methadone has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blake, AD; Bot, G; Freeman, JC; Reisine, T | 1 |
| Gong, ZH; Liao, XP; Liu, JG; Qin, BY | 1 |
| Bylund, DB; Happe, HK; Murrin, LC | 1 |
| Belcheva, MM; Clark, AL; Coscia, CJ; Hou, Y; Tan, Y; Zahm, DS | 1 |
| Childers, SR; Kahn, WR; Martin, TJ; Xiao, R | 1 |
| He, L; Whistler, JL | 1 |
| Bailey, CP; Braksator, E; Goodchild, S; Henderson, G; Kelly, E; Marrion, NV; Rodriguez-Martin, I | 1 |
| Ingram, SL; Lamberts, JT; Li, MH; Neubig, RR; Smith, CE; Traynor, JR | 1 |
8 other study(ies) available for methadone and guanosine 5'-o-(3-thiotriphosphate)
| Article | Year |
|---|---|
Differential opioid agonist regulation of the mouse mu opioid receptor.
Topics: Adenylate Cyclase Toxin; Analgesics; Animals; Buprenorphine; Colforsin; Cyclic AMP; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Levorphanol; Methadone; Mice; Morphine; Pertussis Toxin; Receptors, Opioid, mu; Virulence Factors, Bordetella | 1997 |
Methadone-induced desensitization of the delta-opioid receptor is mediated by uncoupling of receptor from G protein.
Topics: Animals; CHO Cells; Cricetinae; Cyclic AMP; Down-Regulation; Drug Interactions; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Methadone; Morphine; Neuroblastoma; Protein Binding; Rats; Receptors, Opioid, delta; Time Factors; Tumor Cells, Cultured | 1999 |
Agonist-stimulated [35S]GTPgammaS autoradiography: optimization for high sensitivity.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Animals; Autoradiography; Binding, Competitive; Brain; Buffers; Dithiothreitol; Dose-Response Relationship, Drug; Epinephrine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Magnesium; Methadone; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Sensitivity and Specificity; Serotonin; Serotonin Receptor Agonists; Sodium Chloride; Sulfur Radioisotopes; Time Factors; Xanthines | 2001 |
Differential effects of gestational buprenorphine, naloxone, and methadone on mesolimbic mu opioid and ORL1 receptor G protein coupling.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Autoradiography; Buprenorphine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Limbic System; Male; Methadone; Naloxone; Nociceptin Receptor; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Opioid; Receptors, Opioid, mu; Sex Factors; Sulfur Isotopes | 2004 |
Differential regional effects of methadone maintenance compared to heroin dependence on mu-opioid receptor desensitization in rat brain.
Topics: Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Eating; Guanosine 5'-O-(3-Thiotriphosphate); Heroin; Heroin Dependence; Injections, Intravenous; Male; Methadone; Narcotics; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, G-Protein-Coupled; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration | 2007 |
The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics, Opioid; Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Methadone; Morphine; Morphine Dependence; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2007 |
Methadone: does it really have low efficacy at micro-opioid receptors?
Topics: Animals; Animals, Newborn; Cell Line, Transformed; Drug Interactions; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Locus Coeruleus; Membrane Potentials; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Protein Binding; Rats; Receptors, Opioid, mu; Transfection | 2008 |
Differential control of opioid antinociception to thermal stimuli in a knock-in mouse expressing regulator of G-protein signaling-insensitive Gαo protein.
Topics: Analgesics, Opioid; Animals; Brain; Diprenorphine; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Humans; Hyperalgesia; Inhibitory Postsynaptic Potentials; Isotopes; Male; Methadone; Mice; Mice, Transgenic; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Pain Measurement; Patch-Clamp Techniques; Pertussis Toxin; Protein Binding; Reaction Time; RGS Proteins; Signal Transduction; Spinal Cord | 2013 |