Compounds > methadone

methadone and loperamide

methadone has been researched along with loperamide in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's9 (81.82)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dagenais, C; Graff, CL; Pollack, GM1
Amasheh, S; Grobosch, T; Rubelt, MS; Stein, C1
Hansen, SH; Jensen, H; Li, B; Payán, MD; Pedersen-Bjergaard, S; Petersen, NJ1
Gibbs, ME; Ledwitch, KV; Roberts, AG; Wilt, LA1
Livingston, KE; Mahoney, JP; Manglik, A; Sunahara, RK; Traynor, JR1
Krieg, B1
Heller, NM; Maher, DP; Walia, D1
Barnett, BS; Suzuki, J; Ward, HB1
Haigney, MCP; Kao, DP; Kleiman, RB; Klein, M; Krantz, MJ; Rudo, TJ; Stockbridge, N1

Reviews

1 review(s) available for methadone and loperamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for methadone and loperamide

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Variable modulation of opioid brain uptake by P-glycoprotein in mice.
    Biochemical pharmacology, 2004, Jan-15, Volume: 67, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzomorphans; Biological Transport; Brain; Drug Interactions; Fentanyl; Loperamide; Meperidine; Methadone; Mice; Narcotics; Quinidine; Time Factors; Verapamil

2004
Liquid chromatography-tandem mass spectrometry for analysis of intestinal permeability of loperamide in physiological buffer.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Buffers; Caco-2 Cells; Chromatography, Liquid; Humans; Intestines; Ions; Limit of Detection; Loperamide; Methadone; Permeability; Reference Standards; Tandem Mass Spectrometry

2012
Nano-electromembrane extraction.
    Analytica chimica acta, 2013, Jun-27, Volume: 785

    Topics: Electricity; Electrophoresis, Capillary; Ethers; Haloperidol; Loperamide; Membranes, Artificial; Meperidine; Methadone; Nanotechnology; Nortriptyline; Sodium Chloride; Solutions; Sulfates; Water

2013
A Conformationally Gated Model of Methadone and Loperamide Transport by P-Glycoprotein.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:7

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B; Binding Sites; Biological Transport; Hydrolysis; Loperamide; Methadone; Mice; Protein Conformation

2018
Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor.
    eLife, 2018, 06-22, Volume: 7

    Topics: Allosteric Regulation; Allosteric Site; Biosensing Techniques; Biotin; Humans; Interferometry; Ligands; Loperamide; Methadone; Protein Binding; Receptors, Opioid, mu; Sensitivity and Specificity; Single-Domain Antibodies; Small Molecule Libraries; Solutions; Streptavidin; Thiophenes; Urea

2018
    Medizinische Monatsschrift fur Pharmazeuten, 2016, Volume: 39, Issue:11

    Topics: Buprenorphine; Drug Interactions; Germany; Humans; Loperamide; Methadone; Opiate Substitution Treatment; Substance-Related Disorders; Torsades de Pointes

2016
Suppression of Human Natural Killer Cells by Different Classes of Opioids.
    Anesthesia and analgesia, 2019, Volume: 128, Issue:5

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Anesthesia; Buprenorphine; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Fluoresceins; Humans; Immunosuppression Therapy; K562 Cells; Killer Cells, Natural; Loperamide; Methadone; Morphinans; Morphine; Naloxone; Naltrexone; Succinimides; Toll-Like Receptor 4; Tramadol

2019
Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report.
    Substance abuse, 2019, Volume: 40, Issue:2

    Topics: Adult; Antidiarrheals; Antiemetics; Antipruritics; Buprenorphine; Clonidine; Deprescriptions; Drug Substitution; Female; Humans; Loperamide; Methadone; Methocarbamol; Muscle Relaxants, Central; Naltrexone; Narcotic Antagonists; Ondansetron; Opiate Substitution Treatment; Opioid-Related Disorders; Promethazine; Substance Withdrawal Syndrome; Sympatholytics

2019
Ventricular Arrhythmias Associated With Over-the-Counter and Recreational Opioids.
    Journal of the American College of Cardiology, 2023, 06-13, Volume: 81, Issue:23

    Topics: Analgesics, Opioid; Arrhythmias, Cardiac; Buprenorphine; Diphenoxylate; Humans; Loperamide; Methadone; Naltrexone; Nonprescription Drugs

2023