methadone and fluoxetine

methadone has been researched along with fluoxetine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's13 (44.83)18.2507
2000's7 (24.14)29.6817
2010's8 (27.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Nagashima, R; Nishikawa, T; Tobita, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brooke, D; Fudala, PJ; Johnson, RE1
Batki, SL; Dumontet, R; Jacob, P; Jones, RT; Manfredi, LB; Sorensen, JL1
Pollack, MH; Rosenbaum, JF1
Smith, DF1
Creson, D; Davis, C; Elk, R; Grabowski, J; Kirby, K; Rhoades, H; Schmitz, J1
Carroll, K; Cushing, G; Gordon, L; Petrakis, I; Rounsaville, B1
Balon, R1
Batki, SL; Jacob, P; Jones, RT; Manfredi, LB1
Baumann, P; Bertschy, G1
Baumann, P; Bertschy, G; Eap, CB; Powell, K2
Berthou, F; Dréano, Y; Iribarne, C; Picart, D1
Creson, D; Elk, R; Grabowski, J; Hussein, I; Rhoades, HM; Schmitz, JM1
Carroll, KM; Gordon, L; Kosten, T; Nich, C; Petrakis, I; Rounsaville, B1
Bell, J; Christie, MJ; Dean, AJ; Mascord, DJ; Parker, G1
Calleri, E; Cherkaoui, S; Geiser, L; Prat, J; Rudaz, S; Veuthey, JL1
Haining, RL; Yu, AM1
Marchi, I; Rudaz, S; Selman, M; Veuthey, JL1
Greenwald, MK1
Bigelow, GE; Johnson, RE; Silverman, K; Strain, EC; Winstanley, EL1
Kukanich, B; Kukanich, KS; Rodriguez, JR1
Atayee, RS; Best, BM; Luk, S; Ma, JD1
KuKanich, B; KuKanich, K1

Reviews

1 review(s) available for methadone and fluoxetine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

9 trial(s) available for methadone and fluoxetine

ArticleYear
Weighing up the pros and cons: help-seeking by drug misusers in Baltimore, USA.
    Drug and alcohol dependence, 1992, Volume: 31, Issue:1

    Topics: Adult; Bromocriptine; Buprenorphine; Cocaine; Desipramine; Fear; Female; Fluoxetine; Humans; Male; Methadone; Middle Aged; Motivation; Opioid-Related Disorders; Patient Acceptance of Health Care; Phencyclidine Abuse; Substance Abuse Treatment Centers; Substance-Related Disorders; Urban Population

1992
Fluoxetine is ineffective for treatment of cocaine dependence or concurrent opiate and cocaine dependence: two placebo-controlled double-blind trials.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:3

    Topics: Adult; Cocaine; Demography; Double-Blind Method; Female; Fluoxetine; Humans; Male; Methadone; Opioid-Related Disorders; Psychiatric Status Rating Scales

1995
Fluoxetine for cocaine dependence in methadone maintenance: quantitative plasma and urine cocaine/benzoylecgonine concentrations.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:4

    Topics: Adult; Cocaine; Female; Fluoxetine; Humans; Male; Methadone; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Substance-Related Disorders

1993
Medication take-home doses and contingency management.
    Experimental and clinical psychopharmacology, 1998, Volume: 6, Issue:2

    Topics: Adult; Cocaine-Related Disorders; Female; Fluoxetine; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders

1998
Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts.
    Drug and alcohol dependence, 1998, May-01, Volume: 50, Issue:3

    Topics: Adult; Antidepressive Agents, Second-Generation; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Depression; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Heroin; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders; Substance Abuse Detection; Treatment Outcome

1998
Fluvoxamine and fluoxetine do not interact in the same way with the metabolism of the enantiomers of methadone.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:2

    Topics: Fluoxetine; Fluvoxamine; Humans; Methadone; Narcotics; Selective Serotonin Reuptake Inhibitors; Statistics, Nonparametric; Stereoisomerism; Substance-Related Disorders

1997
A randomised, controlled trial of fluoxetine in methadone maintenance patients with depressive symptoms.
    Journal of affective disorders, 2002, Volume: 72, Issue:1

    Topics: Adult; Antidepressive Agents; Comorbidity; Depression; Female; Fluoxetine; Humans; Male; Methadone; Narcotics; Patient Compliance; Substance-Related Disorders

2002
A randomized controlled trial of fluoxetine in the treatment of cocaine dependence among methadone-maintained patients.
    Journal of substance abuse treatment, 2011, Volume: 40, Issue:3

    Topics: Adult; Cocaine-Related Disorders; Double-Blind Method; Female; Fluoxetine; Humans; Male; Methadone; Middle Aged; Motivation; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Selective Serotonin Reuptake Inhibitors; Substance Abuse Detection; Time Factors; Token Economy; Treatment Outcome

2011
The effects of concurrent administration of cytochrome P-450 inhibitors on the pharmacokinetics of oral methadone in healthy dogs.
    Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:3

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Area Under Curve; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Therapy, Combination; Female; Fluoxetine; Ketoconazole; Male; Methadone; Prospective Studies; Trimethoprim

2011

Other Studies

19 other study(ies) available for methadone and fluoxetine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
Fluoxetine for cocaine abuse in methadone patients: preliminary findings.
    NIDA research monograph, 1990, Volume: 105

    Topics: Adult; Cocaine; Female; Fluoxetine; Heroin Dependence; Humans; Male; Methadone; Substance-Related Disorders

1990
Fluoxetine treatment of cocaine abuse in heroin addicts.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:1

    Topics: Adult; Cocaine; Female; Fluoxetine; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; Substance Abuse, Intravenous; Substance-Related Disorders

1991
The stereoselectivity of serotonin uptake in brain tissue and blood platelets: the topography of the serotonin uptake area.
    Neuroscience and biobehavioral reviews, 1986,Spring, Volume: 10, Issue:1

    Topics: Alanine; Amphetamine; Aniline Compounds; Animals; Antidepressive Agents; Blood Platelets; Brain; Fluoxetine; Humans; Male; Methadone; Mianserin; Mirtazapine; Morpholines; Naphthalenes; Nefopam; Nomifensine; Paroxetine; Piperidines; Rabbits; Serotonin; Stereoisomerism; Tranylcypromine; Viloxazine; Zimeldine

1986
Fluoxetine treatment for dually diagnosed methadone maintained opioid addicts: a pilot study.
    Journal of addictive diseases, 1994, Volume: 13, Issue:3

    Topics: Adult; Cocaine; Combined Modality Therapy; Comorbidity; Depressive Disorder; Diagnosis, Dual (Psychiatry); Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Methadone; Opioid-Related Disorders; Patient Compliance; Personality Inventory; Psychotherapy; Substance Abuse Detection; Substance-Related Disorders

1994
Fluoxetine for cocaine dependence in methadone maintenance.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:5

    Topics: Alcoholism; Cocaine; Dopamine Uptake Inhibitors; Drug Synergism; Fluoxetine; Heroin Dependence; Humans; Methadone; Substance Abuse Detection; Substance-Related Disorders

1994
Vulnerability to fluoxetine-induced indifference syndrome among opiate addicts: a case report.
    Biological psychiatry, 1995, Sep-15, Volume: 38, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Fluoxetine; Humans; Male; Methadone; Mood Disorders; Narcotics; Opioid-Related Disorders

1995
Fluoxetine addition to methadone in addicts: pharmacokinetic aspects.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:5

    Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Drug Interactions; Female; Fluoxetine; Fluvoxamine; Humans; Male; Methadone; Mood Disorders; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders

1996
In vitro interactions between fluoxetine or fluvoxamine and methadone or buprenorphine.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2

    Topics: Buprenorphine; Cytochrome P-450 Enzyme System; Fluoxetine; Fluvoxamine; Humans; In Vitro Techniques; Linear Models; Methadone; Microsomes, Liver; Narcotic Antagonists; Narcotics; Selective Serotonin Reuptake Inhibitors

1998
Infinite enantiomeric resolution of basic compounds using highly sulfated cyclodextrin as chiral selector in capillary electrophoresis.
    Electrophoresis, 2003, Volume: 24, Issue:15

    Topics: Cyclodextrins; Cyclohexanols; Electrophoresis, Capillary; Fluoxetine; Mass Spectrometry; Methadone; Stereoisomerism; Tramadol; Venlafaxine Hydrochloride

2003
Expression, purification, and characterization of mouse CYP2d22.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Amino Acid Sequence; Animals; Baculoviridae; Cell Line; Cloning, Molecular; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dealkylation; Dextromethorphan; Enzyme Inhibitors; Fluoxetine; Insecta; Ketoconazole; Kinetics; Methadone; Mice; Molecular Sequence Data; Molecular Weight; Quinidine; Sequence Homology, Amino Acid; Substrate Specificity

2006
Evaluation of the influence of protein precipitation prior to on-line SPE-LC-API/MS procedures using multivariate data analysis.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Jan-15, Volume: 845, Issue:2

    Topics: Alanine; Blood Proteins; Chemical Precipitation; Cholecalciferol; Chromatography, Liquid; Flunitrazepam; Fluoxetine; Mass Spectrometry; Methadone; Multivariate Analysis; Online Systems; Pyrrolidines; Solid Phase Extraction

2007
Behavioral economic analysis of drug preference using multiple choice procedure data.
    Drug and alcohol dependence, 2008, Jan-11, Volume: 93, Issue:1-2

    Topics: Choice Behavior; Economics; Fentanyl; Fluoxetine; Hallucinogens; Humans; Hydromorphone; Injections, Intramuscular; Methadone; Models, Psychological; Motivation; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Narcotics; Psychotropic Drugs; Recreation; Selective Serotonin Reuptake Inhibitors; Substance Abuse, Intravenous; Substance-Related Disorders

2008
Urinary diazepam metabolite distribution in a chronic pain population.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chronic Pain; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diazepam; Drug Interactions; Esomeprazole; Female; Fluoxetine; Humans; Male; Methadone; Nordazepam; Oxazepam; Retrospective Studies; Specimen Handling; Temazepam

2014
Chloramphenicol significantly affects the pharmacokinetics of oral methadone in Greyhound dogs.
    Veterinary anaesthesia and analgesia, 2015, Volume: 42, Issue:6

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Chloramphenicol; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Interactions; Female; Fluoxetine; Ketoconazole; Male; Medetomidine; Methadone; Trimethoprim

2015