methadone and imipramine

methadone has been researched along with imipramine in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (65.91)	18.7374
1990's	5 (11.36)	18.2507
2000's	6 (13.64)	29.6817
2010's	4 (9.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Chang, TK; Ensom, MH; Kiang, TK	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Glen, RC; Lowe, R; Mitchell, JB	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Mason, MF	1
Cramer, H; Goodwin, FK; Post, RM	1
Gold, MS; Kleber, HD; Pottash, AL; Redmond, DE; Sweeney, DR	1
Brase, DA; Loh, HH	1
Anderson, MW; Eling, TE	1
Brady, R; Nunes, EV; Quitkin, FM; Stewart, JW	1
Wood, M	1
Baumann, P; Cuendet, C; Eap, CB	1
Cleary, J; Nader, M; Thompson, T	1
Anderson, MW; Eling, TE; Fouts, JR; Orton, TC; Pickett, RD	1
Anderson, MW; Eling, TE; Orton, TC; Pickett, RD	1
Weinstock, M	1
Ahtee, L; Kääriäinen, I	1
Ahtee, L; Jounela, AJ; Saarnivaara, L; Simola, I	1
Hartvig, P; Vessman, J	1
Bickel, MH; Steele, JW	1
Ciofalo, FR	1
Baden, MM; Valanju, NN; Valanju, SN; Verma, SK	1
Garriott, JC; Stolman, A	1
Irwin, S; Kinoi, R; Van Sloten, M; Workman, MP	1
Kreppel, E	1
Marshall, AS; Weinstock, M	1
Blumberg, AG; Heaton, AM	1
Pálosi, E; Szporny, L	1
Angioi, RM; Curreli, V; De Montis, GM; Devoto, P; Tagliamonte, A	1
Kleber, HD; Prusoff, BA; Riordan, CE; Rounsaville, BJ; Weissman, MM; Wilber, CH	1
Roszell, DK; Struger, J	1
Evans, BD; Marcovici, M; McLellan, AT; O'Brien, CP; Woody, GE	1
De Montis, GM; Devoto, P; Tagliamonte, A	1
Brady, R; Nunes, E; Post-Koenig, T; Quitkin, F	1
Cleary, J; Kovera, CA; Overmier, JB; Schaal, DW; Thompson, T	1
Brady, R; Deliyannides, D; Donovan, SJ; Koenig, T; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Woody, G	1
Boukef, MF; Duché, JC; Jolliet-Riant, P; Simon, N; Tillement, JP	1
SORENSEN, BF	1

Reviews

5 review(s) available for methadone and imipramine

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug impairment reviews: opiates, minor tranquilizers. NIDA research monograph, 1977, Volume: Series 11 Topics: Amitriptyline; Anti-Anxiety Agents; Automobile Driving; Behavior; Desipramine; Dextropropoxyphene; Diazepam; Ethanol; Humans; Imipramine; Lithium; Methadone; Motor Skills; Narcotics; Task Performance and Analysis	1977
Plasma drug binding: implications for anesthesiologists. Anesthesia and analgesia, 1986, Volume: 65, Issue:7 Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors	1986
Antidepressant treatment in methadone maintenance patients. Journal of addictive diseases, 1994, Volume: 13, Issue:3 Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Imipramine; Male; Methadone; Opioid-Related Disorders; Personality Inventory; Treatment Outcome	1994

Trials

2 trial(s) available for methadone and imipramine

Article	Year
Imipramine as treatment for depression in addicts. Archives of general psychiatry, 1983, Volume: 40, Issue:6 Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Methadone; Opioid-Related Disorders; Outcome and Process Assessment, Health Care; Placebos; Psychiatric Status Rating Scales	1983
Imipramine treatment of opiate-dependent patients with depressive disorders. A placebo-controlled trial. Archives of general psychiatry, 1998, Volume: 55, Issue:2 Topics: Adult; Comorbidity; Depressive Disorder; Diagnosis, Dual (Psychiatry); Double-Blind Method; Drug Therapy, Combination; Humans; Imipramine; Methadone; Models, Psychological; Opioid-Related Disorders; Patient Compliance; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; Self Medication; Treatment Outcome	1998

Article

Year

Imipramine as treatment for depression in addicts.

Archives of general psychiatry, 1983, Volume: 40, Issue:6

Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Methadone; Opioid-Related Disorders; Outcome and Process Assessment, Health Care; Placebos; Psychiatric Status Rating Scales

1983

Imipramine treatment of opiate-dependent patients with depressive disorders. A placebo-controlled trial.

Archives of general psychiatry, 1998, Volume: 55, Issue:2

Topics: Adult; Comorbidity; Depressive Disorder; Diagnosis, Dual (Psychiatry); Double-Blind Method; Drug Therapy, Combination; Humans; Imipramine; Methadone; Models, Psychological; Opioid-Related Disorders; Patient Compliance; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; Self Medication; Treatment Outcome

1998

Other Studies

37 other study(ies) available for methadone and imipramine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Cyclic AMP in cerebrospinal fluid of manic and depressive patients. Psychological medicine, 1977, Volume: 7, Issue:4 Topics: Administration, Oral; Amitriptyline; Bipolar Disorder; Cyclic AMP; Depression; Humans; Imipramine; Lithium; Methadone; Methyltyrosines; Physical Exertion; Probenecid; Tryptophan	1977
Rapid opiate detoxification: clinical evidence of antidepressant and antipanic effects of opiates. The American journal of psychiatry, 1979, Volume: 136, Issue:7 Topics: Adult; Anxiety; Clonidine; Depression; Drug Therapy, Combination; Fear; Humans; Imipramine; Male; Methadone; Narcotics; Panic; Substance Withdrawal Syndrome; Substance-Related Disorders	1979
Comparison of the inhibition of 5-hydroxytryptamine uptake by methadone and its congeners in human platelets. Biochemical pharmacology, 1976, Jul-15, Volume: 25, Issue:14 Topics: Blood Platelets; Clomipramine; Depression, Chemical; Humans; Imipramine; In Vitro Techniques; Kinetics; Methadone; Molecular Conformation; Serotonin	1976
Studies on the uptake, metabolism, and release of endogenous and exogenous chemicals by use of the isolated perfused lung. Environmental health perspectives, 1976, Volume: 16 Topics: Animals; Dextrans; Imipramine; In Vitro Techniques; Kinetics; Lung; Methadone; Methods; Perfusion; Polyethylene Glycols; Prostaglandins; Rabbits; Time Factors	1976
Imipramine treatment of methadone maintenance patients with affective disorder and illicit drug use. The American journal of psychiatry, 1991, Volume: 148, Issue:5 Topics: Adult; Cocaine; Depressive Disorder; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Imipramine; Male; Methadone; Pilot Projects; Substance Abuse, Intravenous; Substance-Related Disorders	1991
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2 Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine	1988
Effects of imipramine on responding reduced by methadone. Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:1 Topics: Animals; Columbidae; Conditioning, Operant; Drug Interactions; Drug Tolerance; Imipramine; Male; Methadone; Reinforcement Schedule; Time Factors	1986
Xenobiotic accumulation and metabolism by isolated perfused rabbit lungs. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:3 Topics: Amines; Amphetamine; Aniline Compounds; Animals; Carbon Isotopes; Dose-Response Relationship, Drug; Imidazoles; Imipramine; In Vitro Techniques; Lung; Male; Methadone; Organ Size; Paraquat; Pentobarbital; Perfusion; Piperazines; Rabbits; Time Factors	1973
Accumulation of amines in the isolated perfused rabbit lung. The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:2 Topics: Animals; Carbon Radioisotopes; Dextroamphetamine; Drug Interactions; Imidazoles; Imipramine; In Vitro Techniques; Lung; Methadone; Piperazines; Rabbits; Time Factors	1974
The role of the sympathetic nervous system in mediating the action of analgesic drugs on the lens. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2 Topics: Amitriptyline; Amphetamine; Animals; Bretylium Compounds; Cocaine; Dopamine; Ephedrine; Epinephrine; Guanethidine; Imipramine; Iproniazid; Lens, Crystalline; Metaraminol; Methadone; Mice; Nialamide; Norepinephrine; Phenylephrine; Reserpine; Sympathetic Nervous System; Synephrine	1968
5-hydroxytryptamine in platelets and brain of rabbits treated chronically with imipramine, morphine or methadone. Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 277, Issue:4 Topics: Animals; Blood Platelets; Brain Chemistry; Hydroxyindoleacetic Acid; Imipramine; Male; Methadone; Morphine; Rabbits; Serotonin; Time Factors	1973
Interactions of some analgesics and antidepressants with phenelzine or reserpine in the mouse. Pharmacology, 1974, Volume: 12, Issue:1 Topics: Alphaprodine; Analgesics; Animals; Antidepressive Agents; Body Temperature; Drug Interactions; Fenclonine; Hypothermia; Imipramine; Isonipecotic Acids; Lethal Dose 50; Male; Meperidine; Methadone; Mice; Pentazocine; Phenelzine; Reserpine; Time Factors	1974
Electron capture gas chromatography of tertiary amines after a demethylation reaction to secondary amines. II. Studies of different chloroformates and alternative hydrolysis procedures. Acta pharmaceutica Suecica, 1974, Volume: 11, Issue:2 Topics: Acylation; Amitriptyline; Chromatography, Gas; Diphenhydramine; Formates; Hydrocarbons, Brominated; Hydrocarbons, Chlorinated; Hydrolysis; Imipramine; Mass Spectrometry; Methadone; Methods; Methylamines; Propylamines; Time Factors	1974
Binding of basic and acidic drugs to rat tissue subcellular fractions. Chemico-biological interactions, 1974, Volume: 8, Issue:3 Topics: Animals; Binding Sites; Brain; Cell Nucleus; Chlorpromazine; Imipramine; Kidney; Kinetics; Liver; Lung; Male; Methadone; Microsomes; Mitochondria; Muscles; Organ Specificity; Phenylbutazone; Protein Binding; Rats; Receptors, Drug; Salicylates; Sulfadimethoxine; Warfarin	1974
Methadone inhibition of 3H-5-hydroxytryptamine uptake by synaptosomes. The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:1 Topics: Animals; Brain; Centrifugation, Density Gradient; Cold Temperature; Dinitrophenols; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Kinetics; Male; Methadone; Monoamine Oxidase Inhibitors; Morphine; Naloxone; Ouabain; Potassium Chloride; Rabbits; Serotonin; Serotonin Antagonists; Sucrose; Synaptosomes; Tritium	1974
Confirmed identification of biotransformed drugs of abuse in urine. American journal of clinical pathology, 1972, Volume: 57, Issue:1 Topics: Amphetamine; Analgesics; Barbiturates; Biotransformation; Caffeine; Cannabis; Chromatography, Gas; Chromatography, Thin Layer; Codeine; Humans; Hydrogen-Ion Concentration; Imipramine; Indicators and Reagents; Methadone; Morphine; Nicotine; Pharmaceutical Preparations; Procaine; Skin; Spectrum Analysis; Substance-Related Disorders; Tranquilizing Agents	1972
Detection of some psychotherapeutic drugs and their metabolites in urine. Clinical toxicology, 1971, Volume: 4, Issue:2 Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine	1971
Drug effects on distress-evoked behavior in mice: methodology and drug class comparisons. Psychopharmacologia, 1971, Volume: 20, Issue:2 Topics: Aggression; Animals; Arousal; Behavior, Animal; Chlordiazepoxide; Electric Stimulation; Electroshock; Ethanol; Foot; Humans; Imipramine; Locomotion; Methadone; Methamphetamine; Mice; Pentobarbital; Perphenazine; Vocalization, Animal	1971
[Principles and risks of drug treatment of pain]. Bibliotheca psychiatrica et neurologica, 1969, Volume: 139 Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans; Imipramine; Levallorphan; Levorphanol; Methadone; Morphine; Pain; Phenacetin; Phenylbutazone; Pyrazoles; Salicylamides; Salicylates; Sulfonic Acids	1969
The influence of the sympathetic nervous system on the action of drugs on the lens. The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:1 Topics: Animals; Blepharoptosis; Body Temperature; Cataract; Chlorpromazine; Female; Guanethidine; Imipramine; Methadone; Mice; Phenoxybenzamine; Phentolamine; Propranolol; Reserpine; Sympathectomy; Sympathetic Nervous System	1969
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs. Journal of chromatography, 1969, May-20, Volume: 41, Issue:3 Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine	1969
New, simple method for the informative investigation of sedatives. Psychopharmacologia, 1967, Volume: 12, Issue:1 Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Escape Reaction; Glutethimide; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Meprobamate; Methadone; Methods; Mice; Morphine; Nialamide; Pentobarbital; Phenobarbital; Reserpine; Tubocurarine; Urethane	1967
In utero exposure to methadone produces a stable decrease of the cortex 5-HT transport system in rats. European journal of pharmacology, 1983, May-20, Volume: 90, Issue:1 Topics: Animals; Biological Transport; Cerebral Cortex; Female; Imipramine; Methadone; Naloxone; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Serotonin; Serotonin; Synaptosomes	1983
Single case study: panic disorder associated with opioid dependency and methadone maintenance treatment. Drug and alcohol dependence, 1984, Volume: 13, Issue:3 Topics: Adult; Clorazepate Dipotassium; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fear; Heroin Dependence; Humans; Imipramine; Male; Methadone; Panic	1984
The use of antidepressants with methadone in depressed maintenance patients. Annals of the New York Academy of Sciences, 1982, Volume: 398 Topics: Depressive Disorder; Doxepin; Female; Humans; Imipramine; Male; Methadone; Middle Aged; Opioid-Related Disorders	1982
Possible antidepressant activity of methadone. European journal of pharmacology, 1982, Apr-08, Volume: 79, Issue:1-2 Topics: Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Imipramine; In Vitro Techniques; Membranes; Methadone; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Serotonin	1982
Behavioral and neurochemical mechanisms of opioid-antidepressant interactions. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:1 Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Columbidae; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Endorphins; Female; Imipramine; Methadone; Norepinephrine; Reinforcement Schedule	1994
The genetic variant A of human alpha 1-acid glycoprotein limits the blood to brain transfer of drugs it binds. Life sciences, 1998, Volume: 62, Issue:14 Topics: Animals; Blood-Brain Barrier; Chlorpromazine; Disopyramide; Genetic Variation; Humans; Imipramine; Male; Methadone; Mifepristone; Orosomucoid; Pharmacokinetics; Propranolol; Protein Binding; Rats; Rats, Wistar	1998
Skin symptoms in acute narcotic intoxication. Danish medical bulletin, 1963, Volume: 10 Topics: Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Meprobamate; Methadone; Narcotics; Pressure Ulcer	1963