methadone and doxepin

methadone has been researched along with doxepin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19908 (50.00)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
May, B; Prack, G; Rosenstock, J1
O'Brien, CP; Rickels, K; Woody, GE1
Spensley, J1
Cleary, J; Macenski, MJ; Thompson, T1
Dufficy, RG1
Bigelow, GE; Liebson, IA; McCaul, ME; Stitzer, ML1
Evans, BD; Marcovici, M; McLellan, AT; O'Brien, CP; Woody, GE1
Barranco, M; Kyle, EM; Seco, G; Titievsky, J1
Dietz, R; Haverkamp, W; Rademacher, S1
Cole, B; Fishbain, DA; Gao, J; Lewis, JE; Rosomoff, RS1

Reviews

1 review(s) available for methadone and doxepin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for methadone and doxepin

ArticleYear
Depression and anxiety in heroin addicts: a placebo-controlled study of doxepin in combination with methadone.
    The American journal of psychiatry, 1975, Volume: 132, Issue:4

    Topics: Administration, Oral; Adult; Alcoholic Intoxication; Amphetamine; Anxiety; Barbiturates; Capsules; Clinical Trials as Topic; Depression; Doxepin; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Patient Dropouts; Placebos; Psychiatric Status Rating Scales

1975
Doxepin as adjunctive therapy for depressed methadone maintenance patients: a double-blind study.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:11

    Topics: Adult; Depressive Disorder; Double-Blind Method; Doxepin; Drug Therapy, Combination; Female; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Placebos; Psychiatric Status Rating Scales

1982

Other Studies

13 other study(ies) available for methadone and doxepin

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Therapy of drug dependence in adolescents. Clinical aspects of somatic detoxification].
    Die Medizinische Welt, 1976, Dec-03, Volume: 27, Issue:49

    Topics: Adolescent; Adult; Age Factors; Doxepin; Female; Follow-Up Studies; Humans; Male; Methadone; Piracetam; Substance Withdrawal Syndrome; Substance-Related Disorders

1976
Doxepin: a useful adjunct in the treatment of heroin addicts in a methadone program.
    The International journal of the addictions, 1976, Volume: 11, Issue:1

    Topics: Adult; Aged; Anxiety; California; Doxepin; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Time Factors

1976
Effects on opioid-induced rate reductions by doxepin and bupropion.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:2

    Topics: Animals; Antidepressive Agents; Buprenorphine; Bupropion; Columbidae; Dose-Response Relationship, Drug; Doxepin; Drug Tolerance; Methadone; Propiophenones; Reaction Time; Reinforcement Schedule

1990
Use of psychotherapeutic drugs in the acute detoxification of heroin addicts.
    Military medicine, 1973, Volume: 138, Issue:11

    Topics: Adolescent; Adult; Aged; California; Doxepin; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Military Medicine; Time Factors; United States

1973
Outpatient methadone detoxification: effects of diazepam and doxepin as adjunct medications.
    NIDA research monograph, 1984, Volume: 55

    Topics: Adult; Diazepam; Doxepin; Humans; Methadone; Narcotics; Opioid-Related Disorders

1984
The use of antidepressants with methadone in depressed maintenance patients.
    Annals of the New York Academy of Sciences, 1982, Volume: 398

    Topics: Depressive Disorder; Doxepin; Female; Humans; Imipramine; Male; Methadone; Middle Aged; Opioid-Related Disorders

1982
QT prolongation and syncope with methadone, doxepin, and a beta-blocker.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Anxiety Disorders; Doxepin; Electrocardiography; Humans; Long QT Syndrome; Male; Methadone; Substance-Related Disorders; Syncope; Tachycardia

2005
Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report.
    Pain medicine (Malden, Mass.), 2009, Volume: 10, Issue:3

    Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Diazepam; Doxepin; Drug Overdose; Female; Heroin Dependence; Humans; Hydrocodone; Malpractice; Methadone; Nordazepam; Pain; Pain Measurement; Practice Guidelines as Topic; Shoulder; Shoulder Injuries; Temazepam

2009