernández-Díaz, S; Huybrechts, KF; Mogun, H; Straub, L; Werler, MM1
Andersen, CU; Andersen, FD; Arjmand, S; Hvingelby, V; Joca, S; Pinilla, E; Simonsen, U; Steffensen, SC1
Abedini, M; Amirinejad, M; Haghpanah, T; Moinaddini, F; Nematollahi-Mahani, SN; Yoosefi, F1
Noroozi, A; Rahimi-Movaghar, A1
Jones, AW1
Eisenbraun, A; Martin, E; Schaff, HV; Schroeder, D; Wittwer, ED1
Buratti, E; Cerioni, A; Cingolani, M; Cippitelli, M; Froldi, R; Mietti, G; Scendoni, R2
Arnet, I; Dürsteler, KM; Grossmann, F; Hersberger, KE; Jaiteh, C1
Besharah, J; Campbell, T; Gomes, T; Kleinman, RA; Kolla, G; Ledlie, S; Leece, P; McCormack, D; Smoke, A; Sproule, B; Tadrous, M1
Dunn, LK; Esfahani, K; Naik, BI; Tennant, W; Tsang, S1
Annett, R; Bremer, D; Czynski, A; Das, A; Eggleston, B; Greenberg, R; Laptook, A; Lee, J; Lester, B; McGowan, E; Pedroza, C; Simon, A; Smith, B; Snowden, J1
Antonijevic, M; Canals, M; Hill, R; Hosking, Y; Javitch, JA; Kruegel, AC; Lane, JR; Lemel, L; Mistry, SN; Sanchez, J1
Bastos, FI; Bianchi, LM; Carvalho, RM; da Cunha, AJLA; de Magalhães-Barbosa, MC; Prata-Barbosa, A; Rodrigues-Santos, G1
Andersen, JM; Boix, F; Khoder, A; Paulsen, RE; Rajalingam, D1
Feldman, MS; Hand, I; Kim, MH; Noble, L; Wingert, WE; Yoon, JJ1
Brassart, C; Codaccioni, X; Humbert, L; Lhermitte, M; Thibault, D; Vignau, J; Vinner, E1
Choo, RE; Huestis, MA; Jones, HE; Murphy, CM1
Choo, RE; Huestis, MA; Johnson, RE; Jones, HE; Kacinko, SL1
Keith, L; Marin, SJ; McMillin, GA; Merrell, M1
Choo, RE; Concheiro, M; Elko, A; Gray, TR; Huestis, MA; Jansson, LM; Jones, HE; Williams, E1
de Castro, A; Gray, TR; Huestis, MA; Johnson, RE; Jones, HE; Shakleya, DM2
Concheiro, M; Concheiro-Guisán, A; Cruz-Landeira, A; de Castro, A; González-Colmenero, E; Lendoiro, E; López-Rivadulla, M1
Delano, K; Gareri, J; Koren, G1
Concheiro, M; Concheiro-Guisan, A; Cruz-Landeira, A; de Castro, A; Gónzalez-Colmenero, E; Lendoiro, E; López-Rivadulla, M; Macias-Cortiña, M; Peñas-Silva, P1
Busardò, FP; Carlier, J; Di Trana, A; Huestis, MA; La Maida, N; Pichini, S; Tittarelli, R1
Danell, AS; Forbes, L; Kew, K; Kuehn, D; Mamillapalli, SS; May, L; McIntyre, K; Poppenfuse, S; Ravisankar, S; Rushing, B; Smith-Joyner, A; Strom, C1

Reviews

98 review(s) available for methadone and morphine

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Cholinergic mechanisms in narcotic analgesics.
    Neuropharmacology, 1975, Volume: 14, Issue:12

    Topics: Acetylcholine; Analgesics, Opioid; Animals; Brain Chemistry; Cats; Chlorpromazine; Choline; Meperidine; Methadone; Morphine; Nalorphine; Neurons; Neurotransmitter Agents; Parasympathetic Nervous System; Time Factors

1975
Rx: 3x/week LAAM: alternative to methadone. Clinical studies: Phase I.
    NIDA research monograph, 1976, Issue:8

    Topics: Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Tolerance; Heroin; Heroin Dependence; Humans; Kinetics; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Patient Dropouts; Substance Withdrawal Syndrome; Time Factors

1976
The relationship of pharmacokinetics to pharmacological activity: morphine, methadone and naloxone.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:3

    Topics: Absorption; Aging; Aspirin; Blood Proteins; Dose-Response Relationship, Drug; Drug Interactions; Female; Half-Life; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Methadone; Morphine; Morphine Dependence; Naloxone; Propranolol; Protein Binding; Sex Factors; Substance-Related Disorders

1976
Consequences of use. Heroin and other narcotics.
    NIDA research monograph, 1977, Volume: 16

    Topics: Adolescent; Adult; Behavior; Dose-Response Relationship, Drug; Drug Tolerance; Employment; Epidemiologic Methods; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Morphine; Patient Dropouts; Research; Role; Substance-Related Disorders; United States

1977
Effects of narcotics on the reproductive system.
    Advances in sex hormone research, 1977, Volume: 3

    Topics: Adrenal Cortex; Animals; Corticosterone; Cortisone; Cyclic AMP; Female; Follicle Stimulating Hormone; Fructose; Humans; Hypothalamo-Hypophyseal System; Liver; Luteinizing Hormone; Male; Methadone; Morphine; Myometrium; Organ Size; Pregnancy; Rats; Reproduction; Semen; Testosterone; Thyroid Gland; Thyroid Hormones

1977
Radioimmunoassays of drugs of abuse in humans: a review.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 16, Issue:2

    Topics: Amphetamines; Barbiturates; Body Fluids; Cocaine; Humans; Illicit Drugs; Lysergic Acid Diethylamide; Methadone; Methaqualone; Morphine; Nicotine; Pharmaceutical Preparations; Radioimmunoassay

1977
Narcotic analgesics and aggression.
    Modern problems of pharmacopsychiatry, 1978, Volume: 13

    Topics: Aggression; Animals; Behavior, Animal; Electroshock; Humans; Methadone; Morphine; Parasympathomimetics; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome

1978
[The problem of mutagenic side effects of psychotropic substances. 2. Narcotics and addictive drugs].
    Fortschritte der Medizin, 1979, Jan-18, Volume: 97, Issue:3

    Topics: Dose-Response Relationship, Drug; Ethanol; Female; Humans; Infant, Newborn; Lysergic Acid Diethylamide; Male; Mescaline; Methadone; Morphine; Mutation; Narcotics; Psilocybin; Substance-Related Disorders

1979
Detection of drugs of abuse by radioimmunoassay: a summary of published data and some new information.
    Clinical chemistry, 1976, Volume: 22, Issue:6

    Topics: Amphetamine; Barbiturates; Cross Reactions; Drug Stability; Glutethimide; Humans; Methadone; Methaqualone; Morphine; Narcotics; Pharmaceutical Preparations; Radioimmunoassay; Saliva; Secobarbital; Substance-Related Disorders; Time Factors; Tranquilizing Agents

1976
Pharmacology of LAAM.
    NIDA research monograph, 1976, Issue:8

    Topics: Analgesics; Animals; Behavior, Animal; Dogs; Drug Evaluation, Preclinical; Female; Haplorhini; Humans; Kinetics; Male; Methadone; Methadyl Acetate; Mice; Morphine; Nalorphine; Rabbits; Rats; Stereoisomerism; Substance-Related Disorders; Time Factors

1976
The heart in myasthenia gravis.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans; Lidocaine; Meperidine; Methadone; Morphine; Myasthenia Gravis; Myocarditis; Myocardium; Neuromuscular Junction; Phenytoin; Procaine; Quinidine; Vectorcardiography

1975
[Delayed-action opioids--limitations and advantages].
    Ugeskrift for laeger, 1990, Apr-02, Volume: 152, Issue:14

    Topics: Buprenorphine; Delayed-Action Preparations; Humans; Methadone; Morphine; Pain; Palliative Care

1990
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
    Clinical pharmacokinetics, 1991, Volume: 21, Issue:1

    Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid

1991
Opiates, human peripheral blood mononuclear cells, and HIV.
    Advances in experimental medicine and biology, 1991, Volume: 288

    Topics: Acquired Immunodeficiency Syndrome; beta-Endorphin; Cells, Cultured; Heroin; HIV-1; Humans; Interferon-gamma; Leukocytes, Mononuclear; Methadone; Morphine; Respiratory Burst; Substance Abuse, Intravenous; T-Lymphocytes; Virus Replication

1991
Pediatric uses of opioids.
    Pediatric clinics of North America, 1989, Volume: 36, Issue:5

    Topics: Child; Child, Preschool; Codeine; Drug Interactions; Fentanyl; Humans; Infant; Infant, Newborn; Meperidine; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Pediatrics; Receptors, Opioid

1989
The pharmacologic management of pain in children.
    Comprehensive therapy, 1989, Volume: 15, Issue:10

    Topics: Analgesia, Epidural; Analgesics; Child; Child, Preschool; Codeine; Fentanyl; Humans; Infant; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Pain

1989
Receptor mechanisms for nociception.
    International anesthesiology clinics, 1986,Summer, Volume: 24, Issue:2

    Topics: Analgesics, Opioid; Animals; Codeine; Drug Tolerance; Methadone; Morphine; Naloxone; Neurons, Afferent; Nociceptors; Opioid-Related Disorders; Receptors, Opioid; Spinal Cord

1986
Future trends in regional spinal opioids.
    International anesthesiology clinics, 1986,Summer, Volume: 24, Issue:2

    Topics: Analgesics, Opioid; Anesthesia, Epidural; Animals; Humans; Injections, Spinal; Kinetics; Lipids; Methadone; Morphine; Pain

1986
Clonidine treatment of the opiate withdrawal syndrome. A review of clinical trials of a theory.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327

    Topics: Adrenergic Fibers; Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; Clonidine; Dextropropoxyphene; Drug Therapy, Combination; Heroin Dependence; Humans; Locus Coeruleus; Methadone; Morphine; Naltrexone; Narcotics; Norepinephrine; Rats; Substance Withdrawal Syndrome

1986
The biochemical pharmacology of abused drugs. III. Cannabis, opiates, and synthetic narcotics.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:6

    Topics: Animals; Cannabis; Chemical Phenomena; Chemistry; Columbidae; Cricetinae; Dronabinol; Drug Tolerance; Half-Life; Humans; Memory, Short-Term; Meperidine; Methadone; Microsomes, Liver; Morphine; Narcotics; Neurotransmitter Agents; Opium; Pentazocine; Perception; Rats; Substance-Related Disorders; Synaptic Transmission; Teratogens

1974
[Analgesics. 32].
    Pharmazeutische Praxis, 1969, Volume: 5

    Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine

1969
Interactions of narcotic antagonists with receptor sites.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Acetylcholine; Animals; Atropine; Binding Sites; Brain; Chromatography; Drug Tolerance; Electric Stimulation; Haplorhini; Humans; Kinetics; Levorphanol; Methadone; Mice; Molecular Conformation; Morphine; Naloxone; Narcotic Antagonists; Rats; Receptors, Drug; Structure-Activity Relationship; Substance Withdrawal Syndrome; Time Factors

1973
Biochemistry of addiction.
    Annual review of biochemistry, 1970, Volume: 39

    Topics: Animals; Azepines; Brain; Drug Tolerance; Humans; Methadone; Morphinans; Morphine; Opium; Phenazocine; Piperidines; Receptors, Drug; Substance-Related Disorders; Synapses; Synaptic Transmission

1970
Hypothesis: Inhibition of E prostaglandin-sensitive adenyl cyclase as the mechanism of morphine analgesia.
    Prostaglandins, 1974, Sep-10, Volume: 7, Issue:5

    Topics: Adenylyl Cyclases; Animals; Aspirin; Brain; Cyclic AMP; Depression, Chemical; Fluorides; Guinea Pigs; Heroin; In Vitro Techniques; Levorphanol; Meperidine; Methadone; Mice; Morphinans; Morphine; Naloxone; Prostaglandin Antagonists; Prostaglandins; Rabbits; Rats; Receptors, Drug; Sodium; Stimulation, Chemical

1974
Drug therapy: analgetic drugs--the potent analgetics.
    The New England journal of medicine, 1972, Feb-03, Volume: 286, Issue:5

    Topics: Analgesics; Blood Circulation; Fentanyl; Humans; Intestines; Levallorphan; Meperidine; Methadone; Methotrimeprazine; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Nausea; Pain; Pentazocine; Psychopharmacology; Respiration; Substance-Related Disorders; Urinary Tract; Vomiting

1972
Toxicological findings in fatal poisonings.
    Clinical chemistry, 1973, Volume: 19, Issue:4

    Topics: 1-Propanol; Alcoholic Intoxication; Amphetamine; Carbon Monoxide Poisoning; Chloral Hydrate; Chlordiazepoxide; Dextropropoxyphene; Diazepam; Ethchlorvynol; Glutethimide; Heroin; Humans; Meprobamate; Methadone; Methanol; Morphine; Orphenadrine; Paraldehyde; Pentazocine; Phenothiazines; Phenytoin; Poisoning; Quinine; Salicylates; Toxicology; Tranquilizing Agents

1973
In search of the opiate receptor.
    The American journal of the medical sciences, 1973, Volume: 266, Issue:3

    Topics: Animals; Binding Sites; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, Affinity; Cyclopropanes; Indicators and Reagents; Intestines; Levorphanol; Methadone; Morphinans; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentanols; Rats; Receptors, Drug; Tritium

1973
Editorial: Analgesia in myocardial infarction.
    British heart journal, 1974, Volume: 36, Issue:2

    Topics: Analgesia; Analgesics; Animals; Blood Pressure; Cyclizine; Heart Arrest; Heroin; Humans; Injections, Intravenous; Methadone; Morphine; Myocardial Infarction; Nausea; Pain; Pentazocine; Pulmonary Circulation; Respiration; Shock, Cardiogenic; Spirometry; Vomiting

1974
Effects of narcotics and narcotic antagonists on operant behavior.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Columbidae; Conditioning, Operant; Cyclazocine; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug Tolerance; Humans; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Reinforcement Schedule; Substance Withdrawal Syndrome

1973
Drug screening.
    CRC critical reviews in clinical laboratory sciences, 1973, Volume: 4, Issue:4

    Topics: Amphetamine; Barbiturates; Bromides; Cocaine; Codeine; Drug Stability; Ethchlorvynol; Fluorometry; Glutethimide; Hemagglutination Inhibition Tests; Humans; Meprobamate; Methadone; Methods; Morphine; Pharmaceutical Preparations; Phenothiazines; Quinine; Salicylates

1973
Stereochemical factors and receptor interactions associated with narcotic analgesics.
    Journal of pharmaceutical sciences, 1966, Volume: 55, Issue:9

    Topics: Chemistry, Pharmaceutical; Dextropropoxyphene; Humans; Methadone; Morphine; Sensory Receptor Cells

1966
Biochemical reactions between opiate receptor binding and inhibition of neurotransmission.
    NIDA research monograph, 1984, Volume: 54

    Topics: Adenylyl Cyclases; Animals; Brain Chemistry; Calcium; Calmodulin; Etorphine; Humans; Methadone; Molecular Weight; Morphine; Narcotics; Nerve Endings; Nerve Tissue Proteins; Opioid-Related Disorders; Phosphodiesterase Inhibitors; Phosphorylation; Protein Binding; Protein Kinases; Receptors, Opioid; Synaptic Transmission

1984
[Treatment of opiate withdrawal syndromes (historical review)].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1984, Oct-22, Volume: 39, Issue:43

    Topics: Antipsychotic Agents; Clonidine; Drug Evaluation; History, 19th Century; History, 20th Century; Humans; Methadone; Methadyl Acetate; Morphine; Narcotic Antagonists; Phenothiazines; Substance Withdrawal Syndrome

1984
GC/MS assays for abused drugs in body fluids.
    NIDA research monograph, 1980, Volume: 32

    Topics: Amphetamines; Chromatography, Gas; Cocaine; Diazepam; Dronabinol; Humans; Mass Spectrometry; Mescaline; Methadone; Methaqualone; Morphine; Pharmaceutical Preparations; Phencyclidine; Substance-Related Disorders

1980
Behavioral effects of prenatal exposure to opiates.
    Monographs in neural sciences, 1983, Volume: 9

    Topics: Age Factors; Animals; Animals, Suckling; Behavior, Animal; Female; Heroin; Humans; Methadone; Mice; Morphine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Substance Withdrawal Syndrome; Weaning

1983
Male mediated drug effects on offspring.
    Progress in clinical and biological research, 1980, Volume: 36

    Topics: Animals; Birth Weight; Fathers; Female; Humans; Litter Size; Male; Methadone; Morphine; Pregnancy; Rats; Reproduction; Time Factors

1980
Current management of the neonatal abstinence syndrome: a critical analysis of the evidence.
    Biology of the neonate, 1997, Volume: 71, Issue:6

    Topics: Analgesics, Opioid; Anticonvulsants; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Clonidine; Diazepam; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Infant, Newborn; MEDLINE; Methadone; Morphine; Neonatal Abstinence Syndrome; Opium; Parasympatholytics; Phenobarbital; Sympatholytics

1997
[Treatment of pain in oncology].
    Tumori, 1997, Volume: 83, Issue:2 Suppl

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Dissociative; Diphosphonates; Fentanyl; Humans; Ketamine; Methadone; Morphine; Neoplasms; Pain; Pamidronate; Suppositories; Tramadol

1997
Opioid rotation for cancer pain: rationale and clinical aspects.
    Cancer, 1999, Nov-01, Volume: 86, Issue:9

    Topics: Analgesics, Opioid; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Narcotics; Neoplasms; Pain

1999
Opioid switch to oral methadone in cancer pain.
    Current opinion in oncology, 2000, Volume: 12, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Combined Modality Therapy; Cross-Sectional Studies; Dose-Response Relationship, Drug; Humans; Methadone; Morphine; Neoplasms; Pain; Receptors, N-Methyl-D-Aspartate

2000
[Treatment of pain in cancer with systemically administered opioids].
    Nederlands tijdschrift voor geneeskunde, 2001, May-19, Volume: 145, Issue:20

    Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Administration Schedule; Humans; Infusion Pumps; Methadone; Morphine; Neoplasms; Netherlands; Oxycodone; Pain; Palliative Care; Practice Guidelines as Topic; World Health Organization

2001
Strategies for the treatment of cancer pain in the new millennium.
    Drugs, 2001, Volume: 61, Issue:7

    Topics: Analgesics, Opioid; Cannabinoids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Methadone; Morphine; Neoplasms; Nicotine; Pain

2001
Opioid tolerance in neonates: a state-of-the-art review.
    Paediatric anaesthesia, 2001, Volume: 11, Issue:5

    Topics: Analgesics, Opioid; Child Development; Drug Tolerance; Humans; Infant, Newborn; Methadone; Morphine; Protein Kinase C; Receptors, Cyclic AMP; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome

2001
Treatment of neonatal abstinence syndrome with breast milk containing methadone.
    The Journal of perinatal & neonatal nursing, 2002, Volume: 15, Issue:4

    Topics: Breast Feeding; Drug Administration Schedule; Female; Humans; Infant, Newborn; Labor, Obstetric; Methadone; Milk, Human; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Prenatal Care

2002
The use of methadone for cancer pain.
    Hematology/oncology clinics of North America, 2002, Volume: 16, Issue:3

    Topics: Analgesics, Opioid; Attitude of Health Personnel; Biological Availability; Child; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Costs; Drug Industry; Drug Information Services; Drug Interactions; Health Knowledge, Attitudes, Practice; Humans; Information Dissemination; Metabolic Clearance Rate; Methadone; Morphine; Neoplasms; Pain; Palliative Care; Patient Selection; Treatment Outcome

2002
Opioids, immunology, and host defenses of intravenous drug abusers.
    Infectious disease clinics of North America, 2002, Volume: 16, Issue:3

    Topics: Animals; Heroin; Humans; Immunity, Cellular; Methadone; Morphine; Narcotics; Prevalence; Substance Abuse, Intravenous; United States

2002
Intrathecal therapy for chronic pain.
    Stereotactic and functional neurosurgery, 2001, Volume: 77, Issue:1-4

    Topics: Administration, Oral; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Injections, Spinal; Ketamine; Methadone; Morphine; Narcotics; Neoplasms; Pain; Patient Selection; Receptors, N-Methyl-D-Aspartate

2001
Treatment of neonatal abstinence syndrome.
    Archives of disease in childhood. Fetal and neonatal edition, 2003, Volume: 88, Issue:1

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; Heroin; Humans; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Seizures; Sucking Behavior

2003
From morphine clinics to buprenorphine: regulating opioid agonist treatment of addiction in the United States.
    Drug and alcohol dependence, 2003, May-21, Volume: 70, Issue:2 Suppl

    Topics: Analgesics, Opioid; Behavior, Addictive; Buprenorphine; Humans; Methadone; Morphine; Opioid-Related Disorders; Substance Abuse Treatment Centers; United States; United States Food and Drug Administration

2003
ANTITUSSIVE DRUGS.
    Progress in medicinal chemistry, 1963, Volume: 19

    Topics: Antipsychotic Agents; Antitussive Agents; Chemistry, Pharmaceutical; Codeine; Cough; Dextromoramide; Drug Therapy; Humans; Meperidine; Methadone; Morphine; Pharmacology; Phenothiazines; Phenylacetates; Piperazines; Piperidines; Research; Thiophenes

1963
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS.
    Pharmacological reviews, 1964, Volume: 16

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Meperidine; Methadone; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Oxymorphone; Pentazocine; Phenazocine; Substance-Related Disorders; Toxicology

1964
Morphine is not the only analgesic in palliative care: literature review.
    Journal of advanced nursing, 2004, Volume: 45, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Ketamine; Methadone; Morphine; Neoplasms; Pain; Palliative Care

2004
Methadone for cancer pain.
    The Cochrane database of systematic reviews, 2004, Issue:2

    Topics: Analgesics, Opioid; Humans; Methadone; Morphine; Neoplasms; Pain; Pain Measurement; Randomized Controlled Trials as Topic

2004
Interpretation of opioid levels: comparison of levels during chronic pain therapy to levels from forensic autopsies.
    Clinical pharmacology and therapeutics, 2005, Volume: 77, Issue:4

    Topics: Analgesics, Opioid; Autopsy; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Pain, Intractable

2005
Justification for routine screening of pharmaceutical products in immune function tests: a review of the recommendations of Putman et al. (2003).
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Buprenorphine; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Guidelines as Topic; Humans; Immune System Diseases; Immunity; Methadone; Morphine; Narcotics; Salmeterol Xinafoate

2005
Innovations in agonist maintenance treatment of opioid-dependent patients.
    Current opinion in psychiatry, 2006, Volume: 19, Issue:6

    Topics: Buprenorphine; Controlled Clinical Trials as Topic; Delayed-Action Preparations; Heroin; Humans; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Quality of Life

2006
Pharmacological approaches to the management of pain in the neonatal intensive care unit.
    Journal of perinatology : official journal of the California Perinatal Association, 2007, Volume: 27 Suppl 1

    Topics: Analgesics; Analgesics, Opioid; Female; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Ketamine; Male; Methadone; Morphine; Pain; Pain Management; Treatment Outcome

2007
The management of pain in children with life-limiting illnesses.
    Pediatric clinics of North America, 2007, Volume: 54, Issue:5

    Topics: Analgesics, Opioid; Child; Chronic Disease; Codeine; Fentanyl; Humans; Hydromorphone; Ketamine; Methadone; Morphine; Nociceptors; Oxycodone; Pain; Pain Measurement; Severity of Illness Index

2007
Methadone for cancer pain.
    The Cochrane database of systematic reviews, 2007, Oct-17, Issue:4

    Topics: Analgesics, Opioid; Humans; Methadone; Morphine; Neoplasms; Pain; Pain Measurement; Randomized Controlled Trials as Topic

2007
Effectiveness of opioids in the treatment of chronic non-cancer pain.
    Pain physician, 2008, Volume: 11, Issue:2 Suppl

    Topics: Analgesics, Opioid; Drug Administration Schedule; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Oxymorphone; Pain; Quality of Life; Time Factors; Tramadol

2008
Equianalgesia: applying evidence-based practice guidelines.
    Clinical journal of oncology nursing, 2008, Volume: 12, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Codeine; Drug Monitoring; Evidence-Based Medicine; Humans; Hydromorphone; Methadone; Morphine; Neoplasms; Nurse's Role; Nursing Assessment; Oncology Nursing; Pain; Practice Guidelines as Topic; Therapeutic Equivalency; Treatment Outcome

2008
Pediatric palliative care: use of opioids for the management of pain.
    Paediatric drugs, 2009, Volume: 11, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Child; Delayed-Action Preparations; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Narcotics; Pain; Palliative Care

2009
Morphine to methadone conversion: an interpretation of published data.
    The American journal of hospice & palliative care, 2011, Volume: 28, Issue:2

    Topics: Analgesics, Opioid; Humans; Methadone; Morphine; Pain; Palliative Care; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu

2011
Buprenorphine treatment of opioid-dependent pregnant women: a comprehensive review.
    Addiction (Abingdon, England), 2012, Volume: 107 Suppl 1

    Topics: Buprenorphine; Child Development; Female; Fetus; Humans; Infant, Newborn; Length of Stay; Methadone; Milk, Human; Morphine; Narcotic Antagonists; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Pain Management; Patient Dropouts; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Randomized Controlled Trials as Topic; Substance Abuse Detection; Treatment Outcome

2012
Neonatal abstinence syndrome: therapeutic interventions.
    MCN. The American journal of maternal child nursing, 2013, Volume: 38, Issue:2

    Topics: Female; Humans; Infant; Infant Welfare; Infant, Newborn; Male; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Nursing Assessment; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Severity of Illness Index

2013
Pharmacologic management of neonatal abstinence syndrome in a community hospital.
    Clinical obstetrics and gynecology, 2013, Volume: 56, Issue:1

    Topics: Analgesics, Opioid; Female; Florida; Humans; Infant, Newborn; Intensive Care, Neonatal; Length of Stay; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications

2013
Management of neonatal abstinence syndrome from opioids.
    Clinics in perinatology, 2013, Volume: 40, Issue:3

    Topics: Analgesics, Opioid; Buprenorphine; Feeding Methods; Humans; Infant Care; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Pacifiers; Treatment Outcome

2013
Transdermal fentanyl for cancer pain.
    The Cochrane database of systematic reviews, 2013, Oct-05, Issue:10

    Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Methadone; Morphine; Neoplasms; Pain; Pain Measurement; Randomized Controlled Trials as Topic

2013
Maintenance agonist treatments for opiate-dependent pregnant women.
    The Cochrane database of systematic reviews, 2013, Dec-23, Issue:12

    Topics: Birth Weight; Buprenorphine; Delayed-Action Preparations; Female; Humans; Infant; Infant, Newborn; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Randomized Controlled Trials as Topic

2013
Behavioral effects of perinatal opioid exposure.
    Life sciences, 2014, May-28, Volume: 104, Issue:1-2

    Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Female; Humans; Illicit Drugs; Infant, Newborn; Male; Maternal Exposure; Maze Learning; Mental Disorders; Methadone; Mice; Morphine; Pain; Pregnancy; Rats; Sex Factors; Stress, Physiological

2014
[Analgesic management of acute pain in patients receiving methadone or buprenorphine].
    Ugeskrift for laeger, 2015, Mar-02, Volume: 177, Issue:10

    Topics: Acute Pain; Analgesics, Opioid; Buprenorphine; Drug Tolerance; Drug Users; Humans; Methadone; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Pain Management

2015
Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:6

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Drug Recalls; England; Heroin; Humans; Methadone; Morphine; Olanzapine; Poisoning; Quetiapine Fumarate; Thioridazine; Wales

2016
Pharmacotherapy for Neonatal Abstinence Syndrome: Choosing the Right Opioid or No Opioid at All.
    Neonatal network : NN, 2016, Volume: 35, Issue:5

    Topics: Analgesics; Buprenorphine; Clonidine; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Phenobarbital

2016
Neonatal Abstinence Syndrome.
    The New England journal of medicine, 2016, 12-22, Volume: 375, Issue:25

    Topics: Female; Humans; Incidence; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy; Pregnancy Complications

2016
Methadone for cancer pain.
    The Cochrane database of systematic reviews, 2017, 02-08, Volume: 2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Humans; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Pain Measurement; Randomized Controlled Trials as Topic

2017
[Treatment of acute pain in opioid addicts].
    Ugeskrift for laeger, 2017, Jun-26, Volume: 179, Issue:26

    Topics: Acute Pain; Analgesics, Opioid; Buprenorphine; Humans; Methadone; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Pain Management; Pain Measurement; Professional-Patient Relations

2017
Association of Rooming-in With Outcomes for Neonatal Abstinence Syndrome: A Systematic Review and Meta-analysis.
    JAMA pediatrics, 2018, 04-01, Volume: 172, Issue:4

    Topics: Analgesics, Opioid; Drug Utilization; Hospital Costs; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Rooming-in Care

2018
Methadone as anticancer treatment: hype, hope, or hazard? : A series of case reports and a short review of the current literature and recommendations of the societies.
    Wiener medizinische Wochenschrift (1946), 2018, Volume: 168, Issue:7-8

    Topics: Analgesics, Opioid; Austria; Female; Germany; Humans; Methadone; Middle Aged; Morphine; Neoplasms; Pain Management

2018
Neonatal Abstinence Syndrome: Advances in Diagnosis and Treatment.
    JAMA, 2018, Apr-03, Volume: 319, Issue:13

    Topics: Acupuncture Therapy; Analgesics; Breast Feeding; Buprenorphine; Clonidine; Female; Humans; Infant, Newborn; Methadone; Morphine; Mothers; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Rooming-in Care

2018
[Opioid switch and change of route of administration in cancer patients treated by morphine].
    Bulletin du cancer, 2018, Volume: 105, Issue:11

    Topics: Administration, Oral; Analgesics, Opioid; Breakthrough Pain; Cancer Pain; Drug Substitution; Fentanyl; France; Humans; Hydromorphone; Injections, Intravenous; Injections, Subcutaneous; Methadone; Morphine; Oxycodone; Phenols; Tapentadol

2018
Morphine and Methadone for Neonatal Abstinence Syndrome: A Systematic Review.
    Neonatal network : NN, 2018, Volume: 37, Issue:6

    Topics: Analgesics, Opioid; Female; Humans; Infant; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; United States

2018
Pharmacological and non-pharmacological treatments for the Neonatal Abstinence Syndrome (NAS).
    Seminars in fetal & neonatal medicine, 2019, Volume: 24, Issue:2

    Topics: Analgesics, Opioid; Breast Feeding; Buprenorphine; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome

2019
Slow release oral morphine versus methadone for the treatment of opioid use disorder.
    BMJ open, 2019, 04-02, Volume: 9, Issue:4

    Topics: Administration, Oral; Delayed-Action Preparations; Humans; Methadone; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Randomized Controlled Trials as Topic

2019
Comparative effectiveness of opioid replacement agents for neonatal opioid withdrawal syndrome: a systematic review and meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2019, Volume: 39, Issue:11

    Topics: Analgesics, Opioid; Buprenorphine; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment

2019
Methadone versus morphine treatment outcomes in neonatal abstinence syndrome: A meta-analysis.
    Journal of paediatrics and child health, 2019, Volume: 55, Issue:10

    Topics: Analgesics, Opioid; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Treatment Outcome

2019
Neonatal Abstinence Syndrome: Review of Epidemiology, Care Models, and Current Understanding of Outcomes.
    Clinics in perinatology, 2019, Volume: 46, Issue:4

    Topics: Analgesics, Opioid; Breast Feeding; Buprenorphine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Nurseries, Hospital; Opiate Substitution Treatment; Opioid-Related Disorders; Parents; Phenobarbital; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rooming-in Care; Severity of Illness Index; Treatment Outcome

2019
Why equianalgesic tables are only part of the answer to equianalgesia.
    Annals of palliative medicine, 2020, Volume: 9, Issue:2

    Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Dosage Calculations; Humans; Methadone; Morphine; Opioid Epidemic; Pain; Pain Management; Prescription Drug Misuse

2020
Maintenance agonist treatments for opiate-dependent pregnant women.
    The Cochrane database of systematic reviews, 2020, 11-09, Volume: 11

    Topics: Birth Weight; Buprenorphine; Delayed-Action Preparations; Female; Humans; Infant; Infant, Newborn; Methadone; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Dropouts; Pregnancy; Pregnancy Complications; Randomized Controlled Trials as Topic

2020
Quetiapine and other antipsychotics combined with opioids in legal autopsy cases: A random finding or cause of fatal outcome?
    Basic & clinical pharmacology & toxicology, 2021, Volume: 128, Issue:1

    Topics: Adolescent; Adult; Analgesics, Opioid; Animals; Antipsychotic Agents; Arrhythmias, Cardiac; Autopsy; Cause of Death; Consciousness; Drug Interactions; Drug Overdose; Female; Forensic Toxicology; Humans; Hypotension; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Quetiapine Fumarate; Respiratory Insufficiency; Risk Assessment; Risk Factors

2021
Opioid Treatment for Neonatal Opioid Withdrawal Syndrome: Current Challenges and Future Approaches.
    Journal of clinical pharmacology, 2021, Volume: 61, Issue:7

    Topics: Buprenorphine; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Methadone; Models, Biological; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders

2021
Methadone: applications in pediatric anesthesiology and critical care medicine.
    Journal of anesthesia, 2021, Volume: 35, Issue:1

    Topics: Analgesics, Opioid; Anesthesiology; Child; Critical Care; Humans; Methadone; Morphine

2021
Opioid treatment for opioid withdrawal in newborn infants.
    The Cochrane database of systematic reviews, 2021, 07-07, Volume: 7

    Topics: Buprenorphine; Chlorpromazine; Clonidine; Diazepam; Humans; Hypnotics and Sedatives; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Opium; Phenobarbital; Randomized Controlled Trials as Topic

2021
Psychosis after buprenorphine, heroin, methadone, morphine, oxycodone, and tramadol withdrawal: a systematic review.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:13

    Topics: Analgesics, Opioid; Buprenorphine; Heroin; Humans; Methadone; Morphine; Oxycodone; Psychotic Disorders; Substance Withdrawal Syndrome; Tramadol

2021
Methadone Switching for Cancer Pain: A New Classification of Initiation Protocols, Based on a Critical Literature Review.
    Journal of palliative medicine, 2021, Volume: 24, Issue:12

    Topics: Analgesics, Opioid; Cancer Pain; Humans; Methadone; Morphine; Neoplasms; Pain; Randomized Controlled Trials as Topic

2021
Relative effectiveness of medications for opioid-related disorders: A systematic review and network meta-analysis of randomized controlled trials.
    PloS one, 2022, Volume: 17, Issue:3

    Topics: Analgesics, Opioid; Buprenorphine; Humans; Methadone; Morphine; Naltrexone; Network Meta-Analysis; Opioid-Related Disorders; Randomized Controlled Trials as Topic

2022
Monitoring Prenatal Exposure to Buprenorphine and Methadone.
    Therapeutic drug monitoring, 2020, Volume: 42, Issue:2

    Topics: Analgesics, Opioid; Buprenorphine; Drug Monitoring; Female; Hair; Humans; Meconium; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Umbilical Cord

2020

Trials

115 trial(s) available for methadone and morphine

ArticleYear
Rx: 3x/week LAAM: alternative to methadone. Clinical studies: Phase I.
    NIDA research monograph, 1976, Issue:8

    Topics: Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Tolerance; Heroin; Heroin Dependence; Humans; Kinetics; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Patient Dropouts; Substance Withdrawal Syndrome; Time Factors

1976
Human pharmacology and abuse potential of the analgesic buprenorphine: a potential agent for treating narcotic addiction.
    Archives of general psychiatry, 1978, Volume: 35, Issue:4

    Topics: Adult; Blood Pressure; Buprenorphine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Euphoria; Humans; Male; Methadone; Middle Aged; Morphinans; Morphine; Naloxone; Narcotics; Pulse; Pupil; Receptors, Opioid; Substance Withdrawal Syndrome; Substance-Related Disorders

1978
Methadyl acetate and methadone. An open comparison.
    JAMA, 1977, Jan-10, Volume: 237, Issue:2

    Topics: Adult; Clinical Trials as Topic; Heroin Dependence; Humans; Male; Methadone; Methadyl Acetate; Middle Aged; Morphine; Substance Withdrawal Syndrome

1977
Analgesia in clinical practice.
    Scottish medical journal, 1977, Volume: 22, Issue:3

    Topics: Acetaminophen; Analgesia; Analgesics; Aspirin; Clinical Trials as Topic; Drug Interactions; Heroin; Humans; Methadone; Morphine; Nalorphine; Naloxone; Pentazocine

1977
Methadyl acetate versus methadone: the experience of one hospital.
    The Medical journal of Australia, 1977, Jul-30, Volume: 2, Issue:5

    Topics: Adult; Clinical Trials as Topic; Heroin Dependence; Humans; Illicit Drugs; Male; Methadone; Methadyl Acetate; Morphine; Patient Dropouts

1977
Preliminary observations with acute and chronic methadone and 1-alpha-acetylmethadol administration in humans.
    NIDA research monograph, 1976, Issue:8

    Topics: Clinical Trials as Topic; Drug Administration Schedule; Drug Tolerance; Female; Humans; Male; Methadone; Methadyl Acetate; Morphine; Substance-Related Disorders; Time Factors

1976
Summary of Veterans Administration Phase II cooperative study for LAAM and methadone.
    NIDA research monograph, 1976, Issue:8

    Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Heroin Dependence; Humans; Illicit Drugs; Male; Methadone; Methadyl Acetate; Middle Aged; Morphine; Patient Dropouts; Self Administration; United States; United States Department of Veterans Affairs

1976
Propranolol in the treatment of opiate dependence -- a controlled study.
    Psychopharmacologia, 1975, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Euphoria; Female; Heart Rate; Humans; Male; Methadone; Morphine; Morphine Dependence; Narcotic Antagonists; Placebos; Propranolol; Substance Withdrawal Syndrome; Substance-Related Disorders

1975
A double-blind randomised trial comparing postoperative analgesia after perioperative loading doses of methadone or morphine.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:1

    Topics: Adult; Analgesia; Double-Blind Method; Female; Heart Rate; Humans; Hysterectomy; Injections, Intravenous; Methadone; Morphine; Nausea; Oxygen; Pain Measurement; Pain, Postoperative; Premedication; Vomiting

1992
Comparison of morphine and methadone for prevention of postoperative pain in 3- to 7-year-old children.
    The Journal of pediatrics, 1991, Volume: 119, Issue:1 Pt 1

    Topics: Algorithms; Analysis of Variance; Child; Child, Preschool; Double-Blind Method; Drug Evaluation; Female; Humans; Intraoperative Care; Male; Methadone; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies

1991
Discordance between self-report and behavioral pain measures in children aged 3-7 years after surgery.
    Journal of pain and symptom management, 1990, Volume: 5, Issue:6

    Topics: Behavior; Child; Child, Preschool; Double-Blind Method; Humans; Interview, Psychological; Intraoperative Care; Methadone; Morphine; Pain Measurement; Pain, Postoperative

1990
Does intravenous methadone provide longer lasting analgesia than intravenous morphine? A randomized, double-blind study.
    Pain, 1989, Volume: 38, Issue:2

    Topics: Adult; Aged; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable

1989
Intrathecal methadone and morphine for postoperative analgesia: a comparison of the efficacy, duration, and side effects.
    Anesthesiology, 1989, Volume: 70, Issue:5

    Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Injections, Spinal; Male; Methadone; Middle Aged; Morphine; Pain, Postoperative; Random Allocation; Time Factors

1989
A comparative study of the efficacy and pharmacokinetics of oral methadone and morphine in the treatment of severe pain in patients with cancer.
    Pain, 1986, Volume: 25, Issue:3

    Topics: Administration, Oral; Aged; Biological Availability; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Half-Life; Humans; Infusions, Parenteral; Metabolic Clearance Rate; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Random Allocation

1986
Clonidine treatment of the opiate withdrawal syndrome. A review of clinical trials of a theory.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327

    Topics: Adrenergic Fibers; Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; Clonidine; Dextropropoxyphene; Drug Therapy, Combination; Heroin Dependence; Humans; Locus Coeruleus; Methadone; Morphine; Naltrexone; Narcotics; Norepinephrine; Rats; Substance Withdrawal Syndrome

1986
A randomized study on oral administration of morphine and methadone in the treatment of cancer pain.
    Journal of pain and symptom management, 1986,Fall, Volume: 1, Issue:4

    Topics: Administration, Oral; Clinical Trials as Topic; Female; Humans; Male; Methadone; Morphine; Neoplasms; Pain, Intractable; Random Allocation

1986
Comparison of intravenously administered methadone, morphine and heroin.
    Drug and alcohol dependence, 1986, Volume: 17, Issue:4

    Topics: Adult; Double-Blind Method; Euphoria; Heroin; Humans; Injections, Intravenous; Male; Methadone; Morphine; Pupil; Surveys and Questionnaires

1986
A double-blind comparison of the efficacy of methadone and morphine in postoperative pain control.
    Anesthesiology, 1986, Volume: 64, Issue:3

    Topics: Abdomen; Adult; Blood Specimen Collection; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Methadone; Middle Aged; Morphine; Pain; Postoperative Period; Time Factors

1986
Effects of diamorphine, methadone, morphine, and pentazocine in patients with suspected acute myocardial infarction.
    Lancet (London, England), 1969, May-31, Volume: 1, Issue:7605

    Topics: Acute Disease; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Female; Heart Rate; Heroin; Humans; Injections, Intravenous; Male; Methadone; Middle Aged; Morphine; Myocardial Infarction; Pain; Pentazocine; Respiration

1969
Studies on the relationship between 5-hydroxytryptamine turnover in brain and tolerance and physical dependence in mice.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 178, Issue:1

    Topics: Animals; Aspirin; Brain; Cyclazocine; Drug Tolerance; Fenclonine; Humans; Levorphanol; Male; Methadone; Mice; Morphinans; Morphine; Morphine Dependence; Nalorphine; Pargyline; Pentazocine; Phenylalanine; Physostigmine; Placebos; Serotonin; Substance Withdrawal Syndrome

1971
Methadone--a reevaluation.
    Archives of general psychiatry, 1973, Volume: 28, Issue:2

    Topics: Administration, Oral; Affect; Blood Pressure; Body Temperature; Dose-Response Relationship, Drug; Drug Tolerance; Electroencephalography; Humans; Injections, Subcutaneous; Male; Methadone; Morphine; Pituitary Function Tests; Pupil; Respiration; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders

1973
Levomethadyl in maintenance treatment of opiate dependence.
    JAMA, 1972, May-08, Volume: 220, Issue:6

    Topics: Adult; Alcohols; Amphetamine; Barbiturates; Benzene Derivatives; Heroin; Humans; Injections, Intravenous; Male; Methadone; Methylamines; Morphine; Substance Withdrawal Syndrome; Substance-Related Disorders

1972
Post-operative pain relief: comparison of methadone and morphine when used concurrently with nitrous-oxide analgesia.
    British medical journal, 1966, Sep-10, Volume: 2, Issue:5514

    Topics: Humans; Methadone; Morphine; Nitrous Oxide; Pain; Postoperative Care

1966
Comparison of four narcotic analgesics for extradural analgesia.
    British journal of anaesthesia, 1982, Volume: 54, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Epidural Space; Female; Fentanyl; Hemodynamics; Humans; Injections; Male; Meperidine; Methadone; Middle Aged; Morphine; Pain, Postoperative; Respiration; Time Factors

1982
Postoperative analgesia for Caesarean section using epidural methadone.
    Anaesthesia, 1984, Volume: 39, Issue:1

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Double-Blind Method; Epidural Space; Female; Humans; Injections; Methadone; Morphine; Pain, Postoperative; Pregnancy; Prospective Studies; Retrospective Studies

1984
Plasma levels and analgesia following deltoid and gluteal injections of methadone and morphine.
    Journal of clinical pharmacology, 1983, Volume: 23, Issue:1

    Topics: Adult; Analgesics; Biological Availability; Female; Humans; Injections, Intramuscular; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Postoperative

1983
Methadone and morphine in depression [proceedings].
    Psychopharmacology bulletin, 1981, Volume: 17, Issue:1

    Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Methadone; Middle Aged; Morphine

1981
Morphinelike arousal by methadone during sleep.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:6

    Topics: Adult; Arousal; Double-Blind Method; Humans; Male; Methadone; Middle Aged; Morphine; Muscle Contraction; Opioid-Related Disorders; Random Allocation; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors

1981
A comparison of intraoperative morphine sulfate and methadone hydrochloride on postoperative visual analogue scale pain scores and narcotic requirements.
    CRNA : the clinical forum for nurse anesthetists, 1995, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Intraoperative Care; Male; Methadone; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative

1995
Comparison of epidural methadone with epidural diamorphine for analgesia following caesarean section.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:4

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Cesarean Section; Double-Blind Method; Female; Heroin; Humans; Hypoxia; Incidence; Methadone; Morphine; Nausea; Oxygen; Pain Measurement; Pain, Postoperative; Pregnancy; Prochlorperazine; Pruritus; Time Factors

1993
Ventilatory effects of morphine, pethidine and methadone in children.
    British journal of anaesthesia, 1993, Volume: 70, Issue:4

    Topics: Child; Child, Preschool; Depression, Chemical; Female; Humans; Male; Meperidine; Methadone; Morphine; Oxygen; Pain, Postoperative; Respiration; Tidal Volume; Time Factors

1993
Comments on Ripamonti et al., Pain, 70 (1997) 109-115.
    Pain, 1997, Volume: 73, Issue:1

    Topics: Analgesics, Opioid; Humans; Methadone; Morphine; Pain, Intractable

1997
Overnight hospitalization after radical prostatectomy: the impact of two clinical pathways on patient satisfaction, length of hospitalization, and morbidity.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:1

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Humans; Length of Stay; Male; Methadone; Middle Aged; Morphine; Patient Satisfaction; Prostatectomy; Treatment Outcome

1998
Substitution with buprenorphine in methadone- and morphine sulfate-dependent patients. Preliminary results.
    European addiction research, 1998, Volume: 4 Suppl 1

    Topics: Adult; Buprenorphine; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Morphine; Narcotics; Opioid-Related Disorders

1998
Morphine versus methadone in the pain treatment of advanced-cancer patients followed up at home.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:11

    Topics: Adult; Aged; Analgesics, Opioid; Female; Home Care Services; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Prospective Studies

1998
Methadone titration in opioid-resistant cancer pain.
    European journal of cancer care, 1999, Volume: 8, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Drug Administration Schedule; Drug Resistance; Drug Tolerance; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Pain Measurement; Therapeutic Equivalency

1999
Comparison of methadone and slow-release morphine maintenance in pregnant addicts.
    Addiction (Abingdon, England), 1999, Volume: 94, Issue:2

    Topics: Adolescent; Adult; Delayed-Action Preparations; Female; Humans; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Pregnancy; Substance-Related Disorders

1999
Differences in the ratios of morphine to methadone in patients with neuropathic pain versus non-neuropathic pain.
    Journal of pain and symptom management, 1999, Volume: 18, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neuralgia; Pain

1999
The Swiss heroin trials. Scientifically sound?
    Journal of substance abuse treatment, 1999, Volume: 17, Issue:4

    Topics: Adult; Drug Prescriptions; Female; Heroin; Heroin Dependence; Humans; Male; Methadone; Morphine; Outcome and Process Assessment, Health Care; Research Design; Switzerland

1999
Slow-release morphine was not more effective than methadone in reducing neonatal abstinence syndrome.
    The Western journal of medicine, 2000, Volume: 172, Issue:1

    Topics: Adult; Delayed-Action Preparations; Female; Humans; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Pregnancy

2000
Patterns of opiate use in a heroin maintenance programme.
    Psychopharmacology, 2000, Volume: 152, Issue:1

    Topics: Adult; Age Factors; Anti-Anxiety Agents; Clorazepate Dipotassium; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; Morphine; Narcotics; Recurrence; Risk Factors

2000
Switching from morphine to methadone to improve analgesia and tolerability in cancer patients: a prospective study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jun-01, Volume: 19, Issue:11

    Topics: Administration, Oral; Analgesics, Opioid; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Prospective Studies

2001
Methadone maintenance patients are cross-tolerant to the antinociceptive effects of morphine.
    Pain, 2001, Volume: 93, Issue:2

    Topics: Acute Disease; Adult; Analgesics, Opioid; Cold Temperature; Drug Interactions; Drug Tolerance; Electric Stimulation; Female; Humans; Hyperalgesia; Injections, Intravenous; Male; Methadone; Morphine; Nociceptors; Pain Threshold

2001
[Withdrawal syndromes of newborns of pregnant drug abusers maintained under methadone or high-dose buprenorphine: 246 cases].
    Annales de medecine interne, 2001, Volume: 152 Suppl 7

    Topics: Analgesics, Opioid; Buprenorphine; Female; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Pregnancy; Pregnancy Complications; Prenatal Care; Prognosis; Prospective Studies; Substance-Related Disorders

2001
Pitfalls of opioid rotation: substituting another opioid for methadone in patients with cancer pain.
    Pain, 2002, Volume: 96, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Hydromorphone; Levorphanol; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Patient Satisfaction; Prospective Studies

2002
Postoperative pain relief after hepatic resection in cirrhotic patients: the efficacy of a single small dose of ketamine plus morphine epidurally.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:2

    Topics: Acetaminophen; Adult; Aged; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Anesthetics, Dissociative; Carcinoma, Hepatocellular; Female; Humans; Ketamine; Liver; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Male; Methadone; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies

2003
Comparative pharmacodynamics and pharmacokinetics of methadone and slow-release oral morphine for maintenance treatment of opioid dependence.
    Drug and alcohol dependence, 2003, Oct-24, Volume: 72, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Male; Methadone; Middle Aged; Morphine; Narcotic Antagonists; Opioid-Related Disorders

2003
Slow-release oral morphine versus methadone: a crossover comparison of patient outcomes and acceptability as maintenance pharmacotherapies for opioid dependence.
    Addiction (Abingdon, England), 2004, Volume: 99, Issue:8

    Topics: Adult; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Opioid-Related Disorders; Patient Satisfaction; Treatment Outcome

2004
Comparison of tincture of opium and methadone to control opioid withdrawal in a Thai treatment centre.
    British journal of clinical pharmacology, 2004, Volume: 58, Issue:5

    Topics: Administration, Oral; Adult; Humans; Methadone; Middle Aged; Morphine; Narcotics; Opioid-Related Disorders; Opium; Substance Withdrawal Syndrome

2004
Therapy of the neonatal abstinence syndrome with tincture of opium or morphine drops.
    Drug and alcohol dependence, 2005, Jan-07, Volume: 77, Issue:1

    Topics: Double-Blind Method; Female; Humans; Infant, Newborn; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opium; Pregnancy; Prenatal Exposure Delayed Effects

2005
The effect of intra-articular methadone on postoperative pain following anterior cruciate ligament reconstruction.
    The Journal of bone and joint surgery. American volume, 2005, Volume: 87, Issue:1

    Topics: Adult; Analgesics, Opioid; Anterior Cruciate Ligament; Arthroscopy; Female; Humans; Injections, Intra-Articular; Knee Joint; Male; Methadone; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies

2005
Randomized controlled study transitioning opioid-dependent pregnant women from short-acting morphine to buprenorphine or methadone.
    Drug and alcohol dependence, 2005, Apr-04, Volume: 78, Issue:1

    Topics: Adult; Buprenorphine; Double-Blind Method; Female; Humans; Methadone; Morphine; Opioid-Related Disorders; Pregnancy; Substance Withdrawal Syndrome

2005
Driving capacity of patients treated with methadone and slow-release oral morphine.
    Addiction (Abingdon, England), 2005, Volume: 100, Issue:7

    Topics: Adult; Analgesics, Opioid; Austria; Automobile Driving; Humans; Methadone; Morphine; Opioid-Related Disorders; Psychomotor Performance

2005
Comparative study of the effectiveness of slow-release morphine and methadone for opioid maintenance therapy.
    Addiction (Abingdon, England), 2005, Volume: 100, Issue:8

    Topics: Adult; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Methadone; Middle Aged; Morphine; Narcotic Antagonists; Opioid-Related Disorders; Time Factors; Treatment Outcome

2005
Opioid addicts at admission vs. slow-release oral morphine, methadone, and sublingual buprenorphine maintenance treatment participants.
    Substance use & misuse, 2006, Volume: 41, Issue:2

    Topics: Adult; Austria; Buprenorphine; Delayed-Action Preparations; Female; Humans; Male; Methadone; Morphine; Opioid-Related Disorders; Quality of Life; Substance Abuse Treatment Centers

2006
Methadone maintenance patients are cross-tolerant to the antinociceptive effects of very high plasma morphine concentrations.
    Pain, 2006, Volume: 120, Issue:3

    Topics: Adult; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Tolerance; Female; Humans; Injections, Intravenous; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Pain Threshold; Placebo Effect; Treatment Outcome

2006
Analgesic effects of subarachnoidally administered hyperbaric opioids in horses.
    American journal of veterinary research, 2006, Volume: 67, Issue:6

    Topics: Analgesia; Analgesics, Opioid; Animals; Buprenorphine; Cross-Over Studies; Female; Horse Diseases; Horses; Injections, Spinal; Male; Methadone; Morphine; Pain

2006
Mast cell mediator tryptase levels after inhalation or intravenous administration of high doses pharmaceutically prepared heroin.
    Drug and alcohol dependence, 2006, Dec-01, Volume: 85, Issue:3

    Topics: Administration, Inhalation; Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Heroin; Humans; Injections, Intravenous; Male; Methadone; Middle Aged; Morphine; Tryptases

2006
Opioid switching from morphine to methadone causes a minor but not clinically significant increase in QTc time: A prospective 9-month follow-up study.
    Journal of pain and symptom management, 2006, Volume: 32, Issue:2

    Topics: Aged; Analgesics, Opioid; Drug Administration Schedule; Electrocardiography; Female; Follow-Up Studies; Heart Rate; Humans; Long QT Syndrome; Male; Methadone; Middle Aged; Morphine; Prospective Studies; Risk Assessment; Risk Factors

2006
Hair analysis underestimates heroin use in prisoners.
    Drug and alcohol review, 2006, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Catchment Area, Health; Female; Follow-Up Studies; Hair; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; New South Wales; Prisoners; Prisons; Surveys and Questionnaires; Treatment Outcome

2006
Management of neonatal abstinence syndrome in neonates born to opioid maintained women.
    Drug and alcohol dependence, 2007, Mar-16, Volume: 87, Issue:2-3

    Topics: Adult; Apgar Score; Female; Gestational Age; Humans; Infant, Newborn; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Patient Selection; Phenobarbital; Pregnancy; Pregnancy Complications

2007
Methadone in the treatment of pain and terminal delirum in advanced cancer patients.
    Palliative & supportive care, 2005, Volume: 3, Issue:4

    Topics: Aged; Analgesics, Opioid; Delirium; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Neuropsychological Tests; Oxycodone; Pain; Pain Measurement; Palliative Care; Treatment Outcome

2005
Long term methadone for chronic pain: a pilot study of pharmacokinetic aspects.
    European journal of pain (London, England), 2007, Volume: 11, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Pain, Intractable; Pilot Projects; Time; Treatment Outcome

2007
Assessing the trade-offs between crossover and parallel group designs in sleep research.
    Journal of sleep research, 2006, Volume: 15, Issue:4

    Topics: Adult; Computer Graphics; Cross-Over Studies; Data Collection; Data Interpretation, Statistical; Female; Humans; Male; Mathematical Computing; Methadone; Morphine; Narcotics; Polysomnography; Research Design; Sleep

2006
The effect of opioids on sleep architecture.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2007, Feb-15, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Opioid-Related Disorders; Pain; Polysomnography; Sleep Apnea, Obstructive; Sleep Stages; Sleep, REM; Wakefulness

2007
Quality of life in patients receiving opioid maintenance therapy. A comparative study of slow-release morphine versus methadone treatment.
    European addiction research, 2008, Volume: 14, Issue:2

    Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Prospective Studies; Quality of Life

2008
Sustained-release oral morphine versus transdermal fentanyl and oral methadone in cancer pain management.
    European journal of pain (London, England), 2008, Volume: 12, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Patient Satisfaction; Prospective Studies; Quality of Life; Treatment Outcome

2008
The role of methadone in opioid rotation-a Polish experience.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2009, Volume: 17, Issue:5

    Topics: Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Poland; Severity of Illness Index; Treatment Outcome; Young Adult

2009
Comparative study on the sedative effects of morphine, methadone, butorphanol or tramadol, in combination with acepromazine, in dogs.
    Veterinary anaesthesia and analgesia, 2009, Volume: 36, Issue:1

    Topics: Acepromazine; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Body Temperature; Butorphanol; Cross-Over Studies; Dog Diseases; Dogs; Dopamine Antagonists; Drug Therapy, Combination; Hypnotics and Sedatives; Male; Methadone; Morphine; Tramadol; Vomiting

2009
Early switching from morphine to methadone is not improved by acetaminophen in the analgesia of oncologic patients: a prospective, randomized, double-blind, placebo-controlled study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Humans; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Prospective Studies; Young Adult

2010
Comparison of the cardio-respiratory effects of methadone and morphine in conscious dogs.
    Journal of veterinary pharmacology and therapeutics, 2009, Volume: 32, Issue:4

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Cardiovascular System; Dogs; Electrocardiography; Female; Hemodynamics; Infusions, Intravenous; Male; Methadone; Morphine; Respiratory System

2009
A double-blind, randomized, parallel group study to compare the efficacy, safety and tolerability of slow-release oral morphine versus methadone in opioid-dependent in-patients willing to undergo detoxification.
    Addiction (Abingdon, England), 2009, Volume: 104, Issue:9

    Topics: Adult; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome

2009
Neonatal abstinence syndrome after methadone or buprenorphine exposure.
    The New England journal of medicine, 2010, Dec-09, Volume: 363, Issue:24

    Topics: Adult; Buprenorphine; Double-Blind Method; Female; Head; History, Ancient; Humans; Infant, Newborn; Length of Stay; Logistic Models; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Pregnancy Complications

2010
How to switch from morphine or oxycodone to methadone in cancer patients? a randomised clinical phase II trial.
    European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:16

    Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Substitution; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Patient Dropouts; Prospective Studies

2011
Impact of treatment approach on maternal and neonatal outcome in pregnant opioid-maintained women.
    Human psychopharmacology, 2011, Volume: 26, Issue:6

    Topics: Adult; Austria; Birth Weight; Buprenorphine; Double-Blind Method; Female; Gestational Age; Humans; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, Third; Prospective Studies; Time Factors; Young Adult

2011
Serum concentrations of opioids when comparing two switching strategies to methadone for cancer pain.
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:8

    Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Morphine Derivatives; Neoplasms; Oxycodone; Pain; Palliative Care; Patient Dropouts

2012
Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in libido and insomnia in methadone maintenance patients.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:10

    Topics: Adult; Analgesics, Opioid; Benzodiazepines; Cohort Studies; Cross-Sectional Studies; Female; Genetic Association Studies; Heroin Dependence; Humans; Hypnotics and Sedatives; Libido; Male; Methadone; Morphine; Opiate Substitution Treatment; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Sexual Dysfunctions, Psychological; Sleep Initiation and Maintenance Disorders; Substance Abuse Detection; Substance Abuse Treatment Centers; Taiwan

2012
Feasibility of double-blind clinical trials with oral diacetylmorphine: a randomized controlled phase II study in an inpatient setting.
    European addiction research, 2012, Volume: 18, Issue:6

    Topics: Administration, Oral; Adult; Behavior, Addictive; Delayed-Action Preparations; Double-Blind Method; Feasibility Studies; Female; Heroin; Heroin Dependence; Humans; Inpatients; Male; Methadone; Morphine; Opiate Substitution Treatment; Physicians; Pilot Projects; Psychiatric Status Rating Scales

2012
Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2012, Volume: 7, Issue:4

    Topics: Adult; Amphetamine; Amphetamine-Related Disorders; Analgesics, Opioid; Central Nervous System Stimulants; Dextromethorphan; Double-Blind Method; Female; Heroin Dependence; Humans; Inflammation; Interleukin-8; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Secondary Prevention; Substance Abuse Detection; Tumor Necrosis Factor-alpha; Young Adult

2012
Predicting treatment for neonatal abstinence syndrome in infants born to women maintained on opioid agonist medication.
    Addiction (Abingdon, England), 2012, Volume: 107 Suppl 1

    Topics: Adolescent; Adult; Analgesics, Opioid; Birth Weight; Buprenorphine; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Length of Stay; Linear Models; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk Factors; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Smoking; Young Adult

2012
Neonatal neurobehavior effects following buprenorphine versus methadone exposure.
    Addiction (Abingdon, England), 2012, Volume: 107 Suppl 1

    Topics: Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Female; Humans; Infant Behavior; Infant, Newborn; Linear Models; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Severity of Illness Index; Young Adult

2012
Induction of pregnant women onto opioid-agonist maintenance medication: an analysis of withdrawal symptoms and study retention.
    Drug and alcohol dependence, 2013, Sep-01, Volume: 132, Issue:1-2

    Topics: Adult; Analysis of Variance; Buprenorphine; Confidence Intervals; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Educational Status; Ethnicity; Female; Humans; Linear Models; Methadone; Morphine; Narcotics; Patient Dropouts; Pregnancy; Pregnancy Complications; Socioeconomic Factors; Substance Withdrawal Syndrome

2013
Bioavailability of morphine, methadone, hydromorphone, and oxymorphone following buccal administration in cats.
    Journal of veterinary pharmacology and therapeutics, 2014, Volume: 37, Issue:3

    Topics: Administration, Buccal; Analgesics, Opioid; Animals; Biological Availability; Cats; Female; Hydromorphone; Methadone; Morphine; Oxymorphone

2014
Maintenance treatment for opioid dependence with slow-release oral morphine: a randomized cross-over, non-inferiority study versus methadone.
    Addiction (Abingdon, England), 2014, Volume: 109, Issue:4

    Topics: Administration, Oral; Adult; Codeine; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Maintenance Chemotherapy; Male; Medication Adherence; Methadone; Middle Aged; Morphine; Morphine Derivatives; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Treatment Outcome

2014
Methadone patient-controlled analgesia for postoperative pain: a randomized, controlled, double-blind study.
    Journal of anesthesia, 2014, Volume: 28, Issue:4

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Double-Blind Method; Female; Humans; Male; Methadone; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative

2014
Cardiorespiratory, sedative and antinociceptive effects of dexmedetomidine alone or in combination with methadone, morphine or tramadol in dogs.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:6

    Topics: Analgesia; Analgesics; Animals; Blood Pressure; Body Temperature; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Dogs; Drug Therapy, Combination; Female; Heart; Heart Rate; Male; Methadone; Morphine; Respiratory Physiological Phenomena; Respiratory Rate; Tramadol

2014
Safety and tolerability of slow-release oral morphine versus methadone in the treatment of opioid dependence.
    Journal of substance abuse treatment, 2014, Volume: 47, Issue:4

    Topics: Administration, Oral; Adult; Cross-Over Studies; Delayed-Action Preparations; Europe; Female; Humans; International Cooperation; Male; Methadone; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Treatment Outcome

2014
Methadone versus morphine for treatment of neonatal abstinence syndrome: a prospective randomized clinical trial.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:4

    Topics: Analgesics, Opioid; Birth Weight; Buprenorphine; Double-Blind Method; Female; Gestational Age; Humans; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Prospective Studies; Treatment Outcome

2015
Mental symptoms and drug use in maintenance treatment with slow-release oral morphine compared to methadone: results of a randomized crossover study.
    European addiction research, 2015, Volume: 21, Issue:2

    Topics: Administration, Oral; Adult; Alcohol Drinking; Behavioral Symptoms; Cross-Over Studies; Delayed-Action Preparations; Female; Germany; Humans; Male; Methadone; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Satisfaction; Substance-Related Disorders; Switzerland; Treatment Outcome; Young Adult

2015
Self-reported cravings for heroin and cocaine during maintenance treatment with slow-release oral morphine compared with methadone: a randomized, crossover clinical trial.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:2

    Topics: Adult; Cocaine-Related Disorders; Cross-Over Studies; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Opiate Substitution Treatment; Substance Withdrawal Syndrome; Surveys and Questionnaires; Treatment Outcome; Young Adult

2015
A placebo-controlled trial of dextromethorphan as an adjunct in opioid-dependent patients undergoing methadone maintenance treatment.
    The international journal of neuropsychopharmacology, 2015, Feb-25, Volume: 18, Issue:7

    Topics: Adult; Analgesics, Opioid; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Dextromethorphan; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Humans; Interleukin-6; Interleukin-8; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Retention, Psychology; Time Factors; Transforming Growth Factor beta1; Treatment Outcome; Tumor Necrosis Factor-alpha

2015
Effects of acepromazine-morphine and acepromazine-methadone premedication on the minimum alveolar concentration of isoflurane in dogs.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:1

    Topics: Acepromazine; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dogs; Female; Hysterectomy; Isoflurane; Methadone; Morphine; Ovariectomy; Premedication; Pulmonary Alveoli

2016
Sedative and cardiopulmonary effects of xylazine alone or in combination with methadone, morphine or tramadol in sheep.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:2

    Topics: Animals; Cardiovascular System; Cross-Over Studies; Drug Interactions; Female; Hypnotics and Sedatives; Methadone; Morphine; Prospective Studies; Respiratory System; Sheep; Tramadol; Xylazine

2016
Postoperative pain control in cats: clinical trials with pre-emptive lidocaine epidural co-administered with morphine or methadone.
    Journal of feline medicine and surgery, 2016, Volume: 18, Issue:11

    Topics: Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Animals; Cats; Drug Administration Schedule; Drug Therapy, Combination; Female; Hysterectomy; Injections, Epidural; Lidocaine; Methadone; Morphine; Ovariectomy; Pain Measurement; Pain, Postoperative; Treatment Outcome

2016
Switching Opioid-Dependent Patients From Methadone to Morphine: Safety, Tolerability, and Methadone Pharmacokinetics.
    Journal of clinical pharmacology, 2016, Volume: 56, Issue:8

    Topics: Adult; Analgesics, Opioid; Double-Blind Method; Drug Substitution; Female; Headache; Humans; Ibogaine; Male; Methadone; Morphine; Nausea; Opiate Substitution Treatment; Opioid-Related Disorders; Treatment Outcome

2016
Behavioral and cardiopulmonary effects of dexmedetomidine alone and in combination with butorphanol, methadone, morphine or tramadol in conscious sheep.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Animals; Butorphanol; Deep Sedation; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Male; Methadone; Morphine; Respiratory Rate; Sheep; Tramadol

2016
Comparison of medetomidine-morphine and medetomidine-methadone for sedation, isoflurane requirement and postoperative analgesia in dogs undergoing laparoscopy.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:1

    Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Combined; Animals; Cross-Over Studies; Dogs; Female; Isoflurane; Laparoscopy; Male; Medetomidine; Methadone; Morphine; Preanesthetic Medication; Propofol

2017
Effect of morphine, methadone, hydromorphone or oxymorphone on the thermal threshold, following intravenous or buccal administration to cats.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:6

    Topics: Administration, Buccal; Administration, Intravenous; Analgesics, Opioid; Animals; Cats; Cross-Over Studies; Female; Hydromorphone; Methadone; Morphine; Oxymorphone; Pain Threshold

2016
[Effects of morphine, butorphanol and levomethadone in different doses on thermal nociceptive thresholds in horses].
    Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 2017, Apr-19, Volume: 45, Issue:2

    Topics: Analgesics; Animals; Butorphanol; Horse Diseases; Horses; Hot Temperature; Methadone; Morphine; Pain; Pain Measurement

2017
Comparison of Safety and Efficacy of Methadone vs Morphine for Treatment of Neonatal Abstinence Syndrome: A Randomized Clinical Trial.
    JAMA pediatrics, 2018, 08-01, Volume: 172, Issue:8

    Topics: Analgesics, Opioid; Double-Blind Method; Female; Humans; Infant, Newborn; Intention to Treat Analysis; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Treatment Outcome

2018
The effect of methadone on postoperative quality of recovery in patients undergoing laparoscopic cholecystectomy: A prospective, randomized, double blinded, controlled clinical trial.
    Journal of clinical anesthesia, 2019, Volume: 53

    Topics: Adult; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Intravenous; Cholecystectomy, Laparoscopic; Female; Humans; Male; Methadone; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Prospective Studies; Remifentanil; Treatment Outcome; Young Adult

2019
A preoperative single dose of methadone for moderate-to-severely painful surgery reduces postoperative morphine consumption.
    Minerva anestesiologica, 2019, Volume: 85, Issue:10

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia; Double-Blind Method; Female; Fentanyl; Humans; Length of Stay; Male; Methadone; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Preoperative Care

2019
Methadone versus morphine for postoperative pain in patients undergoing surgery for gynecological cancer: A randomized controlled clinical trial.
    Journal of clinical anesthesia, 2020, Volume: 61

    Topics: Analgesics, Opioid; Female; Humans; Methadone; Morphine; Neoplasms; Pain Measurement; Pain, Postoperative

2020
Neurodevelopmental Outcomes of Neonates Randomized to Morphine or Methadone for Treatment of Neonatal Abstinence Syndrome.
    The Journal of pediatrics, 2020, Volume: 219

    Topics: Female; Humans; Infant; Infant, Newborn; Male; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Nervous System; Phenobarbital

2020
Slow release oral morphine versus methadone for opioid use disorder in the fentanyl era (pRESTO): Protocol for a non-inferiority randomized clinical trial.
    Contemporary clinical trials, 2020, Volume: 91

    Topics: Adult; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Overdose; Equivalence Trials as Topic; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Satisfaction; Quality of Life; Young Adult

2020
Methadone for postoperative analgesia: contribution of N-methyl-D-aspartate receptor antagonism: A randomised controlled trial.
    European journal of anaesthesiology, 2020, Volume: 37, Issue:10

    Topics: Analgesia; Analgesics, Opioid; Double-Blind Method; Humans; Methadone; Morphine; Pain, Postoperative; Prospective Studies; Receptors, N-Methyl-D-Aspartate

2020
Intra-operative methadone effect on quality of recovery compared with morphine following laparoscopic gastroplasty: a randomised controlled trial.
    Anaesthesia, 2021, Volume: 76, Issue:2

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia Recovery Period; Double-Blind Method; Female; Gastroplasty; Humans; Intraoperative Period; Laparoscopy; Male; Methadone; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Treatment Outcome

2021
Neonatal Abstinence Syndrome Severity Index Predicts 18-Month Neurodevelopmental Outcome in Neonates Randomized to Morphine or Methadone.
    The Journal of pediatrics, 2020, Volume: 227

    Topics: Analgesics, Opioid; Cluster Analysis; Female; Humans; Infant; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Severity of Illness Index

2020
Efficacy of methadone for the management of postoperative pain in laparoscopic cholecystectomy: A randomized clinical trial.
    Medwave, 2021, Mar-23, Volume: 21, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Intravenous; Cholecystectomy, Laparoscopic; Double-Blind Method; Humans; Methadone; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Treatment Outcome

2021
A Randomized Controlled Trial Evaluating the Analgesic Effect of the Combination of Methadone With Morphine for Cancer Related Pain.
    The Clinical journal of pain, 2021, 09-01, Volume: 37, Issue:9

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Humans; Methadone; Morphine; Neoplasms

2021
Morphine versus methadone for neonatal opioid withdrawal syndrome: a randomized controlled pilot study.
    BMC pediatrics, 2022, 06-15, Volume: 22, Issue:1

    Topics: Analgesics, Opioid; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Pilot Projects

2022
Pragmatic, randomized, blinded trial to shorten pharmacologic treatment of newborns with neonatal opioid withdrawal syndrome (NOWS).
    Trials, 2023, Jul-21, Volume: 24, Issue:1

    Topics: Analgesics, Opioid; Family; Female; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Research Design

2023
Correlations of maternal buprenorphine dose, buprenorphine, and metabolite concentrations in meconium with neonatal outcomes.
    Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:5

    Topics: Adult; Buprenorphine; Cocaine; Double-Blind Method; Female; Humans; Infant, Newborn; Male; Maternal Behavior; Maternal-Fetal Exchange; Meconium; Methadone; Narcotic Antagonists; Neonatal Abstinence Syndrome; Nicotine; Opiate Alkaloids; Opioid-Related Disorders; Pregnancy; Smoking

2008
Maternal methadone dose, placental methadone concentrations, and neonatal outcomes.
    Clinical chemistry, 2011, Volume: 57, Issue:3

    Topics: Analgesics, Opioid; Apgar Score; Birth Weight; Body Size; Cephalometry; Cocaine; Female; Gestational Age; Humans; Infant, Newborn; Maternal Exposure; Meconium; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimesters; Pyrrolidines; Tissue Distribution

2011
Methadone, cocaine, opiates, and metabolite disposition in umbilical cord and correlations to maternal methadone dose and neonatal outcomes.
    Therapeutic drug monitoring, 2011, Volume: 33, Issue:4

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Cocaine; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Methadone; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pyrrolidines; Umbilical Cord

2011

Other Studies

986 other study(ies) available for methadone and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
In silico design of novel probes for the atypical opioid receptor MRGPRX2.
    Nature chemical biology, 2017, Volume: 13, Issue:5

    Topics: Calcium; Cell Degranulation; Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mast Cells; Molecular Docking Simulation; Molecular Probes; Molecular Structure; Nerve Tissue Proteins; Pyrazoles; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Structure-Activity Relationship

2017
Effect of narcotic analgesics on the striatal homovanillic acid content in mice; relation to antinociceptive effect.
    Medical biology, 1976, Volume: 54, Issue:1

    Topics: Analgesics, Opioid; Animals; Body Temperature; Corpus Striatum; Cyclazocine; Haloperidol; Homovanillic Acid; Male; Methadone; Mice; Morphine; Pain; Pentazocine; Phenylacetates; Piperidines; Thebaine; Time Factors

1976
Schedule-induced narcotic ingestion.
    Pharmacological reviews, 1975, Volume: 27, Issue:4

    Topics: Analgesics, Opioid; Animals; Benzimidazoles; Conditioning, Operant; Diethylamines; Feeding Behavior; Food; Humans; Methadone; Morphine; Narcotics; Rats; Reinforcement Schedule; Reinforcement, Psychology; Self Mutilation; Time Factors; Water Deprivation

1975
Effect of blockade of 5-hydroxytryptamine re-uptake on drug-induced antinociception in the rat.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:5

    Topics: Analgesics; Animals; Brain; Depression, Chemical; Male; Meperidine; Methadone; Morphine; Phenyl Ethers; Propylamines; Rats; Reaction Time; Serotonin

1976
Interactions between narcotic analgesics and benzodiazepine derivatives on behavior in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzodiazepines; Brain; Brain Chemistry; Dextroamphetamine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Methadone; Methods; Mice; Morphine; Motor Activity; Naloxone; Oxazepam; Reaction Time

1976
Behavioral effects of narcotic analgesics administered alone or in combination with narcotic antagonists.
    Proceedings of the Western Pharmacology Society, 1976, Volume: 19

    Topics: Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Animal; Drug Interactions; Electroshock; Haplorhini; Macaca fascicularis; Methadone; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Time Factors

1976
Effects of narcotic analgesics on serotonin metabolism in brain of rats and mice.
    Japanese journal of pharmacology, 1976, Volume: 26, Issue:5

    Topics: Analgesics, Opioid; Animals; Atropine; Brain; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Mice; Mice, Inbred ICR; Morphine; Naloxone; Pargyline; Probenecid; Rats; Serotonin

1976
Characterization of (+/-)-methadone uptake by rat lung.
    British journal of pharmacology, 1977, Volume: 59, Issue:4

    Topics: Animals; Extracellular Space; Glucose; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Iodoacetates; Lung; Male; Methadone; Morphine; Naloxone; Oxygen; Rats; Sodium; Spectrometry, Fluorescence; Stereoisomerism; Time Factors

1977
The effect of 6-hydroxydopamine on the antinociceptive action of analgesics in mice.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:5

    Topics: Analgesics, Opioid; Animals; Drug Interactions; Female; Hydroxydopamines; Injections, Intraventricular; Levorphanol; Meperidine; Methadone; Mice; Morphine; Pentazocine; Reaction Time; Time Factors

1977
Analgesic drugs in the management of pain.
    Archives of surgery (Chicago, Ill. : 1960), 1977, Volume: 112, Issue:7

    Topics: Analgesics; Anti-Anxiety Agents; Aspirin; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Hypnotics and Sedatives; Ibuprofen; Indomethacin; Methadone; Morphine; Oxycodone; Pain; Pain, Intractable; Pentazocine; Pyrazoles

1977
Electric shock titration: effects of morphine, metadone, pentazocine, naloriphine, naloxone, diazepam and amphetamine.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:3

    Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Dextroamphetamine; Diazepam; Dose-Response Relationship, Drug; Electroshock; Haplorhini; Male; Methadone; Morphine; Naloxone; Narcotic Antagonists; Pentazocine; Saimiri

1977
Thin-layer detection of pentazocine, tripelennamine, phencyclidine and propoxyphene alone or in combination with opiates in drug abuse urine screening programs.
    Journal of chromatography, 1978, Aug-01, Volume: 155, Issue:1

    Topics: Analgesics, Opioid; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonists; Humans; Methadone; Methods; Morphine; Pentazocine; Phencyclidine; Quinine; Substance-Related Disorders; Tripelennamine

1978
Some considerations regarding the characterization and interpretation of neuropeptide-induced behavioral changes.
    Neurosciences Research Program bulletin, 1978, Volume: 16, Issue:4

    Topics: Animals; Behavior, Animal; Benzimidazoles; Dogs; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Haloperidol; Humans; Injections, Intravenous; Injections, Intraventricular; Methadone; Mice; Morphine; Motor Activity; Naloxone; Peptides; Rats; Time Factors

1978
Comparison of opiate- and opioid-peptide-induced immobility.
    Life sciences, 1979, Mar-05, Volume: 24, Issue:10

    Topics: Amygdala; Animals; Benzimidazoles; Brain; Caudate Nucleus; Endorphins; Enkephalins; Globus Pallidus; Injections; Injections, Intraventricular; Injections, Subcutaneous; Male; Methadone; Morphine; Motor Activity; Naloxone; Narcotics; Rats

1979
Immunologic effects of morphine administration in rabbits.
    Journal of immunology (Baltimore, Md. : 1950), 1975, Volume: 115, Issue:3

    Topics: Animals; Antibody Formation; Binding, Competitive; Carbon Radioisotopes; Carrier Proteins; Chemical Fractionation; Codeine; Cyclophosphamide; Drug Implants; Electrophoresis, Polyacrylamide Gel; Female; gamma-Globulins; Hemagglutination Tests; Hemocyanins; Heroin; Immunodiffusion; Levorphanol; Methadone; Morphine; Naloxone; Rabbits; Skin Tests

1975
Effect of morphine, hydromorphone, methadone, mescaline, trypan blue, vitamin A, sodium salicylate, and caffeine on the serum interferon level in response to viral infection.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:2

    Topics: Animals; Caffeine; Hydromorphone; Interferons; Male; Mescaline; Methadone; Mice; Morphine; Salicylates; Trypan Blue; Vesicular stomatitis Indiana virus; Virus Diseases; Vitamin A

1975
[Strong opiate analgesics for cancer pain].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979, Jul-10, Volume: 99, Issue:19-21

    Topics: Humans; Methadone; Morphine; Narcotics; Neoplasms; Palliative Care

1979
Behavioral supersensitivity to apomorphine following chronic narcotic treatment in the guinea pig.
    Psychopharmacology, 1978, May-31, Volume: 57, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Guinea Pigs; Haloperidol; Humans; Male; Methadone; Morphine; Stereotyped Behavior; Time Factors

1978
Analgetic actions of intrathecal opiates in cat and primate.
    Brain research, 1978, Sep-15, Volume: 153, Issue:1

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Electroshock; Escape Reaction; Female; Haplorhini; Injections, Spinal; Methadone; Morphine; Nociceptors; Reaction Time; Skin

1978
Drug metabolism by the fetal stump-tailed monkey (Macaca arctoides). Hepatic microsomal N-demethylation and glucuronidation as measured by radiometric assays.
    Pharmacology, 1979, Volume: 18, Issue:5

    Topics: Animals; Animals, Newborn; Cytochrome P-450 Enzyme System; Gestational Age; Glucuronidase; Haplorhini; Liver; Macaca; Meperidine; Methadone; Microsomes, Liver; Morphine; Organ Size; Oxidoreductases, N-Demethylating; Proteins

1979
Decrease in serum prolactin by naloxone: evidence against antidopamine and antipsychotic effects.
    The American journal of psychiatry, 1979, Volume: 136, Issue:10

    Topics: Animals; Haloperidol; Haplorhini; Humans; Macaca; Male; Methadone; Morphine; Naloxone; Opioid-Related Disorders; Prolactin; Psychotic Disorders; Receptors, Dopamine

1979
Effects of chronic treatment with morphine, methadone, and LAAM on the response to phencyclidine in rats.
    NIDA research monograph, 1979, Volume: 27

    Topics: Animals; Behavior, Animal; Drug Synergism; Humans; Male; Methadone; Methadyl Acetate; Morphine; Opioid-Related Disorders; Phencyclidine; Rats

1979
Dual action of morphine and related drugs on compulsive gnawing of rats.
    Psychopharmacologia, 1976, Volume: 46, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Compulsive Behavior; Female; Fenclonine; Humans; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Stereotyped Behavior; Thalamic Nuclei

1976
Immunologic effects of morphine in rodents, rabbits, monkeys, and cats.
    Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie, 1976, Volume: 151, Issue:2

    Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Blood; Cats; Codeine; Cross Reactions; Female; Guinea Pigs; Haplorhini; Haptens; Hemagglutination Tests; Immunodiffusion; Methadone; Morphine; Rabbits; Rats; Stereoisomerism

1976
Role of 5-hydroxytryptamine in morphine-, pethidine-, and methadone-induced hypothermia in rats at low ambient and room temperature.
    British journal of pharmacology, 1977, Volume: 60, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Cold Temperature; Depression, Chemical; Drug Interactions; Fenclonine; Male; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Temperature; Time Factors

1977
[Pharmacological analysis of the pendular movements appearing during calcium blocking of peristalsis in the isolated guinea pig ileum].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1977, Volume: 171, Issue:4

    Topics: Animals; Atropine; Calcium; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; Ileum; Methadone; Morphine; Muscle Contraction; Muscle, Smooth; Neostigmine; Peristalsis; Tetraethylammonium Compounds

1977
Changes in brain cyclic AMP metabolism and acetylcholine and dopamine during narcotic dependence and withdrawal.
    Life sciences, 1975, Jun-15, Volume: 16, Issue:12

    Topics: Acetylcholine; Acetylcholinesterase; Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Dopamine; Humans; Hypothalamus; Male; Mesencephalon; Methadone; Morphine; Naloxone; Protein Kinases; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Thalamus

1975
Effect of methadone on the male reproductive system.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 215, Issue:2

    Topics: Animals; Cyclic AMP; Male; Methadone; Mice; Morphine; Organ Size; Prostate; Seminal Vesicles; Testis

1975
Human sleep during chronic morphine intoxication.
    Psychopharmacologia, 1975, Oct-31, Volume: 44, Issue:2

    Topics: Adult; Alpha Rhythm; Arousal; Delta Rhythm; Drug Tolerance; Humans; Male; Methadone; Morphine; Morphine Dependence; Sleep; Sleep Stages; Sleep, REM; Substance Withdrawal Syndrome

1975
Studies on tolerance development to single doses of morphine in mice.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:2

    Topics: 5,6-Dihydroxytryptamine; Animals; Brain; Cyclic AMP; Cycloheximide; Drug Tolerance; Female; Humans; Hydroxydopamines; Male; Methadone; Mice; Morphine; Pain; Reaction Time; Substance-Related Disorders; Time Factors; Tryptophan

1976
The effects of narcotic analgesics and narcotic antagonists on ganglionic transmission in the rat.
    Life sciences, 1976, Aug-01, Volume: 19, Issue:3

    Topics: Animals; Ganglia, Autonomic; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Stereoisomerism; Synaptic Transmission

1976
The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists.
    Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:11

    Topics: Allosteric Regulation; Dextropropoxyphene; Fentanyl; Methadone; Models, Biological; Models, Molecular; Molecular Conformation; Morphine; Nalorphine; Naloxone; Narcotics; Pentazocine; Phenazocine; Protein Conformation; Receptors, Opioid; Structure-Activity Relationship

1976
Opioid peptides and opiates differ in receptor selectivity.
    Psychoneuroendocrinology, 1977, Volume: 2, Issue:1

    Topics: Animals; Brain; Dextrorphan; Endorphins; Enkephalins; Isomerism; Levorphanol; Methadone; Morphine; Naloxone; Naltrexone; Rats; Receptors, Opioid

1977
Opiate properties of SKF 525A.
    Canadian journal of physiology and pharmacology, 1978, Volume: 56, Issue:4

    Topics: Analgesia; Animals; Injections, Intraventricular; Male; Methadone; Morphine; Naloxone; Narcotics; Proadifen; Rats; Reaction Time; Receptors, Opioid

1978
Electroencephalographic and behavioral tolerance and cross-tolerance to morphine and methadone in the rat.
    Toxicology and applied pharmacology, 1978, Volume: 45, Issue:3

    Topics: Animals; Behavior, Animal; Drug Tolerance; Electroencephalography; Electromyography; Female; Methadone; Morphine; Rats; Sleep; Sleep, REM; Wakefulness

1978
An x-ray microanalysis study of differences in concentration of elements in brain cells due to opiates, cell type, and subcellular location.
    Journal of neuroscience research, 1978, Volume: 3, Issue:5-6

    Topics: Animals; Brain; Brain Chemistry; Calcium; Chlorides; Electron Probe Microanalysis; Ependyma; Female; Magnesium; Methadone; Microscopy, Electron, Scanning; Morphine; Naloxone; Neurons; Phosphorus; Potassium; Preoptic Area; Rats; Receptors, Opioid; Sodium; Subcellular Fractions; Sulfur

1978
Opioid self-administration and REM sleep EEG power spectra.
    NIDA research monograph, 1979, Volume: 27

    Topics: Animals; Electroencephalography; Female; Methadone; Methadyl Acetate; Morphine; Narcotics; Rats; Self Administration; Sleep, REM

1979
Etonitazine-induced rigidity and its antagonism by centrally acting muscle relaxants.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Analgesics, Opioid; Animals; Benzimidazoles; Benzyl Compounds; Catalepsy; Codeine; Cordotomy; Diethylamines; Fenclonine; Humans; Male; Methadone; Morphine; Muscle Relaxants, Central; Muscle Rigidity; Narcotic Antagonists; Rats; Time Factors

1975
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Dexetimide; Dextromoramide; Dogs; Dopamine; Drug Combinations; Haloperidol; Humans; Meperidine; Methadone; Mice; Morphine; Phenoperidine; Pimozide; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome; Tranquilizing Agents; Vomiting

1975
Opiate-specific displacement of steroid hormones from microsomes.
    Life sciences, 1975, Jun-15, Volume: 16, Issue:12

    Topics: Analgesics, Opioid; Animals; Binding, Competitive; Corticosterone; In Vitro Techniques; Male; Methadone; Microsomes, Liver; Morphine; Narcotic Antagonists; Progesterone; Rats; Receptors, Cell Surface; Receptors, Drug; Testosterone

1975
A study of the effect of d-amphetamine on the toxicity, analgesic potency and swimming impairment caused by potent analgesics in mice.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 216, Issue:2

    Topics: Analgesics, Opioid; Animals; Depression, Chemical; Dextroamphetamine; Drug Synergism; Lethal Dose 50; Male; Methadone; Mice; Morphine; Pentazocine; Physical Exertion; Reaction Time; Swimming; Temperature

1975
Opiates, prolactin, and the dopamine receptor.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:1

    Topics: Apomorphine; Bromocriptine; Chlorpromazine; Cyproheptadine; Heroin Dependence; Humans; Kinetics; Levodopa; Methadone; Morphine; Prolactin; Receptors, Dopamine

1978
Secretion of drugs by the parotid glands of rats and human beings.
    Journal of dental research, 1977, Volume: 56, Issue:5

    Topics: Acetylcholine; Adult; Amobarbital; Animals; Barbiturates; Chlorpromazine; Codeine; Glutethimide; Humans; Male; Meprobamate; Methadone; Morphine; Narcotics; Parotid Gland; Pentobarbital; Phenobarbital; Pilocarpine; Rats; Saliva; Secobarbital; Tranquilizing Agents

1977
Dual action of methadone on 5-HT synthesis and metabolism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 307, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine

1979
Specific conductivity of urine and sensitivity of enzyme immunoassay methods of analysis for drugs of abuse.
    Clinical chemistry, 1977, Volume: 23, Issue:4

    Topics: Amphetamine; Dextropropoxyphene; Diazepam; Electric Conductivity; Female; Humans; Immunoenzyme Techniques; Male; Methadone; Morphine; Sodium Chloride; Substance-Related Disorders; Urine

1977
Assessment of the EMIT-(TM) technique as a screening test for opiates and methadone for a methadone maintenance clinic and its calibration by Bayesian statistics.
    Clinical biochemistry, 1978, Volume: 11, Issue:5

    Topics: Chromatography, Thin Layer; Humans; Immunoenzyme Techniques; Mass Screening; Methadone; Morphine; Statistics as Topic

1978
Hepatic extraction of long- and short-acting narcotics in the isolated perfused rabbit liver.
    Gastroenterology, 1978, Volume: 75, Issue:1

    Topics: Animals; Biotransformation; Heroin; Liver; Liver Circulation; Meperidine; Methadone; Morphine; Narcotics; Rabbits; Time Factors

1978
Effects of morphine, methadone, nalorphine and naloxone on responding under schedules of electric shock titration.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:3

    Topics: Analgesics; Animals; Avoidance Learning; Electroshock; Escape Reaction; Haplorhini; Male; Methadone; Morphine; Nalorphine; Naloxone; Punishment; Saimiri

1977
Head-shake distributions during self-maintained dependence on morphine, methadone, and l-alpha-acetylmethadol (LAAM) in the rat.
    Psychopharmacology, 1977, Aug-31, Volume: 54, Issue:1

    Topics: Animals; Behavior, Animal; Female; Humans; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Rats; Self Administration; Substance-Related Disorders

1977
Effects of methadone and morphine maintenance on drug-seeking behavior in the dog.
    Psychopharmacology, 1977, Oct-20, Volume: 54, Issue:2

    Topics: Animals; Behavior, Animal; Dogs; Haplorhini; Humans; Methadone; Morphine; Papio; Rats; Self Administration; Substance Withdrawal Syndrome

1977
Self-administration of heroin, acetylmethadol, morphine, and methadone in rhesus monkeys.
    Life sciences, 1978, Volume: 22, Issue:7

    Topics: Animals; Behavior, Animal; Haplorhini; Heroin; Injections, Intravenous; Macaca mulatta; Methadone; Methadyl Acetate; Morphine; Narcotics; Respiration; Self Administration

1978
Effects of medial raphe and raphe magnus lesions on the analgesic activity of morphine and methadone.
    Psychopharmacology, 1978, Mar-01, Volume: 56, Issue:2

    Topics: Analgesics; Animals; Brain Chemistry; Brain Stem; Male; Methadone; Morphine; Raphe Nuclei; Rats; Reaction Time; Serotonin; Time Factors

1978
The effect of opiates on endogenous phosphorylation of proteins in the synaptic plasma membranes of rat striatum.
    Progress in clinical and biological research, 1979, Volume: 27

    Topics: Animals; Corpus Striatum; Drug Tolerance; Illicit Drugs; Male; Methadone; Morphine; Naloxone; Narcotics; Nerve Tissue Proteins; Phenytoin; Phosphorylation; Protein Kinases; Rats; Synaptic Membranes

1979
Analysis and differentiation of mechanism of tolerance to methadone in methadone-fed rats.
    Biochemical pharmacology, 1979, Volume: 28, Issue:2

    Topics: Analgesia; Animals; Drug Tolerance; Male; Methadone; Morphine; Phenobarbital; Rats; Tissue Distribution

1979
Improved method for morphine extraction from biological samples.
    Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:5

    Topics: Animals; Brain Chemistry; Chromatography, Thin Layer; Male; Methadone; Methods; Mice; Morphine; Naloxone

1979
Effect of narcotics on monoamine oxidase activity of mouse brain.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 24, Issue:1

    Topics: Animals; Brain; Kinetics; Levorphanol; Male; Methadone; Mice; Monoamine Oxidase; Morphine; Narcotics

1979
Discriminative stimulus properties of levo-alpha-acetylmethadol and its metabolites.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:4

    Topics: Animals; Discrimination, Psychological; Male; Methadone; Methadyl Acetate; Morphine; Rats; Time Factors

1979
Anti-cholinesterase activity of 1-alpha-acetylmethadol: relationship to bradycardia.
    General pharmacology, 1979, Volume: 10, Issue:3

    Topics: Acetylcholinesterase; Animals; Bethanechol Compounds; Bradycardia; Butyrylcholinesterase; Cholinesterase Inhibitors; Guinea Pigs; Heart Atria; Heart Rate; Methadone; Methadyl Acetate; Morphine; Myocardium; Physostigmine

1979
Naloxone-precipitated jumping in mice pretreated with acute injections of opioids.
    Life sciences, 1979, Aug-27, Volume: 25, Issue:9

    Topics: Animals; Behavior, Animal; Cyclazocine; Dose-Response Relationship, Drug; Enkephalins; Heroin; Male; Methadone; Methadyl Acetate; Mice; Morphine; Naloxone; Narcotics; Pentazocine

1979
Effect of methadone and morphine on serotonin uptake in rat periaqueductal gray slices.
    European journal of pharmacology, 1979, Oct-26, Volume: 59, Issue:1-2

    Topics: Animals; Brain; Cerebral Aqueduct; In Vitro Techniques; Male; Methadone; Morphine; Naloxone; Rats; Serotonin

1979
Drug-induced cues in studying mechanisms of drug action.
    Neuropharmacology, 1979, Volume: 18, Issue:12

    Topics: Animals; Cues; Drug Interactions; Electric Stimulation; Lysergic Acid Diethylamide; Male; Methadone; Methoxydimethyltryptamines; Morphine; Prejudice; Psychotropic Drugs; Raphe Nuclei; Rats; Receptors, Drug

1979
Behavioral effects in offspring of male mice injected with opioids prior to mating.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11 Suppl

    Topics: Animals; Avoidance Learning; Behavior, Animal; Electroshock; Fathers; Male; Methadone; Mice; Morphine; Narcotics; Swimming; Time Factors

1979
Analysis of reinforcement during intragastric self-administration of morphine and methadone in the rat.
    Communications in psychopharmacology, 1977, Volume: 1, Issue:1

    Topics: Animals; Humans; Intubation; Male; Methadone; Morphine; Morphine Dependence; Rats; Reinforcement, Psychology; Self Administration

1977
Tolerance and cross tolerance to toxic effects of morphine, methadone and 1-alpha-acetylmethadol (LAAM) in naive and morphine dependent rats.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:3

    Topics: Animals; Cross Reactions; Drug Tolerance; Female; Humans; Methadone; Methadyl Acetate; Morphine; Rats; Substance-Related Disorders

1978
Antidiuretic effect of morphine in the rat: tolerance and physical dependence.
    British journal of pharmacology, 1978, Volume: 64, Issue:2

    Topics: Animals; Diuresis; Drug Implants; Drug Tolerance; Humans; Injections, Intraperitoneal; Methadone; Morphine; Morphine Dependence; Naloxone; Rats; Sodium Chloride; Time Factors; Water

1978
Tolerance, dependence and lethality in morphine-dependent mice after repeated oral administration of methadone.
    Drug and alcohol dependence, 1978, Volume: 3, Issue:6

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Implants; Humans; Male; Methadone; Mice; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome

1978
Time course of dopaminergic hypersensitivity following chronic narcotic treatment.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:3

    Topics: Animals; Apomorphine; Dopamine; Guinea Pigs; Humans; Male; Methadone; Morphine; Narcotics; Stereotyped Behavior; Time Factors

1979
Development of cellular tolerance to lethality and analgesia concurrent with physical dependence following repeated oral administration of LAAM.
    Drug and alcohol dependence, 1979, Volume: 4, Issue:5

    Topics: Administration, Oral; Animals; Drug Tolerance; Humans; Injections, Intraventricular; Lethal Dose 50; Male; Methadone; Methadyl Acetate; Mice; Mice, Inbred ICR; Morphine; Naloxone; Nociceptors; Opioid-Related Disorders

1979
Dose-time motility effects of morphine and methadone in naive or morphinized rats.
    Pharmacological research communications, 1979, Volume: 11, Issue:9

    Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Male; Methadone; Morphine; Morphine Dependence; Motor Activity; Rats; Time Factors

1979
Comparing the effects of anileridine, alphaprodine and fentanyl on schedule-controlled responding by pigeons.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 206, Issue:3

    Topics: Alphaprodine; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Fentanyl; Isonipecotic Acids; Male; Methadone; Morphine; Naloxone; Reinforcement Schedule

1978
[Morphine intoxication and abstinence].
    Lakartidningen, 1977, Nov-30, Volume: 74, Issue:48

    Topics: Dextropropoxyphene; Drug Tolerance; Heroin; Heroin Dependence; Humans; Methadone; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome

1977
Morphine and methadone-induced antinociception in rats permanently depleted of brain dopamine.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 229, Issue:2

    Topics: Analgesics; Animals; Brain; Dopamine; Female; Hydroxydopamines; Methadone; Morphine; Norepinephrine; Pregnancy; Rats

1977
Pharmacologic activity of beta-endorphin in man.
    Communications in psychopharmacology, 1977, Volume: 1, Issue:5

    Topics: Analgesics; Dose-Response Relationship, Drug; Endorphins; Heroin Dependence; Humans; Methadone; Morphine; Pain, Intractable; Substance Withdrawal Syndrome

1977
Laboratory detection of morphine.
    Modern medicine of Asia, 1978, Volume: 14, Issue:6

    Topics: Amphetamines; Barbiturates; Humans; Indicators and Reagents; Methadone; Morphine

1978
Midbrain raphe mediation of the narcotic blockade of ovulation.
    Brain research, 1978, Oct-27, Volume: 155, Issue:2

    Topics: Animals; Brain Stem; Female; Luteinizing Hormone; Mesencephalon; Methadone; Morphine; Naltrexone; Ovulation; Raphe Nuclei; Rats

1978
Determination of drugs of abuse in body fluids by radioimmunoassay.
    Clinical biochemistry, 1978, Volume: 11, Issue:3

    Topics: Amphetamines; Barbiturates; Body Fluids; Cocaine; Humans; Lysergic Acid Diethylamide; Methadone; Methaqualone; Morphine; Radioimmunoassay; Substance-Related Disorders

1978
A comparative study on the behavioral response of offspring of female rats chronically treated with methadone and morphine.
    Proceedings of the Western Pharmacology Society, 1978, Volume: 21

    Topics: Animals; Avoidance Learning; Behavior, Animal; Female; Male; Methadone; Morphine; Motor Activity; Pregnancy; Rats; Sex Factors; Time Factors

1978
levo-Alpha-acetylmethadol and metabolites: some effects on schedule-controlled behavior in the rat.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:6

    Topics: Animals; Behavior, Animal; Male; Methadone; Methadyl Acetate; Morphine; Rats; Reinforcement Schedule; Time Factors

1978
Shattering myths about hospice care.
    American pharmacy, 1978, Volume: 18, Issue:12

    Topics: Hospices; Humans; Methadone; Morphine; Pain; Terminal Care

1978
Enhancement of morphine analgesia and brain levels by methamphetamine in mice.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 207, Issue:2

    Topics: Analgesia; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Drug Interactions; Male; Methadone; Methamphetamine; Mice; Morphine

1978
Interaction toxicity between ethanol and narcotics in mice with reference to alpha-1-acetylmethadol (LAAM).
    Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:2

    Topics: Animals; Brain; Dextrorphan; Drug Interactions; Ethanol; Lethal Dose 50; Levorphanol; Male; Methadone; Methadyl Acetate; Mice; Morphine; Narcotics

1978
Cardiopulmonary effects of narcotic agonists and a partial agonist in horses.
    American journal of veterinary research, 1978, Volume: 39, Issue:10

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Carotid Arteries; Heart Rate; Horses; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pentazocine; Respiration

1978
Effects of preexposure to morphine and pentobarbital on disposition of methadone in isolated rat livers.
    Toxicology and applied pharmacology, 1978, Volume: 45, Issue:3

    Topics: Animals; Bile; In Vitro Techniques; Liver; Male; Methadone; Morphine; Pentobarbital; Rats; Time Factors

1978
Comparative validity of random-interval and fixed-interval urinalysis schedules.
    Archives of general psychiatry, 1978, Volume: 35, Issue:3

    Topics: Appointments and Schedules; Diagnostic Errors; Heroin Dependence; Humans; Methadone; Morphine; Quinine; Time Factors; Urine

1978
Effects of d1-methadone and morphine on developing chick embryo.
    Experientia, 1978, Dec-15, Volume: 34, Issue:12

    Topics: Animals; Brain; Chick Embryo; Liver; Methadone; Morphine; Proteins

1978
Effects of morphine and methadone on the nuclear uptake of estradiol by the brain.
    Clinical toxicology, 1978, Volume: 13, Issue:3

    Topics: Animals; Autoradiography; Brain; Cell Nucleus; Estradiol; Female; Methadone; Morphine; Rats

1978
Drug use and employment patterns before and during treatment.
    The International journal of the addictions, 1978, Volume: 13, Issue:8

    Topics: Amphetamines; Barbiturates; Codeine; Demography; Employment; Humans; Methadone; Morphine; Outcome and Process Assessment, Health Care; Substance-Related Disorders

1978
Interference by NaCl with the EMIT method of analysis for drugs of abuse.
    Clinical chemistry, 1976, Volume: 22, Issue:11

    Topics: Chromatography, Thin Layer; False Negative Reactions; Humans; Immunoenzyme Techniques; Methadone; Morphine; Sodium Chloride; Substance-Related Disorders

1976
Immunosuppression of rosette-forming cells.
    Advances in experimental medicine and biology, 1976, Volume: 73 Pt B

    Topics: Amphetamine; Animals; Body Weight; Caffeine; Erythrocytes; Humans; Immunity; Immunologic Techniques; Immunosuppression Therapy; Leukocytes; Male; Methadone; Mice; Morphine; Organ Size; Pentobarbital; Phenobarbital; Sheep; Spleen; Substance-Related Disorders

1976
Comparison of immunogenicity of opiates bound to protein at different sites on the molecule: N-carboxy morphine-BSA.
    Pharmacological research communications, 1976, Volume: 8, Issue:3

    Topics: Animals; Antibody Specificity; Binding Sites; Carrier Proteins; Codeine; Haptens; Heroin; Immune Sera; Immunologic Techniques; Levorphanol; Methadone; Morphine; Morphine Derivatives; Naloxone; Protein Binding; Rabbits; Rats; Serum Albumin, Bovine; Structure-Activity Relationship

1976
Methadone maintenance.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adult; Deception; Evaluation Studies as Topic; Female; Health Expenditures; Heroin Dependence; Humans; Male; Methadone; Morphine; Patient Compliance; Research; Socioeconomic Factors; United States; United States Food and Drug Administration

1975
Characteristics of behavior controlled by scheduled injections of drugs.
    Pharmacological reviews, 1975, Volume: 27, Issue:3

    Topics: Animals; Barbiturates; Behavior, Animal; Cocaine; Drug Administration Schedule; Environment; Food; Haplorhini; Humans; Macaca mulatta; Methadone; Methohexital; Morphine; Pharmaceutical Preparations; Reinforcement Schedule; Saimiri; Substance-Related Disorders; Time Factors

1975
Drugs as reinforcers in monkey and man.
    Pharmacological reviews, 1975, Volume: 27, Issue:4

    Topics: Animals; Codeine; Disease Models, Animal; Drug Therapy; Haplorhini; Heroin Dependence; Humans; Legislation, Drug; Methadone; Morphine; Pentazocine; Reinforcement Schedule; Reinforcement, Psychology; Substance-Related Disorders; United States

1975
Evaluation of narcotic and narcotic antagonist interactions in primates.
    Annals of the New York Academy of Sciences, 1976, Volume: 281

    Topics: Animals; Cyclazocine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Female; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenytoin; Secobarbital; Self Administration

1976
Drug abuse proficiency testing.
    Clinical toxicology, 1977, Volume: 10, Issue:2

    Topics: Barbiturates; Cocaine; Dextroamphetamine; False Negative Reactions; Humans; Illicit Drugs; Laboratories; Methadone; Methamphetamine; Morphine; Pharmaceutical Preparations; Substance-Related Disorders; United States

1977
Meperidine effects on schedule-controlled responding.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 201, Issue:2

    Topics: Animals; Columbidae; Conditioning, Operant; Cyclazocine; Drug Interactions; Drug Tolerance; Male; Meperidine; Methadone; Morphine; Naloxone; Reaction Time; Reinforcement Schedule

1977
Cardiac effects of 1-alpha-acetylmethadol. I. Chronotropic effects in vitro.
    Toxicology and applied pharmacology, 1977, Volume: 40, Issue:1

    Topics: Animals; Drug Interactions; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Methacholine Compounds; Methadone; Methadyl Acetate; Morphine; Naloxone; Norepinephrine

1977
Binding of codeine, morphine, and methadone to human serum proteins.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:6

    Topics: Binding, Competitive; Blood Proteins; Codeine; Dialysis; Humans; Methadone; Morphine; Protein Binding; Serum Albumin

1977
The discriminative stimulus properties of morphine in female rats chronically depleted of dopamine.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 17, Issue:1

    Topics: Animals; Brain Chemistry; Discrimination Learning; Discrimination, Psychological; Dopamine; Dose-Response Relationship, Drug; Female; Generalization, Stimulus; Haloperidol; Methadone; Morphine; Norepinephrine; Rats; Stimulation, Chemical; Time Factors

1977
Toxic interactions of stimulants, narcotics and narcotic antagonists.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 17, Issue:2

    Topics: Animals; Cocaine; Cyclazocine; Dextroamphetamine; Drug Synergism; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats

1977
The effects of morphine-like drugs and chlorpromazine on the synthesis of glycerolipids by homogenates of rat liver.
    Biochemical Society transactions, 1977, Volume: 5, Issue:1

    Topics: Animals; Chlorpromazine; Glycerides; Glycerophosphates; Liver; Methadone; Morphine; Morphine Derivatives; Rats

1977
Calcium antagonist activity of methadone, l-acetylmethadol and l-pentazocine in the rat aortic strip.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:3

    Topics: Animals; Aorta, Thoracic; Calcium; Drug Interactions; In Vitro Techniques; Male; Methadone; Methadyl Acetate; Morphine; Muscle Contraction; Muscle, Smooth; Pentazocine; Rats; Stereoisomerism

1977
Barbital-induced changes in sensitivity to the behavioral effects of narcotics.
    Pharmacology, biochemistry, and behavior, 1977, Volume: 6, Issue:5

    Topics: Animals; Barbital; Barbiturates; Behavior, Animal; Conditioning, Operant; Drug Interactions; Drug Tolerance; Male; Methadone; Morphine; Rats; Reinforcement Schedule

1977
Quantum chemical studies of methadone.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:7

    Topics: Chemical Phenomena; Chemistry; Methadone; Models, Molecular; Molecular Conformation; Morphine; Quantum Theory

1976
A dose-response comparison between methadone and morphine self-administration.
    Psychopharmacologia, 1976, May-28, Volume: 47, Issue:2

    Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Humans; Male; Methadone; Morphine; Morphine Dependence; Rats

1976
Effects of acute and chronic methadone treatment of the uptake of 3H-5-hydroxytryptamine in rat hypothalamus slices.
    European journal of pharmacology, 1976, Volume: 36, Issue:2

    Topics: Animals; Dextrorphan; Female; Heroin; Humans; Hypothalamus; In Vitro Techniques; Levorphanol; Methadone; Morphine; Naloxone; Rats; Serotonin; Substance Withdrawal Syndrome; Time Factors

1976
Alteration by methadone of catecholamine uptake and release in isolated rat adrenomedullary storage vesicles.
    Life sciences, 1976, Aug-15, Volume: 19, Issue:4

    Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Biological Transport; Catecholamines; Cell-Free System; Kinetics; Male; Methadone; Morphine; Organoids; Rats; Reserpine; Temperature

1976
Morphine: ability to block neuronal activity evoked by a nociceptive stimulus.
    Life sciences, 1976, Sep-15, Volume: 19, Issue:6

    Topics: Action Potentials; Animals; Brain Stem; Chlorpromazine; Levorphanol; Male; Methadone; Morphine; Naloxone; Oxymorphone; Pain; Pentobarbital; Rats; Reticular Formation

1976
Long-acting narcotic antagonist complexes.
    National Institute on Drug Abuse research monograph series, 1976, Issue:4

    Topics: Animals; Brain; Diprenorphine; Methadone; Mice; Morphine; Naltrexone; Narcotic Antagonists; Reaction Time; Time Factors

1976
Blockade of the specific lethal effects of narcotic analgesics in the mouse.
    European journal of pharmacology, 1976, Volume: 39, Issue:2

    Topics: Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Lethal Dose 50; Male; Methadone; Mice; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Oxazepam; Trimethadione

1976
[Letter: Use of naloxone (Narcan) in poisoning by morphine, methadone and dextro propoxyphene].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Jun-20, Volume: 96, Issue:17-18

    Topics: Dextropropoxyphene; Humans; Methadone; Morphine; Naloxone; Poisoning; Suicide, Attempted

1976
Alterations in brain endogenous histamine levels in rats after chronic morphine treatment and morphine withdrawal.
    Agents and actions, 1976, Volume: 6, Issue:4

    Topics: Animals; Body Weight; Brain; Brain Stem; Cerebral Cortex; Histamine; Humans; Male; Methadone; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Time Factors

1976
Fallibility of urine drug screens in monitoring methadone programs.
    JAMA, 1976, Aug-30, Volume: 236, Issue:9

    Topics: Amphetamine; Cocaine; Heroin Dependence; Humans; Laboratories; Licensure; Methadone; Morphine; Pharmaceutical Preparations; Secobarbital; Substance-Related Disorders; United States

1976
Psychopathology and mood during heroin use: acute vs chronic effects.
    Archives of general psychiatry, 1976, Volume: 33, Issue:12

    Topics: Acute Disease; Adult; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emotions; Euphoria; Heroin; Heroin Dependence; Humans; Male; Methadone; Morphine; Motor Activity; Naloxone; Naltrexone; Psychopathology

1976
Interactions of narcotics, narcotic antagonists, and ethanol during acute, chronic, and withdrawal states.
    Annals of the New York Academy of Sciences, 1976, Volume: 281

    Topics: Alcohol Drinking; Animals; Animals, Newborn; Dextrorphan; Drug Interactions; Ethanol; Humans; Levorphanol; Male; Methadone; Methadyl Acetate; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1976
Microsomal enzyme induction by methadone and its implications on tolerance to methodone lethality.
    Nature, 1975, Jan-17, Volume: 253, Issue:5488

    Topics: Animals; Biotransformation; Drug Tolerance; Enzyme Induction; Lethal Dose 50; Liver; Methadone; Mice; Microsomes, Liver; Morphine; Organ Size; Oxidoreductases, N-Demethylating; Phenobarbital; Proteins

1975
Increased neonatal mortality in offspring of male rats treated with methadone or morphine before mating.
    Nature, 1975, Jan-17, Volume: 253, Issue:5488

    Topics: Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Male; Methadone; Morphine; Mortality; Rats; Spermatozoa; Time Factors

1975
Experience in the identification of abuse drugs in urines collected under Treatment Alternatives to Street Crime.
    Journal of forensic sciences, 1975, Volume: 20, Issue:1

    Topics: Amphetamine; Barbiturates; Charcoal; Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Crime; Electronic Data Processing; Forensic Medicine; Humans; Mass Screening; Methadone; Methamphetamine; Morphine; Pharmaceutical Preparations; Spectrometry, Fluorescence; Substance-Related Disorders

1975
Effects of narcotic antagonists on fluid intake in the rat.
    Life sciences, 1975, May-01, Volume: 16, Issue:9

    Topics: Amphetamine; Animals; Cyclazocine; Feeding Behavior; Male; Methadone; Methyltyrosines; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Pentazocine; Rats

1975
Accumulation of methadone by the choroid plexus in vitro.
    Neuropharmacology, 1975, Volume: 14, Issue:3

    Topics: Animals; Antimetabolites; Biological Transport; Calcium; Choroid Plexus; In Vitro Techniques; Magnesium; Male; Methadone; Morphine; Narcotic Antagonists; Phosphates; Rabbits; Time Factors; Verapamil

1975
Simultaneous detection of a wide variety of commonly abused drugs in a urine screening program using thin-layer identification techniques.
    Journal of chromatography, 1975, Apr-16, Volume: 107, Issue:2

    Topics: 1-Propanol; Ammonia; Ammonium Chloride; Amphetamine; Barbiturates; Chloroform; Chromatography, Thin Layer; Codeine; Humans; Hypnotics and Sedatives; Indicators and Reagents; Ion Exchange Resins; Methadone; Methamphetamine; Methylphenidate; Morphine; Opium; Phenmetrazine; Substance-Related Disorders

1975
Guidelines for the management of hospitalized narcotics addicts.
    Annals of internal medicine, 1975, Volume: 82, Issue:6

    Topics: Analgesia; Drug Administration Schedule; Drug Combinations; Drug Interactions; Female; Heroin; Hospitalization; Humans; Legislation, Drug; Male; Methadone; Morphine; Physician-Patient Relations; Pregnancy; Substance Withdrawal Syndrome; Substance-Related Disorders; United States

1975
Mechanism of development of tolerance to injected morphine by guinea pig ileum.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Acetylcholine; Animals; Drug Tolerance; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Methadone; Morphine; Muscle Contraction; Naloxone; Norepinephrine; Receptors, Drug; Serotonin; Time Factors

1975
[Effect of analgesics on artificial bimolecular phospholipid membranes].
    Doklady Akademii nauk SSSR, 1975, Apr-11, Issue:5

    Topics: Analgesics; Dextromoramide; Dose-Response Relationship, Drug; Fentanyl; Membranes, Artificial; Methadone; Morphine; Phospholipids; Piperidines

1975
Ligand-exchange chromatography of alkaloids.
    Journal of chromatography, 1975, Feb-12, Volume: 104, Issue:2

    Topics: Alkaloids; Atropine; Chromatography, Ion Exchange; Cinchona; Cinchona Alkaloids; Cocaine; Codeine; Copper; Hydrolysis; Ion Exchange Resins; Methadone; Methods; Morphine; Noscapine; Papaverine; Plants, Medicinal; Quinine; Strychnine

1975
Effect of loperamide, haloperidol and methadone in rats trained to discriminate morphine from saline.
    Psychopharmacologia, 1975, Volume: 41, Issue:3

    Topics: Animals; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Haloperidol; Male; Methadone; Morphine; Piperidines; Rats; Reinforcement Schedule; Sodium Chloride

1975
Rapid screening of street drugs by high pressure liquid chromatography: the screening of cocaine, heroin, methadone and morphine by reverse phase HPLC.
    Journal - Forensic Science Society, 1975, Volume: 15, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cocaine; Heroin; Methadone; Morphine

1975
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1

    Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Injections, Intraperitoneal; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotics; Pentazocine; Substance Withdrawal Syndrome

1975
Investigations on drug produced and subjectively experienced discriminative stimuli. 2. Loperamide, an antidiarrheal devoid of narcotic cue producing actions.
    Life sciences, 1975, Mar-01, Volume: 16, Issue:5

    Topics: Administration, Oral; Animals; Antidiarrheals; Codeine; Conditioning, Operant; Diphenoxylate; Discrimination Learning; Dose-Response Relationship, Drug; Fentanyl; Humans; Methadone; Morphine; Narcotics; Rats; Substance-Related Disorders; Time Factors

1975
The offset of morphine tolerance in rats and mice.
    British journal of pharmacology, 1975, Volume: 53, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Drug Tolerance; Humans; Methadone; Mice; Morphine; Morphine Dependence; Naloxone; Rats; Time Factors

1975
Renal toxicity of l-alpha-acetylmethadol (LAAM) in the rat.
    Proceedings of the Western Pharmacology Society, 1975, Volume: 18

    Topics: Animals; Hematuria; Kidney Diseases; Kidney Tubules; Methadone; Methadyl Acetate; Morphine; Naloxone; Nephrosis; Phenobarbital; Rats; Time Factors

1975
Screening for drug abuse: use of NaCl to increase drug recovery from papers coated with ion-exchange resin.
    Clinical chemistry, 1975, Volume: 21, Issue:12

    Topics: Amphetamine; Chlorpromazine; Chromatography, Paper; Humans; Ion Exchange Resins; Methadone; Morphine; Morphine Derivatives; Paper; Pentobarbital; Sodium Chloride; Substance-Related Disorders

1975
Binding of d-tubocurarine di (methyl-14C) ether iodide and other amines to cartilage, chondroitin sulfate and human plasma proteins.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:2

    Topics: Amines; Animals; Blood Proteins; Cartilage; Cattle; Chondroitin; Chondroitin Sulfates; Humans; In Vitro Techniques; Methadone; Morphine; Nasal Septum; Protein Binding; Tubocurarine

1975
Schedule-induced oral narcotic self-administration: acute and chronic effects.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:2

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Male; Methadone; Morphine; Narcotics; Rats; Reinforcement Schedule; Time Factors

1975
Duration of antinociceptive action of morphine, methadone and alpha-l-acetylmethadol subcutaneously in rats.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 12, Issue:4

    Topics: Analgesia; Animals; Injections, Subcutaneous; Male; Methadone; Methadyl Acetate; Morphine; Rats; Reaction Time; Time Factors; Vocalization, Animal

1975
The toxicology of twelve cases of death involving methadone: examination of postmortem specimens.
    Forensic science, 1975, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Autopsy; Diazepam; Ethanol; Female; Humans; Male; Methadone; Methaqualone; Morphine; Poisoning; Salicylates; Secobarbital

1975
Clinical experience with naltrexone.
    The American journal of drug and alcohol abuse, 1975, Volume: 2, Issue:3-4

    Topics: Administration, Oral; Adult; Female; Heroin Dependence; Hospitalization; Humans; Male; Methadone; Middle Aged; Morphine; Naloxone; Naltrexone; Outpatient Clinics, Hospital; Patient Dropouts; Placebos; Time Factors

1975
Long-acting narcotic antagonist complexes.
    National Institute on Drug Abuse research monograph series, 1975, Issue:4

    Topics: Aluminum; Animals; Brain; Buffers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diprenorphine; Drug Stability; Methadone; Mice; Morphine; Naltrexone; Narcotic Antagonists; Reaction Time; Zinc

1975
Effects of narcotic agonists and antagonists on schedule-induced water and morphine ingestion.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:2

    Topics: Animals; Cyclazocine; Drinking Behavior; Humans; Methadone; Morphine; Morphine Dependence; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Reinforcement Schedule

1975
Effects of morphine and methadone on serum testosterone and luteinizing hormone levels and on the secondary sex organs of the male rat.
    Endocrinology, 1976, Volume: 98, Issue:2

    Topics: Age Factors; Animals; Castration; Epididymis; Follicle Stimulating Hormone; Genitalia, Male; Hypophysectomy; Luteinizing Hormone; Male; Methadone; Morphine; Organ Size; Prostate; Rats; Seminal Vesicles; Testosterone

1976
Heroin addiction. Sequential treatment employing pharmacologic supports.
    Archives of general psychiatry, 1976, Volume: 33, Issue:3

    Topics: Heroin Dependence; Humans; Methadone; Morphine; Naltrexone; Prognosis; Recurrence

1976
Direct use of ion-exchange papers in hemagglutination-inhibition tests for drug abuse.
    Clinical chemistry, 1976, Volume: 22, Issue:7

    Topics: Aspirin; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Paper; Codeine; Hemagglutination Inhibition Tests; Humans; Methadone; Morphine; Nicotine; Phenobarbital; Substance-Related Disorders

1976
Agonist and antagonist activity of kappa opioids in the squirrel monkey: I. Antinociception and urine output.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzodiazepines; Benzomorphans; Drug Interactions; Ethylketocyclazocine; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nociceptors; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Urination

1992
Nonconventional opioid binding sites mediate growth inhibitory effects of methadone on human lung cancer cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Feb-15, Volume: 89, Issue:4

    Topics: Binding Sites; Calcium; Cell Death; Cell Division; Cell Membrane; Cyclic AMP; Cycloheximide; Dactinomycin; Growth Inhibitors; Humans; Methadone; Morphine; Naltrexone; Nicotine; Pertussis Toxin; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Stereoisomerism; Tumor Cells, Cultured; Virulence Factors, Bordetella

1992
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on ganglionic transmission.
    Journal of autonomic pharmacology, 1992, Volume: 12, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Electric Stimulation; Ganglia, Sympathetic; In Vitro Techniques; Male; Meperidine; Methadone; Morphine; Naloxone; Rats; Rats, Inbred Strains; Synaptic Transmission

1992
Effect of adrenal and sex hormones on opioid analgesia and opioid receptor regulation.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Analgesics; Animals; Brain; Female; Gonadal Steroid Hormones; Male; Methadone; Mice; Morphine; Naltrexone; Narcotics; Orchiectomy; Ovariectomy; Reaction Time; Receptors, Opioid; Sex Characteristics; Up-Regulation

1992
Sub-chronic exposure to opiates in the rat: effects on brain levels of substance P and calcitonin gene-related peptide during dependence and withdrawal.
    Journal of neuroscience research, 1992, Volume: 32, Issue:4

    Topics: Animals; Brain Chemistry; Calcitonin Gene-Related Peptide; Female; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Radioimmunoassay; Rats; Substance P; Substance Withdrawal Syndrome

1992
[Significance of drug determination in pilocarpine sweat for detection of past drug abuse].
    Beitrage zur gerichtlichen Medizin, 1992, Volume: 50

    Topics: Adult; Cocaine; Female; Humans; Illicit Drugs; Male; Methadone; Morphine; Pilocarpine; Psychotropic Drugs; Substance Abuse Detection; Sweat; Time Factors

1992
Immunological consequences of zidovudine treatment in control and morphine or methadone treated mice.
    Immunopharmacology and immunotoxicology, 1992, Volume: 14, Issue:3

    Topics: Animals; Cytotoxicity, Immunologic; Drug Interactions; Immune System; Killer Cells, Natural; Lymphocyte Activation; Male; Methadone; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Neutrophils; Phagocytosis; T-Lymphocyte Subsets; Zidovudine

1992
Morphine and methadone dependence in the rat: withdrawal and brain met-enkephalin levels.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Brain Chemistry; Drinking; Enkephalin, Methionine; Female; Methadone; Morphine; Morphine Dependence; Naloxone; Radioimmunoassay; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1992
Morphine dispensing to long term problematic injectors.
    British journal of addiction, 1992, Volume: 87, Issue:1

    Topics: Cause of Death; Drug Therapy, Combination; Follow-Up Studies; Humans; Methadone; Morphine; Netherlands; Opioid-Related Disorders; Substance Abuse, Intravenous

1992
The partial opioid agonist, buprenorphine, protects against lethal effects of cocaine.
    Drug and alcohol dependence, 1991, Volume: 27, Issue:2

    Topics: Animals; Brain; Buprenorphine; Cocaine; Dose-Response Relationship, Drug; Methadone; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Receptors, Opioid; Receptors, Opioid, mu; Seizures

1991
Onset of tolerance to discriminative stimulus effects of morphine.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:2

    Topics: Animals; Buprenorphine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Tolerance; Male; Methadone; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1991
Methadone dose and urine morphine.
    Journal of substance abuse treatment, 1991, Volume: 8, Issue:4

    Topics: Adult; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Heroin; Heroin Dependence; Humans; Male; Methadone; Morphine; Product Surveillance, Postmarketing; Substance Abuse Detection; Substance Abuse Treatment Centers

1991
Histamine release induced by opioid analgesics: a comparative study using porcine mast cells.
    Agents and actions, 1991, Volume: 33, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Histamine Release; Hydromorphone; Kidney; Liver; Lung; Mast Cells; Meperidine; Methadone; Morphine; Myocardium; Oxycodone; Swine

1991
[The analgesic action of d-phenylalanine in combination with morphine or methadone].
    Die Pharmazie, 1991, Volume: 46, Issue:12

    Topics: Action Potentials; Analgesics; Animals; Drug Interactions; Male; Methadone; Mice; Morphine; Pain Measurement; Phenylalanine; Rats; Rats, Inbred Strains

1991
Differential cross-tolerance to mu and kappa opioid agonists in morphine-tolerant rats responding under a schedule of food presentation.
    Psychopharmacology, 1991, Volume: 103, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Ethylketocyclazocine; Fentanyl; Food; Male; Methadone; Morphine; Naloxone; Narcotics; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule

1991
Acute and chronic morphine administration: effects of mixed-action opioids in rats and squirrel monkeys responding under a schedule of food presentation.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Tolerance; Male; Methadone; Morphine; Nalorphine; Naloxone; Rats; Receptors, Opioid; Saimiri; Species Specificity

1991
Treatment of severe cancer pain by continuous infusion of subcutaneous opioids.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1991, Volume: 121

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Pain Measurement

1991
The effect of prenatal methadone exposure of development and nociception during the early postnatal period of the rat.
    NIDA research monograph, 1990, Volume: 105

    Topics: Animals; Female; Methadone; Morphine; Nociceptors; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Reaction Time; Self Administration

1990
Differential cross-tolerance to opioids in squirrel monkeys responding under a shock titration schedule.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Cyclazocine; Drug Tolerance; Electroshock; Ethylketocyclazocine; Male; Methadone; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri

1990
Codeine O-demethylation: rat strain differences and the effects of inhibitors.
    Biochemical pharmacology, 1991, Mar-01, Volume: 41, Issue:5

    Topics: Animals; Codeine; Drug Interactions; Female; Kinetics; Methadone; Microsomes, Liver; Morphine; Oxidoreductases, O-Demethylating; Phenotype; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1991
Performance of techniques used to detect drugs of abuse in urine: study based on external quality assessment.
    Clinical chemistry, 1991, Volume: 37, Issue:3

    Topics: Amphetamine; Chromatography, Gas; Chromatography, Thin Layer; Cocaine; False Positive Reactions; Humans; Immunoassay; Methadone; Morphine; Quality Control

1991
Tolerance to morphine-like stimulus effects of mu opioid agonists.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2

    Topics: Animals; Buprenorphine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Etorphine; Male; Methadone; Morphine; Rats; Rats, Inbred Strains

1991
Intrathecal methadone: a dose-response study and comparison with intrathecal morphine 0.5 mg.
    Pain, 1990, Volume: 43, Issue:2

    Topics: Aged; Analgesia; Dose-Response Relationship, Drug; Humans; Injections, Spinal; Methadone; Middle Aged; Morphine; Pain Measurement; Time Factors

1990
Opioid agonist affinity in the guinea-pig ileum and mouse vas deferens.
    European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2

    Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Methadone; Mice; Morphine; Morphine Derivatives; Naltrexone; Receptors, Opioid; Vas Deferens

1990
Discriminative stimulus properties of U50,488 and morphine: effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Methadone; Morphine; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1990
The Amsterdam morphine-dispensing experiment.
    Medicine and law, 1990, Volume: 9, Issue:2

    Topics: Adult; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Methadone; Morphine; Netherlands; Substance Abuse Treatment Centers; Substance-Related Disorders

1990
Assessment of relative intrinsic activity of mu-opioid analgesics in vivo by using beta-funaltrexamine.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Fentanyl; Levorphanol; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Time Factors

1990
Central neurogenic hyperventilation: pharmacologic intervention with morphine sulfate and correlative analysis of respiratory, sleep, and ocular motor dysfunction.
    Neurology, 1990, Volume: 40, Issue:11

    Topics: Adult; Astrocytoma; Brain Neoplasms; Drug Therapy, Combination; Eye Movements; Female; Humans; Hyperventilation; Methadone; Morphine; Pons; Respiration; Saccades; Sleep

1990
Does intravenous methadone provide longer lasting analgesia than intravenous morphine?
    Pain, 1990, Volume: 42, Issue:3

    Topics: Analgesia; Humans; Injections, Intravenous; Methadone; Morphine; Time Factors

1990
Blockade of high K+ contractures and Ca(+)+-dependent slow action potentials in frog skeletal muscle by opioid drugs.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: Action Potentials; Animals; Calcium; Dextrorphan; Endorphins; In Vitro Techniques; Levorphanol; Methadone; Morphine; Muscle Contraction; Muscles; Narcotics; Potassium; Rana pipiens

1990
Epidural and intrathecal opiates: cerebrospinal fluid and plasma profiles in patients with chronic cancer pain.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:6

    Topics: Adult; Aged; beta-Endorphin; Drug Evaluation; Endorphins; Epidural Space; Female; Half-Life; Humans; Injections, Spinal; Kinetics; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Palliative Care

1985
I.v. infusion of opioids for cancer pain: clinical review and guidelines for use.
    Cancer treatment reports, 1986, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Administration Schedule; Drug Evaluation; Humans; Hydromorphone; Infant; Infusions, Parenteral; Levorphanol; Methadone; Middle Aged; Morphine; Narcotics; Neoplasms; Oxymorphone; Pain, Intractable; Palliative Care; Retrospective Studies

1986
Exceptionally high narcotic analgesic requirements in a terminally ill cancer patient.
    Clinical pharmacy, 1986, Volume: 5, Issue:10

    Topics: Adult; Analgesics, Opioid; Combined Modality Therapy; Drug Tolerance; Female; Humans; Hydromorphone; Methadone; Morphine; Neoplasms; Pain

1986
Unusual opioid withdrawal syndrome. A case-report.
    Lancet (London, England), 1987, Mar-28, Volume: 1, Issue:8535

    Topics: Aged; Colonic Neoplasms; Coma; Humans; Male; Methadone; Morphine; Neoplasm Recurrence, Local; Opium; Palliative Care; Receptors, Opioid; Substance Withdrawal Syndrome

1987
Sublingual absorption of selected opioid analgesics.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3

    Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Analysis of Variance; Biological Availability; Buprenorphine; Fentanyl; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Mouth; Naloxone; Oxycodone; Time Factors

1988
Suppression of human peripheral blood mononuclear cell function by methadone and morphine.
    The Journal of infectious diseases, 1989, Volume: 159, Issue:3

    Topics: Adult; Cells, Cultured; HIV Seropositivity; Humans; In Vitro Techniques; Interferon-gamma; Leukocytes, Mononuclear; Methadone; Middle Aged; Morphine; Naloxone; Superoxides; Tetradecanoylphorbol Acetate

1989
Intrathecal opioids, potency and lipophilicity.
    Pain, 1989, Volume: 36, Issue:1

    Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Endorphins; Injections, Spinal; Membrane Lipids; Meperidine; Methadone; Morphine; Morphine Derivatives; Nociceptors; Rats; Receptors, Opioid; Receptors, Opioid, mu; Solubility; Spinal Cord

1989
Differences in efficacies between morphine and methadone demonstrated in the guinea pig ileum: a possible explanation for previous observations on incomplete opioid cross-tolerance.
    Pharmacology & toxicology, 1989, Volume: 65, Issue:5

    Topics: Alkylation; Animals; Drug Tolerance; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Methadone; Morphine; Muscle, Smooth; Receptors, Opioid

1989
A new analysis of whole-body calorimetry data.
    NIDA research monograph, 1989, Volume: 95

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Body Temperature Regulation; Brain; Calorimetry; Methadone; Morphine; Oxygen Consumption; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1989
Effects of mixed-action opioids on food-maintained behavior of morphine-pretreated and morphine-tolerant rats.
    NIDA research monograph, 1989, Volume: 95

    Topics: Animals; Appetitive Behavior; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Methadone; Morphine; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule

1989
New differences between the Wistar rat and Octodon degus, a putative laboratory animal resistant to morphine.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1989, Volume: 93, Issue:2

    Topics: Adrenal Glands; Animals; Catecholamines; Drug Resistance; Electroencephalography; Ethanol; Female; Hemodynamics; In Vitro Techniques; Intestine, Small; Male; Methadone; Morphine; Naloxone; Rats; Rats, Inbred Strains; Respiration; Rodentia

1989
Fatal intoxications in the age group 15-34 years in Denmark in 1984 and 1985. A forensic study with special reference to drug addicts.
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1989, Volume: 103, Issue:2

    Topics: Adolescent; Adult; Analgesics, Opioid; Barbiturates; Cause of Death; Cross-Sectional Studies; Denmark; Dextropropoxyphene; Drug Overdose; Heroin; Humans; Incidence; Meperidine; Methadone; Morphine; Substance-Related Disorders

1989
Antiaversive properties of opioids in the conditioned taste aversion test in the rat.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:3

    Topics: Animals; Avoidance Learning; Conditioning, Classical; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Fentanyl; Male; Methadone; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Taste

1987
Evaluation of the effects of opioid agonists and antagonists under a delayed matching-to-sample procedure in pigeons.
    Psychopharmacology, 1987, Volume: 93, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Columbidae; Cyclazocine; Discrimination Learning; Endorphins; Ethylketocyclazocine; Female; Methadone; Morphine; Naloxone; Phencyclidine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma

1987
Orally administered kappa as well as mu opiate agonists delay gastrointestinal transit time in the guinea pig.
    Life sciences, 1988, Volume: 42, Issue:21

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Administration, Oral; Animals; Etorphine; Gastrointestinal Motility; Guinea Pigs; Male; Methadone; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1988
Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:3

    Topics: Animals; Benzomorphans; Caudate Nucleus; Dopamine; Male; Methadone; Morphine; Motor Activity; Naloxone; Naltrexone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Septal Nuclei

1988
Analeptic effect of opiate receptor agonists in rabbits.
    Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1

    Topics: Animals; Arousal; Brain; Central Nervous System Stimulants; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethylketocyclazocine; Etorphine; Male; Meperidine; Methadone; Morphine; Naltrexone; Narcotics; Phenazocine; Rabbits; Receptors, Opioid; Reflex

1985
5-HT-uptake inhibition potentiates antinociception induced by morphine, pethidine, methadone and ketobemidone in rats.
    Acta pharmacologica et toxicologica, 1985, Volume: 57, Issue:3

    Topics: Analgesics; Analgesics, Opioid; Animals; Brain; Citalopram; Drug Synergism; Male; Meperidine; Methadone; Morphine; Propylamines; Rats; Rats, Inbred Strains; Reaction Time; Serotonin; Serotonin Antagonists; Synaptosomes

1985
Differential cross-tolerance among morphine, methadone, and ethylketocyclazocine--EEG and behavior.
    NIDA research monograph, 1986, Volume: 67

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain; Cyclazocine; Drug Tolerance; Electroencephalography; Ethylketocyclazocine; Female; Methadone; Morphine; Rats; Rats, Inbred Strains

1986
Hallucination during sustained-release morphine and methadone administration.
    Lancet (London, England), 1987, Aug-15, Volume: 2, Issue:8555

    Topics: Delayed-Action Preparations; Hallucinations; Humans; Male; Methadone; Middle Aged; Morphine

1987
Prescribing for drug addicts.
    Lancet (London, England), 1987, Aug-22, Volume: 2, Issue:8556

    Topics: Drug Prescriptions; Heroin; Humans; Methadone; Morphine; Substance-Related Disorders

1987
Enhancement of opioid cataleptic response by cortical frontal deafferentation or intrastriatal injection of NMDA-receptor antagonists.
    Brain research, 1988, May-24, Volume: 449, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Catalepsy; Cerebral Cortex; Cerebral Ventricles; Corpus Striatum; Female; Kinetics; Methadone; Morphine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Valine

1988
Narcotic usage in renal failure.
    The International journal of artificial organs, 1988, Volume: 11, Issue:6

    Topics: Analgesics, Opioid; Codeine; Humans; Kidney Failure, Chronic; Methadone; Morphine

1988
Plasma arginine vasopressin response to intravenous methadone and naloxone in conscious dogs.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: Animals; Arginine Vasopressin; Blood Pressure; Dogs; Female; Heart Rate; Injections, Intravenous; Male; Methadone; Morphine; Naloxone

1989
High dose of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: clinical and theoretic implications.
    Anesthesiology, 1986, Volume: 64, Issue:5

    Topics: Anesthesia, Spinal; Animals; Blood Pressure; Cats; Drug Tolerance; Fentanyl; Hyperesthesia; Methadone; Morphine; Morphine Derivatives; Naltrexone; Rats; Receptors, Drug; Stimulation, Chemical; Strychnine; Sufentanil; Sulfates; Touch

1986
Crisis in drug testing. Results of CDC blind study.
    JAMA, 1985, Apr-26, Volume: 253, Issue:16

    Topics: Amphetamines; Barbiturates; Centers for Disease Control and Prevention, U.S.; Cocaine; Codeine; Diagnostic Errors; Humans; Illicit Drugs; Laboratories; Methadone; Morphine; Pharmaceutical Preparations; Quality Control; Research Design; United States

1985
Opioid activity of lefetamine.
    Pharmacological research communications, 1985, Volume: 17, Issue:5

    Topics: Anesthetics, Local; Animals; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Methionine; Ethylketocyclazocine; Lethal Dose 50; Male; Methadone; Mice; Morphine; Naloxone; Phenethylamines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid

1985
Maternal-fetal transfer of abused substances: pharmacokinetic and pharmacodynamic data.
    NIDA research monograph, 1985, Volume: 60

    Topics: Amphetamine; Animals; Cocaine; Dronabinol; Female; Fetus; Humans; Kinetics; Lysergic Acid Diethylamide; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Nicotine; Phencyclidine; Pregnancy; Substance-Related Disorders

1985
Opioid-hallucinogen interactions.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:2

    Topics: Animals; Brain Chemistry; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Hallucinogens; Liver; Lysergic Acid Diethylamide; Male; Methadone; Morphine; N,N-Dimethyltryptamine; Naloxone; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, mu; Stereoisomerism

1986
Use of beta-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Biological Assay; Buprenorphine; Butorphanol; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Etorphine; Fentanyl; Methadone; Mice; Morphine; Muscle Contraction; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, mu

1987
Methadone vs morphine: comparison of their effect on phagocytic functions.
    International journal of immunopharmacology, 1987, Volume: 9, Issue:1

    Topics: Animals; Candidiasis; Macrophages; Male; Methadone; Mice; Mononuclear Phagocyte System; Morphine; Neutrophils; Phagocytosis; Propionibacterium acnes; Pulmonary Alveoli; Superoxides

1987
Opioids and non-opioid enantiomers selectively attenuate N-methyl-D-aspartate neurotoxicity on cortical neurons.
    European journal of pharmacology, 1988, Oct-11, Volume: 155, Issue:1-2

    Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Indicators and Reagents; Methadone; Mice; Morphine; N-Methylaspartate; Naloxone; Narcotics; Neurons; Stereoisomerism

1988
Endocrine consequences of perinatal methadone exposure.
    NIDA research monograph, 1987, Volume: 78

    Topics: Aging; Animals; Animals, Newborn; Cyproheptadine; Disease Models, Animal; Hypothalamo-Hypophyseal System; Methadone; Morphine; Prolactin; Rats; Substance-Related Disorders

1987
Combined use of detomidine with opiates in the horse.
    Equine veterinary journal, 1988, Volume: 20, Issue:5

    Topics: Animals; Behavior, Animal; Blood Pressure; Butorphanol; Heart Rate; Horses; Hypnotics and Sedatives; Imidazoles; Meperidine; Methadone; Morphine; Narcotics; Pulmonary Gas Exchange

1988
Mechanisms of the contractile responses to morphine of the mouse colon in vitro.
    General pharmacology, 1988, Volume: 19, Issue:5

    Topics: Animals; Colon; In Vitro Techniques; Methadone; Mice; Morphine; Morphine Dependence; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Neostigmine; Serotonin Antagonists

1988
[3-step pharmacologic treatment of pain in cancer. Preliminary experience in Chile].
    Revista medica de Chile, 1988, Volume: 116, Issue:5

    Topics: Acetaminophen; Adult; Analgesics; Chile; Codeine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Pain Measurement

1988
Comparison of the discriminative stimulus properties of U50,488 and morphine in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Columbidae; Cyclazocine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Fentanyl; Methadone; Morphine; Naloxone; Phenazocine; Phencyclidine; Pyrrolidines; Time Factors

1987
Modification of the response to opioid and nonopioid drugs by chronic opioid antagonist treatment.
    Life sciences, 1988, Volume: 42, Issue:18

    Topics: Alprazolam; Analgesia; Animals; Ataxia; Cocaine; Drug Implants; Kinetics; Male; Methadone; Mice; Morphine; Naloxone; Narcotics

1988
Effects of opiates on the growth of neuron-enriched cultures from chick embryonic brain.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1986, Volume: 4, Issue:3

    Topics: Animals; Brain; Cells, Cultured; Chick Embryo; Choline O-Acetyltransferase; Dendrites; Methadone; Morphine; Narcotics

1986
Mechanism for the opioid-induced twitch potentiations of frog's skeletal muscle.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:7

    Topics: Animals; Calcium; Dextrorphan; Etorphine; In Vitro Techniques; Meperidine; Methadone; Morphine; Muscle Contraction; Muscles; Narcotics; Rana pipiens; Stimulation, Chemical

1986
Evaluation of the effects of opioid agonists and antagonists under a fixed-consecutive-number schedule in rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Conditioning, Operant; Cyclazocine; Discrimination Learning; Ethylketocyclazocine; Male; Methadone; Morphine; Naloxone; Narcotics; Phenazocine; Pyrrolidines; Rats; Reinforcement Schedule

1987
Changing the route of administration in children.
    Journal of pain and symptom management, 1986,Winter, Volume: 1, Issue:1

    Topics: Administration, Oral; Child; Female; Humans; Injections, Intravenous; Methadone; Morphine; Pain, Intractable; Patient Discharge

1986
The availability of narcotics and attitudes towards their use.
    Journal of pain and symptom management, 1986,Summer, Volume: 1, Issue:3

    Topics: Adrenal Gland Neoplasms; Child, Preschool; Female; Humans; Methadone; Morphine; Neuroblastoma; Pain

1986
Aspects of abstinence after morphine ingestion.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:1

    Topics: Animals; Body Weight; Diarrhea; Dose-Response Relationship, Drug; Drinking; Male; Methadone; Methods; Morphine; Morphine Dependence; Motor Activity; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Time Factors

1987
Morphine discrimination in the pigeon using a color tracking procedure.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Animals; Cocaine; Color; Columbidae; Cues; Cyclazocine; Dextroamphetamine; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Response; Male; Meperidine; Methadone; Morphine; Narcotics; Pentobarbital; Phencyclidine; Psychomotor Performance

1986
[Epidural analgesia with morphine and methadone].
    Harefuah, 1986, Feb-02, Volume: 110, Issue:3

    Topics: Anesthesia, Epidural; Animals; Humans; Methadone; Morphine

1986
The action of intrathecal morphine and methadone on the lower urinary tract in the dog.
    The Journal of urology, 1986, Volume: 135, Issue:4

    Topics: Animals; Compliance; Dogs; Female; Injections, Spinal; Methadone; Morphine; Muscle, Smooth; Pressure; Time Factors; Urethra; Urinary Bladder; Urodynamics

1986
A chronic sheep preparation for the study of drug pharmacokinetics in spinal and ventricular CSF.
    Journal of pharmacological methods, 1986, Volume: 16, Issue:4

    Topics: Animals; Cerebral Ventricles; Female; Infusions, Intravenous; Kinetics; Methadone; Models, Biological; Morphine; Pharmaceutical Preparations; Sheep; Spinal Cord; Subarachnoid Space; Sucrose

1986
CSF distribution of morphine, methadone and sucrose after intrathecal injection.
    Life sciences, 1985, Sep-23, Volume: 37, Issue:12

    Topics: Animals; Cisterna Magna; Dose-Response Relationship, Drug; Female; Injections, Spinal; Kinetics; Methadone; Morphine; Sheep; Sucrose

1985
Managing intractable pain with methadone (nursing grand rounds).
    Nursing, 1985, Volume: 15, Issue:5

    Topics: Adenocarcinoma; Female; Humans; Methadone; Middle Aged; Morphine; Pain, Intractable; Patient Care Planning

1985
Displacement of the surface membrane bound calcium of the skeletal muscle fibers of the frog: effects of lanthanum and opioids.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:1

    Topics: Animals; Binding Sites; Calcium; Cell Membrane; In Vitro Techniques; Lanthanum; Meperidine; Methadone; Morphine; Muscles; Narcotics; Rana pipiens

1985
The graded and quantal nature of opioid analgesia in the rat tailflick assay.
    Brain research, 1985, Apr-08, Volume: 331, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Kinetics; Male; Methadone; Morphine; Pain; Rats; Reaction Time

1985
Opiate-induced rhabdomyolysis.
    Human toxicology, 1985, Volume: 4, Issue:1

    Topics: Acute Kidney Injury; Adult; Aspartate Aminotransferases; Codeine; Creatine Kinase; Creatinine; Cyclizine; Drug Combinations; Female; Humans; Hypocalcemia; Male; Methadone; Middle Aged; Morphine; Myoglobin; Narcotics; Phosphates; Rhabdomyolysis; Suicide, Attempted

1985
Effects of acute and chronic morphine treatment on methadone analgesia and metabolism.
    European journal of pharmacology, 1985, Feb-12, Volume: 109, Issue:1

    Topics: Analgesics; Animals; Brain; Drug Implants; Drug Synergism; Liver; Male; Methadone; Morphine; Rats; Rats, Inbred Strains; Tissue Distribution

1985
Opiate self-administration in adult offspring of methadone-treated female rats.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:6

    Topics: Animals; Body Weight; Drinking; Female; Methadone; Morphine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Self Administration; Time Factors

1985
Cross-sensitization to the excitatory effect of morphine in post-dependent rats.
    Neuropharmacology, 1985, Volume: 24, Issue:9

    Topics: Animals; Male; Meperidine; Methadone; Morphine; Morphine Dependence; Motor Activity; Pentazocine; Rats; Rats, Inbred Strains; Time Factors

1985
Urinary function during epidural analgesia with methadone and morphine in post-cesarean section patients.
    Pain, 1985, Volume: 23, Issue:2

    Topics: Adult; Anesthesia, Epidural; Cesarean Section; Female; Humans; Methadone; Morphine; Pain, Postoperative; Postoperative Complications; Pregnancy; Urination; Urination Disorders

1985
Pharmacokinetics of morphine and its surrogates. VII: High-performance liquid chromatographic analyses and pharmacokinetics of methadone and its derived metabolites in dogs.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:11

    Topics: Animals; Bile; Biotransformation; Body Fluids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dogs; Hydrogen-Ion Concentration; Hydrolysis; Injections, Intravenous; Kinetics; Male; Methadone; Morphine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1985
-Globulin binding of morphine in heroin addicts.
    The Journal of laboratory and clinical medicine, 1972, Volume: 80, Issue:2

    Topics: Ammonium Sulfate; Animals; Antibody Formation; Centrifugation, Density Gradient; Chemical Precipitation; Chemistry Techniques, Analytical; Dialysis; Electrophoresis, Starch Gel; gamma-Globulins; Heroin; Humans; Immunodiffusion; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Methadone; Morphine; Protein Binding; Rabbits; Substance-Related Disorders; Sucrose; Tritium

1972
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
Rapid methods of screening micro-quantities of abused drugs from urine samples for microcrystal tests.
    Clinical toxicology, 1973, Volume: 6, Issue:3

    Topics: Acids; Alkalies; Alkaloids; Chromatography, Thin Layer; Codeine; Crystallization; Crystallography; Heroin Dependence; Humans; Hydromorphone; Indicators and Reagents; Meperidine; Methadone; Methods; Morphine; Nicotine; Quinine; Substance-Related Disorders

1973
Stereospecific uptake of narcotic analgesics by a subcellular fraction of the guinea-pig ileum. A preliminary communication.
    Upsala journal of medical sciences, 1973, Volume: 78, Issue:3

    Topics: Analgesics; Animals; Codeine; Dextromoramide; Female; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Intestinal Absorption; Levorphanol; Male; Methadone; Morphine; Muscle, Smooth; Nalorphine; Naloxone; Narcotics; Subcellular Fractions; Tritium

1973
Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amphetamine; Apomorphine; Barbiturates; Chromatography, Thin Layer; Cocaine; Codeine; Cross Reactions; Cyclazocine; Dextromethorphan; Dextropropoxyphene; Evaluation Studies as Topic; Hemagglutination Inhibition Tests; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Radioimmunoassay; Spectrometry, Fluorescence; Substance-Related Disorders; Time Factors; Tritium

1974
Contribution of 'receptor' affinity to analgesic potency.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: 1-Propanol; Analgesics; Animals; Binding, Competitive; Brain; Cyclopropanes; Fentanyl; Guinea Pigs; Hydromorphone; In Vitro Techniques; Injections, Intravenous; Levorphanol; Meperidine; Methadone; Morphinans; Morphine; Pentanols; Receptors, Drug

1974
[Analgesia in myocardial infarct].
    Zeitschrift fur Kardiologie, 1974, Volume: 63, Issue:12

    Topics: Analgesics; Diazepam; Heart; Hemodynamics; Heroin; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Myocardial Infarction; Nitrogen Oxides; Pain; Pentazocine; Respiration

1974
Inspiratory versus expiratory efforts in pigeons: a search for selective drug influence.
    Agents and actions, 1973, Volume: 3, Issue:4

    Topics: Anesthesia; Animals; Atropine; Barbiturates; Benzoates; Chloralose; Chlorpromazine; Codeine; Columbidae; Ethanol; Methadone; Methylphenidate; Morphine; Nalorphine; Nikethamide; Noscapine; Pregnanediones; Respiration; Trachea; Urethane

1973
Antagonism of acute lethality of narcotic analgesics in aggregated and isolated mice by the central cholinomimetic action of pilocarpine.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 210, Issue:2

    Topics: Analgesics, Opioid; Animals; Atropine; Atropine Derivatives; Crowding; Depression, Chemical; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Motor Activity; Parasympathomimetics; Pentazocine; Pilocarpine; Social Isolation; Stimulation, Chemical; Time Factors

1974
[Ionization constants of several narcotic analgesics and their pain relieving activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:3

    Topics: Analgesics, Opioid; Benzilates; Chemical Phenomena; Chemistry, Physical; Codeine; Dextromoramide; Dimethylamines; Kinetics; Levorphanol; Meperidine; Methadone; Morphine; Muscle Relaxants, Central; Phenylacetates; Structure-Activity Relationship

1973
Changing patterns of drug abuse in New York City.
    The American journal of drug and alcohol abuse, 1974, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Antipsychotic Agents; Barbiturates; Codeine; Dextropropoxyphene; Female; Glutethimide; Heroin Dependence; Humans; Male; Methadone; Morphine; New York City; Phenothiazines; Phenytoin; Quinine; Substance-Related Disorders

1974
Narcotic blockade.
    Archives of internal medicine, 1966, Volume: 118, Issue:4

    Topics: Drug Tolerance; Follow-Up Studies; Heroin; Humans; Hydromorphone; Injections, Intravenous; Methadone; Morphine; Rehabilitation; Substance Withdrawal Syndrome; Substance-Related Disorders

1966
Narcotic blockade--a medical technique for stopping heroin use by addicts.
    Transactions of the Association of American Physicians, 1966, Volume: 79

    Topics: Euphoria; Heroin; Humans; Hydromorphone; Methadone; Morphine; Substance Withdrawal Syndrome; Substance-Related Disorders

1966
Urine screening techniques employed in the detection of users of narcotics and their correlation with the nalorphine test.
    Journal of forensic sciences, 1966, Volume: 11, Issue:2

    Topics: Amphetamine; California; Cocaine; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Nalorphine; Pupil; Substance-Related Disorders

1966
Tolerance to the lenticular effects of opiates.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:1

    Topics: Animals; Dactinomycin; Drug Tolerance; Epinephrine; Female; Lens, Crystalline; Levorphanol; Methadone; Mice; Morphine; Puromycin; Reserpine

1967
Heroin and cocaine addiction.
    Lancet (London, England), 1965, Apr-10, Volume: 1, Issue:7389

    Topics: Adolescent; Adult; Amphetamine; Barbiturates; Cannabis; Cocaine; Dextroamphetamine; Ethanol; Female; Follow-Up Studies; Heroin; Hospitalization; Hospitals, Psychiatric; Humans; Injections, Intravenous; Male; Methadone; Morphine; Substance Withdrawal Syndrome; Substance-Related Disorders; United Kingdom; United States

1965
Interactions of narcotics and their antagonists with human serum esterase. II: nature of the antagonism.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 164, Issue:1

    Topics: Drug Antagonism; Enzymes; Esterases; Humans; Hydromorphone; Levorphanol; Methadone; Models, Theoretical; Morphine; Nalorphine; Narcotic Antagonists; Procaine; Spectrophotometry

1966
Interactions of narcotics and their antagonists with human serum esterase. I: sites of action and nature of the inhibitory effect.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 164, Issue:1

    Topics: Drug Antagonism; Drug Synergism; Enzymes; Esterases; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Procaine; Spectrophotometry

1966
A method of identifying narcotic analgesics in human urine after therapeutic doses.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Alkaloids; Analgesics; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Humans; Hydromorphone; Ion Exchange; Levorphanol; Meperidine; Methadone; Methods; Morphine; Narcotics; Pentazocine

1970
[Permeation of active morphine-like substances at their sites of antinociceptive action in the brain as a function of their lipid-solubility following intravenous and intraventricular application].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 265, Issue:5

    Topics: Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Dental Pulp Test; Fentanyl; Hydromorphone; Ketones; Kinetics; Levorphanol; Lipids; Methadone; Morphinans; Morphine; Piperidines; Rabbits; Solubility; Tritium

1970
Application of enzyme kinetics to a problem in pharmacology: receptor affinities and efficacies in the action of morphine and related drugs on human serum esterase.
    Enzymologia, 1970, May-31, Volume: 38, Issue:5

    Topics: Esterases; Hydromorphone; Kinetics; Levorphanol; Mathematics; Metabolism; Methadone; Morphine; Nalorphine

1970
Effects of opioid narcotic drugs on energy reserves of skeletal muscle. I. Glycogen.
    Biochemical pharmacology, 1974, Feb-01, Volume: 23, Issue:3

    Topics: Animals; Calcium; Carbon Radioisotopes; Diaphragm; Drug Tolerance; Energy Metabolism; Epinephrine; Glucose; Glycogen; Glycogen Synthase; In Vitro Techniques; Male; Meperidine; Methadone; Morphinans; Morphine; Muscles; Narcotics; Phosphoglucomutase; Phosphorylases; Propranolol; Rats; Time Factors

1974
[Behavioral changes and relationships and electrocorticograms induced in the rabbit by prolonged administration of morphine analgesics].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1966, Volume: 160, Issue:11

    Topics: Animals; Behavior, Animal; Brain; Electroencephalography; Methadone; Morphine; Rabbits

1966
Suppression of craving and other signs of dependence in morphine-addicted monkeys by administration of alpha-methyl-para-tyrosine.
    Mayo Clinic proceedings, 1972, Volume: 47, Issue:9

    Topics: Animals; Female; Fenclonine; Haloperidol; Haplorhini; Humans; Hypothalamus; Injections, Intravenous; Macaca; Methadone; Methyltyrosines; Morphine; Nalorphine; Septal Nuclei; Substance Withdrawal Syndrome; Substance-Related Disorders; Thioridazine; Trifluoperazine

1972
5-hydroxytryptamine in platelets and brain of rabbits treated chronically with imipramine, morphine or methadone.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 277, Issue:4

    Topics: Animals; Blood Platelets; Brain Chemistry; Hydroxyindoleacetic Acid; Imipramine; Male; Methadone; Morphine; Rabbits; Serotonin; Time Factors

1973
Proceedings: A simple model for the assessment of analgetic tolerance in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Analgesics; Animals; Drug Tolerance; Methadone; Models, Biological; Morphine; Pressure; Rats; Time Factors

1974
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
    British journal of pharmacology, 1974, Volume: 51, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus

1974
Hyposensitivity to drugs induced by morphine and some related substances in the cat.
    British journal of pharmacology, 1970, Volume: 39, Issue:4

    Topics: Angiotensin II; Animals; Blood Pressure; Cats; Epinephrine; Female; Meperidine; Methadone; Morphine; Muscle, Smooth; Nalorphine; Nictitating Membrane; Norepinephrine; Tachyphylaxis; Uterus; Venous Pressure

1970
Liquid-solid extraction of lyophilized biological materials for forensic analysis. II. Application to bile samples for the detection of drugs.
    Journal of chromatography, 1972, Mar-22, Volume: 66, Issue:1

    Topics: Bile; Chromatography, Thin Layer; Fluorometry; Forensic Medicine; Freeze Drying; Gels; Humans; Hydrogen-Ion Concentration; Methadone; Methods; Morphine; Silicon Dioxide

1972
Spin immunoassay of opiate narcotics in urine and saliva.
    JAMA, 1972, Sep-11, Volume: 221, Issue:11

    Topics: Animals; Antibody Formation; Chromatography, Thin Layer; Electron Spin Resonance Spectroscopy; Free Radicals; Goats; Haptens; Humans; Immunoassay; Methadone; Methods; Morphine; Opium; Rabbits; Saliva; Structure-Activity Relationship; Substance-Related Disorders

1972
Interferon inhibition by narcotic analgesics.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:1

    Topics: Animals; Body Temperature; Depression, Chemical; Diverticulum, Colon; Dose-Response Relationship, Drug; Endotoxins; Interferon Inducers; Interferons; L Cells; Male; Methadone; Mice; Morphine; Poly I-C; Vesicular stomatitis Indiana virus

1973
Homogenous immunochemical drug assays.
    The American journal of medical technology, 1973, Volume: 39, Issue:6

    Topics: Amphetamine; Antigen-Antibody Reactions; Barbiturates; Binding Sites, Antibody; Cocaine; Electron Spin Resonance Spectroscopy; Glucuronates; Heroin; Humans; Immunoassay; Methadone; Methods; Morphine; Muramidase; Pharmaceutical Preparations; Spectrophotometry; Substance-Related Disorders

1973
Immunological assays for drugs in biological samples.
    The American journal of medical technology, 1973, Volume: 39, Issue:6

    Topics: Amphetamine; Antibody Specificity; Antigen-Antibody Reactions; Barbiturates; Binding Sites, Antibody; Cross Reactions; Electron Spin Resonance Spectroscopy; Hemagglutination Inhibition Tests; Humans; Immunoassay; Iodine Isotopes; Methadone; Methods; Morphine; Muramidase; Pharmaceutical Preparations; Radioimmunoassay; Spectrophotometry; Substance-Related Disorders

1973
Experiences with ESR as a tool for surveying narcotic addiction.
    Annals of the New York Academy of Sciences, 1973, Dec-31, Volume: 222

    Topics: Animals; Antibodies; Antigen-Antibody Reactions; Chromatography, Thin Layer; Cocaine; Codeine; Electron Spin Resonance Spectroscopy; Evaluation Studies as Topic; Glucuronates; Heroin; Humans; Mass Screening; Methadone; Methods; Morphine; Rabbits; Saliva; Spin Labels; Substance-Related Disorders; Time Factors

1973
Morphine-like drugs inhibit the stimulation of E prostaglandins of cyclic AMP formation by rat brain homogenate.
    Nature, 1974, Mar-01, Volume: 248, Issue:5443

    Topics: Adenosine Triphosphate; Animals; Brain; Cyclic AMP; Heroin; In Vitro Techniques; Methadone; Morphinans; Morphine; Naloxone; Prostaglandin Antagonists; Rats; Tritium

1974
Effects of acute and chronic adminstration of narcotic analgesics on growth hormone and corticotrophin (ACTH) secretion in rats.
    Progress in brain research, 1973, Volume: 39

    Topics: Adrenocorticotropic Hormone; Animals; Dose-Response Relationship, Drug; Growth Hormone; Male; Methadone; Morphine; Nalorphine; Naloxone; Rats

1973
[On the inhibitory effect of kinins on isolated intestinal sections].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie und experimentelle Pathologie, 1966, Volume: 254, Issue:3

    Topics: Anesthetics, Local; Animals; Atropine; Bradykinin; Caffeine; Duodenum; Ganglionic Blockers; Guanethidine; Ileum; Jejunum; Kallidin; Meperidine; Methadone; Morphine; Phenylbutazone; Rabbits

1966
Structural requirement for antitussive activity in some novel 16-substituted derivatives of 6,14-endoethenotetrahydrothebaine.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20, Issue:12

    Topics: Analgesia; Animals; Antitussive Agents; Cats; Codeine; Cough; Guinea Pigs; Methadone; Morphinans; Morphine; Rats

1968
Screening method for detection of drugs of abuse in human urine.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Alkaloids; Amphetamine; Analgesics; Barbiturates; Chlorpheniramine; Chromatography; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonists; Hot Temperature; Humans; Indicators and Reagents; Isonipecotic Acids; Meperidine; Methadone; Methods; Morphinans; Morphine; Pentazocine; Phenacetin; Phenothiazines; Quinidine; Substance-Related Disorders; Ultraviolet Rays

1971
Liquid-solid extraction of lyophilized biological material for forensic analysis. I. Application to urine samples for detection of drugs of abuse.
    Journal of chromatography, 1971, Dec-23, Volume: 63, Issue:2

    Topics: Acetates; Antidepressive Agents; Barbiturates; Chromatography, Thin Layer; Forensic Medicine; Freeze Drying; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Meperidine; Methadone; Methods; Morphine; Substance-Related Disorders

1971
The action of choline on the superior cervical ganglion of the cat.
    European journal of pharmacology, 1972, Volume: 17, Issue:1

    Topics: Animals; Atropine; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Cats; Choline; Cocaine; Denervation; Dimethylphenylpiperazinium Iodide; Drug Synergism; Electric Stimulation; Female; Ganglia, Autonomic; Ganglionic Blockers; Ganglionic Stimulants; Hexamethonium Compounds; Male; Methadone; Morphine; Nicotine; Nictitating Membrane; Sensory Receptor Cells

1972
Effects of narcotic analgesics on contractions of the chick isolated, innervated oesophagus.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:9

    Topics: Acetylcholine; Analgesics; Animals; Chickens; Cyclazocine; Dextropropoxyphene; Electric Stimulation; Esophagus; Heroin; In Vitro Techniques; Meperidine; Methadone; Morphinans; Morphine; Muscle Contraction; Nalorphine; Pentazocine; Phenazocine; Serotonin; Tachyphylaxis; Time Factors

1972
A single-dose suppression test in morphine-dependent mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:4

    Topics: Aminopyrine; Analgesics; Animals; Behavior, Animal; Humans; Isonipecotic Acids; Levorphanol; Male; Methadone; Mice; Morphinans; Morphine; Morphine Dependence; Motor Activity; Nalorphine; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome

1974
Letter: A rapid assay of affinity for the narcotic receptor in rat brain: application to methadone analogues.
    Acta pharmacologica et toxicologica, 1974, Volume: 34, Issue:1

    Topics: Alcohols; Analgesia; Animals; Brain; Culture Media; Dextromoramide; Isomerism; Methadone; Methods; Morphine; Rats; Receptors, Drug; Synaptic Membranes

1974
The increased efficacy of narcotic antagonists induced by various narcotic analgesics.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Analgesics; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Drug Synergism; Levorphanol; Male; Methadone; Mice; Morphinans; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Reaction Time; Time Factors

1974
Methadone maintenance treatment. A report on over three years experience.
    Minnesota medicine, 1974, Volume: 57, Issue:11

    Topics: Adolescent; Adult; Aged; Community Mental Health Services; Female; Health Facilities; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Minnesota; Morphine; Substance-Related Disorders

1974
Blood and tissue concentrations of drugs associated with fatalities.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Adolescent; Adult; Age Factors; Autopsy; Barbiturates; Brain Chemistry; Bronchopneumonia; Child; Chloroquine; Dextropropoxyphene; Drug Interactions; Female; Glutethimide; Humans; Kidney; Liver; Male; Meprobamate; Methadone; Morphine; Salicylates; Sex Factors; Substance-Related Disorders

1974
Optimization of extraction and separation of narcotics from urine.
    Clinical biochemistry, 1974, Volume: 7, Issue:3

    Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors

1974
Radioimmunoassay: its application to drugs of abuse.
    Pharmacology, 1974, Volume: 11, Issue:1

    Topics: Amphetamine; Animals; Antibody Formation; Antigen-Antibody Complex; Antigen-Antibody Reactions; Barbiturates; Body Fluids; Cocaine; Dronabinol; Humans; Lysergic Acid Diethylamide; Methadone; Morphine; Pentobarbital; Radioimmunoassay; Radioisotopes; Substance-Related Disorders

1974
Transport and interaction of drugs in leukocytes.
    Biochemical pharmacology, 1974, Nov-01, Volume: 23, Issue:21

    Topics: Amines; Amphetamine; Animals; Biological Transport, Active; Codeine; Drug Interactions; Fluorides; In Vitro Techniques; Kinetics; Leukocytes; Male; Methadone; Morphine; Naloxone; Pentazocine; Rats; Temperature; Time Factors

1974
Postpartum weight alteration in hamster offspring from females injected during pregnancy with either heroin, methadone, a composite drug mixture, or mescaline.
    American journal of obstetrics and gynecology, 1974, Dec-15, Volume: 120, Issue:8

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Cricetinae; Drug Combinations; Female; Heroin; Isoproterenol; Mescaline; Methadone; Morphine; Pregnancy; Trypan Blue; Vitamin A

1974
Effect of acutely administered analgesic drugs on rat brain serotonin turnover.
    European journal of pharmacology, 1974, Volume: 29, Issue:2

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Clomipramine; Dopamine; Hydroxyindoleacetic Acid; Kinetics; Male; Meperidine; Methadone; Morphine; Naloxone; Nialamide; Norepinephrine; Pargyline; Pentazocine; Rats; Serotonin; Stimulation, Chemical; Tranylcypromine; Tryptophan

1974
Chromatographic detection of narcotic antagonists in human urine.
    Journal of chromatography, 1974, Dec-18, Volume: 101, Issue:2

    Topics: Analgesics; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Cyclazocine; Humans; Hydrogen-Ion Concentration; Methadone; Morphine; Naloxone; Narcotic Antagonists; Solvents; Temperature

1974
The effects of acutely administered analgesics on the turnover of noradrenaline and dopamine in various regions of the rat brain.
    British journal of pharmacology, 1974, Volume: 52, Issue:2

    Topics: Analgesics; Animals; Brain; Corpus Striatum; Dopamine; Hypothalamus; Male; Medulla Oblongata; Methadone; Morphine; Norepinephrine; Pentazocine; Pons; Rats; Serotonin

1974
Induction of physical dependence on morphine, codeine and meperidine in the rat by continuous infusion.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Codeine; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Injections, Intraperitoneal; Male; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorphine; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Vocalization, Animal

1974
Stereospecific binding of the potent narcotic analgesic (3H) Etorphine to rat-brain homogenate.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:7

    Topics: Acetamides; Analgesics; Animals; Azides; Binding Sites; Binding, Competitive; Brain; Ethylmaleimide; Fluorides; In Vitro Techniques; Levorphanol; Male; Mercuribenzoates; Methadone; Morphinans; Morphine; Nalorphine; Naloxone; Pentanols; Phospholipases; Pronase; Prostaglandins; Rats; Receptors, Drug; Tritium; Trypsin

1973
Modification of precipitated morphine and methadone abstinence in mice by acetylcholine antagonists.
    Nature: New biology, 1973, Oct-17, Volume: 245, Issue:146

    Topics: Acetylcholine; Animals; Atropine; Drug Combinations; Humans; Mecamylamine; Methadone; Mice; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1973
Urinalysis of 39,350 samples for drugs subject to abuse in a methadone maintenance treatment programme.
    The British journal of addiction to alcohol and other drugs, 1973, Volume: 68, Issue:4

    Topics: Barbiturates; Codeine; Humans; Mass Screening; Methadone; Morphine; Phenethylamines; Quinine; Substance-Related Disorders; United States

1973
Correlates and extent of drug abuse on a methadone maintenance program.
    The British journal of addiction to alcohol and other drugs, 1974, Volume: 69, Issue:2

    Topics: Administration, Oral; Adult; California; Heroin Dependence; Humans; Male; Methadone; Morphine; Psychotherapy; Substance-Related Disorders; Time Factors

1974
Negative direct Coombs' tests in narcotic addicts receiving maintenance doses of methadone.
    Blood, 1972, Volume: 40, Issue:6

    Topics: Antibodies, Anti-Idiotypic; Chromatography, Gas; Chromatography, Thin Layer; Coombs Test; Fluorometry; Humans; Methadone; Morphine; Quinine; Substance-Related Disorders

1972
Studies on physical dependence inducible by hours exposure of mice to morphine.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:6

    Topics: Analgesia; Animals; Behavior, Animal; Body Weight; Drug Tolerance; Humans; Infusions, Parenteral; Injections; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Pentazocine; Substance Withdrawal Syndrome; Time Factors

1972
Starch and talc emboli in drug addicts' lungs.
    Journal of clinical pathology, 1972, Volume: 25, Issue:10

    Topics: Acetaminophen; Adult; Alcohols; Amobarbital; Animals; Barbiturates; Female; Foreign-Body Reaction; Humans; Inflammation; Injections, Intravenous; Methadone; Morphine; Pentobarbital; Pulmonary Alveoli; Pulmonary Embolism; Rats; Secobarbital; Starch; Substance-Related Disorders; Talc; Time Factors

1972
Hyperimmunoglobulinemia associated with narcotic addiction. Effects of methadone maintenance treatment.
    The American journal of medicine, 1973, Volume: 54, Issue:3

    Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Protein Disorders; Female; Hepatitis; Humans; Immunodiffusion; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Liver Cirrhosis; Male; Methadone; Middle Aged; Morphine; Serum Albumin; Substance-Related Disorders

1973
Stability of certain drugs of abuse in urine specimens.
    Clinical chemistry, 1972, Volume: 18, Issue:11

    Topics: Amphetamine; Azides; Cocaine; Codeine; Drug Stability; Humans; Methadone; Morphine; Pharmaceutical Preparations; Phenobarbital; Secobarbital; Substance-Related Disorders; Temperature

1972
Effects of acutely administered analgesic drugs on rat brain 5-hydroxytryptamine turnover.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Morphine; Pargyline; Pentazocine; Probenecid; Rats; Serotonin

1972
Effects of some narcotics and antagonists on synaptosomal 3 H-norepinephrine uptake.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Jun-15, Volume: 11, Issue:12

    Topics: Animals; Brain; Codeine; In Vitro Techniques; Methadone; Morphine; Nalorphine; Naloxone; Narcotics; Nerve Endings; Nerve Tissue Proteins; Norepinephrine; Pentobarbital; Pentylenetetrazole; Protein Binding; Rabbits; Synaptic Vesicles; Synaptosomes; Thebaine

1972
The thin-layer chromatography of drugs. A laboratory experiment.
    Journal of chemical education, 1972, Volume: 49, Issue:12

    Topics: Alkaloids; Barbiturates; Chromatography, Thin Layer; Drug Combinations; Humans; Indicators and Reagents; Methadone; Methods; Morphine; Quinine; Substance-Related Disorders

1972
What's happening in hard-drug rehabilitation?
    Rehabilitation literature, 1973, Volume: 34, Issue:1

    Topics: Behavior; Heroin; Heroin Dependence; Humans; Methadone; Morphine; Narcotic Antagonists; Psychotherapy; Reinforcement, Psychology; Substance-Related Disorders; Therapeutic Community; United States

1973
Opiate receptor: demonstration in nervous tissue.
    Science (New York, N.Y.), 1973, Mar-09, Volume: 179, Issue:4077

    Topics: Analgesics; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Codeine; Colchicine; Dextromethorphan; Dextropropoxyphene; Guinea Pigs; Histamine; Intestinal Mucosa; Levallorphan; Methadone; Mice; Morphine; Nalorphine; Naloxone; Phenazocine; Phenobarbital; Rats; Receptors, Drug; Serotonin; Tritium

1973
Simple gas-liquid chromatographic method for confirming the presence of alkaloids in urine.
    Clinical chemistry, 1973, Volume: 19, Issue:3

    Topics: 1-Propanol; Chloroform; Chromatography, Gas; Cocaine; Codeine; Methadone; Methods; Morphine; Solubility

1973
Analgesics and other drugs for relief of pain.
    Postgraduate medicine, 1973, Volume: 53, Issue:6

    Topics: Analgesics; Aspirin; Azepines; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Indomethacin; Methadone; Morphine; Narcotics; Pain; Pentazocine; Pyrazoles; Salicylates; Substance-Related Disorders

1973
Acute effects of narcotic analgesics on behavioral arousal in the rat.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:6

    Topics: Analgesics; Animals; Arousal; Dose-Response Relationship, Drug; Levorphanol; Locomotion; Male; Meperidine; Methadone; Methyltyrosines; Morphine; Narcotics; Pentazocine; Rats; Time Factors

1973
Analysis for drugs of abuse: the validity of reported results in relation to performance testing.
    The International journal of the addictions, 1973, Volume: 8, Issue:1

    Topics: Amphetamine; Barbiturates; Clinical Laboratory Techniques; Evaluation Studies as Topic; False Negative Reactions; False Positive Reactions; Humans; Laboratories; Licensure; Methadone; Morphine; Narcotics; New York; Phenothiazines; Quinine; Substance-Related Disorders; Urine

1973
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2

    Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium

1973
Separation of morphine alkaloids, heroin, methadone and other drugs by ion-exchange chromatography.
    Journal of chromatography, 1973, Aug-01, Volume: 82, Issue:2

    Topics: Acetaminophen; Aspirin; Autoanalysis; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Heroin; Methadone; Methods; Morphine; Opium; Phenacetin; Solvents

1973
Agonistic properties of narcotic analgesics and antagonists on the electroencephalogram and behavior in the rat and their reversal by naloxone.
    Neuropharmacology, 1973, Volume: 12, Issue:7

    Topics: Analgesics; Animals; Behavior, Animal; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Female; Meperidine; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Sleep; Time Factors

1973
Separation and quantitation of mixtures of the most commonly abused drugs.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:1

    Topics: Amobarbital; Cannabis; Chromatography, Thin Layer; Dextroamphetamine; Ephedrine; Humans; Indicators and Reagents; Lysergic Acid Diethylamide; Methadone; Methamphetamine; Methods; Morphine; Opium; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Secobarbital; Solvents; Spectrophotometry, Ultraviolet; Substance-Related Disorders

1973
A sensitive, rapid radioimmunoassay for morphine and immunologically related substances in urine and serum.
    Clinical chemistry, 1973, Volume: 19, Issue:2

    Topics: Animals; Antibody Specificity; Chromatography, Thin Layer; Cross Reactions; Dextromethorphan; Female; Goats; Heroin Dependence; Humans; Immune Sera; Male; Methadone; Methods; Morphine; Radioimmunoassay; Tritium

1973
The effect of narcotic analgesics on the homovanillic acid content of rat nucleus caudatus.
    European journal of pharmacology, 1973, Volume: 22, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Catalepsy; Caudate Nucleus; Codeine; Cyclazocine; Homovanillic Acid; Humans; Male; Methadone; Morphine; Muscle Tonus; Narcotics; Pentazocine; Phenylacetates; Rats; Structure-Activity Relationship

1973
Some behavioral and EEG effects of a new analgesic agent (viminol) in comparison with morphine in rats.
    European journal of pharmacology, 1973, Volume: 23, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Benzyl Compounds; Butylamines; Conditioning, Operant; Dose-Response Relationship, Drug; Electroencephalography; Ethanolamines; Humans; Lethal Dose 50; Locomotion; Male; Meperidine; Meprobamate; Methadone; Morphine; Pyrroles; Rats; Substance-Related Disorders; Time Factors

1973
The effect of narcotic analgesics on the uptake of 5-hydroxytryptamine and (-)-metaraminol by blood platelets.
    British journal of pharmacology, 1973, Volume: 47, Issue:4

    Topics: Alphaprodine; Animals; Blood Platelets; Cyclazocine; Dextropropoxyphene; Humans; In Vitro Techniques; Isonipecotic Acids; Metaraminol; Methadone; Morphine; Nalorphine; Narcotics; Pentazocine; Rabbits; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tritium

1973
The effect of heroin and multiple drug abuse on the electrocardiogram.
    American heart journal, 1973, Volume: 86, Issue:5

    Topics: Adolescent; Adult; Alcoholism; Barbiturates; Bradycardia; Cocaine; Death, Sudden; Electrocardiography; Female; Heart; Heart Rate; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Quinine; Substance-Related Disorders

1973
Plasma testosterone in narcotic addiction.
    The American journal of medicine, 1973, Volume: 55, Issue:3

    Topics: Adult; Alcoholism; Aspartate Aminotransferases; Ejaculation; Heroin Dependence; Humans; Libido; Male; Methadone; Morphine; New York City; Prospective Studies; Quinine; Sexual Behavior; Testosterone; Time Factors

1973
The action of hordenine on the superior cervical ganglion of the cat.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Cats; Cocaine; Dimethylamines; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epinephrine; Female; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Male; Methadone; Morphine; Muscle Contraction; Nicotine; Nictitating Membrane; Phenethylamines; Propranolol; Receptors, Adrenergic; Receptors, Cholinergic; Time Factors

1973
Stereospecific interaction of opiate narcotics in binding of 3H-dihydromorphine to membranes of rat brain.
    Life sciences, 1973, Dec-01, Volume: 13, Issue:11

    Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Corpus Striatum; Dextromethorphan; Kinetics; Levorphanol; Male; Methadone; Morphine; Naloxone; Protein Binding; Rats; Receptors, Drug; Synaptosomes; Tritium

1973
Application of high-speed liquid chromatography to the analysis of morphine, heroin, 6-(O-acetyl)morphine and methadone.
    Journal of chromatography, 1973, Dec-05, Volume: 87, Issue:1

    Topics: Autoanalysis; Chromatography, Ion Exchange; Heroin; Mass Spectrometry; Methadone; Methods; Morphine; Spectrophotometry, Ultraviolet

1973
[Social conditions and use of drugs in a group of young addicts in Oslo].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: Administration, Oral; Adolescent; Adult; Alcoholism; Amphetamine; Cannabis; Educational Status; Family; Female; Humans; Injections, Intravenous; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Morphine; Narcotics; Norway; Opium; Phenmetrazine; Social Problems; Socioeconomic Factors; Substance-Related Disorders; Time Factors; Unemployment

1973
Interactions of narcotics and their antagonists with human serum esterase. IV. Drug-receptor interaction at the acceleratory site.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 206, Issue:1

    Topics: Alkylation; Esterases; Humans; Kinetics; Methadone; Models, Biological; Molecular Conformation; Morphinans; Morphine; Narcotic Antagonists; Narcotics; Piperidines; Receptors, Drug

1973
Effect of midbrain raphe lesion on the antinociceptive action of morphine and other analgesics in rats.
    Psychopharmacologia, 1973, Dec-20, Volume: 33, Issue:4

    Topics: Animals; Codeine; Dextropropoxyphene; Meperidine; Mesencephalon; Methadone; Morphine; Rats; Serotonin

1973
[Ionization constants of several narcotic analgesics and their pain relieving action].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:1

    Topics: Analgesics; Codeine; Dextromoramide; Dimethylamines; Diphenylacetic Acids; Ethers, Cyclic; Hydrogen-Ion Concentration; Ions; Kinetics; Levorphanol; Mathematics; Meperidine; Methadone; Morphinans; Morphine; Narcotics; Piperidines

1973
Pathology and toxicology of drug addiction: a combined approach.
    Medicine, science, and the law, 1973, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Bronchopneumonia; Female; Heroin Dependence; Humans; Kidney; Liver; Lung; Lymph Nodes; Male; Methadone; Middle Aged; Morphine; Spleen; Substance-Related Disorders; Tattooing

1973
Contemporary trends in drug abuse in London as reflected by toxicological investigation of autopsy specimens.
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1973, Jun-29, Volume: 72, Issue:4

    Topics: Adult; Amphetamine; Autopsy; Barbiturates; Blood Chemical Analysis; Chromatography, Thin Layer; Female; Forensic Medicine; Humans; Kidney; Liver; London; Lung; Male; Methadone; Morphine; Social Problems; Spectrophotometry; Spleen; Substance-Related Disorders

1973
Effects of narcotic analgesics and their antagonists on the rabbit isolated heart and its adrenergic nerves.
    British journal of pharmacology, 1973, Volume: 49, Issue:4

    Topics: Animals; Autonomic Nervous System; Drug Interactions; Electric Stimulation; Female; Fentanyl; Heart; Heart Rate; In Vitro Techniques; Levallorphan; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Perfusion; Rabbits; Secretory Rate; Sympathetic Nervous System

1973
Cellular transport of CNS drugs in leukocytes.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Acetamides; Anaerobiosis; Animals; Azides; Biological Transport, Active; Brain; Carbon Radioisotopes; Cell Membrane; Dinitrophenols; Fluorides; Gelatin; Glycolysis; In Vitro Techniques; Kinetics; Leukocytes; Male; Methadone; Morphine; Narcotic Antagonists; Ouabain; Pentazocine; Rats; Temperature; Tritium

1973
The interaction of 14C-morphine with sera from immunized rabbits and from patients addicted to heroin.
    Clinical and experimental immunology, 1973, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Animals; Antibodies; Antigen-Antibody Complex; Binding Sites, Antibody; Carbon Radioisotopes; Cattle; Dialysis; Female; Half-Life; Heroin Dependence; Humans; Kinetics; Male; Methadone; Middle Aged; Morphine; Rabbits; Radioimmunoassay

1973
Insoluble salts and salt complexes of cyclazocine and naloxone.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Analgesics; Animals; Benzoates; Biopharmaceutics; Chemical Phenomena; Chemistry; Cyclazocine; Dosage Forms; Humans; Hydrogen-Ion Concentration; Methadone; Mice; Molecular Weight; Morphine; Naloxone; Salicylates; Salts; Spectrophotometry, Ultraviolet; Substance-Related Disorders; Suspensions; Tail; Tannins; Time Factors; Zinc

1973
Characteristics of the "receptor" for narcotic analgesics in synaptic plasma membrane fraction from rat brain.
    Acta pharmacologica et toxicologica, 1973, Volume: 33, Issue:5

    Topics: Acetylcholine; Animals; Binding, Competitive; Brain Stem; Cerebral Cortex; Chloromercuribenzoates; Codeine; Dextromethorphan; Ethylmaleimide; Female; Heroin; In Vitro Techniques; Levorphanol; Methadone; Morphinans; Morphine; Nalorphine; Naloxone; Physostigmine; Rats; Receptors, Drug; Structure-Activity Relationship; Subcellular Fractions; Synaptic Membranes; Tritium

1973
Anti-nociceptive activity of some thiophthalanes with morphine-like properties.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:3

    Topics: Analgesia; Analgesics; Animals; Bridged-Ring Compounds; Depression, Chemical; Dextropropoxyphene; Dimethylamines; Electric Stimulation; Ketones; Male; Meperidine; Methadone; Mice; Morphine; Pain; Piperidines; Thiophenes

1973
Stereospecific interaction between narcotic analgesics and a synaptic plasm a membrane fraction of rat cerebral cortex.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:3

    Topics: Animals; Brain; Brain Chemistry; Cerebral Cortex; Methadone; Morphine; Rats; Receptors, Drug; Synaptic Membranes; Tritium

1973
Physiologic implications of methadone treatment.
    Proceedings. National Conference on Methadone Treatment, 1973, Volume: 2

    Topics: Adult; Alcoholism; Drug Tolerance; Electrocardiography; Female; Heroin Dependence; Hospitalization; Humans; Liver Diseases; Male; Methadone; Morphine; Morphine Dependence; Prospective Studies; Retrospective Studies; Substance Withdrawal Syndrome; United States

1973
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders

1974
Use of fluorescamine ("Fluram") to detect amphetamine in urine by thin-layer chromatography.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amphetamine; Benzofurans; Chromatography, Ion Exchange; Chromatography, Thin Layer; Drug Stability; Evaluation Studies as Topic; Fluorescence; Glutethimide; Humans; Indicators and Reagents; Methadone; Methamphetamine; Methods; Microchemistry; Morphine; Pentobarbital; Phenobarbital; Phenothiazines; Quinine; Spiro Compounds; Substance-Related Disorders; Time Factors

1974
Drug associations as a measure of habit strength for specific drugs.
    The Journal of nervous and mental disease, 1974, Volume: 158, Issue:3

    Topics: Adult; Amphetamine; Association; Barbiturates; Cannabis; Culture; Ethanol; Heroin; Heroin Dependence; Humans; Male; Methadone; Morphine; Personality Inventory; Verbal Behavior; Word Association Tests

1974
Thiazine dye antagonism of opioid lethality in mice.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3

    Topics: Animals; Codeine; Dextropropoxyphene; Drug Synergism; Hexobarbital; Lethal Dose 50; Levorphanol; Male; Meperidine; Methadone; Methylene Blue; Mice; Morphinans; Morphine; Sleep; Thiazines; Time Factors; Tolonium Chloride

1974
Evaluation of a latex agglutination-inhibition slide pregnancy test (Pregnosis).
    Obstetrics and gynecology, 1974, Volume: 43, Issue:5

    Topics: Abortion, Spontaneous; Adolescent; Adult; Antidepressive Agents; Chorionic Gonadotropin; Codeine; Contraceptives, Oral; Diagnostic Errors; False Negative Reactions; False Positive Reactions; Female; Humans; Latex Fixation Tests; Male; Methadone; Morphine; Phenothiazines; Pregnancy; Pregnancy Complications; Pregnancy Tests, Immunologic; Pregnancy, Ectopic; Proteinuria

1974
Methadone inhibition of 3H-5-hydroxytryptamine uptake by synaptosomes.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:1

    Topics: Animals; Brain; Centrifugation, Density Gradient; Cold Temperature; Dinitrophenols; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Kinetics; Male; Methadone; Monoamine Oxidase Inhibitors; Morphine; Naloxone; Ouabain; Potassium Chloride; Rabbits; Serotonin; Serotonin Antagonists; Sucrose; Synaptosomes; Tritium

1974
Evaluation of deaths from drug overdose. A clinicopathologic study.
    American journal of clinical pathology, 1974, Volume: 61, Issue:6

    Topics: Accidents; Adolescent; Adult; Aged; Barbiturates; Child; Chloroquine; Dextropropoxyphene; Female; Glutethimide; Humans; Male; Meprobamate; Methadone; Middle Aged; Morphine; Poisoning; Pulmonary Edema; Salicylates; Suicide

1974
A review of some GLD-FID derivitization techniques found useful in forensic toxicology.
    Journal of chromatographic science, 1974, Volume: 12, Issue:5

    Topics: Acetylation; Amphetamine; Bromides; Chromatography, Gas; Forensic Medicine; Formaldehyde; Glycols; Humans; Methadone; Methylation; Morphine; Oxidation-Reduction; Phenytoin; Toxicology

1974
Chemical evaluation of 'drug cocktails' in autopsy specimens.
    Journal of chromatographic science, 1974, Volume: 12, Issue:5

    Topics: Adult; Amphetamine; Autopsy; Barbiturates; Body Fluids; Forensic Medicine; Hallucinogens; Humans; Hypnotics and Sedatives; Levallorphan; Male; Meperidine; Methadone; Methaqualone; Morphinans; Morphine; Pharmaceutical Preparations; Poisoning; Substance-Related Disorders; Tissue Extracts

1974
The inhibition of the uptake of monoamines by blood platelets by phenothiazines and other drugs.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Animals; Antidepressive Agents; Atropine; Biogenic Amines; Blood Platelets; Carbon Radioisotopes; Cell Membrane; Cocaine; Depression, Chemical; Dibenzazepines; Dopamine; Hemolysis; In Vitro Techniques; Metaraminol; Methadone; Methylation; Morphine; Phenothiazines; Serotonin; Structure-Activity Relationship; Surface Tension; Tritium

1974
Determination of the presence of morphine in urine.
    Clinical biochemistry, 1974, Volume: 7, Issue:2

    Topics: Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Thin Layer; Evaluation Studies as Topic; Heroin Dependence; Humans; Methadone; Methods; Microchemistry; Morphine; Radioimmunoassay; Spectrometry, Fluorescence

1974
Binding of 2,4-dinitrophenyl compounds and other small molecules to a crystalline lambda-type Bence-Jones dimer.
    Biochemistry, 1974, Aug-27, Volume: 13, Issue:18

    Topics: Amino Acid Sequence; Amino Acids; Amyloidosis; Bence Jones Protein; Binding Sites; Caffeine; Chemical Phenomena; Chemistry; Colchicine; Dansyl Compounds; Fluorine; Humans; Immunoglobulin Fragments; Immunoglobulins; Iodine; Macromolecular Substances; Methadone; Models, Structural; Morphine; Nitrobenzenes; Phenanthrolines; Protein Binding; Protein Conformation; Uracil; Vitamin K; X-Ray Diffraction

1974
Reciprocal (push-pull) effects of morphine on single units in the ventromedian and lateral hypothalamus and influences on other nuclei: with a comment on methadone effects during withdrawal from morphine.
    Brain research, 1974, Jul-05, Volume: 74, Issue:1

    Topics: Amygdala; Animals; Cerebral Cortex; Depression, Chemical; Drug Interactions; Electrophysiology; Humans; Hypothalamus; Methadone; Morphine; Morphine Dependence; Nalorphine; Naloxone; Neurons; Rats; Substance Withdrawal Syndrome; Time Factors

1974
Methadone increases mouse brain 5-hydroxyindoleacetic acid.
    Nature, 1971, Jan-08, Volume: 229, Issue:5280

    Topics: Animals; Brain; Hydroxyindoleacetic Acid; Methadone; Mice; Morphine; Pargyline; Probenecid; Serotonin; Stimulation, Chemical

1971
Confirmed identification of biotransformed drugs of abuse in urine.
    American journal of clinical pathology, 1972, Volume: 57, Issue:1

    Topics: Amphetamine; Analgesics; Barbiturates; Biotransformation; Caffeine; Cannabis; Chromatography, Gas; Chromatography, Thin Layer; Codeine; Humans; Hydrogen-Ion Concentration; Imipramine; Indicators and Reagents; Methadone; Morphine; Nicotine; Pharmaceutical Preparations; Procaine; Skin; Spectrum Analysis; Substance-Related Disorders; Tranquilizing Agents

1972
Mini thin-layer chromatography in the detection of narcotics in urine from subjects on a methadone maintenance program.
    Journal of chromatography, 1972, Mar-01, Volume: 65, Issue:3

    Topics: Chromatography, Thin Layer; Codeine; Colorimetry; Humans; Meperidine; Methadone; Methods; Morphine; Narcotics; Substance-Related Disorders

1972
U.S. Army heroin abuse identification program in Vietnam: implications for a methadone program.
    American journal of public health, 1972, Volume: 62, Issue:6

    Topics: Chromatography, Gas; Chromatography, Thin Layer; False Positive Reactions; Heroin; Humans; Methadone; Military Medicine; Morphine; Morphine Dependence; Substance-Related Disorders; United States; Vietnam

1972
Automated fluorometric method for the determination of morphine in urine.
    Journal - Association of Official Analytical Chemists, 1972, Volume: 55, Issue:4

    Topics: Autoanalysis; Fluorometry; Humans; Methadone; Methods; Morphine

1972
Simplified multiple sample urinalysis in support of a methadone clinic.
    Journal of chromatography, 1972, Aug-23, Volume: 71, Issue:1

    Topics: Amphetamine; Barbiturates; Chromatography, Thin Layer; Humans; Methadone; Morphine; Narcotics; Substance-Related Disorders

1972
Relative degree of tolerance to morphine sulfate and methadone hydrochloride in the rat and the interaction of dexamethasone.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196, Issue:1

    Topics: Analgesia; Animals; Body Weight; Dexamethasone; Drug Synergism; Drug Tolerance; Male; Methadone; Morphine; Prednisolone; Rats; Reaction Time; Triamcinolone Acetonide

1972
Resumption of morphine self-administration by ex-addict rats: an attempt to modify tendencies to relapse.
    Journal of comparative and physiological psychology, 1972, Volume: 78, Issue:3

    Topics: Animals; Disease Models, Animal; Drinking Behavior; Humans; Male; Methadone; Morphine; Morphine Dependence; Quinine; Rats; Recurrence; Reinforcement, Psychology; Substance Withdrawal Syndrome; Taste

1972
Morphine catalepsy in the rat: relation to striatal dopamine metabolism.
    European journal of pharmacology, 1972, Volume: 19, Issue:1

    Topics: Animals; Apomorphine; Brain Chemistry; Catalepsy; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Humans; Male; Methadone; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Inbred Strains

1972
Treatment of morphine-type dependence by withdrawal methods.
    JAMA, 1972, Mar-20, Volume: 219, Issue:12

    Topics: Barbiturates; Female; Heroin; Hospitalization; Humans; Male; Meperidine; Methadone; Morphine; Pregnancy; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Tranquilizing Agents

1972
Oral methadone maintenance techniques in the management of morphine-type dependence.
    JAMA, 1972, Mar-20, Volume: 219, Issue:12

    Topics: Female; Heroin; Hospitalization; Humans; Male; Methadone; Morphine; Pregnancy; Substance-Related Disorders

1972
Human chromosomes and opiates.
    Archives of general psychiatry, 1972, Volume: 27, Issue:4

    Topics: Adult; Cells, Cultured; Chromosome Aberrations; Chromosomes; Dose-Response Relationship, Drug; Female; Heroin; Humans; In Vitro Techniques; Leukocytes; Male; Methadone; Middle Aged; Mitosis; Morphine; Morphine Dependence; Quinine; Substance-Related Disorders

1972
Modifications of the XAD-2 resin column method for the extraction of drugs of abuse from human urine.
    Journal of chromatography, 1972, Sep-20, Volume: 71, Issue:3

    Topics: Amphetamine; Carbon Isotopes; Humans; Ion Exchange Resins; Methadone; Morphine; Phenobarbital; Tritium

1972
Eosinophilia and drug abuse.
    Annals of allergy, 1972, Volume: 30, Issue:11

    Topics: Amphetamine; Barbiturates; Cannabis; Cocaine; Codeine; Eosinophilia; Heroin; Humans; Lysergic Acid Diethylamide; Male; Mescaline; Methadone; Morphine; Substance-Related Disorders

1972
Blood-brain barrier: penetration of morphine, codeine, heroin, and methadone after carotid injection.
    Science (New York, N.Y.), 1972, Dec-01, Volume: 178, Issue:4064

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Carbon Isotopes; Carotid Arteries; Codeine; Heroin; Injections, Intravenous; Mannitol; Methadone; Morphine; Rats; Time Factors; Tritium

1972
Clinical implications of urine surveillance in a methadone maintenance program.
    The International journal of the addictions, 1972, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Amphetamine; Barbiturates; Evaluation Studies as Topic; Female; Humans; Male; Methadone; Morphine; Narcotics; Outpatient Clinics, Hospital; Probability; Seasons; Substance-Related Disorders

1972
Detection of morphine by hemagglutination-inhibition.
    Journal of immunology (Baltimore, Md. : 1950), 1971, Volume: 106, Issue:6

    Topics: Absorption; Antigens; Hemagglutination Inhibition Tests; Hemagglutination Tests; Humans; Immune Sera; Methadone; Morphine; Radioimmunoassay

1971
Action of picric acid on the effects of some drugs acting on the central nervous system, with special reference to opioids.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:2

    Topics: Amphetamine; Analgesia; Analgesics; Animals; Benzimidazoles; Drug Synergism; Female; Male; Meperidine; Methadone; Mice; Microsomes, Liver; Morphine; Pentazocine; Pentylenetetrazole; Picrates; Seizures; Sleep; Sodium Salicylate

1971
An implanted reservoir of morphine solution for rapid induction of physical dependence in rats.
    British journal of pharmacology, 1971, Volume: 41, Issue:3

    Topics: Animals; Body Weight; Codeine; Cyclazocine; Defecation; Female; Humans; Injections, Subcutaneous; Methadone; Methods; Morphine; Nalorphine; Pentazocine; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1971
Detection of drugs in urine for methadone treatment programs.
    Journal of chromatography, 1971, Apr-22, Volume: 57, Issue:1

    Topics: Amphetamine; Analgesics; Barbiturates; Chromatography, Gas; Chromatography, Thin Layer; Drug and Narcotic Control; Humans; Mass Screening; Methadone; Methods; Morphine; Narcotics; Quinine; Substance-Related Disorders

1971
Development of behavioral tolerance to morphine and methadone using the schedule-controlled behavior of the pigeon.
    Psychopharmacologia, 1971, Volume: 19, Issue:1

    Topics: Animals; Appetitive Behavior; Behavior, Animal; Columbidae; Drug Tolerance; Humans; Male; Methadone; Morphine; Reinforcement Schedule; Substance Withdrawal Syndrome

1971
The biochemical pharmacology of tolerance to opioid analgesics.
    The Scientific basis of medicine annual reviews, 1971

    Topics: Animals; Brain; Dactinomycin; Drug Tolerance; Methadone; Morphine; Nalorphine; Protein Biosynthesis; Rats

1971
Gas chromatographic detection of methadone and morphine in the urine of drug addicts.
    Journal of chromatography, 1971, Aug-05, Volume: 60, Issue:1

    Topics: Chromatography, Gas; Chromatography, Thin Layer; Humans; Methadone; Morphine; Substance-Related Disorders

1971
The action of arecoline on the superior cervical ganglion of the cat.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 194, Issue:2

    Topics: Animals; Atropine; Cats; Cocaine; Dimethylphenylpiperazinium Iodide; Drug Antagonism; Female; Ganglia, Autonomic; Ganglionic Stimulants; Male; Methadone; Morphine; Nicotine; Nicotinic Acids; Nictitating Membrane; Parasympathomimetics; Piperazines; Receptors, Drug; Stimulation, Chemical; Sympathetic Nervous System

1971
Effects of narcotic analgesics and antagonists on the in vivo release of acetylcholine from the cerebral cortex of the cat.
    British journal of pharmacology, 1971, Volume: 43, Issue:1

    Topics: Acetylcholine; Analgesia; Analgesics; Animals; Bridged-Ring Compounds; Cats; Cerebral Cortex; Chlorpromazine; Codeine; Dextropropoxyphene; Female; Furans; Ketones; Levallorphan; Male; Meperidine; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenanthrenes

1971
[Pharmacotherapy of morphine addiction].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1971, Volume: 27, Issue:1

    Topics: Bridged-Ring Compounds; Humans; Methadone; Morphine; Morphine Dependence; Substance Withdrawal Syndrome

1971
Narcotics and medical practice. Medical use of morphine and morphine-like drugs and management of persons dependent on them.
    JAMA, 1971, Oct-25, Volume: 218, Issue:4

    Topics: American Medical Association; Female; Health Education; Heroin; Humans; Legislation, Drug; Methadone; Morphinans; Morphine; Morphine Dependence; Pain; Personality; Pregnancy; Pregnancy Complications; Socioeconomic Factors; Substance Withdrawal Syndrome; United States

1971
Methadone treatment of heroin addicts. Early results provide more questions than answers.
    JAMA, 1971, Dec-06, Volume: 218, Issue:10

    Topics: Follow-Up Studies; Heroin; Humans; Methadone; Morphine; Quinine; Substance-Related Disorders; Time Factors

1971
Determination of drugs in biologic specimens.
    IMS, Industrial medicine and surgery, 1970, Volume: 39, Issue:10

    Topics: Analgesics; Antidepressive Agents; Barbiturates; Body Fluids; Chromatography, Gas; Chromatography, Thin Layer; Drug and Narcotic Control; Hallucinogens; Humans; Hypnotics and Sedatives; Mass Screening; Methadone; Morphine; Pharmaceutical Preparations; Spectrophotometry; Substance-Related Disorders; Tissue Extracts; Toxicology; Tranquilizing Agents; Ultraviolet Rays

1970
Absence of major medical complications among chronic opiate addicts.
    The British journal of addiction to alcohol and other drugs, 1970, Volume: 65, Issue:2

    Topics: Age Factors; Aged; Codeine; Heroin; Humans; Injections; Male; Methadone; Middle Aged; Morphine; Opium; Patient Readmission; Phenytoin; Substance-Related Disorders; Time Factors

1970
Factors influencing the incidence of reversible lens opacities in solitary and aggregated mice.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:1

    Topics: Animals; Blepharoptosis; Body Temperature; Carbon Dioxide; Cataract; Crowding; Environment; Female; Lactates; Male; Methadone; Mice; Morphine; Movement; Physical Exertion; Social Isolation

1969
[Principles and risks of drug treatment of pain].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans; Imipramine; Levallorphan; Levorphanol; Methadone; Morphine; Pain; Phenacetin; Phenylbutazone; Pyrazoles; Salicylamides; Salicylates; Sulfonic Acids

1969
Studies of drugs given before anaesthesia. XIX. The opiates.
    British journal of anaesthesia, 1970, Volume: 42, Issue:1

    Topics: Analgesics; Diazepam; Female; Fentanyl; Heroin; Humans; Levorphanol; Male; Meperidine; Methadone; Morphine; Papaverine; Phenazocine; Preanesthetic Medication; Vomiting

1970
Drug action on tail shock-induced vocalization in mice and its relevance to analgesia.
    European journal of pharmacology, 1970, Volume: 9, Issue:2

    Topics: Analgesia; Animals; Cerebral Cortex; Chlorpromazine; Codeine; Cyclazocine; Electric Stimulation; Hydroxyzine; Levallorphan; Male; Methadone; Methotrimeprazine; Mice; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Narcotics; Pentazocine; Tail; Tranquilizing Agents; Vocalization, Animal

1970
Oxygen, carbon dioxide, and pH responses in arterial blood of dogs given analgesic, neuroleptanalgesic, and ataractic agents.
    Journal of the American Veterinary Medical Association, 1970, May-15, Volume: 156, Issue:10

    Topics: Analgesics; Animals; Arteries; Atropine; Carbon Dioxide; Dogs; Hydrogen-Ion Concentration; Meperidine; Methadone; Morphine; Narcotics; Neuroleptanalgesia; Oxygen; Pentazocine; Respiration; Respiratory Function Tests; Tranquilizing Agents

1970
The "staircase maze" and the "simple staircase" in the analysis of the psychopharmacological action of CNS depressants.
    Pharmacology, 1970, Volume: 4, Issue:3

    Topics: Analgesics; Animals; Barbiturates; Behavior, Animal; Central Nervous System; Chlorpromazine; Hydroxyzine; Hypnotics and Sedatives; Meperidine; Methadone; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Rats; Reserpine; Tranquilizing Agents

1970
Quantitative studies on the antagonism by naloxone of some narcotic and narcotic-antagonist analgesics.
    British journal of pharmacology, 1970, Volume: 39, Issue:3

    Topics: Animals; Bridged-Ring Compounds; Cyclazocine; Furans; Ketones; Levorphanol; Male; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenanthrenes; Quinones; Receptors, Drug; Spasm

1970
Studies on the receptors involved in the action of the various agents in the phenylbenzoquinone analgesic assay in mice.
    British journal of pharmacology, 1970, Volume: 39, Issue:3

    Topics: Analgesics; Animals; Aspirin; Atropine; Cyclazocine; Drug Tolerance; Levorphanol; Male; Methadone; Mice; Morphine; Nalorphine; Pentazocine; Physostigmine; Quinones; Receptors, Drug; Spasm

1970
[Deaths in drug addicts. Forensic chemical studies and toxicological considerations].
    Ugeskrift for laeger, 1970, Oct-15, Volume: 132, Issue:42

    Topics: Adolescent; Adult; Barbiturates; Blood Chemical Analysis; Central Nervous System; Denmark; Dextropropoxyphene; Drug Synergism; Forensic Medicine; Humans; Liver; Male; Methadone; Morphine; Parasympatholytics; Substance-Related Disorders; Tranquilizing Agents; Urine

1970
Antagonism of the behavioral effects of morphine and methadone by narcotic antagonists in the pigeon.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: Animals; Behavior, Animal; Chlorpromazine; Columbidae; Cyclazocine; Dextroamphetamine; Drug Synergism; Male; Methadone; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine

1970
The effects of morphine-like compounds on the light responses of the brine shrimp Artemia salina.
    Psychopharmacologia, 1970, Volume: 17, Issue:4

    Topics: Animals; Decapoda; Levorphanol; Light; Methadone; Methods; Morphinans; Morphine; Nalorphine; Pentobarbital; Time Factors

1970
Influence of morphine, methadone and methadone isomers on some effects of smooth muscle stimulants.
    Research communications in chemical pathology and pharmacology, 1970, Volume: 1, Issue:1

    Topics: Acetylcholine; Animals; Barium; Bradykinin; Capillary Permeability; Depression, Chemical; Female; Guinea Pigs; Ileum; Isomerism; Methadone; Morphine; Muscle Contraction; Muscle, Smooth; Rats; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship; Substance P; Uterus

1970
[Acute tolerance to continuous subcutaneous infusion of morphine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Sep-20, Volume: 66, Issue:5

    Topics: Analgesia; Animals; Drug Tolerance; Heart Rate; Injections, Subcutaneous; Male; Meperidine; Methadone; Mice; Morphine

1970
The necessity of elution and identification of drugs indicated by thin-layer chromatography.
    Journal of chromatography, 1971, Jan-20, Volume: 54, Issue:2

    Topics: Benzamides; Chlorpromazine; Chromatography, Thin Layer; Dextropropoxyphene; Humans; Indicators and Reagents; Methadone; Methods; Morphine; Narcotics; Nicotine; Pharmaceutical Preparations; Procaine; Quinine

1971
Pharmacology of narcotics and antagonists as related to drug abuse.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Codeine; Heroin; Humans; Levallorphan; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorphine; Narcotic Antagonists; Stereoisomerism; Substance-Related Disorders

1971
Effects of narcotic analgesics upon the locomotor activity and brain catecholamine content of the mouse.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Catecholamines; Dextroamphetamine; Drug Tolerance; Levorphanol; Locomotion; Male; Methadone; Mice; Morphinans; Morphine; Motor Activity; Narcotics; Thebaine

1971
[Method of measuring analgesic activity in the rat].
    Bollettino della Societa italiana di biologia sperimentale, 1967, Dec-15, Volume: 43, Issue:23

    Topics: Analgesics; Animals; Electric Stimulation; Methadone; Morphine; Rats

1967
[The effects of spasmolytics on the mechanical and electrical activity of isolated rat uterus].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:7

    Topics: Acetylcholine; Action Potentials; Animals; Depression, Chemical; Female; In Vitro Techniques; Meperidine; Methadone; Morphine; Muscle Contraction; Muscles; Papaverine; Rats; Scopolamine; Stimulation, Chemical; Uterus

1967
Antagonism of the analgesic effect of morphine and other drugs by p-chlorophenylalanine, a serotonin depletor.
    Psychopharmacologia, 1968, Volume: 12, Issue:4

    Topics: Analgesia; Animals; Brain; Codeine; Dextropropoxyphene; Electroshock; Male; Methadone; Morphine; Pain; Phenylalanine; Rats; Serotonin; Serotonin Antagonists

1968
The addiction cycle to narcotics in the rat and its relation to catecholamines.
    Biochemical pharmacology, 1968, Volume: 17, Issue:5

    Topics: Adrenal Glands; Animals; Body Weight; Brain; Drug Tolerance; Epinephrine; Female; Growth; Humans; Levorphanol; Methadone; Monoamine Oxidase Inhibitors; Morphine; Morphine Dependence; Norepinephrine; Organ Size; Rats; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders; Thebaine; Time Factors

1968
[On characterization of the bradykinin effect on smooth muscle].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:7

    Topics: Animals; Bradykinin; Bronchi; Codeine; Fentanyl; Guinea Pigs; Ileum; Levallorphan; Methadone; Morphine; Muscle, Smooth; Nalorphine; Piperidines; Thebaine

1968
The antidiuretic effect of narcotic analgesics in the mouse.
    Toxicology and applied pharmacology, 1968, Volume: 13, Issue:2

    Topics: Animals; Biological Assay; Diuresis; Drug Antagonism; Fentanyl; Levorphanol; Methadone; Mice; Morphine; Nalorphine; Water

1968
[Addiction treatment center at Ulleråker. 1. Drug addiction control].
    Lakartidningen, 1969, Jan-29, Volume: 66, Issue:5

    Topics: Amphetamine; Barbiturates; Dextromoramide; Female; Hospitals, Psychiatric; Humans; Male; Methadone; Morphinans; Morphine; Narcotics; Phenmetrazine; Substance-Related Disorders

1969
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
    Journal of chromatography, 1969, May-20, Volume: 41, Issue:3

    Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine

1969
The specific assay of basic drugs in urine by CM-cellulose chromatography using continuous drug-dye complex extraction as a detection system.
    Journal of chromatography, 1969, Aug-05, Volume: 43, Issue:1

    Topics: Amphetamine; Buffers; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Coloring Agents; Cyclizine; Ephedrine; Guanethidine; Guanidines; Hydrogen-Ion Concentration; Meperidine; Methadone; Morphine; Spectrophotometry; Strychnine

1969
Agonist and antagonist interactions of opioids on acetic acid-induced abdominal stretching in mice.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 169, Issue:1

    Topics: Acetates; Analgesia; Animals; Behavior, Animal; Drug Antagonism; Drug Synergism; Drug Tolerance; Male; Methadone; Mice; Morphinans; Morphine; Muscles; Nalorphine; Narcotic Antagonists; Narcotics; Pentazocine; Reserpine; Tetrabenazine

1969
The responses of the terminal bile duct to morphine and morphine-like drugs.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 149, Issue:3

    Topics: Ampulla of Vater; Animals; Bile Ducts; Cats; Cattle; Dextromoramide; Dogs; In Vitro Techniques; Levorphanol; Meperidine; Methadone; Morphine; Tachyphylaxis

1965
The analgesic effect of opiate-opiate antagonist combinations in the rat.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 149, Issue:3

    Topics: Analgesics; Animals; Levallorphan; Meperidine; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Phenazocine; Rats; Sensory Receptor Cells

1965
Release of intestinal 5-hydroxytryptamine by morphine and related agents.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Calcium; Cocaine; Dogs; Female; Guinea Pigs; Ileum; Injections, Intravenous; Intestinal Mucosa; Intestines; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Nicotine; Rats; Reserpine; Serotonin; Tachyphylaxis; Uterus

1967
Oxygen consumption in the new-born rat and the effects of maternally administered analgesics.
    British journal of pharmacology and chemotherapy, 1967, Volume: 30, Issue:3

    Topics: Analgesics; Animals; Animals, Newborn; Female; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Oxygen Consumption; Pregnancy; Rats

1967
Responses of isolated dog small intestine to analgesic agents.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Analgesics; Animals; Cyclazocine; Dogs; Gastrointestinal Motility; In Vitro Techniques; Intestinal Secretions; Intestine, Small; Methadone; Morphine; Muscle Contraction; Muscle, Smooth; Pentazocine; Serotonin

1967
Antagonistic action of tolazoline upon the analgesic effect of some morphine analogues.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 16, Issue:3

    Topics: Analgesia; Animals; Drug Antagonism; Meperidine; Methadone; Morphine; Phenazocine; Rats; Tolazoline

1967
Narcotics and medical practice. Medical use of morphine and morphine-like drugs and management of persons dependent on them.
    JAMA, 1967, Oct-16, Volume: 202, Issue:3

    Topics: Amphetamine; Barbiturates; Cannabis; Drug and Narcotic Control; Female; Heroin; Humans; Legislation, Drug; Male; Methadone; Morphine; Nalorphine; Pregnancy; Substance Withdrawal Syndrome; Substance-Related Disorders; United States

1967
New, simple method for the informative investigation of sedatives.
    Psychopharmacologia, 1967, Volume: 12, Issue:1

    Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Escape Reaction; Glutethimide; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Meprobamate; Methadone; Methods; Mice; Morphine; Nialamide; Pentobarbital; Phenobarbital; Reserpine; Tubocurarine; Urethane

1967
Inhibition of the cardiac response to sympathetic nerve stimulation by opioid peptides and its potentiation by morphine and methadone.
    European journal of pharmacology, 1984, Jul-20, Volume: 102, Issue:3-4

    Topics: Animals; beta-Endorphin; Drug Synergism; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Guinea Pigs; Heart; In Vitro Techniques; Male; Methadone; Morphine; Myocardial Contraction; Norepinephrine; Sympathetic Nervous System

1984
Involvement of endogenous opioid systems in social behavior of individually-housed mice.
    Progress in clinical and biological research, 1984, Volume: 167

    Topics: Aggression; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Humans; Male; Methadone; Mice; Mice, Inbred DBA; Morphine; Motor Activity; Naloxone; Receptors, Opioid; Social Behavior; Social Isolation

1984
Differential neuropharmacological effects of mu, kappa and sigma opioid agonists on cortical EEG power spectra in the rat. Stereospecificity and naloxone antagonism.
    Neuropharmacology, 1984, Volume: 23, Issue:10

    Topics: Animals; Cerebral Cortex; Cyclazocine; Electroencephalography; Ethylketocyclazocine; Female; Methadone; Molecular Conformation; Morphine; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma

1984
Studies on action mechanisms of morphine and 1-methadone in mice.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Animals; Brain; Drug Tolerance; In Vitro Techniques; Male; Methadone; Mice; Morphine; Nociceptors; Receptors, Opioid

1984
Behavioral activating effects of opiates and opioid peptides.
    Biological psychiatry, 1980, Volume: 15, Issue:1

    Topics: Animals; Benzimidazoles; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Exploratory Behavior; Male; Methadone; Mice; Morphine; Motor Activity; Naloxone; Narcotics; Rats

1980
[Pain-relieving agents. 2].
    Sykepleien, 1980, May-20, Volume: 67, Issue:9

    Topics: Analgesics; Analgesics, Opioid; Drug Tolerance; Humans; Meperidine; Methadone; Morphine; Morphine Derivatives; Substance-Related Disorders

1980
The effects of opiates on androgen binding in the forebrain of the rat.
    International journal of fertility, 1980, Volume: 25, Issue:1

    Topics: Animals; Autoradiography; Centrifugation, Density Gradient; Cytosol; Diencephalon; Dihydrotestosterone; Female; Hydroxyapatites; Limbic System; Luteinizing Hormone; Methadone; Morphine; Rats; Receptors, Androgen; Receptors, Estrogen; Receptors, Steroid

1980
Morphine and methadone binding to human serum proteins.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:10

    Topics: Blood Proteins; Humans; Kinetics; Methadone; Morphine; Protein Binding

1980
Comparative cardiac contractile actions of six narcotic analgesics: morphine, meperidine, pentazocine, fentanyl, methadone and l-alpha-acetylmethadol (LAAM).
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:1

    Topics: Analgesics, Opioid; Animals; Cats; Depression, Chemical; Drug Interactions; Fentanyl; Meperidine; Methadone; Methadyl Acetate; Morphine; Myocardial Contraction; Naloxone; Pentazocine; Stimulation, Chemical

1980
Occurrence of corneal opacities in rats after acute administration of l-alpha-acetylmethadol.
    Toxicology and applied pharmacology, 1980, Volume: 56, Issue:2

    Topics: Analgesics, Opioid; Animals; Cornea; Corneal Opacity; Dose-Response Relationship, Drug; Male; Methadone; Methadyl Acetate; Morphine; Pupil; Rats

1980
Pharmaceutics: choice of a strong analgesic for cancer patients.
    Cancer nursing, 1982, Volume: 5, Issue:1

    Topics: Analgesics, Opioid; Humans; Methadone; Morphine; Neoplasms; Pain, Intractable

1982
Differential analgesic cross-tolerance to morphine between lipophilic and hydrophilic narcotic agonists.
    Life sciences, 1984, Jan-02, Volume: 34, Issue:1

    Topics: Analgesics, Opioid; Animals; Blood-Brain Barrier; Dose-Response Relationship, Drug; Drug Tolerance; Etorphine; Injections, Intraventricular; Injections, Subcutaneous; Male; Methadone; Mice; Morphine; Morphine Derivatives; Narcotics; Receptors, Opioid

1984
Strong analgesics in severe pain.
    Drugs, 1984, Volume: 28, Issue:1

    Topics: Analgesics, Opioid; Chronic Disease; Cocaine; Fentanyl; Half-Life; Heroin; Humans; Injections, Intramuscular; Methadone; Morphine; Pain, Intractable; Pain, Postoperative

1984
Should regional anesthesia and pharmacological agents such as beta blockers and opiates be utilized in modulating pain response?
    The Journal of trauma, 1984, Volume: 24, Issue:9 Suppl

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alfentanil; Analgesia; Analgesics; Anesthesia, Conduction; Animals; Burns; Cyclooxygenase Inhibitors; Fentanyl; Half-Life; Humans; Methadone; Models, Chemical; Morphine; Narcotics; Nerve Block; Pain; Pain Management; Propranolol

1984
Analgesic effect of opiates in offspring of opiate-treated female rats.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:4

    Topics: Analgesics, Opioid; Animals; Female; Male; Methadone; Morphine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Reaction Time; Sex Factors

1984
Opiates and thermoregulation in mice. I. Agonists.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2

    Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone

1980
Clinical effects of parenteral narcotics in hospitalized medical patients.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Codeine; Drug Utilization; Female; Humans; Hydromorphone; Injections; Male; Methadone; Morphine; Narcotics; Opium

1980
Interaction of opiates with dopamine receptors: receptor binding and behavioral assays.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:1

    Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butaclamol; Dibenzocycloheptenes; Haloperidol; Kinetics; Male; Methadone; Morphine; Naloxone; Rats; Receptors, Dopamine; Spiperone

1982
Methadone and intravenous morphine requirements. Treatment of pain due to advanced cancer.
    New York state journal of medicine, 1983, Volume: 83, Issue:7

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Palliative Care

1983
The effects of opiate agonists on growth hormone and prolactin release in rats.
    Federation proceedings, 1980, Volume: 39, Issue:8

    Topics: Animals; Apomorphine; Enkephalins; Growth Hormone; Male; Methadone; Morphine; Naloxone; Naltrexone; Parasympathomimetics; Prolactin; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Opioid; Secretory Rate

1980
Opioid mechanisms in regulation of cerebral monoamines in vivo.
    Advances in biochemical psychopharmacology, 1980, Volume: 25

    Topics: Animals; Biogenic Amines; Brain; Dopamine; Drug Tolerance; Male; Methadone; Morphine; Rats; Receptors, Opioid; Serotonin

1980
Buprenorphrine: demonstration of physical dependence liability.
    European journal of pharmacology, 1981, Mar-26, Volume: 70, Issue:3

    Topics: Animals; Buprenorphine; Drug Tolerance; Humans; Male; Methadone; Morphinans; Morphine; Naloxone; Rats; Receptors, Opioid; Substance Withdrawal Syndrome; Substance-Related Disorders

1981
Central effects of morphine, levorphanol, (-)-methadone and the opioid-like peptides beta-endorphin and D-alanine2- methionine enkephalinamide on urine volume outflow and electrolytes.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3

    Topics: Animals; beta-Endorphin; Brain; Diuresis; Electrolytes; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Levorphanol; Male; Methadone; Morphine; Naloxone; Narcotics; Rats; Vasopressins

1981
A comparison of antinociception induced by foot shock and morphine.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1

    Topics: Animals; Cyclazocine; Electroshock; Foot; Male; Methadone; Morphine; Naloxone; Nociceptors; Pain; Pentazocine; Perception; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord; Time Factors

1983
Relationship of duration of analgesia to opioid pharmacokinetic variables.
    Brain research, 1983, Dec-19, Volume: 289, Issue:1-2

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Fentanyl; Half-Life; Male; Metabolic Clearance Rate; Methadone; Morphine; Narcotics; Nociceptors; Rats; Receptors, Opioid

1983
Differential behavioral effects induced by intrathecal microinjection of opiates: comparison of convulsive and cataleptic effects produced by morphine, methadone, and D-Ala2-methionine-enkephalinamide.
    Brain research, 1984, May-07, Volume: 299, Issue:1

    Topics: Animals; Arousal; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Enkephalin, Methionine; Evoked Potentials; Injections, Spinal; Male; Methadone; Morphine; Motor Activity; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures; Spinal Cord

1984
Cataleptic effects of opiates following intrathecal administration.
    Brain research, 1984, May-07, Volume: 299, Issue:1

    Topics: Animals; Arousal; Dose-Response Relationship, Drug; Enkephalin, Methionine; Hindlimb; Injections, Spinal; Male; Methadone; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Spinal Cord

1984
Nonspecific convulsions are induced by morphine but not D-Ala2-methionine-enkephalinamide at cortical sites.
    Brain research, 1984, May-07, Volume: 299, Issue:1

    Topics: Animals; Cerebral Cortex; Drug Tolerance; Electroencephalography; Enkephalin, Methionine; Evoked Potentials; Injections, Intraventricular; Male; Methadone; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures

1984
Effects of opioids on accuracy of a fixed-ratio discrimination in monkeys and rats.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3

    Topics: Animals; Buprenorphine; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Erythrocebus patas; Ethylketocyclazocine; Isomerism; Macaca mulatta; Male; Methadone; Morphinans; Morphine; Phenazocine; Rats

1984
Initial opiate use and treatment outcome in methadone detoxification patients.
    NIDA research monograph, 1983, Volume: 43

    Topics: Humans; Hypnotics and Sedatives; Male; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Socioeconomic Factors

1983
No evidence for a protracted change in endogenous opioid activity following chronic opiate treatment in mice: parallel recovery of cross tolerance to stress and morphine antinociception.
    Psychopharmacology, 1984, Volume: 82, Issue:4

    Topics: Animals; Drug Tolerance; Endorphins; Female; Humans; Methadone; Mice; Morphine; Nociceptors; Reaction Time; Stress, Psychological

1984
Phenomenology and theoretical basis of tolerance and dependence.
    NIDA research monograph, 1984, Volume: 54

    Topics: Adaptation, Psychological; Behavior; Chemoreceptor Cells; Drug Tolerance; Hemodynamics; Humans; Male; Methadone; Morphine; Respiration; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders

1984
Various factors which affect the rate of development of tolerance and physical dependence to abused drugs.
    NIDA research monograph, 1984, Volume: 54

    Topics: Animals; Body Weight; Drug Tolerance; Humans; Methadone; Methadyl Acetate; Morphine; Naloxone; Rats; Reaction Time; Species Specificity; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1984
Evidence of serotonin-dopamine involvement in the inhibition of d-amphetamine stereotypy and appearance of stereotyped movements found respectively after acute and long-term treatment with morphine and methadone in rats.
    Life sciences, 1981, Dec-21, Volume: 29, Issue:25

    Topics: Animals; Brain; Dextroamphetamine; Dopamine; Fenclonine; Fenfluramine; Haloperidol; Humans; Male; Methadone; Methylphenidate; Morphine; Piperazines; Rats; Serotonin; Stereotyped Behavior

1981
Feline analgesia following central administration of opioids.
    Neuropharmacology, 1984, Volume: 23, Issue:8

    Topics: Analgesia; Animals; Cats; Etorphine; Injections, Subcutaneous; Male; Methadone; Microinjections; Morphine; Narcotics; Periaqueductal Gray; Reaction Time

1984
Characterization of stress-induced potentiation of opioid effects in the rat.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3

    Topics: Analgesia; Animals; Body Temperature; Hypophysectomy; Male; Methadone; Morphine; Narcotics; Rats; Rats, Inbred Strains; Stress, Physiological

1984
Methadone induced physical dependence in the rat.
    Life sciences, 1984, Feb-13, Volume: 34, Issue:7

    Topics: Animals; Behavior, Animal; Body Weight; Escape Reaction; Humans; Male; Methadone; Morphine; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Self Stimulation; Substance-Related Disorders; Tremor

1984
Differential effects of opiate peptides and alkaloids on anterior pituitary hormone secretion.
    Neuroendocrinology, 1983, Volume: 37, Issue:4

    Topics: Adult; Alkaloids; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Antagonism; Growth Hormone; Humans; Male; Methadone; Morphine; Nalorphine; Narcotics; Pentazocine; Pituitary Hormones, Anterior; Prolactin; Thyrotropin

1983
Endocrine effects of methadone in rats; acute effects in adults.
    European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4

    Topics: Aging; Animals; Corticosterone; Dose-Response Relationship, Drug; Female; Growth Hormone; Hormones; Male; Methadone; Morphine; Naloxone; Prolactin; Rats; Rats, Inbred Strains; Sex Factors; Thyrotropin

1983
Effects of opiates on fetal behavioral activity in utero.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Animals; Blood Pressure; Female; Fetal Heart; Fetus; Heart Rate; Maternal-Fetal Exchange; Methadone; Morphine; Pregnancy; Sheep

1983
Overall evaluation of treatment modalities for heroin addiction in a toxicology unit.
    Substance and alcohol actions/misuse, 1983, Volume: 4, Issue:4

    Topics: Clonidine; Heroin Dependence; Hospital Units; Humans; Methadone; Morphine; Naloxone; Narcotics; Outcome and Process Assessment, Health Care; Patient Dropouts; Substance Withdrawal Syndrome

1983
Withdrawal tolerance and unidirectional non-cross-tolerance in narcotic pellet-implanted mice.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Drug Implants; Drug Tolerance; Etorphine; Heroin; Humans; Male; Methadone; Mice; Morphine; Narcotics; Opioid-Related Disorders; Solubility; Substance Withdrawal Syndrome

1983
Substance abuse research in monkey social groups.
    Progress in clinical and biological research, 1983, Volume: 131

    Topics: Animals; Humans; Macaca nemestrina; Macaca radiata; Male; Methadone; Methamphetamine; Morphine; Motor Activity; Pentobarbital; Sexual Behavior, Animal; Social Behavior; Substance-Related Disorders

1983
A novel form of dependency of hepatic extraction ratio of opioids in vivo upon the portal vein concentration of drug: comparison of morphine, diamorphine, fentanyl, methadone and buprenorphine in the chronically cannulated cow.
    Life sciences, 1984, May-21, Volume: 34, Issue:21

    Topics: Animals; Buprenorphine; Cattle; Female; Fentanyl; Heroin; Kinetics; Liver; Liver Circulation; Methadone; Morphinans; Morphine; Narcotics

1984
Modification of drug effects by l-alpha-acetylmethadol.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:4

    Topics: Animals; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Male; Methadone; Methadyl Acetate; Morphine; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains

1984
Comparative study of postmortem barbiturates, methadone, and morphine in vitreous humor, blood, and tissue.
    Journal of forensic sciences, 1984, Volume: 29, Issue:3

    Topics: Autopsy; Barbiturates; Blood Chemical Analysis; Humans; Methadone; Morphine; Radioimmunoassay; Tissue Distribution; Vitreous Body

1984
Annual report: biological evaluation of compounds for their dependence liability. IV. Drug testing program of the Committee on Problems of Drug, Dependence, Inc. (1980).
    NIDA research monograph, 1981, Volume: 34

    Topics: Analgesics; Animals; Benzomorphans; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Drug Evaluation; Guinea Pigs; Humans; Meperidine; Methadone; Morphinans; Morphine; National Institutes of Health (U.S.); Rats; Research Support as Topic; Spectrophotometry, Infrared; Substance-Related Disorders; United States

1981
Effects of levo-alpha-acetylmethadol (LAAM) on morphine self-administration in the rat.
    Psychopharmacology, 1981, Volume: 73, Issue:1

    Topics: Animals; Electroencephalography; Female; Methadone; Methadyl Acetate; Morphine; Rats; Self Administration; Sleep, REM

1981
Effects of selected opioid agonists and antagonists on DMT- and LSD-25-induced disruption of food-rewarded bar pressing behavior in the rat.
    Psychopharmacology, 1981, Volume: 75, Issue:3

    Topics: Animals; Conditioning, Operant; Drug Interactions; Drug Synergism; Lysergic Acid Diethylamide; Male; Methadone; Morphine; N,N-Dimethyltryptamine; Naloxone; Naltrexone; Narcotics; Rats; Reinforcement, Psychology; Tryptamines

1981
Direct relationship of brain concentration of methadone with analgesia in chronic morphine-implanted and acute naloxone-treated rats.
    NIDA research monograph, 1982, Volume: 41

    Topics: Analgesia; Animals; Brain; Methadone; Morphine; Naloxone; Rats

1982
Cimetidine potentiation of narcotic action.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Aged; Cimetidine; Drug Synergism; Guanidines; Humans; Lung Neoplasms; Male; Methadone; Morphine; Narcotics; Pain

1983
Attenuation of the behavioral effects of meperidine and normeperidine by daily administration of diazepam.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:1

    Topics: Animals; Columbidae; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Male; Meperidine; Methadone; Morphine; Pentobarbital

1983
Antitussive effect of the optical isomers of mu, kappa and sigma opiate agonists/antagonists in the cat.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Antitussive Agents; Blood Pressure; Cats; Codeine; Cyclazocine; Dextromethorphan; Female; Heart Rate; Male; Methadone; Morphine; Narcotics; Phenazocine; Stereoisomerism

1983
Behavioral effects of the optical isomers of methadone in the rat during acute and chronic administration.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:2

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Isomerism; Male; Methadone; Morphine; Motor Activity; Optical Rotation; Rats

1983
The effect of morphine, methadone, and naloxone on taurine transport in human blood platelets.
    Progress in clinical and biological research, 1983, Volume: 125

    Topics: Biological Transport, Active; Blood Platelets; Humans; Kinetics; Methadone; Morphine; Naloxone; Sodium; Spectrophotometry; Taurine

1983
[Morphine and methadone in severe cancer pain--new pharmacokinetic bases for optimal therapy].
    Pharmaceutica acta Helvetiae, 1983, Volume: 58, Issue:7

    Topics: Chronic Disease; Humans; Kinetics; Methadone; Morphine; Neoplasms; Pain

1983
Effect of morphine and morphine-like drugs on carbachol-induced fighting in cats.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:2

    Topics: Aggression; Agonistic Behavior; Animals; Carbachol; Cats; Female; Humans; Injections, Intraventricular; Male; Meperidine; Methadone; Morphine

1982
Clinical evaluation of combined treatment with methadone and psychotropic drugs in cancer patients.
    Acta anaesthesiologica Scandinavica. Supplementum, 1982, Volume: 74

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Psychotropic Drugs; Time Factors

1982
Metabolic studies with an isolated, perfused rat brain preparation.
    Israel journal of medical sciences, 1982, Volume: 18, Issue:1

    Topics: Amino Acids; Animals; Blood-Brain Barrier; Brain; Dimethyl Sulfoxide; Energy Metabolism; Ethanol; Insulin; Methadone; Morphine; Perfusion; Rats

1982
Effects of parenteral morphine and oral methadone on self-stimulation in the rat.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:1

    Topics: Administration, Oral; Animals; Electric Stimulation; Injections, Intraperitoneal; Male; Methadone; Morphine; Rats; Rats, Inbred Strains; Self Stimulation

1982
The effects of morphine on calcium-regulated phosphorylation of synaptosomal cytosolic proteins from rat striatum.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:3

    Topics: Animals; Calcium; Corpus Striatum; Cytosol; In Vitro Techniques; Levorphanol; Male; Methadone; Morphine; Naloxone; Nerve Tissue Proteins; Phosphorylation; Rats; Stereoisomerism; Synaptosomes

1982
Oral methadone for relief of chronic pain from cancer.
    The New England journal of medicine, 1982, Apr-22, Volume: 306, Issue:16

    Topics: Chronic Disease; Humans; Methadone; Morphine; Neoplasms; Pain, Intractable

1982
A comparison of morphine and methadone disposition in the maternal-fetal unit.
    American journal of obstetrics and gynecology, 1982, Jul-15, Volume: 143, Issue:6

    Topics: Animals; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Metabolic Clearance Rate; Methadone; Morphine; Placenta; Pregnancy; Protein Binding; Sheep

1982
The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia.
    Pain, 1982, Volume: 12, Issue:4

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Epidural Space; Female; Fentanyl; Lipids; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Nociceptors; Pain; Reflex; Skin; Time Factors

1982
Morphine- and methadone-tolerant mice differ in cross-tolerance to other opiates. Heterogeneity in opioid mechanisms indicated.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 320, Issue:1

    Topics: Analgesia; Animals; Body Weight; Drug Tolerance; Male; Methadone; Mice; Morphine; Narcotics; Reaction Time

1982
Motility response of rats to chronic constant-dose treatment with narcotics.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:3

    Topics: Animals; Male; Meperidine; Methadone; Morphine; Motor Activity; Narcotics; Pentazocine; Rats; Rats, Inbred Strains; Time Factors

1982
The role of calmodulin in opioid-induced changes in the phosphorylation of rat striatal synaptic membrane proteins.
    Neurochemical research, 1982, Volume: 7, Issue:9

    Topics: Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Corpus Striatum; Etorphine; Kinetics; Male; Membrane Proteins; Methadone; Morphinans; Morphine; Phosphorylation; Protein Kinases; Rats; Synaptic Membranes; Synaptosomes

1982
Tolerance to methadone lethality and microsomal enzyme induction in mice tolerant to and dependent on morphine.
    Drug and alcohol dependence, 1980, Volume: 5, Issue:1

    Topics: Animals; Body Weight; Drug Tolerance; Enzyme Induction; Humans; Inactivation, Metabolic; Lethal Dose 50; Liver; Male; Methadone; Mice; Microsomes, Liver; Morphine; Morphine Dependence; Oxidoreductases, N-Demethylating; Proadifen

1980
Narcotic abstinence in dependent rats: EEG and behavioral correlates.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:1

    Topics: Animals; Behavior, Animal; Electroencephalography; Female; Humans; Methadone; Methadyl Acetate; Morphine; Opioid-Related Disorders; Rats; Sleep, REM; Substance Withdrawal Syndrome

1980
A method for determining cumulative behavioral toxicity after chronic oral administration of l-alpha-acetylmethadol to female rats.
    Neurobehavioral toxicology, 1980,Spring, Volume: 2, Issue:1

    Topics: Administration, Oral; Animals; Behavior, Animal; Drug Tolerance; Female; Fetus; Humans; Methadone; Methadyl Acetate; Morphine; Naloxone; Rats; Substance-Related Disorders

1980
Morphine challenges in levo-alpha-acetylmethadol (LAAM) post-addict rats.
    Life sciences, 1981, Mar-30, Volume: 28, Issue:13

    Topics: Animals; Female; Humans; Methadone; Methadyl Acetate; Morphine; Rats; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders; Wakefulness

1981
Differential electroencephalographic and behavioral cross tolerance to morphine and methadone in the l-alpha-acetylmethadol (LAAM)-maintained rat.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:3

    Topics: Animals; Behavior, Animal; Drug Tolerance; Electroencephalography; Female; Humans; Methadone; Methadyl Acetate; Morphine; Opioid-Related Disorders; Rats; Rats, Inbred Strains

1982
Reducing drug use among methadone maintenance clients: contingent reinforcement for morphine-free urines.
    Addictive behaviors, 1980, Volume: 5, Issue:4

    Topics: Adult; Heroin Dependence; Humans; Male; Methadone; Morphine; Reinforcement, Psychology; Substance-Related Disorders

1980
Effects of pentazocine and nalorphine of motility in chronically morphine treated rats: a potential substitution test to detect the narcotic character of a drug.
    Neuropharmacology, 1981, Volume: 20, Issue:1

    Topics: Animals; Drug Evaluation, Preclinical; Male; Methadone; Morphine; Motor Activity; Nalorphine; Narcotics; Pentazocine; Rats; Time Factors

1981
Inhibition by morphine and morphine-like drugs of nicotine-induced emesis in cats.
    Brain research bulletin, 1981, Volume: 6, Issue:5

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Emetics; Female; Injections, Intraventricular; Male; Meperidine; Methadone; Morphine; Nicotine; Vomiting

1981
Protein concentration effects on binding of 14C-codeine, 14C-morphine, and 3H-methadone to human serum albumin.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:1

    Topics: Carbon Radioisotopes; Codeine; Humans; Methadone; Morphine; Protein Binding; Serum Albumin; Tritium

1980
Effects of morphine and methadone on the isolated perfused rat brain.
    Biochemical pharmacology, 1980, Jun-01, Volume: 29, Issue:11

    Topics: Animals; Brain; Electroencephalography; Glucose; In Vitro Techniques; Lactates; Male; Methadone; Morphine; Rats

1980
Comparative study of the electroencephalographic and behavioral effects of l-alpha-acetylmethadol (LAAM), two of its metabolites and morphine and methadone in the rat.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:2

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electrocardiography; Female; Methadone; Methadyl Acetate; Morphine; Rats

1980
Effects of drugs on behavior in rats maintained on morphine, methadone or pentobarbital.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:1

    Topics: Animals; Behavior, Animal; Dextroamphetamine; Drug Administration Schedule; Drug Interactions; Male; Methadone; Morphine; Pentobarbital; Rats

1980
From IM morphine to PO methadone.
    The Western journal of medicine, 1980, Volume: 133, Issue:6

    Topics: Adult; Heroin Dependence; Humans; Male; Methadone; Morphine; Substance Withdrawal Syndrome

1980
Dantrolene treatment of opioid-induced myoclonus.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:6

    Topics: Aged; Analgesics, Opioid; Dantrolene; Humans; Male; Methadone; Middle Aged; Morphine; Muscle Relaxants, Central; Myoclonus; Pain; Palliative Care

1995
Successful use of methadone in nociceptive cancer pain unresponsive to morphine.
    Palliative medicine, 1994, Volume: 8, Issue:2

    Topics: Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain Measurement; Pain, Intractable; Palliative Care

1994
Activation of xenobiotics into free radicals by prostaglandin-H-synthase and by rat liver microsomes.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Animals; Cocaine; Free Radicals; Histamine Release; Malondialdehyde; Mast Cells; Methadone; Microsomes, Liver; Morphine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Xenobiotics

1995
The 'glibenclamide-shift' of centrally-acting antinociceptive agents in mice.
    Brain research, 1995, Apr-24, Volume: 677, Issue:2

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Glyburide; Male; Methadone; Mice; Mice, Inbred ICR; Morphine; Potassium Channels

1995
The mu1, mu2, delta, kappa opioid receptor binding profiles of methadone stereoisomers and morphine.
    Life sciences, 1995, Volume: 56, Issue:2

    Topics: Animals; Binding, Competitive; Cattle; Methadone; Morphine; Protein Binding; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reproducibility of Results; Stereoisomerism

1995
Opioids induce while nicotine suppresses apoptosis in human lung cancer cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:10

    Topics: Apoptosis; DNA Damage; DNA, Neoplasm; Drug Synergism; Hexamethonium; Humans; Lung Neoplasms; Methadone; Morphine; Nicotine; Receptors, Cholinergic; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
[Value and limitations of substitution treatments in the care of drug addicts].
    Annales de medecine interne, 1994, Volume: 145 Suppl 3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Buprenorphine; France; HIV Infections; HIV Seropositivity; Humans; Mental Disorders; Methadone; Morphine; Paris; Substance-Related Disorders; Time Factors

1994
[How to treat a patient with AIDS and drug dependence unwilling and/or unable to withdraw? Give substitution drugs at the hospital? Should substitution be continued after discharge? Is substitution a useful adjuvant to programs designed to prevent opportu
    Annales de medecine interne, 1994, Volume: 145 Suppl 3

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Buprenorphine; Emergencies; Heroin Dependence; HIV Infections; Hospitalization; Humans; Methadone; Morphine; Outpatients; Patient Care Team; Substance-Related Disorders

1994
Disappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists.
    Pain, 1994, Volume: 59, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Child; Delayed-Action Preparations; Female; Humans; Hyperalgesia; Male; Meperidine; Methadone; Middle Aged; Morphine; Myoclonus; Narcotics; Neoplasms; Pain; Sufentanil

1994
Methadone in pain uncontrolled by morphine.
    Lancet (London, England), 1993, Nov-13, Volume: 342, Issue:8881

    Topics: Adult; Female; Humans; Methadone; Morphine; Pain

1993
[Diversified prescription of narcotics to heroin addicts. Basis, design, research plan].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1994, Aug-23, Volume: 83, Issue:34

    Topics: Clinical Trials as Topic; Cocaine; Drug Prescriptions; Female; Heroin; Humans; Male; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Pilot Projects; Program Evaluation; Research Design

1994
Deaths among drug addicts in Denmark in 1987-1991.
    Forensic science international, 1994, Aug-10, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Alcoholism; Amphetamine; Analgesics, Opioid; Barbiturates; Cannabis; Cause of Death; Denmark; Dextropropoxyphene; Female; Heroin; Humans; Male; Meperidine; Methadone; Morphine; Substance-Related Disorders; Suicide; Survival Rate

1994
Effect of morphine and methadone acute treatment on immunological activity in mice: pharmacokinetic and pharmacodynamic correlates.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:3

    Topics: Animals; Cytotoxicity, Immunologic; Immunity; Killer Cells, Natural; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Neutrophils; Respiratory Burst

1994
The effects of exercise on the oral consumption of morphine and methadone in rats.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:2

    Topics: Administration, Oral; Animals; beta-Endorphin; Body Weight; Brain Chemistry; Drinking; Male; Methadone; Morphine; Physical Exertion; Rats

1994
Simultaneous determination of drugs of abuse (opiates, cocaine and amphetamine) in human hair by GC/MS and its application to a methadone treatment program.
    Forensic science international, 1993, Volume: 63, Issue:1-3

    Topics: Adult; Amphetamine; Calibration; Cocaine; Codeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Male; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders

1993
CSF neuropeptides in cancer pain: effects of spinal opioid therapy.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:5

    Topics: Aged; Bupivacaine; Female; Humans; Injections, Epidural; Injections, Spinal; Male; Methadone; Middle Aged; Morphine; Neoplasms; Neuropeptides; Pain

1993
Macrophage functions in drugs of abuse-treated mice.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:6

    Topics: Animals; Cell Division; Cells, Cultured; Cocaine; Interleukin-1; Leukemia L1210; Macrophages, Peritoneal; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1993
Legal opioid consumption in Denmark 1981-1993.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:5

    Topics: Analgesia; Analgesics, Opioid; Buprenorphine; Denmark; Humans; Legislation, Drug; Meperidine; Methadone; Morphine

1995
Free radical mediated release of histamine from rat mast cells induced by drugs of abuse.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45 Suppl 1

    Topics: Animals; Cocaine; Cyclic N-Oxides; Dose-Response Relationship, Drug; Fluorometry; Free Radical Scavengers; Free Radicals; Glutathione; Histamine Release; Illicit Drugs; L-Lactate Dehydrogenase; Malondialdehyde; Mast Cells; Methadone; Morphine; Narcotics; Peritoneal Cavity; Pleura; Rats; Rats, Wistar; Spectrophotometry; Vitamin E

1996
Influence of plasma-protein binding on analgesic effect of methadone in rats with spontaneous withdrawal.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:3

    Topics: Analgesics, Opioid; Animals; Male; Methadone; Morphine; Narcotics; Orosomucoid; Pain Measurement; Protein Binding; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

1996
Opioid rotation in patients with cancer pain. A retrospective comparison of dose ratios between methadone, hydromorphone, and morphine.
    Cancer, 1996, Aug-15, Volume: 78, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hydromorphone; Injections, Subcutaneous; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Retrospective Studies

1996
Fatal poisonings in young drug addicts in the Nordic countries: a comparison between 1984-1985 and 1991.
    Forensic science international, 1996, Mar-05, Volume: 78, Issue:1

    Topics: Adolescent; Adult; Age Distribution; Finland; Heroin; Humans; Iceland; Methadone; Morphine; Narcotics; Scandinavian and Nordic Countries; Substance-Related Disorders

1996
Changes in opioid receptor density on murine splenocytes induced by in vivo treatment with morphine and methadone.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1

    Topics: Analgesics, Opioid; Animals; Lymphocytes; Macrophages; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Receptors, Opioid; Spleen

1996
Similar decrease in spontaneous morphine abstinence by methadone and RB 101, an inhibitor of enkephalin catabolism.
    British journal of pharmacology, 1996, Volume: 119, Issue:1

    Topics: Analgesics; Animals; Disulfides; Drug Combinations; Enkephalins; Indoles; Male; Meglumine; Methadone; Morphine; Naloxone; Phenylalanine; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Substance Withdrawal Syndrome

1996
[Initial results with withdrawal treatments of male and female participants in the diversified Janus opiate prescription project in Basel].
    Praxis, 1996, Nov-26, Volume: 85, Issue:48

    Topics: Adult; Female; Heroin; Humans; Injections, Intravenous; Male; Methadone; Morphine; Substance Abuse Treatment Centers; Substance-Related Disorders; Treatment Outcome

1996
Differential opioid agonist regulation of the mouse mu opioid receptor.
    The Journal of biological chemistry, 1997, Jan-10, Volume: 272, Issue:2

    Topics: Adenylate Cyclase Toxin; Analgesics; Animals; Buprenorphine; Colforsin; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Levorphanol; Methadone; Mice; Morphine; Pertussis Toxin; Receptors, Opioid, mu; Virulence Factors, Bordetella

1997
[Pregnancy and drug dependence].
    Wiener klinische Wochenschrift, 1996, Volume: 108, Issue:19

    Topics: Administration, Oral; Adult; Austria; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Patient Care Team; Pregnancy; Pregnancy Complications

1996
International opioid consumption.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:1 Pt 2

    Topics: Analgesics, Opioid; Denmark; Drug Utilization; Humans; Meperidine; Methadone; Morphine; Pain

1997
Pharmacologic treatment of cancer pain.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Analgesics, Opioid; Humans; Methadone; Morphine; Neoplasms; Pain; Therapeutic Equivalency

1997
Intravenous methadone for cancer pain unrelieved by morphine and hydromorphone: clinical observations.
    Pain, 1997, Volume: 70, Issue:1

    Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Humans; Hydromorphone; Injections, Intravenous; Male; Methadone; Morphine; Pain; Palliative Care; Peritoneal Neoplasms; Retreatment; Stomach Neoplasms

1997
Modulation of immunoreactive protein kinase C-alpha and beta isoforms and G proteins by acute and chronic treatments with morphine and other opiate drugs in rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:4

    Topics: Animals; Brain; Dose-Response Relationship, Drug; GTP-Binding Proteins; Immunohistochemistry; Male; Methadone; Morphine; Narcotics; Protein Kinase C; Rats; Rats, Sprague-Dawley; Time Factors

1997
[Pupillary diameter and pupillary reactions in heroin dependent patients and in patients participating in a methadone and morphine replacement program].
    Wiener medizinische Wochenschrift (1946), 1997, Volume: 147, Issue:3

    Topics: Adult; Delayed-Action Preparations; Female; Heroin Dependence; Humans; Male; Methadone; Morphine; Narcotics; Pupil Disorders; Reflex, Pupillary; Signal Processing, Computer-Assisted

1997
Discriminative stimulus effects of l-alpha-acetylmethadol (LAAM), buprenorphine and methadone in morphine-treated rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2

    Topics: Animals; Buprenorphine; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Methadone; Methadyl Acetate; Morphine; Naltrexone; Narcotic Antagonists; Narcotics

1997
Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells.
    Molecular pharmacology, 1997, Volume: 52, Issue:2

    Topics: Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Cell Line; Colforsin; Cyclic AMP; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; GTP-Binding Proteins; Humans; Methadone; Mice; Morphine; Point Mutation; Radioligand Assay; Receptors, Opioid, delta; Signal Transduction; Structure-Activity Relationship

1997
Effect of acute and chronic tramadol on [3H]-5-HT uptake in rat cortical synaptosomes.
    British journal of pharmacology, 1997, Volume: 122, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cerebral Cortex; Male; Methadone; Morphine; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin; Synaptosomes; Tramadol

1997
Atypical urinary opiate excretion pattern.
    Journal of analytical toxicology, 1997, Volume: 21, Issue:6

    Topics: Adult; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Reference Standards; Twins

1997
[Pain, anesthesia and drug addiction].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1997, Volume: 98, Issue:2

    Topics: Anesthesia; Comprehensive Health Care; Heroin; Heroin Dependence; Humans; Methadone; Morphine; Narcotics; Pain; Physician-Patient Relations; Substance Abuse Treatment Centers; Substance-Related Disorders

1997
l-alpha-Acetylmethadol, l-alpha-acetyl-N-normethadol and l-alpha-acetyl-N,N-dinormethadol: comparisons with morphine and methadone in suppression of the opioid withdrawal syndrome in the dog.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2

    Topics: Analgesics, Opioid; Animals; Dogs; Dose-Response Relationship, Drug; Methadone; Methadyl Acetate; Morphine; Opioid-Related Disorders; Substance Withdrawal Syndrome

1997
[Changes in the pattern of opioid analgesic consumption in Spain].
    Medicina clinica, 1997, Sep-13, Volume: 109, Issue:8

    Topics: Administration, Oral; Administration, Rectal; Analgesics, Opioid; Buprenorphine; Codeine; Databases as Topic; Dextropropoxyphene; Drug Prescriptions; Humans; Injections, Intravenous; Linear Models; Meperidine; Methadone; Morphine; Pentazocine; Spain; Tilidine; Tramadol

1997
Intravenous high-dose methadone administered by patient controlled analgesia and continuous infusion for the treatment of cancer pain refractory to high-dose morphine.
    Pain, 1997, Volume: 73, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Treatment Outcome

1997
Regulation of G protein-coupled receptor kinase 2 in brains of opiate-treated rats and human opiate addicts.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Adolescent; Adult; Animals; beta-Adrenergic Receptor Kinases; Brain; Cyclic AMP-Dependent Protein Kinases; Female; G-Protein-Coupled Receptor Kinase 2; Humans; Male; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1998
Use of methadone in the morphine-tolerant burned paediatric patient.
    British journal of anaesthesia, 1998, Volume: 80, Issue:1

    Topics: Analgesics, Opioid; Burns; Child; Conscious Sedation; Critical Care; Drug Tolerance; Female; Humans; Infant; Methadone; Morphine; Respiration, Artificial

1998
Dose ratio between morphine and methadone in patients with cancer pain: a retrospective study.
    Cancer, 1998, Mar-15, Volume: 82, Issue:6

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Retrospective Studies

1998
Opioid responsive central pain of cerebrovascular origin: a case report.
    Palliative medicine, 1997, Volume: 11, Issue:6

    Topics: Analgesics, Opioid; Cerebrovascular Disorders; Humans; Male; Methadone; Middle Aged; Morphine; Pain, Intractable; Palliative Care

1997
Histamine release from rat mast cells induced by the metabolic activation of drugs of abuse into free radicals.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:3

    Topics: Animals; Biotransformation; Cell Separation; Cocaine; Dopamine Uptake Inhibitors; Enzyme Induction; Free Radical Scavengers; Free Radicals; Histamine Release; Illicit Drugs; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Mast Cells; Methadone; Microsomes, Liver; Morphine; Narcotics; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar

1998
Opioid receptor agonists and antagonists alter GBR12909-induced turning in the rat.
    European journal of pharmacology, 1998, Feb-19, Volume: 343, Issue:2-3

    Topics: Animals; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Methadone; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid

1998
A method for the confirmation and identification of drugs of misuse in urine using solid phase extraction and gas-liquid chromatography with mass spectrometry.
    Journal of clinical pathology, 1998, Volume: 51, Issue:4

    Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Methadone; Morphine; Morphine Derivatives; Sensitivity and Specificity; Substance Abuse Detection

1998
Methadone analgesia in morphine-insensitive CXBK mice.
    European journal of pharmacology, 1998, Jun-19, Volume: 351, Issue:2

    Topics: Analgesia; Analgesics, Opioid; Animals; Drug Resistance; Male; Methadone; Mice; Morphine

1998
Drugs for pain.
    The Medical letter on drugs and therapeutics, 1998, Aug-14, Volume: 40, Issue:1033

    Topics: Acetaminophen; Administration, Oral; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Aspirin; Constipation; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Tolerance; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Ketorolac; Levorphanol; Meperidine; Methadone; Morphine; Narcotic Antagonists; Narcotics; Pain; Tolmetin; Tramadol

1998
Apparent thermodynamic parameters of ligand binding to the cloned rat mu-opioid receptor.
    European journal of pharmacology, 1998, Aug-07, Volume: 354, Issue:2-3

    Topics: Analgesics; Animals; Binding, Competitive; CHO Cells; Cricetinae; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Ligands; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Pentazocine; Peptide Fragments; Peptides; Radioligand Assay; Rats; Receptors, Opioid, mu; Somatostatin; Sufentanil; Thermodynamics; Time Factors

1998
Comment on Manfredi et al.,Pain, 70 (1997) 199-101.
    Pain, 1998, Volume: 77, Issue:1

    Topics: Analgesics, Opioid; Humans; Hydromorphone; Injections, Intravenous; Methadone; Morphine; Neoplasms; Palliative Care; Retreatment

1998
Effects of prolonged exposure to morphine and methadone on in vivo parameters of immune function in rats.
    Toxicology, 1998, Aug-21, Volume: 129, Issue:2-3

    Topics: Animals; Immunity; Immunoglobulins; Listeria monocytogenes; Male; Methadone; Morphine; Narcotics; Rats; Rats, Wistar; Trichinella spiralis

1998
Methadone in cancer pain management: individualize dose and titrate to effect.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:10

    Topics: Analgesics, Opioid; Humans; Methadone; Morphine; Neoplasms; Pain Management

1998
Switching from morphine to oral methadone in treating cancer pain: what is the equianalgesic dose ratio?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:10

    Topics: Administration, Oral; Aged; Analgesia; Analgesics, Opioid; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Prospective Studies; Therapeutic Equivalency; Time Factors

1998
The mu opioid irreversible antagonist beta-funaltrexamine differentiates the discriminative stimulus effects of opioids with high and low efficacy at the mu opioid receptor.
    Psychopharmacology, 1998, Volume: 140, Issue:1

    Topics: Animals; Buprenorphine; Butorphanol; Columbidae; Discrimination Learning; Female; Fentanyl; Levallorphan; Methadone; Morphine; Nalbuphine; Nalorphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu

1998
Altered plasma and brain disposition and pharmacodynamics of methadone in abstinent rats.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:1

    Topics: Analgesics, Opioid; Animals; Brain; Male; Methadone; Morphine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

1999
Opioid substitution to reduce adverse effects in cancer pain management.
    The Medical journal of Australia, 1999, Jan-18, Volume: 170, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hospice Care; Humans; Male; Medical Audit; Methadone; Middle Aged; Morphine; Nausea; Neoplasms; Oxycodone; Pain; Pain Measurement; Prospective Studies; Sleep Stages; Sufentanil; Vomiting

1999
Opioids accelerate fetal rat lung maturation in vitro.
    American journal of respiratory cell and molecular biology, 1999, Volume: 20, Issue:3

    Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Heroin; In Vitro Techniques; Lung; Methadone; Morphine; Narcotics; Rats; Rats, Sprague-Dawley

1999
Effect of electrolyte and solvent composition on capillary electrophoretic separation of some pharmaceuticals in non-aqueous media.
    Journal of biochemical and biophysical methods, 1999, Jan-29, Volume: 38, Issue:2

    Topics: Acetates; Acetonitriles; Ammonium Chloride; Bromides; Dextromoramide; Dose-Response Relationship, Drug; Electrolytes; Electrophoresis, Capillary; Ephedrine; Hydrogen-Ion Concentration; Levorphanol; Lithium Compounds; Methadone; Methanol; Morphine; Potassium Acetate; Quaternary Ammonium Compounds; Sodium Acetate; Time Factors; Viscosity

1999
Harm reduction in Bern: from outreach to heroin maintenance.
    Bulletin of the New York Academy of Medicine, 1995,Winter, Volume: 72, Issue:2

    Topics: Drug and Narcotic Control; Drug Prescriptions; Health Policy; Heroin; Humans; Methadone; Morphine; Narcotics; Substance Abuse, Intravenous; Substance-Related Disorders; Switzerland

1995
d-Methadone blocks morphine tolerance and N-methyl-D-aspartate-induced hyperalgesia.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Agonists; Hyperalgesia; Injections, Spinal; Male; Methadone; Mice; Morphine; N-Methylaspartate; Pain Measurement; Rats; Rats, Sprague-Dawley; Stereoisomerism

1999
The difference between methadone and morphine in regulation of delta-opioid receptors underlies the antagonistic effect of methadone on morphine-mediated cellular actions.
    European journal of pharmacology, 1999, Jun-04, Volume: 373, Issue:2-3

    Topics: Adenylyl Cyclases; Alkaloids; Analgesics, Opioid; Animals; Benzophenanthridines; Colforsin; Cyclic AMP; Enkephalin, Leucine-2-Alanine; Enzyme Inhibitors; Hybrid Cells; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Phenanthridines; Protein Kinase C; Rats; Receptors, Opioid, delta; Time Factors; Tumor Cells, Cultured

1999
Nalorphine's ability to substitute for morphine in a drug discrimination procedure is a function of training dose.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 63, Issue:3

    Topics: Animals; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Female; Generalization, Response; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Narcotics; Rats; Rats, Long-Evans

1999
Methadone-induced desensitization of the delta-opioid receptor is mediated by uncoupling of receptor from G protein.
    European journal of pharmacology, 1999, Jun-18, Volume: 374, Issue:2

    Topics: Animals; CHO Cells; Cricetinae; Cyclic AMP; Down-Regulation; Drug Interactions; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Methadone; Morphine; Neuroblastoma; Protein Binding; Rats; Receptors, Opioid, delta; Time Factors; Tumor Cells, Cultured

1999
Drug abuse-related mortality: a study of teenage addicts over a 20-year period.
    Social psychiatry and psychiatric epidemiology, 1999, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Age Distribution; Behavior, Addictive; England; Female; Heroin; Humans; Longitudinal Studies; Male; Methadone; Morphine; Mortality; Narcotics; Sex Distribution; Substance-Related Disorders; Suicide; Wales

1999
Rapid switching from morphine to methadone in cancer patients with poor response to morphine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:10

    Topics: Aged; Analgesics, Opioid; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Patient Satisfaction; Prospective Studies

1999
Reduction in constipation and laxative requirements following opioid rotation to methadone: a report of four cases.
    Journal of pain and symptom management, 1999, Volume: 18, Issue:4

    Topics: Analgesics, Opioid; Cathartics; Constipation; Female; Humans; Methadone; Middle Aged; Morphine

1999
The dual modulation of GIRK1/GIRK2 channels by opioid receptor ligands.
    European journal of pharmacology, 1999, Dec-03, Volume: 385, Issue:2-3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dextropropoxyphene; DNA, Recombinant; Dose-Response Relationship, Drug; Electric Stimulation; Female; GTP-Binding Proteins; Ligands; Membrane Potentials; Methadone; Mice; Microinjections; Morphine; Naloxone; Oocytes; Patch-Clamp Techniques; Plasmids; Potassium Channels; Receptors, Opioid, kappa; Receptors, Opioid, mu; RNA, Complementary; Xenopus laevis

1999
Opioid consumption in Spain--the significance of a regulatory measure.
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:9

    Topics: Analgesics, Opioid; Drug and Narcotic Control; Drug Utilization; Fentanyl; Humans; Meperidine; Methadone; Morphine; Regression Analysis; Spain; Tilidine

1999
Discriminative stimulus effects of two doses of fentanyl in rats: pharmacological selectivity and effect of training dose on agonist and antagonist effects of mu opioids.
    Psychopharmacology, 2000, Volume: 148, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Fentanyl; Male; Methadone; Morphine; Nalbuphine; Nalorphine; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu

2000
Effects of opioid receptor agonists on cAMP second messenger system.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:5

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Buprenorphine; Cyclic AMP; Etorphine; Glioma; Humans; Hybrid Cells; Methadone; Morphine; Neuroblastoma; Opioid-Related Disorders; Receptors, Opioid; Receptors, Opioid, delta; Tumor Cells, Cultured

1999
Effects of low-pH treatment on cAMP second messenger system regulated by different opioid agonists.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:6

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Buprenorphine; Cyclic AMP; Etorphine; Glioma; Humans; Hybrid Cells; Hydrogen-Ion Concentration; Methadone; Morphine; Neuroblastoma; Opioid-Related Disorders; Receptors, Opioid, delta; Tumor Cells, Cultured

1999
Morphine and methadone have different effects on calcium channel currents in neuroblastoma cells.
    Brain research, 2000, Jul-07, Volume: 870, Issue:1-2

    Topics: Animals; Calcium Channels; Membrane Potentials; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neuroblastoma; Neurons; Patch-Clamp Techniques; Tumor Cells, Cultured

2000
The merits of methadone.
    The American journal of nursing, 2000, Volume: 100, Issue:7

    Topics: Adult; Analgesics, Opioid; Child; Child, Preschool; Chronic Disease; Humans; Methadone; Morphine; Neoplasms; Pain

2000
Morphine discriminative control is mediated by the mu opioid receptor: assessment of delta opioid substitution and antagonism.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:4

    Topics: Animals; Benzamides; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Generalization, Response; Methadone; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Piperazines; Rats; Rats, Long-Evans; Receptors, Opioid, delta; Receptors, Opioid, mu

2000
Modified liquid junction interface for nonaqueous capillary electrophoresis-mass spectrometry.
    Electrophoresis, 2000, Volume: 21, Issue:15

    Topics: Codeine; Electrophoresis, Capillary; Equipment Design; Indicators and Reagents; Levorphanol; Methadone; Morphine; Pentazocine; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2000
[Fatal intoxications among drug addicts in Denmark in 1997].
    Ugeskrift for laeger, 2000, Sep-25, Volume: 162, Issue:39

    Topics: Adolescent; Adult; Analgesics, Opioid; Cause of Death; Denmark; Drug Overdose; Female; Forensic Medicine; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Substance-Related Disorders

2000
Comparison of [(3)H]Glyburide binding with opiate analgesia, tolerance, and dependence in ICR and Swiss-Webster mice.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:3

    Topics: Analgesics, Opioid; Animals; ATP-Binding Cassette Transporters; Drug Tolerance; Glyburide; Male; Methadone; Mice; Morphine; Motor Activity; Opioid-Related Disorders; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Species Specificity; Sulfonylurea Receptors; Time Factors

2000
[Opioids. Pharmacology, clinic, prospectives for an extensive use].
    Recenti progressi in medicina, 2000, Volume: 91, Issue:12

    Topics: Analgesics, Opioid; Codeine; Drug Tolerance; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Oxycodone; Receptors, Opioid; Tramadol

2000
Trends in licit opioid use in Australia, 1984-1998: comparative analysis of international and jurisdictional data.
    The Medical journal of Australia, 2000, Nov-20, Volume: 173, Issue:10

    Topics: Australia; Developed Countries; Drug Utilization; Humans; Meperidine; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Practice Patterns, Physicians'

2000
Morphine and alternative opioids in cancer pain: the EAPC recommendations.
    British journal of cancer, 2001, Mar-02, Volume: 84, Issue:5

    Topics: Administration, Oral; Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Administration Schedule; Fentanyl; Humans; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Injections, Subcutaneous; Methadone; Morphine; Neoplasms; Oxycodone; Pain; Palliative Care

2001
Agonists determine the pattern of G-protein activation in mu-opioid receptor-mediated supraspinal analgesia.
    Brain research bulletin, 2001, Jan-15, Volume: 54, Issue:2

    Topics: Analgesics, Opioid; Animals; Buprenorphine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heroin; Heterotrimeric GTP-Binding Proteins; Lateral Ventricles; Male; Methadone; Mice; Morphine; Pain Measurement; Receptors, Opioid, mu

2001
Methadone in treatment of tenesmus not responding to morphine escalation.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2001, Volume: 9, Issue:2

    Topics: Aged; Analgesics, Opioid; Anus Diseases; Defecation; Humans; Male; Methadone; Morphine; Pain; Rectal Neoplasms; Sensation Disorders

2001
Determination of opiates in serum, saliva and hair addicted persons.
    Przeglad lekarski, 2001, Volume: 58, Issue:4

    Topics: Adult; Codeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Hydrogen-Ion Concentration; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Opioid-Related Disorders; Saliva

2001
Drug related deaths in the Strathclyde region of Scotland, 1995-1998.
    Forensic science international, 2001, Oct-15, Volume: 122, Issue:1

    Topics: Adolescent; Adult; Cause of Death; Diazepam; Female; Humans; Incidence; Male; Methadone; Middle Aged; Morphine; Prisoners; Scotland; Substance-Related Disorders; Temazepam

2001
Detection of opiate use in a methadone maintenance treatment population with the CEDIA 6-acetylmorphine and CEDIA DAU opiate assays.
    Journal of analytical toxicology, 2001, Volume: 25, Issue:7

    Topics: Adolescent; Adult; Cocaine-Related Disorders; Codeine; False Positive Reactions; Female; Gas Chromatography-Mass Spectrometry; Heroin Dependence; Humans; Immunoenzyme Techniques; Male; Methadone; Middle Aged; Morphine; Morphine Derivatives; Narcotics; Sensitivity and Specificity; Substance Abuse Detection; Workplace

2001
Opioid therapy for chronic painful conditions.
    Medicine and health, Rhode Island, 2001, Volume: 84, Issue:10

    Topics: Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Fentanyl; Humans; Karnofsky Performance Status; Low Back Pain; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Pain; Patient Selection; Practice Guidelines as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Time Factors

2001
Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal.
    Neuron, 2001, Dec-06, Volume: 32, Issue:5

    Topics: Analgesics, Opioid; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Drug Tolerance; Endocytosis; Humans; Methadone; Morphine; Mutation; Narcotics; Protein Transport; Receptors, Opioid, mu; Substance Withdrawal Syndrome

2001
Methadone enhances human immunodeficiency virus infection of human immune cells.
    The Journal of infectious diseases, 2002, Jan-01, Volume: 185, Issue:1

    Topics: Adult; Drug Interactions; Fetus; HIV Infections; Humans; Immunosuppressive Agents; Macrophages; Methadone; Microglia; Middle Aged; Monocytes; Morphine; Naltrexone; Narcotics; Receptors, CCR5

2002
HIV and hepatitis virus infections among injecting drug users in a medically controlled heroin prescription programme.
    European journal of public health, 2001, Volume: 11, Issue:4

    Topics: Adult; Drug Prescriptions; Female; Health Policy; Hepatitis B; Hepatitis C; Heroin; HIV Infections; Humans; Incidence; Male; Methadone; Morphine; Prevalence; Public Health Practice; Substance Abuse, Intravenous; Switzerland

2001
Patient-controlled analgesia with intravenous L-methadone in a child with cancer pain refractory to high-dose morphine.
    Journal of pain and symptom management, 2002, Volume: 23, Issue:1

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Child; Humans; Infusions, Intravenous; Male; Methadone; Morphine; Neoplasms; Pain, Intractable; Treatment Failure

2002
Reduced tolerance to the anti-hyperalgesic effect of methadone in comparison to morphine in a rat model of mononeuropathy.
    Pain, 2002, Volume: 95, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Drug Tolerance; Hyperalgesia; Male; Methadone; Mononeuropathies; Morphine; Rats; Rats, Sprague-Dawley

2002
Neurologic complications including paralysis after a medication error involving implanted intrathecal catheters.
    The American journal of medicine, 2002, Volume: 112, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Catheters, Indwelling; Cluster Analysis; Cohort Studies; Disease Outbreaks; Drug Compounding; Drug Contamination; Epidural Abscess; Ethanol; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Medication Errors; Methadone; Methanol; Middle Aged; Morphine; Pain; Paralysis; Pharmacy; Risk Factors; Tennessee

2002
Slow metabolism and long half life of methadone in a patient with lung cancer and cirrhosis.
    Annales de medecine interne, 2001, Volume: 152 Suppl 7

    Topics: Adenocarcinoma; Adult; Analgesics, Opioid; Fibrosis; Half-Life; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Methadone; Morphine; Opioid-Related Disorders; Pain

2001
[Opioid treatment of pain in angina pectoris].
    Ugeskrift for laeger, 2002, Apr-22, Volume: 164, Issue:17

    Topics: Aged; Analgesics, Opioid; Angina, Unstable; Humans; Male; Methadone; Morphine; Substance Withdrawal Syndrome

2002
Differential antinociception by morphine and methadone in two sub-strains of Sprague-Dawley rats and its potentiation by dextromethorphan.
    Brain research, 2002, Jun-28, Volume: 942, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Catalepsy; Central Nervous System; Dextromethorphan; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Methadone; Morphine; Neurons; Nociceptors; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid

2002
Successful use of oral methadone after failure of intravenous morphine and ketamine.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:4

    Topics: Acute Disease; Administration, Oral; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Drug Tolerance; Humans; Ketamine; Male; Methadone; Morphine; Opioid-Related Disorders; Pain; Substance Abuse, Intravenous

2002
Synergy between mu opioid ligands: evidence for functional interactions among mu opioid receptor subtypes.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:2

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Gastrointestinal Transit; Ligands; Male; Methadone; Mice; Morphine; Pain Measurement; Receptors, Opioid, mu

2002
Methadone, morphine and PTSD.
    The Australian and New Zealand journal of psychiatry, 2002, Volume: 36, Issue:6

    Topics: Adult; Analgesics, Opioid; Female; Humans; Methadone; Morphine; Stress Disorders, Post-Traumatic; Substance-Related Disorders

2002
Flunitrazepam variably alters morphine, buprenorphine, and methadone lethality in the rat.
    Human & experimental toxicology, 2002, Volume: 21, Issue:11

    Topics: Animals; Anti-Anxiety Agents; Buprenorphine; Drug Interactions; Flunitrazepam; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Male; Methadone; Morphine; Narcotics; Rats; Rats, Sprague-Dawley

2002
[Clinial study of "qingjunyin" detoxification for the treatment of heroin addicts].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 1997, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Clonidine; Drug Combinations; Drug Evaluation; Drugs, Chinese Herbal; Female; Heroin Dependence; Humans; Male; Methadone; Morphine; Phytotherapy

1997
Discrimination of a single dose of morphine followed by naltrexone: substitution of other agonists for morphine and other antagonists for naltrexone in a rat model of acute dependence.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:3

    Topics: Acute Disease; Analgesics, Opioid; Animals; Disease Models, Animal; Fentanyl; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders

2003
Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Electric Conductivity; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Methadone; Mice; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Neuroblastoma; Pentazocine; Pituitary Neoplasms; Receptors, Opioid, mu; Transfection; Tumor Cells, Cultured

2003
Use of irreversible antagonists to determine the relative efficacy of mu-opioids in a pigeon drug discrimination procedure: comparison of beta-funaltrexamine and clocinnamox.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:3

    Topics: Animals; Cinnamates; Columbidae; Female; Fentanyl; Methadone; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Narcotics; Reaction Time; Receptors, Opioid, mu; Sufentanil

2003
Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial.
    Neurology, 2003, Mar-25, Volume: 60, Issue:6

    Topics: Analgesics, Opioid; Herpes Zoster; Humans; Methadone; Morphine; Neuralgia; Neurotransmitter Uptake Inhibitors; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Reproducibility of Results

2003
[Electrodermal activity in heroin addicts and patients with methadone and morphine substitution].
    Wiener medizinische Wochenschrift (1946), 2003, Volume: 153, Issue:3-4

    Topics: Adult; Arousal; Austria; Delayed-Action Preparations; Female; Galvanic Skin Response; Habituation, Psychophysiologic; Heroin Dependence; Humans; Male; Methadone; Morphine; Reaction Time; Reference Values; Rehabilitation Centers; Sympathetic Nervous System

2003
Opioid plasma concentration during switching from morphine to methadone: preliminary data.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2003, Volume: 11, Issue:5

    Topics: Administration, Oral; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Prospective Studies; Time Factors; Treatment Outcome

2003
An ad libitum schedule for conversion of morphine to methadone in advanced cancer patients: an open uncontrolled prospective study in a Chinese population.
    Palliative medicine, 2003, Volume: 17, Issue:2

    Topics: Administration, Oral; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; China; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Prospective Studies

2003
Methadone and its role in drug-related fatalities in Cologne 1989-2000.
    Forensic science international, 2003, Apr-08, Volume: 132, Issue:3

    Topics: Benzodiazepines; Cause of Death; Drug Overdose; Ethanol; Female; Germany; Heroin; Humans; Illicit Drugs; Male; Methadone; Morphine; Narcotics; Substance-Related Disorders

2003
Strabismus in infants of opiate-dependent mothers.
    Acta paediatrica (Oslo, Norway : 1992), 2003, Volume: 92, Issue:3

    Topics: Australia; Codeine; Cross-Sectional Studies; Female; Heroin; Humans; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Neonatal Screening; Opioid-Related Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Severity of Illness Index; Strabismus

2003
Methadone substitution: medicolegal problems in Germany.
    Forensic science international, 2003, Apr-23, Volume: 133, Issue:1-2

    Topics: Adolescent; Adult; Amphetamines; Antidepressive Agents; Automobile Driving; Benzodiazepines; Cannabinoids; Cocaine; Drug and Narcotic Control; Ethanol; Female; Forensic Medicine; Germany; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Practice Patterns, Physicians'; Substance-Related Disorders

2003
Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, May-15, Volume: 23, Issue:10

    Topics: Animals; Dendrites; Endocytosis; Genetic Vectors; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Membrane Proteins; Methadone; Morphine; Mutation; Neurons; Nucleus Accumbens; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Proteins; Simplexvirus

2003
Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jun-15, Volume: 23, Issue:12

    Topics: Animals; Area Under Curve; Behavior, Animal; Cell Membrane; Dose-Response Relationship, Drug; Drug Administration Schedule; Etorphine; Female; Fentanyl; Male; Methadone; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Narcotics; Pain Measurement; Posterior Horn Cells; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Time; Up-Regulation

2003
Psychoactive drugs and quality of life.
    TheScientificWorldJournal, 2003, Aug-18, Volume: 3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphetamines; Cocaine; Cohort Studies; Data Collection; Hallucinogens; Heroin; Humans; Marijuana Abuse; Methadone; Middle Aged; Morphine; Psychotropic Drugs; Quality of Life; Stimulants, Historical; Substance-Related Disorders; Surveys and Questionnaires

2003
Action of analgesic drugs morphine, meperidine, methadone on rotatory nystagmus in the rabbit.
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 107, Issue:2

    Topics: Analgesics; Animals; Meperidine; Methadone; Morphine; Nystagmus, Pathologic; Rabbits

1953
[Microscopical detection of morphine-like compounds].
    Arzneimittel-Forschung, 1953, Volume: 3, Issue:1

    Topics: Analgesics; Meperidine; Methadone; Morphine

1953
Analgesics and enzymes of the cytochrome chain.
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 108, Issue:3

    Topics: Analgesics; Brain; Cytochromes; Meperidine; Methadone; Morphine; Myocardium; Oxidoreductases

1953
[Experiences with polamidon C].
    Die Medizinische, 1953, May-02, Volume: 21, Issue:18

    Topics: Methadone; Morphine

1953
N-Allylnormorphine: effects of single doses and precipitation of acute abstinence syndromes during addiction to morphine; methadone or heroin in man (post addicts).
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 109, Issue:1

    Topics: Behavior, Addictive; Heroin; Humans; Male; Methadone; Morphine; Nalorphine; Substance-Related Disorders; Syndrome

1953
Effects of hydergine (CCK No. 179) on the modification of tolerance to morphine and l-isomethadone hyperglycemia in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 109, Issue:2

    Topics: Animals; Drug Tolerance; Ergoloid Mesylates; Ergot Alkaloids; Hyperglycemia; Methadone; Morphine; Rabbits

1953
[Effect of drugs on the metabolism of pyruvate in fetuses and young animals. II. Morphine and synthetic morphine simulants].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:4

    Topics: Animals; Central Nervous System; Fetus; Liver; Meperidine; Methadone; Morphine; Pyruvates; Pyruvic Acid

1953
The depression of respiration by the opiates and its antagonism by nalorphine.
    Proceedings of the Royal Society of Medicine, 1953, Volume: 46, Issue:11

    Topics: Analgesics, Opioid; Depression; Depressive Disorder; Humans; Meperidine; Methadone; Morphine; Nalorphine; Respiration

1953
RAPID diagnosis of addiction to morphine.
    Journal of the American Medical Association, 1954, Jan-30, Volume: 154, Issue:5

    Topics: Behavior, Addictive; Methadone; Morphine; Morphine Dependence; Nalorphine; Substance-Related Disorders

1954
Lower limb reflexes of a "chronic spinal" man in cycles of morphine and methadone addition.
    A.M.A. archives of neurology and psychiatry, 1954, Volume: 71, Issue:2

    Topics: Behavior, Addictive; Humans; Lower Extremity; Male; Methadone; Morphine; Morphine Dependence; Reflex; Substance-Related Disorders

1954
[The effect of morphine, pethidine and methadon on peristaltic activity of intestines].
    Acta medica Iugoslavica, 1954, Volume: 8, Issue:2

    Topics: Intestines; Meperidine; Methadone; Morphine; Peristalsis

1954
Effect of adrenaline on the analgesic response of mice to morphine and related drugs.
    Archives internationales de pharmacodynamie et de therapie, 1955, Nov-01, Volume: 104, Issue:1

    Topics: Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Animals; Epinephrine; Meperidine; Methadone; Mice; Morphine; Pain Management

1955
Synthetic substances with morphine-like effect; relationship between chemical structure and analgesic action.
    Bulletin of the World Health Organization, 1955, Volume: 13, Issue:6

    Topics: Analgesics; Methadone; Morphine

1955
The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum.
    British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:1

    Topics: Acetylcholine; Codeine; Drug Tolerance; Guinea Pigs; Heroin; Ileum; Intestines; Meperidine; Methadone; Morphine; Nalorphine

1957
[Action of various synthetic analgesics in comparison with morphine & its derivatives].
    Pharmazeutische Zentralhalle fur Deutschland, 1957, Volume: 96, Issue:4

    Topics: Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Ephedrine; Meperidine; Methadone; Morphine; Pain Management

1957
[Effects of polamidone on stimulation of the respiration center, as compared with morphine].
    Therapie der Gegenwart, 1957, Volume: 96, Issue:4

    Topics: Cell Respiration; Humans; Methadone; Morphine; Respiration

1957
[Comparative analgesic effects of promedol, phenadone, tecodine, and morphine].
    Farmakologiia i toksikologiia, 1956, Volume: 19, Issue:Suppl

    Topics: Analgesics; Humans; Methadone; Morphine; Promedol

1956
A new series of potent analgesics: dextro 2:2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine and related basic amides. II. Comparative analgesic activity, acute toxicity and tolerance development in rats for R875, morphine, pethidine and methadone.
    The Journal of pharmacy and pharmacology, 1958, Volume: 10, Issue:1

    Topics: Amides; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Biphenyl Compounds; Drug Tolerance; Meperidine; Methadone; Morphine; Rats

1958
A study of the selective antagonism by N-allylnormorphine against meperidine, methadone, and morphine.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1958, Volume: 47, Issue:5

    Topics: Meperidine; Methadone; Morphine; Nalorphine

1958
[Nil nocere; Hazards of medical treatment of accident injuries caused by alcohol (with barbiturates, morphine and polamidone)].
    Munchener medizinische Wochenschrift (1950), 1958, Dec-05, Volume: 100, Issue:49

    Topics: Accidents; Barbiturates; Ethanol; Humans; Methadone; Morphine

1958
Comparative effects of analgesics on pain threshold, respiratory frequency and gastrointestinal propulsion.
    British journal of pharmacology and chemotherapy, 1959, Volume: 14, Issue:1

    Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antipyretics; Cell Respiration; Codeine; Dextromoramide; Gastrointestinal Tract; Guinea Pigs; Meperidine; Methadone; Morphine; Nalorphine; Pain; Pain Threshold; Rats; Respiration; Respiratory Rate

1959
Effect of ephedrine on morphine and methadone hyperglycaemia.
    The Indian journal of medical research, 1959, Volume: 47, Issue:2

    Topics: Ephedrine; Hyperglycemia; Methadone; Morphine

1959
[Semiquantitative determination of physical dependence in morphine and methadon therapy].
    Archiv fur Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift fur die gesamte Neurologie und Psychiatrie, 1959, Volume: 199, Issue:1

    Topics: Depression; Depressive Disorder; Humans; Methadone; Morphine; Morphine Dependence; Substance-Related Disorders

1959
Multiple toe-pinch method for testing analgesic drugs.
    British journal of pharmacology and chemotherapy, 1961, Volume: 17

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Chlorpromazine; Codeine; Guinea Pigs; Humans; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Morphine; Nalorphine; Phencyclidine; Phthalic Acids; Rats; Toes

1961
[The antagonism of "Lethidron" (N-alyl-morphine) against morphine and methadone in intraduodenal application].
    Archivos de medicina experimental; trabajos del Instituto Nacional de Ciencias Medicas, 1960, Volume: 23

    Topics: Methadone; Morphine; Nalorphine

1960
[The effect of various pharmacological agents (amphetamine, cocaine, caffeine, hexobarbital, meprobamate, morphine, dextromoramide, 1-methadone, pethidine and CT 3570) on the time of exhaustion and behavior of animals swimming at 20 degrees C].
    Medicina experimentalis : International journal of experimental medicine, 1960, Volume: 2

    Topics: Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior; Caffeine; Central Nervous System Stimulants; Cocaine; Dextromoramide; Hexobarbital; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed

1960
[Lorfan, a new morphine antagonist in poisonings in children].
    Kinderarztliche Praxis, 1960, Volume: 28

    Topics: Child; Humans; Infant; Levallorphan; Methadone; Morphine; Musculoskeletal Physiological Phenomena; Poisoning

1960
Cross-cellular adaptation to methadone and meperidine in cerebral cortical slices from morphinized rats.
    The Journal of pharmacology and experimental therapeutics, 1962, Volume: 135

    Topics: Animals; Cerebral Cortex; Meperidine; Methadone; Morphine; Rats

1962
Management of the narcotic withdrawal syndrome in the neonate.
    Pediatric clinics of North America, 1963, Volume: 10

    Topics: Barbiturates; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methadone; Morphine; Narcotics; Pregnancy; Substance Withdrawal Syndrome; Substance-Related Disorders; Tranquilizing Agents

1963
[Behavior modifiers inthe study of bile ducts. (Combined action of morphine substances and cholecystokinin)].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1963, Volume: 44

    Topics: Ampulla of Vater; Bile Ducts; Cholecystokinin; Codeine; Dextromoramide; Hydromorphone; Meperidine; Methadone; Morphine; Opium

1963
The biological disposition of morphine and its surrogates.
    Bulletin of the World Health Organization, 1962, Volume: 27

    Topics: Codeine; Heroin; Humans; Methadone; Morphine; Nalorphine; Narcotic Antagonists

1962
GANGLIONIC ACTIONS OF MUSCARINIC SUBSTANCES.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 141

    Topics: Animals; Atropine; Autonomic Nervous System; Cats; Cholinergic Agents; Cocaine; Ganglia; Ganglia, Autonomic; Ganglionic Blockers; Hexamethonium Compounds; Methadone; Morphine; Nicotine; Nictitating Membrane; Parasympathomimetics; Pharmacology; Research

1963
[THE INHIBITION OF MORPHINE, LEVORPHAN, METHADONE AND PETHIDINE ANALGESIA IN MICE BY "SPECIFIC" AND "NONSPECIFIC" ANTAGONISTS].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1963, Nov-08, Volume: 246

    Topics: Analgesia; Animals; Atropine; Levorphanol; Meperidine; Mephenesin; Meprobamate; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain Management; Peptides; Phenobarbital; Research; Reserpine; Tissue Extracts

1963
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jan-01, Volume: 147

    Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology

1964
ELEVATION OF PLASMA HISTAMINE LEVELS IN THE DOG FOLLOWING ADMINISTRATION OF MUSCLE RELAXANTS, OPIATES AND MACROMOLECULAR POLYMERS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 143

    Topics: Acacia; Analgesics, Opioid; Blood Chemical Analysis; Codeine; Dextrans; Diatrizoate; Dogs; Histamine; Meperidine; Mesylates; Methadone; Morphine; Muscle Relaxants, Central; Niacin; Nicotinic Acids; Pharmacology; Povidone; Research; Starch; Succinylcholine; Tubocurarine

1964
ANALGESICS FOR THE RELIEF OF PAIN. I. NARCOTIC ANALGESICS.
    Wisconsin medical journal, 1964, Volume: 63

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pain; Phenazocine; Piperidines

1964
USE OF DRUGS IN THE TREATMENT OF RHEUMATOID ARTHRITIS.
    Physiotherapy, 1964, Volume: 50

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Codeine; Humans; Hydroxychloroquine; Methadone; Morphine; Oxyphenbutazone; Phenylbutazone; Toxicology

1964
[RE-ANESTHESIA].
    Der Anaesthesist, 1964, Volume: 13

    Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, General; Anesthesiology; Atropa belladonna; Atropine; Barbiturates; Chlorpromazine; Dihydroergotoxine; Ergot Alkaloids; Humans; Meperidine; Methadone; Morphine; Procainamide; Promazine; Promethazine; Reserpine; Scopolamine

1964
STATISTICS AS APPLIED TO PHARMACOLOGICAL AND TOXICOLOGICAL SCREENING.
    Progress in medicinal chemistry, 1963, Volume: 19

    Topics: Arsphenamine; Atropine; Biological Assay; Biometry; Cocaine; Digoxin; Epinephrine; Ergonovine; Ergot Alkaloids; Hexamethonium Compounds; Histamine; Insulin; Meperidine; Methadone; Morphine; Pharmacology; Promethazine; Research; Riboflavin; Statistics as Topic; Strophanthins; Toxicology; Tubocurarine

1963
STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS. I. ABSOLUTE CONFIGURATION OF CERTAIN ANALGESIC (-)-N-(2-(PHENALKYLMETHYLAMINO)PROPYL)PROPIONANILIDES.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Meperidine; Methadone; Morphine; Pharmacology; Pharmacy; Research

1964
QUANTITATIVE STUDIES OF THE ANTAGONISM BY NALORPHINE OF SOME OF THE ACTIONS OF MORPHINE-LIKE ANALGESIC DRUGS.
    British journal of pharmacology and chemotherapy, 1964, Volume: 22

    Topics: Analgesics; Animals; Body Temperature; Dextromoramide; Lens, Crystalline; Levorphanol; Meperidine; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pharmacology; Research; Skin

1964
A RAPID SCREENING TEST FOR POTENTIAL ADDICTION LIABILITY OF NEW ANALGESIC AGENTS.
    Toxicology and applied pharmacology, 1964, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior, Addictive; Codeine; Dextropropoxyphene; Heroin; Hydromorphone; Meperidine; Methadone; Mice; Morphine; Phenazocine; Research; Substance-Related Disorders; Toxicology

1964
THE ACTION OF MORPHINE-LIKE DRUGS ON IMPULSE TRANSMISSION IN MAMMALIAN NERVE FIBRES.
    British journal of pharmacology and chemotherapy, 1964, Volume: 22

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Cats; Conditioning, Psychological; Hypogastric Plexus; Lagomorpha; Mammals; Meperidine; Methadone; Morphine; Nalorphine; Nerve Fibers; Neural Conduction; Nictitating Membrane; Pharmacology; Rabbits; Research; Sympathetic Nervous System

1964
THE IMPORTANCE OF STERIC CONFIGUA. ION IN CERTAIN MORPHINNE-MIMETIC ACTIONS OF SYNTHETIC ANALGETICS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 145

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Apnea; Chemical Phenomena; Chemistry; Methadone; Mice; Morphine; Nalorphine; Pain; Pharmacology; Proadifen; Research; Seizures; Toxicology

1964
THE INHIBITION OF AUTONOMIC NEURO-EFFECTOR TRANSMISSION BY MORPHINE-LIKE DRUGS AND ITS USE AS A SCREENING TEST FOR NARCOTIC ANALGESIC DRUGS .
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1964, May-25, Volume: 248

    Topics: Alkaloids; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Autonomic Agents; Cats; Guinea Pigs; Levallorphan; Levorphanol; Methadone; Morphine; Narcotics; Neuromuscular Junction; Nictitating Membrane; Opium; Pharmacology; Phenothiazines; Research

1964
GAS CHROMATOGRAPHY OF HIGH-BOILING AMINES. II. DETERMINATION OF AMINES IN LOW CONCENTRATION.
    Acta pharmaceutica Suecica, 1964, Volume: 1

    Topics: Amines; Chemistry, Pharmaceutical; Chromatography; Chromatography, Gas; Cocaine; Codeine; Ephedrine; Lidocaine; Methadone; Morphine; Pharmacy; Promazine; Research; Scopolamine

1964
[CONTROLLABLE APNEA IN ANESTHESIA BY MEANS OF CENTRAL DEPRESSION DUE TO ANALGESICS].
    Gazzetta internazionale di medicina e chirurgia, 1964, Nov-30, Volume: 68

    Topics: Analgesics; Anesthesia; Apnea; Central Nervous System Agents; Depression; Dextromoramide; Humans; Meperidine; Methadone; Morphine; Nalorphine

1964
FLUOROMETRIC IDENTIFICATION OF SUB-MICROGRAM AMOUNTS OF MORPHINE AND RELATED COMPOUNDS ON THIN-LAYER CHROMATOGRAPHS.
    Journal of chromatography, 1964, Volume: 16

    Topics: Chemistry, Pharmaceutical; Chromatography; Fluorescence; Fluorometry; Meperidine; Methadone; Morphine; Nalorphine; Research

1964
CARDIOVASCULAR ACTIONS OF NARCOTIC ANALGESICS.
    American heart journal, 1965, Volume: 69

    Topics: Cardiovascular Diseases; Drug Therapy; Humans; Meperidine; Methadone; Morphine; Narcotics; Pharmacology; Toxicology

1965
RELATIVE POTENCY OF CODEINE, METHADONE AND DIHYDROMORPHINONE TO MORPHINE IN SELF-MAINTAINED ADDICT RATS.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Jan-08, Volume: 249

    Topics: Codeine; Hydromorphone; Methadone; Morphine; Morphine Dependence; Periodicity; Pharmacology; Rats; Research

1965
A METHOD FOR THE THIN-LAYER CHROMATOGRAPHY OF ANALGESIC DRUGS AND RELATED COMPOUNDS IN NON-AQUEOUS SYSTEMS.
    Journal of chromatography, 1965, Volume: 17

    Topics: Ammonia; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Azepines; Chromatography; Chromatography, Thin Layer; Cocaine; Codeine; Dextropropoxyphene; Isonipecotic Acids; Meperidine; Methadone; Morphine; Research

1965
EFFECT OF CENTRAL DEPRESSANT AGENTS ON CEREBRAL GLUCOSE 6-PHOSPHATE DEHYDROGENASE ACTIVITY OF RATS.
    Journal of neurochemistry, 1965, Volume: 12

    Topics: Adrenal Glands; Brain; Chloroform; Erythrocytes; Ethanol; Glucose; Glucosephosphate Dehydrogenase; Kidney; Liver; Meperidine; Methadone; Morphine; NADP; Nalorphine; Pentobarbital; Pharmacology; Phosphates; Rats; Research; Spleen; Sulfhydryl Compounds

1965
[ON THE MORPHINE-LIKE PROPERTIES OF A NEW ANTITUSSIVE (ISOAMINIL; PERACON, MULLATUSS)].
    Die Pharmazie, 1964, Volume: 19

    Topics: Acetonitriles; Antitussive Agents; Codeine; Cyanides; Electron Transport Complex IV; Methadone; Mice; Morphine; Nalorphine; Pharmacology; Rats; Research; Respiration; Toxicology

1964
Rat tissue levels of carbon-14 labeled analgetics as related to pharmacological activity.
    The Journal of pharmacology and experimental therapeutics, 1955, Volume: 113, Issue:3

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Central Nervous System; Codeine; Methadone; Morphine; Rats

1955
[Analgetic effect of morphine, dolsin and mecodin in various ways of application; a pharmacological study].
    Ceskoslovenska farmacie, 1955, Volume: 4, Issue:3

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Meperidine; Methadone; Morphine; Pain; Pain Management

1955
[Action of various pharmacological agents on the exhaustion time and behavior of mice swimming at 20 degrees C. II. Analgesics (morphine, dextromoramide, methadone, pethidine and 3570 CT). Influence of repetition of the test].
    Archives internationales de pharmacodynamie et de therapie, 1962, Feb-01, Volume: 135

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Dextromoramide; Fatigue; Leadership; Meperidine; Methadone; Mice; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed

1962
[Action of Phenampromid on the central nervous system, with special reference to comparison with methadone and morphine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1961, Nov-20, Volume: 57

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Central Nervous System; Methadone; Morphine; Propionates

1961
Antinociceptive interactions of ketamine with morphine or methadone in mononeuropathic rats.
    European journal of pharmacology, 2003, Sep-05, Volume: 477, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Injections, Subcutaneous; Ketamine; Male; Methadone; Mononeuropathies; Morphine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, mu

2003
Methadone for the treatment of pain #75.
    Journal of palliative medicine, 2003, Volume: 6, Issue:4

    Topics: Administration, Oral; Analgesia; Analgesics, Opioid; Drug Administration Schedule; Half-Life; Humans; Methadone; Morphine

2003
Mu-opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Nov-19, Volume: 23, Issue:33

    Topics: Analgesics, Opioid; Animals; Cells, Cultured; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; Humans; In Vitro Techniques; Kidney; Locus Coeruleus; Male; Methadone; Morphine; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Opioid, mu; Transfection

2003
Dosage regimes in the prescription of heroin and other narcotics to chronic opioid addicts in Switzerland--Swiss national cohort study.
    European addiction research, 2004, Volume: 10, Issue:1

    Topics: Administration, Oral; Adult; Ambulatory Care; Clinical Trials as Topic; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Prescriptions; Drug Utilization; Female; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Male; Methadone; Morphine; Narcotics; Outcome and Process Assessment, Health Care; Substance Abuse Detection; Substance Abuse, Intravenous; Switzerland

2004
The action of morphine, pethidine, and amidone upon the intestinal motility of conscious dogs.
    British journal of pharmacology and chemotherapy, 1950, Volume: 5, Issue:4

    Topics: Animals; Consciousness; Dogs; Gastrointestinal Motility; Humans; Intestines; Meperidine; Methadone; Morphine

1950
METHADONE Army develops perfect substitute for morphine.
    Delaware medical journal, 1951, Volume: 23, Issue:1

    Topics: Methadone; Military Medicine; Military Personnel; Morphine; Naval Medicine

1951
[Use of polamidon in morphine withdrawal].
    Medizinische Klinik, 1950, Oct-27, Volume: 45, Issue:43

    Topics: Humans; Methadone; Morphine

1950
The effects of morphine methadone and meperidine on some reflex responses of spinal animals to nociceptive stimulation.
    The Journal of pharmacology and experimental therapeutics, 1951, Volume: 101, Issue:2

    Topics: Animals; Meperidine; Methadone; Morphine; Reflex

1951
[Determination of polamidon and dolantin in the urine, and their separation from morphine].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1951, Volume: 212, Issue:5-6

    Topics: Body Fluids; Meperidine; Methadone; Morphine; Rare Diseases; Retinal Degeneration; Retinal Detachment; Urine

1951
The effect of methadone isomers, morphine, and pentobarbital on the blood glucose of dogs.
    The Journal of pharmacology and experimental therapeutics, 1951, Volume: 102, Issue:4

    Topics: Animals; Barbital; Blood Glucose; Dogs; Methadone; Morphine; Pentobarbital

1951
[Effect of morphine, dolantin and polamidon on the small intestine of man].
    Klinische Wochenschrift, 1951, Sep-01, Volume: 29, Issue:33-34

    Topics: Intestine, Small; Intestines; Meperidine; Methadone; Morphine

1951
A comparison of heat and pressure analgesiometric methods in rats.
    British journal of pharmacology and chemotherapy, 1951, Volume: 6, Issue:4

    Topics: Animals; Hot Temperature; Methadone; Morphine; Pain; Pressure; Rats

1951
Use of n-allylnormorphine in treatment of methadone poisoning in man; report of two cases.
    Journal of the American Medical Association, 1952, Apr-05, Volume: 148, Issue:14

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Hypnotics and Sedatives; Male; Methadone; Morphine; Nalorphine

1952
SUBSTITUTE for morphine.
    Treatment services bulletin. Canada. Department of Veterans' Affairs, 1952, Volume: 7, Issue:1

    Topics: Humans; Methadone; Morphine

1952
Reactions of dogs without neocortex during cycles of addiction to morphine and methadone.
    A.M.A. archives of neurology and psychiatry, 1952, Volume: 67, Issue:5

    Topics: Animals; Behavior, Addictive; Dogs; Humans; Methadone; Morphine; Neocortex; Substance-Related Disorders

1952
Functional inhibition by methadone of N-methyl-D-aspartate receptors expressed in Xenopus oocytes: stereospecific and subunit effects.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:3

    Topics: Animals; Binding, Competitive; Electrophysiology; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Kinetics; Methadone; Morphine; Narcotics; Oocytes; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis

2004
Switching to methadone: 'ad libitum' or fixed dose ratio?
    Palliative medicine, 2004, Volume: 18, Issue:1

    Topics: Analgesics, Opioid; Chronic Disease; Humans; Methadone; Morphine; Neoplasms; Pain; Patient Satisfaction

2004
Withdrawal symptoms during chronic transdermal fentanyl administration managed with oral methadone.
    Journal of pain and symptom management, 2004, Volume: 27, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Substance Withdrawal Syndrome

2004
Modulation of the discriminative stimulus effects of mu opioid agonists in rats: I. Effects of dopamine D2/3 antagonists.
    Behavioural pharmacology, 2004, Volume: 15, Issue:1

    Topics: Animals; Benzazepines; Brain; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Heroin; Methadone; Morphine; Motivation; Nalbuphine; Naphthalenes; Piperazines; Pyrrolidines; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D3; Receptors, Opioid, mu; Salicylamides

2004
Modulation of the discriminative stimulus effects of mu opioid agonists in rats: II. Effects of dopamine D2/3 agonists.
    Behavioural pharmacology, 2004, Volume: 15, Issue:1

    Topics: Animals; Appetitive Behavior; Brain; Discrimination Learning; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Heroin; Male; Methadone; Morphine; Motivation; Nalbuphine; Quinolines; Quinpirole; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Opioid, mu; Tetrahydronaphthalenes

2004
Comparison of the antinociceptive effect of morphine, methadone, buprenorphine and codeine in two substrains of Sprague-Dawley rats.
    European journal of pharmacology, 2004, May-10, Volume: 492, Issue:1

    Topics: Analgesics; Animals; Buprenorphine; Codeine; Injections, Subcutaneous; Male; Methadone; Morphine; Morphine Derivatives; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors

2004
"Opioid creep" is real and may be the cause of "fluid creep".
    Burns : journal of the International Society for Burn Injuries, 2004, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Body Surface Area; Burns; Female; Fentanyl; Fluid Therapy; Humans; Hypnotics and Sedatives; Male; Meperidine; Methadone; Middle Aged; Morphine; Narcotics; Retrospective Studies

2004
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols; Desipramine; Fluvoxamine; Levorphanol; Male; Methadone; Mice; Morphine; Narcotics; Reserpine; Stereoisomerism; Time Factors; Tramadol; Venlafaxine Hydrochloride

2004
[Polamidon as a spasmolytic and analgesic].
    Medizinische Klinik, 1950, Apr-21, Volume: 45, Issue:16

    Topics: Analgesics; Humans; Methadone; Morphine; Pain; Parasympatholytics; Spasm

1950
[Polamidon addiction].
    Deutsche medizinische Wochenschrift (1946), 1950, May-12, Volume: 75, Issue:19

    Topics: Behavior, Addictive; Humans; Methadone; Morphine; Pharmaceutical Preparations

1950
Effects of methadone and morphine of the electroencephalogram of the dog.
    The Journal of pharmacology and experimental therapeutics, 1950, Volume: 98, Issue:4:1

    Topics: Animals; Central Nervous System; Central Nervous System Depressants; Dogs; Electroencephalography; Methadone; Morphine; Nervous System

1950
[Polamidon addiction].
    Arztliche Wochenschrift, 1950, Aug-04, Volume: 5, Issue:30

    Topics: Behavior, Addictive; Humans; Methadone; Morphine; Pharmaceutical Preparations

1950
A comparison of the actions of meperidine, Nu-1196, methadone, morphine, Nu-2206, and metopon upon the intestine and uterus.
    The Journal of pharmacology and experimental therapeutics, 1950, Volume: 99, Issue:3

    Topics: Female; Humans; Intestines; Meperidine; Methadone; Morphinans; Morphine; Uterus

1950
[Abuse of polamidon].
    Medizinische Monatsschrift, 1950, Volume: 4, Issue:8

    Topics: Humans; Mental Disorders; Methadone; Morphine; Pharmaceutical Preparations; Substance-Related Disorders

1950
Intravenous ketamine infusion as an adjuvant to morphine in a 2-year-old with severe cancer pain from metastatic neuroblastoma.
    Journal of pediatric hematology/oncology, 2004, Volume: 26, Issue:10

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Child, Preschool; Codeine; Drug Therapy, Combination; Dyspnea; Fatal Outcome; Female; Hallucinations; Humans; Infusions, Intravenous; Ketamine; Methadone; Morphine; Neuroblastoma; Pain, Intractable; Palliative Care; Quality of Life

2004
Morphine but not fentanyl and methadone affects mitochondrial membrane potential by inducing nitric oxide release in glioma cells.
    Cellular and molecular life sciences : CMLS, 2004, Volume: 61, Issue:23

    Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Cell Line, Tumor; Electron Transport Complex IV; Fentanyl; Free Radicals; Glioma; Humans; Membrane Potentials; Methadone; Microscopy, Fluorescence; Mitochondria; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Signal Transduction; Spectrophotometry; Time Factors

2004
Opioid poisoning deaths in New Zealand (2001-2002).
    The New Zealand medical journal, 2005, Feb-11, Volume: 118, Issue:1209

    Topics: Adolescent; Adult; Aged; Dextropropoxyphene; Drug and Narcotic Control; Drug Prescriptions; Female; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; New Zealand; Poisoning; Suicide

2005
Profound morphine tolerance following high-dose methadone therapy.
    Journal of pain & palliative care pharmacotherapy, 2004, Volume: 18, Issue:4

    Topics: Analgesics; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Male; Methadone; Middle Aged; Morphine; Pain

2004
Opioid poisoning deaths in New Zealand.
    The New Zealand medical journal, 2005, Mar-11, Volume: 118, Issue:1211

    Topics: Humans; Methadone; Morphine; Narcotics; New Zealand; Opioid-Related Disorders

2005
Opioid rotation from methadone: fraught with difficulties.
    Journal of pain and symptom management, 2005, Volume: 29, Issue:4

    Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Liver Neoplasms; Male; Methadone; Morphine; Pain; Treatment Outcome

2005
An opiate cocktail that reduces morphine tolerance and dependence.
    Current biology : CB, 2005, Jun-07, Volume: 15, Issue:11

    Topics: Analysis of Variance; Animals; Biotin; Blotting, Western; Cyclic AMP; Drug Combinations; Drug Tolerance; Endocytosis; Immunohistochemistry; Luciferases; Methadone; Morphine; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substance-Related Disorders

2005
Comparative actions of the opioid analgesics morphine, methadone and codeine in rat models of peripheral and central neuropathic pain.
    Pain, 2005, Volume: 116, Issue:3

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Codeine; Disease Models, Animal; Male; Methadone; Morphine; Motor Activity; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Rotarod Performance Test; Sciatic Neuropathy; Spinal Cord Injuries; Time Factors

2005
Effect of repeated administrations of heroin, naltrexone, methadone, and alcohol on morphine glucuronidation in the rat.
    Psychopharmacology, 2005, Volume: 182, Issue:1

    Topics: Animals; Ethanol; Heroin; Heroin Dependence; Male; Methadone; Microsomes, Liver; Morphine; Morphine Derivatives; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

2005
Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice.
    The journal of pain, 2005, Volume: 6, Issue:7

    Topics: Analgesia; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyrrolidinones; Reaction Time; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate

2005
Simplified methadone conversion.
    Journal of palliative medicine, 2005, Volume: 8, Issue:3

    Topics: Administration, Oral; Algorithms; Analgesics, Opioid; Humans; Methadone; Morphine; Palliative Care; United States

2005
Morphine tolerance as a function of ratio schedule: response requirement or unit price?
    Journal of the experimental analysis of behavior, 2005, Volume: 83, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Columbidae; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Female; Methadone; Morphine; Narcotics; Reinforcement Schedule; Reinforcement, Psychology

2005
Reversal of morphine, methadone and heroin induced effects in mice by naloxone methiodide.
    Life sciences, 2006, Jan-11, Volume: 78, Issue:7

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Drug Interactions; Female; Heroin; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Plethysmography, Whole Body; Quaternary Ammonium Compounds; Respiration; Respiratory Insufficiency; Substance Withdrawal Syndrome

2006
A retrospective study of length of hospital stay in infants treated for neonatal abstinence syndrome with methadone versus oral morphine preparations.
    Advances in neonatal care : official journal of the National Association of Neonatal Nurses, 2005, Volume: 5, Issue:5

    Topics: Administration, Oral; Female; Hospitalization; Humans; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Retrospective Studies

2005
Opiate maintenance alternatives: new studies.
    The Harvard mental health letter, 2005, Volume: 22, Issue:3

    Topics: Buprenorphine; Humans; Methadone; Morphine; Narcotic Antagonists; Narcotics; Opioid-Related Disorders

2005
HPLC-DAD determination of opioids, cocaine and their metabolites in plasma.
    Forensic science international, 2006, Aug-10, Volume: 161, Issue:1

    Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Humans; Male; Methadone; Morphine; Morphine Derivatives; Pyrrolidines

2006
Management of neonatal abstinence syndrome in neonatal intensive care units: a national survey.
    Journal of perinatology : official journal of the California Perinatal Association, 2006, Jan-01, Volume: 26, Issue:1

    Topics: Humans; Hypnotics and Sedatives; Infant, Newborn; Injections, Intravenous; Intensive Care Units, Neonatal; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Psychomotor Performance; Surveys and Questionnaires; Treatment Outcome

2006
Opioid switching from oral slow release morphine to oral methadone may improve pain control in chronic non-malignant pain: a nine-month follow-up study.
    Palliative medicine, 2006, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Morphine; Pain; Patient Satisfaction; Prospective Studies

2006
The effect of FDA approval of a generic competitor to OxyContin (oxycodone HCl controlled-release) tablets on the abuse of oxycodone.
    Drug and alcohol dependence, 2006, Sep-15, Volume: 84, Issue:2

    Topics: Analgesics, Opioid; Catchment Area, Health; Delayed-Action Preparations; Drug Approval; Drug Prescriptions; Drugs, Generic; Humans; Hydrocodone; Methadone; Morphine; Oxycodone; Poison Control Centers; Population Surveillance; Prevalence; Substance-Related Disorders; United States; United States Food and Drug Administration

2006
Prescription drug dependence and evolving beliefs about chronic pain management.
    The American journal of psychiatry, 2006, Volume: 163, Issue:4

    Topics: Adult; Analgesics, Opioid; Chronic Disease; Drug Prescriptions; Drug Tolerance; Drug Utilization; Female; Humans; Hyperalgesia; Methadone; Morphine; Pain; Physician-Patient Relations; Receptors, Opioid; Substance-Related Disorders

2006
Morphine, oxycodone, methadone and its enantiomers in different models of nociception in the rat.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:6

    Topics: Acute Disease; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Male; Methadone; Morphine; Neuralgia; Oxycodone; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, mu; Spinal Nerves

2006
Anesthesia and pain management for pediatric patients with dystrophic epidermolysis bullosa.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:4

    Topics: Adolescent; Anesthesia, General; Child; Child, Preschool; Conscious Sedation; Epidermolysis Bullosa Dystrophica; Female; Humans; Hydromorphone; Infant; Male; Methadone; Morphine; Pain; Perioperative Care; Postoperative Complications; Preoperative Care; Retrospective Studies

2006
Opiate pharmacology of intrathecal granulomas.
    Anesthesiology, 2006, Volume: 105, Issue:3

    Topics: Analgesics, Opioid; Animals; Dogs; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Granuloma; Injections, Spinal; Male; Maximum Tolerated Dose; Methadone; Morphine; Spinal Cord

2006
Changes to the daily pattern of methadone-related deaths in England and Wales, 1993-2003.
    Journal of public health (Oxford, England), 2006, Volume: 28, Issue:4

    Topics: Death Certificates; Drug Overdose; England; Heroin; Holidays; Humans; Methadone; Morphine; Narcotics; Periodicity; Risk Assessment; Substance Abuse Treatment Centers; Substance-Related Disorders; Time Factors; Wales

2006
Trends and geographic variation of opiate medication use in state Medicaid fee-for-service programs, 1996 to 2002.
    Medical care, 2006, Volume: 44, Issue:11

    Topics: Analgesics, Opioid; Data Interpretation, Statistical; Drug Prescriptions; Drug Utilization; Fee-for-Service Plans; Humans; Hydrocodone; Medicaid; Methadone; Models, Theoretical; Morphine; Oxycodone; Pain; Practice Patterns, Physicians'; United States

2006
Effects of subcutaneous methadone, morphine, buprenorphine or saline on thermal and pressure thresholds in cats.
    Journal of veterinary pharmacology and therapeutics, 2006, Volume: 29, Issue:6

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Cats; Female; Hot Temperature; Injections, Subcutaneous; Male; Methadone; Morphine; Pain; Pain Measurement; Pressure

2006
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior.
    Psychopharmacology, 2007, Volume: 190, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Indophenol; Levorphanol; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Stereotyped Behavior; Tics; Tourette Syndrome; Tramadol; Triazoles

2007
Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics.
    Anesthesiology, 2007, Volume: 106, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Heroin; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Male; Methadone; Morphine; Neuralgia; Pain; Rats; Rats, Inbred F344; Self Administration

2007
Characterization of the antinociceptive and pronociceptive effects of methadone in rats.
    Anesthesiology, 2007, Volume: 106, Issue:3

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Male; Methadone; Morphine; Nociceptors; Rats; Rats, Sprague-Dawley; Sex Factors; Time Factors

2007
Medicating "Margaret".
    The Journal of clinical ethics, 2006,Winter, Volume: 17, Issue:4

    Topics: Advance Directives; Alzheimer Disease; Analgesics, Opioid; Antipsychotic Agents; Electroconvulsive Therapy; Female; Fentanyl; Hospice Care; Humans; Lorazepam; Methadone; Middle Aged; Morphine; Oxycodone; Pain; Palliative Care; Psychomotor Agitation; Right to Die

2006
Blockade of morphine-induced behavioral sensitization by a combination of amisulpride and RB101, comparison with classical opioid maintenance treatments.
    British journal of pharmacology, 2007, Volume: 151, Issue:1

    Topics: Amisulpride; Animals; Behavior, Animal; Buprenorphine; Disulfides; Male; Methadone; Mice; Morphine; Motor Activity; Opioid-Related Disorders; Phenylalanine; Sulpiride

2007
The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain.
    Pharmacology, 2007, Volume: 79, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics, Opioid; Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Methadone; Morphine; Morphine Dependence; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

2007
Development and validation of the Cozart DDS oral fluid collection device.
    Forensic science international, 2007, Aug-06, Volume: 170, Issue:2-3

    Topics: Amphetamines; Automobile Driving; Cocaine; Dopamine Uptake Inhibitors; Dronabinol; Forensic Toxicology; Hallucinogens; Humans; Hypnotics and Sedatives; Methadone; Morphine; Narcotics; Saliva; Substance Abuse Detection; Temazepam

2007
Prescribing patterns and purchasing costs of long-acting opioids over nine years at an academic oncology hospital.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Aug-01, Volume: 64, Issue:15

    Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Costs; Drug Utilization; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Time Factors

2007
Microwave-assisted extraction and HPLC-DAD determination of drugs of abuse in human plasma.
    Journal of analytical toxicology, 2007, Volume: 31, Issue:7

    Topics: Calibration; Chromatography, High Pressure Liquid; Cocaine; Codeine; Forensic Medicine; Humans; Illicit Drugs; Methadone; Microwaves; Morphine; Pyrrolidines; Reproducibility of Results; Solvents; Spectrophotometry, Atomic; Substance Abuse Detection

2007
NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats.
    Psychopharmacology, 2008, Volume: 196, Issue:3

    Topics: Animals; Behavior, Animal; Buprenorphine; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Memantine; Methadone; Morphine; Motor Activity; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2008
Hospital morphine preparation for abstinence syndrome in newborns exposed to buprenorphine or methadone.
    Pharmacy world & science : PWS, 2008, Volume: 30, Issue:3

    Topics: Buprenorphine; Chromatography, High Pressure Liquid; Drug Contamination; Drug Stability; Female; Humans; Infant, Newborn; Methadone; Morphine; Narcotic Antagonists; Narcotics; Neonatal Abstinence Syndrome; Pharmaceutical Solutions; Pregnancy; Prospective Studies

2008
Buprenorphine + naloxone: new combination. Opiate dependence: no proof of reduced risk of self-administered injection.
    Prescrire international, 2007, Volume: 16, Issue:92

    Topics: Administration, Sublingual; Analgesics, Opioid; Buprenorphine; Drug Therapy, Combination; Finland; France; Heroin Dependence; Humans; Methadone; Morphine; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Patient Compliance; Patient Dropouts; Randomized Controlled Trials as Topic; Self Administration; Treatment Outcome

2007
Levorphanol revisited.
    Journal of palliative medicine, 2007, Volume: 10, Issue:6

    Topics: Analgesics, Opioid; Levorphanol; Methadone; Morphine

2007
A comparison of certain actions of demerol and methadone.
    California medicine, 1949, Volume: 70, Issue:1

    Topics: Humans; Meperidine; Methadone; Morphine; Narcotics

1949
Hindlimb reflexes of chronic spinal dots during cycles of addiction to morphine and methadon.
    The Journal of pharmacology and experimental therapeutics, 1948, Volume: 94, Issue:4

    Topics: Animals; Behavior, Addictive; Hindlimb; Methadone; Morphine; Reflex

1948
Inhibition of succinic oxidase system by meperidine, methadon, morphine, and codeine.
    The Journal of pharmacology and experimental therapeutics, 1949, Volume: 95, Issue:2

    Topics: Codeine; Coloring Agents; Meperidine; Methadone; Morphine; Oxidoreductases; Peroxidase; Peroxidases; Succinate Dehydrogenase

1949
Comparative investigations in to the analgesic effects of morphine and d, 1-6-dimethylamino-4,4-diphenyl-3-heptanone hydrochloride.
    Acta pharmacologica et toxicologica, 1949, Volume: 5, Issue:1

    Topics: Analgesics; Biphenyl Compounds; Diphenhydramine; Humans; Ketones; Methadone; Morphine

1949
The addiction liability of methadon (amidone, dolophine, 10820) and its use in the treatment of the morphine abstinence syndrome.
    The American journal of psychiatry, 1949, Volume: 105, Issue:12

    Topics: Behavior, Addictive; Humans; Industry; Methadone; Morphine; Morphine Dependence; Occupations; Syndrome

1949
Prescribing methadone for pain management in end-of-life care.
    The Journal of the American Osteopathic Association, 2005, Volume: 105, Issue:3 Suppl 1

    Topics: Drug Interactions; Humans; Methadone; Morphine; Pain; Palliative Care; Terminal Care

2005
OCCURRENCE IN RODENTS OF REVERSIBLE DRUG-INDUCED OPACITIES OF THE LENS.
    The British journal of ophthalmology, 1961, Volume: 45, Issue:6

    Topics: Analgesics, Opioid; Animals; Cataract; Chickens; Guinea Pigs; Humans; Injections, Subcutaneous; Lens Capsule, Crystalline; Lens, Crystalline; Meperidine; Methadone; Mice; Morphine; Pupil; Rats; Recovery of Function

1961
Methadone: does it really have low efficacy at micro-opioid receptors?
    Neuroreport, 2008, Mar-26, Volume: 19, Issue:5

    Topics: Animals; Animals, Newborn; Cell Line, Transformed; Drug Interactions; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Locus Coeruleus; Membrane Potentials; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Protein Binding; Rats; Receptors, Opioid, mu; Transfection

2008
Chronic exposure of human macrophages in vitro to morphine and methadone induces a putative tolerant/dependent state.
    Journal of neuroimmunology, 2008, May-30, Volume: 196, Issue:1-2

    Topics: Adolescent; Adult; Analysis of Variance; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Macrophages; Male; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Substance Withdrawal Syndrome; Time Factors

2008
Morphine and methadone pre-exposures differently modify brain regional Fos protein expression and locomotor activity responses to morphine challenge in the rat.
    Drug and alcohol dependence, 2008, Sep-01, Volume: 97, Issue:1-2

    Topics: Animals; Brain Chemistry; Cerebral Cortex; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Methadone; Morphine; Motor Activity; Narcotics; Neostriatum; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley

2008
Neonatal abstinence syndrome.
    Indian journal of pediatrics, 2008, Volume: 75, Issue:9

    Topics: Female; Humans; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Methadone; Morphine; Mothers; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; Scotland; Time Factors; Treatment Outcome

2008
Mu-opioid receptor activation in live cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:10

    Topics: Animals; Cell Membrane; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Green Fluorescent Proteins; Humans; Membrane Lipids; Methadone; Models, Biological; Morphine; PC12 Cells; Rats; Receptors, Opioid, mu

2008
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia.
    Brain, behavior, and immunity, 2008, Volume: 22, Issue:8

    Topics: Analgesia; Analgesics, Opioid; Animals; Catheters, Indwelling; Chemokine CX3CL1; Cytokines; Hyperalgesia; Injections, Spinal; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Male; Methadone; Morphine; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Time Factors

2008
Differential activation and trafficking of micro-opioid receptors in brain slices.
    Molecular pharmacology, 2008, Volume: 74, Issue:4

    Topics: Analgesics, Opioid; Animals; Brain; Chelating Agents; Egtazic Acid; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Fluorescent Antibody Technique, Direct; Locus Coeruleus; Methadone; Mice; Mice, Knockout; Mice, Transgenic; Morphine; Neurons; Oxycodone; Oxymorphone; Protein Transport; Radioligand Assay; Receptors, Opioid, mu; Recombinant Fusion Proteins; Time Factors

2008
Nails of newborns in monitoring drug exposure during pregnancy.
    Forensic science international, 2008, Aug-06, Volume: 179, Issue:2-3

    Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Cotinine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methadone; Morphine; Nails; Narcotics; Nicotine; Nicotinic Agonists; Pregnancy; Smoking

2008
Management of acute pain in methadone maintenance therapy in-patients.
    Drug and alcohol review, 2008, Volume: 27, Issue:5

    Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Australia; Dose-Response Relationship, Drug; Female; Humans; Inpatients; Male; Methadone; Morphine; Pain; Pain Measurement; Retrospective Studies; Substance Abuse Treatment Centers

2008
The underrecognized toll of prescription opioid abuse on young children.
    Annals of emergency medicine, 2009, Volume: 53, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Buprenorphine; Child, Preschool; Female; Humans; Hydrocodone; Hydromorphone; Infant; Infant, Newborn; Male; Methadone; Morphine; Oxycodone; Poisoning; Prescription Drugs; United States

2009
So much for harm reduction techniques reducing drug deaths.
    BMJ (Clinical research ed.), 2008, Sep-16, Volume: 337

    Topics: Adult; Harm Reduction; Heroin Dependence; Humans; Methadone; Morphine; Narcotics

2008
Influence of amidone, morphine and strychine on the Straub-tail-test of white mice.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Animals; Methadone; Mice; Morphine; Morphine Derivatives

1948
Analgesic effects in human subjects of morphine, meperidina and methadon.
    Journal of the American Medical Association, 1948, Jun-12, Volume: 137, Issue:7

    Topics: Analgesics; Humans; Meperidine; Methadone; Morphine; Morphine Derivatives

1948
An electroencephalographic analysis of the action of amidone, morphine and strychnine on the central nervous system.
    Archives internationales de pharmacodynamie et de therapie, 1948, Apr-15, Volume: 76, Issue:2

    Topics: Central Nervous System; Central Nervous System Depressants; Electroencephalography; Humans; Methadone; Morphine; Strychnine

1948
Pharmacology of methadone and related compounds.
    Annals of the New York Academy of Sciences, 1948, Nov-01, Volume: 51, Issue:Art 1

    Topics: Humans; Methadone; Morphine; Morphine Derivatives

1948
Observations on the comparative pharmacologic actions of 6-dimethylamino-4,4-diphenyl-3-heptanone (amidone) and morphine.
    The Journal of pharmacology and experimental therapeutics, 1948, Volume: 92, Issue:3

    Topics: Biphenyl Compounds; Ketones; Methadone; Morphine

1948
Acute vascular tolerance to morphine, isonipecaine (demerol) and methadon (amidone) in the dog.
    The Journal of pharmacology and experimental therapeutics, 1948, Volume: 92, Issue:4

    Topics: Animals; Blood Vessels; Dogs; Drug Tolerance; Immune Tolerance; Meperidine; Methadone; Morphine

1948
Physical dependence liability of drugs of the methadon series and of 6-methyldihydromorphine.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Behavior, Addictive; Methadone; Morphine; Morphine Derivatives; Substance-Related Disorders

1948
Electroencephalographic analysis of action of amidone, morphine and strychnine on the central nervous system.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Central Nervous System; Central Nervous System Depressants; Electroencephalography; Humans; Methadone; Morphine; Morphine Derivatives; Strychnine

1948
A comparison of side actions and analgesic effects of morphine, amidone, (4-4-diphenyl-6-dimethylamino-heptanone-3) and its isomers in man.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Analgesics; Biphenyl Compounds; Diphenhydramine; Isomerism; Ketones; Methadone; Morphine; Morphine Derivatives

1948
[Analgesics and palliative care].
    Revue medicale de Bruxelles, 2008, Volume: 29, Issue:4

    Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Methadone; Morphine; Neoplasms; Pain; Palliative Care; Patient Care Team; Terminal Care

2008
Slow-release oral morphine for maintenance treatment of opioid addicts intolerant to methadone or with inadequate withdrawal suppression.
    Addiction (Abingdon, England), 2008, Volume: 103, Issue:11

    Topics: Adult; Delayed-Action Preparations; Female; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Opioid-Related Disorders; Prospective Studies; Quality of Life; Substance Withdrawal Syndrome; Treatment Outcome

2008
European pain management discussion forum.
    Journal of pain & palliative care pharmacotherapy, 2008, Volume: 22, Issue:3

    Topics: Analgesics, Opioid; Arrhythmias, Cardiac; Europe; Herpes Zoster; Humans; Methadone; Morphine; Neuralgia, Postherpetic; Opioid-Related Disorders; Pain; Pain, Postoperative

2008
Hyperalgesia in opioid-managed chronic pain and opioid-dependent patients.
    The journal of pain, 2009, Volume: 10, Issue:3

    Topics: Adult; Analgesics, Opioid; Chronic Disease; Drug Tolerance; Female; Humans; Hyperalgesia; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Pain; Pain Measurement; Pain Threshold

2009
Direct subunit-dependent multimodal 5-hydroxytryptamine3 receptor antagonism by methadone.
    Molecular pharmacology, 2009, Volume: 75, Issue:4

    Topics: Cell Line; Dose-Response Relationship, Drug; Humans; Methadone; Morphine; Protein Subunits; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Stereoisomerism

2009
Morphine-methadone opioid rotation in cancer patients: analysis of dose ratio predicting factors.
    Journal of pain and symptom management, 2009, Volume: 37, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Palliative Care; Predictive Value of Tests

2009
Management of neonatal abstinence syndrome: a national survey and review of practice.
    Archives of disease in childhood. Fetal and neonatal edition, 2009, Volume: 94, Issue:4

    Topics: Anticonvulsants; Breast Feeding; Drug Administration Schedule; Health Care Surveys; Humans; Infant Care; Infant, Newborn; Ireland; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Patient Discharge; Professional Practice; United Kingdom

2009
Methadone antinociception is dependent on peripheral opioid receptors.
    The journal of pain, 2009, Volume: 10, Issue:4

    Topics: Analgesics, Opioid; Animals; Drug Administration Routes; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Species Specificity

2009
Frequency, indications, outcomes, and predictive factors of opioid switching in an acute palliative care unit.
    Journal of pain and symptom management, 2009, Volume: 37, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Pain; Palliative Care; Prospective Studies; Treatment Outcome

2009
Generation and utilization of anti-drug monoclonal antibodies for screening of 36 drug users by dot-ELISA.
    Hybridoma (2005), 2009, Volume: 28, Issue:2

    Topics: Antibodies, Monoclonal; Barbital; Enzyme-Linked Immunosorbent Assay; Humans; Methadone; Methamphetamine; Morphine; Phencyclidine; Substance Abuse Detection

2009
Route of administration influences substitution patterns in rats trained to discriminate methadone vs. vehicle.
    Drug and alcohol dependence, 2009, Aug-01, Volume: 103, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Choice Behavior; Conditioning, Operant; Discrimination, Psychological; Heroin; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pharmaceutical Vehicles; Rats; Rats, Sprague-Dawley; Stereoisomerism

2009
Methadone is substantially less effective than morphine in modifying locomotor and brain Fos responses to subsequent methadone challenge in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2009, Aug-31, Volume: 33, Issue:6

    Topics: Animals; Brain Chemistry; Male; Methadone; Morphine; Motor Activity; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley

2009
Simultaneous quantification of methadone, cocaine, opiates, and metabolites in human placenta by liquid chromatography-mass spectrometry.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:5

    Topics: Adult; Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Female; Humans; Methadone; Morphine; Morphine Derivatives; Placenta; Pregnancy; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Young Adult

2009
Challenging small human hepatocytes with opiates: further characterization of a novel prototype bioartificial liver.
    Tissue engineering. Part A, 2010, Volume: 16, Issue:3

    Topics: Blotting, Western; Cell Count; Cell Culture Techniques; Cell Extracts; Cell Survival; Cells, Cultured; Hepatocytes; Humans; Liver, Artificial; Methadone; Morphine; Opiate Alkaloids

2010
Characteristics and comparative severity of respiratory response to toxic doses of fentanyl, methadone, morphine, and buprenorphine in rats.
    Toxicology letters, 2009, Dec-15, Volume: 191, Issue:2-3

    Topics: Animals; Blood Gas Analysis; Buprenorphine; Catheterization; Fentanyl; Lactic Acid; Male; Methadone; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Narcotics; Plethysmography, Whole Body; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Respiratory Insufficiency; Respiratory Mechanics

2009
Treatment of neonatal abstinence syndrome with clonidine and chloral hydrate.
    Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:2

    Topics: Blood Pressure; Chloral Hydrate; Clonidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Retrospective Studies; Treatment Outcome

2010
Acute methadone treatment reduces myocardial infarct size via the delta-opioid receptor in rats during reperfusion.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Methadone; Morphine; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Time Factors

2009
Determinants of successful chronic hepatitis C case finding among patients receiving opioid maintenance treatment in a primary care setting.
    Addiction (Abingdon, England), 2009, Volume: 104, Issue:12

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Family Practice; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Methadone; Morphine; Narcotics; Polymerase Chain Reaction; Regression Analysis; Retrospective Studies; Substance Abuse, Intravenous; Switzerland

2009
Gas chromatography-mass spectrometry assay for the simultaneous quantification of drugs of abuse in human placenta at 12th week of gestation.
    Forensic science international, 2010, Mar-20, Volume: 196, Issue:1-3

    Topics: Abortion, Induced; Amphetamines; Cocaine; Cotinine; Dronabinol; Female; Forensic Toxicology; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Maternal Exposure; Maternal-Fetal Exchange; Methadone; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Nicotine; Placenta; Pregnancy; Pregnancy Trimester, First; Specimen Handling; Substance Abuse Detection

2010
A reduction in blood morphine concentrations amongst heroin overdose fatalities associated with a sustained reduction in street heroin purity.
    Forensic science international, 2010, May-20, Volume: 198, Issue:1-3

    Topics: Adult; Australia; Benzodiazepines; Central Nervous System Depressants; Drug Contamination; Drug Overdose; Ethanol; Female; Forensic Toxicology; Heroin; Humans; Illicit Drugs; Male; Methadone; Morphine; Narcotics

2010
Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences.
    Neuroscience, 2010, May-19, Volume: 167, Issue:3

    Topics: Analgesics, Opioid; Animals; Gliosis; Hyperalgesia; Immunity, Innate; Inflammation; Inflammation Mediators; Injections, Spinal; Interleukin-1; Isomerism; Lymphocyte Antigen 96; Male; Methadone; Microglia; Morphine; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Toll-Like Receptor 4

2010
A KCNJ6 (Kir3.2, GIRK2) gene polymorphism modulates opioid effects on analgesia and addiction but not on pupil size.
    Pharmacogenetics and genomics, 2010, Volume: 20, Issue:5

    Topics: Administration, Oral; Analgesia; Analgesics, Opioid; Animals; Brain; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genotype; Heroin; Japan; Methadone; Morphine; Polymorphism, Genetic; Rats; Rats, Wistar; Receptors, Opioid

2010
Acute vascular tolerance to morphine, demerol, and 1,1-diphenyl-1-(dimethylamino-isopropyl) butanone-2 (amidone) in the dog.
    Federation proceedings, 1947, Volume: 6, Issue:1

    Topics: Animals; Biphenyl Compounds; Butanones; Dogs; Drug Tolerance; Humans; Meperidine; Methadone; Morphine

1947
Comparative toxicology of intentional and accidental heroin overdose.
    Journal of forensic sciences, 2010, Volume: 55, Issue:4

    Topics: Accidents; Adult; Body Mass Index; Central Nervous System Depressants; Cocaine; Drug Overdose; Ethanol; Female; Forensic Toxicology; Heroin; Humans; Liver; Lymphocytes; Male; Methadone; Morphine; Narcotics; Sex Distribution; Suicide

2010
Topical methadone and meperidine analgesic synergy in the mouse.
    European journal of pharmacology, 2010, Jul-25, Volume: 638, Issue:1-3

    Topics: Administration, Cutaneous; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Lidocaine; Male; Meperidine; Methadone; Mice; Mice, Inbred Strains; Morphine; Pain Measurement

2010
Enhancement of tolerance development to morphine in rats prenatally exposed to morphine, methadone, and buprenorphine.
    Journal of biomedical science, 2010, Jun-07, Volume: 17

    Topics: Analgesics; Animals; Buprenorphine; Disease Models, Animal; Drug Tolerance; Female; Heroin Dependence; Humans; Male; Methadone; Morphine; Morphine Dependence; Pain Measurement; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

2010
Gender and NAS: does sex matter?
    Drug and alcohol dependence, 2010, Nov-01, Volume: 112, Issue:1-2

    Topics: Analgesics, Opioid; Female; Humans; Infant, Newborn; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Retrospective Studies; Risk Factors; Sex Characteristics

2010
The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.
    Neuropharmacology, 2011, Volume: 60, Issue:1

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Arrestins; beta-Arrestins; Drug Tolerance; Fentanyl; Hot Temperature; Male; Methadone; Mice; Mice, Knockout; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Pain Threshold; Receptors, Opioid, mu

2011
A hybrid liquid chromatography-mass spectrometry strategy in a forensic laboratory for opioid, cocaine and amphetamine classes in human urine using a hybrid linear ion trap-triple quadrupole mass spectrometer.
    Journal of chromatography. A, 2010, Oct-29, Volume: 1217, Issue:44

    Topics: Amphetamines; Calibration; Chromatography, Liquid; Cocaine; Humans; Linear Models; Mass Spectrometry; Methadone; Morphine; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection

2010
CYP2B6 and OPRM1 gene variations predict methadone-related deaths.
    Addiction biology, 2011, Volume: 16, Issue:1

    Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Cause of Death; Cytochrome P-450 CYP2B6; Drug Synergism; Gene Frequency; Genetic Carrier Screening; Genetic Predisposition to Disease; Genetic Testing; Genetic Variation; Genotype; Heroin Dependence; Humans; Methadone; Morphine; Narcotics; Opiate Substitution Treatment; Oxidoreductases, N-Demethylating; Receptors, Opioid, mu; Risk Factors

2011
Diverse behavioral, monoaminergic and Fos protein responses to opioids in Warsaw high-alcohol preferring and Warsaw low-alcohol preferring rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Mar-30, Volume: 35, Issue:2

    Topics: Alcohol Drinking; Analgesics, Opioid; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Disease Models, Animal; Dopamine; Male; Methadone; Morphine; Motor Activity; Opioid-Related Disorders; Proto-Oncogene Proteins c-fos; Rats; Serotonin

2011
Oral fluid is a viable alternative for monitoring drug abuse: detection of drugs in oral fluid by liquid chromatography-tandem mass spectrometry and comparison to the results from urine samples from patients treated with Methadone or Buprenorphine.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:1

    Topics: Benzodiazepines; Buprenorphine; Chromatography, Liquid; Drug Monitoring; Humans; Illicit Drugs; Methadone; Morphine; Morphine Derivatives; Saliva; Substance Abuse Detection; Tandem Mass Spectrometry

2011
Oral fluid results compared to self reports of recent cocaine and heroin use by methadone maintenance patients.
    Forensic science international, 2012, Feb-10, Volume: 215, Issue:1-3

    Topics: Cocaine; Cocaine-Related Disorders; Codeine; Heroin; Heroin Dependence; Humans; Methadone; Morphine; Morphine Derivatives; Narcotics; Opiate Substitution Treatment; Saliva; Self Report; Substance Abuse Detection

2012
Choosing the unit of measurement counts: the use of oral morphine equivalents in studies of opioid consumption is a useful addition to defined daily doses.
    Palliative medicine, 2011, Volume: 25, Issue:7

    Topics: Administration, Oral; Analgesics, Opioid; Cooperative Behavior; Databases, Factual; Drug Utilization; Fentanyl; Humans; Methadone; Morphine; Norway; Pain; Pain Measurement; Therapeutic Equivalency; World Health Organization

2011
Trends and pattern of drug abuse deaths in Maryland teenagers.
    Journal of forensic sciences, 2011, Volume: 56, Issue:4

    Topics: Adolescent; Age Distribution; Black People; Butanes; Cause of Death; Chlorofluorocarbons, Methane; Cocaine; Female; Forensic Pathology; Forensic Toxicology; Hepatitis B Antibodies; Heroin; HIV Antibodies; Humans; Male; Maryland; Methadone; Morphine; Myocarditis; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Nitrous Oxide; Pneumonia; Propane; Retrospective Studies; Sex Distribution; Substance-Related Disorders; White People

2011
Recovery from mu-opioid receptor desensitization after chronic treatment with morphine and methadone.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Mar-23, Volume: 31, Issue:12

    Topics: Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Brain Chemistry; Endocytosis; G-Protein-Coupled Receptor Kinase 2; Male; Methadone; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Morphine; Narcotics; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

2011
Clinical characteristics and risk behavior as a function of HIV status among heroin users enrolled in methadone treatment in northern Taiwan.
    Substance abuse treatment, prevention, and policy, 2011, Apr-08, Volume: 6

    Topics: Adult; Dose-Response Relationship, Drug; Female; Hepatitis C; Heroin Dependence; HIV Seronegativity; HIV Seropositivity; Humans; Interviews as Topic; Male; Mental Disorders; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Quality of Life; Risk-Taking; Sexual Behavior; Socioeconomic Factors; Taiwan

2011
Comparative mortality among Department of Veterans Affairs patients prescribed methadone or long-acting morphine for chronic pain.
    Pain, 2011, Volume: 152, Issue:8

    Topics: Adult; Aged; Analgesics, Opioid; Benzodiazepines; Cohort Studies; Drug Delivery Systems; Female; Humans; Male; Methadone; Middle Aged; Morphine; Pain; Prescription Drugs; Retrospective Studies; Sensitivity and Specificity; Survival Analysis; Treatment Outcome; United States; United States Department of Veterans Affairs

2011
Drug screening of whole blood by ultra-performance liquid chromatography-tandem mass spectrometry.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:5

    Topics: Buprenorphine; Chromatography, Liquid; Cocaine; Codeine; Dronabinol; Ethylmorphine; Humans; Illicit Drugs; Methadone; Morphine; Oxycodone; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry

2011
Drug overdose deaths--Florida, 2003-2009.
    MMWR. Morbidity and mortality weekly report, 2011, Jul-08, Volume: 60, Issue:26

    Topics: Alprazolam; Cause of Death; Cocaine; Drug Overdose; Florida; Humans; Illicit Drugs; Methadone; Morphine; Mortality; Oxycodone; Prescription Drugs

2011
Drug-related death in Denmark in 2007.
    Danish medical bulletin, 2011, Volume: 58, Issue:8

    Topics: Adolescent; Adult; Age Distribution; Amphetamines; Denmark; Female; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Prevalence; Risk Factors; Substance-Related Disorders; Young Adult

2011
Inconsistencies in opioid equianalgesic ratios: clinical and research implications.
    Journal of pain & palliative care pharmacotherapy, 2008, Volume: 22, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Delayed-Action Preparations; Drug Dosage Calculations; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Randomized Controlled Trials as Topic

2008
Chronic methadone treatment shows a better cost/benefit ratio than chronic morphine in mice.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

    Topics: Analgesics, Opioid; Animals; Area Under Curve; Dose-Response Relationship, Drug; Drug Tolerance; Endocytosis; Gene Knock-In Techniques; Methadone; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Mutation; Naloxone; Pain; Pain Measurement; Pain Threshold; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Substance-Related Disorders

2012
Is maternal opioid use hazardous to breast-fed infants?
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:1

    Topics: Age Factors; Analgesics, Opioid; Breast Feeding; Buprenorphine; Codeine; Female; Humans; Hydrocodone; Infant; Infant, Newborn; Meperidine; Methadone; Milk, Human; Morphine; Oxycodone

2012
Physical compatibility of binary and ternary mixtures of morphine and methadone with other drugs for parenteral administration in palliative care.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012, Volume: 20, Issue:10

    Topics: Analgesics, Opioid; Drug Combinations; Drug Interactions; Humans; Infusions, Parenteral; Ketorolac; Methadone; Morphine; Palliative Care; Reference Standards; Reproducibility of Results

2012
Stop and go strategy for opioid switching requires flexibility.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:6

    Topics: Analgesics, Opioid; Drug Substitution; Female; Humans; Male; Methadone; Morphine; Neoplasms; Oxycodone; Pain

2012
A rooming-in program to mitigate the need to treat for opiate withdrawal in the newborn.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2012, Volume: 34, Issue:5

    Topics: Adult; Breast Feeding; Heroin Dependence; Humans; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Rooming-in Care; Young Adult

2012
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:6

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Hippocampus; Learning; Male; Memory; Methadone; Mitogen-Activated Protein Kinase 1; Morphine; Phosphorylation; Rats; Rats, Wistar

2012
UGT2B7 genetic polymorphisms are associated with the withdrawal symptoms in methadone maintenance patients.
    Pharmacogenomics, 2012, Volume: 13, Issue:8

    Topics: Adult; Amitriptyline; Female; Genetic Association Studies; Glucuronosyltransferase; Haplotypes; Heroin Dependence; Humans; Linkage Disequilibrium; Male; Methadone; Middle Aged; Morphine; Polymorphism, Single Nucleotide; Pyrrolidines; Substance Withdrawal Syndrome; Taiwan

2012
(1) H-nuclear magnetic resonance-based metabonomic analysis of brain in rhesus monkeys with morphine treatment and withdrawal intervention.
    Journal of neuroscience research, 2012, Volume: 90, Issue:11

    Topics: Animals; Brain; Disease Models, Animal; Female; Macaca mulatta; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methadone; Morphine; Morphine Dependence; Narcotics; Substance Withdrawal Syndrome

2012
Comparison of fatal poisonings by prescription opioids.
    Forensic science international, 2012, Oct-10, Volume: 222, Issue:1-3

    Topics: Accidents; Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Central Nervous System Depressants; Codeine; Dextropropoxyphene; Drug Overdose; Ethanol; Fentanyl; Finland; Forensic Toxicology; Humans; Hypnotics and Sedatives; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Poisoning; Prescription Drug Misuse; Suicide; Tramadol; Young Adult

2012
Methadone but not morphine inhibits lubiprostone-stimulated Cl- currents in T84 intestinal cells and recombinant human ClC-2, but not CFTR Cl- currents.
    Cell biochemistry and biophysics, 2013, Volume: 66, Issue:1

    Topics: Alprostadil; Biological Transport; Cadmium Chloride; Chloride Channels; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Lubiprostone; Methadone; Morphine; Naloxone; Patch-Clamp Techniques; Recombinant Proteins; Time Factors; Transfection

2013
Unpredictable absorption of oral opioid medications in a quadriplegic patient with chronic enterocutaneous fistulas.
    Journal of pain & palliative care pharmacotherapy, 2012, Volume: 26, Issue:3

    Topics: Administration, Oral; Analgesics, Opioid; Benzodiazepines; Biological Availability; Chronic Disease; Chronic Pain; Humans; Intestinal Fistula; Male; Methadone; Morphine; Oxycodone; Quadriplegia; Young Adult

2012
The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.
    Forensic science international, 2013, Apr-10, Volume: 227, Issue:1-3

    Topics: Adult; Anesthetics, Local; Antitussive Agents; Bile; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Citalopram; Codeine; Dextromethorphan; Drug Contamination; Drug Overdose; Drug Users; Female; Forensic Pathology; Forensic Toxicology; Gastrointestinal Contents; Humans; Illicit Drugs; Kidney; Lidocaine; Liver; Lung; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Pyrrolidines; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Vitreous Body

2013
Different patterns of administration modulate propensity of methadone and buprenorphine to promote locomotor sensitization in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jan-10, Volume: 40

    Topics: Animals; Behavior, Animal; Buprenorphine; Drug Administration Schedule; Methadone; Mice; Morphine; Motor Activity; Narcotics

2013
Differential control of opioid antinociception to thermal stimuli in a knock-in mouse expressing regulator of G-protein signaling-insensitive Gαo protein.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Mar-06, Volume: 33, Issue:10

    Topics: Analgesics, Opioid; Animals; Brain; Diprenorphine; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Humans; Hyperalgesia; Inhibitory Postsynaptic Potentials; Isotopes; Male; Methadone; Mice; Mice, Transgenic; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Pain Measurement; Patch-Clamp Techniques; Pertussis Toxin; Protein Binding; Reaction Time; RGS Proteins; Signal Transduction; Spinal Cord

2013
The poor use of methadone in Italian hospices.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013, Volume: 21, Issue:8

    Topics: Analgesics, Opioid; Attitude of Health Personnel; Data Collection; Home Care Services; Hospice Care; Hospices; Humans; Italy; Methadone; Morphine; Pain; Palliative Care; Practice Patterns, Physicians'; Terminally Ill

2013
Development of sensitization to methamphetamine in offspring prenatally exposed to morphine, methadone and buprenorphine.
    Addiction biology, 2014, Volume: 19, Issue:4

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Buprenorphine; Central Nervous System Stimulants; Female; Male; Methadone; Methamphetamine; Models, Animal; Morphine; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger

2014
Pharmacogenetics of opiates in clinical practice: the visible tip of the iceberg.
    Pharmacogenomics, 2013, Volume: 14, Issue:5

    Topics: Analgesics, Opioid; Genetic Association Studies; Humans; Methadone; Morphine; Opioid Peptides; Pain Management; Pharmacogenetics; Receptors, Opioid; Receptors, Opioid, mu

2013
Comparison of the transcriptional responses induced by acute morphine, methadone and buprenorphine.
    European journal of pharmacology, 2013, Jul-05, Volume: 711, Issue:1-3

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Buprenorphine; Enkephalins; Male; Methadone; Morphine; Neostriatum; Nociceptin Receptor; Nucleus Accumbens; Pro-Opiomelanocortin; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid; RNA, Messenger; Thalamus; Transcription, Genetic

2013
Rotating to oral methadone in advanced cancer patients: a case series.
    Journal of palliative medicine, 2013, Volume: 16, Issue:9

    Topics: Adult; Aged; Analgesics, Opioid; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Methadone; Morphine; Neuralgia; Pain, Intractable; Prostatic Neoplasms; Uterine Cervical Neoplasms

2013
Dose ratios between high dose oral morphine or equivalents and oral methadone.
    Journal of palliative medicine, 2013, Volume: 16, Issue:8

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Hospice Care; Humans; Male; Medical Records; Methadone; Middle Aged; Morphine; New York; Pain Measurement; Pain, Intractable; Palliative Care; Retrospective Studies

2013
Potential P-glycoprotein pharmacokinetic interaction of telaprevir with morphine or methadone.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:3

    Topics: Analgesics, Opioid; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Overdose; Humans; Methadone; Morphine; Oligopeptides

2013
Methadone as an additional opioid for a cancer patient with severe neuropathic and bone pain not responsive to other opioids and adjuvant analgesics.
    Journal of palliative care, 2013,Summer, Volume: 29, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Drug Therapy, Combination; Humans; Lung Neoplasms; Methadone; Middle Aged; Morphine; Musculoskeletal Pain; Neuralgia; Palliative Care

2013
Challenges of treating patients with chronic pain with dysphagia (CPD): physician and patient perspectives.
    Current medical research and opinion, 2014, Volume: 30, Issue:2

    Topics: Analgesics, Opioid; Child; Chronic Pain; Data Collection; Deglutition Disorders; Fentanyl; Humans; Male; Medication Adherence; Methadone; Morphine; Palliative Care; Patient Medication Knowledge; Physicians; Treatment Outcome

2014
Safety profile of intravenous patient-controlled analgesia for breakthrough pain in cancer patients: a case series study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014, Volume: 22, Issue:3

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Breakthrough Pain; Constipation; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Nausea; Neoplasms; Pain Measurement; Retrospective Studies

2014
Conditioned rewarding effects of morphine and methadone in mice pre-exposed to cocaine.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:5

    Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Motivation; Reward; Time Factors

2013
[No opiates against cannabis hyperemesis syndrome].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:8

    Topics: Adult; Antiemetics; Dronabinol; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Germany; Humans; Infusions, Intravenous; Male; Marijuana Abuse; Methadone; Morphine; Opioid-Related Disorders; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Vomiting

2014
What is your gut feeling about opioid rotation?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jan-20, Volume: 33, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Biological Availability; Delayed-Action Preparations; Drug Administration Schedule; Fentanyl; Humans; Hydromorphone; Intestinal Obstruction; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Pain Management; Quality of Life

2015
A preliminary evaluation of the effects of opioids on innate and adaptive human in vitro immune function.
    BMJ supportive & palliative care, 2014, Volume: 4, Issue:4

    Topics: Adaptive Immunity; Adult; Analgesics, Opioid; Buprenorphine; Codeine; Fentanyl; Humans; Immunity, Innate; Interleukin-2; Interleukin-6; Leukocytes, Mononuclear; Methadone; Monocytes; Morphine; Neutrophils; Oxycodone; Phagocytosis; Respiratory Burst; Tramadol

2014
Comprehensive automation of the solid phase extraction gas chromatographic mass spectrometric analysis (SPE-GC/MS) of opioids, cocaine, and metabolites from serum and other matrices.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:18

    Topics: Acetamides; Analgesics, Opioid; Automation; Cocaine; Codeine; Flunitrazepam; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Robotics; Solid Phase Extraction; Substance Abuse Detection; Trimethylsilyl Compounds

2014
A study on photodegradation of methadone, EDDP, and other drugs of abuse in hair exposed to controlled UVB radiation.
    Drug testing and analysis, 2014, Volume: 6 Suppl 1

    Topics: Analgesics, Opioid; Cocaine; Hair; Humans; Methadone; Morphine; Morphine Derivatives; Photolysis; Pyrrolidines; Substance Abuse Detection; Ultraviolet Rays

2014
Simultaneous determination of drugs of abuse and their main metabolites using pressurized liquid extraction and liquid chromatography-tandem mass spectrometry.
    Talanta, 2014, Volume: 125

    Topics: Calibration; Chromatography, Liquid; Cocaine; Codeine; Methadone; Morphine; Reproducibility of Results; Sewage; Solvents; Spectrometry, Mass, Electrospray Ionization; Substance-Related Disorders; Tandem Mass Spectrometry; Temperature; Water Pollutants, Chemical

2014
Assessment of CYP450 genetic variability effect on methadone dose and tolerance.
    Pharmacogenomics, 2014, Volume: 15, Issue:7

    Topics: Adult; Alleles; Analgesics, Opioid; Biomarkers, Pharmacological; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Tolerance; Female; Heroin Dependence; Humans; International Normalized Ratio; Male; Methadone; Middle Aged; Morphine; Polymorphism, Single Nucleotide

2014
Characteristics and quality of life of opioid-dependent pregnant women in Austria.
    Archives of women's mental health, 2014, Volume: 17, Issue:6

    Topics: Administration, Oral; Adult; Austria; Buprenorphine; Delayed-Action Preparations; Female; Humans; Methadone; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Third; Pregnant Women; Quality of Life; Treatment Outcome

2014
A multicenter cohort study of treatments and hospital outcomes in neonatal abstinence syndrome.
    Pediatrics, 2014, Volume: 134, Issue:2

    Topics: Adult; Clinical Protocols; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intention to Treat Analysis; Length of Stay; Male; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Phenobarbital; Treatment Outcome; Young Adult

2014
Analysis of drugs of abuse in human plasma by dispersive liquid-liquid microextraction and high-performance liquid chromatography.
    Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:4

    Topics: Analytic Sample Preparation Methods; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cocaine; Humans; Hydrogen-Ion Concentration; Illicit Drugs; Limit of Detection; Liquid Phase Microextraction; Methadone; Morphine; Morphine Derivatives; Opiate Substitution Treatment; Photometry; Reproducibility of Results; Solubility; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Substance-Related Disorders; Ultrasonics

2015
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
Discriminative stimulus effects of the novel imidazoline I₂ receptor ligand CR4056 in rats.
    Scientific reports, 2014, Oct-13, Volume: 4

    Topics: Animals; Benzofurans; Imidazoles; Imidazoline Receptors; Imidazolines; Male; Methadone; Morphine; Quinazolines; Rats

2014
Hyperalgesia and increased sevoflurane minimum alveolar concentration induced by opioids in the rat: a randomised experimental study.
    European journal of anaesthesiology, 2015, Volume: 32, Issue:4

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Behavior, Animal; Buprenorphine; Hyperalgesia; Ketamine; Male; Methadone; Methyl Ethers; Morphine; Nociception; Pain Threshold; Piperidines; Pulmonary Alveoli; Random Allocation; Rats, Wistar; Remifentanil; Sevoflurane

2015
The use of very-low-dose methadone and haloperidol for pain control in the hospital setting: a preliminary report.
    Journal of palliative medicine, 2015, Volume: 18, Issue:2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; California; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Male; Methadone; Middle Aged; Morphine; Pain; Pain Management; Palliative Care; Retrospective Studies

2015
Physiological and analgesic effects of continuous-rate infusion of morphine, butorphanol, tramadol or methadone in horses with lipopolysaccharide (LPS)-induced carpal synovitis.
    BMC veterinary research, 2014, Dec-21, Volume: 10

    Topics: Analgesia; Analgesics, Opioid; Animals; Butorphanol; Carpal Joints; Horse Diseases; Horses; Infusions, Intravenous; Lameness, Animal; Lipopolysaccharides; Methadone; Morphine; Synovitis; Tramadol

2014
Comparing treatment-seeking codeine users and strong opioid users: Findings from a novel case series.
    Drug and alcohol review, 2015, Volume: 34, Issue:3

    Topics: Adult; Codeine; Female; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Oxycodone; Patient Acceptance of Health Care; Retrospective Studies

2015
Application of drug testing using exhaled breath for compliance monitoring of drug addicts in treatment.
    Scandinavian journal of clinical and laboratory investigation, 2015, Volume: 75, Issue:2

    Topics: Adolescent; Adult; Aged; Amphetamines; Breath Tests; Buprenorphine; Cocaine; Drug Users; Exhalation; Female; Humans; Male; Methadone; Methamphetamine; Middle Aged; Morphine; Morphine Derivatives; Patient Compliance; Substance Abuse Detection; Young Adult

2015
Out-of-hospital mortality among patients receiving methadone for noncancer pain.
    JAMA internal medicine, 2015, Volume: 175, Issue:3

    Topics: Adult; Aged; Cohort Studies; Death, Sudden; Delayed-Action Preparations; Female; Humans; Male; Methadone; Middle Aged; Morphine; Pain Management; Retrospective Studies

2015
Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca²⁺]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity.
    Current HIV research, 2014, Volume: 12, Issue:6

    Topics: Buprenorphine; Calcium; Cell Survival; Cells, Cultured; Chemokines; Humans; Methadone; Morphine; Narcotic Antagonists; Narcotics; Neuroglia; Neurons; Reactive Oxygen Species; tat Gene Products, Human Immunodeficiency Virus

2014
Quantification of morphine, morphine 6-glucuronide, buprenorphine, and the enantiomers of methadone by enantioselective mass spectrometric chromatography in whole blood.
    Forensic science, medicine, and pathology, 2015, Volume: 11, Issue:2

    Topics: Buprenorphine; Chromatography, Liquid; Forensic Toxicology; Humans; Mass Spectrometry; Methadone; Molecular Structure; Morphine; Morphine Derivatives; Narcotics; Solid Phase Extraction; Stereoisomerism; Substance-Related Disorders

2015
Data triangulation in the context of opioids monitoring via wastewater analyses.
    Drug and alcohol dependence, 2015, Jun-01, Volume: 151

    Topics: Adult; Analgesics, Opioid; Drug Residues; Female; Heroin; Humans; Illicit Drugs; Male; Methadone; Monte Carlo Method; Morphine; Needle-Exchange Programs; Opiate Substitution Treatment; Registries; Substance-Related Disorders; Switzerland; Wastewater

2015
Does therapeutic use of tapentadol cause false-positive urine screens for methadone or opiates?
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:5

    Topics: Adult; Aged, 80 and over; Analgesics, Opioid; Chromatography, Gas; Chromatography, Liquid; False Positive Reactions; Female; Humans; Hydrocodone; Immunoenzyme Techniques; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Phenols; Predictive Value of Tests; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Tapentadol; Urinalysis

2015
Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study.
    BMJ (Clinical research ed.), 2015, May-14, Volume: 350

    Topics: Adolescent; Adult; Analgesics, Opioid; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Infant; Infant, Newborn; Medicaid; Methadone; Middle Aged; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Pain; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prescriptions; Risk Factors; Smoking; United States

2015
Chemokine IP-10 is correlated with cardiac responses and status of infection with HIV and HCV in methadone maintenance patients.
    International journal of cardiology, 2015, Sep-01, Volume: 194

    Topics: Adult; Chemokine CXCL10; Chemokines; Electrocardiography; Female; Hepatitis C; Heroin Dependence; HIV Infections; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Tachycardia; Tumor Necrosis Factor-alpha; Young Adult

2015
Mediation of opioid analgesia by a truncated 6-transmembrane GPCR.
    The Journal of clinical investigation, 2015, Jul-01, Volume: 125, Issue:7

    Topics: Alternative Splicing; Analgesics, Opioid; Animals; Exons; Gene Targeting; Methadone; Mice; Mice, Knockout; Morphine; Naltrexone; Pain; Peptide Fragments; Protein Structure, Tertiary; Receptors, Opioid, mu; Recombinant Proteins

2015
Opioid Overdose Deaths in the City and County of San Francisco: Prevalence, Distribution, and Disparities.
    Journal of urban health : bulletin of the New York Academy of Medicine, 2015, Volume: 92, Issue:4

    Topics: Adolescent; Adult; Aged; Black or African American; Cocaine; Drug Overdose; Female; Health Status Disparities; Humans; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Poverty Areas; Prevalence; San Francisco; Socioeconomic Factors; Young Adult

2015
Use of Very-Low-Dose Methadone and Haloperidol for Pain Control in Palliative Care Patients: Are the Sigma-1 Receptors Involved?
    Journal of palliative medicine, 2015, Volume: 18, Issue:8

    Topics: Analgesics, Opioid; Female; Haloperidol; Humans; Male; Methadone; Morphine; Pain; Pain Management; Palliative Care

2015
Contrasting cardiovascular properties of the µ-opioid agonists morphine and methadone in the rat.
    European journal of pharmacology, 2015, Sep-05, Volume: 762

    Topics: Animals; Arterial Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiovascular System; Electrocardiography; Heart Rate; Histamine H1 Antagonists; Histamine H2 Antagonists; Mesenteric Arteries; Methadone; Morphine; Rats; Receptors, Opioid, mu

2015
Ethanol Reversal of Tolerance to the Respiratory Depressant Effects of Morphine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:3

    Topics: Analgesics, Opioid; Animals; Brain; Buprenorphine; Central Nervous System Depressants; Corticosterone; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Exploratory Behavior; Hot Temperature; Male; Methadone; Mice; Morphine; Motor Activity; Nociceptive Pain; Pain Threshold; Plethysmography; Respiration; Respiratory System Agents; Tidal Volume

2016
Illicit Heroin and Methamphetamine Use among Methadone Maintenance Treatment Patients in Dehong Prefecture of Yunnan Province, China.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Adolescent; Adult; Aged; Amphetamine-Related Disorders; Analgesics, Opioid; China; Cross-Sectional Studies; Data Collection; Drug Users; Female; Heroin Dependence; Humans; Logistic Models; Male; Methadone; Methamphetamine; Middle Aged; Morphine; Multivariate Analysis; Opiate Substitution Treatment; Substance Abuse Detection; Young Adult

2015
Implementation of a Neonatal Abstinence Syndrome Weaning Protocol: A Multicenter Cohort Study.
    Pediatrics, 2015, Volume: 136, Issue:4

    Topics: Adult; Analgesics, Opioid; Clinical Protocols; Cohort Studies; Female; Humans; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Retrospective Studies

2015
Methadone Reverses Analgesic Tolerance Induced by Morphine Pretreatment.
    The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:7

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Down-Regulation; Drug Tolerance; Endocytosis; Male; Methadone; Mice; Morphine; Pain Measurement; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu

2016
Sustained release oral morphine as an alternative to methadone for the treatment of opioid-use disorder post Torsades de Pointes cardiac arrest.
    BMJ case reports, 2015, Sep-21, Volume: 2015

    Topics: Administration, Oral; Delayed-Action Preparations; Electrocardiography; Heart Arrest; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Torsades de Pointes

2015
Neonatal abstinence syndrome: use of clonazepam?
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Analgesics, Opioid; Buprenorphine; Female; Humans; Male; Methadone; Morphine; Neonatal Abstinence Syndrome

2015
Reply to 'Methadone versus morphine for treatment of neonatal abstinence syndrome: a prospective randomized clinical trial'.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Analgesics, Opioid; Buprenorphine; Female; Humans; Male; Methadone; Morphine; Neonatal Abstinence Syndrome

2015
Fatal poisoning among patients with drug addiction.
    Danish medical journal, 2015, Volume: 62, Issue:10

    Topics: Adolescent; Adult; Age Distribution; Analgesics, Opioid; Cause of Death; Denmark; Female; Forensic Medicine; Humans; Male; Methadone; Middle Aged; Morphine; Sex Distribution; Substance-Related Disorders; Young Adult

2015
Long-Acting Opioids for Treating Neonatal Abstinence Syndrome: A High Price for a Short Stay?
    JAMA, 2015, Nov-17, Volume: 314, Issue:19

    Topics: Analgesics, Opioid; Half-Life; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Ondansetron; Serotonin Antagonists

2015
Understanding Heroin Overdose: A Study of the Acute Respiratory Depressant Effects of Injected Pharmaceutical Heroin.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Capnography; Drug Overdose; Electromyography; Female; Heroin; Heroin Dependence; Humans; Hypoventilation; Injections, Intramuscular; Male; Methadone; Middle Aged; Morphine; Oximetry; Pulmonary Disease, Chronic Obstructive

2015
Retrospective chart review comparing morphine and methadone in neonates treated for neonatal abstinence syndrome.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Dec-01, Volume: 72, Issue:23 Suppl 3

    Topics: Administration, Oral; Analgesics, Opioid; Female; Humans; Infant, Newborn; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Retrospective Studies; Treatment Outcome

2015
Neonatal withdrawal syndrome and perinatal asphyxia. How to manage the patient? Case Report.
    Neuro endocrinology letters, 2015, Volume: 36 Suppl 1

    Topics: Asphyxia Neonatorum; Disease Management; Humans; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opiate Substitution Treatment

2015
Impact of blended treatment literacy and psychoeducation on methadone maintenance treatment outcomes in Yunnan, China.
    Harm reduction journal, 2016, Feb-26, Volume: 13

    Topics: Adult; China; Combined Modality Therapy; Female; Heroin Dependence; Humans; Male; Medication Adherence; Methadone; Middle Aged; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Education as Topic; Peer Group; Physicians; Treatment Outcome; Young Adult

2016
Expression levels of OPRM1 and PDYN in human SH-SY5Y cells treated with morphine and methadone.
    Life sciences, 2016, Apr-01, Volume: 150

    Topics: Analgesics, Opioid; Cell Line; Dose-Response Relationship, Drug; Enkephalins; Humans; Methadone; Morphine; Protein Precursors; Receptors, Opioid, mu; RNA, Messenger

2016
The ABCB1, rs9282564, AG and TT Genotypes and the COMT, rs4680, AA Genotype are Less Frequent in Deceased Patients with Opioid Addiction than in Living Patients with Opioid Addiction.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:4

    Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B; Catechol O-Methyltransferase; Cohort Studies; Death, Sudden; Denmark; Female; Genetic Association Studies; Heterozygote; Homozygote; Humans; Male; Methadone; Middle Aged; Morphine; Morphine Dependence; Narcotics; Polymorphism, Single Nucleotide; Young Adult

2016
The effect of chronic morphine or methadone exposure and withdrawal on clock gene expression in the rat suprachiasmatic nucleus and AA-NAT activity in the pineal gland.
    Physiological research, 2016, 07-18, Volume: 65, Issue:3

    Topics: Animals; Arginine Vasopressin; Circadian Rhythm; In Situ Hybridization; Male; Methadone; Morphine; Narcotics; Period Circadian Proteins; Rats, Wistar; Substance Withdrawal Syndrome; Suprachiasmatic Nucleus

2016
NICE calls for safer use of controlled drugs.
    BMJ (Clinical research ed.), 2016, Apr-13, Volume: 353

    Topics: Analgesics, Opioid; Benzodiazepines; Controlled Substances; Diazepam; Drug Storage; Humans; Methadone; Morphine; Patient Education as Topic

2016
Effect of breastfeeding on neonatal abstinence syndrome.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2016, Jun-15, Volume: 73, Issue:12

    Topics: Breast Feeding; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome

2016
Prescription of Long-Acting Opioids and Mortality in Patients With Chronic Noncancer Pain.
    JAMA, 2016, Jun-14, Volume: 315, Issue:22

    Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Cardiovascular Diseases; Cause of Death; Chronic Pain; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Oxycodone; Propensity Score; Proportional Hazards Models; Retrospective Studies; Risk

2016
Popliteal Vein Blood Sampling and the Postmortem Redistribution of Diazepam, Methadone, and Morphine.
    Journal of forensic sciences, 2016, Volume: 61, Issue:4

    Topics: Diazepam; Forensic Toxicology; Humans; Methadone; Morphine; Popliteal Vein; Postmortem Changes

2016
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
    Journal of analytical toxicology, 2016, Volume: 40, Issue:8

    Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine

2016
Evaluation of the vaginal flora in pregnant women receiving opioid maintenance therapy: a matched case-control study.
    BMC pregnancy and childbirth, 2016, 08-05, Volume: 16, Issue:1

    Topics: Adult; Analgesics, Opioid; Asymptomatic Infections; Austria; Birth Weight; Buprenorphine; Candidiasis, Vulvovaginal; Case-Control Studies; Female; Gestational Age; Humans; Infant, Newborn; Maintenance Chemotherapy; Methadone; Morphine; Opioid-Related Disorders; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Trichomonas Vaginitis; Vagina; Vaginosis, Bacterial; Young Adult

2016
Neonatal Abstinence Syndrome: Twelve Years of Experience at a Regional Referral Center.
    Klinische Padiatrie, 2017, Volume: 229, Issue:1

    Topics: Buprenorphine; Diseases in Twins; Female; Hospitalization; Humans; Infant, Newborn; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Pregnancy; Referral and Consultation; Retrospective Studies; Substance Abuse Treatment Centers; Treatment Outcome

2017
Growth hormone is protective against acute methadone-induced toxicity by modulating the NMDA receptor complex.
    Neuroscience, 2016, Dec-17, Volume: 339

    Topics: Animals; Caspase 3; Caspase 7; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Human Growth Hormone; L-Lactate Dehydrogenase; Methadone; Mitochondria; Morphine; Naloxone; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; RNA, Messenger

2016
Postmortem Concentration and Redistribution of Diazepam, Methadone, and Morphine with Subclavian and Femoral Vein Dissection/Clamping.
    Journal of forensic sciences, 2016, Volume: 61, Issue:6

    Topics: Constriction; Diazepam; Femoral Vein; Humans; Methadone; Morphine; Postmortem Changes

2016
The relationship between gestational age and the severity of neonatal abstinence syndrome.
    Addiction (Abingdon, England), 2017, Volume: 112, Issue:4

    Topics: Adult; Analgesics, Opioid; Female; Gestational Age; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Length of Stay; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Ohio; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Premature Birth; Retrospective Studies; Severity of Illness Index; Term Birth; Time Factors; Young Adult

2017
Site-, Technique-, and Time-Related Aspects of the Postmortem Redistribution of Diazepam, Methadone, Morphine, and their Metabolites: Interest of Popliteal Vein Blood Sampling.
    Journal of forensic sciences, 2017, Volume: 62, Issue:6

    Topics: Adult; Blood Specimen Collection; Chromatography, Liquid; Diazepam; Female; Femoral Vein; Forensic Toxicology; Humans; Male; Methadone; Middle Aged; Morphine; Morphine Derivatives; Nordazepam; Oxazepam; Popliteal Vein; Postmortem Changes; Subclavian Vein; Young Adult

2017
Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1.
    Molecular psychiatry, 2017, Volume: 22, Issue:3

    Topics: Adult; Alleles; Analgesics, Opioid; Black or African American; Dose-Response Relationship, Drug; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Pain; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; United States; White People

2017
Evaluation of an Automated Reader and Color Interpretation-Based Immunoassays for Multiplexed Drug-of-Abuse Testing in Urine.
    Journal of analytical toxicology, 2017, Jun-01, Volume: 41, Issue:5

    Topics: Amphetamine; Automation; Buprenorphine; China; Cocaine; Dronabinol; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Immunoassay; Mass Spectrometry; Methadone; Methamphetamine; Morphine; Sensitivity and Specificity; Substance Abuse Detection

2017
Commentary on Gibson et al. (2017): Gestational age and the severity of neonatal abstinence syndrome.
    Addiction (Abingdon, England), 2017, Volume: 112, Issue:4

    Topics: Buprenorphine; Gestational Age; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy Complications

2017
Comparison Between Urinalysis Results and Self-Reported Heroin Use Among Patients Undergoing Methadone Maintenance Treatment in China.
    Substance use & misuse, 2017, 08-24, Volume: 52, Issue:10

    Topics: Adult; China; Depression; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Reproducibility of Results; Self Efficacy; Self Report; Substance Abuse Detection; Young Adult

2017
Pharmacogenomics study on cadherin 2 network with regard to HIV infection and methadone treatment outcome.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: ADAM10 Protein; Adult; Amyloid Precursor Protein Secretases; Antigens, CD; Cadherins; Female; Heroin; Heroin Dependence; HIV Infections; Humans; Interleukin-7; Male; Membrane Proteins; Methadone; Morphine; Pharmacogenetics; Polymorphism, Single Nucleotide; Treatment Outcome; Vitamin D

2017
Sex Differences in Regional Brain Glucose Metabolism Following Opioid Withdrawal and Replacement.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:9

    Topics: Analgesics, Opioid; Animals; Brain; Brain Mapping; Buprenorphine; Cross-Sectional Studies; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Glucose; Longitudinal Studies; Male; Methadone; Morphine; Morphine Dependence; Positron-Emission Tomography; Radiopharmaceuticals; Rats, Sprague-Dawley; Sex Characteristics; Treatment Outcome

2017
An Initiative to Improve the Quality of Care of Infants With Neonatal Abstinence Syndrome.
    Pediatrics, 2017, Volume: 139, Issue:6

    Topics: Female; Hospital Costs; Humans; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Quality Indicators, Health Care; Quality of Health Care

2017
Chemical stability of morphine and methadone, and of methadone in combination with acepromazine, medetomidine or xylazine, during prolonged storage in syringes.
    Australian veterinary journal, 2017, Volume: 95, Issue:8

    Topics: Acepromazine; Animals; Drug Stability; Drug Storage; Medetomidine; Methadone; Morphine; Syringes; Xylazine

2017
The Effect of Morphine Dosing on Length of Stay in Neonatal Abstinence Syndrome - An Alternative Viewpoint.
    Pharmacotherapy, 2017, Volume: 37, Issue:11

    Topics: Hospitals, Community; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome

2017
Comparison of Neonatal Abstinence Syndrome Treatment with Sublingual Buprenorphine versus Conventional Opioids.
    American journal of perinatology, 2018, Volume: 35, Issue:4

    Topics: Analgesics, Opioid; Buprenorphine; Drug Administration Schedule; Female; Humans; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Retrospective Studies; Time Factors

2018
Interpretation of Urine Drug Screens: Metabolites and Impurities.
    JAMA, 2017, Nov-07, Volume: 318, Issue:17

    Topics: Analgesics, Opioid; Codeine; False Positive Reactions; Female; Humans; Hydromorphone; Immunoassay; Mass Spectrometry; Methadone; Middle Aged; Morphine; Substance Abuse Detection

2017
Missense mutation at CLDN8 associated with a high plasma interferon gamma-inducible protein 10 level in methadone-maintained patients with urine test positive for morphine.
    PloS one, 2017, Volume: 12, Issue:11

    Topics: Adult; Chemokine CXCL10; Claudins; Female; Humans; Male; Methadone; Morphine; Mutation, Missense; Opiate Substitution Treatment; Substance Abuse Detection

2017
APBB2 is associated with amphetamine use and plasma beta-amyloids in patients receiving methadone maintenance treatment.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 04-20, Volume: 83

    Topics: Adaptor Proteins, Signal Transducing; Adult; Amphetamine-Related Disorders; Amyloid beta-Peptides; Biomarkers; Cells, Cultured; Female; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Interferon-gamma; Lymphocytes; Male; Methadone; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Peptide Fragments; Polymorphism, Single Nucleotide; Promoter Regions, Genetic

2018
Patterns of regional variation of opioid prescribing in primary care in England: a retrospective observational study.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2018, Volume: 68, Issue:668

    Topics: Analgesics, Opioid; Buprenorphine; Chronic Pain; Crime; Databases, Factual; Education; Employment; England; Health Status; Housing; Humans; Income; Methadone; Morphine; Oxycodone; Practice Patterns, Physicians'; Primary Health Care; Residence Characteristics; Retrospective Studies; Socioeconomic Factors; Tramadol

2018
Disulfiram attenuates morphine or methadone withdrawal syndrome in mice.
    Behavioural pharmacology, 2018, Volume: 29, Issue:5

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Disulfiram; Male; Methadone; Mice; Mice, Inbred C57BL; Models, Animal; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome

2018
Effects of dexmedetomidine combined with commonly administered opioids on clinical variables in dogs.
    American journal of veterinary research, 2018, Volume: 79, Issue:3

    Topics: Analgesics, Opioid; Animals; Butorphanol; Dexmedetomidine; Dogs; Drug Combinations; Female; Heart Rate; Male; Methadone; Morphine; Respiratory Rate; Tramadol

2018
Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose.
    Pain medicine (Malden, Mass.), 2019, 01-01, Volume: 20, Issue:1

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Drug Tolerance; Female; Humans; Hyperalgesia; Injections, Intravenous; Male; Methadone; Morphine; Opiate Substitution Treatment; Pain Measurement; Pain Threshold; Young Adult

2019
The effect of standardizing treatment when managing neonatal abstinence syndrome
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019, Volume: 32, Issue:20

    Topics: Adolescent; Adult; Analgesics, Opioid; Clinical Protocols; Comorbidity; Female; Humans; Infant; Infant, Newborn; Length of Stay; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Reference Standards; Treatment Outcome; Young Adult

2019
Treadmill exercise attenuates the severity of physical dependence, anxiety, depressive-like behavior and voluntary morphine consumption in morphine withdrawn rats receiving methadone maintenance treatment.
    Neuroscience letters, 2018, 08-10, Volume: 681

    Topics: Animals; Anxiety; Depression; Exercise Test; Male; Maze Learning; Methadone; Morphine; Morphine Dependence; Opiate Substitution Treatment; Physical Conditioning, Animal; Rats; Self Administration; Severity of Illness Index; Substance Withdrawal Syndrome

2018
Effects of treadmill exercise on methadone withdrawal-induced locomotor sensitization and the ventral pallidum and ventral tegmental area BDNF levels in morphine withdrawn rats receiving methadone maintenance treatment.
    Neuroscience letters, 2018, 09-14, Volume: 683

    Topics: Analgesics, Opioid; Animals; Basal Forebrain; Brain-Derived Neurotrophic Factor; Exercise Test; Locomotion; Male; Methadone; Morphine; Morphine Dependence; Opiate Substitution Treatment; Rats; Rats, Sprague-Dawley; Rats, Wistar; Treatment Outcome; Ventral Tegmental Area

2018
Profile, risk practices and needs of people who inject morphine sulfate: Results from the ANRS-AERLI study.
    The International journal on drug policy, 2018, Volume: 59

    Topics: Adult; Buprenorphine; Female; France; Humans; Longitudinal Studies; Male; Methadone; Morphine; Narcotics; Needs Assessment; Opiate Substitution Treatment; Substance Abuse, Intravenous

2018
In vitro evaluation of effects of metformin on morphine and methadone tolerance through mammalian target of rapamycin signaling pathway.
    Journal of cellular physiology, 2019, Volume: 234, Issue:3

    Topics: AMP-Activated Protein Kinase Kinases; Analgesics, Opioid; Animals; Cell Line, Tumor; Cyclic AMP; Drug Tolerance; Eukaryotic Initiation Factors; Glioblastoma; Humans; Metformin; Methadone; Morphine; Opioid-Related Disorders; Phosphorylation; Protein Kinases; Pyrazoles; Pyrimidines; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases

2019
One size does not fit all-evolution of opioid agonist treatments in a naturalistic setting over 23 years.
    Addiction (Abingdon, England), 2019, Volume: 114, Issue:1

    Topics: Adult; Age Factors; Analgesics, Opioid; Buprenorphine; Employment; Family Relations; Female; Friends; Heroin; Housing; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Social Integration; Social Participation; Substance Abuse, Intravenous; Switzerland

2019
Morphine vs Methadone Treatment for Infants with Neonatal Abstinence Syndrome.
    The Journal of pediatrics, 2018, Volume: 203

    Topics: Cohort Studies; Databases, Factual; Female; Follow-Up Studies; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Length of Stay; Male; Methadone; Morphine; Multivariate Analysis; Neonatal Abstinence Syndrome; Propensity Score; Retrospective Studies; Risk Assessment; Treatment Outcome; United States

2018
Long-acting Opioid Use and the Risk of Serious Infections: A Retrospective Cohort Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 05-17, Volume: 68, Issue:11

    Topics: Adult; Aged; Analgesics, Opioid; Chronic Pain; Female; Fentanyl; Hospitalization; Humans; Immunosuppressive Agents; Infections; Male; Medicaid; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Retrospective Studies; Risk Factors; Tennessee; United States

2019
Evaluation of an on-site test device for the heroin metabolite 6-acetylmorphine in urine.
    Drug testing and analysis, 2019, Volume: 11, Issue:3

    Topics: Buprenorphine; Codeine; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Methadone; Morphine; Morphine Derivatives; Reagent Strips; Sensitivity and Specificity; Substance Abuse Detection

2019
Morphine, but not methadone, inhibits microsomal prostaglandin E synthase-1 and prostaglandin-endoperoxide synthase 2 in lipopolysaccharide-stimulated horse synoviocytes.
    Biochimie, 2019, Volume: 160

    Topics: Analgesics, Opioid; Animals; Cells, Cultured; Cyclooxygenase 2; Gene Expression Regulation, Enzymologic; Horses; Inflammation; Lipopolysaccharides; Male; Methadone; Microsomes; Morphine; Prostaglandin-E Synthases; Synoviocytes

2019
Suppression of Human Natural Killer Cells by Different Classes of Opioids.
    Anesthesia and analgesia, 2019, Volume: 128, Issue:5

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Anesthesia; Buprenorphine; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Fluoresceins; Humans; Immunosuppression Therapy; K562 Cells; Killer Cells, Natural; Loperamide; Methadone; Morphinans; Morphine; Naloxone; Naltrexone; Succinimides; Toll-Like Receptor 4; Tramadol

2019
Role of agonist efficacy in exposure-induced enhancement of mu opioid reward in rats.
    Neuropharmacology, 2019, Volume: 151

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Dose-Response Relationship, Drug; Fentanyl; Male; Methadone; Morphine; Nalbuphine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Self Stimulation

2019
Opioid-galanin receptor heteromers mediate the dopaminergic effects of opioids.
    The Journal of clinical investigation, 2019, 03-26, Volume: 129, Issue:7

    Topics: Analgesics, Opioid; Animals; Cell Line; Humans; Male; Methadone; Morphine; Protein Multimerization; Rats; Rats, Sprague-Dawley; Receptor, Galanin, Type 1; Receptors, Opioid, mu

2019
Morphine infusor pump switch to oral methadone.
    BMJ supportive & palliative care, 2020, Volume: 10, Issue:1

    Topics: Administration, Oral; Aged; Analgesics, Opioid; Cancer Pain; Dose-Response Relationship, Drug; Drug Substitution; Fatal Outcome; Female; Humans; Infusion Pumps; Infusions, Subcutaneous; Male; Methadone; Middle Aged; Morphine; Palliative Care; Spain

2020
Current Status of Adverse Events Related with Opioid Analgesics in Japan: Assessment Based on Japanese Adverse Drug Event Report Database.
    Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Databases, Factual; Fentanyl; Humans; Japan; Methadone; Morphine; Oxycodone; Tapentadol

2019
Concomitant Heroin and Cocaine Use among Opioid-Dependent Patients during Methadone, Buprenorphine or Morphine Opioid Agonist Therapy.
    European addiction research, 2019, Volume: 25, Issue:4

    Topics: Adult; Analgesics, Opioid; Behavior, Addictive; Buprenorphine; Cocaine; Cross-Sectional Studies; Delayed-Action Preparations; Female; Heroin; Humans; Male; Methadone; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Switzerland

2019
Placental trophoblast transfer of opioids following exposures to individual or mixtures of opioids
    Experimental biology and medicine (Maywood, N.J.), 2019, Volume: 244, Issue:10

    Topics: Analgesics, Opioid; Female; Fentanyl; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Maternal-Fetal Exchange; Methadone; Morphine; Naloxone; Oxycodone; Placenta; Pregnancy; Trophoblasts

2019
Opioid-galanin receptor heteromers differentiate the dopaminergic effects of morphine and methadone.
    The Journal of clinical investigation, 2019, 05-28, Volume: 129, Issue:7

    Topics: Analgesics, Opioid; Animals; Dopamine Agents; Galanin; Methadone; Morphine; Rats; Receptors, Galanin; Receptors, Opioid; Receptors, Opioid, mu

2019
Morphine vs methadone in the treatment of neonatal abstinence syndrome.
    Acta paediatrica (Oslo, Norway : 1992), 2019, Volume: 108, Issue:9

    Topics: Humans; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders

2019
Interventions for the Treatment of Neonatal Abstinence Syndrome.
    Nursing for women's health, 2019, Volume: 23, Issue:4

    Topics: Analgesics, Opioid; Buprenorphine; Female; Humans; Infant, Newborn; Male; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Pregnancy; Pregnancy Complications; Treatment Outcome

2019
Opioid receptor-mediated changes in the NMDA receptor in developing rat and chicken.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2019, Volume: 78

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Cerebellum; Chickens; Female; Methadone; Morphine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2019
Risk assessment of using off-label morphine sulfate in a population-based retrospective cohort of opioid-dependent patients.
    British journal of clinical pharmacology, 2020, Volume: 86, Issue:12

    Topics: Analgesics, Opioid; Buprenorphine; Delivery of Health Care; Humans; Male; Methadone; Morphine; Off-Label Use; Opiate Substitution Treatment; Opioid-Related Disorders; Retrospective Studies; Risk Assessment

2020
Management of Newborns with Prenatal Opioid Exposure: One Institution's Journey.
    Clinical therapeutics, 2019, Volume: 41, Issue:9

    Topics: Analgesics, Opioid; Female; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Outpatients; Parents; Pregnancy; Quality Improvement

2019
Correlation between interleukin-6 levels and methadone maintenance therapy outcomes.
    Drug and alcohol dependence, 2019, 11-01, Volume: 204

    Topics: Adolescent; Adult; Aged; Biomarkers; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Female; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Transforming Growth Factor beta1; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult

2019
The place of methadone in the Game of the Goose for postoperative pain.
    Minerva anestesiologica, 2019, Volume: 85, Issue:10

    Topics: Analgesics, Opioid; Animals; Geese; Humans; Methadone; Morphine; Pain, Postoperative

2019
Comparison of pre-pulse inhibition, tactile discrimination learning and barrel cortical neural response in adult male rats following chronic exposure to morphine, methadone and buprenorphine.
    Physiology & behavior, 2019, 12-01, Volume: 212

    Topics: Animals; Auditory Perception; Buprenorphine; Cerebral Cortex; Discrimination Learning; Male; Methadone; Morphine; Neurons; Prepulse Inhibition; Rats; Stereotyped Behavior; Touch Perception

2019
Characteristics and circumstances of heroin and pharmaceutical opioid overdose deaths: Comparison across opioids.
    Drug and alcohol dependence, 2019, 12-01, Volume: 205

    Topics: Adolescent; Adult; Analgesics, Opioid; Australia; Chronic Pain; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Naloxone; Opioid-Related Disorders; Tramadol; Young Adult

2019
Long-time effects of prenatal morphine, tramadol, methadone, and buprenorphine exposure on seizure and anxiety in immature rats.
    The International journal of neuroscience, 2020, Volume: 130, Issue:9

    Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Buprenorphine; Female; Locomotion; Male; Maze Learning; Methadone; Morphine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Seizures; Sex Factors; Tramadol

2020
Neonatal Abstinence Syndrome.
    Pediatric annals, 2020, Jan-01, Volume: 49, Issue:1

    Topics: History, 19th Century; History, 20th Century; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; United States

2020
Stereoselective Analysis of Methadone and EDDP in Laboring Women and Neonates in Plasma and Dried Blood Spots and Association with Neonatal Abstinence Syndrome.
    American journal of perinatology, 2021, Volume: 38, Issue:9

    Topics: Analgesics, Opioid; Anticonvulsants; Dried Blood Spot Testing; Female; Humans; Infant, Newborn; Labor, Obstetric; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Pyrrolidines

2021
Emerging therapies for the treatment of neonatal abstinence syndrome.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:5

    Topics: Analgesics, Opioid; Buprenorphine; Female; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy

2022
The impact of the prescription opioid epidemic on young children: Trends and mortality.
    Drug and alcohol dependence, 2020, 06-01, Volume: 211

    Topics: Analgesics, Opioid; Buprenorphine; Child, Preschool; Epidemics; Female; Fentanyl; Humans; Infant; Male; Methadone; Morphine; Opioid Epidemic; Oxycodone; Poison Control Centers; Prescription Drugs

2020
Enriched Environment Ameliorates Cognitive Deficits and Locomotor Sensitization in Morphine-Withdrawn Rats Receiving Methadone Maintenance Treatment.
    Neuropsychobiology, 2020, Volume: 79, Issue:6

    Topics: Animals; Cognitive Dysfunction; Locomotion; Male; Methadone; Morphine; Narcotics; Opiate Substitution Treatment; Rats; Rats, Wistar; Recognition, Psychology; Spatial Learning; Substance Withdrawal Syndrome

2020
Methadone rotation for cancer pain: an observational study.
    BMJ supportive & palliative care, 2022, Volume: 12, Issue:e6

    Topics: Analgesics, Opioid; Cancer Pain; Humans; Methadone; Morphine; Neoplasms; Neuralgia

2022
Postmortem metabolomics: Correlating time-dependent concentration changes of xenobiotic and endogenous compounds.
    Drug testing and analysis, 2020, Volume: 12, Issue:8

    Topics: Adult; Aged; Autopsy; Chromatography, Liquid; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolomics; Methadone; Middle Aged; Morphine; Postmortem Changes; Reproducibility of Results; Time Factors; Xenobiotics; Young Adult

2020
Clonidine versus phenobarbital as adjunctive therapy for neonatal abstinence syndrome.
    Journal of perinatology : official journal of the California Perinatal Association, 2020, Volume: 40, Issue:7

    Topics: Analgesics, Opioid; Clonidine; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Prospective Studies

2020
Switching opioid-dependent patients in substitution treatment from racemic methadone, levomethadone and buprenorphine to slow-release oral morphine: Analysis of the switching process in routine care.
    Journal of pharmacological sciences, 2020, Volume: 144, Issue:1

    Topics: Administration, Oral; Adult; Buprenorphine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Substitution; Female; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Treatment Outcome; Young Adult

2020
Effects of polysubstance exposure on neonatal outcomes for infants with intrauterine opioid exposure.
    Journal of perinatology : official journal of the California Perinatal Association, 2020, Volume: 40, Issue:10

    Topics: Analgesics, Opioid; Female; Humans; Infant; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Pregnancy; Retrospective Studies

2020
Glutathione and Glutathione-Like Sequences of Opioid and Aminergic Receptors Bind Ascorbic Acid, Adrenergic and Opioid Drugs Mediating Antioxidant Function: Relevance for Anesthesia and Abuse.
    International journal of molecular sciences, 2020, Aug-28, Volume: 21, Issue:17

    Topics: Analgesics, Opioid; Ascorbic Acid; Dehydroascorbic Acid; Enkephalin, Methionine; Glutathione; Humans; Hydromorphone; Methadone; Morphine; Naloxone; Peptides; Receptors, Adrenergic, beta-2; Receptors, Dopamine D1; Receptors, Histamine H1; Receptors, Opioid; Receptors, Opioid, mu

2020
Revealing the Kinetic Advantage of a Competitive Small-Molecule Immunoassay by Direct Detection.
    Analytical chemistry, 2020, 10-06, Volume: 92, Issue:19

    Topics: Antibodies; Binding, Competitive; Cocaine; Immunoassay; Kinetics; Methadone; Morphine; Small Molecule Libraries

2020
Lithium reverses the effect of opioids on eNOS/nitric oxide pathway in human umbilical vein endothelial cells.
    Molecular biology reports, 2020, Volume: 47, Issue:9

    Topics: Analgesics, Opioid; Cell Survival; Cyclic AMP; Drug Tolerance; Glycogen Synthase Kinase 3 beta; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Lithium Chloride; Methadone; Morphine; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Signal Transduction

2020
Orchestrated Testing of Formula Type to Reduce Length of Stay in Neonatal Abstinence Syndrome.
    Pediatrics, 2020, Volume: 146, Issue:4

    Topics: Energy Intake; Female; Humans; Infant Formula; Infant, Newborn; Lactose; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Ohio; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Quality Improvement; Weight Gain

2020
Aspiration in lethal drug abuse-a consequence of opioid intoxication.
    International journal of legal medicine, 2020, Volume: 134, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Austria; Autopsy; Cause of Death; Female; Forensic Toxicology; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Respiratory Aspiration of Gastric Contents; Retrospective Studies; Substance-Related Disorders; Young Adult

2020
Model-Based Approach to Improve Clinical Outcomes in Neonates With Opioid Withdrawal Syndrome Using Real-World Data.
    Clinical pharmacology and therapeutics, 2021, Volume: 109, Issue:1

    Topics: Analgesics, Opioid; Electronic Health Records; Female; Hospitalization; Humans; Infant, Newborn; Length of Stay; Longitudinal Studies; Male; Methadone; Morphine; Retrospective Studies; Substance Withdrawal Syndrome

2021
Methadone-mediated sensitization of glioblastoma cells is drug and cell line dependent.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:3

    Topics: Analgesics, Opioid; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Glioblastoma; Humans; Methadone; Morphine; Naloxone; Oxycodone; Receptors, Opioid, mu; Tumor Cells, Cultured

2021
Is Maternal Methadone Dose Associated with the Severity of Neonatal Abstinence Syndrome?
    American journal of perinatology, 2022, Volume: 39, Issue:10

    Topics: Female; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Pregnancy; Retrospective Studies

2022
The effects of morphine, methadone, and fentanyl on mitochondria: A live cell imaging study.
    Brain research bulletin, 2021, Volume: 171

    Topics: Animals; Cell Line, Tumor; Fentanyl; Methadone; Mice; Mitochondria; Morphine; Narcotics; Rats; Time-Lapse Imaging

2021
Is it time to replace morphine with methadone for the treatment of pain in the neonatal intensive care unit?
    Pediatric research, 2021, Volume: 89, Issue:7

    Topics: Analgesics, Opioid; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Methadone; Morphine; Pain Management

2021
Substitution treatment for opioid dependence with slow-release oral morphine: Retention rate, health status, and substance use after switching to morphine.
    Journal of substance abuse treatment, 2021, Volume: 127

    Topics: Adult; Analgesics, Opioid; Delayed-Action Preparations; Germany; Health Status; Humans; Male; Methadone; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Prospective Studies; Treatment Outcome

2021
Dental Plaque Concentrations of Methadone, Morphine and Their Metabolites in Opioid Replacement Therapy and in Postmortem Cases.
    Journal of analytical toxicology, 2022, Jul-14, Volume: 46, Issue:6

    Topics: Dental Plaque; Humans; Methadone; Morphine; Opiate Substitution Treatment; Pyrrolidines; Substance-Related Disorders

2022
Hydromorphone and codeine concentrations in oral fluid specimens from patients receiving substitution therapy with Substitol™ (morphine sulfate).
    Drug testing and analysis, 2021, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Buprenorphine; Codeine; Female; Humans; Hydromorphone; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Saliva; Substance Abuse Detection

2021
Uptake of slow-release oral morphine as opioid agonist treatment among hospitalised patients with opioid use disorder.
    Drug and alcohol review, 2022, Volume: 41, Issue:2

    Topics: Analgesics, Opioid; Buprenorphine; Humans; Methadone; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders

2022
Buprenorphine Increases HIV-1 Infection In Vitro but Does Not Reactivate HIV-1 from Latency.
    Viruses, 2021, 07-27, Volume: 13, Issue:8

    Topics: Buprenorphine; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Methadone; Morphine; Nociceptin Receptor; Receptors, Opioid; Virus Activation; Virus Latency; Virus Replication

2021
Declines and regional variation in opioid distribution by U.S. hospitals.
    Pain, 2022, 06-01, Volume: 163, Issue:6

    Topics: Analgesics, Opioid; Buprenorphine; Codeine; Hospitals; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Oxymorphone; United States

2022
Morphine dependence and withdrawal-induced changes in mouse Sertoli cell (TM4) line: Evaluation of apoptotic, inflammatory and oxidative stress biomarkers.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 105

    Topics: Analgesics, Opioid; Animals; Apoptosis; Biomarkers; Cell Line; Cyclic AMP; Glial Cell Line-Derived Neurotrophic Factor; Inflammation; Male; Methadone; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Oxidative Stress; Oxidoreductases; Proto-Oncogene Proteins c-bcl-2; Sertoli Cells; Substance Withdrawal Syndrome

2021
Effect of Methadone Maintenance on Expression of BDNF and CREB Genes in Brain VTA of Male Morphine Treated Rats.
    Central nervous system agents in medicinal chemistry, 2021, Volume: 21, Issue:3

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Male; Methadone; Morphine; Rats; Rats, Wistar

2021
Opioid Weaning Protocol Using Morphine Compared With Nonprotocolized Methadone Associated With Decreased Dose and Duration of Opioid After Norwood Procedure.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2022, 05-01, Volume: 23, Issue:5

    Topics: Analgesics, Opioid; Child; Humans; Infant, Newborn; Methadone; Morphine; Norwood Procedures; Substance Withdrawal Syndrome

2022
Morphine to methadone, and beyond.
    Anaesthesia and intensive care, 2022, Volume: 50, Issue:1-2

    Topics: Humans; Methadone; Morphine

2022
Intraoperative Methadone Use in Pediatric Burn Patients.
    Journal of burn care & research : official publication of the American Burn Association, 2022, 11-02, Volume: 43, Issue:6

    Topics: Adult; Analgesics, Opioid; Burns; Child; Humans; Methadone; Morphine; Pain; Retrospective Studies

2022
Neonatal Opioid Withdrawal Syndrome: A Comparison of As-Needed Pharmacotherapy.
    Hospital pediatrics, 2022, 05-01, Volume: 12, Issue:5

    Topics: Analgesics, Opioid; Female; Humans; Infant; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Pregnancy; Retrospective Studies

2022
    Central nervous system agents in medicinal chemistry, 2022, Volume: 22, Issue:2

    Topics: Analgesics, Opioid; Humans; Methadone; Morphine; Neuroblastoma

2022
Simultaneous electrochemical determination of morphine and methadone by using CMK-5 mesoporous carbon and multivariate calibration.
    Scientific reports, 2022, 05-18, Volume: 12, Issue:1

    Topics: Calibration; Carbon; Electrochemical Techniques; Electrodes; Limit of Detection; Methadone; Morphine

2022
REL-1017 (esmethadone; D-methadone) does not cause reinforcing effect, physical dependence and withdrawal signs in Sprague Dawley rats.
    Scientific reports, 2022, 07-06, Volume: 12, Issue:1

    Topics: Animals; Ketamine; Methadone; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Substance-Related Disorders

2022
Common opioids and stimulants in autopsy and DUID cases: A comparison of measured concentrations.
    Forensic science international, 2022, Volume: 338

    Topics: Amphetamine; Analgesics, Opioid; Autopsy; Central Nervous System Stimulants; Cocaine; Coma; Heroin; Humans; Methadone; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Substance-Related Disorders

2022
Characteristics of Prescription Opioid Analgesics in Pregnancy and Risk of Neonatal Opioid Withdrawal Syndrome in Newborns.
    JAMA network open, 2022, 08-01, Volume: 5, Issue:8

    Topics: Adult; Analgesics, Opioid; Codeine; Cohort Studies; Female; Humans; Hydrocodone; Hydromorphone; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Morphine; Neonatal Abstinence Syndrome; Oxycodone; Pain; Pregnancy; Prescriptions; Substance Withdrawal Syndrome; Tramadol; United States

2022
Combined effects of quetiapine and opioids: A study of autopsy cases, drug users and sedation in rats.
    Addiction biology, 2022, Volume: 27, Issue:5

    Topics: Analgesics, Opioid; Animals; Autopsy; Drug Users; Humans; Hypnotics and Sedatives; Methadone; Morphine; Quetiapine Fumarate; Rats

2022
Opioid replacement therapy with methadone or buprenorphine effects on male mice reproduction.
    Psychopharmacology, 2023, Volume: 240, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Chromatin; Male; Methadone; Mice; Morphine; Morphine Dependence; Opiate Substitution Treatment; Opioid-Related Disorders; Reproduction; Semen; Semen Analysis

2023
Commentary on Nikoo et al.: Challenges in protocol development to optimize outcomes of opium tincture maintenance treatment.
    Addiction (Abingdon, England), 2023, Volume: 118, Issue:2

    Topics: Humans; Methadone; Morphine; Opium; Research Design

2023
Letter-to-the-editor, concerning the article entitled "Common opioids and stimulants in autopsy and DUID cases: A comparison of measured concentrations."
    Forensic science international, 2023, Volume: 344

    Topics: Amphetamine; Analgesics, Opioid; Autopsy; Central Nervous System Stimulants; Cocaine; Methadone; Morphine; Substance Abuse Detection

2023
Single-Center Retrospective Comparison of Opioid-Based and Multimodal Analgesic Regimens in Adult Cardiac Surgery.
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:7

    Topics: Adult; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Dexmedetomidine; Humans; Methadone; Morphine; Opioid-Related Disorders; Pain, Postoperative; Postoperative Nausea and Vomiting; Retrospective Studies

2023
Validation of an HPLC-HR-MS Method for the Determination and Quantification of Six Drugs (Morphine, Codeine, Methadone, Alprazolam, Clonazepam and Quetiapine) in Nails.
    Journal of analytical toxicology, 2023, May-19, Volume: 47, Issue:5

    Topics: Alprazolam; Benzodiazepines; Chromatography, High Pressure Liquid; Clonazepam; Codeine; Humans; Methadone; Morphine; Nails; Quetiapine Fumarate

2023
Rescue Analgesia for Opioid-Dependent Individuals on Opioid Agonist Treatment during Hospitalization: Adherence to Guideline Treatment.
    European addiction research, 2023, Volume: 29, Issue:4

    Topics: Adult; Analgesics; Analgesics, Opioid; Female; Hospitalization; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Pain; Pain Management

2023
Detection of Three Opioids (Morphine, Codeine and Methadone) and Their Metabolites (6-Monoacetylmorphine and 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) in Larvae of
    Molecules (Basel, Switzerland), 2023, Jun-08, Volume: 28, Issue:12

    Topics: Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Codeine; Diptera; Humans; Larva; Methadone; Morphine; Morphine Derivatives

2023
Assessing the impact of the slow-release oral morphine drug shortages in Ontario, Canada: A population-based time series analysis.
    The International journal on drug policy, 2023, Volume: 118

    Topics: Administration, Oral; Analgesics, Opioid; Delayed-Action Preparations; Female; Humans; Male; Methadone; Morphine; Ontario; Opiate Substitution Treatment; Opioid-Related Disorders; Pain; Retrospective Studies; Time Factors

2023
Comparison of oral versus intravenous methadone on postoperative pain and opioid use after adult spinal deformity surgery: A retrospective, non-inferiority analysis.
    PloS one, 2023, Volume: 18, Issue:7

    Topics: Adult; Analgesics, Opioid; Cohort Studies; Humans; Long QT Syndrome; Methadone; Morphine; Opioid-Related Disorders; Pain, Postoperative; Retrospective Studies

2023
Assessment of the potential of novel and classical opioids to induce respiratory depression in mice.
    British journal of pharmacology, 2023, Volume: 180, Issue:24

    Topics: Analgesics, Opioid; Animals; HEK293 Cells; Humans; Male; Methadone; Mice; Morphine; Oxycodone; Respiratory Insufficiency

2023
Shift in hospital opioid use during the COVID-19 pandemic in Brazil: a time-series analysis of one million prescriptions.
    Scientific reports, 2023, 10-11, Volume: 13, Issue:1

    Topics: Adult; Analgesics, Opioid; Brazil; COVID-19; Fentanyl; Humans; Methadone; Morphine; Opioid-Related Disorders; Pandemics; Prescriptions; Remifentanil; Sufentanil; Tramadol

2023
Distribution of morphine and methadone to the brain in a developmental chicken embryo model.
    Toxicology and applied pharmacology, 2023, Nov-15, Volume: 479

    Topics: Analgesics, Opioid; Animals; Brain; Chick Embryo; Chickens; Chromatography, Liquid; Drug Tolerance; Female; Humans; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Pregnancy; Receptors, Opioid, mu; Tandem Mass Spectrometry

2023
A comparison of meconium, maternal urine and neonatal urine for detection of maternal drug use during pregnancy.
    Journal of forensic sciences, 1994, Volume: 39, Issue:1

    Topics: Adult; Cocaine; Dronabinol; Female; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Infant, Newborn; Meconium; Methadone; Narcotics; New York City; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prevalence; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders

1994
Neonatal hair analysis contribution to establishing a gestational drug exposure profile and predicting a withdrawal syndrome.
    Therapeutic drug monitoring, 2003, Volume: 25, Issue:4

    Topics: Cannabinoids; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant, Newborn; Meconium; Methadone; Narcotics; Neonatal Abstinence Syndrome; Pregnancy; Substance Abuse Detection

2003
Determination of methadone, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, 2-ethyl-5-methyl-3,3-diphenylpyraline and methadol in meconium by liquid chromatography atmospheric pressure chemical ionization tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Jan-25, Volume: 814, Issue:2

    Topics: Atmospheric Pressure; Humans; Mass Spectrometry; Meconium; Methadone; Pyrrolidines; Reproducibility of Results; Sensitivity and Specificity

2005
Comparison of drugs of abuse detection in meconium by EMIT II and ELISA.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:3

    Topics: Amphetamines; Analgesics, Opioid; Barbiturates; Benzodiazepines; Cannabinoids; Chromatography, Liquid; Cocaine; Dextropropoxyphene; Enzyme Multiplied Immunoassay Technique; Enzyme-Linked Immunosorbent Assay; False Positive Reactions; Female; Fetus; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Methadone; Phencyclidine Abuse; Pregnancy; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry

2009
Prenatal methadone exposure, meconium biomarker concentrations and neonatal abstinence syndrome.
    Addiction (Abingdon, England), 2010, Volume: 105, Issue:12

    Topics: Adult; Analgesics, Opioid; Cocaine; Cocaine-Related Disorders; Female; Gestational Age; Humans; Infant, Newborn; Length of Stay; Meconium; Methadone; Narcotics; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Predictive Value of Tests; Pregnancy; Pregnancy Complications; Premature Birth; Prenatal Exposure Delayed Effects; Prospective Studies; Substance Abuse Detection; Young Adult

2010
Alternative matrices for cocaine, heroin, and methadone in utero drug exposure detection.
    Therapeutic drug monitoring, 2013, Volume: 35, Issue:4

    Topics: Chromatography, Liquid; Cocaine; Drug Monitoring; Female; Hair; Heroin; Humans; Maternal-Fetal Exchange; Meconium; Methadone; Placenta; Pregnancy; Substance Abuse Detection; Tandem Mass Spectrometry; Umbilical Cord; Uterus

2013
Rates of fetal polydrug exposures in methadone-maintained pregnancies from a high-risk population.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Adult; Cocaine; Female; Humans; Infant, Newborn; Meconium; Methadone; Opiate Substitution Treatment; Pregnancy

2013
Bioanalysis for cocaine, opiates, methadone, and amphetamines exposure detection during pregnancy.
    Drug testing and analysis, 2017, Volume: 9, Issue:6

    Topics: Amphetamines; Analgesics, Opioid; Anesthetics, Local; Central Nervous System Stimulants; Cocaine; Female; Hair; Humans; Infant, Newborn; Meconium; Methadone; Opiate Alkaloids; Pregnancy; Substance Abuse Detection; Tandem Mass Spectrometry; Umbilical Cord

2017
Screening for Opioid and Stimulant Exposure In Utero Through Targeted and Untargeted Metabolomics Analysis of Umbilical Cords.
    Therapeutic drug monitoring, 2020, Volume: 42, Issue:5

    Topics: Analgesics, Opioid; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Female; Humans; Meconium; Metabolomics; Methadone; Neonatal Abstinence Syndrome; Pregnancy; Prospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Umbilical Cord

2020