methadone and levorphanol

methadone has been researched along with levorphanol in 90 studies

Research

Studies (90)

TimeframeStudies, this research(%)All Research%
pre-199071 (78.89)18.7374
1990's5 (5.56)18.2507
2000's10 (11.11)29.6817
2010's3 (3.33)24.3611
2020's1 (1.11)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carroll, FI; Che, T; Huang, XP; Jin, J; Karpiak, J; Kroeze, WK; Lansu, K; Liu, J; McCorvy, JD; Nagase, H; Roth, BL; Shoichet, BK1
Blundell, C; Slater, P1
Herndon, BL; Ringle, DA1
Dewey, WL; Forbes, JE1
Terenius, L4
Cho, TM; Law, PY; Loh, HH; Ostwald, T; Way, EL1
Spoerlein, MT; VanderWende, C1
Chen, RC; Ho, AK; Ho, CC1
Baeder, H; Herndon, BL; Paull, K; Ringle, DA1
Jhamandas, K; Moffat, JA1
Haigler, HJ1
Chen, RC; Ho, AK1
Dahlstrom, J; Medzihradsky, F1
Hron, V; Jhamandas, K; Sutak, M1
Adams, JU; Holtzman, SG; Paronis, CA1
Frank, GB; Kokate, TG1
Foley, KM; Inturrisi, CE; Moulin, DE; Portenoy, RK; Rogers, A1
Foley, KM; Houde, RW; Inturrisi, CE; Moulin, DE; Nip, TJ; Reidenberg, B; Wallenstein, S; Weinberg, DS1
Foley, KM; Portenoy, RK1
Bowman, ER; Brase, DA; Dewey, WL; Kachur, JF; Martin, BR; Rosemond, R; Welch, S1
Gorodetzky, CW1
Eddy, NB; May, EL1
Bastos, ML; Jukofsky, D; Mulé, SJ1
Casella, G; Clouet, DH; Mule, SJ1
Brister, CC; Davis, WM2
Prianishnikova, NT; Raevskii, KS2
Gavitt, J; Karmin, M; Smith, AA1
Ettinger, MJ; Gero, A2
Röthig, J1
Fujimoto, JM; Wang, RI1
Herz, A; Hess, R; Teschemacher, H; von Cube, B1
Gero, A1
Goldstein, A1
Hayashi, G; Maruyama, Y; Smits, SE; Takemori, AE1
Collier, HO; Roy, AC1
Stesin, AJ; Takemori, AE; Tulunay, FC1
Takemori, AE; Tulunay, FC1
Edelman, I; Hiller, JM; Simon, EJ1
Crofford, M; Hui, F; Smith, AA1
Simon, EJ1
Chau-Wong, M; Moyyen, S; Seeman, P1
Sinclair, JG1
Hui, F; Smith, AA1
Carmichael, FJ; Israel, Y1
Granat, FR; Saelens, JK1
Horng, JS; Wong, DT1
Burke, DH; Mann, DE1
Dundee, JW; Jones, PO1
Mueller, GC; Noteboom, WD1
Kreppel, E1
Dundee, JW; Loan, WB; Morrison, JD1
Smits, SE; Takemori, AE2
Goldstein, A; Richter, JA1
Rethy, CR; Smith, CB; Villarreal, JE1
Akera, T; Brody, TM1
Fujimoto, FM; Inturrisi, CE1
Benzi, G; Berté, F; Crema, A; Frigo, GM1
Burks, TF; Long, JP1
Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE1
Huidobro, F; Huidobro-Toro, JP1
Romankiewicz, JA1
Juskevich, JC; Lovenberg, W; O'Callaghan, JP1
Blake, AD; Bot, G; Freeman, JC; Reisine, T1
Jyske, P; Porras, SP; Riekkola, ML; Valkó, IE1
Jussila, M; Porras, SP; Riekkola, ML; Sinervo, K1
Derby, S; Fischberg, D; Kornick, C; Manfredi, PL; Moryl, N; Payne, R; Santiago-Palma, J1
Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO2
Foley, KM1
SLEETH, CK; SLOMKA, MB1
JACOBSEN, FG; SCHAFII-LASCHTENESCHAI, AH; ZETLER, G1
COX, BM; WEINSTOCK, M1
DUNDEE, JW1
GYANG, EA; KOSTERLITZ, HW; LEES, GM1
Gibert-Rahola, J; Mico, JA; Rojas-Corrales, MO1
Ballas, SK1
McNulty, JP2
Prommer, EE1
Fudin, J; Pham, TC; Raffa, RB1
Haider, A; Reddy, A1

Reviews

8 review(s) available for methadone and levorphanol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Possible involvement of cerebroside sulfate in opiate receptor binding.
    Federation proceedings, 1978, Volume: 37, Issue:2

    Topics: Animals; Azure Stains; Binding Sites; Brain; Cerebrosides; Humans; Levorphanol; Methadone; Mice; Naloxone; Receptors, Neurotransmitter; Receptors, Opioid; Sulfanilic Acids

1978
[Analgesics. 32].
    Pharmazeutische Praxis, 1969, Volume: 5

    Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine

1969
Interactions of narcotic antagonists with receptor sites.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Acetylcholine; Animals; Atropine; Binding Sites; Brain; Chromatography; Drug Tolerance; Electric Stimulation; Haplorhini; Humans; Kinetics; Levorphanol; Methadone; Mice; Molecular Conformation; Morphine; Naloxone; Narcotic Antagonists; Rats; Receptors, Drug; Structure-Activity Relationship; Substance Withdrawal Syndrome; Time Factors

1973
Hypothesis: Inhibition of E prostaglandin-sensitive adenyl cyclase as the mechanism of morphine analgesia.
    Prostaglandins, 1974, Sep-10, Volume: 7, Issue:5

    Topics: Adenylyl Cyclases; Animals; Aspirin; Brain; Cyclic AMP; Depression, Chemical; Fluorides; Guinea Pigs; Heroin; In Vitro Techniques; Levorphanol; Meperidine; Methadone; Mice; Morphinans; Morphine; Naloxone; Prostaglandin Antagonists; Prostaglandins; Rabbits; Rats; Receptors, Drug; Sodium; Stimulation, Chemical

1974
In search of the opiate receptor.
    The American journal of the medical sciences, 1973, Volume: 266, Issue:3

    Topics: Animals; Binding Sites; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, Affinity; Cyclopropanes; Indicators and Reagents; Intestines; Levorphanol; Methadone; Morphinans; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentanols; Rats; Receptors, Drug; Tritium

1973
Is levorphanol a better option than methadone?
    Pain medicine (Malden, Mass.), 2015, Volume: 16, Issue:9

    Topics: Analgesics, Opioid; Humans; Levorphanol; Methadone; Pain Management

2015
Levorphanol versus methadone use: safety considerations.
    Annals of palliative medicine, 2020, Volume: 9, Issue:2

    Topics: Analgesics, Opioid; Central Nervous System; Chronic Pain; Dose-Response Relationship, Drug; Humans; Levorphanol; Methadone; Opioid-Related Disorders; Therapeutic Equivalency

2020

Trials

3 trial(s) available for methadone and levorphanol

ArticleYear
Studies on the relationship between 5-hydroxytryptamine turnover in brain and tolerance and physical dependence in mice.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 178, Issue:1

    Topics: Animals; Aspirin; Brain; Cyclazocine; Drug Tolerance; Fenclonine; Humans; Levorphanol; Male; Methadone; Mice; Morphinans; Morphine; Morphine Dependence; Nalorphine; Pargyline; Pentazocine; Phenylalanine; Physostigmine; Placebos; Serotonin; Substance Withdrawal Syndrome

1971
The prevention of analgesic-induced nausea and vomiting by cyclizine.
    The British journal of clinical practice, 1968, Volume: 22, Issue:9

    Topics: Analgesia; Clinical Trials as Topic; Codeine; Cyclizine; Female; Humans; Levorphanol; Male; Meperidine; Methadone; Nausea; Placebos; Vomiting

1968
Pitfalls of opioid rotation: substituting another opioid for methadone in patients with cancer pain.
    Pain, 2002, Volume: 96, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Hydromorphone; Levorphanol; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Patient Satisfaction; Prospective Studies

2002

Other Studies

79 other study(ies) available for methadone and levorphanol

ArticleYear
In silico design of novel probes for the atypical opioid receptor MRGPRX2.
    Nature chemical biology, 2017, Volume: 13, Issue:5

    Topics: Calcium; Cell Degranulation; Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mast Cells; Molecular Docking Simulation; Molecular Probes; Molecular Structure; Nerve Tissue Proteins; Pyrazoles; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Structure-Activity Relationship

2017
The effect of 6-hydroxydopamine on the antinociceptive action of analgesics in mice.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:5

    Topics: Analgesics, Opioid; Animals; Drug Interactions; Female; Hydroxydopamines; Injections, Intraventricular; Levorphanol; Meperidine; Methadone; Mice; Morphine; Pentazocine; Reaction Time; Time Factors

1977
Immunologic effects of morphine administration in rabbits.
    Journal of immunology (Baltimore, Md. : 1950), 1975, Volume: 115, Issue:3

    Topics: Animals; Antibody Formation; Binding, Competitive; Carbon Radioisotopes; Carrier Proteins; Chemical Fractionation; Codeine; Cyclophosphamide; Drug Implants; Electrophoresis, Polyacrylamide Gel; Female; gamma-Globulins; Hemagglutination Tests; Hemocyanins; Heroin; Immunodiffusion; Levorphanol; Methadone; Morphine; Naloxone; Rabbits; Skin Tests

1975
The effects of narcotic analgesics and narcotic antagonists on ganglionic transmission in the rat.
    Life sciences, 1976, Aug-01, Volume: 19, Issue:3

    Topics: Animals; Ganglia, Autonomic; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Stereoisomerism; Synaptic Transmission

1976
Opioid peptides and opiates differ in receptor selectivity.
    Psychoneuroendocrinology, 1977, Volume: 2, Issue:1

    Topics: Animals; Brain; Dextrorphan; Endorphins; Enkephalins; Isomerism; Levorphanol; Methadone; Morphine; Naloxone; Naltrexone; Rats; Receptors, Opioid

1977
Effect of narcotics on monoamine oxidase activity of mouse brain.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 24, Issue:1

    Topics: Animals; Brain; Kinetics; Levorphanol; Male; Methadone; Mice; Monoamine Oxidase; Morphine; Narcotics

1979
Interaction toxicity between ethanol and narcotics in mice with reference to alpha-1-acetylmethadol (LAAM).
    Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:2

    Topics: Animals; Brain; Dextrorphan; Drug Interactions; Ethanol; Lethal Dose 50; Levorphanol; Male; Methadone; Methadyl Acetate; Mice; Morphine; Narcotics

1978
Comparison of immunogenicity of opiates bound to protein at different sites on the molecule: N-carboxy morphine-BSA.
    Pharmacological research communications, 1976, Volume: 8, Issue:3

    Topics: Animals; Antibody Specificity; Binding Sites; Carrier Proteins; Codeine; Haptens; Heroin; Immune Sera; Immunologic Techniques; Levorphanol; Methadone; Morphine; Morphine Derivatives; Naloxone; Protein Binding; Rabbits; Rats; Serum Albumin, Bovine; Structure-Activity Relationship

1976
Effects of acute and chronic methadone treatment of the uptake of 3H-5-hydroxytryptamine in rat hypothalamus slices.
    European journal of pharmacology, 1976, Volume: 36, Issue:2

    Topics: Animals; Dextrorphan; Female; Heroin; Humans; Hypothalamus; In Vitro Techniques; Levorphanol; Methadone; Morphine; Naloxone; Rats; Serotonin; Substance Withdrawal Syndrome; Time Factors

1976
Morphine: ability to block neuronal activity evoked by a nociceptive stimulus.
    Life sciences, 1976, Sep-15, Volume: 19, Issue:6

    Topics: Action Potentials; Animals; Brain Stem; Chlorpromazine; Levorphanol; Male; Methadone; Morphine; Naloxone; Oxymorphone; Pain; Pentobarbital; Rats; Reticular Formation

1976
Interactions of narcotics, narcotic antagonists, and ethanol during acute, chronic, and withdrawal states.
    Annals of the New York Academy of Sciences, 1976, Volume: 281

    Topics: Alcohol Drinking; Animals; Animals, Newborn; Dextrorphan; Drug Interactions; Ethanol; Humans; Levorphanol; Male; Methadone; Methadyl Acetate; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1976
Concurrent determination of narcotic drugs in plasm by gas-liquid chromatography.
    Pharmacological research communications, 1975, Volume: 07, Issue:1

    Topics: Chromatography, Gas; Cocaine; Codeine; Cyclazocine; Humans; Levallorphan; Levorphanol; Methadone; Methods; Nalorphine; Naloxone; Narcotics; Pentazocine

1975
Comparative effects of opiate agonists methadone, levorphanol, and their isomers on the release of cortical ACh in vivo and in vitro.
    Canadian journal of physiology and pharmacology, 1975, Volume: 53, Issue:4

    Topics: Acetylcholine; Adrenal Cortex; Adrenal Glands; Animals; Dextrorphan; In Vitro Techniques; Levorphanol; Methadone; Naloxone; Rats; Stereoisomerism; Time Factors

1975
Assessment of relative intrinsic activity of mu-opioid analgesics in vivo by using beta-funaltrexamine.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Fentanyl; Levorphanol; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Time Factors

1990
Blockade of high K+ contractures and Ca(+)+-dependent slow action potentials in frog skeletal muscle by opioid drugs.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: Action Potentials; Animals; Calcium; Dextrorphan; Endorphins; In Vitro Techniques; Levorphanol; Methadone; Morphine; Muscle Contraction; Muscles; Narcotics; Potassium; Rana pipiens

1990
I.v. infusion of opioids for cancer pain: clinical review and guidelines for use.
    Cancer treatment reports, 1986, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Administration Schedule; Drug Evaluation; Humans; Hydromorphone; Infant; Infusions, Parenteral; Levorphanol; Methadone; Middle Aged; Morphine; Narcotics; Neoplasms; Oxymorphone; Pain, Intractable; Palliative Care; Retrospective Studies

1986
Sublingual absorption of selected opioid analgesics.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3

    Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Analysis of Variance; Biological Availability; Buprenorphine; Fentanyl; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Mouth; Naloxone; Oxycodone; Time Factors

1988
Chronic use of opioid analgesics in non-malignant pain: report of 38 cases.
    Pain, 1986, Volume: 25, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Female; Humans; Levorphanol; Male; Methadone; Middle Aged; Opioid-Related Disorders; Oxycodone; Pain, Intractable; Personality Assessment; Personality Inventory; Retrospective Studies; Risk; Time Factors

1986
Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits.
    Life sciences, 1985, Dec-30, Volume: 37, Issue:26

    Topics: Animals; Biological Assay; Dextrorphan; Diazepam; Dose-Response Relationship, Drug; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Levorphanol; Male; Meperidine; Methadone; Nociceptors; Pentazocine; Pentobarbital; Proadifen; Rabbits; Time Factors

1985
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
The search for a better analgesic.
    Science (New York, N.Y.), 1973, Aug-03, Volume: 181, Issue:4098

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Heroin; Humans; Hydromorphone; Levorphanol; Meperidine; Methadone; Morphinans; Morphine Dependence; Structure-Activity Relationship

1973
Stereospecific uptake of narcotic analgesics by a subcellular fraction of the guinea-pig ileum. A preliminary communication.
    Upsala journal of medical sciences, 1973, Volume: 78, Issue:3

    Topics: Analgesics; Animals; Codeine; Dextromoramide; Female; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Intestinal Absorption; Levorphanol; Male; Methadone; Morphine; Muscle, Smooth; Nalorphine; Naloxone; Narcotics; Subcellular Fractions; Tritium

1973
Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amphetamine; Apomorphine; Barbiturates; Chromatography, Thin Layer; Cocaine; Codeine; Cross Reactions; Cyclazocine; Dextromethorphan; Dextropropoxyphene; Evaluation Studies as Topic; Hemagglutination Inhibition Tests; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Radioimmunoassay; Spectrometry, Fluorescence; Substance-Related Disorders; Time Factors; Tritium

1974
Contribution of 'receptor' affinity to analgesic potency.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: 1-Propanol; Analgesics; Animals; Binding, Competitive; Brain; Cyclopropanes; Fentanyl; Guinea Pigs; Hydromorphone; In Vitro Techniques; Injections, Intravenous; Levorphanol; Meperidine; Methadone; Morphinans; Morphine; Pentanols; Receptors, Drug

1974
Localization of narcotic analgesics in synaptic membranes of rat brain.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:1

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Brain; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Thin Layer; Hot Temperature; Levorphanol; Lipids; Male; Methadone; Microscopy, Electron; Microsomes; Mitochondria; Morphinans; Morphine Derivatives; Naloxone; Pentanols; Rats; Staining and Labeling; Stereoisomerism; Subcellular Fractions; Synaptic Membranes; Tritium

1974
Antagonism of acute lethality of narcotic analgesics in aggregated and isolated mice by the central cholinomimetic action of pilocarpine.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 210, Issue:2

    Topics: Analgesics, Opioid; Animals; Atropine; Atropine Derivatives; Crowding; Depression, Chemical; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Motor Activity; Parasympathomimetics; Pentazocine; Pilocarpine; Social Isolation; Stimulation, Chemical; Time Factors

1974
[Ionization constants of several narcotic analgesics and their pain relieving activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:3

    Topics: Analgesics, Opioid; Benzilates; Chemical Phenomena; Chemistry, Physical; Codeine; Dextromoramide; Dimethylamines; Kinetics; Levorphanol; Meperidine; Methadone; Morphine; Muscle Relaxants, Central; Phenylacetates; Structure-Activity Relationship

1973
Tolerance to the lenticular effects of opiates.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:1

    Topics: Animals; Dactinomycin; Drug Tolerance; Epinephrine; Female; Lens, Crystalline; Levorphanol; Methadone; Mice; Morphine; Puromycin; Reserpine

1967
Interactions of narcotics and their antagonists with human serum esterase. II: nature of the antagonism.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 164, Issue:1

    Topics: Drug Antagonism; Enzymes; Esterases; Humans; Hydromorphone; Levorphanol; Methadone; Models, Theoretical; Morphine; Nalorphine; Narcotic Antagonists; Procaine; Spectrophotometry

1966
Interactions of narcotics and their antagonists with human serum esterase. I: sites of action and nature of the inhibitory effect.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 164, Issue:1

    Topics: Drug Antagonism; Drug Synergism; Enzymes; Esterases; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Procaine; Spectrophotometry

1966
A method of identifying narcotic analgesics in human urine after therapeutic doses.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Alkaloids; Analgesics; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Humans; Hydromorphone; Ion Exchange; Levorphanol; Meperidine; Methadone; Methods; Morphine; Narcotics; Pentazocine

1970
[Permeation of active morphine-like substances at their sites of antinociceptive action in the brain as a function of their lipid-solubility following intravenous and intraventricular application].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 265, Issue:5

    Topics: Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Dental Pulp Test; Fentanyl; Hydromorphone; Ketones; Kinetics; Levorphanol; Lipids; Methadone; Morphinans; Morphine; Piperidines; Rabbits; Solubility; Tritium

1970
Application of enzyme kinetics to a problem in pharmacology: receptor affinities and efficacies in the action of morphine and related drugs on human serum esterase.
    Enzymologia, 1970, May-31, Volume: 38, Issue:5

    Topics: Esterases; Hydromorphone; Kinetics; Levorphanol; Mathematics; Metabolism; Methadone; Morphine; Nalorphine

1970
A single-dose suppression test in morphine-dependent mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:4

    Topics: Aminopyrine; Analgesics; Animals; Behavior, Animal; Humans; Isonipecotic Acids; Levorphanol; Male; Methadone; Mice; Morphinans; Morphine; Morphine Dependence; Motor Activity; Nalorphine; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome

1974
The increased efficacy of narcotic antagonists induced by various narcotic analgesics.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Analgesics; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Drug Synergism; Levorphanol; Male; Methadone; Mice; Morphinans; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Reaction Time; Time Factors

1974
Stereospecific binding of the potent narcotic analgesic (3H) Etorphine to rat-brain homogenate.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:7

    Topics: Acetamides; Analgesics; Animals; Azides; Binding Sites; Binding, Competitive; Brain; Ethylmaleimide; Fluorides; In Vitro Techniques; Levorphanol; Male; Mercuribenzoates; Methadone; Morphinans; Morphine; Nalorphine; Naloxone; Pentanols; Phospholipases; Pronase; Prostaglandins; Rats; Receptors, Drug; Tritium; Trypsin

1973
Trophic functions of the neuron. VI. Other trophic systems. Inhibition of growth by methadone and other cholinolytic drugs.
    Annals of the New York Academy of Sciences, 1974, Mar-22, Volume: 228, Issue:0

    Topics: Ambystoma; Animals; Animals, Newborn; Cell Differentiation; Choline; Depression, Chemical; Female; Growth; Hemicholinium 3; Larva; Levallorphan; Levorphanol; Male; Methadone; Mice; Mice, Inbred Strains; Naloxone; Parasympatholytics; Regeneration; Taste Buds

1974
Adsorption and conduction-block of opiate narcotics on nerve membranes: identical effects of levo- and dextro-forms.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:12

    Topics: Animals; Brain; Carbon Isotopes; Cerebellum; Cerebral Cortex; Guinea Pigs; Hypothalamus; In Vitro Techniques; Isomerism; Levorphanol; Medulla Oblongata; Membranes; Methadone; Morphinans; Neural Conduction; Neurons; Synaptosomes; Thalamus; Tritium

1972
Ethoheptazine-monoamine oxidase inhibitor interaction in rabbits.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:9

    Topics: Alphaprodine; Amines; Analgesics; Animals; Azepines; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Interactions; Female; Fever; Isonipecotic Acids; Levallorphan; Levorphanol; Male; Methadone; Monoamine Oxidase Inhibitors; Nalorphine; Rabbits; Time Factors

1972
Inhibition of neurotrophic activity in salamanders treated with opioids.
    Experimental neurology, 1973, Volume: 39, Issue:1

    Topics: Animals; Hindlimb; Levallorphan; Levorphanol; Methadone; Mitosis; Naloxone; Nerve Regeneration; Taste Buds; Urodela

1973
Acute effects of narcotic analgesics on behavioral arousal in the rat.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:6

    Topics: Analgesics; Animals; Arousal; Dose-Response Relationship, Drug; Levorphanol; Locomotion; Male; Meperidine; Methadone; Methyltyrosines; Morphine; Narcotics; Pentazocine; Rats; Time Factors

1973
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2

    Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium

1973
Effect of stimulus intensity on the potency of some analgetic agents.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:1

    Topics: Analgesics; Animals; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Levorphanol; Male; Meperidine; Methadone; Mice; Mice, Inbred Strains; Naloxone; Pentazocine; Physical Stimulation; Reaction Time; Seizures; Time Factors; Tremor

1973
Stereospecific interaction of opiate narcotics in binding of 3H-dihydromorphine to membranes of rat brain.
    Life sciences, 1973, Dec-01, Volume: 13, Issue:11

    Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Corpus Striatum; Dextromethorphan; Kinetics; Levorphanol; Male; Methadone; Morphine; Naloxone; Protein Binding; Rats; Receptors, Drug; Synaptosomes; Tritium

1973
[Ionization constants of several narcotic analgesics and their pain relieving action].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:1

    Topics: Analgesics; Codeine; Dextromoramide; Dimethylamines; Diphenylacetic Acids; Ethers, Cyclic; Hydrogen-Ion Concentration; Ions; Kinetics; Levorphanol; Mathematics; Meperidine; Methadone; Morphinans; Morphine; Narcotics; Piperidines

1973
Characteristics of the "receptor" for narcotic analgesics in synaptic plasma membrane fraction from rat brain.
    Acta pharmacologica et toxicologica, 1973, Volume: 33, Issue:5

    Topics: Acetylcholine; Animals; Binding, Competitive; Brain Stem; Cerebral Cortex; Chloromercuribenzoates; Codeine; Dextromethorphan; Ethylmaleimide; Female; Heroin; In Vitro Techniques; Levorphanol; Methadone; Morphinans; Morphine; Nalorphine; Naloxone; Physostigmine; Rats; Receptors, Drug; Structure-Activity Relationship; Subcellular Fractions; Synaptic Membranes; Tritium

1973
Thiazine dye antagonism of opioid lethality in mice.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3

    Topics: Animals; Codeine; Dextropropoxyphene; Drug Synergism; Hexobarbital; Lethal Dose 50; Levorphanol; Male; Meperidine; Methadone; Methylene Blue; Mice; Morphinans; Morphine; Sleep; Thiazines; Time Factors; Tolonium Chloride

1974
Inhibition of cell growth and the synthesis of ribonucleic acid and protein in HeLa cells by morphinans and related compounds.
    Molecular pharmacology, 1969, Volume: 5, Issue:1

    Topics: Amino Acids; Carbon Isotopes; Codeine; Culture Techniques; HeLa Cells; Leucine; Levallorphan; Levorphanol; Methadone; Morphinans; Phenazocine; Protein Biosynthesis; Ribosomes; RNA; Thebaine; Time Factors

1969
[Principles and risks of drug treatment of pain].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans; Imipramine; Levallorphan; Levorphanol; Methadone; Morphine; Pain; Phenacetin; Phenylbutazone; Pyrazoles; Salicylamides; Salicylates; Sulfonic Acids

1969
Studies of drugs given before anaesthesia. XIX. The opiates.
    British journal of anaesthesia, 1970, Volume: 42, Issue:1

    Topics: Analgesics; Diazepam; Female; Fentanyl; Heroin; Humans; Levorphanol; Male; Meperidine; Methadone; Morphine; Papaverine; Phenazocine; Preanesthetic Medication; Vomiting

1970
Quantitative studies on the antagonism by naloxone of some narcotic and narcotic-antagonist analgesics.
    British journal of pharmacology, 1970, Volume: 39, Issue:3

    Topics: Animals; Bridged-Ring Compounds; Cyclazocine; Furans; Ketones; Levorphanol; Male; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenanthrenes; Quinones; Receptors, Drug; Spasm

1970
Studies on the receptors involved in the action of the various agents in the phenylbenzoquinone analgesic assay in mice.
    British journal of pharmacology, 1970, Volume: 39, Issue:3

    Topics: Analgesics; Animals; Aspirin; Atropine; Cyclazocine; Drug Tolerance; Levorphanol; Male; Methadone; Mice; Morphine; Nalorphine; Pentazocine; Physostigmine; Quinones; Receptors, Drug; Spasm

1970
The effects of morphine-like compounds on the light responses of the brine shrimp Artemia salina.
    Psychopharmacologia, 1970, Volume: 17, Issue:4

    Topics: Animals; Decapoda; Levorphanol; Light; Methadone; Methods; Morphinans; Morphine; Nalorphine; Pentobarbital; Time Factors

1970
Effects of narcotic analgesics upon the locomotor activity and brain catecholamine content of the mouse.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Catecholamines; Dextroamphetamine; Drug Tolerance; Levorphanol; Locomotion; Male; Methadone; Mice; Morphinans; Morphine; Motor Activity; Narcotics; Thebaine

1971
The addiction cycle to narcotics in the rat and its relation to catecholamines.
    Biochemical pharmacology, 1968, Volume: 17, Issue:5

    Topics: Adrenal Glands; Animals; Body Weight; Brain; Drug Tolerance; Epinephrine; Female; Growth; Humans; Levorphanol; Methadone; Monoamine Oxidase Inhibitors; Morphine; Morphine Dependence; Norepinephrine; Organ Size; Rats; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders; Thebaine; Time Factors

1968
The antidiuretic effect of narcotic analgesics in the mouse.
    Toxicology and applied pharmacology, 1968, Volume: 13, Issue:2

    Topics: Animals; Biological Assay; Diuresis; Drug Antagonism; Fentanyl; Levorphanol; Methadone; Mice; Morphine; Nalorphine; Water

1968
The responses of the terminal bile duct to morphine and morphine-like drugs.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 149, Issue:3

    Topics: Ampulla of Vater; Animals; Bile Ducts; Cats; Cattle; Dextromoramide; Dogs; In Vitro Techniques; Levorphanol; Meperidine; Methadone; Morphine; Tachyphylaxis

1965
Release of intestinal 5-hydroxytryptamine by morphine and related agents.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Calcium; Cocaine; Dogs; Female; Guinea Pigs; Ileum; Injections, Intravenous; Intestinal Mucosa; Intestines; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Nicotine; Rats; Reserpine; Serotonin; Tachyphylaxis; Uterus

1967
Opiates and thermoregulation in mice. I. Agonists.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2

    Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone

1980
Central effects of morphine, levorphanol, (-)-methadone and the opioid-like peptides beta-endorphin and D-alanine2- methionine enkephalinamide on urine volume outflow and electrolytes.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3

    Topics: Animals; beta-Endorphin; Brain; Diuresis; Electrolytes; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Levorphanol; Male; Methadone; Morphine; Naloxone; Narcotics; Rats; Vasopressins

1981
Pharmacology update: strong analgesics - Part I.
    The Journal of practical nursing, 1980, Volume: 30, Issue:3

    Topics: Levorphanol; Methadone; Morphine Derivatives

1980
The effects of morphine on calcium-regulated phosphorylation of synaptosomal cytosolic proteins from rat striatum.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:3

    Topics: Animals; Calcium; Corpus Striatum; Cytosol; In Vitro Techniques; Levorphanol; Male; Methadone; Morphine; Naloxone; Nerve Tissue Proteins; Phosphorylation; Rats; Stereoisomerism; Synaptosomes

1982
Differential opioid agonist regulation of the mouse mu opioid receptor.
    The Journal of biological chemistry, 1997, Jan-10, Volume: 272, Issue:2

    Topics: Adenylate Cyclase Toxin; Analgesics; Animals; Buprenorphine; Colforsin; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Levorphanol; Methadone; Mice; Morphine; Pertussis Toxin; Receptors, Opioid, mu; Virulence Factors, Bordetella

1997
Drugs for pain.
    The Medical letter on drugs and therapeutics, 1998, Aug-14, Volume: 40, Issue:1033

    Topics: Acetaminophen; Administration, Oral; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Aspirin; Constipation; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Tolerance; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Ketorolac; Levorphanol; Meperidine; Methadone; Morphine; Narcotic Antagonists; Narcotics; Pain; Tolmetin; Tramadol

1998
Effect of electrolyte and solvent composition on capillary electrophoretic separation of some pharmaceuticals in non-aqueous media.
    Journal of biochemical and biophysical methods, 1999, Jan-29, Volume: 38, Issue:2

    Topics: Acetates; Acetonitriles; Ammonium Chloride; Bromides; Dextromoramide; Dose-Response Relationship, Drug; Electrolytes; Electrophoresis, Capillary; Ephedrine; Hydrogen-Ion Concentration; Levorphanol; Lithium Compounds; Methadone; Methanol; Morphine; Potassium Acetate; Quaternary Ammonium Compounds; Sodium Acetate; Time Factors; Viscosity

1999
Modified liquid junction interface for nonaqueous capillary electrophoresis-mass spectrometry.
    Electrophoresis, 2000, Volume: 21, Issue:15

    Topics: Codeine; Electrophoresis, Capillary; Equipment Design; Indicators and Reagents; Levorphanol; Methadone; Morphine; Pentazocine; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2000
Antidepressant-like effects of tramadol and other central analgesics with activity on monoamines reuptake, in helpless rats.
    Life sciences, 2002, Nov-29, Volume: 72, Issue:2

    Topics: Affect; Analgesics, Opioid; Animals; Antidepressive Agents; Electroshock; Escape Reaction; Helplessness, Learned; Levorphanol; Male; Methadone; Motor Activity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Swimming; Tramadol

2002
Opioids and chronic neuropathic pain.
    The New England journal of medicine, 2003, Mar-27, Volume: 348, Issue:13

    Topics: Analgesics, Opioid; Chronic Disease; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Levorphanol; Methadone; Neuralgia

2003
Analgetic activity of optical isomers of 3-hydroxy-N-methylmorphinan and 6-dimethylamino-4,4-diphenyl-3-heptanone.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1953, Volume: 84, Issue:3

    Topics: Biphenyl Compounds; Ketones; Levorphanol; Methadone; Morphine Derivatives

1953
[THE INHIBITION OF MORPHINE, LEVORPHAN, METHADONE AND PETHIDINE ANALGESIA IN MICE BY "SPECIFIC" AND "NONSPECIFIC" ANTAGONISTS].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1963, Nov-08, Volume: 246

    Topics: Analgesia; Animals; Atropine; Levorphanol; Meperidine; Mephenesin; Meprobamate; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain Management; Peptides; Phenobarbital; Research; Reserpine; Tissue Extracts

1963
QUANTITATIVE STUDIES OF THE ANTAGONISM BY NALORPHINE OF SOME OF THE ACTIONS OF MORPHINE-LIKE ANALGESIC DRUGS.
    British journal of pharmacology and chemotherapy, 1964, Volume: 22

    Topics: Analgesics; Animals; Body Temperature; Dextromoramide; Lens, Crystalline; Levorphanol; Meperidine; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pharmacology; Research; Skin

1964
A CLINICAL TRIAL OF A MIXTURE OF LEVORPHANOL AND LEVALLORPHAN AS AN ORAL ANALEGESIC.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Drug Therapy; Humans; Levallorphan; Levorphanol; Methadone; Neoplasms; Osteoarthritis; Pain; Substance Withdrawal Syndrome; Toxicology

1964
THE INHIBITION OF AUTONOMIC NEURO-EFFECTOR TRANSMISSION BY MORPHINE-LIKE DRUGS AND ITS USE AS A SCREENING TEST FOR NARCOTIC ANALGESIC DRUGS .
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1964, May-25, Volume: 248

    Topics: Alkaloids; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Autonomic Agents; Cats; Guinea Pigs; Levallorphan; Levorphanol; Methadone; Morphine; Narcotics; Neuromuscular Junction; Nictitating Membrane; Opium; Pharmacology; Phenothiazines; Research

1964
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols; Desipramine; Fluvoxamine; Levorphanol; Male; Methadone; Mice; Morphine; Narcotics; Reserpine; Stereoisomerism; Time Factors; Tramadol; Venlafaxine Hydrochloride

2004
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior.
    Psychopharmacology, 2007, Volume: 190, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Indophenol; Levorphanol; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Stereotyped Behavior; Tics; Tourette Syndrome; Tramadol; Triazoles

2007
Does purity of supplements count?
    The American journal of medicine, 2007, Volume: 120, Issue:1

    Topics: Ascorbic Acid; Drug Contamination; Humans; Levorphanol; Methadone; Phytotherapy; Plant Extracts; Plant Preparations; Quality Control; Randomized Controlled Trials as Topic; Vitamin E

2007
Can levorphanol be used like methadone for intractable refractory pain?
    Journal of palliative medicine, 2007, Volume: 10, Issue:2

    Topics: Analgesics, Opioid; Chronic Disease; Hospice Care; Humans; Levorphanol; Louisiana; Methadone; Pain Measurement; Pain, Intractable; Palliative Care; Treatment Failure; Treatment Outcome

2007
Levorphanol revisited.
    Journal of palliative medicine, 2007, Volume: 10, Issue:6

    Topics: Analgesics, Opioid; Levorphanol; Methadone; Morphine

2007
Chronic pain: levorphanol, methadone, and the N-methyl-D-aspartate receptor.
    Journal of palliative medicine, 2009, Volume: 12, Issue:9

    Topics: Analgesics, Opioid; Chronic Disease; Hospice Care; Humans; Levorphanol; Methadone; N-Methylaspartate; Narcotics; Pain; Palliative Care; Receptors, N-Methyl-D-Aspartate

2009