Compounds > methadone

methadone and dynorphins

methadone has been researched along with dynorphins in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carroll, FI; Che, T; Huang, XP; Jin, J; Karpiak, J; Kroeze, WK; Lansu, K; Liu, J; McCorvy, JD; Nagase, H; Roth, BL; Shoichet, BK1
Bart, G; Borg, L; Green, M; Ho, A; Kreek, MJ; Schluger, JH1
Goddard, B; Jacklin, D; Kreek, MJ; Leri, F; Levy, A; Zhou, Y1
Carmichael, B; Cummins, E; Kreek, MJ; Leri, F; Zhou, Y1
Babhadi-Ashar, N; Baharvand, P; Golab, F; Mohsenzadeh, A; Sadat-Shirazi, MS; Shahkarami, K; Shakeri, A; Vousooghi, N; Zarrindast, MR1

Trials

1 trial(s) available for methadone and dynorphins

ArticleYear
Suppressed prolactin response to dynorphin A1-13 in methadone-maintained versus control subjects.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2

    Topics: Adult; Dopamine; Dose-Response Relationship, Drug; Dynorphins; Female; Humans; Male; Methadone; Narcotics; Prolactin

2003

Other Studies

4 other study(ies) available for methadone and dynorphins

ArticleYear
In silico design of novel probes for the atypical opioid receptor MRGPRX2.
    Nature chemical biology, 2017, Volume: 13, Issue:5

    Topics: Calcium; Cell Degranulation; Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mast Cells; Molecular Docking Simulation; Molecular Probes; Molecular Structure; Nerve Tissue Proteins; Pyrazoles; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Structure-Activity Relationship

2017
Steady-state methadone blocks cocaine seeking and cocaine-induced gene expression alterations in the rat brain.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2009, Volume: 19, Issue:4

    Topics: Acoustic Stimulation; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Delivery Systems; Dynorphins; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Locomotion; Male; Methadone; Neuropeptides; Orexins; Photic Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Opioid, mu; RNA, Messenger

2009
Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:2

    Topics: Analgesics, Opioid; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Delivery Systems; Dynorphins; Gene Expression; Locomotion; Male; Methadone; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Opioid, mu; RNA, Messenger; Stereotyped Behavior

2012
Evaluation of dynorphin and kappa-opioid receptor level in the human blood lymphocytes and plasma: Possible role as a biomarker in severe opioid use disorder.
    Drug and alcohol dependence, 2019, 12-01, Volume: 205

    Topics: Adult; Animals; Biomarkers; Case-Control Studies; Dynorphins; Humans; Lymphocytes; Male; Methadone; Neurotransmitter Agents; Opiate Substitution Treatment; Opioid-Related Disorders; Protein Precursors; Receptors, Opioid, kappa; Young Adult

2019