methadone and lidocaine

methadone has been researched along with lidocaine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.21)18.7374
1990's5 (15.15)18.2507
2000's7 (21.21)29.6817
2010's13 (39.39)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gibson, TC1
Brewer, E1
Wood, M1
Coyle, DE; Denson, DD1
Judis, J1
Beckett, AH; Triggs, EJ1
Stolman, A1
Birmingham, PK1
Franke, M; Kingston, HM; Winek, CL1
Barré, J; d'Athis, P; Duché, JC; Hervé, F; Marché, C; Tillement, JP1
Gaillard, Y; Pepin, G1
Pragst, F; Sporkert, F1
VESSMAN, J1
Mosing, M; Olbrich, VH1
Erve, JC1
Kolesnikov, YA; Oksman, G; Pasternak, GW1
Barbera, N; Busardò, FP; Indorato, F; Romano, G1
Lauretti, GR; Mattos, AL; Rizzo, CC; Rodrigues, SW1
Bernardi, CA; Cassu, RN; Diniz, MS; Kanashiro, GP; Nicácio, GM1
Domínguez, JM; Fernández-Sarmiento, JA; Gómez-Villamandos, RJ; Granados, Mdel M; Morgaz, J; Muñoz-Rascón, P; Navarrete, R; Serrano, JM; Serrano-Rodríguez, JM1
de Andrade Bicudo, N; de Assis, KT; DeRossi, R; Hermeto, LC; Jardim, PHA1
Cafrita, IC; Clark, L; Panti, A1
Mitchell, SH; Morris, SC; Wentlandt, M1
Adami, C; Fernandez-Parra, R; Fontaine, C; Zilberstein, L1
Aprea, F; Bhalla, RJ; Cherubini, GB; Corletto, F; De Gennaro, C; Re Bravo, V; Vettorato, E1
Al-Tannak, N; Auckburally, A; Flaherty, D; Gomez, A; Watson, D1

Reviews

6 review(s) available for methadone and lidocaine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The heart in myasthenia gravis.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans; Lidocaine; Meperidine; Methadone; Morphine; Myasthenia Gravis; Myocarditis; Myocardium; Neuromuscular Junction; Phenytoin; Procaine; Quinidine; Vectorcardiography

1975
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors

1986
The absorption, distribution, and excretion of drugs and poisons and their metabolites.
    Progress in chemical toxicology, 1974, Volume: 5

    Topics: Anesthetics; Anesthetics, Local; Animals; Cannabis; Codeine; Gases; Hallucinogens; Halothane; Humans; Hydrocarbons, Fluorinated; Lidocaine; Lysergic Acid Diethylamide; Mepivacaine; Mescaline; Methadone; Methoxyflurane; Narcotics; Pentazocine; Pharmaceutical Preparations; Poisons; Prilocaine; Solvents; Volatilization

1974
Recent advances in acute pain management.
    Current problems in pediatrics, 1995, Volume: 25, Issue:3

    Topics: Acute Disease; Administration, Oral; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Local; Child; Child, Preschool; Drug Combinations; Fentanyl; Humans; Infant; Lidocaine; Lidocaine, Prilocaine Drug Combination; Methadone; Pain; Pain Measurement; Prilocaine; Self Administration

1995
Cyclic metabolites: chemical and biological considerations.
    Current drug metabolism, 2008, Volume: 9, Issue:2

    Topics: Biotransformation; Etidocaine; Humans; Lidocaine; Melatonin; Methadone; Mitoxantrone; Oxazoles; Tocainide; Xenobiotics

2008

Trials

7 trial(s) available for methadone and lidocaine

ArticleYear
A comparison of the analgesic effects of caudal epidural methadone and lidocaine in the horse.
    Veterinary anaesthesia and analgesia, 2003, Volume: 30, Issue:3

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Animals; Ataxia; Cross-Over Studies; Defecation; Double-Blind Method; Female; Horses; Hot Temperature; Injections, Epidural; Lidocaine; Male; Methadone; Pain Measurement; Pilot Projects; Prospective Studies

2003
Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone.
    British journal of cancer, 2013, Feb-05, Volume: 108, Issue:2

    Topics: Adult; Aged; Analgesia, Epidural; Dexamethasone; Drug Administration Routes; Female; Humans; Lidocaine; Male; Methadone; Middle Aged; Neoplasms; Pain; Pain Management

2013
Extradural anesthesia with lidocaine combined with fentanyl or methadone to ovariohisterectomy in dogs.
    Acta cirurgica brasileira, 2013, Volume: 28, Issue:7

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Animals; Blood Pressure; Dogs; Drug Combinations; Female; Fentanyl; Heart Rate; Hysterectomy; Lidocaine; Methadone; Ovariectomy; Reproducibility of Results; Respiratory Rate; Time Factors

2013
Effectiveness of pre-peritoneal continuous wound infusion with lidocaine for pain control following ovariohysterectomy in dogs.
    Veterinary journal (London, England : 1997), 2014, Volume: 202, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Anesthetics, Local; Animals; Dogs; Hysterectomy; Infusions, Parenteral; Injections, Intramuscular; Lidocaine; Methadone; Ovariectomy; Pain Management

2014
Postoperative pain control in cats: clinical trials with pre-emptive lidocaine epidural co-administered with morphine or methadone.
    Journal of feline medicine and surgery, 2016, Volume: 18, Issue:11

    Topics: Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Animals; Cats; Drug Administration Schedule; Drug Therapy, Combination; Female; Hysterectomy; Injections, Epidural; Lidocaine; Methadone; Morphine; Ovariectomy; Pain Measurement; Pain, Postoperative; Treatment Outcome

2016
Effect of intravenous lidocaine on cough response to endotracheal intubation in propofol-anaesthetized dogs.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:4

    Topics: Acepromazine; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Animals; Arterial Pressure; Blood Pressure; Cough; Dog Diseases; Dogs; Dopamine Antagonists; Heart Rate; Hypnotics and Sedatives; Intubation, Intratracheal; Lidocaine; Methadone; Preanesthetic Medication; Propofol; Prospective Studies; Respiratory Rate

2016
Comparison of intratesticular lidocaine, sacrococcygeal epidural lidocaine and intravenous methadone in cats undergoing castration: a prospective, randomized, investigator-blind clinical trial.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:2

    Topics: Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Animals; Cats; Dexmedetomidine; Fentanyl; Lidocaine; Male; Methadone; Orchiectomy; Pain, Postoperative; Pregnanediones; Prospective Studies; Sacrococcygeal Region; Testis

2017

Other Studies

20 other study(ies) available for methadone and lidocaine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A dextromoramide-related fatality.
    Journal of forensic sciences, 1990, Volume: 35, Issue:2

    Topics: Adult; Chromatography, Gas; Dextromoramide; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Humans; Lidocaine; Male; Methadone

1990
Simultaneous measurement of bupivacaine, etidocaine, lidocaine, meperidine, mepivacaine, and methadone.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:1

    Topics: Anesthetics, Local; Bupivacaine; Chromatography, Gas; Etidocaine; Humans; Lidocaine; Meperidine; Mepivacaine; Methadone

1986
Effect of pH on charcoal adsorption of lidocaine, methadone, pilocarpine, and procaine.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:4

    Topics: Adsorption; Charcoal; Hydrogen-Ion Concentration; Lidocaine; Methadone; Pilocarpine; Procaine

1985
Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19

    Topics: Adult; Amines; Amphetamine; Appetite Depressants; Benzphetamine; Biological Transport; Chlorpheniramine; Chlorphentermine; Ephedrine; Fenfluramine; Furans; Humans; Hydrogen-Ion Concentration; Lidocaine; Male; Membranes; Meperidine; Mephentermine; Methadone; Models, Biological; Morpholines; Mouth; Nicotine; Phenethylamines; Phenmetrazine; Phenylpropanolamine

1967
Extraction of selected drugs from serum using microwave irradiation.
    Forensic science international, 1996, Jul-31, Volume: 81, Issue:1

    Topics: Analgesics; Blood Chemical Analysis; Chromatography, Gas; Dextropropoxyphene; Diazepam; Humans; Lidocaine; Methadone; Microwaves; Narcotics; Nordazepam; Retrospective Studies

1996
Binding of disopyramide, methadone, dipyridamole, chlorpromazine, lignocaine and progesterone to the two main genetic variants of human alpha 1-acid glycoprotein: evidence for drug-binding differences between the variants and for the presence of two separ
    Pharmacogenetics, 1996, Volume: 6, Issue:5

    Topics: Binding, Competitive; Carrier Proteins; Chlorpromazine; Dipyridamole; Disopyramide; Genetic Variation; Humans; Lidocaine; Ligands; Methadone; Orosomucoid; Pharmaceutical Preparations; Progesterone

1996
Case report of an unusual use of lidocaine during episodes of self mutilation.
    Journal of forensic sciences, 1998, Volume: 43, Issue:1

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Autopsy; Chromatography, Gas; Cocaine; Dextromoramide; Drug Combinations; Forensic Medicine; Hair; Humans; Lidocaine; Male; Methadone; Self Mutilation; Substance Abuse Detection; Substance-Related Disorders

1998
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
    Forensic science international, 2000, Jan-10, Volume: 107, Issue:1-3

    Topics: Antidepressive Agents, Tricyclic; Cannabinoids; Chlormethiazole; Diphenhydramine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Lidocaine; Methadone; Nicotine; Poisoning; Sensitivity and Specificity; Solvents; Substance Abuse Detection; Tramadol

2000
GAS CHROMATOGRAPHY OF HIGH-BOILING AMINES. II. DETERMINATION OF AMINES IN LOW CONCENTRATION.
    Acta pharmaceutica Suecica, 1964, Volume: 1

    Topics: Amines; Chemistry, Pharmaceutical; Chromatography; Chromatography, Gas; Cocaine; Codeine; Ephedrine; Lidocaine; Methadone; Morphine; Pharmacy; Promazine; Research; Scopolamine

1964
Topical methadone and meperidine analgesic synergy in the mouse.
    European journal of pharmacology, 2010, Jul-25, Volume: 638, Issue:1-3

    Topics: Administration, Cutaneous; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Lidocaine; Male; Meperidine; Methadone; Mice; Mice, Inbred Strains; Morphine; Pain Measurement

2010
The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.
    Forensic science international, 2013, Apr-10, Volume: 227, Issue:1-3

    Topics: Adult; Anesthetics, Local; Antitussive Agents; Bile; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Citalopram; Codeine; Dextromethorphan; Drug Contamination; Drug Overdose; Drug Users; Female; Forensic Pathology; Forensic Toxicology; Gastrointestinal Contents; Humans; Illicit Drugs; Kidney; Lidocaine; Liver; Lung; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Pyrrolidines; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Vitreous Body

2013
Ventricular tachycardia and prolonged QT interval presenting as seizure-like activity.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:5

    Topics: Adult; Alcoholism; Anti-Arrhythmia Agents; Anticonvulsants; Diuretics; Electrocardiography; Emergency Medical Services; Female; Humans; Infusions, Intravenous; Lidocaine; Long QT Syndrome; Magnesium Sulfate; Methadone; Seizures; Tachycardia, Ventricular; Treatment Outcome; Water-Electrolyte Balance

2017
Effect of 5% transdermal lidocaine patches on postoperative analgesia in dogs undergoing hemilaminectomy.
    The Journal of small animal practice, 2019, Volume: 60, Issue:3

    Topics: Analgesia; Animals; Dogs; Lidocaine; Methadone; Pain, Postoperative; Prospective Studies

2019
Stability of dilutions of methadone alone, and in combination with lidocaine and ketamine.
    The Journal of small animal practice, 2022, Volume: 63, Issue:7

    Topics: Animals; Chromatography, High Pressure Liquid; Drug Packaging; Drug Stability; Ketamine; Lidocaine; Methadone; Ringer's Lactate; Saline Solution; Temperature

2022