methadone and deuterium

methadone has been researched along with deuterium in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (70.00)	18.7374
1990's	2 (20.00)	18.2507
2000's	1 (10.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Anggård, E; Gunne, LM; Holmstrand, J; Nilsson, MI	1
Jindal, SP; Lutz, T; Vestergaard, P	1
Hachey, DL; Kreek, MJ; Mattson, DH	1
Giles, HG; Hsia, JC; Leblanc, AE; Leung, CC; Marcus, H; Marshman, JA; Tam, JC	1
Bell, KH; Henkel, JG; Portoghese, PS	1
Hachey, DL; Irving, CS; Klein, PD; Kreek, MJ; Nakamura, K	1
Anggård, E; Holmstrand, J; Meresaar, U; Nilsson, MI	1
Foltz, RL; Gygi, SP; Nagasawa, PR; Rollins, DE; Wilkins, DG	1
Cooper, GA; Oliver, JS	1
Foster, DJ; Heinkele, G; Morton, EB; Mürdter, TE; Somogyi, AA	1

Trials

1 trial(s) available for methadone and deuterium

Article	Year
Stereoselective quantification of methadone and a d(6)-labeled isotopomer using high performance liquid chromatography-atmospheric pressure chemical ionization mass-spectrometry: application to a pharmacokinetic study in a methadone maintained subject. Therapeutic drug monitoring, 2006, Volume: 28, Issue:4 Topics: Administration, Oral; Adult; Area Under Curve; Atmospheric Pressure; Chromatography, High Pressure Liquid; Deuterium; Drug Administration Schedule; Half-Life; Humans; Injections, Intravenous; Isotope Labeling; Male; Metabolic Clearance Rate; Methadone; Molecular Structure; Narcotics; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Substance Withdrawal Syndrome; Tissue Distribution	2006

Article

Year

Stereoselective quantification of methadone and a d(6)-labeled isotopomer using high performance liquid chromatography-atmospheric pressure chemical ionization mass-spectrometry: application to a pharmacokinetic study in a methadone maintained subject.

Therapeutic drug monitoring, 2006, Volume: 28, Issue:4

Topics: Administration, Oral; Adult; Area Under Curve; Atmospheric Pressure; Chromatography, High Pressure Liquid; Deuterium; Drug Administration Schedule; Half-Life; Humans; Injections, Intravenous; Isotope Labeling; Male; Metabolic Clearance Rate; Methadone; Molecular Structure; Narcotics; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Substance Withdrawal Syndrome; Tissue Distribution

2006

Other Studies

9 other study(ies) available for methadone and deuterium

Article	Year
Pharmacokinetics of methadone during maintenance therapy: pulse labeling with deuterated methadone in the steady state. European journal of clinical pharmacology, 1979, Volume: 16, Issue:1 Topics: Administration, Oral; Adult; Deuterium; Female; Half-Life; Heroin Dependence; Humans; Injections, Intravenous; Isotope Labeling; Kinetics; Male; Methadone; Time Factors	1979
Mass fragmentographic determination of methadyl acetate in urine using stable isotope labeled analog as internal standard. Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:10 Topics: Animals; Deuterium; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Methadone; Methadyl Acetate; Rabbits	1978
Quantitative analysis of methadone in biological fluids using deuterium-labeled methadone and GLC-chemical-ionization mass spectrometry. Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:11 Topics: Adult; Chromatography, Gas; Deuterium; Humans; Isotope Labeling; Mass Spectrometry; Methadone; Methods; Stereoisomerism	1977
Markers for detection of supplementation in narcotic programs--deuterium-labeled methadone. Science (New York, N.Y.), 1976, Aug-06, Volume: 193, Issue:4252 Topics: Animals; Deuterium; Methadone; Rats; Structure-Activity Relationship	1976
Stereochemical studies on medicinal agents. 16. Conformational studies of methadone and isomethadone utilizing circular dichroism and proton magnetic resonance. Journal of medicinal chemistry, 1974, Volume: 17, Issue:1 Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Deuterium; Isomerism; Magnetic Resonance Spectroscopy; Methadone; Molecular Conformation; Stereoisomerism	1974
Quantitation of methadone enantiomers in humans using stable isotope-labeled [2H3]-, [2H5]-, and [2H8]Methadone. Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:1 Topics: Adult; Deuterium; Heroin Dependence; Humans; Isotope Labeling; Male; Mass Spectrometry; Methadone; Stereoisomerism	1982
Single dose pharmacokinetics and bioavailability of methadone in man studied with a stable isotope method. European journal of clinical pharmacology, 1981, Volume: 20, Issue:6 Topics: Administration, Oral; Adult; Biological Availability; Deuterium; Female; Half-Life; Humans; Injections, Intravenous; Kinetics; Male; Methadone	1981
Quantitative analysis of methadone and two major metabolites in hair by positive chemical ionization ion trap mass spectrometry. Journal of analytical toxicology, 1996, Volume: 20, Issue:6 Topics: Animals; Calibration; Deuterium; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Isotope Labeling; Male; Methadone; Narcotics; Pyrrolidines; Rats; Reference Standards; Sodium Hydroxide; Substance-Related Disorders	1996
Improved solid-phase extraction of methadone and its two major metabolites from whole blood. Journal of analytical toxicology, 1998, Volume: 22, Issue:5 Topics: Chemistry Techniques, Analytical; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Methadone; Narcotics; Pyrrolidines; Reference Standards	1998