methadone has been researched along with meperidine in 234 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 195 (83.33) | 18.7374 |
| 1990's | 18 (7.69) | 18.2507 |
| 2000's | 10 (4.27) | 29.6817 |
| 2010's | 9 (3.85) | 24.3611 |
| 2020's | 2 (0.85) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Bodinier, MC; Bonnet, B; Chapelain, B; Déprez, B; Eckhoff, C; Horvath, D; Poulain, R | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mehta, VL | 1 |
| McIndewar, I; Sugrue, MF | 1 |
| Oka, T; Sawa, A | 1 |
| Blundell, C; Slater, P | 1 |
| Dvorchik, BH; Hartman, RD; Stenger, VG | 1 |
| Bergmann, F; Chaimovitz, M; Pasternak, V | 1 |
| Hosoya, K; Oka, T | 1 |
| Oka, T | 1 |
| Dewey, WL; Forbes, JE | 1 |
| Gianutsos, G; Lal, H; Puri, SK | 1 |
| Kreek, MJ; Oratz, M; Rothschild, MA | 1 |
| Lumb, WV; Pippi, NL | 1 |
| Cheung, S; Sancilio, LF | 1 |
| Muir, WW; Sheehan, WC; Skarda, RT | 1 |
| Leander, JD; McMillan, DE | 1 |
| Gibson, TC | 1 |
| Deacon, MA; Iorio, LC; Ryan, EA | 1 |
| Alkadhi, KA; Hogan, YH | 1 |
| Jiang, Z | 1 |
| Ennis, M; Lorenz, W; Nehring, E; Schneider, C | 1 |
| Bundgaard, H; Christrup, L; Fullerton, A | 1 |
| Kaa, E | 1 |
| Dickenson, AH; McQuay, HJ; Smallman, K; Sullivan, AF | 1 |
| Koren, G; Maurice, L | 1 |
| Kaa, E; Steentoft, A; Worm, K | 1 |
| Deshpande, JK; Maxwell, LG; Yaster, M | 1 |
| Carino, MA; Horita, A; Yamawaki, S | 1 |
| Hyttel, J; Larsen, JJ | 1 |
| Chiang, CN; Lee, CC | 1 |
| Wood, M | 1 |
| Clarke, KW; Paton, BS | 1 |
| Frank, GB; Shetty, SS | 2 |
| Paule, MG; Wenger, GR | 1 |
| Coyle, DE; Denson, DD | 1 |
| Babbini, M; Bacchi, A; Bartoletti, M; Gaiardi, M; Gubellini, C | 1 |
| Bowman, ER; Brase, DA; Dewey, WL; Kachur, JF; Martin, BR; Rosemond, R; Welch, S | 1 |
| Gorodetzky, CW | 1 |
| Eddy, NB; May, EL | 1 |
| Baden, MM; Huang, JC | 1 |
| Terenius, L | 1 |
| Kreuzer, H; Spiller, P | 1 |
| Caldwell, J; Sever, PS | 1 |
| Brister, CC; Davis, WM | 2 |
| Prianishnikova, NT; Raevskii, KS | 2 |
| Elliott, HW; Hine, CH; Nomof, N; Parker, KD | 1 |
| Juvara, I; Radulesco, D | 1 |
| Fujimoto, JM; Wang, RI | 1 |
| Gourley, DR | 1 |
| Stockhaus, K; Wick, H | 2 |
| Ahtee, L; Jounela, AJ; Saarnivaara, L; Simola, I | 1 |
| Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A | 1 |
| Contreras, E; Huidobro, F | 1 |
| Collier, HO; Roy, AC | 1 |
| Casy, AF; Hassan, MM | 1 |
| Bauer, G; Konzett, H; Ziegler, E | 1 |
| Beckett, AH; Triggs, EJ | 1 |
| Julich, H | 1 |
| Carlsson, A; Lindqvist, M | 1 |
| Eddy, NB; Friebel, H; Hahn, KJ; Halbach, H | 1 |
| Beattie, JM; Demetriou, JA; Lowe, ML; Weissman, N | 1 |
| Andryauskas, S; Broich, JR; Goldner, SJ; Hoffman, DB; Umberger, CJ | 1 |
| Bowman, WC; Buwembo, JB | 1 |
| Higgins, TN; Taylor, JD | 1 |
| Goodlet, I; Sugrue, MF | 2 |
| Capetola, RJ; Gero, A | 1 |
| Teiger, DG | 1 |
| Kaneto, H; Koida, M; Nakanishi, H | 1 |
| Kaneto, H; Koida, M; Nakanishi, H; Sasano, H | 1 |
| Vandam, LD | 1 |
| Stetson, JB | 1 |
| Fernandes, M | 1 |
| Carmichael, FJ; Israel, Y | 1 |
| Colasanti, B; Khazan, N | 1 |
| Babbini, M; Bartoletti, M; Gaiardi, M | 1 |
| Granat, FR; Saelens, JK | 1 |
| Andersen Lund, BM; Ellekjaer, EF | 1 |
| Ghezzi, D; Mauron, C; Samanin, R; Valzelli, L | 1 |
| Montel, H; Starke, K | 1 |
| Fjalland, B; Lassen, N; Nielsen, IM; Pedersen, V; Petersen, PV | 1 |
| Gorodetzky, CW; Kullberg, MP | 1 |
| Biemann, K; Costello, CE; Hertz, HS; Sakai, T | 1 |
| Burke, DH; Mann, DE | 1 |
| Holder, AT; Robinson, AE | 1 |
| Misra, AL | 1 |
| Dundee, JW; Jones, PO | 1 |
| Cushman, P | 1 |
| Ho, IK; Loh, HH; Way, EL | 1 |
| Huidobro, F | 1 |
| Dickson, DN | 1 |
| Jhamandas, K; Phillis, JW; Pinsky, C | 1 |
| Campbell, DB; Ramsey, J | 1 |
| Gozon, F | 1 |
| Marshall, I; Weinstock, M | 1 |
| Dundee, JW; Loan, WB; Morrison, JD | 1 |
| Molinengo, L; Ricci-Gamalero, S | 2 |
| Bendick, F; Greenwald, W; Short, CE | 1 |
| Lorenzetti, OJ; Sancilio, LF | 1 |
| Langrod, J | 1 |
| Kamei, C; Kaneto, H; Nakanishi, H; Shimomura, K | 1 |
| Elliott, HW | 1 |
| Vallvé, C | 1 |
| Blumberg, AG; Heaton, AM | 1 |
| McMartin, C; Simpson, P; Thorpe, N | 1 |
| Benzi, G; Berté, F; Crema, A; Frigo, GM | 1 |
| Chernov, HI; Grumbach, L | 1 |
| Burks, TF; Long, JP | 1 |
| Blane, GF | 1 |
| Contreras, E; Quijada, L; Tamayo, L | 1 |
| Noess, K | 1 |
| Amsterdam, EA; Henderson, GL; Mason, DT; Rendig, SV | 1 |
| Pybus, DA; Torda, TA | 1 |
| Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE | 1 |
| Tenenbein, M | 1 |
| Jacobson, AE | 1 |
| Leander, JD | 1 |
| Davies, JV; Gerring, EL | 1 |
| Beleslin, DB; Krstić, SK; Stefanović-Denić, K | 1 |
| Tung, AS; Yaksh, TL | 1 |
| Davis, WM; Hemnani, KL; Pace, HB | 1 |
| Beleslin, DB; Krstić, SK; Mićić, D; Stefanović-Denić, K; Strbac, M | 1 |
| Andersen, S; Ebert, B; Krogsgaard-Larsen, P | 1 |
| Jensen, NH; Jensen, TS; Sjøgren, P | 1 |
| Henry, JA; Wu, C | 1 |
| Kaa, E; Kringsholm, B; Simonsen, KW; Steentoft, A; Worm, K | 1 |
| Kaa, E; Teige, B | 1 |
| Hamunen, K | 1 |
| Borgbjerg, FM; Eriksen, J; Groth Clausen, T | 1 |
| Clausen, TG | 1 |
| Alvarez Requejo, A; Caro-Patón, T; Carvajal, A; García del Pozo, J; Martín Arias, LH; Martín de Diego, I; Rueda, AM | 1 |
| Andersen, S; Christrup, LL; Ebert, B; Hjeds, H; Thorkildsen, C | 1 |
| Cano del Pozo, MI; Carvajal, A; García del Pozo, J; Martín Arias, LH; Rueda de Castro, AM | 1 |
| Kim, M; Kim, S; Kim, TJ; Lee, JC; Myung, SW; Park, JH | 1 |
| Berbatis, CG; Bulsara, M; Lintzeris, N; Sunderland, VB | 1 |
| Ho, TS; Pedersen-Bjergaard, S; Rasmussen, KE | 1 |
| WILBRANDT, W | 1 |
| LONGO, VG; NAPOLITANO, L | 1 |
| MAY, EL | 1 |
| ISBELL, H; WHITE, WM | 1 |
| VOGEL, G | 1 |
| BRANDSTATTER, M | 1 |
| BAIN, JA; WANG, RI | 1 |
| CARRATALA, R; COSENTINO, R; COSTA, AJ | 1 |
| SANTARATO, R | 1 |
| BODMAN, RI | 1 |
| BRAENDEN, OJ; WOLFF, PO | 1 |
| MILOSEVIC, MP | 2 |
| ANGIBEAUD, P; BUCHEL, L; LEVY, J | 1 |
| FAUCETT, RL | 1 |
| PATON, WD | 1 |
| HADICKE, M; KUNTZE, M | 1 |
| JAGENEAU, AH; JANSSEN, PA | 1 |
| LYNCH, TA; MEYERS, DB | 1 |
| HADICKE, M; POETHKE, W; WIGERT, R | 2 |
| GREEN, AF | 1 |
| COLLIER, HO; SKERRY, R; WARNER, BT | 1 |
| JACOB, J; MICHAUD, G | 2 |
| REKKER, RF; van der POL, H | 1 |
| RUTSCHMANN, T | 1 |
| TAKEMORI, AE | 2 |
| LAJOIE, WJ | 1 |
| PARIS, J; U BOIS, R; VANDENDORP, F | 1 |
| JOHNSON, CA; KING, RE | 1 |
| JACOBSEN, FG; SCHAFII-LASCHTENESCHAI, AH; ZETLER, G | 1 |
| COLLINS, RJ; MACGREGOR, DW; WEEKS, JR | 1 |
| THOMPSON, WL; WALTON, RP | 1 |
| MATTS, SG | 1 |
| MEYERSTEIN, AN | 1 |
| WANG, RI | 1 |
| KOERNER, M | 1 |
| WEEKS, JR | 1 |
| STEWART, GA; YOUNG, PA | 1 |
| CHAPPEL, CI; VONSEEMANN, C | 1 |
| HAMBURGER, E | 1 |
| LASAGNA, L | 1 |
| LARSON, DL; PORTOGHESE, PS | 1 |
| COX, BM; WEINSTOCK, M | 1 |
| SHEMANO, I; WENDEL, H | 1 |
| KRUG, DC; PATRICK, SW; ROSENTHAL, T | 1 |
| KOSTERLITZ, HW; WALLIS, DI | 1 |
| PESCE, A; RUGIERO, G | 1 |
| BOLDINO, G | 1 |
| BURKHALTER, A; KUPFERBERG, HJ; WAY, EL | 1 |
| ABDEL-RAHMAN, MA; ELLIOTT, HW | 1 |
| CLARK, JP | 1 |
| ANDERSON, RC; EMMERSON, JL | 1 |
| HORAKOVA, Z; VOTAVA, Z | 1 |
| Dagenais, C; Graff, CL; Pollack, GM | 1 |
| SALTER, WT | 1 |
| STREETEN, DH; WILLAMS, EM | 1 |
| BENNETT, DR; HENDERSHOT, LC; HOUDE, RW; IRWIN, S; SEEVERS, MH | 1 |
| PETERSEN, PV | 1 |
| VIDIC, E | 1 |
| ENGELHARDT, H; KEWITZ, H; REMMER, H | 1 |
| Carrougher, GJ; Engrav, LH; Friedrich, JB; Gibran, NS; Heckbert, SR; Heimbach, DM; Honari, S; Klein, MB; Lezotte, DC; Round, KA; Sullivan, SR; Wiechman, SA | 1 |
| STEELE, CW | 1 |
| WOLFF, PO | 1 |
| GRUBER, CM; LEE, KS | 1 |
| BUCHANAN, OH; TAINTER, ML | 1 |
| WATTS, DT | 1 |
| Stewart, HC; Weinstock, M | 1 |
| TAINTER, ML | 1 |
| CHRISTENSEN, EM; GROSS, EG | 1 |
| JOHNSON, HT; SHIDEMAN, FE | 2 |
| ELLIOTT, HW; JAMES, HP; WARRENS, AE | 1 |
| Kolesnikov, YA; Oksman, G; Pasternak, GW | 1 |
| Cai, Z; Chen, G; Lai, Y; Li, Q; Lu, M; Qiu, B; Zhang, L | 1 |
| Hendrickson, RG; McKeown, NJ | 1 |
| Flø, L; Hansen, SH; Janfelt, C; Pedersen-Bjergaard, S; Thunig, J | 1 |
| Hansen, SH; Jensen, H; Li, B; Payán, MD; Pedersen-Bjergaard, S; Petersen, NJ | 1 |
| Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M | 1 |
| ElSohly, MA; Godfrey, M; Gul, SW; Gul, W; Stamper, B | 1 |
| Eidbo, SA; Hagedorn, JD; Kaufman, DE; Kropp Lopez, AK; Mathew, V; McCall, KL; Nichols, SD; Piper, BJ | 1 |
| Bellocchi, F; Bufalari, A; Giannettoni, G; Menchetti, L; Moretti, G; Nannarone, S; Pepe, A | 1 |
15 review(s) available for methadone and meperidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Cholinergic mechanisms in narcotic analgesics.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Brain Chemistry; Cats; Chlorpromazine; Choline; Meperidine; Methadone; Morphine; Nalorphine; Neurons; Neurotransmitter Agents; Parasympathetic Nervous System; Time Factors | 1975 |
The heart in myasthenia gravis.
Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans; Lidocaine; Meperidine; Methadone; Morphine; Myasthenia Gravis; Myocarditis; Myocardium; Neuromuscular Junction; Phenytoin; Procaine; Quinidine; Vectorcardiography | 1975 |
Pediatric uses of opioids.
Topics: Child; Child, Preschool; Codeine; Drug Interactions; Fentanyl; Humans; Infant; Infant, Newborn; Meperidine; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Pediatrics; Receptors, Opioid | 1989 |
The pharmacologic management of pain in children.
Topics: Analgesia, Epidural; Analgesics; Child; Child, Preschool; Codeine; Fentanyl; Humans; Infant; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Pain | 1989 |
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors | 1986 |
The biochemical pharmacology of abused drugs. III. Cannabis, opiates, and synthetic narcotics.
Topics: Animals; Cannabis; Chemical Phenomena; Chemistry; Columbidae; Cricetinae; Dronabinol; Drug Tolerance; Half-Life; Humans; Memory, Short-Term; Meperidine; Methadone; Microsomes, Liver; Morphine; Narcotics; Neurotransmitter Agents; Opium; Pentazocine; Perception; Rats; Substance-Related Disorders; Synaptic Transmission; Teratogens | 1974 |
Hypothesis: Inhibition of E prostaglandin-sensitive adenyl cyclase as the mechanism of morphine analgesia.
Topics: Adenylyl Cyclases; Animals; Aspirin; Brain; Cyclic AMP; Depression, Chemical; Fluorides; Guinea Pigs; Heroin; In Vitro Techniques; Levorphanol; Meperidine; Methadone; Mice; Morphinans; Morphine; Naloxone; Prostaglandin Antagonists; Prostaglandins; Rabbits; Rats; Receptors, Drug; Sodium; Stimulation, Chemical | 1974 |
Codeine and its alternates for pain and cough relief . 4. Potential alternates for cough relief.
Topics: Alkaloids; Animals; Antitussive Agents; Cats; Codeine; Cough; Dogs; Guinea Pigs; Histamine H1 Antagonists; Humans; Isoquinolines; Meperidine; Methadone; Mice; Morphinans; Phenanthrenes; Phenothiazines; Rats; Substance-Related Disorders | 1969 |
Drug therapy: analgetic drugs--the potent analgetics.
Topics: Analgesics; Blood Circulation; Fentanyl; Humans; Intestines; Levallorphan; Meperidine; Methadone; Methotrimeprazine; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Nausea; Pain; Pentazocine; Psychopharmacology; Respiration; Substance-Related Disorders; Urinary Tract; Vomiting | 1972 |
Opioid analgesics as noncompetitive N-methyl-D-aspartate (NMDA) antagonists.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Dextropropoxyphene; Excitatory Amino Acid Antagonists; Humans; Meperidine; Methadone; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1998 |
DRUG ADDICTION: A REVIEW.
Topics: Adolescent; Amphetamine; Amphetamines; Barbiturates; Cannabis; Codeine; Heroin; Humans; Hydromorphone; Jurisprudence; Meperidine; Mescaline; Methadone; Morphine Dependence; Nalorphine; Narcotic Antagonists; Psychotherapy; Statistics as Topic; Substance-Related Disorders | 1964 |
ANTITUSSIVE DRUGS.
Topics: Antipsychotic Agents; Antitussive Agents; Chemistry, Pharmaceutical; Codeine; Cough; Dextromoramide; Drug Therapy; Humans; Meperidine; Methadone; Morphine; Pharmacology; Phenothiazines; Phenylacetates; Piperazines; Piperidines; Research; Thiophenes | 1963 |
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Meperidine; Methadone; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Oxymorphone; Pentazocine; Phenazocine; Substance-Related Disorders; Toxicology | 1964 |
ANALGESICS FOR USE IN DENTAL PRACTICE.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Azepines; Codeine; Dentistry; Dextropropoxyphene; Drug Therapy; Meperidine; Methadone; Phenacetin | 1965 |
4 trial(s) available for methadone and meperidine
| Article | Year |
|---|---|
The clinical testing of weak oral analgesics.
Topics: Administration, Oral; Analgesics; Clinical Trials as Topic; Drug Evaluation; Humans; Meperidine; Methadone; Methods; Naphthaleneacetic Acids; Pain; Time Factors | 1974 |
The prevention of analgesic-induced nausea and vomiting by cyclizine.
Topics: Analgesia; Clinical Trials as Topic; Codeine; Cyclizine; Female; Humans; Levorphanol; Male; Meperidine; Methadone; Nausea; Placebos; Vomiting | 1968 |
Comparison of four narcotic analgesics for extradural analgesia.
Topics: Adult; Aged; Analgesics, Opioid; Epidural Space; Female; Fentanyl; Hemodynamics; Humans; Injections; Male; Meperidine; Methadone; Middle Aged; Morphine; Pain, Postoperative; Respiration; Time Factors | 1982 |
Ventilatory effects of morphine, pethidine and methadone in children.
Topics: Child; Child, Preschool; Depression, Chemical; Female; Humans; Male; Meperidine; Methadone; Morphine; Oxygen; Pain, Postoperative; Respiration; Tidal Volume; Time Factors | 1993 |
215 other study(ies) available for methadone and meperidine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
From hit to lead. Combining two complementary methods for focused library design. Application to mu opiate ligands.
Topics: Animals; Cerebral Cortex; Combinatorial Chemistry Techniques; Humans; Imidazoles; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Radioligand Assay; Rats; Receptors, Opioid, mu; Solubility; Spiro Compounds; Structure-Activity Relationship | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of blockade of 5-hydroxytryptamine re-uptake on drug-induced antinociception in the rat.
Topics: Analgesics; Animals; Brain; Depression, Chemical; Male; Meperidine; Methadone; Morphine; Phenyl Ethers; Propylamines; Rats; Reaction Time; Serotonin | 1976 |
Effects of narcotic analgesics on serotonin metabolism in brain of rats and mice.
Topics: Analgesics, Opioid; Animals; Atropine; Brain; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Mice; Mice, Inbred ICR; Morphine; Naloxone; Pargyline; Probenecid; Rats; Serotonin | 1976 |
The effect of 6-hydroxydopamine on the antinociceptive action of analgesics in mice.
Topics: Analgesics, Opioid; Animals; Drug Interactions; Female; Hydroxydopamines; Injections, Intraventricular; Levorphanol; Meperidine; Methadone; Mice; Morphine; Pentazocine; Reaction Time; Time Factors | 1977 |
Drug metabolism by the fetal stump-tailed monkey (Macaca arctoides). Hepatic microsomal N-demethylation and glucuronidation as measured by radiometric assays.
Topics: Animals; Animals, Newborn; Cytochrome P-450 Enzyme System; Gestational Age; Glucuronidase; Haplorhini; Liver; Macaca; Meperidine; Methadone; Microsomes, Liver; Morphine; Organ Size; Oxidoreductases, N-Demethylating; Proteins | 1979 |
Dual action of morphine and related drugs on compulsive gnawing of rats.
Topics: Animals; Apomorphine; Behavior, Animal; Compulsive Behavior; Female; Fenclonine; Humans; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Stereotyped Behavior; Thalamic Nuclei | 1976 |
The effect of p-chlorophenylalanine on the pethidine- or methadone-induced decrease in locomotor activity of rats.
Topics: Animals; Depression, Chemical; Fenclonine; Male; Meperidine; Methadone; Motor Activity; Rats; Time Factors | 1976 |
Role of 5-hydroxytryptamine in morphine-, pethidine-, and methadone-induced hypothermia in rats at low ambient and room temperature.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Cold Temperature; Depression, Chemical; Drug Interactions; Fenclonine; Male; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Temperature; Time Factors | 1977 |
The effects of narcotic analgesics and narcotic antagonists on ganglionic transmission in the rat.
Topics: Animals; Ganglia, Autonomic; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Stereoisomerism; Synaptic Transmission | 1976 |
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Dexetimide; Dextromoramide; Dogs; Dopamine; Drug Combinations; Haloperidol; Humans; Meperidine; Methadone; Mice; Morphine; Phenoperidine; Pimozide; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome; Tranquilizing Agents; Vomiting | 1975 |
Hepatic extraction of long- and short-acting narcotics in the isolated perfused rabbit liver.
Topics: Animals; Biotransformation; Heroin; Liver; Liver Circulation; Meperidine; Methadone; Morphine; Narcotics; Rabbits; Time Factors | 1978 |
Objective tests of analgesic drugs in ponies.
Topics: Analgesics; Animals; Disease Models, Animal; Female; Fentanyl; Horse Diseases; Horses; Male; Meperidine; Methadone; Oxymorphone; Pain; Pentazocine; Xylazine | 1979 |
Analysis of the bradykinin response in dogs and its antagonism by analgesic drugs.
Topics: Analgesics; Animals; Aspirin; Bradykinin; Dextroamphetamine; Dogs; Dose-Response Relationship, Drug; Female; Indomethacin; Male; Meperidine; Methadone; Phenylbutazone | 1978 |
Cardiopulmonary effects of narcotic agonists and a partial agonist in horses.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Carotid Arteries; Heart Rate; Horses; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pentazocine; Respiration | 1978 |
Meperidine effects on schedule-controlled responding.
Topics: Animals; Columbidae; Conditioning, Operant; Cyclazocine; Drug Interactions; Drug Tolerance; Male; Meperidine; Methadone; Morphine; Naloxone; Reaction Time; Reinforcement Schedule | 1977 |
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Injections, Intraperitoneal; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotics; Pentazocine; Substance Withdrawal Syndrome | 1975 |
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on ganglionic transmission.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Electric Stimulation; Ganglia, Sympathetic; In Vitro Techniques; Male; Meperidine; Methadone; Morphine; Naloxone; Rats; Rats, Inbred Strains; Synaptic Transmission | 1992 |
[Iatrogenic addiction of pethidine: clinical feature and experience of detoxification].
Topics: Adult; Clonidine; Female; Humans; Iatrogenic Disease; Male; Meperidine; Methadone; Substance-Related Disorders | 1992 |
Histamine release induced by opioid analgesics: a comparative study using porcine mast cells.
Topics: Analgesics, Opioid; Animals; Histamine Release; Hydromorphone; Kidney; Liver; Lung; Mast Cells; Meperidine; Methadone; Morphine; Myocardium; Oxycodone; Swine | 1991 |
Evaluation of the transdermal route for administration of narcotic analgesics: human skin permeability studies of methadone and pethidine.
Topics: Administration, Cutaneous; Humans; Meperidine; Methadone; Skin Absorption | 1991 |
[Narcotic abuse in Jylland. A study based on narcotics and deaths of addicts examined at the Institute of Forensic Medicine, University of Aarhus during the period 1981-1988. 2. Deaths among addicts].
Topics: Adolescent; Adult; Alcoholic Intoxication; Amphetamine; Denmark; Dextropropoxyphene; Female; Heroin Dependence; Humans; Male; Meperidine; Methadone; Middle Aged; Opioid-Related Disorders; Substance-Related Disorders | 1990 |
Intrathecal opioids, potency and lipophilicity.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Endorphins; Injections, Spinal; Membrane Lipids; Meperidine; Methadone; Morphine; Morphine Derivatives; Nociceptors; Rats; Receptors, Opioid; Receptors, Opioid, mu; Solubility; Spinal Cord | 1989 |
Fatal intoxications in the age group 15-34 years in Denmark in 1984 and 1985. A forensic study with special reference to drug addicts.
Topics: Adolescent; Adult; Analgesics, Opioid; Barbiturates; Cause of Death; Cross-Sectional Studies; Denmark; Dextropropoxyphene; Drug Overdose; Heroin; Humans; Incidence; Meperidine; Methadone; Morphine; Substance-Related Disorders | 1989 |
Analeptic effect of opiate receptor agonists in rabbits.
Topics: Animals; Arousal; Brain; Central Nervous System Stimulants; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethylketocyclazocine; Etorphine; Male; Meperidine; Methadone; Morphine; Naltrexone; Narcotics; Phenazocine; Rabbits; Receptors, Opioid; Reflex | 1985 |
5-HT-uptake inhibition potentiates antinociception induced by morphine, pethidine, methadone and ketobemidone in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Brain; Citalopram; Drug Synergism; Male; Meperidine; Methadone; Morphine; Propylamines; Rats; Rats, Inbred Strains; Reaction Time; Serotonin; Serotonin Antagonists; Synaptosomes | 1985 |
Maternal-fetal transfer of abused substances: pharmacokinetic and pharmacodynamic data.
Topics: Amphetamine; Animals; Cocaine; Dronabinol; Female; Fetus; Humans; Kinetics; Lysergic Acid Diethylamide; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Nicotine; Phencyclidine; Pregnancy; Substance-Related Disorders | 1985 |
Combined use of detomidine with opiates in the horse.
Topics: Animals; Behavior, Animal; Blood Pressure; Butorphanol; Heart Rate; Horses; Hypnotics and Sedatives; Imidazoles; Meperidine; Methadone; Morphine; Narcotics; Pulmonary Gas Exchange | 1988 |
Mechanism for the opioid-induced twitch potentiations of frog's skeletal muscle.
Topics: Animals; Calcium; Dextrorphan; Etorphine; In Vitro Techniques; Meperidine; Methadone; Morphine; Muscle Contraction; Muscles; Narcotics; Rana pipiens; Stimulation, Chemical | 1986 |
Morphine discrimination in the pigeon using a color tracking procedure.
Topics: Animals; Cocaine; Color; Columbidae; Cues; Cyclazocine; Dextroamphetamine; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Response; Male; Meperidine; Methadone; Morphine; Narcotics; Pentobarbital; Phencyclidine; Psychomotor Performance | 1986 |
Displacement of the surface membrane bound calcium of the skeletal muscle fibers of the frog: effects of lanthanum and opioids.
Topics: Animals; Binding Sites; Calcium; Cell Membrane; In Vitro Techniques; Lanthanum; Meperidine; Methadone; Morphine; Muscles; Narcotics; Rana pipiens | 1985 |
Simultaneous measurement of bupivacaine, etidocaine, lidocaine, meperidine, mepivacaine, and methadone.
Topics: Anesthetics, Local; Bupivacaine; Chromatography, Gas; Etidocaine; Humans; Lidocaine; Meperidine; Mepivacaine; Methadone | 1986 |
Cross-sensitization to the excitatory effect of morphine in post-dependent rats.
Topics: Animals; Male; Meperidine; Methadone; Morphine; Morphine Dependence; Motor Activity; Pentazocine; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits.
Topics: Animals; Biological Assay; Dextrorphan; Diazepam; Dose-Response Relationship, Drug; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Levorphanol; Male; Meperidine; Methadone; Nociceptors; Pentazocine; Pentobarbital; Proadifen; Rabbits; Time Factors | 1985 |
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine | 1972 |
The search for a better analgesic.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Heroin; Humans; Hydromorphone; Levorphanol; Meperidine; Methadone; Morphinans; Morphine Dependence; Structure-Activity Relationship | 1973 |
Rapid methods of screening micro-quantities of abused drugs from urine samples for microcrystal tests.
Topics: Acids; Alkalies; Alkaloids; Chromatography, Thin Layer; Codeine; Crystallization; Crystallography; Heroin Dependence; Humans; Hydromorphone; Indicators and Reagents; Meperidine; Methadone; Methods; Morphine; Nicotine; Quinine; Substance-Related Disorders | 1973 |
Contribution of 'receptor' affinity to analgesic potency.
Topics: 1-Propanol; Analgesics; Animals; Binding, Competitive; Brain; Cyclopropanes; Fentanyl; Guinea Pigs; Hydromorphone; In Vitro Techniques; Injections, Intravenous; Levorphanol; Meperidine; Methadone; Morphinans; Morphine; Pentanols; Receptors, Drug | 1974 |
[Analgesia in myocardial infarct].
Topics: Analgesics; Diazepam; Heart; Hemodynamics; Heroin; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Myocardial Infarction; Nitrogen Oxides; Pain; Pentazocine; Respiration | 1974 |
Antagonism of acute lethality of narcotic analgesics in aggregated and isolated mice by the central cholinomimetic action of pilocarpine.
Topics: Analgesics, Opioid; Animals; Atropine; Atropine Derivatives; Crowding; Depression, Chemical; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Motor Activity; Parasympathomimetics; Pentazocine; Pilocarpine; Social Isolation; Stimulation, Chemical; Time Factors | 1974 |
[Ionization constants of several narcotic analgesics and their pain relieving activity].
Topics: Analgesics, Opioid; Benzilates; Chemical Phenomena; Chemistry, Physical; Codeine; Dextromoramide; Dimethylamines; Kinetics; Levorphanol; Meperidine; Methadone; Morphine; Muscle Relaxants, Central; Phenylacetates; Structure-Activity Relationship | 1973 |
Urine screening techniques employed in the detection of users of narcotics and their correlation with the nalorphine test.
Topics: Amphetamine; California; Cocaine; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Nalorphine; Pupil; Substance-Related Disorders | 1966 |
[Modifications of the contractility of the sphincter of Oddi under the influence of central analgesics].
Topics: Ampulla of Vater; Amyl Nitrite; Atropine; Chlorpromazine; Cholecystectomy; Humans; Hydromorphone; Meperidine; Methadone; Procaine | 1967 |
A method of identifying narcotic analgesics in human urine after therapeutic doses.
Topics: Alkaloids; Analgesics; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Humans; Hydromorphone; Ion Exchange; Levorphanol; Meperidine; Methadone; Methods; Morphine; Narcotics; Pentazocine | 1970 |
Effects of opioid narcotic drugs on energy reserves of skeletal muscle. I. Glycogen.
Topics: Animals; Calcium; Carbon Radioisotopes; Diaphragm; Drug Tolerance; Energy Metabolism; Epinephrine; Glucose; Glycogen; Glycogen Synthase; In Vitro Techniques; Male; Meperidine; Methadone; Morphinans; Morphine; Muscles; Narcotics; Phosphoglucomutase; Phosphorylases; Propranolol; Rats; Time Factors | 1974 |
[On the differential toxicity of drugs following subcutaneous, intragastric and intraduodenal application in rats].
Topics: Animals; Atropine; Duodenum; Epinephrine; Meperidine; Methadone; Parasympatholytics; Pentobarbital; Quaternary Ammonium Compounds; Rats; Scopolamine; Stomach; Xanthenes | 1968 |
Interactions of some analgesics and antidepressants with phenelzine or reserpine in the mouse.
Topics: Alphaprodine; Analgesics; Animals; Antidepressive Agents; Body Temperature; Drug Interactions; Fenclonine; Hypothermia; Imipramine; Isonipecotic Acids; Lethal Dose 50; Male; Meperidine; Methadone; Mice; Pentazocine; Phenelzine; Reserpine; Time Factors | 1974 |
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus | 1974 |
Hyposensitivity to drugs induced by morphine and some related substances in the cat.
Topics: Angiotensin II; Animals; Blood Pressure; Cats; Epinephrine; Female; Meperidine; Methadone; Morphine; Muscle, Smooth; Nalorphine; Nictitating Membrane; Norepinephrine; Tachyphylaxis; Uterus; Venous Pressure | 1970 |
Analgesically active basic anilides: stereospecificity and structure of the basic group.
Topics: Analgesics; Anilides; Animals; Behavior, Animal; Chemistry, Organic; Meperidine; Methadone; Mice; Organic Chemistry Phenomena; Sensory Receptor Cells | 1967 |
[On the inhibitory effect of kinins on isolated intestinal sections].
Topics: Anesthetics, Local; Animals; Atropine; Bradykinin; Caffeine; Duodenum; Ganglionic Blockers; Guanethidine; Ileum; Jejunum; Kallidin; Meperidine; Methadone; Morphine; Phenylbutazone; Rabbits | 1966 |
Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes.
Topics: Adult; Amines; Amphetamine; Appetite Depressants; Benzphetamine; Biological Transport; Chlorpheniramine; Chlorphentermine; Ephedrine; Fenfluramine; Furans; Humans; Hydrogen-Ion Concentration; Lidocaine; Male; Membranes; Meperidine; Mephentermine; Methadone; Models, Biological; Morpholines; Mouth; Nicotine; Phenethylamines; Phenmetrazine; Phenylpropanolamine | 1967 |
[Further studies on the effect of various drugs on the respiration].
Topics: Antifibrinolytic Agents; Benzoates; Central Nervous System Stimulants; Chlorpromazine; Humans; Meperidine; Methadone; Phenobarbital; Pulmonary Heart Disease; Respiration; Theobromine | 1968 |
Central and peripheral monoaminergic membrane-pump blockade by some addictive analgesics and antihistamines.
Topics: 5-Hydroxytryptophan; Amines; Analgesics; Animals; Biological Transport, Active; Chlorpheniramine; Diphenhydramine; Histamine H1 Antagonists; Meperidine; Methadone; Mice; Neurons; Nialamide; Norepinephrine; Serotonin; Tripelennamine | 1969 |
Screening method for detection of drugs of abuse in human urine.
Topics: Alkaloids; Amphetamine; Analgesics; Barbiturates; Chlorpheniramine; Chromatography; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonists; Hot Temperature; Humans; Indicators and Reagents; Isonipecotic Acids; Meperidine; Methadone; Methods; Morphinans; Morphine; Pentazocine; Phenacetin; Phenothiazines; Quinidine; Substance-Related Disorders; Ultraviolet Rays | 1971 |
Liquid-solid extraction of lyophilized biological material for forensic analysis. I. Application to urine samples for detection of drugs of abuse.
Topics: Acetates; Antidepressive Agents; Barbiturates; Chromatography, Thin Layer; Forensic Medicine; Freeze Drying; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Meperidine; Methadone; Methods; Morphine; Substance-Related Disorders | 1971 |
Effects of narcotic analgesics on contractions of the chick isolated, innervated oesophagus.
Topics: Acetylcholine; Analgesics; Animals; Chickens; Cyclazocine; Dextropropoxyphene; Electric Stimulation; Esophagus; Heroin; In Vitro Techniques; Meperidine; Methadone; Morphinans; Morphine; Muscle Contraction; Nalorphine; Pentazocine; Phenazocine; Serotonin; Tachyphylaxis; Time Factors | 1972 |
Optimization of extraction and separation of narcotics from urine.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors | 1974 |
Effect of acutely administered analgesic drugs on rat brain serotonin turnover.
Topics: Analgesics; Animals; Brain; Brain Chemistry; Clomipramine; Dopamine; Hydroxyindoleacetic Acid; Kinetics; Male; Meperidine; Methadone; Morphine; Naloxone; Nialamide; Norepinephrine; Pargyline; Pentazocine; Rats; Serotonin; Stimulation, Chemical; Tranylcypromine; Tryptophan | 1974 |
Interactions of narcotics and their antagonists with human serum esterase. V: Hidden agonistic effects.
Topics: Dextropropoxyphene; Dose-Response Relationship, Drug; Esterases; Humans; Hydrolysis; In Vitro Techniques; Kinetics; Meperidine; Methadone; Morphinans; Nalorphine; Narcotic Antagonists; Narcotics; Piperidines; Procaine; Protein Binding; Stimulation, Chemical | 1974 |
Induction of physical dependence on morphine, codeine and meperidine in the rat by continuous infusion.
Topics: Animals; Behavior, Animal; Body Weight; Codeine; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Injections, Intraperitoneal; Male; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorphine; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Vocalization, Animal | 1974 |
Studies on physical dependence inducible by hours exposure of mice to morphine.
Topics: Analgesia; Animals; Behavior, Animal; Body Weight; Drug Tolerance; Humans; Infusions, Parenteral; Injections; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Pentazocine; Substance Withdrawal Syndrome; Time Factors | 1972 |
A scoring system for abstinence syndrome in morphine dependent mice and application to evaluate morphine type dependence liability of drugs.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Humans; Male; Meperidine; Methadone; Mice; Morphine Dependence; Phenobarbital; Substance Withdrawal Syndrome; Time Factors | 1973 |
Effects of acutely administered analgesic drugs on rat brain 5-hydroxytryptamine turnover.
Topics: Analgesics; Animals; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Morphine; Pargyline; Pentazocine; Probenecid; Rats; Serotonin | 1972 |
[Clinical pharmacology of narcotics. II].
Topics: Chemical Phenomena; Chemistry; Hallucinogens; Humans; Lysergic Acid Diethylamide; Meperidine; Methadone; Morphinans; Morphine Dependence; Pentazocine; Substance-Related Disorders | 1972 |
Acute effects of narcotic analgesics on behavioral arousal in the rat.
Topics: Analgesics; Animals; Arousal; Dose-Response Relationship, Drug; Levorphanol; Locomotion; Male; Meperidine; Methadone; Methyltyrosines; Morphine; Narcotics; Pentazocine; Rats; Time Factors | 1973 |
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue.
Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium | 1973 |
Agonistic properties of narcotic analgesics and antagonists on the electroencephalogram and behavior in the rat and their reversal by naloxone.
Topics: Analgesics; Animals; Behavior, Animal; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Female; Meperidine; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Sleep; Time Factors | 1973 |
Some behavioral and EEG effects of a new analgesic agent (viminol) in comparison with morphine in rats.
Topics: Analgesics; Animals; Behavior, Animal; Benzyl Compounds; Butylamines; Conditioning, Operant; Dose-Response Relationship, Drug; Electroencephalography; Ethanolamines; Humans; Lethal Dose 50; Locomotion; Male; Meperidine; Meprobamate; Methadone; Morphine; Pyrroles; Rats; Substance-Related Disorders; Time Factors | 1973 |
Effect of stimulus intensity on the potency of some analgetic agents.
Topics: Analgesics; Animals; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Levorphanol; Male; Meperidine; Methadone; Mice; Mice, Inbred Strains; Naloxone; Pentazocine; Physical Stimulation; Reaction Time; Seizures; Time Factors; Tremor | 1973 |
[Social conditions and use of drugs in a group of young addicts in Oslo].
Topics: Administration, Oral; Adolescent; Adult; Alcoholism; Amphetamine; Cannabis; Educational Status; Family; Female; Humans; Injections, Intravenous; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Morphine; Narcotics; Norway; Opium; Phenmetrazine; Social Problems; Socioeconomic Factors; Substance-Related Disorders; Time Factors; Unemployment | 1973 |
Effect of midbrain raphe lesion on the antinociceptive action of morphine and other analgesics in rats.
Topics: Animals; Codeine; Dextropropoxyphene; Meperidine; Mesencephalon; Methadone; Morphine; Rats; Serotonin | 1973 |
[Ionization constants of several narcotic analgesics and their pain relieving action].
Topics: Analgesics; Codeine; Dextromoramide; Dimethylamines; Diphenylacetic Acids; Ethers, Cyclic; Hydrogen-Ion Concentration; Ions; Kinetics; Levorphanol; Mathematics; Meperidine; Methadone; Morphinans; Morphine; Narcotics; Piperidines | 1973 |
Effects of narcotic analgesics and their antagonists on the rabbit isolated heart and its adrenergic nerves.
Topics: Animals; Autonomic Nervous System; Drug Interactions; Electric Stimulation; Female; Fentanyl; Heart; Heart Rate; In Vitro Techniques; Levallorphan; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Perfusion; Rabbits; Secretory Rate; Sympathetic Nervous System | 1973 |
Anti-nociceptive activity of some thiophthalanes with morphine-like properties.
Topics: Analgesia; Analgesics; Animals; Bridged-Ring Compounds; Depression, Chemical; Dextropropoxyphene; Dimethylamines; Electric Stimulation; Ketones; Male; Meperidine; Methadone; Mice; Morphine; Pain; Piperidines; Thiophenes | 1973 |
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders | 1974 |
Routine use of a flexible gas chromatograph-mass spectrometer-computer system to identify drugs and their metabolites in body fluids of overdose victims.
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Computers; Evaluation Studies as Topic; Humans; Infant; Infant, Newborn; Male; Mass Spectrometry; Meperidine; Methadone; Methaqualone; Methods; Substance-Related Disorders | 1974 |
Thiazine dye antagonism of opioid lethality in mice.
Topics: Animals; Codeine; Dextropropoxyphene; Drug Synergism; Hexobarbital; Lethal Dose 50; Levorphanol; Male; Meperidine; Methadone; Methylene Blue; Mice; Morphinans; Morphine; Sleep; Thiazines; Time Factors; Tolonium Chloride | 1974 |
Chemical evaluation of 'drug cocktails' in autopsy specimens.
Topics: Adult; Amphetamine; Autopsy; Barbiturates; Body Fluids; Forensic Medicine; Hallucinogens; Humans; Hypnotics and Sedatives; Levallorphan; Male; Meperidine; Methadone; Methaqualone; Morphinans; Morphine; Pharmaceutical Preparations; Poisoning; Substance-Related Disorders; Tissue Extracts | 1974 |
New molecular complexes of methadone, its congeners and some other opiates with copper and iron.
Topics: Chemical Phenomena; Chemistry; Chlorides; Codeine; Copper; Crystallization; Dextropropoxyphene; Drug Stability; Heroin Dependence; Humans; Iron; Meperidine; Methadone; Solutions; Stereoisomerism | 1974 |
Methadone maintenance therapy for heroin addiction. Some surgical considerations.
Topics: Adult; Cardiac Surgical Procedures; Curettage; Dextropropoxyphene; Dilatation; Female; Fracture Fixation; Heroin; Humans; Hysterectomy; Male; Meperidine; Methadone; Orthopedics; Pain; Pentazocine; Substance Withdrawal Syndrome; Substance-Related Disorders; Surgery, Oral; Surgical Procedures, Operative | 1972 |
Mini thin-layer chromatography in the detection of narcotics in urine from subjects on a methadone maintenance program.
Topics: Chromatography, Thin Layer; Codeine; Colorimetry; Humans; Meperidine; Methadone; Methods; Morphine; Narcotics; Substance-Related Disorders | 1972 |
Treatment of morphine-type dependence by withdrawal methods.
Topics: Barbiturates; Female; Heroin; Hospitalization; Humans; Male; Meperidine; Methadone; Morphine; Pregnancy; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Tranquilizing Agents | 1972 |
Action of picric acid on the effects of some drugs acting on the central nervous system, with special reference to opioids.
Topics: Amphetamine; Analgesia; Analgesics; Animals; Benzimidazoles; Drug Synergism; Female; Male; Meperidine; Methadone; Mice; Microsomes, Liver; Morphine; Pentazocine; Pentylenetetrazole; Picrates; Seizures; Sleep; Sodium Salicylate | 1971 |
Some clinical impressions of droperidol used as premedication in children.
Topics: Adult; Atropine; Benperidol; Child; Child, Preschool; Drug Combinations; Drug Synergism; Humans; Infant; Meperidine; Methadone; Postoperative Care; Premedication; Preoperative Care; Promethazine; Scopolamine; Trimeprazine | 1971 |
Effects of narcotic analgesics and antagonists on the in vivo release of acetylcholine from the cerebral cortex of the cat.
Topics: Acetylcholine; Analgesia; Analgesics; Animals; Bridged-Ring Compounds; Cats; Cerebral Cortex; Chlorpromazine; Codeine; Dextropropoxyphene; Female; Furans; Ketones; Levallorphan; Male; Meperidine; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenanthrenes | 1971 |
An ultra rapid method for the extraction of drugs from biological fluids.
Topics: Amphetamine; Centrifugation; Chromatography, Gas; Chromatography, Thin Layer; Humans; Lipids; Meperidine; Methadone; Methamphetamine; Methods; Solubility; Solvents; Substance-Related Disorders; Time Factors | 1971 |
[Studies of the toxicity of drugs in subcutaneous, intragastric and intraduodenal administration in rats].
Topics: Animals; Atropine; Epinephrine; Gallamine Triethiodide; Isoproterenol; Meperidine; Methadone; Norepinephrine; Papaverine; Parasympatholytics; Propantheline; Quaternary Ammonium Compounds; Rats; Scopolamine; Sympathomimetics; Synephrine; Xanthenes | 1969 |
[Cause and treatment of spasticity following halothane anesthesia].
Topics: Adult; Analgesics; Anesthesia, Inhalation; Benperidol; Body Temperature; Diazepam; Halothane; Humans; Meperidine; Methadone; Postoperative Complications; Promazine; Promethazine; Shivering; Spasm | 1969 |
A quantitative method for the assessment of physical dependence on narcotic analgesics in mice.
Topics: Animals; Humans; Meperidine; Methadone; Methods; Mice; Morphine Dependence; Motor Activity; Nalorphine; Substance Withdrawal Syndrome; Substance-Related Disorders | 1969 |
Studies of drugs given before anaesthesia. XIX. The opiates.
Topics: Analgesics; Diazepam; Female; Fentanyl; Heroin; Humans; Levorphanol; Male; Meperidine; Methadone; Morphine; Papaverine; Phenazocine; Preanesthetic Medication; Vomiting | 1970 |
Action of codeine, pethidine and methadone on the operant behavior of the rat.
Topics: Animals; Avoidance Learning; Codeine; Conditioning, Operant; Depression, Chemical; Male; Meperidine; Methadone; Rats; Reinforcement, Psychology | 1970 |
Oxygen, carbon dioxide, and pH responses in arterial blood of dogs given analgesic, neuroleptanalgesic, and ataractic agents.
Topics: Analgesics; Animals; Arteries; Atropine; Carbon Dioxide; Dogs; Hydrogen-Ion Concentration; Meperidine; Methadone; Morphine; Narcotics; Neuroleptanalgesia; Oxygen; Pentazocine; Respiration; Respiratory Function Tests; Tranquilizing Agents | 1970 |
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhydramine; Histamine; Humans; Meperidine; Meprobamate; Methadone; Methods; Morphine Dependence; Pentazocine; Pyrrolidines; Rats; Salicylates; Serotonin; Substance Withdrawal Syndrome | 1970 |
The "staircase maze" and the "simple staircase" in the analysis of the psychopharmacological action of CNS depressants.
Topics: Analgesics; Animals; Barbiturates; Behavior, Animal; Central Nervous System; Chlorpromazine; Hydroxyzine; Hypnotics and Sedatives; Meperidine; Methadone; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Rats; Reserpine; Tranquilizing Agents | 1970 |
Secondary drug use among heroin users.
Topics: Adolescent; Adult; Aged; Amphetamine; Barbiturates; Cannabis; Cocaine; Crime; Educational Status; Ethnicity; Heroin; Humans; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Middle Aged; Morphine Dependence; New York; Opium; Substance-Related Disorders | 1970 |
[Acute tolerance to continuous subcutaneous infusion of morphine].
Topics: Analgesia; Animals; Drug Tolerance; Heart Rate; Injections, Subcutaneous; Male; Meperidine; Methadone; Mice; Morphine | 1970 |
Pharmacology of narcotics and antagonists as related to drug abuse.
Topics: Codeine; Heroin; Humans; Levallorphan; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorphine; Narcotic Antagonists; Stereoisomerism; Substance-Related Disorders | 1971 |
[The effects of spasmolytics on the mechanical and electrical activity of isolated rat uterus].
Topics: Acetylcholine; Action Potentials; Animals; Depression, Chemical; Female; In Vitro Techniques; Meperidine; Methadone; Morphine; Muscle Contraction; Muscles; Papaverine; Rats; Scopolamine; Stimulation, Chemical; Uterus | 1967 |
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine | 1969 |
The specific assay of basic drugs in urine by CM-cellulose chromatography using continuous drug-dye complex extraction as a detection system.
Topics: Amphetamine; Buffers; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Coloring Agents; Cyclizine; Ephedrine; Guanethidine; Guanidines; Hydrogen-Ion Concentration; Meperidine; Methadone; Morphine; Spectrophotometry; Strychnine | 1969 |
The responses of the terminal bile duct to morphine and morphine-like drugs.
Topics: Ampulla of Vater; Animals; Bile Ducts; Cats; Cattle; Dextromoramide; Dogs; In Vitro Techniques; Levorphanol; Meperidine; Methadone; Morphine; Tachyphylaxis | 1965 |
The analgesic effect of opiate-opiate antagonist combinations in the rat.
Topics: Analgesics; Animals; Levallorphan; Meperidine; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Phenazocine; Rats; Sensory Receptor Cells | 1965 |
Release of intestinal 5-hydroxytryptamine by morphine and related agents.
Topics: Acetylcholine; Animals; Apomorphine; Calcium; Cocaine; Dogs; Female; Guinea Pigs; Ileum; Injections, Intravenous; Intestinal Mucosa; Intestines; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Nicotine; Rats; Reserpine; Serotonin; Tachyphylaxis; Uterus | 1967 |
Oxygen consumption in the new-born rat and the effects of maternally administered analgesics.
Topics: Analgesics; Animals; Animals, Newborn; Female; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Oxygen Consumption; Pregnancy; Rats | 1967 |
Antagonistic action of tolazoline upon the analgesic effect of some morphine analogues.
Topics: Analgesia; Animals; Drug Antagonism; Meperidine; Methadone; Morphine; Phenazocine; Rats; Tolazoline | 1967 |
[Pain-relieving agents. 2].
Topics: Analgesics; Analgesics, Opioid; Drug Tolerance; Humans; Meperidine; Methadone; Morphine; Morphine Derivatives; Substance-Related Disorders | 1980 |
Comparative cardiac contractile actions of six narcotic analgesics: morphine, meperidine, pentazocine, fentanyl, methadone and l-alpha-acetylmethadol (LAAM).
Topics: Analgesics, Opioid; Animals; Cats; Depression, Chemical; Drug Interactions; Fentanyl; Meperidine; Methadone; Methadyl Acetate; Morphine; Myocardial Contraction; Naloxone; Pentazocine; Stimulation, Chemical | 1980 |
Opiates and thermoregulation in mice. I. Agonists.
Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone | 1980 |
Continuous naloxone infusion for opiate poisoning in infancy.
Topics: Humans; Infant; Infant, Newborn; Infusions, Parenteral; Male; Meperidine; Methadone; Naloxone; Poisoning | 1984 |
Annual report: biological evaluation of compounds for their dependence liability. IV. Drug testing program of the Committee on Problems of Drug, Dependence, Inc. (1980).
Topics: Analgesics; Animals; Benzomorphans; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Drug Evaluation; Guinea Pigs; Humans; Meperidine; Methadone; Morphinans; Morphine; National Institutes of Health (U.S.); Rats; Research Support as Topic; Spectrophotometry, Infrared; Substance-Related Disorders; United States | 1981 |
Attenuation of the behavioral effects of meperidine and normeperidine by daily administration of diazepam.
Topics: Animals; Columbidae; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Male; Meperidine; Methadone; Morphine; Pentobarbital | 1983 |
Effect of spasmolytic analgesic drugs on the motility patterns of the equine small intestine.
Topics: Acepromazine; Analgesics; Animals; Butylscopolammonium Bromide; Colic; Dipyrone; Dogs; Drug Combinations; Electrophysiology; Gastrointestinal Motility; Horses; Intestinal Diseases; Intestine, Small; Male; Meperidine; Methadone; Parasympatholytics | 1983 |
Effect of morphine and morphine-like drugs on carbachol-induced fighting in cats.
Topics: Aggression; Agonistic Behavior; Animals; Carbachol; Cats; Female; Humans; Injections, Intraventricular; Male; Meperidine; Methadone; Morphine | 1982 |
The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Epidural Space; Female; Fentanyl; Lipids; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Nociceptors; Pain; Reflex; Skin; Time Factors | 1982 |
Motility response of rats to chronic constant-dose treatment with narcotics.
Topics: Animals; Male; Meperidine; Methadone; Morphine; Motor Activity; Narcotics; Pentazocine; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Inhibition by morphine and morphine-like drugs of nicotine-induced emesis in cats.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Emetics; Female; Injections, Intraventricular; Male; Meperidine; Methadone; Morphine; Nicotine; Vomiting | 1981 |
Ketobemidone, methadone and pethidine are non-competitive N-methyl-D-aspartate (NMDA) antagonists in the rat cortex and spinal cord.
Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Meperidine; Methadone; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1995 |
Disappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists.
Topics: Adult; Aged; Analgesics, Opioid; Child; Delayed-Action Preparations; Female; Humans; Hyperalgesia; Male; Meperidine; Methadone; Middle Aged; Morphine; Myoclonus; Narcotics; Neoplasms; Pain; Sufentanil | 1994 |
Interaction between ethanol and opioids in a protozoan assay.
Topics: Animals; Dextropropoxyphene; Drug Interactions; Ethanol; Meperidine; Methadone; Movement; Narcotics; Tetrahymena pyriformis | 1994 |
Deaths among drug addicts in Denmark in 1987-1991.
Topics: Adolescent; Adult; Alcoholism; Amphetamine; Analgesics, Opioid; Barbiturates; Cannabis; Cause of Death; Denmark; Dextropropoxyphene; Female; Heroin; Humans; Male; Meperidine; Methadone; Morphine; Substance-Related Disorders; Suicide; Survival Rate | 1994 |
Drug-related deaths during the 1980s. A comparative study of drug addict deaths examined at the institutes of forensic medicine in Aarhus, Denmark and Oslo, Norway.
Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Cause of Death; Cross-Cultural Comparison; Cross-Sectional Studies; Denmark; Dextropropoxyphene; Drug Overdose; Female; Heroin Dependence; Humans; Illicit Drugs; Incidence; Male; Meperidine; Methadone; Morphine Dependence; Norway; Psychotropic Drugs; Substance-Related Disorders; Suicide; Urban Population | 1993 |
Legal opioid consumption in Denmark 1981-1993.
Topics: Analgesia; Analgesics, Opioid; Buprenorphine; Denmark; Humans; Legislation, Drug; Meperidine; Methadone; Morphine | 1995 |
International opioid consumption.
Topics: Analgesics, Opioid; Denmark; Drug Utilization; Humans; Meperidine; Methadone; Morphine; Pain | 1997 |
[Changes in the pattern of opioid analgesic consumption in Spain].
Topics: Administration, Oral; Administration, Rectal; Analgesics, Opioid; Buprenorphine; Codeine; Databases as Topic; Dextropropoxyphene; Drug Prescriptions; Humans; Injections, Intravenous; Linear Models; Meperidine; Methadone; Morphine; Pentazocine; Spain; Tilidine; Tramadol | 1997 |
Drugs for pain.
Topics: Acetaminophen; Administration, Oral; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Aspirin; Constipation; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Tolerance; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Ketorolac; Levorphanol; Meperidine; Methadone; Morphine; Narcotic Antagonists; Narcotics; Pain; Tolmetin; Tramadol | 1998 |
Opioid consumption in Spain--the significance of a regulatory measure.
Topics: Analgesics, Opioid; Drug and Narcotic Control; Drug Utilization; Fentanyl; Humans; Meperidine; Methadone; Morphine; Regression Analysis; Spain; Tilidine | 1999 |
Solid-phase microextraction for the determination of pethidine and methadone in human urine using gas chromatography with nitrogen-phosphorus detection.
Topics: Chromatography, Gas; Humans; Meperidine; Methadone; Narcotics | 1999 |
Trends in licit opioid use in Australia, 1984-1998: comparative analysis of international and jurisdictional data.
Topics: Australia; Developed Countries; Drug Utilization; Humans; Meperidine; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Practice Patterns, Physicians' | 2000 |
Liquid-phase microextraction of protein-bound drugs under non-equilibrium conditions.
Topics: Amphetamine; Haloperidol; Humans; Meperidine; Methadone; Microchemistry; Pharmaceutical Preparations; Promethazine; Proteins | 2002 |
[The new central analgesics].
Topics: Analgesics; Humans; Meperidine; Methadone; Morphinans | 1952 |
Action of analgesic drugs morphine, meperidine, methadone on rotatory nystagmus in the rabbit.
Topics: Analgesics; Animals; Meperidine; Methadone; Morphine; Nystagmus, Pathologic; Rabbits | 1953 |
The chemistry of drugs of addiction.
Topics: Barbiturates; Cannabis; Humans; Hydromorphone; Meperidine; Methadone; Morphine Derivatives | 1953 |
Clinical characteristics of addictions.
Topics: Barbiturates; Cannabis; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Substance-Related Disorders | 1953 |
[Contribution to the demonstration of dolantin, polamidon and pervitin].
Topics: Ephedrine; Meperidine; Methadone | 1952 |
[Microscopical detection of morphine-like compounds].
Topics: Analgesics; Meperidine; Methadone; Morphine | 1953 |
Analgesics and enzymes of the cytochrome chain.
Topics: Analgesics; Brain; Cytochromes; Meperidine; Methadone; Morphine; Myocardium; Oxidoreductases | 1953 |
[Methadon and pathidine derivatives, hazards in public sale, heptane].
Topics: Analgesics; Behavior, Addictive; Commerce; Heptanes; Humans; Meperidine; Methadone; Substance-Related Disorders | 1953 |
[Effect of drugs on the metabolism of pyruvate in fetuses and young animals. II. Morphine and synthetic morphine simulants].
Topics: Animals; Central Nervous System; Fetus; Liver; Meperidine; Methadone; Morphine; Pyruvates; Pyruvic Acid | 1953 |
The depression of respiration by the opiates and its antagonism by nalorphine.
Topics: Analgesics, Opioid; Depression; Depressive Disorder; Humans; Meperidine; Methadone; Morphine; Nalorphine; Respiration | 1953 |
Synthetic substances with morphine-like effect; chemical aspects.
Topics: Meperidine; Methadone; Morphine Derivatives | 1954 |
[The effect of morphine, pethidine and methadon on peristaltic activity of intestines].
Topics: Intestines; Meperidine; Methadone; Morphine; Peristalsis | 1954 |
[Some phenomena of synergism. I. Associations of analgesics and of a spasmolytic considered as their structural analog].
Topics: Analgesics; Cardiovascular Agents; Inorganic Chemicals; Meperidine; Methadone; Muscle Relaxants, Central; Parasympatholytics | 1955 |
Effect of adrenaline on the analgesic response of mice to morphine and related drugs.
Topics: Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Animals; Epinephrine; Meperidine; Methadone; Mice; Morphine; Pain Management | 1955 |
Drug addiction and other considerations in the management of pain with narcotic drugs.
Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narcotics; Pain; Substance-Related Disorders | 1957 |
The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum.
Topics: Acetylcholine; Codeine; Drug Tolerance; Guinea Pigs; Heroin; Ileum; Intestines; Meperidine; Methadone; Morphine; Nalorphine | 1957 |
[Action of various synthetic analgesics in comparison with morphine & its derivatives].
Topics: Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Ephedrine; Meperidine; Methadone; Morphine; Pain Management | 1957 |
A new series of potent analgesics: dextro 2:2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine and related basic amides. II. Comparative analgesic activity, acute toxicity and tolerance development in rats for R875, morphine, pethidine and methadone.
Topics: Amides; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Biphenyl Compounds; Drug Tolerance; Meperidine; Methadone; Morphine; Rats | 1958 |
A study of the selective antagonism by N-allylnormorphine against meperidine, methadone, and morphine.
Topics: Meperidine; Methadone; Morphine; Nalorphine | 1958 |
[Proposal to the supplement of the 6th edition of the German Pharmacopeia. 6. Pethidin hydrochloride & methadon hydrochloride].
Topics: Dietary Supplements; Ethnicity; Humans; Meperidine; Methadone | 1958 |
[Proposals for the supplement to the 6th edition of the German pharmacopeia. 6. Pethidine hydrochloride & methandon hydrochloride].
Topics: Dietary Supplements; Ethnicity; Humans; Meperidine; Methadone | 1958 |
Comparative effects of analgesics on pain threshold, respiratory frequency and gastrointestinal propulsion.
Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antipyretics; Cell Respiration; Codeine; Dextromoramide; Gastrointestinal Tract; Guinea Pigs; Meperidine; Methadone; Morphine; Nalorphine; Pain; Pain Threshold; Rats; Respiration; Respiratory Rate | 1959 |
Multiple toe-pinch method for testing analgesic drugs.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Chlorpromazine; Codeine; Guinea Pigs; Humans; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Morphine; Nalorphine; Phencyclidine; Phthalic Acids; Rats; Toes | 1961 |
[The effect of various pharmacological agents (amphetamine, cocaine, caffeine, hexobarbital, meprobamate, morphine, dextromoramide, 1-methadone, pethidine and CT 3570) on the time of exhaustion and behavior of animals swimming at 20 degrees C].
Topics: Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior; Caffeine; Central Nervous System Stimulants; Cocaine; Dextromoramide; Hexobarbital; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed | 1960 |
The control of injections and other pharmaceutical preparations by means of U.V. spectrophotometry as a standard analytical tool. VI. Spectrophotometric assay of atropine sulfate, pethidine hydrochloride and methadone hydrochloride (Symoron).
Topics: Atropine; Biological Assay; Injections; Meperidine; Methadone; Spectrophotometry | 1961 |
[Determination of methadone and pethidine in some galenical preparations. 2. Suppositories and injectables].
Topics: Injections; Meperidine; Methadone; Pessaries; Suppositories | 1961 |
Cross-cellular adaptation to methadone and meperidine in cerebral cortical slices from morphinized rats.
Topics: Animals; Cerebral Cortex; Meperidine; Methadone; Morphine; Rats | 1962 |
Analgesia in electromyography.
Topics: Analgesia; Electromyography; Humans; Meperidine; Methadone; Pain; Pain Management; Promethazine | 1963 |
[Behavior modifiers inthe study of bile ducts. (Combined action of morphine substances and cholecystokinin)].
Topics: Ampulla of Vater; Bile Ducts; Cholecystokinin; Codeine; Dextromoramide; Hydromorphone; Meperidine; Methadone; Morphine; Opium | 1963 |
A DIRECT TITRIMETRIC METHOD FOR THE DETERMINATION OF SOME ORGANIC BASES IN PHARMACEUTICAL PREPARATIONS.
Topics: Atropine; Chemistry, Pharmaceutical; Codeine; Meperidine; Methadone; Pharmacy; Research | 1963 |
[THE INHIBITION OF MORPHINE, LEVORPHAN, METHADONE AND PETHIDINE ANALGESIA IN MICE BY "SPECIFIC" AND "NONSPECIFIC" ANTAGONISTS].
Topics: Analgesia; Animals; Atropine; Levorphanol; Meperidine; Mephenesin; Meprobamate; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain Management; Peptides; Phenobarbital; Research; Reserpine; Tissue Extracts | 1963 |
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS.
Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology | 1964 |
ELEVATION OF PLASMA HISTAMINE LEVELS IN THE DOG FOLLOWING ADMINISTRATION OF MUSCLE RELAXANTS, OPIATES AND MACROMOLECULAR POLYMERS.
Topics: Acacia; Analgesics, Opioid; Blood Chemical Analysis; Codeine; Dextrans; Diatrizoate; Dogs; Histamine; Meperidine; Mesylates; Methadone; Morphine; Muscle Relaxants, Central; Niacin; Nicotinic Acids; Pharmacology; Povidone; Research; Starch; Succinylcholine; Tubocurarine | 1964 |
DOUBLE BLIND TRIAL OF DEXTROMORAMIDE, METHADONE AND PETHIDINE IN THE TREATMENT OF SEVERE PAIN.
Topics: Dextromoramide; Double-Blind Method; Humans; Meperidine; Methadone; Pain; Toxicology | 1964 |
ANALGESICS FOR THE RELIEF OF PAIN. I. NARCOTIC ANALGESICS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pain; Phenazocine; Piperidines | 1964 |
[RE-ANESTHESIA].
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, General; Anesthesiology; Atropa belladonna; Atropine; Barbiturates; Chlorpromazine; Dihydroergotoxine; Ergot Alkaloids; Humans; Meperidine; Methadone; Morphine; Procainamide; Promazine; Promethazine; Reserpine; Scopolamine | 1964 |
EXPERIMENTAL NARCOTIC ADDICTION.
Topics: Animals; Codeine; Conditioning, Psychological; Equipment and Supplies; Haplorhini; Injections, Intravenous; Meperidine; Methadone; Morphine Dependence; Nalorphine; Opioid-Related Disorders; Rats; Substance-Related Disorders | 1964 |
STATISTICS AS APPLIED TO PHARMACOLOGICAL AND TOXICOLOGICAL SCREENING.
Topics: Arsphenamine; Atropine; Biological Assay; Biometry; Cocaine; Digoxin; Epinephrine; Ergonovine; Ergot Alkaloids; Hexamethonium Compounds; Histamine; Insulin; Meperidine; Methadone; Morphine; Pharmacology; Promethazine; Research; Riboflavin; Statistics as Topic; Strophanthins; Toxicology; Tubocurarine | 1963 |
BARBITURATE USE IN NARCOTIC ADDICTS.
Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine Dependence; Narcotics; Opium; Pentobarbital; Seizures; Statistics as Topic; Substance-Related Disorders; Toxicology; Urea | 1964 |
STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS. I. ABSOLUTE CONFIGURATION OF CERTAIN ANALGESIC (-)-N-(2-(PHENALKYLMETHYLAMINO)PROPYL)PROPIONANILIDES.
Topics: Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Meperidine; Methadone; Morphine; Pharmacology; Pharmacy; Research | 1964 |
QUANTITATIVE STUDIES OF THE ANTAGONISM BY NALORPHINE OF SOME OF THE ACTIONS OF MORPHINE-LIKE ANALGESIC DRUGS.
Topics: Analgesics; Animals; Body Temperature; Dextromoramide; Lens, Crystalline; Levorphanol; Meperidine; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pharmacology; Research; Skin | 1964 |
A RAPID SCREENING TEST FOR POTENTIAL ADDICTION LIABILITY OF NEW ANALGESIC AGENTS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior, Addictive; Codeine; Dextropropoxyphene; Heroin; Hydromorphone; Meperidine; Methadone; Mice; Morphine; Phenazocine; Research; Substance-Related Disorders; Toxicology | 1964 |
CONGENITAL NEONATAL NARCOTICS ADDICTION: A NATURAL HISTORY.
Topics: Chlorpromazine; Female; Humans; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine Dependence; Mortality; Narcotics; Opioid-Related Disorders; Opium; Phenobarbital; Pregnancy; Psychotherapy; Social Conditions; Substance-Related Disorders | 1964 |
THE ACTION OF MORPHINE-LIKE DRUGS ON IMPULSE TRANSMISSION IN MAMMALIAN NERVE FIBRES.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Cats; Conditioning, Psychological; Hypogastric Plexus; Lagomorpha; Mammals; Meperidine; Methadone; Morphine; Nalorphine; Nerve Fibers; Neural Conduction; Nictitating Membrane; Pharmacology; Rabbits; Research; Sympathetic Nervous System | 1964 |
[CONTROLLABLE APNEA IN ANESTHESIA BY MEANS OF CENTRAL DEPRESSION DUE TO ANALGESICS].
Topics: Analgesics; Anesthesia; Apnea; Central Nervous System Agents; Depression; Dextromoramide; Humans; Meperidine; Methadone; Morphine; Nalorphine | 1964 |
[ANALGESIA FOLLOWING GYNECOLOGICAL OPERATIONS].
Topics: Analgesia; Drug Therapy; Female; Genital Diseases, Female; Humans; Meperidine; Methadone; Pain; Phenothiazines; Surgical Procedures, Operative | 1965 |
FLUOROMETRIC IDENTIFICATION OF SUB-MICROGRAM AMOUNTS OF MORPHINE AND RELATED COMPOUNDS ON THIN-LAYER CHROMATOGRAPHS.
Topics: Chemistry, Pharmaceutical; Chromatography; Fluorescence; Fluorometry; Meperidine; Methadone; Morphine; Nalorphine; Research | 1964 |
CARDIOVASCULAR ACTIONS OF NARCOTIC ANALGESICS.
Topics: Cardiovascular Diseases; Drug Therapy; Humans; Meperidine; Methadone; Morphine; Narcotics; Pharmacology; Toxicology | 1965 |
A METHOD FOR THE THIN-LAYER CHROMATOGRAPHY OF ANALGESIC DRUGS AND RELATED COMPOUNDS IN NON-AQUEOUS SYSTEMS.
Topics: Ammonia; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Azepines; Chromatography; Chromatography, Thin Layer; Cocaine; Codeine; Dextropropoxyphene; Isonipecotic Acids; Meperidine; Methadone; Morphine; Research | 1965 |
EFFECT OF CENTRAL DEPRESSANT AGENTS ON CEREBRAL GLUCOSE 6-PHOSPHATE DEHYDROGENASE ACTIVITY OF RATS.
Topics: Adrenal Glands; Brain; Chloroform; Erythrocytes; Ethanol; Glucose; Glucosephosphate Dehydrogenase; Kidney; Liver; Meperidine; Methadone; Morphine; NADP; Nalorphine; Pentobarbital; Pharmacology; Phosphates; Rats; Research; Spleen; Sulfhydryl Compounds | 1965 |
[Analgetic effect of morphine, dolsin and mecodin in various ways of application; a pharmacological study].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Meperidine; Methadone; Morphine; Pain; Pain Management | 1955 |
[Action of various pharmacological agents on the exhaustion time and behavior of mice swimming at 20 degrees C. II. Analgesics (morphine, dextromoramide, methadone, pethidine and 3570 CT). Influence of repetition of the test].
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Dextromoramide; Fatigue; Leadership; Meperidine; Methadone; Mice; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed | 1962 |
Variable modulation of opioid brain uptake by P-glycoprotein in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzomorphans; Biological Transport; Brain; Drug Interactions; Fentanyl; Loperamide; Meperidine; Methadone; Mice; Narcotics; Quinidine; Time Factors; Verapamil | 2004 |
Therapeutics and toxicology.
Topics: Anemia; Anemia, Pernicious; Antacids; Anti-Bacterial Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure; Cortisone; Dibenzylchlorethamine; Dicumarol; Epilepsy; Ergot Alkaloids; Heart Failure; Heparin; Histamine Antagonists; Humans; Hyaluronoglucosaminidase; Hydantoins; Hypersensitivity; Hypertension; Hyperthyroidism; Imidazoles; Iodine; Iodine Isotopes; Kidney; Meperidine; Mephenesin; Methadone; Motion Sickness; Norepinephrine; Organomercury Compounds; Peptic Ulcer; Tetraethylammonium; Therapeutics; Thiouracil; Thrombosis; Veratrum; Vitamin B 12 | 1950 |
The action of morphine, pethidine, and amidone upon the intestinal motility of conscious dogs.
Topics: Animals; Consciousness; Dogs; Gastrointestinal Motility; Humans; Intestines; Meperidine; Methadone; Morphine | 1950 |
The effects of morphine methadone and meperidine on some reflex responses of spinal animals to nociceptive stimulation.
Topics: Animals; Meperidine; Methadone; Morphine; Reflex | 1951 |
Studies on a new spasmolytic compound 1,1-diphenyl-3-dimethylaminobutene-1 (A29), related to methadone, and on the combined use of this compound and a potent analgesic, ketobemidone (A21).
Topics: Analgesics; Biphenyl Compounds; Humans; Meperidine; Methadone; Parasympatholytics; Piperidines | 1951 |
[Determination of polamidon and dolantin in the urine, and their separation from morphine].
Topics: Body Fluids; Meperidine; Methadone; Morphine; Rare Diseases; Retinal Degeneration; Retinal Detachment; Urine | 1951 |
[Effect of morphine, dolantin and polamidon on the small intestine of man].
Topics: Intestine, Small; Intestines; Meperidine; Methadone; Morphine | 1951 |
"Opioid creep" is real and may be the cause of "fluid creep".
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Body Surface Area; Burns; Female; Fentanyl; Fluid Therapy; Humans; Hypnotics and Sedatives; Male; Meperidine; Methadone; Middle Aged; Morphine; Narcotics; Retrospective Studies | 2004 |
A comparison of the antidiuretic effect of demerol and of methadone diuresis in congestive heart failure; a case report.
Topics: Antidiuretic Agents; Diuresis; Diuretics; Heart; Heart Failure; Humans; Meperidine; Methadone | 1949 |
On pethidine and methadone derivatives.
Topics: Meperidine; Methadone | 1949 |
A comparison of the actions of meperidine, Nu-1196, methadone, morphine, Nu-2206, and metopon upon the intestine and uterus.
Topics: Female; Humans; Intestines; Meperidine; Methadone; Morphinans; Morphine; Uterus | 1950 |
A comparison of certain actions of demerol and methadone.
Topics: Humans; Meperidine; Methadone; Morphine; Narcotics | 1949 |
Inhibition of succinic oxidase system by meperidine, methadon, morphine, and codeine.
Topics: Codeine; Coloring Agents; Meperidine; Methadone; Morphine; Oxidoreductases; Peroxidase; Peroxidases; Succinate Dehydrogenase | 1949 |
OCCURRENCE IN RODENTS OF REVERSIBLE DRUG-INDUCED OPACITIES OF THE LENS.
Topics: Analgesics, Opioid; Animals; Cataract; Chickens; Guinea Pigs; Humans; Injections, Subcutaneous; Lens Capsule, Crystalline; Lens, Crystalline; Meperidine; Methadone; Mice; Morphine; Pupil; Rats; Recovery of Function | 1961 |
Comparative study of some actions of demerol and methadon.
Topics: Humans; Meperidine; Methadone | 1948 |
Analgesic effects in human subjects of morphine, meperidina and methadon.
Topics: Analgesics; Humans; Meperidine; Methadone; Morphine; Morphine Derivatives | 1948 |
Acute vascular tolerance to morphine, isonipecaine (demerol) and methadon (amidone) in the dog.
Topics: Animals; Blood Vessels; Dogs; Drug Tolerance; Immune Tolerance; Meperidine; Methadone; Morphine | 1948 |
Some effects of 1-methyl-4-phenyl ethyl isonipecotate (demerol) and 6-dimethylamino-4,4,-diphenyl-3-heptanone (amidone) upon the metabolism of rat brain tissue in vitro.
Topics: Animals; Biphenyl Compounds; Brain; In Vitro Techniques; Ketones; Meperidine; Methadone; Rats | 1947 |
Acute vascular tolerance to morphine, demerol, and 1,1-diphenyl-1-(dimethylamino-isopropyl) butanone-2 (amidone) in the dog.
Topics: Animals; Biphenyl Compounds; Butanones; Dogs; Drug Tolerance; Humans; Meperidine; Methadone; Morphine | 1947 |
Topical methadone and meperidine analgesic synergy in the mouse.
Topics: Administration, Cutaneous; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Lidocaine; Male; Meperidine; Methadone; Mice; Mice, Inbred Strains; Morphine; Pain Measurement | 2010 |
Determination of stimulants and narcotics as well as their in vitro metabolites by online CE-ESI-MS.
Topics: 2-Propanol; Amphetamine; Animals; Codeine; Electrophoresis, Capillary; Ephedrine; Heroin; Hydrogen-Ion Concentration; Male; Meperidine; Methadone; Microsomes, Liver; Narcotics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tetracaine | 2011 |
Is maternal opioid use hazardous to breast-fed infants?
Topics: Age Factors; Analgesics, Opioid; Breast Feeding; Buprenorphine; Codeine; Female; Humans; Hydrocodone; Infant; Infant, Newborn; Meperidine; Methadone; Milk, Human; Morphine; Oxycodone | 2012 |
Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine.
Topics: Diphenhydramine; Humans; Limit of Detection; Linear Models; Liquid Phase Microextraction; Meperidine; Methadone; Nortriptyline; Pharmaceutical Preparations; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2012 |
Nano-electromembrane extraction.
Topics: Electricity; Electrophoresis, Capillary; Ethers; Haloperidol; Loperamide; Membranes, Artificial; Meperidine; Methadone; Nanotechnology; Nortriptyline; Sodium Chloride; Solutions; Sulfates; Water | 2013 |
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry | 2014 |
LC-MS-MS Method for the Analysis of Miscellaneous Drugs in Wastewater During Football Games III.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Residues; Fentanyl; Football; Humans; Illicit Drugs; Limit of Detection; Meperidine; Methadone; Mississippi; Phencyclidine; Pyrrolidines; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater | 2016 |
Declines and regional variation in opioid distribution by U.S. hospitals.
Topics: Analgesics, Opioid; Buprenorphine; Codeine; Hospitals; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Oxymorphone; United States | 2022 |
Sedation quality of alfaxalone associated with butorphanol, methadone or pethidine in cats injected into the supraspinatus or the quadriceps muscle.
Topics: Anesthesia; Animals; Butorphanol; Cat Diseases; Cats; Hypnotics and Sedatives; Injections, Intramuscular; Meperidine; Methadone; Mydriasis; Pregnanediones; Quadriceps Muscle; Rotator Cuff | 2022 |