methadone has been researched along with fentanyl in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (16.92) | 18.7374 |
| 1990's | 15 (7.69) | 18.2507 |
| 2000's | 54 (27.69) | 29.6817 |
| 2010's | 63 (32.31) | 24.3611 |
| 2020's | 30 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Bodinier, MC; Bonnet, B; Chapelain, B; Déprez, B; Eckhoff, C; Horvath, D; Poulain, R | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Creese, I; Feinberg, AP; Snyder, SH | 1 |
| Govoni, S; Kumakura, K; Spano, PF; Tonon, GC; Trabucchi, M | 1 |
| Lumb, WV; Pippi, NL | 1 |
| Leander, JD | 1 |
| Prianishnikova, NT; Tolstikova, GV | 1 |
| Colpaert, FC; Janssen, PA; Lal, H; Niemegeers, CJ | 1 |
| de Leon-Casasola, OA; Lema, MJ | 1 |
| Negus, SS; Picker, MJ; Powell, KR | 1 |
| Doty, P; Dykstra, LA; Mattox, SR; Negus, SS; Picker, MJ | 1 |
| Adams, JU; Holtzman, SG; Paronis, CA | 1 |
| Foley, KM; Houde, RW; Inturrisi, CE; Moulin, DE; Nip, TJ; Reidenberg, B; Wallenstein, S; Weinberg, DS | 1 |
| Koren, G; Maurice, L | 1 |
| Deshpande, JK; Maxwell, LG; Yaster, M | 1 |
| Blancquaert, JP; Lefebvre, RA; Willems, JL | 1 |
| Dykstra, LA; Massie, CA | 1 |
| Harty, GJ; Onofrio, BM; Yaksh, TL | 1 |
| Hynes, MD; Leander, JD; Reel, JK; Zimmerman, DM | 1 |
| Wood, M | 1 |
| Dykstra, LA; Picker, M | 1 |
| Terenius, L | 1 |
| Röthig, J | 1 |
| Herz, A; Hess, R; Teschemacher, H; von Cube, B | 1 |
| Vandam, LD | 1 |
| Montel, H; Starke, K | 1 |
| Dundee, JW; Loan, WB; Morrison, JD | 1 |
| Bauer, H; Konzett, H | 1 |
| Fujimoto, FM; Inturrisi, CE | 1 |
| Amsterdam, EA; Henderson, GL; Mason, DT; Rendig, SV | 1 |
| Pybus, DA; Torda, TA | 1 |
| Blazsó, G; Minker, E; Végh, A | 1 |
| Cousins, MJ; Gourlay, GK | 1 |
| Kehlet, H | 1 |
| Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE | 1 |
| Benowitz, N; Gordon, NC; Levine, J; Poole, T | 1 |
| Allen, MC; Baldwin, D; Bullingham, RE; McQuay, HJ; Moore, RA; Symonds, HW | 1 |
| Leander, JD; McCleary, PE | 1 |
| Tung, AS; Yaksh, TL | 1 |
| Birmingham, PK | 1 |
| Deshpande, JK; Gregory, DF; Tobias, JD | 1 |
| De Conno, F; Polastri, D | 1 |
| Braithwaite, RA; Jarvie, DR; Simpson, D; Stewart, MJ; Walker, S; Watson, IW; Widdop, B | 1 |
| Fuentes-Bellido, JG; López-Cebollada, J; Lorenzo-Foz, JP; Prieto-Alvarez, MP | 1 |
| Briggs, SL; Rech, RH; Sawyer, DC | 1 |
| Cheung, P; Li, JG; Liu-Chen, LY; Raffa, RB; Tzeng, TB | 1 |
| Morgan, D; Picker, MJ | 1 |
| Ashby, MA; Jackson, KA; Martin, P | 1 |
| Mercadante, S | 2 |
| Cano del Pozo, MI; Carvajal, A; García del Pozo, J; Martín Arias, LH; Rueda de Castro, AM | 1 |
| Sutherland, J; Walker, EA; Young, AM; Zhang, L | 1 |
| Arcuri, E; Centulio, F; Ciocca, F; D'Angiolino, G; Ginobbi, P; Marcelli, ME; Pelagalli, L; Tirelli, W | 1 |
| Casas, JR; Cherny, N; Conno, F; Hanks, GW; Hanna, M; Kalso, E; McQuay, HJ; Mercadante, S; Meynadier, J; Poulain, P; Radbruch, L; Ripamonti, C; Sawe, J; Twycross, RG; Ventafridda, V | 1 |
| del Castillo, LP; del Rosario, MA; Feria, M; Martín, AS; Ortega, JJ | 1 |
| van der Weide, M; Vielvoye-Kerkmeer, AP | 1 |
| Burgess, FW | 1 |
| Fischberg, DJ; Khojainova, N; Kornick, C; Manfredi, P; Payne, R; Primavera, LH; Santiago-Palma, J | 1 |
| Cash, J; Lugo, RA; MacLaren, R; Pribble, CG; Vernon, DD | 1 |
| Derby, S; Fischberg, D; Kornick, C; Manfredi, PL; Moryl, N; Payne, R; Santiago-Palma, J | 1 |
| Holtzman, SG | 1 |
| Barrett, AC; Picker, MJ; Smith, ES | 1 |
| Aibak, H; Beaudet, A; Cahill, CM; Collier, B; Esdaile, MJ; Kieffer, BL; Morinville, A | 1 |
| Cimino, M; Fletcher, JE; Heard, AM; Heard, CM; Kielma, D; Siddappa, R | 1 |
| Dagenais, C; Graff, CL; Pollack, GM | 1 |
| Wootton, M | 1 |
| Campa, T; De Conno, F; Ripamonti, C | 1 |
| Bowdle, TA; Even, A; Shen, DD; Swardstrom, M | 1 |
| Shaiova, L; Wallenstein, D | 1 |
| Carrougher, GJ; Engrav, LH; Friedrich, JB; Gibran, NS; Heckbert, SR; Heimbach, DM; Honari, S; Klein, MB; Lezotte, DC; Round, KA; Sullivan, SR; Wiechman, SA | 1 |
| Greenwald, MK; Roehrs, TA | 1 |
| Benítez-Rosario, MA; Feria, M; Martín-Ortega, JJ; Martínez-Castillo, LP; Salinas-Martín, A | 1 |
| Arcuri, E; Arese, M; Bacchi, A; Cardelli, P; Citro, G; Mastronicola, D; Mercadante, S; Sarti, P | 1 |
| Greenwald, MK | 2 |
| Biswas, AK; Davis, DH; Feldman, BL; Zintz, EA | 1 |
| Jung, BF; Reidenberg, MM | 1 |
| Sachdeva, DK; Stadnyk, JM | 1 |
| Casuccio, A; Ferrera, P; Mercadante, S; Villari, P | 1 |
| Tobias, JD; Wheeler, AD | 1 |
| Allen, JW; Horais, KA; Tozier, NA; Yaksh, TL | 1 |
| Berdine, HJ; Nesbit, SA | 1 |
| Buechler, NL; Eisenach, JC; Kim, SA; Martin, TJ; Porreca, F | 1 |
| Reid, C | 1 |
| Casuccio, A; Ferrera, P; Gambaro, V; Mercadante, S; Villari, P | 1 |
| Arbuckle, R; Bruera, E; Curry, EA; Hung, F; Palla, S | 1 |
| Benvenuto, A; Howard, D; Meyer, M; Plante, D; Wagner, K | 1 |
| Angst, MS; Davis, MP; Shaiova, LA | 1 |
| Friedrichsdorf, SJ; Kang, TI | 1 |
| Coulter, C; Crompton, K; Marinetti, L; Moore, C | 1 |
| Aielli, F; Casuccio, A; Ferrera, P; Ficorella, C; Fulfaro, F; Gebbia, V; Mangione, S; Mercadante, S; Porzio, G; Riina, S; Verna, L; Villari, P | 1 |
| Benyamin, R; Glaser, SE; Hansen, H; Manchikanti, L; Patel, S; Trescot, AM | 1 |
| Mathieu, N; Tuna, T | 1 |
| Flanigan, KM; Schenkenberg, T; Shprecher, DR; Smith, AG; Smith, SM; Steffens, J | 1 |
| Anderson, BJ; Craig, F; Michel, E; Zernikow, B | 1 |
| Casuccio, A; Ferrera, P; Intravaia, G; Mangione, S; Mercadante, S; Villari, P | 1 |
| Quigley, C | 1 |
| Baud, FJ; Chevillard, L; Mégarbane, B; Risède, P | 1 |
| Hack, RA; Lynch, RE | 1 |
| Bohn, LM; Raehal, KM | 1 |
| Arcuri, E; Ferrera, P; Mercadante, S | 1 |
| Buchanan, D | 1 |
| Bowens, CD; Breitzka, RL; Sheeran, PW; Thompson, DG; Thompson, JA; Thompson, MT | 1 |
| de Santos, P; Mercadal, J; Pérez, J; Plaza, A | 1 |
| Borchgrevink, P; Dale, O; Fredheim, O; Hamunen, K; Mellbye, A; Svendsen, K | 1 |
| Ista, E; Tibboel, D; Wildschut, E | 1 |
| Kutner, JS; Linnebur, SA; O'Bryant, CL; Yamashita, TE | 1 |
| Ewan, EE; Martin, TJ | 1 |
| da Silva, PS; Passos, RM; Waisberg, DR | 1 |
| Patel, TA; Rastogi, R; Swarm, RA | 1 |
| Cavalcanti, AB; Pfuetzenreiter, F; Poli-de-Figueiredo, LF; Wanzuita, R; Westphal, GA | 1 |
| Al-Qadheeb, NS; Devlin, JW; Garpestad, E; Griffin, R; Roberts, RJ; Ruthazer, R | 1 |
| Häkkinen, M; Launiainen, T; Ojanperä, I; Vuori, E | 1 |
| Banks, ML; Lunzer, MM; Negus, SS; Portoghese, PS; Rice, KC; Yekkirala, AS | 1 |
| Binst, D; Coppieters, E; Polis, I; Verbiest, T; Waelbers, T | 1 |
| Mitchell, C; Paech, MJ; Pavy, T; Russell, T | 1 |
| Bernardi, CA; Cassu, RN; Diniz, MS; Kanashiro, GP; Nicácio, GM | 1 |
| Derry, S; Hadley, G; Moore, RA; Wiffen, PJ | 1 |
| Carlson, DR; Kopecky, EA; Nalamachu, S; Pergolizzi, JV; Raffa, RB; Taylor, R; Varanasi, RK | 1 |
| Ashmawi, HA; Cascudo, GM; de Santana Neto, J; Guimaraes, GM; Neto, JO; Sousa, AM | 1 |
| Aoki, Y; Mizoguchi, H; Sakurada, S; Sakurada, T; Watanabe, C | 1 |
| Bruera, E; Didwaniya, N; Gottumukkala, RS; Reddy, A | 1 |
| Ahmedzai, SH; Boland, JW; Foulds, GA; Pockley, AG | 1 |
| Katsouri, L; Nutt, DJ; Parker, CA; Quelch, DR; Tyacke, RJ | 1 |
| Gala, G; Hillman, AD; Sultan, SM; Witenko, CJ | 1 |
| Avram, MJ; Greenberg, SB; Gupta, DK; Marymont, JH; Murphy, GS; Parikh, KN; Patel, SS; Shear, T; Szokol, JW | 1 |
| Atkinson, TJ; Fudin, J; Gala, G; Hillman, A; Pham, TC; Sultan, S; Witenko, C | 1 |
| Cederholm, SK; Durieux, ME; Fernández, L; Kazemi, A; McMurry, TL; Naik, BI; Nemergut, EC | 1 |
| Chung, CP; Hall, K; Murray, KT; Ray, WA; Stein, CM | 1 |
| Arima, T; Doi, S; Mori, T; Narita, M; Suzuki, T; Takahashi, T; Uchida, M; Uezono, Y; Uzawa, N; Yawata, A | 1 |
| Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE | 1 |
| Geurts, JW; Haumann, J; Joosten, EA; Kremer, B; van den Beuken-van Everdingen, MH; van Kuijk, SM | 2 |
| ElSohly, MA; Godfrey, M; Gul, SW; Gul, W; Stamper, B | 1 |
| Kaye, AD; Luo, JJ; Ruan, X | 1 |
| de Carvalho, AQ; DeRossi, R; Hermeto, LC; Macedo, GG; Pagliosa, RC | 1 |
| Arfken, CL; Greenwald, MK; Suchanek, J | 1 |
| Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB | 1 |
| Adami, C; Fernandez-Parra, R; Fontaine, C; Zilberstein, L | 1 |
| Donnadieu-Rigole, H; Eiden, C; Marrot, C; Mathieu, O; Peyrière, H | 1 |
| Fox, LM; Hoffman, RS; Manini, AF; Vlahov, D | 1 |
| Bell, RF; Derry, S; Moore, RA; Wee, B; Wiffen, PJ | 1 |
| Geurts, JW; Haumann, J; Hoebers, FJP; Joosten, EA; Kremer, B; van den Beuken-van Everdingen, MHJ; van Kuijk, SMJ | 1 |
| Amengual, M; Leigh, H; Rioja, E | 1 |
| Alexander-Scott, N; Boss, R; Brinkley-Rubinstein, L; Clarke, J; Green, TC; Marshall, BDL; Rich, JD | 1 |
| Brockbals, L; Ebert, LC; Gascho, D; Kraemer, T; Staeheli, SN; Steuer, AE | 1 |
| Brooke Lerner, E; Fumo, N; Peterson, BL; Schreiber, S | 1 |
| Blood, J; Brunt, LM; Deych, E; Kharasch, ED; Komen, H | 1 |
| Greevy, RA; Griffin, MR; Grijalva, CG; Mitchel, EF; Schaffner, W; Stein, CM; Wiese, AD | 1 |
| Carroll, JJ; Green, TC; Rich, JD; Stone, AC | 2 |
| Ammar, D; Baron, L; Chvetzoff, G; Collin, E; Delorme, C; Delorme, T; Faure, S; Filbet, M; Hubault, P; Jovenin, N; Krakowski, I; Magnet, M; Michenot, N; Minello, C; Poulain, P; Rostaing, S | 1 |
| Azar, P; Miles, I; Nikoo, M | 1 |
| Davies, TH; Hansen, Z; Loudin, S; Murray, S; Nellhaus, EM | 1 |
| Bellini, L; De Benedictis, GM | 1 |
| Heller, NM; Maher, DP; Walia, D | 1 |
| Moerke, MJ; Negus, SS | 1 |
| Futamura, A; Nakagawa, T; Suga, Y; Sugawara, H; Suzuki, S; Takase, H; Torigoe, K; Uchida, M; Uesawa, Y | 1 |
| Caffaro, MM; Fennell, TR; Mortensen, NP; Snyder, RW; Yueh, YL | 1 |
| Aguirre, J; Bastian, K; Buehler, PK; Hollinger, A; Lecheler, L; Rüst, CA; Siegemund, M; Slizyte, D; Studer, W; Toft, K | 1 |
| Gryczynski, J; Hill, P; Mitchell, SG; Nichols, H; Schwartz, RP; Wireman, K | 1 |
| Degenhardt, L; Gisev, N; Hall, WD; Roxburgh, A | 1 |
| Andersson, L; Håkansson, A; Johnson, B; Krantz, P | 1 |
| Dart, RC; Green, JL; Olsen, H; Severtson, G; Wang, GS | 1 |
| Bach, P; Brar, R; Dong, H; Fairbairn, N; Murphy, SM; Socias, ME; Wood, E | 1 |
| Alievi, MM; Boos, MZ; Gutierrez, LG; Herrera, JR; Mombach, VS; Monteiro, ER; Santos, EA | 1 |
| Homayra, F; Irvine, M; McGowan, G; Min, JE; Nosyk, B; Pearce, LA; Piske, M; Slaunwhite, A; Zhou, H | 1 |
| Ames, WA; Barnett, AM; Fuller, M; Homi, HM; Jooste, EH; Koo, J; Machovec, KA; Turi, JL | 1 |
| Grönbladh, A; Hallberg, M; Nyberg, F; Nylander, E; Zelleroth, S | 1 |
| Havig, SM; Rogde, S; Thaulow, CH; Vindenes, V; Øiestad, ÅML | 1 |
| Matsuda, Y; Niki, K; Okamoto, Y; Omae, T; Takagi, T; Takemura, M; Ueda, M | 1 |
| Laks, J; Peterkin, A; Weinstein, ZM | 1 |
| Nault, KM; Song, P; Wang, DJ | 1 |
| Al-Uzri, A; Atz, AM; Carreño, FO; Delmore, P; Edginton, AN; Ford, JL; Gerhart, JG; Gonzalez, D; Muller, WJ; Perrin, EM; Watt, KM | 1 |
| Droege, CA; Elson, NC; Goodman, MD; Hayes, HV; Nomellini, V; Pritts, TA; Salvator, A; Singer, KE; Wallen, TE | 1 |
| Coulter, C; Garnier, M; Moore, C | 1 |
| King, M; Olfson, M; Pancini, V; Schoenbaum, M; Waidmann, T | 1 |
| Bozinoff, N; Bruneau, J; Choi, JC; Hassan, A; Jutras-Aswad, D; Le Foll, B; Lim, R; Mok, WY; Rehm, J; Socias, ME; Wild, TC; Wood, E | 1 |
| Bodnar, AR; Jablonski, LA; Stewart, RW | 1 |
| Buresh, M; Nahvi, S; Steiger, S; Weinstein, ZM | 1 |
| Banks, ML; Blough, BE; Epstein, DH; Negus, SS; Shaham, Y; Townsend, EA | 1 |
| Fairman, BJ; Rezaeiahari, M | 1 |
| Díez-Pascual, AM; Kahrizi, M; Mirinejad, S; Mishra, S; Rahdar, A; Razlansari, M; Sargazi, S; Ulucan-Karnak, F | 1 |
| Drozdzynska, M; Vettorato, E; Viilmann, I | 1 |
| Bello, D; Luo, J; Pagsuyoin, S | 1 |
| Antonini, V; Breland, H; Dunn, J; Freese, T; Larkins, S; McGovern, M; Rawson, R | 1 |
| Berger, O; Bou Harfouch, LT; Buresh, ME; Patel, SM; Racha, S | 1 |
| Dawson, E; Gordon, AJ; Passik, S; Saloner, B; Stein, BD; Whitley, P | 1 |
| Case, P; Green, TC; Hughto, JMW; Moyo, P; Palacios, WR; Rapisarda, SS; Silcox, J; Stopka, TJ; Tapper, A | 1 |
| Ali, SA; Bedder, M; Harris, R; Shell, J | 1 |
| Bastos, FI; Bianchi, LM; Carvalho, RM; da Cunha, AJLA; de Magalhães-Barbosa, MC; Prata-Barbosa, A; Rodrigues-Santos, G | 1 |
23 review(s) available for methadone and fentanyl
| Article | Year |
|---|---|
Pediatric uses of opioids.
Topics: Child; Child, Preschool; Codeine; Drug Interactions; Fentanyl; Humans; Infant; Infant, Newborn; Meperidine; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Pediatrics; Receptors, Opioid | 1989 |
The pharmacologic management of pain in children.
Topics: Analgesia, Epidural; Analgesics; Child; Child, Preschool; Codeine; Fentanyl; Humans; Infant; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Pain | 1989 |
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors | 1986 |
[Analgesics. 32].
Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine | 1969 |
Drug therapy: analgetic drugs--the potent analgetics.
Topics: Analgesics; Blood Circulation; Fentanyl; Humans; Intestines; Levallorphan; Meperidine; Methadone; Methotrimeprazine; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Nausea; Pain; Pentazocine; Psychopharmacology; Respiration; Substance-Related Disorders; Urinary Tract; Vomiting | 1972 |
Recent advances in acute pain management.
Topics: Acute Disease; Administration, Oral; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Local; Child; Child, Preschool; Drug Combinations; Fentanyl; Humans; Infant; Lidocaine; Lidocaine, Prilocaine Drug Combination; Methadone; Pain; Pain Measurement; Prilocaine; Self Administration | 1995 |
[Treatment of pain in oncology].
Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Dissociative; Diphosphonates; Fentanyl; Humans; Ketamine; Methadone; Morphine; Neoplasms; Pain; Pamidronate; Suppositories; Tramadol | 1997 |
Screening for drugs of abuse (II): Cannabinoids, lysergic acid diethylamide, buprenorphine, methadone, barbiturates, benzodiazepines and other drugs.
Topics: Barbiturates; Benzodiazepines; Buprenorphine; Cannabinoids; Cyclizine; Dextropropoxyphene; Drug Combinations; Fentanyl; Humans; Ketamine; Lysergic Acid Diethylamide; Methadone; Pentazocine; Substance Abuse Detection | 1997 |
Opioid rotation for cancer pain: rationale and clinical aspects.
Topics: Analgesics, Opioid; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Narcotics; Neoplasms; Pain | 1999 |
Morphine is not the only analgesic in palliative care: literature review.
Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Ketamine; Methadone; Morphine; Neoplasms; Pain; Palliative Care | 2004 |
Cancer pain management in children.
Topics: Analgesics, Opioid; Anesthesia, Conduction; Child; Chronic Disease; Fentanyl; Humans; Injections, Spinal; Methadone; Neoplasms; Pain; Pain Measurement; Palliative Care | 2004 |
Interpretation of opioid levels: comparison of levels during chronic pain therapy to levels from forensic autopsies.
Topics: Analgesics, Opioid; Autopsy; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Pain, Intractable | 2005 |
Are one or two dangerous? Opioid exposure in toddlers.
Topics: Analgesics, Opioid; Child, Preschool; Codeine; Dose-Response Relationship, Drug; Drug Overdose; Emergency Medicine; Fentanyl; Humans; Infant; Methadone; Pediatrics; Poisoning; Tramadol | 2005 |
The management of pain in children with life-limiting illnesses.
Topics: Analgesics, Opioid; Child; Chronic Disease; Codeine; Fentanyl; Humans; Hydromorphone; Ketamine; Methadone; Morphine; Nociceptors; Oxycodone; Pain; Pain Measurement; Severity of Illness Index | 2007 |
Effectiveness of opioids in the treatment of chronic non-cancer pain.
Topics: Analgesics, Opioid; Drug Administration Schedule; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Oxymorphone; Pain; Quality of Life; Time Factors; Tramadol | 2008 |
Pediatric palliative care: use of opioids for the management of pain.
Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Child; Delayed-Action Preparations; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Narcotics; Pain; Palliative Care | 2009 |
Opioids in people with cancer-related pain.
Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Codeine; Fentanyl; Humans; Methadone; Neoplasms; Oxycodone; Pain | 2008 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Depressive Disorder; Desipramine; Drug Interactions; Duloxetine Hydrochloride; Fentanyl; Humans; Male; Methadone; Middle Aged; Oxycodone; Polypharmacy; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Sulfonamides; Thiophenes; Transdermal Patch | 2011 |
Transdermal fentanyl for cancer pain.
Topics: Administration, Cutaneous; Analgesics, Opioid; Fentanyl; Humans; Methadone; Morphine; Neoplasms; Pain; Pain Measurement; Randomized Controlled Trials as Topic | 2013 |
Opioids for cancer pain - an overview of Cochrane reviews.
Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Fentanyl; Humans; Hydromorphone; Methadone; Oxycodone; Phenols; Review Literature as Topic; Tapentadol; Tramadol | 2017 |
[Opioid switch and change of route of administration in cancer patients treated by morphine].
Topics: Administration, Oral; Analgesics, Opioid; Breakthrough Pain; Cancer Pain; Drug Substitution; Fentanyl; France; Humans; Hydromorphone; Injections, Intravenous; Injections, Subcutaneous; Methadone; Morphine; Oxycodone; Phenols; Tapentadol | 2018 |
Current Best Practices for Acute and Chronic Management of Patients with Opioid Use Disorder.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Comorbidity; Disease Management; Drug Overdose; Female; Fentanyl; Harm Reduction; Humans; Male; Mental Disorders; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Practice Guidelines as Topic; Prevalence | 2022 |
Nanobiosensors for detection of opioids: A review of latest advancements.
Topics: Analgesics, Opioid; Buprenorphine; Fentanyl; Gold; Illicit Drugs; Methadone; Oxycodone; Silver; Tramadol; Wastewater | 2022 |
26 trial(s) available for methadone and fentanyl
| Article | Year |
|---|---|
Comparison of four narcotic analgesics for extradural analgesia.
Topics: Adult; Aged; Analgesics, Opioid; Epidural Space; Female; Fentanyl; Hemodynamics; Humans; Injections; Male; Meperidine; Methadone; Middle Aged; Morphine; Pain, Postoperative; Respiration; Time Factors | 1982 |
[Comparative study of postoperative analgesia with methadone and fentanyl in continuous peridural perfusion].
Topics: Abdomen; Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Pain, Postoperative; Prospective Studies | 1997 |
Pitfalls of opioid rotation: substituting another opioid for methadone in patients with cancer pain.
Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Hydromorphone; Levorphanol; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Patient Satisfaction; Prospective Studies | 2002 |
Methadone for the induction of anesthesia: plasma histamine concentration, arterial blood pressure, and heart rate.
Topics: Adult; Aged; Analysis of Variance; Anesthesia; Blood Pressure; Double-Blind Method; Female; Fentanyl; Heart Rate; Histamine; Humans; Male; Methadone; Middle Aged | 2004 |
Mu-opioid self-administration vs passive administration in heroin abusers produces differential EEG activation.
Topics: Adult; Analgesics, Opioid; Double-Blind Method; Electroencephalography; Female; Fentanyl; Heroin Dependence; Humans; Male; Methadone; Naloxone; Narcotic Antagonists; Narcotics; Psychiatric Status Rating Scales; Pupil; Receptors, Opioid, mu; Self Administration | 2005 |
Opioid switching from transdermal fentanyl to oral methadone in patients with cancer pain.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Analgesics, Opioid; Drug Administration Schedule; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Neoplasms; Pain Measurement; Pain, Intractable; Palliative Care; Time Factors | 2004 |
Opioid craving and seeking behavior in physically dependent volunteers: effects of acute withdrawal and drug reinforcement opportunity.
Topics: Adult; Conditioning, Operant; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fentanyl; Heroin Dependence; Humans; Male; Methadone; Naloxone; Narcotic Antagonists; Narcotics; Psychiatric Status Rating Scales; Reinforcement, Psychology; Reward; Substance Withdrawal Syndrome; Surveys and Questionnaires | 2005 |
Rapid switching between transdermal fentanyl and methadone in cancer patients.
Topics: Administration, Cutaneous; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Neoplasms; Pain; Pain Measurement; Prospective Studies; Treatment Outcome | 2005 |
Sustained-release oral morphine versus transdermal fentanyl and oral methadone in cancer pain management.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Patient Satisfaction; Prospective Studies; Quality of Life; Treatment Outcome | 2008 |
The use of fentanyl buccal tablets as breakthrough medication in patients receiving chronic methadone therapy: an open label preliminary study.
Topics: Administration, Buccal; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Tolerance; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Neoplasms; Pain; Palliative Care; Prospective Studies; Severity of Illness Index; Tablets | 2011 |
A trial of methadone tapering schedules in pediatric intensive care unit patients exposed to prolonged sedative infusions.
Topics: Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Intensive Care Units, Pediatric; Male; Methadone; Midazolam; Prospective Studies; Substance Withdrawal Syndrome; United States | 2011 |
[Adjuvant methadone or fentanyl in spinal anesthesia with bupivacaine: a randomized, double-blind, placebo-controlled trial].
Topics: Adjuvants, Anesthesia; Aged; Analgesia; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Diazepam; Double-Blind Method; Drug Interactions; Female; Fentanyl; Humans; Hysterectomy, Vaginal; Methadone; Midazolam; Middle Aged; Pain, Postoperative; Preanesthetic Medication; Subarachnoid Space; Time Factors | 2010 |
Replacement of fentanyl infusion by enteral methadone decreases the weaning time from mechanical ventilation: a randomized controlled trial.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Anesthetics, Intravenous; Brazil; Double-Blind Method; Female; Fentanyl; Hospital Mortality; Humans; Intensive Care Units; Male; Methadone; Middle Aged; Pain Management; Prospective Studies; Treatment Outcome; Ventilator Weaning | 2012 |
Extradural anesthesia with lidocaine combined with fentanyl or methadone to ovariohisterectomy in dogs.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Animals; Blood Pressure; Dogs; Drug Combinations; Female; Fentanyl; Heart Rate; Hysterectomy; Lidocaine; Methadone; Ovariectomy; Reproducibility of Results; Respiratory Rate; Time Factors | 2013 |
Intraoperative Methadone for the Prevention of Postoperative Pain: A Randomized, Double-blinded Clinical Trial in Cardiac Surgical Patients.
Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cough; Double-Blind Method; Female; Fentanyl; Humans; Intraoperative Period; Male; Methadone; Middle Aged; Pain Measurement; Pain, Postoperative; Treatment Outcome | 2015 |
The Effect of Dexmedetomidine on Postoperative Opioid Consumption and Pain After Major Spine Surgery.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Back Pain; Chi-Square Distribution; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Early Termination of Clinical Trials; Female; Fentanyl; Humans; Hydromorphone; Lumbar Vertebrae; Male; Methadone; Middle Aged; Odds Ratio; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Prospective Studies; Thoracic Vertebrae; Time Factors; Treatment Outcome; Virginia | 2016 |
Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
Topics: Adult; Aged; Analgesics, Opioid; Cancer Pain; Female; Fentanyl; Head and Neck Neoplasms; Humans; Male; Methadone; Middle Aged; Neuralgia; Pain Measurement; Patient Satisfaction; Prospective Studies; Quality of Life | 2016 |
Fentanyl and methadone used as adjuncts to bupivacaine for lumbosacral epidural analgesia in sheep.
Topics: Adjuvants, Anesthesia; Analgesia, Epidural; Anesthetics, Local; Animals; Bupivacaine; Drug Combinations; Female; Fentanyl; Lumbosacral Region; Methadone; Sheep; Treatment Outcome | 2017 |
Comparison of intratesticular lidocaine, sacrococcygeal epidural lidocaine and intravenous methadone in cats undergoing castration: a prospective, randomized, investigator-blind clinical trial.
Topics: Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Animals; Cats; Dexmedetomidine; Fentanyl; Lidocaine; Male; Methadone; Orchiectomy; Pain, Postoperative; Pregnanediones; Prospective Studies; Sacrococcygeal Region; Testis | 2017 |
Methadone versus Fentanyl in Patients with Radiation-Induced Nociceptive Pain with Head and Neck Cancer: A Randomized Controlled Noninferiority Trial.
Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Head and Neck Neoplasms; Humans; Male; Methadone; Middle Aged; Nociceptive Pain; Pain Measurement; Radiation Injuries; Radiotherapy | 2018 |
Postoperative respiratory effects of intravenous fentanyl compared to intravenous methadone in dogs following spinal surgery.
Topics: Anesthesia, Intravenous; Animals; Dogs; Fentanyl; Infusions, Intravenous; Injections, Intravenous; Laminectomy; Lumbar Vertebrae; Methadone; Postoperative Period; Respiratory Physiological Phenomena; Thoracic Vertebrae | 2017 |
Intraoperative Methadone in Same-Day Ambulatory Surgery: A Randomized, Double-Blinded, Dose-Finding Pilot Study.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Fentanyl; Humans; Hydromorphone; Intraoperative Period; Male; Methadone; Middle Aged; Pain Management; Pain Measurement; Pain, Postoperative; Pilot Projects; Postoperative Period; Treatment Outcome | 2019 |
A preoperative single dose of methadone for moderate-to-severely painful surgery reduces postoperative morphine consumption.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia; Double-Blind Method; Female; Fentanyl; Humans; Length of Stay; Male; Methadone; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Preoperative Care | 2019 |
Slow release oral morphine versus methadone for opioid use disorder in the fentanyl era (pRESTO): Protocol for a non-inferiority randomized clinical trial.
Topics: Adult; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Overdose; Equivalence Trials as Topic; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Satisfaction; Quality of Life; Young Adult | 2020 |
Total intravenous anesthesia in domestic chicken (Gallus gallus domesticus) with propofol alone or in combination with methadone, nalbuphine or fentanyl for ulna osteotomy.
Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Chickens; Fentanyl; Methadone; Nalbuphine; Osteotomy; Propofol; Prospective Studies; Ulna | 2020 |
Impact of fentanyl use on initiation and discontinuation of methadone and buprenorphine/naloxone among people with prescription-type opioid use disorder: secondary analysis of a Canadian treatment trial.
Topics: Analgesics, Opioid; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Canada; Female; Fentanyl; Humans; Male; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Prescriptions | 2022 |
146 other study(ies) available for methadone and fentanyl
| Article | Year |
|---|---|
From hit to lead. Combining two complementary methods for focused library design. Application to mu opiate ligands.
Topics: Animals; Cerebral Cortex; Combinatorial Chemistry Techniques; Humans; Imidazoles; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Radioligand Assay; Rats; Receptors, Opioid, mu; Solubility; Spiro Compounds; Structure-Activity Relationship | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists.
Topics: Allosteric Regulation; Dextropropoxyphene; Fentanyl; Methadone; Models, Biological; Models, Molecular; Molecular Conformation; Morphine; Nalorphine; Naloxone; Narcotics; Pentazocine; Phenazocine; Protein Conformation; Receptors, Opioid; Structure-Activity Relationship | 1976 |
Interaction of narcotic analgesics with dopamine receptors in rat brain.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Corpus Striatum; Cyclic AMP; Depression, Chemical; Dextromoramide; Dextropropoxyphene; Dopamine; Enzyme Activation; Etorphine; Fentanyl; In Vitro Techniques; Male; Methadone; Rats; Receptors, Drug | 1975 |
Objective tests of analgesic drugs in ponies.
Topics: Analgesics; Animals; Disease Models, Animal; Female; Fentanyl; Horse Diseases; Horses; Male; Meperidine; Methadone; Oxymorphone; Pain; Pentazocine; Xylazine | 1979 |
Comparing the effects of anileridine, alphaprodine and fentanyl on schedule-controlled responding by pigeons.
Topics: Alphaprodine; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Fentanyl; Isonipecotic Acids; Male; Methadone; Morphine; Naloxone; Reinforcement Schedule | 1978 |
[Effect of analgesics on artificial bimolecular phospholipid membranes].
Topics: Analgesics; Dextromoramide; Dose-Response Relationship, Drug; Fentanyl; Membranes, Artificial; Methadone; Morphine; Phospholipids; Piperidines | 1975 |
Investigations on drug produced and subjectively experienced discriminative stimuli. 2. Loperamide, an antidiarrheal devoid of narcotic cue producing actions.
Topics: Administration, Oral; Animals; Antidiarrheals; Codeine; Conditioning, Operant; Diphenoxylate; Discrimination Learning; Dose-Response Relationship, Drug; Fentanyl; Humans; Methadone; Morphine; Narcotics; Rats; Substance-Related Disorders; Time Factors | 1975 |
Epidural sufentanil for acute pain control in a patient with extreme opioid dependency.
Topics: Adult; Analgesia, Epidural; Analgesics; Female; Fentanyl; Humans; Methadone; Pain, Postoperative; Postoperative Complications; Substance Withdrawal Syndrome; Sufentanil | 1992 |
Differential cross-tolerance to mu and kappa opioid agonists in morphine-tolerant rats responding under a schedule of food presentation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Ethylketocyclazocine; Fentanyl; Food; Male; Methadone; Morphine; Naloxone; Narcotics; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule | 1991 |
Discriminative stimulus properties of U50,488 and morphine: effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Methadone; Morphine; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1990 |
Assessment of relative intrinsic activity of mu-opioid analgesics in vivo by using beta-funaltrexamine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Fentanyl; Levorphanol; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Time Factors | 1990 |
Sublingual absorption of selected opioid analgesics.
Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Analysis of Variance; Biological Availability; Buprenorphine; Fentanyl; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Mouth; Naloxone; Oxycodone; Time Factors | 1988 |
Antiaversive properties of opioids in the conditioned taste aversion test in the rat.
Topics: Animals; Avoidance Learning; Conditioning, Classical; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Fentanyl; Male; Methadone; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Taste | 1987 |
Antagonism of the analgesic effects of mu and kappa opioid agonists in the squirrel monkey.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Azocines; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Male; Methadone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri | 1988 |
High dose of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: clinical and theoretic implications.
Topics: Anesthesia, Spinal; Animals; Blood Pressure; Cats; Drug Tolerance; Fentanyl; Hyperesthesia; Methadone; Morphine; Morphine Derivatives; Naltrexone; Rats; Receptors, Drug; Stimulation, Chemical; Strychnine; Sufentanil; Sulfates; Touch | 1986 |
Use of beta-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Biological Assay; Buprenorphine; Butorphanol; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Etorphine; Fentanyl; Methadone; Mice; Morphine; Muscle Contraction; Nalbuphine; Nalorphine; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, mu | 1987 |
Comparison of the discriminative stimulus properties of U50,488 and morphine in pigeons.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Columbidae; Cyclazocine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Fentanyl; Methadone; Morphine; Naloxone; Phenazocine; Phencyclidine; Pyrrolidines; Time Factors | 1987 |
Contribution of 'receptor' affinity to analgesic potency.
Topics: 1-Propanol; Analgesics; Animals; Binding, Competitive; Brain; Cyclopropanes; Fentanyl; Guinea Pigs; Hydromorphone; In Vitro Techniques; Injections, Intravenous; Levorphanol; Meperidine; Methadone; Morphinans; Morphine; Pentanols; Receptors, Drug | 1974 |
[Permeation of active morphine-like substances at their sites of antinociceptive action in the brain as a function of their lipid-solubility following intravenous and intraventricular application].
Topics: Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Dental Pulp Test; Fentanyl; Hydromorphone; Ketones; Kinetics; Levorphanol; Lipids; Methadone; Morphinans; Morphine; Piperidines; Rabbits; Solubility; Tritium | 1970 |
Effects of narcotic analgesics and their antagonists on the rabbit isolated heart and its adrenergic nerves.
Topics: Animals; Autonomic Nervous System; Drug Interactions; Electric Stimulation; Female; Fentanyl; Heart; Heart Rate; In Vitro Techniques; Levallorphan; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Perfusion; Rabbits; Secretory Rate; Sympathetic Nervous System | 1973 |
Studies of drugs given before anaesthesia. XIX. The opiates.
Topics: Analgesics; Diazepam; Female; Fentanyl; Heroin; Humans; Levorphanol; Male; Meperidine; Methadone; Morphine; Papaverine; Phenazocine; Preanesthetic Medication; Vomiting | 1970 |
[On characterization of the bradykinin effect on smooth muscle].
Topics: Animals; Bradykinin; Bronchi; Codeine; Fentanyl; Guinea Pigs; Ileum; Levallorphan; Methadone; Morphine; Muscle, Smooth; Nalorphine; Piperidines; Thebaine | 1968 |
The antidiuretic effect of narcotic analgesics in the mouse.
Topics: Animals; Biological Assay; Diuresis; Drug Antagonism; Fentanyl; Levorphanol; Methadone; Mice; Morphine; Nalorphine; Water | 1968 |
Comparative cardiac contractile actions of six narcotic analgesics: morphine, meperidine, pentazocine, fentanyl, methadone and l-alpha-acetylmethadol (LAAM).
Topics: Analgesics, Opioid; Animals; Cats; Depression, Chemical; Drug Interactions; Fentanyl; Meperidine; Methadone; Methadyl Acetate; Morphine; Myocardial Contraction; Naloxone; Pentazocine; Stimulation, Chemical | 1980 |
Inhibition of ganglionic transmission by narcotic analgesics; an effect antagonized by naloxone, nalorphine and calcium.
Topics: Analgesics, Opioid; Animals; Calcium; Fentanyl; Ganglia, Sympathetic; Methadone; Morphine Derivatives; Nalorphine; Naloxone; Neural Inhibition; Oxycodone; Rana esculenta; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors | 1981 |
Strong analgesics in severe pain.
Topics: Analgesics, Opioid; Chronic Disease; Cocaine; Fentanyl; Half-Life; Heroin; Humans; Injections, Intramuscular; Methadone; Morphine; Pain, Intractable; Pain, Postoperative | 1984 |
Should regional anesthesia and pharmacological agents such as beta blockers and opiates be utilized in modulating pain response?
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alfentanil; Analgesia; Analgesics; Anesthesia, Conduction; Animals; Burns; Cyclooxygenase Inhibitors; Fentanyl; Half-Life; Humans; Methadone; Models, Chemical; Morphine; Narcotics; Nerve Block; Pain; Pain Management; Propranolol | 1984 |
Opiates and thermoregulation in mice. I. Agonists.
Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone | 1980 |
Relationship of duration of analgesia to opioid pharmacokinetic variables.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Fentanyl; Half-Life; Male; Metabolic Clearance Rate; Methadone; Morphine; Narcotics; Nociceptors; Rats; Receptors, Opioid | 1983 |
A novel form of dependency of hepatic extraction ratio of opioids in vivo upon the portal vein concentration of drug: comparison of morphine, diamorphine, fentanyl, methadone and buprenorphine in the chronically cannulated cow.
Topics: Animals; Buprenorphine; Cattle; Female; Fentanyl; Heroin; Kinetics; Liver; Liver Circulation; Methadone; Morphinans; Morphine; Narcotics | 1984 |
Opioid and nonopioid behavioral effects of methadone isomers.
Topics: Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Drug Tolerance; Fentanyl; Kinetics; Male; Methadone; Naloxone; Pentobarbital; Stereoisomerism | 1982 |
The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Epidural Space; Female; Fentanyl; Lipids; Male; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Nociceptors; Pain; Reflex; Skin; Time Factors | 1982 |
Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit.
Topics: Child; Female; Fentanyl; Humans; Iatrogenic Disease; Infant; Lorazepam; Male; Methadone; Midazolam; Phenobarbital; Substance Withdrawal Syndrome; Substance-Related Disorders | 1994 |
Kappa antinociceptive activity of spiradoline in the cold-water tail-flick assay in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Cold Temperature; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Male; Methadone; Naloxone; Narcotic Antagonists; Pain Measurement; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa; Stereoisomerism | 1998 |
Apparent thermodynamic parameters of ligand binding to the cloned rat mu-opioid receptor.
Topics: Analgesics; Animals; Binding, Competitive; CHO Cells; Cricetinae; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Ligands; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Pentazocine; Peptide Fragments; Peptides; Radioligand Assay; Rats; Receptors, Opioid, mu; Somatostatin; Sufentanil; Thermodynamics; Time Factors | 1998 |
The mu opioid irreversible antagonist beta-funaltrexamine differentiates the discriminative stimulus effects of opioids with high and low efficacy at the mu opioid receptor.
Topics: Animals; Buprenorphine; Butorphanol; Columbidae; Discrimination Learning; Female; Fentanyl; Levallorphan; Methadone; Morphine; Nalbuphine; Nalorphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu | 1998 |
Opioid substitution to reduce adverse effects in cancer pain management.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hospice Care; Humans; Male; Medical Audit; Methadone; Middle Aged; Morphine; Nausea; Neoplasms; Oxycodone; Pain; Pain Measurement; Prospective Studies; Sleep Stages; Sufentanil; Vomiting | 1999 |
Opioid consumption in Spain--the significance of a regulatory measure.
Topics: Analgesics, Opioid; Drug and Narcotic Control; Drug Utilization; Fentanyl; Humans; Meperidine; Methadone; Morphine; Regression Analysis; Spain; Tilidine | 1999 |
Discriminative stimulus effects of two doses of fentanyl in rats: pharmacological selectivity and effect of training dose on agonist and antagonist effects of mu opioids.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Fentanyl; Male; Methadone; Morphine; Nalbuphine; Nalorphine; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
[Opioids. Pharmacology, clinic, prospectives for an extensive use].
Topics: Analgesics, Opioid; Codeine; Drug Tolerance; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Oxycodone; Receptors, Opioid; Tramadol | 2000 |
Morphine and alternative opioids in cancer pain: the EAPC recommendations.
Topics: Administration, Oral; Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Administration Schedule; Fentanyl; Humans; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Injections, Subcutaneous; Methadone; Morphine; Neoplasms; Oxycodone; Pain; Palliative Care | 2001 |
Reversible delirium during opiod switching from transdermal fentanyl to methadone.
Topics: Administration, Cutaneous; Analgesics, Opioid; Delirium; Fentanyl; Humans; Male; Methadone; Middle Aged; Retreatment | 2001 |
Re: Reversible delirium during opioid switching.
Topics: Analgesics, Opioid; Delirium; Fentanyl; Humans; Methadone | 2001 |
Opioid therapy for chronic painful conditions.
Topics: Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Fentanyl; Humans; Karnofsky Performance Status; Low Back Pain; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Pain; Patient Selection; Practice Guidelines as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Time Factors | 2001 |
Intravenous methadone in the management of chronic cancer pain: safe and effective starting doses when substituting methadone for fentanyl.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Drug Administration Schedule; Female; Fentanyl; Humans; Infusions, Intravenous; Male; Methadone; Middle Aged; Neoplasms; Pain, Intractable; Palliative Care; Prospective Studies; Statistics, Nonparametric | 2001 |
Enteral methadone to expedite fentanyl discontinuation and prevent opioid abstinence syndrome in the PICU.
Topics: Adolescent; Analgesics, Opioid; Child; Fentanyl; Humans; Intensive Care Units, Pediatric; Methadone; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors | 2001 |
Discrimination of a single dose of morphine followed by naltrexone: substitution of other agonists for morphine and other antagonists for naltrexone in a rat model of acute dependence.
Topics: Acute Disease; Analgesics, Opioid; Animals; Disease Models, Animal; Fentanyl; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Use of irreversible antagonists to determine the relative efficacy of mu-opioids in a pigeon drug discrimination procedure: comparison of beta-funaltrexamine and clocinnamox.
Topics: Animals; Cinnamates; Columbidae; Female; Fentanyl; Methadone; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Narcotics; Reaction Time; Receptors, Opioid, mu; Sufentanil | 2003 |
Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice.
Topics: Animals; Area Under Curve; Behavior, Animal; Cell Membrane; Dose-Response Relationship, Drug; Drug Administration Schedule; Etorphine; Female; Fentanyl; Male; Methadone; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Narcotics; Pain Measurement; Posterior Horn Cells; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Time; Up-Regulation | 2003 |
Methadone dosage for prevention of opioid withdrawal in children.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Infant; Male; Methadone; Narcotics; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Substance Withdrawal Syndrome | 2003 |
Variable modulation of opioid brain uptake by P-glycoprotein in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzomorphans; Biological Transport; Brain; Drug Interactions; Fentanyl; Loperamide; Meperidine; Methadone; Mice; Narcotics; Quinidine; Time Factors; Verapamil | 2004 |
Withdrawal symptoms during chronic transdermal fentanyl administration managed with oral methadone.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Substance Withdrawal Syndrome | 2004 |
Outpatient management of sickle cell pain with chronic opioid pharmacotherapy.
Topics: Adult; Ambulatory Care; Analgesics, Opioid; Anemia, Sickle Cell; Female; Fentanyl; Humans; Male; Methadone; Oxycodone | 2004 |
"Opioid creep" is real and may be the cause of "fluid creep".
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Body Surface Area; Burns; Female; Fentanyl; Fluid Therapy; Humans; Hypnotics and Sedatives; Male; Meperidine; Methadone; Middle Aged; Morphine; Narcotics; Retrospective Studies | 2004 |
Morphine but not fentanyl and methadone affects mitochondrial membrane potential by inducing nitric oxide release in glioma cells.
Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Cell Line, Tumor; Electron Transport Complex IV; Fentanyl; Free Radicals; Glioma; Humans; Membrane Potentials; Methadone; Microscopy, Fluorescence; Mitochondria; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Signal Transduction; Spectrophotometry; Time Factors | 2004 |
Myocardial ischemia as a result of severe benzodiazepine and opioid withdrawal.
Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Benzodiazepines; Diazepam; Electrocardiography; Female; Fentanyl; Humans; Infant; Infant, Newborn; Infant, Premature; Methadone; Midazolam; Myocardial Ischemia; Neonatal Abstinence Syndrome; Treatment Outcome | 2005 |
Bradycardia during methadone therapy in an infant.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Bradycardia; Fentanyl; Humans; Infant; Male; Methadone; Substance Withdrawal Syndrome; Ventilator Weaning | 2006 |
Opiate pharmacology of intrathecal granulomas.
Topics: Analgesics, Opioid; Animals; Dogs; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Granuloma; Injections, Spinal; Male; Maximum Tolerated Dose; Methadone; Morphine; Spinal Cord | 2006 |
Equianalgesic dosing of opioids.
Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Fentanyl; Humans; Hydromorphone; Methadone; Pain; Therapeutic Equivalency | 2006 |
Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics.
Topics: Adenosine; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Heroin; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Male; Methadone; Morphine; Neuralgia; Pain; Rats; Rats, Inbred F344; Self Administration | 2007 |
Medicating "Margaret".
Topics: Advance Directives; Alzheimer Disease; Analgesics, Opioid; Antipsychotic Agents; Electroconvulsive Therapy; Female; Fentanyl; Hospice Care; Humans; Lorazepam; Methadone; Middle Aged; Morphine; Oxycodone; Pain; Palliative Care; Psychomotor Agitation; Right to Die | 2006 |
Opioid plasma concentrations during a switch from transdermal fentanyl to methadone.
Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Drug Administration Schedule; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Neoplasms; Pain Measurement; Pain, Intractable; Palliative Care; Time Factors; Treatment Outcome | 2007 |
Prescribing patterns and purchasing costs of long-acting opioids over nine years at an academic oncology hospital.
Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Costs; Drug Utilization; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Time Factors | 2007 |
Intrapartum and postpartum analgesia for women maintained on methadone during pregnancy.
Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Case-Control Studies; Cesarean Section; Female; Fentanyl; Humans; Labor Pain; Methadone; Pain Measurement; Pain Threshold; Pain, Postoperative; Postpartum Period; Pregnancy; Pregnancy Complications; Retrospective Studies; Substance-Related Disorders | 2007 |
When opioids cause pain.
Topics: Analgesics, Opioid; Back Pain; Carcinoma, Hepatocellular; Drug Therapy, Combination; Fentanyl; Humans; Hyperalgesia; Liver Neoplasms; Male; Methadone; Middle Aged; Oxycodone; Spinal Cord Compression | 2007 |
Behavioral economic analysis of drug preference using multiple choice procedure data.
Topics: Choice Behavior; Economics; Fentanyl; Fluoxetine; Hallucinogens; Humans; Hydromorphone; Injections, Intramuscular; Methadone; Models, Psychological; Motivation; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Narcotics; Psychotropic Drugs; Recreation; Selective Serotonin Reuptake Inhibitors; Substance Abuse, Intravenous; Substance-Related Disorders | 2008 |
Analysis of pain management drugs, specifically fentanyl, in hair: application to forensic specimens.
Topics: Analgesics, Opioid; Benzodiazepines; Carisoprodol; Dextropropoxyphene; Enzyme-Linked Immunosorbent Assay; Fentanyl; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Methadone; Oxycodone; Substance Abuse Detection; Tramadol | 2008 |
[Analgesics and palliative care].
Topics: Analgesics; Analgesics, Opioid; Fentanyl; Humans; Methadone; Morphine; Neoplasms; Pain; Palliative Care; Patient Care Team; Terminal Care | 2008 |
Clinical and diagnostic features of delayed hypoxic leukoencephalopathy.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Brain; Cocaine; Cognition Disorders; Depressive Disorder, Major; Drug Overdose; Female; Fentanyl; Fibromyalgia; Gait Disorders, Neurologic; Humans; Hypoxia, Brain; Magnetic Resonance Imaging; Methadone; Middle Aged; Motor Neurons; Narcotic Antagonists; Neuropsychological Tests; Psychoses, Substance-Induced; Suicide, Attempted | 2008 |
Frequency, indications, outcomes, and predictive factors of opioid switching in an acute palliative care unit.
Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Pain; Palliative Care; Prospective Studies; Treatment Outcome | 2009 |
Characteristics and comparative severity of respiratory response to toxic doses of fentanyl, methadone, morphine, and buprenorphine in rats.
Topics: Animals; Blood Gas Analysis; Buprenorphine; Catheterization; Fentanyl; Lactic Acid; Male; Methadone; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Narcotics; Plethysmography, Whole Body; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Respiratory Insufficiency; Respiratory Mechanics | 2009 |
Methadone-induced rigid-chest syndrome after substantial overdose.
Topics: Drug Administration Schedule; Drug Overdose; Fentanyl; Follow-Up Studies; Humans; Infant, Newborn; Infusions, Intravenous; Male; Medication Errors; Methadone; Muscle Rigidity; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Risk Assessment; Syndrome; Thoracic Wall | 2010 |
The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Arrestins; beta-Arrestins; Drug Tolerance; Fentanyl; Hot Temperature; Male; Methadone; Mice; Mice, Knockout; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Pain Threshold; Receptors, Opioid, mu | 2011 |
Sinus bradycardia related to methadone in a patient with myeloma receiving thalidomide therapy.
Topics: Analgesics, Opioid; Arrhythmia, Sinus; Fentanyl; Humans; Immunosuppressive Agents; Male; Methadone; Middle Aged; Multiple Myeloma; Spinal Injuries; Thalidomide | 2010 |
Choosing the unit of measurement counts: the use of oral morphine equivalents in studies of opioid consumption is a useful addition to defined daily doses.
Topics: Administration, Oral; Analgesics, Opioid; Cooperative Behavior; Databases, Factual; Drug Utilization; Fentanyl; Humans; Methadone; Morphine; Norway; Pain; Pain Measurement; Therapeutic Equivalency; World Health Organization | 2011 |
Creating or preventing opioid addiction, finding the right dose.
Topics: Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units, Pediatric; Male; Methadone; Midazolam; Substance Withdrawal Syndrome | 2011 |
Inconsistencies in opioid equianalgesic ratios: clinical and research implications.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Delayed-Action Preparations; Drug Dosage Calculations; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Randomized Controlled Trials as Topic | 2008 |
Rewarding electrical brain stimulation in rats after peripheral nerve injury: decreased facilitation by commonly abused prescription opioids.
Topics: Adenosine; Amines; Analgesics; Analgesics, Opioid; Animals; Brain; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hydromorphone; Injections, Spinal; Male; Methadone; Oxycodone; Peripheral Nerve Injuries; Rats; Rats, Inbred F344; Reward | 2011 |
Withdrawal treatment with clonidine after prolonged use of chloral hydrate in a pediatric intensive care patient.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Chloral Hydrate; Clonidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Intensive Care, Neonatal; Lorazepam; Male; Methadone; Midazolam; Pneumonia; Respiratory Insufficiency; Substance Withdrawal Syndrome | 2011 |
Impact of enteral methadone on the ability to wean off continuously infused opioids in critically ill, mechanically ventilated adults: a case-control study.
Topics: Adult; Aged; Analgesics, Opioid; Case-Control Studies; Critical Illness; Enteral Nutrition; Female; Fentanyl; Humans; Intensive Care Units; Male; Methadone; Middle Aged; Respiration, Artificial; Substance Withdrawal Syndrome | 2012 |
Comparison of fatal poisonings by prescription opioids.
Topics: Accidents; Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Central Nervous System Depressants; Codeine; Dextropropoxyphene; Drug Overdose; Ethanol; Fentanyl; Finland; Forensic Toxicology; Humans; Hypnotics and Sedatives; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Poisoning; Prescription Drug Misuse; Suicide; Tramadol; Young Adult | 2012 |
Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys.
Topics: Analgesics; Analgesics, Opioid; Animals; Calcium Signaling; Data Interpretation, Statistical; Female; Fentanyl; HEK293 Cells; Humans; Injections, Spinal; Macaca mulatta; Male; Methadone; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu | 2012 |
Perioperative changes in cardiac troponin I concentrations in dogs.
Topics: Anesthesia, General; Animals; Diazepam; Dogs; Female; Fentanyl; Infusions, Intravenous; Isoflurane; Male; Methadone; Perioperative Period; Propofol; Troponin I | 2013 |
Efficacy and safety of intraoperative intravenous methadone during general anaesthesia for caesarean delivery: a retrospective case-control study.
Topics: Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cesarean Section; Female; Fentanyl; Humans; Intraoperative Care; Methadone; Nausea; Pain Measurement; Pain, Postoperative; Pregnancy; Retrospective Studies; Treatment Outcome | 2013 |
Challenges of treating patients with chronic pain with dysphagia (CPD): physician and patient perspectives.
Topics: Analgesics, Opioid; Child; Chronic Pain; Data Collection; Deglutition Disorders; Fentanyl; Humans; Male; Medication Adherence; Methadone; Morphine; Palliative Care; Patient Medication Knowledge; Physicians; Treatment Outcome | 2014 |
Safety profile of intravenous patient-controlled analgesia for breakthrough pain in cancer patients: a case series study.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Breakthrough Pain; Constipation; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Nausea; Neoplasms; Pain Measurement; Retrospective Studies | 2014 |
Differential alternation of the antinociceptive effect of narcotic analgesics on the inflammatory pain state.
Topics: Animals; Fentanyl; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Methadone; Mice; Narcotics; Oxycodone; Pain; Pain Threshold; Physical Stimulation; Touch | 2014 |
What is your gut feeling about opioid rotation?
Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Biological Availability; Delayed-Action Preparations; Drug Administration Schedule; Fentanyl; Humans; Hydromorphone; Intestinal Obstruction; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Pain Management; Quality of Life | 2015 |
A preliminary evaluation of the effects of opioids on innate and adaptive human in vitro immune function.
Topics: Adaptive Immunity; Adult; Analgesics, Opioid; Buprenorphine; Codeine; Fentanyl; Humans; Immunity, Innate; Interleukin-2; Interleukin-6; Leukocytes, Mononuclear; Methadone; Monocytes; Morphine; Neutrophils; Oxycodone; Phagocytosis; Respiratory Burst; Tramadol | 2014 |
Imaging endogenous opioid peptide release with [11C]carfentanil and [3H]diprenorphine: influence of agonist-induced internalization.
Topics: Amphetamine; Analgesics, Opioid; Animals; Brain; Central Nervous System Stimulants; Diprenorphine; Fentanyl; Fluorescent Antibody Technique; Male; Methadone; Opioid Peptides; Positron-Emission Tomography; Radioligand Assay; Rats; Rats, Sprague-Dawley | 2014 |
Serotonin syndrome caused by fentanyl and methadone in a burn injury.
Topics: Adult; Analgesics, Opioid; Burns; Drug Interactions; Drug Therapy, Combination; Fentanyl; Humans; Male; Methadone; Serotonin Syndrome; Treatment Outcome; Voriconazole | 2015 |
Combined fentanyl and methadone induced serotonin syndrome is called into question.
Topics: Analgesics, Opioid; Burns; Fentanyl; Humans; Male; Methadone; Serotonin Syndrome | 2015 |
Prescription of Long-Acting Opioids and Mortality in Patients With Chronic Noncancer Pain.
Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Cardiovascular Diseases; Cause of Death; Chronic Pain; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Oxycodone; Propensity Score; Proportional Hazards Models; Retrospective Studies; Risk | 2016 |
Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist.
Topics: Animals; beta-Arrestins; CHO Cells; Cricetinae; Cricetulus; Dizocilpine Maleate; Endocytosis; Fentanyl; Gastrointestinal Transit; Male; Methadone; Mice, Inbred ICR; Nociception; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu | 2016 |
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine | 2016 |
LC-MS-MS Method for the Analysis of Miscellaneous Drugs in Wastewater During Football Games III.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Residues; Fentanyl; Football; Humans; Illicit Drugs; Limit of Detection; Meperidine; Methadone; Mississippi; Phencyclidine; Pyrrolidines; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater | 2016 |
Letter response: Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
Topics: Analgesics, Opioid; Fentanyl; Head and Neck Neoplasms; Humans; Methadone; Neuralgia; Pain; Pain Measurement | 2016 |
Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
Topics: Analgesics, Opioid; Fentanyl; Head and Neck Neoplasms; Humans; Methadone; Neoplasms; Neuralgia; Pain; Pain Measurement | 2016 |
Characterizing fentanyl use in methadone-maintained clients.
Topics: Female; Fentanyl; Heroin Dependence; Humans; Male; Methadone; Michigan; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Retrospective Studies; Substance Abuse Treatment Centers; Surveys and Questionnaires | 2017 |
A case of infant delirium in the neonatal intensive care unit.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acids; Delirium; Deprescriptions; Dexmedetomidine; Diazepam; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Methadone; Midazolam; Phenobarbital; Postoperative Complications; Pregnancy; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Risperidone | 2017 |
High opioids tolerance due to transmucosal fentanyl abuse.
Topics: Administration, Mucosal; Analgesics, Opioid; Drug Tolerance; Fentanyl; Humans; Male; Methadone; Middle Aged; Substance-Related Disorders | 2017 |
Risk factors for severe respiratory depression from prescription opioid overdose.
Topics: Adult; Age Factors; Analgesics, Opioid; Cohort Studies; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Humans; Intubation, Intratracheal; Male; Methadone; Middle Aged; Multivariate Analysis; Naloxone; Narcotic Antagonists; Odds Ratio; Oxycodone; Prescription Drug Misuse; Prospective Studies; Respiration, Artificial; Respiratory Insufficiency; Risk Factors; Severity of Illness Index; United States | 2018 |
Postincarceration Fatal Overdoses After Implementing Medications for Addiction Treatment in a Statewide Correctional System.
Topics: Adolescent; Adult; Buprenorphine; Cause of Death; Drug Overdose; Female; Fentanyl; Health Plan Implementation; Humans; Male; Methadone; Middle Aged; Naltrexone; Odds Ratio; Opioid-Related Disorders; Patient Discharge; Prisoners; Prisons; Retrospective Studies; Rhode Island; Transitional Care; Young Adult | 2018 |
Time-Dependent Postmortem Redistribution of Opioids in Blood and Alternative Matrices.
Topics: Analgesics, Opioid; Autopsy; Biotransformation; Chromatography, High Pressure Liquid; Fentanyl; Forensic Toxicology; Humans; Image-Guided Biopsy; Methadone; Opioid-Related Disorders; Postmortem Changes; Predictive Value of Tests; Pyrrolidines; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Tissue Distribution; Tomography, X-Ray Computed | 2018 |
Opioid Deaths in Milwaukee County, Wisconsin 2013-2017: The Primacy of Heroin and Fentanyl.
Topics: Analgesics, Opioid; Buprenorphine; Coroners and Medical Examiners; Fentanyl; Heroin; Humans; Hydrocodone; Illicit Drugs; Incidence; Methadone; Opioid-Related Disorders; Oxycodone; Substance-Related Disorders; Wisconsin | 2019 |
Long-acting Opioid Use and the Risk of Serious Infections: A Retrospective Cohort Study.
Topics: Adult; Aged; Analgesics, Opioid; Chronic Pain; Female; Fentanyl; Hospitalization; Humans; Immunosuppressive Agents; Infections; Male; Medicaid; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Retrospective Studies; Risk Factors; Tennessee; United States | 2019 |
Methadone maintenance treatment among patients exposed to illicit fentanyl in Rhode Island: Safety, dose, retention, and relapse at 6 months.
Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Overdose; Female; Fentanyl; Humans; Illicit Drugs; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Recurrence; Retrospective Studies; Rhode Island; Treatment Outcome | 2018 |
Methadone to buprenorphine/naloxone induction without withdrawal utilizing transdermal fentanyl bridge in an inpatient setting-Azar method.
Topics: Administration, Cutaneous; Analgesics, Opioid; Buprenorphine, Naloxone Drug Combination; Delayed-Action Preparations; Fentanyl; Humans; Inpatients; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome | 2018 |
Novel Withdrawal Symptoms of a Neonate Prenatally Exposed to a Fentanyl Analog.
Topics: Anticonvulsants; Clonidine; Female; Fentanyl; Humans; Infant, Newborn; Levetiracetam; Methadone; Myoclonus; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Parents; Pregnancy; Prenatal Exposure Delayed Effects; Treatment Outcome | 2019 |
Effect of three opioid-based analgesic protocols on the perioperative autonomic-mediated cardiovascular response in sheep.
Topics: Administration, Intravenous; Analgesia; Analgesics, Opioid; Animals; Arterial Pressure; Buprenorphine; Female; Fentanyl; Heart Rate; Methadone; Sheep, Domestic | 2019 |
Suppression of Human Natural Killer Cells by Different Classes of Opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Anesthesia; Buprenorphine; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Fluoresceins; Humans; Immunosuppression Therapy; K562 Cells; Killer Cells, Natural; Loperamide; Methadone; Morphinans; Morphine; Naloxone; Naltrexone; Succinimides; Toll-Like Receptor 4; Tramadol | 2019 |
Role of agonist efficacy in exposure-induced enhancement of mu opioid reward in rats.
Topics: Analgesics, Opioid; Animals; Buprenorphine; Dose-Response Relationship, Drug; Fentanyl; Male; Methadone; Morphine; Nalbuphine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Self Stimulation | 2019 |
Current Status of Adverse Events Related with Opioid Analgesics in Japan: Assessment Based on Japanese Adverse Drug Event Report Database.
Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Databases, Factual; Fentanyl; Humans; Japan; Methadone; Morphine; Oxycodone; Tapentadol | 2019 |
Placental trophoblast transfer of opioids following exposures to individual or mixtures of opioids
Topics: Analgesics, Opioid; Female; Fentanyl; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Maternal-Fetal Exchange; Methadone; Morphine; Naloxone; Oxycodone; Placenta; Pregnancy; Trophoblasts | 2019 |
Fentanyl exposure and preferences among individuals starting treatment for opioid use disorder.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Drug Overdose; Female; Fentanyl; Heroin; Humans; Male; Methadone; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Surveys and Questionnaires; Treatment Outcome | 2019 |
Characteristics and circumstances of heroin and pharmaceutical opioid overdose deaths: Comparison across opioids.
Topics: Adolescent; Adult; Analgesics, Opioid; Australia; Chronic Pain; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Naloxone; Opioid-Related Disorders; Tramadol; Young Adult | 2019 |
Investigating opioid-related fatalities in southern Sweden: contact with care-providing authorities and comparison of substances.
Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Female; Fentanyl; Heroin; Humans; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Registries; Retrospective Studies; Sweden | 2020 |
The impact of the prescription opioid epidemic on young children: Trends and mortality.
Topics: Analgesics, Opioid; Buprenorphine; Child, Preschool; Epidemics; Female; Fentanyl; Humans; Infant; Male; Methadone; Morphine; Opioid Epidemic; Oxycodone; Poison Control Centers; Prescription Drugs | 2020 |
Opioid agonist treatment and risk of mortality during opioid overdose public health emergency: population based retrospective cohort study.
Topics: Adolescent; Adult; British Columbia; Buprenorphine; Cause of Death; Cohort Studies; Emergencies; Female; Fentanyl; Humans; Illicit Drugs; Male; Methadone; Middle Aged; Mortality; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Public Health; Retrospective Studies; Risk Assessment; Young Adult | 2020 |
The effect of intraoperative methadone during pediatric cardiac surgery on postoperative opioid requirements.
Topics: Analgesics, Opioid; Cardiac Surgical Procedures; Child; Fentanyl; Humans; Infant, Newborn; Methadone; Pain, Postoperative | 2020 |
One year of methadone maintenance treatment in a fentanyl endemic area: Safety, repeated exposure, retention, and remission.
Topics: Analgesics, Opioid; Fentanyl; Follow-Up Studies; Humans; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Retrospective Studies; Rhode Island; United States | 2020 |
The effects of morphine, methadone, and fentanyl on mitochondria: A live cell imaging study.
Topics: Animals; Cell Line, Tumor; Fentanyl; Methadone; Mice; Mitochondria; Morphine; Narcotics; Rats; Time-Lapse Imaging | 2021 |
Methadone, Buprenorphine, Oxycodone, Fentanyl and Tramadol in Multiple Postmortem Matrices.
Topics: Analgesics, Opioid; Autopsy; Buprenorphine; Fentanyl; Methadone; Oxycodone; Tramadol | 2022 |
Tapentadol in Cancer Patients with Neuropathic Pain: A Comparison of Methadone, Oxycodone, Fentanyl, and Hydromorphone.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Hydromorphone; Japan; Male; Methadone; Middle Aged; Neoplasms; Neuralgia; Oxycodone; Pain Measurement; Retrospective Studies; Tapentadol | 2021 |
Impact of intraoperative methadone use on postoperative opioid requirements after cardiac surgery.
Topics: Analgesics, Opioid; Cardiac Surgical Procedures; Fentanyl; Humans; Methadone; Pain, Postoperative | 2022 |
Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity.
Topics: Adult; Analgesics, Opioid; Child; Fentanyl; Humans; Methadone; Obesity | 2022 |
Tracheostomy decreases continuous analgesia and sedation requirements.
Topics: Adult; Aged; Analgesia; Analgesics; Anti-Anxiety Agents; Endrin; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Methadone; Midazolam; Middle Aged; Morphine Derivatives; Pain; Propofol; Quetiapine Fumarate; Respiration, Artificial; Tracheostomy | 2022 |
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases.
Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem | 2022 |
Population-Based Opioid Prescribing and Overdose Deaths in the USA: an Observational Study.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Methadone; Practice Patterns, Physicians'; United States | 2023 |
Development of an intravenous low-dose buprenorphine initiation protocol.
Topics: Acute Pain; Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Retrospective Studies | 2022 |
Adapting methadone inductions to the fentanyl era.
Topics: Analgesics, Opioid; Fentanyl; Heroin; Humans; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; United States | 2022 |
Effect of TRV130 and methadone on fentanyl-vs.-food choice and somatic withdrawal signs in opioid-dependent and post-opioid-dependent rats.
Topics: Analgesics, Opioid; Animals; Buprenorphine; Fentanyl; Male; Methadone; Narcotics; Opioid-Related Disorders; Rats; Receptors, Opioid; Spiro Compounds; Substance Withdrawal Syndrome; Thiophenes | 2022 |
Impact of COVID-19 on the characteristics of opioid overdose deaths in Arkansas.
Topics: Analgesics, Opioid; Arkansas; COVID-19; Drug Overdose; Fentanyl; Humans; Methadone; Methamphetamine; Narcotics; Opiate Overdose; Pandemics; Substance-Related Disorders; Tramadol | 2022 |
Analgesic efficacy of a bilateral erector spinae plane block versus a fentanyl constant rate infusion in dogs undergoing hemilaminectomy: a retrospective cohort study.
Topics: Analgesics; Anesthetics; Animals; Dog Diseases; Dogs; Fentanyl; Methadone; Nerve Block; Pain, Postoperative; Retrospective Studies | 2022 |
Long-term wastewater-based surveillance and impacts of the COVID-19 pandemic on drug use trends in a U.S. Northeast rural town.
Topics: Amphetamine; Cocaine; COVID-19; Fentanyl; Humans; Hydrocodone; Methadone; N-Methyl-3,4-methylenedioxyamphetamine; Pandemics; Rural Population; Substance Abuse Detection; Substance-Related Disorders; Wastewater; Wastewater-Based Epidemiological Monitoring; Water Pollutants, Chemical | 2023 |
Stimulant use among patients in opioid treatment settings: Provider perspectives.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Humans; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders | 2023 |
Safety of rapid inpatient methadone initiation protocol: A retrospective cohort study.
Topics: Adult; Aftercare; Analgesics, Opioid; Cohort Studies; Drug Overdose; Fentanyl; Humans; Inpatients; Methadone; Patient Discharge; Retrospective Studies; United States | 2023 |
Polydrug use among patients on methadone medication treatment: Evidence from urine drug testing to inform patient safety.
Topics: Analgesics, Opioid; Chromatography, Liquid; Cocaine; Fentanyl; Heroin; Humans; Methadone; Methamphetamine; Opioid-Related Disorders; Patient Safety; Retrospective Studies; Tandem Mass Spectrometry; United States | 2023 |
Drug use patterns and factors related to the use and discontinuation of medications for opioid use disorder in the age of fentanyl: findings from a mixed-methods study of people who use drugs.
Topics: Analgesics, Opioid; Benzodiazepines; Buprenorphine; Crack Cocaine; Drug Overdose; Fentanyl; Heroin; Humans; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Pain; Pharmaceutical Preparations | 2023 |
Naloxone prescriptions among patients with a substance use disorder and a positive fentanyl urine drug screen presenting to the emergency department.
Topics: Analgesics, Opioid; Cocaine; Drug Overdose; Emergency Service, Hospital; Fentanyl; Humans; Illicit Drugs; Methadone; Naloxone; Opioid-Related Disorders; Prescriptions; Retrospective Studies | 2023 |
Shift in hospital opioid use during the COVID-19 pandemic in Brazil: a time-series analysis of one million prescriptions.
Topics: Adult; Analgesics, Opioid; Brazil; COVID-19; Fentanyl; Humans; Methadone; Morphine; Opioid-Related Disorders; Pandemics; Prescriptions; Remifentanil; Sufentanil; Tramadol | 2023 |