methadone and haloperidol

methadone has been researched along with haloperidol in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (59.18)	18.7374
1990's	2 (4.08)	18.2507
2000's	8 (16.33)	29.6817
2010's	10 (20.41)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Evans, CA; Jolivette, LJ; Nagilla, R; Ward, KW	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ahtee, L; Kääriäinen, I	1
Segal, DS	1
Almasi, J; Carlson, KR	1
Extein, I; Gold, MS; Kleber, HD; Pottash, AL; Redmond, DE	1
Gianutsos, G; Lal, H; Puri, SK	1
Gessa, GL; Tagliamonte, A	1
Carlson, KR; Eibergen, RD	2
Rosecrans, JA; Spencer, RM	1
Gianutsos, G; Lal, H	1
D'Ambra, C; Garrity, F; Lord, D; Porres, JM	1
Henderson, GL; Westkaemper, R	1
Yanagita, T	1
Bero, LA; Kuhn, CM	1
Jori, A; Monti, E	1
Kerr, FW; Pozuelo, J	1
Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A	1
Clemens, JA; Sawyer, BD	1
Karkalas, J; Lal, H	1
Friedman, JJ; LeCompte, G; Sinacore, R	1
Lal, H; Puri, S	1
Garriott, JC; Stolman, A	1
Pálosi, E; Szporny, L	1
Carlson, KR; Seeger, TF	1
Cervo, L; Romandini, S; Samanin, R	1
Brocco, M; McMillan, DE	1
Breivik, H; Rennemo, F	1
Kleber, HD; Redmond, DE; Uhde, TW	1
Algeri, S; Consolo, S; Ladinsky, H; Ponzio, F; Samanin, R	1
Galynker, II; Levinson, I; Rosenthal, RN	1
Ho, TS; Pedersen-Bjergaard, S; Rasmussen, KE	1
Ebert, SN; Katchman, AN; Koerner, J; Tosaka, T; Woosley, RL	1
Bruera, E; Buckley, JS; Salpeter, SR	1
Hansen, SH; Jensen, H; Li, B; Payán, MD; Pedersen-Bjergaard, S; Petersen, NJ	1
Bruera, E; Buckley, JS; Buckley, NS; Salpeter, SR	1
Baeyens, JM; Cobos, EJ	1

Reviews

3 review(s) available for methadone and haloperidol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effect of methadone and dextromoramide on dopamine metabolism: comparison with haloperidol and amphetamine. Neuropharmacology, 1975, Volume: 14, Issue:12 Topics: Adenylyl Cyclases; Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Dextroamphetamine; Dextromoramide; Dopamine; Haloperidol; In Vitro Techniques; Methadone; Mice; Rats	1975
[Overview of the progress in drug dependence studies--mainly focussing on psychic dependence]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:2 Topics: Animals; Benzodiazepines; Haloperidol; Humans; Limbic System; Methadone; Naloxone; Receptors, Dopamine; Substance-Related Disorders	1992

Trials

1 trial(s) available for methadone and haloperidol

Article	Year
A comparison of haloperidol with methadone in blocking heroin-withdrawal symptoms. A pilot study. International pharmacopsychiatry, 1973, Volume: 8, Issue:4 Topics: Adolescent; Adult; Clinical Trials as Topic; Haloperidol; Heroin Dependence; Humans; Methadone; Pilot Projects; Substance Withdrawal Syndrome; Time Factors	1973

Other Studies

45 other study(ies) available for methadone and haloperidol

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Extrapolation of preclinical pharmacokinetics and molecular feature analysis of "discovery-like" molecules to predict human pharmacokinetics. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7 Topics: Animals; Biometry; Dogs; Drug Evaluation, Preclinical; Haloperidol; Haplorhini; Humans; Injections, Intravenous; Liver; Liver Circulation; Metabolic Clearance Rate; Mifepristone; Molecular Structure; Molecular Weight; Rats; Reproducibility of Results	2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5 Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine	2012
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Effect of narcotic analgesics on the striatal homovanillic acid content in mice; relation to antinociceptive effect. Medical biology, 1976, Volume: 54, Issue:1 Topics: Analgesics, Opioid; Animals; Body Temperature; Corpus Striatum; Cyclazocine; Haloperidol; Homovanillic Acid; Male; Methadone; Mice; Morphine; Pain; Pentazocine; Phenylacetates; Piperidines; Thebaine; Time Factors	1976
Some considerations regarding the characterization and interpretation of neuropeptide-induced behavioral changes. Neurosciences Research Program bulletin, 1978, Volume: 16, Issue:4 Topics: Animals; Behavior, Animal; Benzimidazoles; Dogs; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Haloperidol; Humans; Injections, Intravenous; Injections, Intraventricular; Methadone; Mice; Morphine; Motor Activity; Naloxone; Peptides; Rats; Time Factors	1978
Behavioral supersensitivity to apomorphine following chronic narcotic treatment in the guinea pig. Psychopharmacology, 1978, May-31, Volume: 57, Issue:3 Topics: Animals; Apomorphine; Behavior, Animal; Guinea Pigs; Haloperidol; Humans; Male; Methadone; Morphine; Stereotyped Behavior; Time Factors	1978
Decrease in serum prolactin by naloxone: evidence against antidopamine and antipsychotic effects. The American journal of psychiatry, 1979, Volume: 136, Issue:10 Topics: Animals; Haloperidol; Haplorhini; Humans; Macaca; Male; Methadone; Morphine; Naloxone; Opioid-Related Disorders; Prolactin; Psychotic Disorders; Receptors, Dopamine	1979
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity. Life sciences, 1975, Jul-01, Volume: 17, Issue:1 Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Dexetimide; Dextromoramide; Dogs; Dopamine; Drug Combinations; Haloperidol; Humans; Meperidine; Methadone; Mice; Morphine; Phenoperidine; Pimozide; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome; Tranquilizing Agents; Vomiting	1975
Dyskinesias in monkeys: interaction of methamphetamine with prior methadone treatment. Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2 Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methamphetamine; Naloxone; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Stereotyped Behavior	1976
Susceptibility to amphetamine-elicited dyskinesias following chronic methadone treatment in monkeys. Annals of the New York Academy of Sciences, 1976, Volume: 281 Topics: Animals; Chlorpromazine; Clozapine; Diazepam; Drug Interactions; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Macaca mulatta; Male; Methadone; Methamphetamine; Phenobarbital; Phentolamine; Physostigmine; Spiperone; Time Factors	1976
The discriminative stimulus properties of morphine in female rats chronically depleted of dopamine. Research communications in chemical pathology and pharmacology, 1977, Volume: 17, Issue:1 Topics: Animals; Brain Chemistry; Discrimination Learning; Discrimination, Psychological; Dopamine; Dose-Response Relationship, Drug; Female; Generalization, Stimulus; Haloperidol; Methadone; Morphine; Norepinephrine; Rats; Stimulation, Chemical; Time Factors	1977
Effect of loperamide, haloperidol and methadone in rats trained to discriminate morphine from saline. Psychopharmacologia, 1975, Volume: 41, Issue:3 Topics: Animals; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Haloperidol; Male; Methadone; Morphine; Piperidines; Rats; Reinforcement Schedule; Sodium Chloride	1975
Comparison of eight kits for the diagnosis of pregnancy. American journal of clinical pathology, 1975, Volume: 64, Issue:4 Topics: Chlorpromazine; Chorionic Gonadotropin; Evaluation Studies as Topic; False Negative Reactions; False Positive Reactions; Female; Haloperidol; Humans; Methadone; Pregnancy; Pregnancy Tests, Immunologic; Proteinuria; Psychotropic Drugs; Thioridazine	1975
Stereotypy following acute administration of l-alpha-acetylmethadol (LAAM) in the rat. Proceedings of the Western Pharmacology Society, 1975, Volume: 18 Topics: Amphetamine; Animals; Apomorphine; Behavior; Drug Interactions; Haloperidol; Humans; Male; Methadone; Methadyl Acetate; Methyltyrosines; Naloxone; Rats; Stereotyped Behavior	1975
Catecholaminergic regulation of opiate-stimulated growth hormone secretion in the developing rat. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:1 Topics: Animals; Catecholamines; Cyproheptadine; Dopamine; Growth Hormone; Haloperidol; Methadone; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Reserpine; Serotonin; Sympatholytics	1986
Different sensitivity to drugs eliciting homovanillic acid increase in two strains of mice. The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:12 Topics: Animals; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Diethylpropion; Female; Fenfluramine; Haloperidol; Homovanillic Acid; Methadone; Methamphetamine; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Phenylacetates; Species Specificity; Stimulation, Chemical	1974
Suppression of craving and other signs of dependence in morphine-addicted monkeys by administration of alpha-methyl-para-tyrosine. Mayo Clinic proceedings, 1972, Volume: 47, Issue:9 Topics: Animals; Female; Fenclonine; Haloperidol; Haplorhini; Humans; Hypothalamus; Injections, Intravenous; Macaca; Methadone; Methyltyrosines; Morphine; Nalorphine; Septal Nuclei; Substance Withdrawal Syndrome; Substance-Related Disorders; Thioridazine; Trifluoperazine	1972
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action. British journal of pharmacology, 1974, Volume: 51, Issue:2 Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus	1974
Evidence that methadone stimulates prolactin release by dopamine receptor blockade. Endocrine research communications, 1974, Volume: 1, Issue:4 Topics: Animals; Apomorphine; Chlorpromazine; Dopamine; Haloperidol; Male; Methadone; Prolactin; Rats; Receptors, Drug	1974
Non-addictive drug antagonist program in a community setting. American journal of public health, 1973, Volume: 63, Issue:9 Topics: Adolescent; Adult; Age Factors; Allied Health Personnel; Ambulatory Care; Community Health Services; Drug Antagonism; Haloperidol; Heroin Dependence; Humans; Methadone; New York; Personality Inventory; Pharmaceutical Preparations; Physical Examination; Psychiatric Status Rating Scales; Psychological Tests; Social Adjustment; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Urban Population; Vocational Guidance	1973
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression. Psychopharmacologia, 1973, Volume: 32, Issue:2 Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Methadone; Methyltyrosines; Morphine Dependence; Premedication; Rats; Substance Withdrawal Syndrome	1973
Detection of some psychotherapeutic drugs and their metabolites in urine. Clinical toxicology, 1971, Volume: 4, Issue:2 Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine	1971
New, simple method for the informative investigation of sedatives. Psychopharmacologia, 1967, Volume: 12, Issue:1 Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Escape Reaction; Glutethimide; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Meprobamate; Methadone; Methods; Mice; Morphine; Nialamide; Pentobarbital; Phenobarbital; Reserpine; Tubocurarine; Urethane	1967
Interaction of opiates with dopamine receptors: receptor binding and behavioral assays. Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:1 Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butaclamol; Dibenzocycloheptenes; Haloperidol; Kinetics; Male; Methadone; Morphine; Naloxone; Rats; Receptors, Dopamine; Spiperone	1982
Evidence of serotonin-dopamine involvement in the inhibition of d-amphetamine stereotypy and appearance of stereotyped movements found respectively after acute and long-term treatment with morphine and methadone in rats. Life sciences, 1981, Dec-21, Volume: 29, Issue:25 Topics: Animals; Brain; Dextroamphetamine; Dopamine; Fenclonine; Fenfluramine; Haloperidol; Humans; Male; Methadone; Methylphenidate; Morphine; Piperazines; Rats; Serotonin; Stereotyped Behavior	1981
Modification of drug effects by l-alpha-acetylmethadol. Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:4 Topics: Animals; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Male; Methadone; Methadyl Acetate; Morphine; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains	1984
Clinical evaluation of combined treatment with methadone and psychotropic drugs in cancer patients. Acta anaesthesiologica Scandinavica. Supplementum, 1982, Volume: 74 Topics: Adult; Aged; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Psychotropic Drugs; Time Factors	1982
Psychosis in the opioid addicted patient: assessment and treatment. The Journal of clinical psychiatry, 1982, Volume: 43, Issue:6 Topics: Adult; Chlorpromazine; Diagnosis, Differential; Double-Blind Method; Haloperidol; Heroin Dependence; Humans; Male; Methadone; Psychoses, Substance-Induced; Substance Withdrawal Syndrome	1982
Long-term effects of haloperidol, Clozapine, and methadone on rat striatal cholinergic and dopaminergic dynamics. Advances in biochemical psychopharmacology, 1980, Volume: 24 Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Drug Tolerance; Haloperidol; Homovanillic Acid; Male; Methadone; Neurons; Parasympathetic Nervous System; Rats	1980
Methadone withdrawal psychosis. The Journal of clinical psychiatry, 1995, Volume: 56, Issue:2 Topics: Adult; Female; Follow-Up Studies; Haloperidol; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Perphenazine; Psychoses, Substance-Induced; Substance Withdrawal Syndrome	1995
Liquid-phase microextraction of protein-bound drugs under non-equilibrium conditions. The Analyst, 2002, Volume: 127, Issue:5 Topics: Amphetamine; Haloperidol; Humans; Meperidine; Methadone; Microchemistry; Pharmaceutical Preparations; Promethazine; Proteins	2002
Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:3 Topics: Animals; Arsenic Trioxide; Arsenicals; Cells, Cultured; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Haloperidol; Humans; Loratadine; Lovastatin; Methadone; Oxides; Pentamidine; Potassium Channel Blockers; Rabbits; Terfenadine; Torsades de Pointes	2006
The use of very-low-dose methadone for palliative pain control and the prevention of opioid hyperalgesia. Journal of palliative medicine, 2013, Volume: 16, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; California; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Haloperidol; Hospice Care; Humans; Hyperalgesia; Male; Medical Audit; Methadone; Middle Aged; N-Methylaspartate; Pain Management; Retrospective Studies	2013
Nano-electromembrane extraction. Analytica chimica acta, 2013, Jun-27, Volume: 785 Topics: Electricity; Electrophoresis, Capillary; Ethers; Haloperidol; Loperamide; Membranes, Artificial; Meperidine; Methadone; Nanotechnology; Nortriptyline; Sodium Chloride; Solutions; Sulfates; Water	2013
The use of very-low-dose methadone and haloperidol for pain control in the hospital setting: a preliminary report. Journal of palliative medicine, 2015, Volume: 18, Issue:2 Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; California; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Male; Methadone; Middle Aged; Morphine; Pain; Pain Management; Palliative Care; Retrospective Studies	2015
Use of Very-Low-Dose Methadone and Haloperidol for Pain Control in Palliative Care Patients: Are the Sigma-1 Receptors Involved? Journal of palliative medicine, 2015, Volume: 18, Issue:8 Topics: Analgesics, Opioid; Female; Haloperidol; Humans; Male; Methadone; Morphine; Pain; Pain Management; Palliative Care	2015