methadone and fluvoxamine

methadone has been researched along with fluvoxamine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (46.67)18.2507
2000's3 (20.00)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baettig, D; Baumann, P; Bertschy, G; Eap, CB1
Baumann, P; Bertschy, G; Eap, CB; Powell, K2
Bardou, LG; Berthou, F; Dréano, Y; Iribarne, C; Ménez, JF1
Berthou, F; Dréano, Y; Iribarne, C; Picart, D1
Alderman, CP; Frith, PA1
DeMaria, PA; Serota, RD1
Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO1
Gibert-Rahola, J; Mico, JA; Rojas-Corrales, MO1
Barak, Y; Baratz-Goldstein, R; Hostovsky, A; Pick, CG; Rubovitch, V; Schreiber, S; Volis, I1

Reviews

1 review(s) available for methadone and fluvoxamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for methadone and fluvoxamine

ArticleYear
Fluvoxamine and fluoxetine do not interact in the same way with the metabolism of the enantiomers of methadone.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:2

    Topics: Fluoxetine; Fluvoxamine; Humans; Methadone; Narcotics; Selective Serotonin Reuptake Inhibitors; Statistics, Nonparametric; Stereoisomerism; Substance-Related Disorders

1997

Other Studies

13 other study(ies) available for methadone and fluvoxamine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
Probable metabolic interaction between methadone and fluvoxamine in addict patients.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:1

    Topics: Adult; Depressive Disorder; Drug Interactions; Female; Fluvoxamine; Humans; Male; Methadone; Opioid-Related Disorders

1994
Fluoxetine addition to methadone in addicts: pharmacokinetic aspects.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:5

    Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Drug Interactions; Female; Fluoxetine; Fluvoxamine; Humans; Male; Methadone; Mood Disorders; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders

1996
Interaction of methadone with substrates of human hepatic cytochrome P450 3A4.
    Toxicology, 1997, Feb-14, Volume: 117, Issue:1

    Topics: Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Diazepam; Fluvoxamine; Humans; Methadone; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Rifampin

1997
In vitro interactions between fluoxetine or fluvoxamine and methadone or buprenorphine.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2

    Topics: Buprenorphine; Cytochrome P-450 Enzyme System; Fluoxetine; Fluvoxamine; Humans; In Vitro Techniques; Linear Models; Methadone; Microsomes, Liver; Narcotic Antagonists; Narcotics; Selective Serotonin Reuptake Inhibitors

1998
Fluvoxamine-methadone interaction.
    The Australian and New Zealand journal of psychiatry, 1999, Volume: 33, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Interactions; Female; Fluvoxamine; Humans; Hypercapnia; Hypoxia; Methadone; Narcotics; Substance-Related Disorders

1999
A therapeutic use of the methadone fluvoxamine drug interaction.
    Journal of addictive diseases, 1999, Volume: 18, Issue:4

    Topics: Adult; Drug Interactions; Female; Fluvoxamine; Humans; Methadone; Narcotics; Opioid-Related Disorders; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome

1999
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols; Desipramine; Fluvoxamine; Levorphanol; Male; Methadone; Mice; Morphine; Narcotics; Reserpine; Stereoisomerism; Time Factors; Tramadol; Venlafaxine Hydrochloride

2004
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior.
    Psychopharmacology, 2007, Volume: 190, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Indophenol; Levorphanol; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Stereotyped Behavior; Tics; Tourette Syndrome; Tramadol; Triazoles

2007
Interaction of different antidepressants with acute and chronic methadone in mice, and possible clinical implications.
    Journal of molecular neuroscience : MN, 2014, Volume: 52, Issue:4

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Citalopram; Clomipramine; Cyclohexanols; Desipramine; Drug Interactions; Fluvoxamine; Male; Methadone; Mice; Mice, Inbred ICR; Morpholines; Nociception; Pain Threshold; Reboxetine; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride

2014