methadone and meperidine

methadone has been researched along with meperidine in 234 studies

Research

Studies (234)

TimeframeStudies, this research(%)All Research%
pre-1990195 (83.33)18.7374
1990's18 (7.69)18.2507
2000's10 (4.27)29.6817
2010's9 (3.85)24.3611
2020's2 (0.85)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bodinier, MC; Bonnet, B; Chapelain, B; Déprez, B; Eckhoff, C; Horvath, D; Poulain, R1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Nagashima, R; Nishikawa, T; Tobita, M1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Mehta, VL1
McIndewar, I; Sugrue, MF1
Oka, T; Sawa, A1
Blundell, C; Slater, P1
Dvorchik, BH; Hartman, RD; Stenger, VG1
Bergmann, F; Chaimovitz, M; Pasternak, V1
Hosoya, K; Oka, T1
Oka, T1
Dewey, WL; Forbes, JE1
Gianutsos, G; Lal, H; Puri, SK1
Kreek, MJ; Oratz, M; Rothschild, MA1
Lumb, WV; Pippi, NL1
Cheung, S; Sancilio, LF1
Muir, WW; Sheehan, WC; Skarda, RT1
Leander, JD; McMillan, DE1
Gibson, TC1
Deacon, MA; Iorio, LC; Ryan, EA1
Alkadhi, KA; Hogan, YH1
Jiang, Z1
Ennis, M; Lorenz, W; Nehring, E; Schneider, C1
Bundgaard, H; Christrup, L; Fullerton, A1
Kaa, E1
Dickenson, AH; McQuay, HJ; Smallman, K; Sullivan, AF1
Koren, G; Maurice, L1
Kaa, E; Steentoft, A; Worm, K1
Deshpande, JK; Maxwell, LG; Yaster, M1
Carino, MA; Horita, A; Yamawaki, S1
Hyttel, J; Larsen, JJ1
Chiang, CN; Lee, CC1
Wood, M1
Clarke, KW; Paton, BS1
Frank, GB; Shetty, SS2
Paule, MG; Wenger, GR1
Coyle, DE; Denson, DD1
Babbini, M; Bacchi, A; Bartoletti, M; Gaiardi, M; Gubellini, C1
Bowman, ER; Brase, DA; Dewey, WL; Kachur, JF; Martin, BR; Rosemond, R; Welch, S1
Gorodetzky, CW1
Eddy, NB; May, EL1
Baden, MM; Huang, JC1
Terenius, L1
Kreuzer, H; Spiller, P1
Caldwell, J; Sever, PS1
Brister, CC; Davis, WM2
Prianishnikova, NT; Raevskii, KS2
Elliott, HW; Hine, CH; Nomof, N; Parker, KD1
Juvara, I; Radulesco, D1
Fujimoto, JM; Wang, RI1
Gourley, DR1
Stockhaus, K; Wick, H2
Ahtee, L; Jounela, AJ; Saarnivaara, L; Simola, I1
Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A1
Contreras, E; Huidobro, F1
Collier, HO; Roy, AC1
Casy, AF; Hassan, MM1
Bauer, G; Konzett, H; Ziegler, E1
Beckett, AH; Triggs, EJ1
Julich, H1
Carlsson, A; Lindqvist, M1
Eddy, NB; Friebel, H; Hahn, KJ; Halbach, H1
Beattie, JM; Demetriou, JA; Lowe, ML; Weissman, N1
Andryauskas, S; Broich, JR; Goldner, SJ; Hoffman, DB; Umberger, CJ1
Bowman, WC; Buwembo, JB1
Higgins, TN; Taylor, JD1
Goodlet, I; Sugrue, MF2
Capetola, RJ; Gero, A1
Teiger, DG1
Kaneto, H; Koida, M; Nakanishi, H1
Kaneto, H; Koida, M; Nakanishi, H; Sasano, H1
Vandam, LD1
Stetson, JB1
Fernandes, M1
Carmichael, FJ; Israel, Y1
Colasanti, B; Khazan, N1
Babbini, M; Bartoletti, M; Gaiardi, M1
Granat, FR; Saelens, JK1
Andersen Lund, BM; Ellekjaer, EF1
Ghezzi, D; Mauron, C; Samanin, R; Valzelli, L1
Montel, H; Starke, K1
Fjalland, B; Lassen, N; Nielsen, IM; Pedersen, V; Petersen, PV1
Gorodetzky, CW; Kullberg, MP1
Biemann, K; Costello, CE; Hertz, HS; Sakai, T1
Burke, DH; Mann, DE1
Holder, AT; Robinson, AE1
Misra, AL1
Dundee, JW; Jones, PO1
Cushman, P1
Ho, IK; Loh, HH; Way, EL1
Huidobro, F1
Dickson, DN1
Jhamandas, K; Phillis, JW; Pinsky, C1
Campbell, DB; Ramsey, J1
Gozon, F1
Marshall, I; Weinstock, M1
Dundee, JW; Loan, WB; Morrison, JD1
Molinengo, L; Ricci-Gamalero, S2
Bendick, F; Greenwald, W; Short, CE1
Lorenzetti, OJ; Sancilio, LF1
Langrod, J1
Kamei, C; Kaneto, H; Nakanishi, H; Shimomura, K1
Elliott, HW1
Vallvé, C1
Blumberg, AG; Heaton, AM1
McMartin, C; Simpson, P; Thorpe, N1
Benzi, G; Berté, F; Crema, A; Frigo, GM1
Chernov, HI; Grumbach, L1
Burks, TF; Long, JP1
Blane, GF1
Contreras, E; Quijada, L; Tamayo, L1
Noess, K1
Amsterdam, EA; Henderson, GL; Mason, DT; Rendig, SV1
Pybus, DA; Torda, TA1
Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE1
Tenenbein, M1
Jacobson, AE1
Leander, JD1
Davies, JV; Gerring, EL1
Beleslin, DB; Krstić, SK; Stefanović-Denić, K1
Tung, AS; Yaksh, TL1
Davis, WM; Hemnani, KL; Pace, HB1
Beleslin, DB; Krstić, SK; Mićić, D; Stefanović-Denić, K; Strbac, M1
Andersen, S; Ebert, B; Krogsgaard-Larsen, P1
Jensen, NH; Jensen, TS; Sjøgren, P1
Henry, JA; Wu, C1
Kaa, E; Kringsholm, B; Simonsen, KW; Steentoft, A; Worm, K1
Kaa, E; Teige, B1
Hamunen, K1
Borgbjerg, FM; Eriksen, J; Groth Clausen, T1
Clausen, TG1
Alvarez Requejo, A; Caro-Patón, T; Carvajal, A; García del Pozo, J; Martín Arias, LH; Martín de Diego, I; Rueda, AM1
Andersen, S; Christrup, LL; Ebert, B; Hjeds, H; Thorkildsen, C1
Cano del Pozo, MI; Carvajal, A; García del Pozo, J; Martín Arias, LH; Rueda de Castro, AM1
Kim, M; Kim, S; Kim, TJ; Lee, JC; Myung, SW; Park, JH1
Berbatis, CG; Bulsara, M; Lintzeris, N; Sunderland, VB1
Ho, TS; Pedersen-Bjergaard, S; Rasmussen, KE1
WILBRANDT, W1
LONGO, VG; NAPOLITANO, L1
MAY, EL1
ISBELL, H; WHITE, WM1
VOGEL, G1
BRANDSTATTER, M1
BAIN, JA; WANG, RI1
CARRATALA, R; COSENTINO, R; COSTA, AJ1
SANTARATO, R1
BODMAN, RI1
BRAENDEN, OJ; WOLFF, PO1
MILOSEVIC, MP2
ANGIBEAUD, P; BUCHEL, L; LEVY, J1
FAUCETT, RL1
PATON, WD1
HADICKE, M; KUNTZE, M1
JAGENEAU, AH; JANSSEN, PA1
LYNCH, TA; MEYERS, DB1
HADICKE, M; POETHKE, W; WIGERT, R2
GREEN, AF1
COLLIER, HO; SKERRY, R; WARNER, BT1
JACOB, J; MICHAUD, G2
REKKER, RF; van der POL, H1
RUTSCHMANN, T1
TAKEMORI, AE2
LAJOIE, WJ1
PARIS, J; U BOIS, R; VANDENDORP, F1
JOHNSON, CA; KING, RE1
JACOBSEN, FG; SCHAFII-LASCHTENESCHAI, AH; ZETLER, G1
COLLINS, RJ; MACGREGOR, DW; WEEKS, JR1
THOMPSON, WL; WALTON, RP1
MATTS, SG1
MEYERSTEIN, AN1
WANG, RI1
KOERNER, M1
WEEKS, JR1
STEWART, GA; YOUNG, PA1
CHAPPEL, CI; VONSEEMANN, C1
HAMBURGER, E1
LASAGNA, L1
LARSON, DL; PORTOGHESE, PS1
COX, BM; WEINSTOCK, M1
SHEMANO, I; WENDEL, H1
KRUG, DC; PATRICK, SW; ROSENTHAL, T1
KOSTERLITZ, HW; WALLIS, DI1
PESCE, A; RUGIERO, G1
BOLDINO, G1
BURKHALTER, A; KUPFERBERG, HJ; WAY, EL1
ABDEL-RAHMAN, MA; ELLIOTT, HW1
CLARK, JP1
ANDERSON, RC; EMMERSON, JL1
HORAKOVA, Z; VOTAVA, Z1
Dagenais, C; Graff, CL; Pollack, GM1
SALTER, WT1
STREETEN, DH; WILLAMS, EM1
BENNETT, DR; HENDERSHOT, LC; HOUDE, RW; IRWIN, S; SEEVERS, MH1
PETERSEN, PV1
VIDIC, E1
ENGELHARDT, H; KEWITZ, H; REMMER, H1
Carrougher, GJ; Engrav, LH; Friedrich, JB; Gibran, NS; Heckbert, SR; Heimbach, DM; Honari, S; Klein, MB; Lezotte, DC; Round, KA; Sullivan, SR; Wiechman, SA1
STEELE, CW1
WOLFF, PO1
GRUBER, CM; LEE, KS1
BUCHANAN, OH; TAINTER, ML1
WATTS, DT1
Stewart, HC; Weinstock, M1
TAINTER, ML1
CHRISTENSEN, EM; GROSS, EG1
JOHNSON, HT; SHIDEMAN, FE2
ELLIOTT, HW; JAMES, HP; WARRENS, AE1
Kolesnikov, YA; Oksman, G; Pasternak, GW1
Cai, Z; Chen, G; Lai, Y; Li, Q; Lu, M; Qiu, B; Zhang, L1
Hendrickson, RG; McKeown, NJ1
Flø, L; Hansen, SH; Janfelt, C; Pedersen-Bjergaard, S; Thunig, J1
Hansen, SH; Jensen, H; Li, B; Payán, MD; Pedersen-Bjergaard, S; Petersen, NJ1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
ElSohly, MA; Godfrey, M; Gul, SW; Gul, W; Stamper, B1
Eidbo, SA; Hagedorn, JD; Kaufman, DE; Kropp Lopez, AK; Mathew, V; McCall, KL; Nichols, SD; Piper, BJ1
Bellocchi, F; Bufalari, A; Giannettoni, G; Menchetti, L; Moretti, G; Nannarone, S; Pepe, A1

Reviews

15 review(s) available for methadone and meperidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Cholinergic mechanisms in narcotic analgesics.
    Neuropharmacology, 1975, Volume: 14, Issue:12

    Topics: Acetylcholine; Analgesics, Opioid; Animals; Brain Chemistry; Cats; Chlorpromazine; Choline; Meperidine; Methadone; Morphine; Nalorphine; Neurons; Neurotransmitter Agents; Parasympathetic Nervous System; Time Factors

1975
The heart in myasthenia gravis.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans; Lidocaine; Meperidine; Methadone; Morphine; Myasthenia Gravis; Myocarditis; Myocardium; Neuromuscular Junction; Phenytoin; Procaine; Quinidine; Vectorcardiography

1975
Pediatric uses of opioids.
    Pediatric clinics of North America, 1989, Volume: 36, Issue:5

    Topics: Child; Child, Preschool; Codeine; Drug Interactions; Fentanyl; Humans; Infant; Infant, Newborn; Meperidine; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Pediatrics; Receptors, Opioid

1989
The pharmacologic management of pain in children.
    Comprehensive therapy, 1989, Volume: 15, Issue:10

    Topics: Analgesia, Epidural; Analgesics; Child; Child, Preschool; Codeine; Fentanyl; Humans; Infant; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Pain

1989
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors

1986
The biochemical pharmacology of abused drugs. III. Cannabis, opiates, and synthetic narcotics.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:6

    Topics: Animals; Cannabis; Chemical Phenomena; Chemistry; Columbidae; Cricetinae; Dronabinol; Drug Tolerance; Half-Life; Humans; Memory, Short-Term; Meperidine; Methadone; Microsomes, Liver; Morphine; Narcotics; Neurotransmitter Agents; Opium; Pentazocine; Perception; Rats; Substance-Related Disorders; Synaptic Transmission; Teratogens

1974
Hypothesis: Inhibition of E prostaglandin-sensitive adenyl cyclase as the mechanism of morphine analgesia.
    Prostaglandins, 1974, Sep-10, Volume: 7, Issue:5

    Topics: Adenylyl Cyclases; Animals; Aspirin; Brain; Cyclic AMP; Depression, Chemical; Fluorides; Guinea Pigs; Heroin; In Vitro Techniques; Levorphanol; Meperidine; Methadone; Mice; Morphinans; Morphine; Naloxone; Prostaglandin Antagonists; Prostaglandins; Rabbits; Rats; Receptors, Drug; Sodium; Stimulation, Chemical

1974
Codeine and its alternates for pain and cough relief . 4. Potential alternates for cough relief.
    Bulletin of the World Health Organization, 1969, Volume: 40, Issue:5

    Topics: Alkaloids; Animals; Antitussive Agents; Cats; Codeine; Cough; Dogs; Guinea Pigs; Histamine H1 Antagonists; Humans; Isoquinolines; Meperidine; Methadone; Mice; Morphinans; Phenanthrenes; Phenothiazines; Rats; Substance-Related Disorders

1969
Drug therapy: analgetic drugs--the potent analgetics.
    The New England journal of medicine, 1972, Feb-03, Volume: 286, Issue:5

    Topics: Analgesics; Blood Circulation; Fentanyl; Humans; Intestines; Levallorphan; Meperidine; Methadone; Methotrimeprazine; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Nausea; Pain; Pentazocine; Psychopharmacology; Respiration; Substance-Related Disorders; Urinary Tract; Vomiting

1972
Opioid analgesics as noncompetitive N-methyl-D-aspartate (NMDA) antagonists.
    Biochemical pharmacology, 1998, Sep-01, Volume: 56, Issue:5

    Topics: Analgesics, Opioid; Animals; Binding, Competitive; Dextropropoxyphene; Excitatory Amino Acid Antagonists; Humans; Meperidine; Methadone; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1998
DRUG ADDICTION: A REVIEW.
    The Journal of school health, 1964, Volume: 34

    Topics: Adolescent; Amphetamine; Amphetamines; Barbiturates; Cannabis; Codeine; Heroin; Humans; Hydromorphone; Jurisprudence; Meperidine; Mescaline; Methadone; Morphine Dependence; Nalorphine; Narcotic Antagonists; Psychotherapy; Statistics as Topic; Substance-Related Disorders

1964
ANTITUSSIVE DRUGS.
    Progress in medicinal chemistry, 1963, Volume: 19

    Topics: Antipsychotic Agents; Antitussive Agents; Chemistry, Pharmaceutical; Codeine; Cough; Dextromoramide; Drug Therapy; Humans; Meperidine; Methadone; Morphine; Pharmacology; Phenothiazines; Phenylacetates; Piperazines; Piperidines; Research; Thiophenes

1963
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS.
    Pharmacological reviews, 1964, Volume: 16

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Meperidine; Methadone; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Oxymorphone; Pentazocine; Phenazocine; Substance-Related Disorders; Toxicology

1964
ANALGESICS FOR USE IN DENTAL PRACTICE.
    Journal of oral therapeutics and pharmacology, 1965, Volume: 1

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Azepines; Codeine; Dentistry; Dextropropoxyphene; Drug Therapy; Meperidine; Methadone; Phenacetin

1965

Trials

4 trial(s) available for methadone and meperidine

ArticleYear
The clinical testing of weak oral analgesics.
    Anaesthesia, 1974, Volume: 29, Issue:3

    Topics: Administration, Oral; Analgesics; Clinical Trials as Topic; Drug Evaluation; Humans; Meperidine; Methadone; Methods; Naphthaleneacetic Acids; Pain; Time Factors

1974
The prevention of analgesic-induced nausea and vomiting by cyclizine.
    The British journal of clinical practice, 1968, Volume: 22, Issue:9

    Topics: Analgesia; Clinical Trials as Topic; Codeine; Cyclizine; Female; Humans; Levorphanol; Male; Meperidine; Methadone; Nausea; Placebos; Vomiting

1968
Comparison of four narcotic analgesics for extradural analgesia.
    British journal of anaesthesia, 1982, Volume: 54, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Epidural Space; Female; Fentanyl; Hemodynamics; Humans; Injections; Male; Meperidine; Methadone; Middle Aged; Morphine; Pain, Postoperative; Respiration; Time Factors

1982
Ventilatory effects of morphine, pethidine and methadone in children.
    British journal of anaesthesia, 1993, Volume: 70, Issue:4

    Topics: Child; Child, Preschool; Depression, Chemical; Female; Humans; Male; Meperidine; Methadone; Morphine; Oxygen; Pain, Postoperative; Respiration; Tidal Volume; Time Factors

1993

Other Studies

215 other study(ies) available for methadone and meperidine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
From hit to lead. Combining two complementary methods for focused library design. Application to mu opiate ligands.
    Journal of medicinal chemistry, 2001, Oct-11, Volume: 44, Issue:21

    Topics: Animals; Cerebral Cortex; Combinatorial Chemistry Techniques; Humans; Imidazoles; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Radioligand Assay; Rats; Receptors, Opioid, mu; Solubility; Spiro Compounds; Structure-Activity Relationship

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of blockade of 5-hydroxytryptamine re-uptake on drug-induced antinociception in the rat.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:5

    Topics: Analgesics; Animals; Brain; Depression, Chemical; Male; Meperidine; Methadone; Morphine; Phenyl Ethers; Propylamines; Rats; Reaction Time; Serotonin

1976
Effects of narcotic analgesics on serotonin metabolism in brain of rats and mice.
    Japanese journal of pharmacology, 1976, Volume: 26, Issue:5

    Topics: Analgesics, Opioid; Animals; Atropine; Brain; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Mice; Mice, Inbred ICR; Morphine; Naloxone; Pargyline; Probenecid; Rats; Serotonin

1976
The effect of 6-hydroxydopamine on the antinociceptive action of analgesics in mice.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:5

    Topics: Analgesics, Opioid; Animals; Drug Interactions; Female; Hydroxydopamines; Injections, Intraventricular; Levorphanol; Meperidine; Methadone; Mice; Morphine; Pentazocine; Reaction Time; Time Factors

1977
Drug metabolism by the fetal stump-tailed monkey (Macaca arctoides). Hepatic microsomal N-demethylation and glucuronidation as measured by radiometric assays.
    Pharmacology, 1979, Volume: 18, Issue:5

    Topics: Animals; Animals, Newborn; Cytochrome P-450 Enzyme System; Gestational Age; Glucuronidase; Haplorhini; Liver; Macaca; Meperidine; Methadone; Microsomes, Liver; Morphine; Organ Size; Oxidoreductases, N-Demethylating; Proteins

1979
Dual action of morphine and related drugs on compulsive gnawing of rats.
    Psychopharmacologia, 1976, Volume: 46, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Compulsive Behavior; Female; Fenclonine; Humans; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Stereotyped Behavior; Thalamic Nuclei

1976
The effect of p-chlorophenylalanine on the pethidine- or methadone-induced decrease in locomotor activity of rats.
    European journal of pharmacology, 1976, Volume: 37, Issue:2

    Topics: Animals; Depression, Chemical; Fenclonine; Male; Meperidine; Methadone; Motor Activity; Rats; Time Factors

1976
Role of 5-hydroxytryptamine in morphine-, pethidine-, and methadone-induced hypothermia in rats at low ambient and room temperature.
    British journal of pharmacology, 1977, Volume: 60, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Cold Temperature; Depression, Chemical; Drug Interactions; Fenclonine; Male; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Temperature; Time Factors

1977
The effects of narcotic analgesics and narcotic antagonists on ganglionic transmission in the rat.
    Life sciences, 1976, Aug-01, Volume: 19, Issue:3

    Topics: Animals; Ganglia, Autonomic; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Stereoisomerism; Synaptic Transmission

1976
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
    Life sciences, 1975, Jul-01, Volume: 17, Issue:1

    Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Dexetimide; Dextromoramide; Dogs; Dopamine; Drug Combinations; Haloperidol; Humans; Meperidine; Methadone; Mice; Morphine; Phenoperidine; Pimozide; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome; Tranquilizing Agents; Vomiting

1975
Hepatic extraction of long- and short-acting narcotics in the isolated perfused rabbit liver.
    Gastroenterology, 1978, Volume: 75, Issue:1

    Topics: Animals; Biotransformation; Heroin; Liver; Liver Circulation; Meperidine; Methadone; Morphine; Narcotics; Rabbits; Time Factors

1978
Objective tests of analgesic drugs in ponies.
    American journal of veterinary research, 1979, Volume: 40, Issue:8

    Topics: Analgesics; Animals; Disease Models, Animal; Female; Fentanyl; Horse Diseases; Horses; Male; Meperidine; Methadone; Oxymorphone; Pain; Pentazocine; Xylazine

1979
Analysis of the bradykinin response in dogs and its antagonism by analgesic drugs.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 207, Issue:2

    Topics: Analgesics; Animals; Aspirin; Bradykinin; Dextroamphetamine; Dogs; Dose-Response Relationship, Drug; Female; Indomethacin; Male; Meperidine; Methadone; Phenylbutazone

1978
Cardiopulmonary effects of narcotic agonists and a partial agonist in horses.
    American journal of veterinary research, 1978, Volume: 39, Issue:10

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular System; Carotid Arteries; Heart Rate; Horses; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pentazocine; Respiration

1978
Meperidine effects on schedule-controlled responding.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 201, Issue:2

    Topics: Animals; Columbidae; Conditioning, Operant; Cyclazocine; Drug Interactions; Drug Tolerance; Male; Meperidine; Methadone; Morphine; Naloxone; Reaction Time; Reinforcement Schedule

1977
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1

    Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Injections, Intraperitoneal; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotics; Pentazocine; Substance Withdrawal Syndrome

1975
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on ganglionic transmission.
    Journal of autonomic pharmacology, 1992, Volume: 12, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Electric Stimulation; Ganglia, Sympathetic; In Vitro Techniques; Male; Meperidine; Methadone; Morphine; Naloxone; Rats; Rats, Inbred Strains; Synaptic Transmission

1992
[Iatrogenic addiction of pethidine: clinical feature and experience of detoxification].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1992, Volume: 25, Issue:2

    Topics: Adult; Clonidine; Female; Humans; Iatrogenic Disease; Male; Meperidine; Methadone; Substance-Related Disorders

1992
Histamine release induced by opioid analgesics: a comparative study using porcine mast cells.
    Agents and actions, 1991, Volume: 33, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Histamine Release; Hydromorphone; Kidney; Liver; Lung; Mast Cells; Meperidine; Methadone; Morphine; Myocardium; Oxycodone; Swine

1991
Evaluation of the transdermal route for administration of narcotic analgesics: human skin permeability studies of methadone and pethidine.
    Acta pharmaceutica Nordica, 1991, Volume: 3, Issue:3

    Topics: Administration, Cutaneous; Humans; Meperidine; Methadone; Skin Absorption

1991
[Narcotic abuse in Jylland. A study based on narcotics and deaths of addicts examined at the Institute of Forensic Medicine, University of Aarhus during the period 1981-1988. 2. Deaths among addicts].
    Ugeskrift for laeger, 1990, Apr-09, Volume: 152, Issue:15

    Topics: Adolescent; Adult; Alcoholic Intoxication; Amphetamine; Denmark; Dextropropoxyphene; Female; Heroin Dependence; Humans; Male; Meperidine; Methadone; Middle Aged; Opioid-Related Disorders; Substance-Related Disorders

1990
Intrathecal opioids, potency and lipophilicity.
    Pain, 1989, Volume: 36, Issue:1

    Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Endorphins; Injections, Spinal; Membrane Lipids; Meperidine; Methadone; Morphine; Morphine Derivatives; Nociceptors; Rats; Receptors, Opioid; Receptors, Opioid, mu; Solubility; Spinal Cord

1989
Fatal intoxications in the age group 15-34 years in Denmark in 1984 and 1985. A forensic study with special reference to drug addicts.
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1989, Volume: 103, Issue:2

    Topics: Adolescent; Adult; Analgesics, Opioid; Barbiturates; Cause of Death; Cross-Sectional Studies; Denmark; Dextropropoxyphene; Drug Overdose; Heroin; Humans; Incidence; Meperidine; Methadone; Morphine; Substance-Related Disorders

1989
Analeptic effect of opiate receptor agonists in rabbits.
    Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1

    Topics: Animals; Arousal; Brain; Central Nervous System Stimulants; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethylketocyclazocine; Etorphine; Male; Meperidine; Methadone; Morphine; Naltrexone; Narcotics; Phenazocine; Rabbits; Receptors, Opioid; Reflex

1985
5-HT-uptake inhibition potentiates antinociception induced by morphine, pethidine, methadone and ketobemidone in rats.
    Acta pharmacologica et toxicologica, 1985, Volume: 57, Issue:3

    Topics: Analgesics; Analgesics, Opioid; Animals; Brain; Citalopram; Drug Synergism; Male; Meperidine; Methadone; Morphine; Propylamines; Rats; Rats, Inbred Strains; Reaction Time; Serotonin; Serotonin Antagonists; Synaptosomes

1985
Maternal-fetal transfer of abused substances: pharmacokinetic and pharmacodynamic data.
    NIDA research monograph, 1985, Volume: 60

    Topics: Amphetamine; Animals; Cocaine; Dronabinol; Female; Fetus; Humans; Kinetics; Lysergic Acid Diethylamide; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Nicotine; Phencyclidine; Pregnancy; Substance-Related Disorders

1985
Combined use of detomidine with opiates in the horse.
    Equine veterinary journal, 1988, Volume: 20, Issue:5

    Topics: Animals; Behavior, Animal; Blood Pressure; Butorphanol; Heart Rate; Horses; Hypnotics and Sedatives; Imidazoles; Meperidine; Methadone; Morphine; Narcotics; Pulmonary Gas Exchange

1988
Mechanism for the opioid-induced twitch potentiations of frog's skeletal muscle.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:7

    Topics: Animals; Calcium; Dextrorphan; Etorphine; In Vitro Techniques; Meperidine; Methadone; Morphine; Muscle Contraction; Muscles; Narcotics; Rana pipiens; Stimulation, Chemical

1986
Morphine discrimination in the pigeon using a color tracking procedure.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Animals; Cocaine; Color; Columbidae; Cues; Cyclazocine; Dextroamphetamine; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Response; Male; Meperidine; Methadone; Morphine; Narcotics; Pentobarbital; Phencyclidine; Psychomotor Performance

1986
Displacement of the surface membrane bound calcium of the skeletal muscle fibers of the frog: effects of lanthanum and opioids.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:1

    Topics: Animals; Binding Sites; Calcium; Cell Membrane; In Vitro Techniques; Lanthanum; Meperidine; Methadone; Morphine; Muscles; Narcotics; Rana pipiens

1985
Simultaneous measurement of bupivacaine, etidocaine, lidocaine, meperidine, mepivacaine, and methadone.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:1

    Topics: Anesthetics, Local; Bupivacaine; Chromatography, Gas; Etidocaine; Humans; Lidocaine; Meperidine; Mepivacaine; Methadone

1986
Cross-sensitization to the excitatory effect of morphine in post-dependent rats.
    Neuropharmacology, 1985, Volume: 24, Issue:9

    Topics: Animals; Male; Meperidine; Methadone; Morphine; Morphine Dependence; Motor Activity; Pentazocine; Rats; Rats, Inbred Strains; Time Factors

1985
Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits.
    Life sciences, 1985, Dec-30, Volume: 37, Issue:26

    Topics: Animals; Biological Assay; Dextrorphan; Diazepam; Dose-Response Relationship, Drug; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Levorphanol; Male; Meperidine; Methadone; Nociceptors; Pentazocine; Pentobarbital; Proadifen; Rabbits; Time Factors

1985
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
The search for a better analgesic.
    Science (New York, N.Y.), 1973, Aug-03, Volume: 181, Issue:4098

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Heroin; Humans; Hydromorphone; Levorphanol; Meperidine; Methadone; Morphinans; Morphine Dependence; Structure-Activity Relationship

1973
Rapid methods of screening micro-quantities of abused drugs from urine samples for microcrystal tests.
    Clinical toxicology, 1973, Volume: 6, Issue:3

    Topics: Acids; Alkalies; Alkaloids; Chromatography, Thin Layer; Codeine; Crystallization; Crystallography; Heroin Dependence; Humans; Hydromorphone; Indicators and Reagents; Meperidine; Methadone; Methods; Morphine; Nicotine; Quinine; Substance-Related Disorders

1973
Contribution of 'receptor' affinity to analgesic potency.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: 1-Propanol; Analgesics; Animals; Binding, Competitive; Brain; Cyclopropanes; Fentanyl; Guinea Pigs; Hydromorphone; In Vitro Techniques; Injections, Intravenous; Levorphanol; Meperidine; Methadone; Morphinans; Morphine; Pentanols; Receptors, Drug

1974
[Analgesia in myocardial infarct].
    Zeitschrift fur Kardiologie, 1974, Volume: 63, Issue:12

    Topics: Analgesics; Diazepam; Heart; Hemodynamics; Heroin; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Myocardial Infarction; Nitrogen Oxides; Pain; Pentazocine; Respiration

1974
Antagonism of acute lethality of narcotic analgesics in aggregated and isolated mice by the central cholinomimetic action of pilocarpine.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 210, Issue:2

    Topics: Analgesics, Opioid; Animals; Atropine; Atropine Derivatives; Crowding; Depression, Chemical; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Motor Activity; Parasympathomimetics; Pentazocine; Pilocarpine; Social Isolation; Stimulation, Chemical; Time Factors

1974
[Ionization constants of several narcotic analgesics and their pain relieving activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:3

    Topics: Analgesics, Opioid; Benzilates; Chemical Phenomena; Chemistry, Physical; Codeine; Dextromoramide; Dimethylamines; Kinetics; Levorphanol; Meperidine; Methadone; Morphine; Muscle Relaxants, Central; Phenylacetates; Structure-Activity Relationship

1973
Urine screening techniques employed in the detection of users of narcotics and their correlation with the nalorphine test.
    Journal of forensic sciences, 1966, Volume: 11, Issue:2

    Topics: Amphetamine; California; Cocaine; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Nalorphine; Pupil; Substance-Related Disorders

1966
[Modifications of the contractility of the sphincter of Oddi under the influence of central analgesics].
    Revue internationale d'hepatologie, 1967, Volume: 17, Issue:1

    Topics: Ampulla of Vater; Amyl Nitrite; Atropine; Chlorpromazine; Cholecystectomy; Humans; Hydromorphone; Meperidine; Methadone; Procaine

1967
A method of identifying narcotic analgesics in human urine after therapeutic doses.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Alkaloids; Analgesics; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Humans; Hydromorphone; Ion Exchange; Levorphanol; Meperidine; Methadone; Methods; Morphine; Narcotics; Pentazocine

1970
Effects of opioid narcotic drugs on energy reserves of skeletal muscle. I. Glycogen.
    Biochemical pharmacology, 1974, Feb-01, Volume: 23, Issue:3

    Topics: Animals; Calcium; Carbon Radioisotopes; Diaphragm; Drug Tolerance; Energy Metabolism; Epinephrine; Glucose; Glycogen; Glycogen Synthase; In Vitro Techniques; Male; Meperidine; Methadone; Morphinans; Morphine; Muscles; Narcotics; Phosphoglucomutase; Phosphorylases; Propranolol; Rats; Time Factors

1974
[On the differential toxicity of drugs following subcutaneous, intragastric and intraduodenal application in rats].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Animals; Atropine; Duodenum; Epinephrine; Meperidine; Methadone; Parasympatholytics; Pentobarbital; Quaternary Ammonium Compounds; Rats; Scopolamine; Stomach; Xanthenes

1968
Interactions of some analgesics and antidepressants with phenelzine or reserpine in the mouse.
    Pharmacology, 1974, Volume: 12, Issue:1

    Topics: Alphaprodine; Analgesics; Animals; Antidepressive Agents; Body Temperature; Drug Interactions; Fenclonine; Hypothermia; Imipramine; Isonipecotic Acids; Lethal Dose 50; Male; Meperidine; Methadone; Mice; Pentazocine; Phenelzine; Reserpine; Time Factors

1974
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
    British journal of pharmacology, 1974, Volume: 51, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus

1974
Hyposensitivity to drugs induced by morphine and some related substances in the cat.
    British journal of pharmacology, 1970, Volume: 39, Issue:4

    Topics: Angiotensin II; Animals; Blood Pressure; Cats; Epinephrine; Female; Meperidine; Methadone; Morphine; Muscle, Smooth; Nalorphine; Nictitating Membrane; Norepinephrine; Tachyphylaxis; Uterus; Venous Pressure

1970
Analgesically active basic anilides: stereospecificity and structure of the basic group.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:1

    Topics: Analgesics; Anilides; Animals; Behavior, Animal; Chemistry, Organic; Meperidine; Methadone; Mice; Organic Chemistry Phenomena; Sensory Receptor Cells

1967
[On the inhibitory effect of kinins on isolated intestinal sections].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie und experimentelle Pathologie, 1966, Volume: 254, Issue:3

    Topics: Anesthetics, Local; Animals; Atropine; Bradykinin; Caffeine; Duodenum; Ganglionic Blockers; Guanethidine; Ileum; Jejunum; Kallidin; Meperidine; Methadone; Morphine; Phenylbutazone; Rabbits

1966
Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19

    Topics: Adult; Amines; Amphetamine; Appetite Depressants; Benzphetamine; Biological Transport; Chlorpheniramine; Chlorphentermine; Ephedrine; Fenfluramine; Furans; Humans; Hydrogen-Ion Concentration; Lidocaine; Male; Membranes; Meperidine; Mephentermine; Methadone; Models, Biological; Morpholines; Mouth; Nicotine; Phenethylamines; Phenmetrazine; Phenylpropanolamine

1967
[Further studies on the effect of various drugs on the respiration].
    Allergie und Asthma, 1968, Volume: 14, Issue:5

    Topics: Antifibrinolytic Agents; Benzoates; Central Nervous System Stimulants; Chlorpromazine; Humans; Meperidine; Methadone; Phenobarbital; Pulmonary Heart Disease; Respiration; Theobromine

1968
Central and peripheral monoaminergic membrane-pump blockade by some addictive analgesics and antihistamines.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:7

    Topics: 5-Hydroxytryptophan; Amines; Analgesics; Animals; Biological Transport, Active; Chlorpheniramine; Diphenhydramine; Histamine H1 Antagonists; Meperidine; Methadone; Mice; Neurons; Nialamide; Norepinephrine; Serotonin; Tripelennamine

1969
Screening method for detection of drugs of abuse in human urine.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Alkaloids; Amphetamine; Analgesics; Barbiturates; Chlorpheniramine; Chromatography; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonists; Hot Temperature; Humans; Indicators and Reagents; Isonipecotic Acids; Meperidine; Methadone; Methods; Morphinans; Morphine; Pentazocine; Phenacetin; Phenothiazines; Quinidine; Substance-Related Disorders; Ultraviolet Rays

1971
Liquid-solid extraction of lyophilized biological material for forensic analysis. I. Application to urine samples for detection of drugs of abuse.
    Journal of chromatography, 1971, Dec-23, Volume: 63, Issue:2

    Topics: Acetates; Antidepressive Agents; Barbiturates; Chromatography, Thin Layer; Forensic Medicine; Freeze Drying; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Meperidine; Methadone; Methods; Morphine; Substance-Related Disorders

1971
Effects of narcotic analgesics on contractions of the chick isolated, innervated oesophagus.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:9

    Topics: Acetylcholine; Analgesics; Animals; Chickens; Cyclazocine; Dextropropoxyphene; Electric Stimulation; Esophagus; Heroin; In Vitro Techniques; Meperidine; Methadone; Morphinans; Morphine; Muscle Contraction; Nalorphine; Pentazocine; Phenazocine; Serotonin; Tachyphylaxis; Time Factors

1972
Optimization of extraction and separation of narcotics from urine.
    Clinical biochemistry, 1974, Volume: 7, Issue:3

    Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors

1974
Effect of acutely administered analgesic drugs on rat brain serotonin turnover.
    European journal of pharmacology, 1974, Volume: 29, Issue:2

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Clomipramine; Dopamine; Hydroxyindoleacetic Acid; Kinetics; Male; Meperidine; Methadone; Morphine; Naloxone; Nialamide; Norepinephrine; Pargyline; Pentazocine; Rats; Serotonin; Stimulation, Chemical; Tranylcypromine; Tryptophan

1974
Interactions of narcotics and their antagonists with human serum esterase. V: Hidden agonistic effects.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Dextropropoxyphene; Dose-Response Relationship, Drug; Esterases; Humans; Hydrolysis; In Vitro Techniques; Kinetics; Meperidine; Methadone; Morphinans; Nalorphine; Narcotic Antagonists; Narcotics; Piperidines; Procaine; Protein Binding; Stimulation, Chemical

1974
Induction of physical dependence on morphine, codeine and meperidine in the rat by continuous infusion.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Codeine; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Injections, Intraperitoneal; Male; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorphine; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Vocalization, Animal

1974
Studies on physical dependence inducible by hours exposure of mice to morphine.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:6

    Topics: Analgesia; Animals; Behavior, Animal; Body Weight; Drug Tolerance; Humans; Infusions, Parenteral; Injections; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Pentazocine; Substance Withdrawal Syndrome; Time Factors

1972
A scoring system for abstinence syndrome in morphine dependent mice and application to evaluate morphine type dependence liability of drugs.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:5

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Humans; Male; Meperidine; Methadone; Mice; Morphine Dependence; Phenobarbital; Substance Withdrawal Syndrome; Time Factors

1973
Effects of acutely administered analgesic drugs on rat brain 5-hydroxytryptamine turnover.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Morphine; Pargyline; Pentazocine; Probenecid; Rats; Serotonin

1972
[Clinical pharmacology of narcotics. II].
    Hippokrates, 1972, Volume: 43, Issue:4

    Topics: Chemical Phenomena; Chemistry; Hallucinogens; Humans; Lysergic Acid Diethylamide; Meperidine; Methadone; Morphinans; Morphine Dependence; Pentazocine; Substance-Related Disorders

1972
Acute effects of narcotic analgesics on behavioral arousal in the rat.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:6

    Topics: Analgesics; Animals; Arousal; Dose-Response Relationship, Drug; Levorphanol; Locomotion; Male; Meperidine; Methadone; Methyltyrosines; Morphine; Narcotics; Pentazocine; Rats; Time Factors

1973
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2

    Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium

1973
Agonistic properties of narcotic analgesics and antagonists on the electroencephalogram and behavior in the rat and their reversal by naloxone.
    Neuropharmacology, 1973, Volume: 12, Issue:7

    Topics: Analgesics; Animals; Behavior, Animal; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Female; Meperidine; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Sleep; Time Factors

1973
Some behavioral and EEG effects of a new analgesic agent (viminol) in comparison with morphine in rats.
    European journal of pharmacology, 1973, Volume: 23, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Benzyl Compounds; Butylamines; Conditioning, Operant; Dose-Response Relationship, Drug; Electroencephalography; Ethanolamines; Humans; Lethal Dose 50; Locomotion; Male; Meperidine; Meprobamate; Methadone; Morphine; Pyrroles; Rats; Substance-Related Disorders; Time Factors

1973
Effect of stimulus intensity on the potency of some analgetic agents.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:1

    Topics: Analgesics; Animals; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Levorphanol; Male; Meperidine; Methadone; Mice; Mice, Inbred Strains; Naloxone; Pentazocine; Physical Stimulation; Reaction Time; Seizures; Time Factors; Tremor

1973
[Social conditions and use of drugs in a group of young addicts in Oslo].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: Administration, Oral; Adolescent; Adult; Alcoholism; Amphetamine; Cannabis; Educational Status; Family; Female; Humans; Injections, Intravenous; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Morphine; Narcotics; Norway; Opium; Phenmetrazine; Social Problems; Socioeconomic Factors; Substance-Related Disorders; Time Factors; Unemployment

1973
Effect of midbrain raphe lesion on the antinociceptive action of morphine and other analgesics in rats.
    Psychopharmacologia, 1973, Dec-20, Volume: 33, Issue:4

    Topics: Animals; Codeine; Dextropropoxyphene; Meperidine; Mesencephalon; Methadone; Morphine; Rats; Serotonin

1973
[Ionization constants of several narcotic analgesics and their pain relieving action].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:1

    Topics: Analgesics; Codeine; Dextromoramide; Dimethylamines; Diphenylacetic Acids; Ethers, Cyclic; Hydrogen-Ion Concentration; Ions; Kinetics; Levorphanol; Mathematics; Meperidine; Methadone; Morphinans; Morphine; Narcotics; Piperidines

1973
Effects of narcotic analgesics and their antagonists on the rabbit isolated heart and its adrenergic nerves.
    British journal of pharmacology, 1973, Volume: 49, Issue:4

    Topics: Animals; Autonomic Nervous System; Drug Interactions; Electric Stimulation; Female; Fentanyl; Heart; Heart Rate; In Vitro Techniques; Levallorphan; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Perfusion; Rabbits; Secretory Rate; Sympathetic Nervous System

1973
Anti-nociceptive activity of some thiophthalanes with morphine-like properties.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:3

    Topics: Analgesia; Analgesics; Animals; Bridged-Ring Compounds; Depression, Chemical; Dextropropoxyphene; Dimethylamines; Electric Stimulation; Ketones; Male; Meperidine; Methadone; Mice; Morphine; Pain; Piperidines; Thiophenes

1973
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders

1974
Routine use of a flexible gas chromatograph-mass spectrometer-computer system to identify drugs and their metabolites in body fluids of overdose victims.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Computers; Evaluation Studies as Topic; Humans; Infant; Infant, Newborn; Male; Mass Spectrometry; Meperidine; Methadone; Methaqualone; Methods; Substance-Related Disorders

1974
Thiazine dye antagonism of opioid lethality in mice.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3

    Topics: Animals; Codeine; Dextropropoxyphene; Drug Synergism; Hexobarbital; Lethal Dose 50; Levorphanol; Male; Meperidine; Methadone; Methylene Blue; Mice; Morphinans; Morphine; Sleep; Thiazines; Time Factors; Tolonium Chloride

1974
Chemical evaluation of 'drug cocktails' in autopsy specimens.
    Journal of chromatographic science, 1974, Volume: 12, Issue:5

    Topics: Adult; Amphetamine; Autopsy; Barbiturates; Body Fluids; Forensic Medicine; Hallucinogens; Humans; Hypnotics and Sedatives; Levallorphan; Male; Meperidine; Methadone; Methaqualone; Morphinans; Morphine; Pharmaceutical Preparations; Poisoning; Substance-Related Disorders; Tissue Extracts

1974
New molecular complexes of methadone, its congeners and some other opiates with copper and iron.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:2

    Topics: Chemical Phenomena; Chemistry; Chlorides; Codeine; Copper; Crystallization; Dextropropoxyphene; Drug Stability; Heroin Dependence; Humans; Iron; Meperidine; Methadone; Solutions; Stereoisomerism

1974
Methadone maintenance therapy for heroin addiction. Some surgical considerations.
    American journal of surgery, 1972, Volume: 123, Issue:3

    Topics: Adult; Cardiac Surgical Procedures; Curettage; Dextropropoxyphene; Dilatation; Female; Fracture Fixation; Heroin; Humans; Hysterectomy; Male; Meperidine; Methadone; Orthopedics; Pain; Pentazocine; Substance Withdrawal Syndrome; Substance-Related Disorders; Surgery, Oral; Surgical Procedures, Operative

1972
Mini thin-layer chromatography in the detection of narcotics in urine from subjects on a methadone maintenance program.
    Journal of chromatography, 1972, Mar-01, Volume: 65, Issue:3

    Topics: Chromatography, Thin Layer; Codeine; Colorimetry; Humans; Meperidine; Methadone; Methods; Morphine; Narcotics; Substance-Related Disorders

1972
Treatment of morphine-type dependence by withdrawal methods.
    JAMA, 1972, Mar-20, Volume: 219, Issue:12

    Topics: Barbiturates; Female; Heroin; Hospitalization; Humans; Male; Meperidine; Methadone; Morphine; Pregnancy; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Tranquilizing Agents

1972
Action of picric acid on the effects of some drugs acting on the central nervous system, with special reference to opioids.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:2

    Topics: Amphetamine; Analgesia; Analgesics; Animals; Benzimidazoles; Drug Synergism; Female; Male; Meperidine; Methadone; Mice; Microsomes, Liver; Morphine; Pentazocine; Pentylenetetrazole; Picrates; Seizures; Sleep; Sodium Salicylate

1971
Some clinical impressions of droperidol used as premedication in children.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971, Oct-02, Volume: 45, Issue:38

    Topics: Adult; Atropine; Benperidol; Child; Child, Preschool; Drug Combinations; Drug Synergism; Humans; Infant; Meperidine; Methadone; Postoperative Care; Premedication; Preoperative Care; Promethazine; Scopolamine; Trimeprazine

1971
Effects of narcotic analgesics and antagonists on the in vivo release of acetylcholine from the cerebral cortex of the cat.
    British journal of pharmacology, 1971, Volume: 43, Issue:1

    Topics: Acetylcholine; Analgesia; Analgesics; Animals; Bridged-Ring Compounds; Cats; Cerebral Cortex; Chlorpromazine; Codeine; Dextropropoxyphene; Female; Furans; Ketones; Levallorphan; Male; Meperidine; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenanthrenes

1971
An ultra rapid method for the extraction of drugs from biological fluids.
    Journal of chromatography, 1971, Dec-23, Volume: 63, Issue:2

    Topics: Amphetamine; Centrifugation; Chromatography, Gas; Chromatography, Thin Layer; Humans; Lipids; Meperidine; Methadone; Methamphetamine; Methods; Solubility; Solvents; Substance-Related Disorders; Time Factors

1971
[Studies of the toxicity of drugs in subcutaneous, intragastric and intraduodenal administration in rats].
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 180, Issue:1

    Topics: Animals; Atropine; Epinephrine; Gallamine Triethiodide; Isoproterenol; Meperidine; Methadone; Norepinephrine; Papaverine; Parasympatholytics; Propantheline; Quaternary Ammonium Compounds; Rats; Scopolamine; Sympathomimetics; Synephrine; Xanthenes

1969
[Cause and treatment of spasticity following halothane anesthesia].
    Der Anaesthesist, 1969, Volume: 18, Issue:8

    Topics: Adult; Analgesics; Anesthesia, Inhalation; Benperidol; Body Temperature; Diazepam; Halothane; Humans; Meperidine; Methadone; Postoperative Complications; Promazine; Promethazine; Shivering; Spasm

1969
A quantitative method for the assessment of physical dependence on narcotic analgesics in mice.
    British journal of pharmacology, 1969, Volume: 37, Issue:2

    Topics: Animals; Humans; Meperidine; Methadone; Methods; Mice; Morphine Dependence; Motor Activity; Nalorphine; Substance Withdrawal Syndrome; Substance-Related Disorders

1969
Studies of drugs given before anaesthesia. XIX. The opiates.
    British journal of anaesthesia, 1970, Volume: 42, Issue:1

    Topics: Analgesics; Diazepam; Female; Fentanyl; Heroin; Humans; Levorphanol; Male; Meperidine; Methadone; Morphine; Papaverine; Phenazocine; Preanesthetic Medication; Vomiting

1970
Action of codeine, pethidine and methadone on the operant behavior of the rat.
    Psychopharmacologia, 1970, Volume: 17, Issue:1

    Topics: Animals; Avoidance Learning; Codeine; Conditioning, Operant; Depression, Chemical; Male; Meperidine; Methadone; Rats; Reinforcement, Psychology

1970
Oxygen, carbon dioxide, and pH responses in arterial blood of dogs given analgesic, neuroleptanalgesic, and ataractic agents.
    Journal of the American Veterinary Medical Association, 1970, May-15, Volume: 156, Issue:10

    Topics: Analgesics; Animals; Arteries; Atropine; Carbon Dioxide; Dogs; Hydrogen-Ion Concentration; Meperidine; Methadone; Morphine; Narcotics; Neuroleptanalgesia; Oxygen; Pentazocine; Respiration; Respiratory Function Tests; Tranquilizing Agents

1970
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhydramine; Histamine; Humans; Meperidine; Meprobamate; Methadone; Methods; Morphine Dependence; Pentazocine; Pyrrolidines; Rats; Salicylates; Serotonin; Substance Withdrawal Syndrome

1970
The "staircase maze" and the "simple staircase" in the analysis of the psychopharmacological action of CNS depressants.
    Pharmacology, 1970, Volume: 4, Issue:3

    Topics: Analgesics; Animals; Barbiturates; Behavior, Animal; Central Nervous System; Chlorpromazine; Hydroxyzine; Hypnotics and Sedatives; Meperidine; Methadone; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Rats; Reserpine; Tranquilizing Agents

1970
Secondary drug use among heroin users.
    The International journal of the addictions, 1970, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Aged; Amphetamine; Barbiturates; Cannabis; Cocaine; Crime; Educational Status; Ethnicity; Heroin; Humans; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Middle Aged; Morphine Dependence; New York; Opium; Substance-Related Disorders

1970
[Acute tolerance to continuous subcutaneous infusion of morphine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Sep-20, Volume: 66, Issue:5

    Topics: Analgesia; Animals; Drug Tolerance; Heart Rate; Injections, Subcutaneous; Male; Meperidine; Methadone; Mice; Morphine

1970
Pharmacology of narcotics and antagonists as related to drug abuse.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Codeine; Heroin; Humans; Levallorphan; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorphine; Narcotic Antagonists; Stereoisomerism; Substance-Related Disorders

1971
[The effects of spasmolytics on the mechanical and electrical activity of isolated rat uterus].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:7

    Topics: Acetylcholine; Action Potentials; Animals; Depression, Chemical; Female; In Vitro Techniques; Meperidine; Methadone; Morphine; Muscle Contraction; Muscles; Papaverine; Rats; Scopolamine; Stimulation, Chemical; Uterus

1967
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
    Journal of chromatography, 1969, May-20, Volume: 41, Issue:3

    Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine

1969
The specific assay of basic drugs in urine by CM-cellulose chromatography using continuous drug-dye complex extraction as a detection system.
    Journal of chromatography, 1969, Aug-05, Volume: 43, Issue:1

    Topics: Amphetamine; Buffers; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Coloring Agents; Cyclizine; Ephedrine; Guanethidine; Guanidines; Hydrogen-Ion Concentration; Meperidine; Methadone; Morphine; Spectrophotometry; Strychnine

1969
The responses of the terminal bile duct to morphine and morphine-like drugs.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 149, Issue:3

    Topics: Ampulla of Vater; Animals; Bile Ducts; Cats; Cattle; Dextromoramide; Dogs; In Vitro Techniques; Levorphanol; Meperidine; Methadone; Morphine; Tachyphylaxis

1965
The analgesic effect of opiate-opiate antagonist combinations in the rat.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 149, Issue:3

    Topics: Analgesics; Animals; Levallorphan; Meperidine; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Phenazocine; Rats; Sensory Receptor Cells

1965
Release of intestinal 5-hydroxytryptamine by morphine and related agents.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Calcium; Cocaine; Dogs; Female; Guinea Pigs; Ileum; Injections, Intravenous; Intestinal Mucosa; Intestines; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Nicotine; Rats; Reserpine; Serotonin; Tachyphylaxis; Uterus

1967
Oxygen consumption in the new-born rat and the effects of maternally administered analgesics.
    British journal of pharmacology and chemotherapy, 1967, Volume: 30, Issue:3

    Topics: Analgesics; Animals; Animals, Newborn; Female; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Oxygen Consumption; Pregnancy; Rats

1967
Antagonistic action of tolazoline upon the analgesic effect of some morphine analogues.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 16, Issue:3

    Topics: Analgesia; Animals; Drug Antagonism; Meperidine; Methadone; Morphine; Phenazocine; Rats; Tolazoline

1967
[Pain-relieving agents. 2].
    Sykepleien, 1980, May-20, Volume: 67, Issue:9

    Topics: Analgesics; Analgesics, Opioid; Drug Tolerance; Humans; Meperidine; Methadone; Morphine; Morphine Derivatives; Substance-Related Disorders

1980
Comparative cardiac contractile actions of six narcotic analgesics: morphine, meperidine, pentazocine, fentanyl, methadone and l-alpha-acetylmethadol (LAAM).
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:1

    Topics: Analgesics, Opioid; Animals; Cats; Depression, Chemical; Drug Interactions; Fentanyl; Meperidine; Methadone; Methadyl Acetate; Morphine; Myocardial Contraction; Naloxone; Pentazocine; Stimulation, Chemical

1980
Opiates and thermoregulation in mice. I. Agonists.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2

    Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone

1980
Continuous naloxone infusion for opiate poisoning in infancy.
    The Journal of pediatrics, 1984, Volume: 105, Issue:4

    Topics: Humans; Infant; Infant, Newborn; Infusions, Parenteral; Male; Meperidine; Methadone; Naloxone; Poisoning

1984
Annual report: biological evaluation of compounds for their dependence liability. IV. Drug testing program of the Committee on Problems of Drug, Dependence, Inc. (1980).
    NIDA research monograph, 1981, Volume: 34

    Topics: Analgesics; Animals; Benzomorphans; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Drug Evaluation; Guinea Pigs; Humans; Meperidine; Methadone; Morphinans; Morphine; National Institutes of Health (U.S.); Rats; Research Support as Topic; Spectrophotometry, Infrared; Substance-Related Disorders; United States

1981
Attenuation of the behavioral effects of meperidine and normeperidine by daily administration of diazepam.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:1

    Topics: Animals; Columbidae; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Male; Meperidine; Methadone; Morphine; Pentobarbital

1983
Effect of spasmolytic analgesic drugs on the motility patterns of the equine small intestine.
    Research in veterinary science, 1983, Volume: 34, Issue:3

    Topics: Acepromazine; Analgesics; Animals; Butylscopolammonium Bromide; Colic; Dipyrone; Dogs; Drug Combinations; Electrophysiology; Gastrointestinal Motility; Horses; Intestinal Diseases; Intestine, Small; Male; Meperidine; Methadone; Parasympatholytics

1983
Effect of morphine and morphine-like drugs on carbachol-induced fighting in cats.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:2

    Topics: Aggression; Agonistic Behavior; Animals; Carbachol; Cats; Female; Humans; Injections, Intraventricular; Male; Meperidine; Methadone; Morphine

1982
The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia.
    Pain, 1982, Volume: 12, Issue:4

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Epidural Space; Female; Fentanyl; Lipids; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Nociceptors; Pain; Reflex; Skin; Time Factors

1982
Motility response of rats to chronic constant-dose treatment with narcotics.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:3

    Topics: Animals; Male; Meperidine; Methadone; Morphine; Motor Activity; Narcotics; Pentazocine; Rats; Rats, Inbred Strains; Time Factors

1982
Inhibition by morphine and morphine-like drugs of nicotine-induced emesis in cats.
    Brain research bulletin, 1981, Volume: 6, Issue:5

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Emetics; Female; Injections, Intraventricular; Male; Meperidine; Methadone; Morphine; Nicotine; Vomiting

1981
Ketobemidone, methadone and pethidine are non-competitive N-methyl-D-aspartate (NMDA) antagonists in the rat cortex and spinal cord.
    Neuroscience letters, 1995, Mar-10, Volume: 187, Issue:3

    Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Meperidine; Methadone; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord

1995
Disappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists.
    Pain, 1994, Volume: 59, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Child; Delayed-Action Preparations; Female; Humans; Hyperalgesia; Male; Meperidine; Methadone; Middle Aged; Morphine; Myoclonus; Narcotics; Neoplasms; Pain; Sufentanil

1994
Interaction between ethanol and opioids in a protozoan assay.
    Human & experimental toxicology, 1994, Volume: 13, Issue:3

    Topics: Animals; Dextropropoxyphene; Drug Interactions; Ethanol; Meperidine; Methadone; Movement; Narcotics; Tetrahymena pyriformis

1994
Deaths among drug addicts in Denmark in 1987-1991.
    Forensic science international, 1994, Aug-10, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Alcoholism; Amphetamine; Analgesics, Opioid; Barbiturates; Cannabis; Cause of Death; Denmark; Dextropropoxyphene; Female; Heroin; Humans; Male; Meperidine; Methadone; Morphine; Substance-Related Disorders; Suicide; Survival Rate

1994
Drug-related deaths during the 1980s. A comparative study of drug addict deaths examined at the institutes of forensic medicine in Aarhus, Denmark and Oslo, Norway.
    International journal of legal medicine, 1993, Volume: 106, Issue:1

    Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Cause of Death; Cross-Cultural Comparison; Cross-Sectional Studies; Denmark; Dextropropoxyphene; Drug Overdose; Female; Heroin Dependence; Humans; Illicit Drugs; Incidence; Male; Meperidine; Methadone; Morphine Dependence; Norway; Psychotropic Drugs; Substance-Related Disorders; Suicide; Urban Population

1993
Legal opioid consumption in Denmark 1981-1993.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:5

    Topics: Analgesia; Analgesics, Opioid; Buprenorphine; Denmark; Humans; Legislation, Drug; Meperidine; Methadone; Morphine

1995
International opioid consumption.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:1 Pt 2

    Topics: Analgesics, Opioid; Denmark; Drug Utilization; Humans; Meperidine; Methadone; Morphine; Pain

1997
[Changes in the pattern of opioid analgesic consumption in Spain].
    Medicina clinica, 1997, Sep-13, Volume: 109, Issue:8

    Topics: Administration, Oral; Administration, Rectal; Analgesics, Opioid; Buprenorphine; Codeine; Databases as Topic; Dextropropoxyphene; Drug Prescriptions; Humans; Injections, Intravenous; Linear Models; Meperidine; Methadone; Morphine; Pentazocine; Spain; Tilidine; Tramadol

1997
Drugs for pain.
    The Medical letter on drugs and therapeutics, 1998, Aug-14, Volume: 40, Issue:1033

    Topics: Acetaminophen; Administration, Oral; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Aspirin; Constipation; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Tolerance; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Ketorolac; Levorphanol; Meperidine; Methadone; Morphine; Narcotic Antagonists; Narcotics; Pain; Tolmetin; Tramadol

1998
Opioid consumption in Spain--the significance of a regulatory measure.
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:9

    Topics: Analgesics, Opioid; Drug and Narcotic Control; Drug Utilization; Fentanyl; Humans; Meperidine; Methadone; Morphine; Regression Analysis; Spain; Tilidine

1999
Solid-phase microextraction for the determination of pethidine and methadone in human urine using gas chromatography with nitrogen-phosphorus detection.
    The Analyst, 1999, Volume: 124, Issue:9

    Topics: Chromatography, Gas; Humans; Meperidine; Methadone; Narcotics

1999
Trends in licit opioid use in Australia, 1984-1998: comparative analysis of international and jurisdictional data.
    The Medical journal of Australia, 2000, Nov-20, Volume: 173, Issue:10

    Topics: Australia; Developed Countries; Drug Utilization; Humans; Meperidine; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Practice Patterns, Physicians'

2000
Liquid-phase microextraction of protein-bound drugs under non-equilibrium conditions.
    The Analyst, 2002, Volume: 127, Issue:5

    Topics: Amphetamine; Haloperidol; Humans; Meperidine; Methadone; Microchemistry; Pharmaceutical Preparations; Promethazine; Proteins

2002
[The new central analgesics].
    Praxis, 1952, Oct-02, Volume: 41, Issue:40

    Topics: Analgesics; Humans; Meperidine; Methadone; Morphinans

1952
Action of analgesic drugs morphine, meperidine, methadone on rotatory nystagmus in the rabbit.
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 107, Issue:2

    Topics: Analgesics; Animals; Meperidine; Methadone; Morphine; Nystagmus, Pathologic; Rabbits

1953
The chemistry of drugs of addiction.
    The American journal of medicine, 1953, Volume: 14, Issue:5

    Topics: Barbiturates; Cannabis; Humans; Hydromorphone; Meperidine; Methadone; Morphine Derivatives

1953
Clinical characteristics of addictions.
    The American journal of medicine, 1953, Volume: 14, Issue:5

    Topics: Barbiturates; Cannabis; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Substance-Related Disorders

1953
[Contribution to the demonstration of dolantin, polamidon and pervitin].
    Deutsche Zeitschrift fur die gesamte gerichtliche Medizin, 1952, Volume: 41, Issue:4-5

    Topics: Ephedrine; Meperidine; Methadone

1952
[Microscopical detection of morphine-like compounds].
    Arzneimittel-Forschung, 1953, Volume: 3, Issue:1

    Topics: Analgesics; Meperidine; Methadone; Morphine

1953
Analgesics and enzymes of the cytochrome chain.
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 108, Issue:3

    Topics: Analgesics; Brain; Cytochromes; Meperidine; Methadone; Morphine; Myocardium; Oxidoreductases

1953
[Methadon and pathidine derivatives, hazards in public sale, heptane].
    Revista de la Asociacion Medica Argentina, 1953, Volume: 67, Issue:747-748

    Topics: Analgesics; Behavior, Addictive; Commerce; Heptanes; Humans; Meperidine; Methadone; Substance-Related Disorders

1953
[Effect of drugs on the metabolism of pyruvate in fetuses and young animals. II. Morphine and synthetic morphine simulants].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:4

    Topics: Animals; Central Nervous System; Fetus; Liver; Meperidine; Methadone; Morphine; Pyruvates; Pyruvic Acid

1953
The depression of respiration by the opiates and its antagonism by nalorphine.
    Proceedings of the Royal Society of Medicine, 1953, Volume: 46, Issue:11

    Topics: Analgesics, Opioid; Depression; Depressive Disorder; Humans; Meperidine; Methadone; Morphine; Nalorphine; Respiration

1953
Synthetic substances with morphine-like effect; chemical aspects.
    Bulletin of the World Health Organization, 1954, Volume: 10, Issue:6

    Topics: Meperidine; Methadone; Morphine Derivatives

1954
[The effect of morphine, pethidine and methadon on peristaltic activity of intestines].
    Acta medica Iugoslavica, 1954, Volume: 8, Issue:2

    Topics: Intestines; Meperidine; Methadone; Morphine; Peristalsis

1954
[Some phenomena of synergism. I. Associations of analgesics and of a spasmolytic considered as their structural analog].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1955, Volume: 149, Issue:3-4

    Topics: Analgesics; Cardiovascular Agents; Inorganic Chemicals; Meperidine; Methadone; Muscle Relaxants, Central; Parasympatholytics

1955
Effect of adrenaline on the analgesic response of mice to morphine and related drugs.
    Archives internationales de pharmacodynamie et de therapie, 1955, Nov-01, Volume: 104, Issue:1

    Topics: Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Animals; Epinephrine; Meperidine; Methadone; Mice; Morphine; Pain Management

1955
Drug addiction and other considerations in the management of pain with narcotic drugs.
    Proceedings of the staff meetings. Mayo Clinic, 1957, Feb-06, Volume: 32, Issue:3

    Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narcotics; Pain; Substance-Related Disorders

1957
The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum.
    British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:1

    Topics: Acetylcholine; Codeine; Drug Tolerance; Guinea Pigs; Heroin; Ileum; Intestines; Meperidine; Methadone; Morphine; Nalorphine

1957
[Action of various synthetic analgesics in comparison with morphine & its derivatives].
    Pharmazeutische Zentralhalle fur Deutschland, 1957, Volume: 96, Issue:4

    Topics: Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Ephedrine; Meperidine; Methadone; Morphine; Pain Management

1957
A new series of potent analgesics: dextro 2:2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine and related basic amides. II. Comparative analgesic activity, acute toxicity and tolerance development in rats for R875, morphine, pethidine and methadone.
    The Journal of pharmacy and pharmacology, 1958, Volume: 10, Issue:1

    Topics: Amides; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Biphenyl Compounds; Drug Tolerance; Meperidine; Methadone; Morphine; Rats

1958
A study of the selective antagonism by N-allylnormorphine against meperidine, methadone, and morphine.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1958, Volume: 47, Issue:5

    Topics: Meperidine; Methadone; Morphine; Nalorphine

1958
[Proposal to the supplement of the 6th edition of the German Pharmacopeia. 6. Pethidin hydrochloride & methadon hydrochloride].
    Pharmazeutische Zentralhalle fur Deutschland, 1958, Volume: 97, Issue:6

    Topics: Dietary Supplements; Ethnicity; Humans; Meperidine; Methadone

1958
[Proposals for the supplement to the 6th edition of the German pharmacopeia. 6. Pethidine hydrochloride & methandon hydrochloride].
    Die Pharmazie, 1958, Volume: 13, Issue:10

    Topics: Dietary Supplements; Ethnicity; Humans; Meperidine; Methadone

1958
Comparative effects of analgesics on pain threshold, respiratory frequency and gastrointestinal propulsion.
    British journal of pharmacology and chemotherapy, 1959, Volume: 14, Issue:1

    Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antipyretics; Cell Respiration; Codeine; Dextromoramide; Gastrointestinal Tract; Guinea Pigs; Meperidine; Methadone; Morphine; Nalorphine; Pain; Pain Threshold; Rats; Respiration; Respiratory Rate

1959
Multiple toe-pinch method for testing analgesic drugs.
    British journal of pharmacology and chemotherapy, 1961, Volume: 17

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Chlorpromazine; Codeine; Guinea Pigs; Humans; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Morphine; Nalorphine; Phencyclidine; Phthalic Acids; Rats; Toes

1961
[The effect of various pharmacological agents (amphetamine, cocaine, caffeine, hexobarbital, meprobamate, morphine, dextromoramide, 1-methadone, pethidine and CT 3570) on the time of exhaustion and behavior of animals swimming at 20 degrees C].
    Medicina experimentalis : International journal of experimental medicine, 1960, Volume: 2

    Topics: Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior; Caffeine; Central Nervous System Stimulants; Cocaine; Dextromoramide; Hexobarbital; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed

1960
The control of injections and other pharmaceutical preparations by means of U.V. spectrophotometry as a standard analytical tool. VI. Spectrophotometric assay of atropine sulfate, pethidine hydrochloride and methadone hydrochloride (Symoron).
    Pharmaceutisch weekblad, 1961, Jan-21, Volume: 96

    Topics: Atropine; Biological Assay; Injections; Meperidine; Methadone; Spectrophotometry

1961
[Determination of methadone and pethidine in some galenical preparations. 2. Suppositories and injectables].
    Pharmaceutica acta Helvetiae, 1961, Volume: 36

    Topics: Injections; Meperidine; Methadone; Pessaries; Suppositories

1961
Cross-cellular adaptation to methadone and meperidine in cerebral cortical slices from morphinized rats.
    The Journal of pharmacology and experimental therapeutics, 1962, Volume: 135

    Topics: Animals; Cerebral Cortex; Meperidine; Methadone; Morphine; Rats

1962
Analgesia in electromyography.
    Archives of physical medicine and rehabilitation, 1963, Volume: 44

    Topics: Analgesia; Electromyography; Humans; Meperidine; Methadone; Pain; Pain Management; Promethazine

1963
[Behavior modifiers inthe study of bile ducts. (Combined action of morphine substances and cholecystokinin)].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1963, Volume: 44

    Topics: Ampulla of Vater; Bile Ducts; Cholecystokinin; Codeine; Dextromoramide; Hydromorphone; Meperidine; Methadone; Morphine; Opium

1963
A DIRECT TITRIMETRIC METHOD FOR THE DETERMINATION OF SOME ORGANIC BASES IN PHARMACEUTICAL PREPARATIONS.
    The Journal of pharmacy and pharmacology, 1963, Volume: 15

    Topics: Atropine; Chemistry, Pharmaceutical; Codeine; Meperidine; Methadone; Pharmacy; Research

1963
[THE INHIBITION OF MORPHINE, LEVORPHAN, METHADONE AND PETHIDINE ANALGESIA IN MICE BY "SPECIFIC" AND "NONSPECIFIC" ANTAGONISTS].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1963, Nov-08, Volume: 246

    Topics: Analgesia; Animals; Atropine; Levorphanol; Meperidine; Mephenesin; Meprobamate; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain Management; Peptides; Phenobarbital; Research; Reserpine; Tissue Extracts

1963
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jan-01, Volume: 147

    Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology

1964
ELEVATION OF PLASMA HISTAMINE LEVELS IN THE DOG FOLLOWING ADMINISTRATION OF MUSCLE RELAXANTS, OPIATES AND MACROMOLECULAR POLYMERS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 143

    Topics: Acacia; Analgesics, Opioid; Blood Chemical Analysis; Codeine; Dextrans; Diatrizoate; Dogs; Histamine; Meperidine; Mesylates; Methadone; Morphine; Muscle Relaxants, Central; Niacin; Nicotinic Acids; Pharmacology; Povidone; Research; Starch; Succinylcholine; Tubocurarine

1964
DOUBLE BLIND TRIAL OF DEXTROMORAMIDE, METHADONE AND PETHIDINE IN THE TREATMENT OF SEVERE PAIN.
    Postgraduate medical journal, 1964, Volume: 40

    Topics: Dextromoramide; Double-Blind Method; Humans; Meperidine; Methadone; Pain; Toxicology

1964
ANALGESICS FOR THE RELIEF OF PAIN. I. NARCOTIC ANALGESICS.
    Wisconsin medical journal, 1964, Volume: 63

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pain; Phenazocine; Piperidines

1964
[RE-ANESTHESIA].
    Der Anaesthesist, 1964, Volume: 13

    Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, General; Anesthesiology; Atropa belladonna; Atropine; Barbiturates; Chlorpromazine; Dihydroergotoxine; Ergot Alkaloids; Humans; Meperidine; Methadone; Morphine; Procainamide; Promazine; Promethazine; Reserpine; Scopolamine

1964
EXPERIMENTAL NARCOTIC ADDICTION.
    Scientific American, 1964, Volume: 210

    Topics: Animals; Codeine; Conditioning, Psychological; Equipment and Supplies; Haplorhini; Injections, Intravenous; Meperidine; Methadone; Morphine Dependence; Nalorphine; Opioid-Related Disorders; Rats; Substance-Related Disorders

1964
STATISTICS AS APPLIED TO PHARMACOLOGICAL AND TOXICOLOGICAL SCREENING.
    Progress in medicinal chemistry, 1963, Volume: 19

    Topics: Arsphenamine; Atropine; Biological Assay; Biometry; Cocaine; Digoxin; Epinephrine; Ergonovine; Ergot Alkaloids; Hexamethonium Compounds; Histamine; Insulin; Meperidine; Methadone; Morphine; Pharmacology; Promethazine; Research; Riboflavin; Statistics as Topic; Strophanthins; Toxicology; Tubocurarine

1963
BARBITURATE USE IN NARCOTIC ADDICTS.
    JAMA, 1964, Aug-03, Volume: 189

    Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine Dependence; Narcotics; Opium; Pentobarbital; Seizures; Statistics as Topic; Substance-Related Disorders; Toxicology; Urea

1964
STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS. I. ABSOLUTE CONFIGURATION OF CERTAIN ANALGESIC (-)-N-(2-(PHENALKYLMETHYLAMINO)PROPYL)PROPIONANILIDES.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Meperidine; Methadone; Morphine; Pharmacology; Pharmacy; Research

1964
QUANTITATIVE STUDIES OF THE ANTAGONISM BY NALORPHINE OF SOME OF THE ACTIONS OF MORPHINE-LIKE ANALGESIC DRUGS.
    British journal of pharmacology and chemotherapy, 1964, Volume: 22

    Topics: Analgesics; Animals; Body Temperature; Dextromoramide; Lens, Crystalline; Levorphanol; Meperidine; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pharmacology; Research; Skin

1964
A RAPID SCREENING TEST FOR POTENTIAL ADDICTION LIABILITY OF NEW ANALGESIC AGENTS.
    Toxicology and applied pharmacology, 1964, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior, Addictive; Codeine; Dextropropoxyphene; Heroin; Hydromorphone; Meperidine; Methadone; Mice; Morphine; Phenazocine; Research; Substance-Related Disorders; Toxicology

1964
CONGENITAL NEONATAL NARCOTICS ADDICTION: A NATURAL HISTORY.
    American journal of public health and the nation's health, 1964, Volume: 54

    Topics: Chlorpromazine; Female; Humans; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine Dependence; Mortality; Narcotics; Opioid-Related Disorders; Opium; Phenobarbital; Pregnancy; Psychotherapy; Social Conditions; Substance-Related Disorders

1964
THE ACTION OF MORPHINE-LIKE DRUGS ON IMPULSE TRANSMISSION IN MAMMALIAN NERVE FIBRES.
    British journal of pharmacology and chemotherapy, 1964, Volume: 22

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Cats; Conditioning, Psychological; Hypogastric Plexus; Lagomorpha; Mammals; Meperidine; Methadone; Morphine; Nalorphine; Nerve Fibers; Neural Conduction; Nictitating Membrane; Pharmacology; Rabbits; Research; Sympathetic Nervous System

1964
[CONTROLLABLE APNEA IN ANESTHESIA BY MEANS OF CENTRAL DEPRESSION DUE TO ANALGESICS].
    Gazzetta internazionale di medicina e chirurgia, 1964, Nov-30, Volume: 68

    Topics: Analgesics; Anesthesia; Apnea; Central Nervous System Agents; Depression; Dextromoramide; Humans; Meperidine; Methadone; Morphine; Nalorphine

1964
[ANALGESIA FOLLOWING GYNECOLOGICAL OPERATIONS].
    Die Medizinische Welt, 1965, Feb-06, Volume: 14

    Topics: Analgesia; Drug Therapy; Female; Genital Diseases, Female; Humans; Meperidine; Methadone; Pain; Phenothiazines; Surgical Procedures, Operative

1965
FLUOROMETRIC IDENTIFICATION OF SUB-MICROGRAM AMOUNTS OF MORPHINE AND RELATED COMPOUNDS ON THIN-LAYER CHROMATOGRAPHS.
    Journal of chromatography, 1964, Volume: 16

    Topics: Chemistry, Pharmaceutical; Chromatography; Fluorescence; Fluorometry; Meperidine; Methadone; Morphine; Nalorphine; Research

1964
CARDIOVASCULAR ACTIONS OF NARCOTIC ANALGESICS.
    American heart journal, 1965, Volume: 69

    Topics: Cardiovascular Diseases; Drug Therapy; Humans; Meperidine; Methadone; Morphine; Narcotics; Pharmacology; Toxicology

1965
A METHOD FOR THE THIN-LAYER CHROMATOGRAPHY OF ANALGESIC DRUGS AND RELATED COMPOUNDS IN NON-AQUEOUS SYSTEMS.
    Journal of chromatography, 1965, Volume: 17

    Topics: Ammonia; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Azepines; Chromatography; Chromatography, Thin Layer; Cocaine; Codeine; Dextropropoxyphene; Isonipecotic Acids; Meperidine; Methadone; Morphine; Research

1965
EFFECT OF CENTRAL DEPRESSANT AGENTS ON CEREBRAL GLUCOSE 6-PHOSPHATE DEHYDROGENASE ACTIVITY OF RATS.
    Journal of neurochemistry, 1965, Volume: 12

    Topics: Adrenal Glands; Brain; Chloroform; Erythrocytes; Ethanol; Glucose; Glucosephosphate Dehydrogenase; Kidney; Liver; Meperidine; Methadone; Morphine; NADP; Nalorphine; Pentobarbital; Pharmacology; Phosphates; Rats; Research; Spleen; Sulfhydryl Compounds

1965
[Analgetic effect of morphine, dolsin and mecodin in various ways of application; a pharmacological study].
    Ceskoslovenska farmacie, 1955, Volume: 4, Issue:3

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Meperidine; Methadone; Morphine; Pain; Pain Management

1955
[Action of various pharmacological agents on the exhaustion time and behavior of mice swimming at 20 degrees C. II. Analgesics (morphine, dextromoramide, methadone, pethidine and 3570 CT). Influence of repetition of the test].
    Archives internationales de pharmacodynamie et de therapie, 1962, Feb-01, Volume: 135

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Dextromoramide; Fatigue; Leadership; Meperidine; Methadone; Mice; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed

1962
Variable modulation of opioid brain uptake by P-glycoprotein in mice.
    Biochemical pharmacology, 2004, Jan-15, Volume: 67, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzomorphans; Biological Transport; Brain; Drug Interactions; Fentanyl; Loperamide; Meperidine; Methadone; Mice; Narcotics; Quinidine; Time Factors; Verapamil

2004
Therapeutics and toxicology.
    Annual review of medicine, 1950, Volume: 1

    Topics: Anemia; Anemia, Pernicious; Antacids; Anti-Bacterial Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure; Cortisone; Dibenzylchlorethamine; Dicumarol; Epilepsy; Ergot Alkaloids; Heart Failure; Heparin; Histamine Antagonists; Humans; Hyaluronoglucosaminidase; Hydantoins; Hypersensitivity; Hypertension; Hyperthyroidism; Imidazoles; Iodine; Iodine Isotopes; Kidney; Meperidine; Mephenesin; Methadone; Motion Sickness; Norepinephrine; Organomercury Compounds; Peptic Ulcer; Tetraethylammonium; Therapeutics; Thiouracil; Thrombosis; Veratrum; Vitamin B 12

1950
The action of morphine, pethidine, and amidone upon the intestinal motility of conscious dogs.
    British journal of pharmacology and chemotherapy, 1950, Volume: 5, Issue:4

    Topics: Animals; Consciousness; Dogs; Gastrointestinal Motility; Humans; Intestines; Meperidine; Methadone; Morphine

1950
The effects of morphine methadone and meperidine on some reflex responses of spinal animals to nociceptive stimulation.
    The Journal of pharmacology and experimental therapeutics, 1951, Volume: 101, Issue:2

    Topics: Animals; Meperidine; Methadone; Morphine; Reflex

1951
Studies on a new spasmolytic compound 1,1-diphenyl-3-dimethylaminobutene-1 (A29), related to methadone, and on the combined use of this compound and a potent analgesic, ketobemidone (A21).
    Acta pharmacologica et toxicologica, 1951, Volume: 7, Issue:1

    Topics: Analgesics; Biphenyl Compounds; Humans; Meperidine; Methadone; Parasympatholytics; Piperidines

1951
[Determination of polamidon and dolantin in the urine, and their separation from morphine].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1951, Volume: 212, Issue:5-6

    Topics: Body Fluids; Meperidine; Methadone; Morphine; Rare Diseases; Retinal Degeneration; Retinal Detachment; Urine

1951
[Effect of morphine, dolantin and polamidon on the small intestine of man].
    Klinische Wochenschrift, 1951, Sep-01, Volume: 29, Issue:33-34

    Topics: Intestine, Small; Intestines; Meperidine; Methadone; Morphine

1951
"Opioid creep" is real and may be the cause of "fluid creep".
    Burns : journal of the International Society for Burn Injuries, 2004, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Body Surface Area; Burns; Female; Fentanyl; Fluid Therapy; Humans; Hypnotics and Sedatives; Male; Meperidine; Methadone; Middle Aged; Morphine; Narcotics; Retrospective Studies

2004
A comparison of the antidiuretic effect of demerol and of methadone diuresis in congestive heart failure; a case report.
    The Journal of the Maine Medical Association, 1949, Volume: 40, Issue:10

    Topics: Antidiuretic Agents; Diuresis; Diuretics; Heart; Heart Failure; Humans; Meperidine; Methadone

1949
On pethidine and methadone derivatives.
    Bulletin of the World Health Organization, 1949, Volume: 2, Issue:2

    Topics: Meperidine; Methadone

1949
A comparison of the actions of meperidine, Nu-1196, methadone, morphine, Nu-2206, and metopon upon the intestine and uterus.
    The Journal of pharmacology and experimental therapeutics, 1950, Volume: 99, Issue:3

    Topics: Female; Humans; Intestines; Meperidine; Methadone; Morphinans; Morphine; Uterus

1950
A comparison of certain actions of demerol and methadone.
    California medicine, 1949, Volume: 70, Issue:1

    Topics: Humans; Meperidine; Methadone; Morphine; Narcotics

1949
Inhibition of succinic oxidase system by meperidine, methadon, morphine, and codeine.
    The Journal of pharmacology and experimental therapeutics, 1949, Volume: 95, Issue:2

    Topics: Codeine; Coloring Agents; Meperidine; Methadone; Morphine; Oxidoreductases; Peroxidase; Peroxidases; Succinate Dehydrogenase

1949
OCCURRENCE IN RODENTS OF REVERSIBLE DRUG-INDUCED OPACITIES OF THE LENS.
    The British journal of ophthalmology, 1961, Volume: 45, Issue:6

    Topics: Analgesics, Opioid; Animals; Cataract; Chickens; Guinea Pigs; Humans; Injections, Subcutaneous; Lens Capsule, Crystalline; Lens, Crystalline; Meperidine; Methadone; Mice; Morphine; Pupil; Rats; Recovery of Function

1961
Comparative study of some actions of demerol and methadon.
    Boletin de la Asociacion Medica de Puerto Rico, 1948, Volume: 40, Issue:1

    Topics: Humans; Meperidine; Methadone

1948
Analgesic effects in human subjects of morphine, meperidina and methadon.
    Journal of the American Medical Association, 1948, Jun-12, Volume: 137, Issue:7

    Topics: Analgesics; Humans; Meperidine; Methadone; Morphine; Morphine Derivatives

1948
Acute vascular tolerance to morphine, isonipecaine (demerol) and methadon (amidone) in the dog.
    The Journal of pharmacology and experimental therapeutics, 1948, Volume: 92, Issue:4

    Topics: Animals; Blood Vessels; Dogs; Drug Tolerance; Immune Tolerance; Meperidine; Methadone; Morphine

1948
Some effects of 1-methyl-4-phenyl ethyl isonipecotate (demerol) and 6-dimethylamino-4,4,-diphenyl-3-heptanone (amidone) upon the metabolism of rat brain tissue in vitro.
    The Journal of pharmacology and experimental therapeutics, 1947, Volume: 91, Issue:2

    Topics: Animals; Biphenyl Compounds; Brain; In Vitro Techniques; Ketones; Meperidine; Methadone; Rats

1947
Acute vascular tolerance to morphine, demerol, and 1,1-diphenyl-1-(dimethylamino-isopropyl) butanone-2 (amidone) in the dog.
    Federation proceedings, 1947, Volume: 6, Issue:1

    Topics: Animals; Biphenyl Compounds; Butanones; Dogs; Drug Tolerance; Humans; Meperidine; Methadone; Morphine

1947
Topical methadone and meperidine analgesic synergy in the mouse.
    European journal of pharmacology, 2010, Jul-25, Volume: 638, Issue:1-3

    Topics: Administration, Cutaneous; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Lidocaine; Male; Meperidine; Methadone; Mice; Mice, Inbred Strains; Morphine; Pain Measurement

2010
Determination of stimulants and narcotics as well as their in vitro metabolites by online CE-ESI-MS.
    Electrophoresis, 2011, Volume: 32, Issue:3-4

    Topics: 2-Propanol; Amphetamine; Animals; Codeine; Electrophoresis, Capillary; Ephedrine; Heroin; Hydrogen-Ion Concentration; Male; Meperidine; Methadone; Microsomes, Liver; Narcotics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tetracaine

2011
Is maternal opioid use hazardous to breast-fed infants?
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:1

    Topics: Age Factors; Analgesics, Opioid; Breast Feeding; Buprenorphine; Codeine; Female; Humans; Hydrocodone; Infant; Infant, Newborn; Meperidine; Methadone; Milk, Human; Morphine; Oxycodone

2012
Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine.
    Rapid communications in mass spectrometry : RCM, 2012, Jan-30, Volume: 26, Issue:2

    Topics: Diphenhydramine; Humans; Limit of Detection; Linear Models; Liquid Phase Microextraction; Meperidine; Methadone; Nortriptyline; Pharmaceutical Preparations; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2012
Nano-electromembrane extraction.
    Analytica chimica acta, 2013, Jun-27, Volume: 785

    Topics: Electricity; Electrophoresis, Capillary; Ethers; Haloperidol; Loperamide; Membranes, Artificial; Meperidine; Methadone; Nanotechnology; Nortriptyline; Sodium Chloride; Solutions; Sulfates; Water

2013
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
LC-MS-MS Method for the Analysis of Miscellaneous Drugs in Wastewater During Football Games III.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:8

    Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Residues; Fentanyl; Football; Humans; Illicit Drugs; Limit of Detection; Meperidine; Methadone; Mississippi; Phencyclidine; Pyrrolidines; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater

2016
Declines and regional variation in opioid distribution by U.S. hospitals.
    Pain, 2022, 06-01, Volume: 163, Issue:6

    Topics: Analgesics, Opioid; Buprenorphine; Codeine; Hospitals; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Oxymorphone; United States

2022
Sedation quality of alfaxalone associated with butorphanol, methadone or pethidine in cats injected into the supraspinatus or the quadriceps muscle.
    Journal of feline medicine and surgery, 2022, Volume: 24, Issue:8

    Topics: Anesthesia; Animals; Butorphanol; Cat Diseases; Cats; Hypnotics and Sedatives; Injections, Intramuscular; Meperidine; Methadone; Mydriasis; Pregnanediones; Quadriceps Muscle; Rotator Cuff

2022