methadone and codeine

methadone has been researched along with codeine in 225 studies

Research

Studies (225)

TimeframeStudies, this research(%)All Research%
pre-1990130 (57.78)18.7374
1990's18 (8.00)18.2507
2000's37 (16.44)29.6817
2010's31 (13.78)24.3611
2020's9 (4.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chang, TK; Ensom, MH; Kiang, TK1
Nagashima, R; Nishikawa, T; Tobita, M1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carroll, FI; Che, T; Huang, XP; Jin, J; Karpiak, J; Kroeze, WK; Lansu, K; Liu, J; McCorvy, JD; Nagase, H; Roth, BL; Shoichet, BK1
Halpern, LM2
Kaistha, KK; Tadrus, R1
Herndon, BL; Ringle, DA2
Barnett, A; Fiedler, E; Goldstein, J; Taber, R1
Di Gregorio, GJ; Knaiz, EK; Nagle, BT; Piraino, AJ1
Lawrence, F; Rappolt, RT1
DeAngelis, GG; McCaslin, FC; Ungerleider, JT1
Baeder, H; Herndon, BL; Paull, K; Ringle, DA1
Schuster, CR1
Judis, J2
Janda, R; Kaistha, KK; Tadrus, R1
Murgia, E; Walton, HF1
Dahlstrom, J; Medzihradsky, F1
Deacon, MA; Iorio, LC; Ryan, EA1
Colpaert, FC; Janssen, PA; Lal, H; Niemegeers, CJ1
Alexander, GJ1
Bochner, F; Eichelbaum, M; Mikus, G; Somogyi, AA1
Elias, H1
Koren, G; Maurice, L1
Deshpande, JK; Maxwell, LG; Yaster, M1
Carino, MA; Horita, A; Yamawaki, S1
Burke, CA; Posner, J1
Chesher, GB1
Neil, A; Terenius, L1
Sica, DA; Wolfert, AI1
Boone, DJ; Caudill, SP; Hansen, HJ1
Arraztoa, J; Hernández, A; Paredes, H; San Martín, S1
Bateman, DN; Blain, PG; Lane, RJ; Rawlins, MD1
Gorodetzky, CW1
Eddy, NB; May, EL1
Baden, MM; Huang, JC1
Terenius, L2
Bastos, ML; Jukofsky, D; Mulé, SJ1
Baettig, P; Bucher, K; Logara-Kalantzis, A1
Prianishnikova, NT; Raevskii, KS2
Cadden, JJ; Feigelson, EB1
Elliott, HW; Hine, CH; Nomof, N; Parker, KD1
Röthig, J1
Fujimoto, JM; Wang, RI1
Herz, A; Hess, R; Teschemacher, H; von Cube, B1
Leute, R1
Boura, AL; Haddlesey, DI; Harry, EJ; Lewis, JW; Mayor, PA1
Eddy, NB; Friebel, H; Hahn, KJ; Halbach, H1
Beattie, JM; Demetriou, JA; Lowe, ML; Weissman, N1
Hancock, BW1
Higgins, TN; Taylor, JD1
Marks, MJ; Medzihradsky, F1
Bourdon, P; Dugarin, J; Fournier, E; Gorceix, A; Piva, C1
Teiger, DG1
Sohn, D1
Mule, SJ1
DiMenza, S; Jaffe, JH; Renault, PR; Schuster, CR; Senay, EC; Smith, B1
DeBoer, L1
Stolman, A1
Frings, CS1
Frings, CS; Queen, CA1
Ciofalo, FR1
Sinclair, JG1
Pert, CB; Snyder, SH1
Kubasik, NP; Sine, HE; Woytash, J1
Kafer, ER1
Carmichael, FJ; Israel, Y1
Colasanti, B; Khazan, N1
Ahtee, L; Kääriäinen, I1
Bucher, UM1
Granat, FR; Saelens, JK1
Ghezzi, D; Mauron, C; Samanin, R; Valzelli, L1
Gorodetzky, CW; Kullberg, MP1
Aggarwal, V; Bath, R; Sunshine, I1
Burke, DH; Mann, DE1
Horwitz, CA; Jerome, E; Paulson, C; Ross, R; Stearns, J; Ward, PC1
Gould, JB; Rothstein, P1
Misra, AL1
Dundee, JW; Jones, PO1
Jaffe, JH; Schuster, CR; Smith, BB1
Baden, MM; Valanju, NN; Valanju, SN; Verma, SK1
Ho, IK; Loh, HH; Way, EL1
Alling, S; Kaplan, E; Mayron, LW1
Braun, L; Hyman, S; Oldendorf, SZ; Oldendorf, WH1
Goode, PG1
Jhamandas, K; Phillis, JW; Pinsky, C1
Ball, JC; Urbaitis, JC1
Mueller, GC; Noteboom, WD1
Kreppel, E1
Molinengo, L; Ricci-Gamalero, S1
Sulman, FG; Weller, CP1
Lorenzetti, OJ; Sancilio, LF1
Elliott, HW1
Bucher, K; Kade, F1
Tenen, SS1
Bauer, H; Konzett, H1
Blumberg, AG; Heaton, AM1
Sateia, MJ; Trzepacz, PT; Violette, EJ1
Neil, A1
Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE1
Miller, RR1
Baskerville, JC; Brands, B; Gowdey, CW; Hirst, M1
Feuer, E; French, J1
Bourne, DW; Haviland, AM; Schneider, JJ; Stephens, ID; Triggs, EJ1
Carter, FE; Chau, TT; Harris, LS1
Grasmeijer, G; Moolenaar, F; Visser, J1
Beauverie, P; Ghaleh, B; Jacquot, C; Khan, E; Poisson, N; van de Vyver, M1
Durand, H; Haas, C; Lowenstein, W1
Sonntag, I1
Baines, PR1
Fey, P; Moeller, MR; Wennig, R1
Strang, J; Unnithan, S1
Cutler, R; Fishbain, DA; Rosomoff, HL1
Brödemann, R; Krug, M; Matthies, R; Wagner, M1
Reiss, J1
Dettling, M; Tretter, F1
Alvarez Requejo, A; Caro-Patón, T; Carvajal, A; García del Pozo, J; Martín Arias, LH; Martín de Diego, I; Rueda, AM1
Ashford, M; Forrest, AR; Galloway, JH; Holden, M; Marsh, ID1
Degkwitz, P; Haasen, C; Krausz, M; Raschke, P; Verthein, U1
Djian, MC; Donnadieu, S1
Hirtl, C; Pfab, R; Zilker, T1
Bond, CM; Hickey, F; Matheson, C1
Lang, A; Ulmer, A; Weber, I; Zerdick, J1
Hensel, M; Kox, WJ1
Jussila, M; Porras, SP; Riekkola, ML; Sinervo, K1
Banbery, J; Raistrick, D; Wolff, K1
Arcuri, E; Centulio, F; Ciocca, F; D'Angiolino, G; Ginobbi, P; Marcelli, ME; Pelagalli, L; Tirelli, W1
Backmund, M; Eichenlaub, D; Meyer, K; Nagengast, O; Zwehl, W1
Janowska, E; Karakiewicz, B; Kozielec, T; Pach, J; Piekoszewski, W; Stanaszek, R; Winnik, L1
Casseday, S; Davoudzadeh, D; Huestis, MA; Preston, KL; Spanbauer, AC1
Backmund, M; Eichenlaub, D; Meyer, K; Schütz, CG; Soyka, M1
Gill, AC; Kennedy, I; Lewis, NL; Lui, K; Oei, J; Younan, N1
PATON, WD1
NERRETER, W1
RASCH, M1
GREEN, AF1
COLLIER, HO; SKERRY, R; WARNER, BT1
PARIS, J; U BOIS, R; VANDENDORP, F1
ADLER, TK; WAY, EL1
JOHNSON, CA; KING, RE1
COLLINS, RJ; MACGREGOR, DW; WEEKS, JR1
THOMPSON, WL; WALTON, RP1
BEIRN, SF; LAVELLE, S1
MEYERSTEIN, AN1
WANG, RI1
MASON, RM1
WEEKS, JR1
CHAPPEL, CI; VONSEEMANN, C1
HAMBURGER, E1
LASAGNA, L1
SHEMANO, I; WENDEL, H1
VESSMAN, J1
CLARK, JP1
COLLINS, RJ; WEEKS, JR1
ANDERSON, RC; EMMERSON, JL1
BRAEUNLICH, H1
ELLIOTT, HW; MILLER, JW1
Adams, CE; Oldham, NS; Sheard, L; Tompkins, CN; Wright, NM1
Böttiger, Y; Bulka, A; Kouya, PF; Svensson, JO; Wiesenfeld-Hallin, Z; Xu, XJ1
Davies, D; Desai, S; Malherbe, S; Tsui, BC1
Bart, G; Kreek, MJ; LaForge, KS; Lilly, C; Nielsen, DA1
Gregory, M; Stark, MM1
Sachdeva, DK; Stadnyk, JM1
Gerada, C; Hunt, C; Kerr, B; Pringle, M; Sheridan, J; Strang, J1
Blackburn-Munro, G; Erichsen, HK; Hao, JX; Xu, XJ1
Beijnen, JH; Hillebrand, MJ; Rook, EJ; Rosing, H; van Ree, JM1
Bermejo, AM; Fernández, P; Morales, L; Tabernero, MJ; Vázquez, C1
Backmund, M; Henkel, C; Meyer, K; Reimer, J; Schütz, CG; Soyka, M1
Haining, RL; Yu, AM1
Ashe, RG; Lowry, J; Mawhinney, S1
Bruce, M; McKenzie, JS; Raab, GM; Robertson, JR; Salter, A; Storkey, HR1
Hall, WD; Mattick, RP1
Bermejo, AM; Carro, AM; Fernández, P; Lago, M; Lorenzo, RA; Tabernero, MJ1
Friedrichsdorf, SJ; Kang, TI1
WATTS, DT1
Bond, BS1
Barnes, AJ; Brunet, BR; Huestis, MA; Mura, P; Scheidweiler, KB1
Lachenmeier, K; Lichtermann, D; Madea, B; Musshoff, F1
Quigley, C1
Barry, H; Cohen, DP; O'Connor, JJ; Unoh, E1
Elliot, DJ; Janchawee, B; Miners, JO; Raungrut, P; Somogyi, AA; Uchaipichat, V1
Cai, Z; Chen, G; Lai, Y; Li, Q; Lu, M; Qiu, B; Zhang, L1
Cone, EJ1
Christophersen, AS; Johansen, U; Oiestad, AM; Oiestad, EL1
Coller, JK; Gelston, EA; James, HM; Lopatko, OV; Schmidt, H; Somogyi, AA; White, JM1
Hendrickson, RG; McKeown, NJ1
Häkkinen, M; Launiainen, T; Ojanperä, I; Vuori, E1
Barbera, N; Busardò, FP; Indorato, F; Romano, G1
Cooley, J; Lopez-Avila, V; Thevis, M; Urdahl, R1
Moore, TM; Sabah, M; Tormey, WP1
Backmund, M; Beck, T; Haasen, C; Reimer, J; Ruckes, C; Schuler, C; Verthein, U; Walcher, S1
Ahmedzai, SH; Boland, JW; Foulds, GA; Pockley, AG1
Daldrup, T; Lerch, O; Temme, O1
Arbeláez, P; Borrull, F; Maria Marcé, R; Pocurull, E1
Black, DL; Caplan, YH; Cone, EJ; DePriest, A; Heltsley, R; Hild, C; Knight, J; Puet, BL; Robert, T1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
Conroy, S; Hill, D1
Degenhardt, L; Demirkol, A; Dunlop, A; Lintzeris, N; Muhleisen, P; Murnion, B; Nielsen, S1
Donnerstag, N; Lüthi, A; Mehlig, A; Raetz Bravo, A; Schneider, T; Taegtmeyer, A1
Bojko, B; Gómez-Ríos, GA; Pawliszyn, J; Reyes-Garcés, N1
Bruno, R; Hall, W; Lai, FY; Mueller, JF; O'Brien, J; Prichard, J; Thai, PK; van Dyken, E1
Finkelstein, Y; Gonzalez, A; Juurlink, DN; Macdonald, EM; Mamdani, MM; Sivilotti, MLA1
Bell, RF; Derry, S; Moore, RA; Wee, B; Wiffen, PJ1
Haymond, S; Heiman, H; Nagpal, G1
Lai, FY; Mueller, JF; O'Brien, J; Thai, P; Wilkins, C1
Baldacchino, A; Balfour, DJ; Matthews, K; Tolomeo, S1
Beck, O; Böttcher, M; Picht, F1
Beck, O; Böttcher, M; Keller, T; Lierheimer, S; Monticelli, FC1
Eidbo, SA; Hagedorn, JD; Kaufman, DE; Kropp Lopez, AK; Mathew, V; McCall, KL; Nichols, SD; Piper, BJ1
Coulter, C; Garnier, M; Moore, C1
Philip, J; Rubio, J; Somogyi, AA; Wong, AK1
Bateman, BT; Esposito, DB; Hernández-Díaz, S; Huybrechts, KF; Mogun, H; Straub, L; Werler, MM1
Asihaer, Y; Guan, MY; Hu, YF; Li, ML; Shu, MS; Zunong, J1
Buratti, E; Cerioni, A; Cingolani, M; Cippitelli, M; Froldi, R; Mietti, G; Scendoni, R2
Isbister, GK; Isoardi, KZ1

Reviews

23 review(s) available for methadone and codeine

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pediatric uses of opioids.
    Pediatric clinics of North America, 1989, Volume: 36, Issue:5

    Topics: Child; Child, Preschool; Codeine; Drug Interactions; Fentanyl; Humans; Infant; Infant, Newborn; Meperidine; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Pediatrics; Receptors, Opioid

1989
The pharmacologic management of pain in children.
    Comprehensive therapy, 1989, Volume: 15, Issue:10

    Topics: Analgesia, Epidural; Analgesics; Child; Child, Preschool; Codeine; Fentanyl; Humans; Infant; Meperidine; Methadone; Morphine; Naloxone; Narcotics; Pain

1989
Receptor mechanisms for nociception.
    International anesthesiology clinics, 1986,Summer, Volume: 24, Issue:2

    Topics: Analgesics, Opioid; Animals; Codeine; Drug Tolerance; Methadone; Morphine; Naloxone; Neurons, Afferent; Nociceptors; Opioid-Related Disorders; Receptors, Opioid; Spinal Cord

1986
[Analgesics. 32].
    Pharmazeutische Praxis, 1969, Volume: 5

    Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine

1969
Codeine and its alternates for pain and cough relief . 4. Potential alternates for cough relief.
    Bulletin of the World Health Organization, 1969, Volume: 40, Issue:5

    Topics: Alkaloids; Animals; Antitussive Agents; Cats; Codeine; Cough; Dogs; Guinea Pigs; Histamine H1 Antagonists; Humans; Isoquinolines; Meperidine; Methadone; Mice; Morphinans; Phenanthrenes; Phenothiazines; Rats; Substance-Related Disorders

1969
The opiates and their derivatives.
    Texas medicine, 1973, Volume: 69, Issue:6

    Topics: Codeine; Dose-Response Relationship, Drug; Drug Tolerance; Hallucinogens; Humans; Methadone; Morphine Dependence; Narcotics; Opium; Psychoses, Substance-Induced; Substance-Related Disorders

1973
The absorption, distribution, and excretion of drugs and poisons and their metabolites.
    Progress in chemical toxicology, 1974, Volume: 5

    Topics: Anesthetics; Anesthetics, Local; Animals; Cannabis; Codeine; Gases; Hallucinogens; Halothane; Humans; Hydrocarbons, Fluorinated; Lidocaine; Lysergic Acid Diethylamide; Mepivacaine; Mescaline; Methadone; Methoxyflurane; Narcotics; Pentazocine; Pharmaceutical Preparations; Poisons; Prilocaine; Solvents; Volatilization

1974
Drug screening.
    CRC critical reviews in clinical laboratory sciences, 1973, Volume: 4, Issue:4

    Topics: Amphetamine; Barbiturates; Bromides; Cocaine; Codeine; Drug Stability; Ethchlorvynol; Fluorometry; Glutethimide; Hemagglutination Inhibition Tests; Humans; Meprobamate; Methadone; Methods; Morphine; Pharmaceutical Preparations; Phenothiazines; Quinine; Salicylates

1973
[Do substitution treatments reduce the incidence of human immunodeficiency virus infections in intravenous heroin addicts? Review of pertinent literature].
    Annales de medecine interne, 1994, Volume: 145 Suppl 3

    Topics: Acquired Immunodeficiency Syndrome; Buprenorphine; Codeine; Female; Heroin Dependence; HIV Infections; HIV Seropositivity; HIV Seroprevalence; Humans; Incidence; Male; Methadone; Prospective Studies; Risk Factors; Self Medication; Sex Work; Sexual Behavior; Substance Abuse, Intravenous

1994
Opiate detoxification protocols. A clinical manual.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1993, Volume: 5, Issue:1

    Topics: Administration, Cutaneous; Clinical Protocols; Clonidine; Codeine; Female; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Psychiatric Status Rating Scales; Receptors, Opioid; Substance Withdrawal Syndrome

1993
DRUG ADDICTION: A REVIEW.
    The Journal of school health, 1964, Volume: 34

    Topics: Adolescent; Amphetamine; Amphetamines; Barbiturates; Cannabis; Codeine; Heroin; Humans; Hydromorphone; Jurisprudence; Meperidine; Mescaline; Methadone; Morphine Dependence; Nalorphine; Narcotic Antagonists; Psychotherapy; Statistics as Topic; Substance-Related Disorders

1964
ANTITUSSIVE DRUGS.
    Progress in medicinal chemistry, 1963, Volume: 19

    Topics: Antipsychotic Agents; Antitussive Agents; Chemistry, Pharmaceutical; Codeine; Cough; Dextromoramide; Drug Therapy; Humans; Meperidine; Methadone; Morphine; Pharmacology; Phenothiazines; Phenylacetates; Piperazines; Piperidines; Research; Thiophenes

1963
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS.
    Pharmacological reviews, 1964, Volume: 16

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Meperidine; Methadone; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Oxymorphone; Pentazocine; Phenazocine; Substance-Related Disorders; Toxicology

1964
ANALGESICS FOR USE IN DENTAL PRACTICE.
    Journal of oral therapeutics and pharmacology, 1965, Volume: 1

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Azepines; Codeine; Dentistry; Dextropropoxyphene; Drug Therapy; Meperidine; Methadone; Phenacetin

1965
Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments.
    Pharmacological reviews, 2005, Volume: 57, Issue:1

    Topics: Codeine; Genetics, Population; Haplotypes; Heroin Dependence; Humans; Male; Methadone; Molecular Biology; Opioid-Related Disorders; Pharmacogenetics; Receptors, Opioid

2005
Are one or two dangerous? Opioid exposure in toddlers.
    The Journal of emergency medicine, 2005, Volume: 29, Issue:1

    Topics: Analgesics, Opioid; Child, Preschool; Codeine; Dose-Response Relationship, Drug; Drug Overdose; Emergency Medicine; Fentanyl; Humans; Infant; Methadone; Pediatrics; Poisoning; Tramadol

2005
The management of pain in children with life-limiting illnesses.
    Pediatric clinics of North America, 2007, Volume: 54, Issue:5

    Topics: Analgesics, Opioid; Child; Chronic Disease; Codeine; Fentanyl; Humans; Hydromorphone; Ketamine; Methadone; Morphine; Nociceptors; Oxycodone; Pain; Pain Measurement; Severity of Illness Index

2007
Equianalgesia: applying evidence-based practice guidelines.
    Clinical journal of oncology nursing, 2008, Volume: 12, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Codeine; Drug Monitoring; Evidence-Based Medicine; Humans; Hydromorphone; Methadone; Morphine; Neoplasms; Nurse's Role; Nursing Assessment; Oncology Nursing; Pain; Practice Guidelines as Topic; Therapeutic Equivalency; Treatment Outcome

2008
Opioids in people with cancer-related pain.
    BMJ clinical evidence, 2008, Jul-31, Volume: 2008

    Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Codeine; Fentanyl; Humans; Methadone; Neoplasms; Oxycodone; Pain

2008
Opioids for cancer pain - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2017, 07-06, Volume: 7

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Fentanyl; Humans; Hydromorphone; Methadone; Oxycodone; Phenols; Review Literature as Topic; Tapentadol; Tramadol

2017
The Role of Pharmacogenomics in Opioid Prescribing.
    Current treatment options in oncology, 2022, Volume: 23, Issue:10

    Topics: Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2D6; Humans; Methadone; Oxycodone; Pharmacogenetics; Practice Patterns, Physicians'; Tramadol

2022

Trials

8 trial(s) available for methadone and codeine

ArticleYear
The effects of naloxone on opiate and placebo analgesia in healthy volunteers.
    Psychopharmacology, 1985, Volume: 87, Issue:4

    Topics: Adult; Analgesia; Analgesics, Opioid; Codeine; Endorphins; Female; Humans; Male; Methadone; Middle Aged; Naloxone; Pain; Pain Management; Placebos

1985
Methadyl acetate vs methadone. A double-blind study in heroin users.
    JAMA, 1972, Volume: 222, Issue:4

    Topics: Acetates; Administration, Oral; Adult; Amino Alcohols; Analysis of Variance; Benzene Derivatives; Clinical Trials as Topic; Codeine; Heroin; Humans; Illinois; Male; Methadone; Methylamines; Middle Aged; Placebos; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Work

1972
The prevention of analgesic-induced nausea and vomiting by cyclizine.
    The British journal of clinical practice, 1968, Volume: 22, Issue:9

    Topics: Analgesia; Clinical Trials as Topic; Codeine; Cyclizine; Female; Humans; Levorphanol; Male; Meperidine; Methadone; Nausea; Placebos; Vomiting

1968
Drug abuse in heroin users. An experimental study of self-administration of methadone, codeine, and pentazocine.
    Archives of general psychiatry, 1971, Volume: 24, Issue:4

    Topics: Administration, Oral; Clinical Trials as Topic; Codeine; Heroin; Humans; Methadone; Morphine Dependence; Pentazocine; Placebos; Self Medication; Substance-Related Disorders

1971
Opiate detoxification under anesthesia: no apparent benefit but suppression of thyroid hormones and risk of pulmonary and renal failure.
    Journal of toxicology. Clinical toxicology, 1999, Volume: 37, Issue:1

    Topics: Acute Kidney Injury; Adult; Anesthesia; Codeine; Female; Heroin Dependence; Humans; Male; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Respiratory Insufficiency; Substance Withdrawal Syndrome; Thyroid Hormones

1999
The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: an open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCT
    BMC family practice, 2004, Apr-29, Volume: 5

    Topics: Adolescent; Adult; Buprenorphine; Codeine; England; Follow-Up Studies; Health Services Research; Heroin Dependence; Humans; Methadone; Narcotic Antagonists; Opioid-Related Disorders; Primary Health Care; State Medicine; Substance Abuse Detection; Treatment Outcome

2004
Addressing the efficacy of dihydrocodeine versus methadone as an alternative maintenance treatment for opiate dependence: A randomized controlled trial.
    Addiction (Abingdon, England), 2006, Volume: 101, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Codeine; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Patient Compliance; Surveys and Questionnaires

2006
Maintenance treatment for opioid dependence with slow-release oral morphine: a randomized cross-over, non-inferiority study versus methadone.
    Addiction (Abingdon, England), 2014, Volume: 109, Issue:4

    Topics: Administration, Oral; Adult; Codeine; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Maintenance Chemotherapy; Male; Medication Adherence; Methadone; Middle Aged; Morphine; Morphine Derivatives; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Treatment Outcome

2014

Other Studies

194 other study(ies) available for methadone and codeine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In silico design of novel probes for the atypical opioid receptor MRGPRX2.
    Nature chemical biology, 2017, Volume: 13, Issue:5

    Topics: Calcium; Cell Degranulation; Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mast Cells; Molecular Docking Simulation; Molecular Probes; Molecular Structure; Nerve Tissue Proteins; Pyrazoles; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Structure-Activity Relationship

2017
Analgesic drugs in the management of pain.
    Archives of surgery (Chicago, Ill. : 1960), 1977, Volume: 112, Issue:7

    Topics: Analgesics; Anti-Anxiety Agents; Aspirin; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Hypnotics and Sedatives; Ibuprofen; Indomethacin; Methadone; Morphine; Oxycodone; Pain; Pain, Intractable; Pentazocine; Pyrazoles

1977
Thin-layer detection of pentazocine, tripelennamine, phencyclidine and propoxyphene alone or in combination with opiates in drug abuse urine screening programs.
    Journal of chromatography, 1978, Aug-01, Volume: 155, Issue:1

    Topics: Analgesics, Opioid; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonists; Humans; Methadone; Methods; Morphine; Pentazocine; Phencyclidine; Quinine; Substance-Related Disorders; Tripelennamine

1978
Immunologic effects of morphine administration in rabbits.
    Journal of immunology (Baltimore, Md. : 1950), 1975, Volume: 115, Issue:3

    Topics: Animals; Antibody Formation; Binding, Competitive; Carbon Radioisotopes; Carrier Proteins; Chemical Fractionation; Codeine; Cyclophosphamide; Drug Implants; Electrophoresis, Polyacrylamide Gel; Female; gamma-Globulins; Hemagglutination Tests; Hemocyanins; Heroin; Immunodiffusion; Levorphanol; Methadone; Morphine; Naloxone; Rabbits; Skin Tests

1975
Immunologic effects of morphine in rodents, rabbits, monkeys, and cats.
    Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie, 1976, Volume: 151, Issue:2

    Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Blood; Cats; Codeine; Cross Reactions; Female; Guinea Pigs; Haplorhini; Haptens; Hemagglutination Tests; Immunodiffusion; Methadone; Morphine; Rabbits; Rats; Stereoisomerism

1976
Etonitazine-induced rigidity and its antagonism by centrally acting muscle relaxants.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Analgesics, Opioid; Animals; Benzimidazoles; Benzyl Compounds; Catalepsy; Codeine; Cordotomy; Diethylamines; Fenclonine; Humans; Male; Methadone; Morphine; Muscle Relaxants, Central; Muscle Rigidity; Narcotic Antagonists; Rats; Time Factors

1975
Secretion of drugs by the parotid glands of rats and human beings.
    Journal of dental research, 1977, Volume: 56, Issue:5

    Topics: Acetylcholine; Adult; Amobarbital; Animals; Barbiturates; Chlorpromazine; Codeine; Glutethimide; Humans; Male; Meprobamate; Methadone; Morphine; Narcotics; Parotid Gland; Pentobarbital; Phenobarbital; Pilocarpine; Rats; Saliva; Secobarbital; Tranquilizing Agents

1977
Outpatient detoxification of heroin addiction, 1969--1973 (methadone, darvon, codeine, clonidine).
    Clinical toxicology, 1979, Volume: 14, Issue:1

    Topics: Clonidine; Codeine; Dextropropoxyphene; Heroin Dependence; Humans; Methadone

1979
Drug use and employment patterns before and during treatment.
    The International journal of the addictions, 1978, Volume: 13, Issue:8

    Topics: Amphetamines; Barbiturates; Codeine; Demography; Employment; Humans; Methadone; Morphine; Outcome and Process Assessment, Health Care; Substance-Related Disorders

1978
Comparison of immunogenicity of opiates bound to protein at different sites on the molecule: N-carboxy morphine-BSA.
    Pharmacological research communications, 1976, Volume: 8, Issue:3

    Topics: Animals; Antibody Specificity; Binding Sites; Carrier Proteins; Codeine; Haptens; Heroin; Immune Sera; Immunologic Techniques; Levorphanol; Methadone; Morphine; Morphine Derivatives; Naloxone; Protein Binding; Rabbits; Rats; Serum Albumin, Bovine; Structure-Activity Relationship

1976
Drugs as reinforcers in monkey and man.
    Pharmacological reviews, 1975, Volume: 27, Issue:4

    Topics: Animals; Codeine; Disease Models, Animal; Drug Therapy; Haplorhini; Heroin Dependence; Humans; Legislation, Drug; Methadone; Morphine; Pentazocine; Reinforcement Schedule; Reinforcement, Psychology; Substance-Related Disorders; United States

1975
Binding of codeine, morphine, and methadone to human serum proteins.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:6

    Topics: Binding, Competitive; Blood Proteins; Codeine; Dialysis; Humans; Methadone; Morphine; Protein Binding; Serum Albumin

1977
Simultaneous detection of a wide variety of commonly abused drugs in a urine screening program using thin-layer identification techniques.
    Journal of chromatography, 1975, Apr-16, Volume: 107, Issue:2

    Topics: 1-Propanol; Ammonia; Ammonium Chloride; Amphetamine; Barbiturates; Chloroform; Chromatography, Thin Layer; Codeine; Humans; Hypnotics and Sedatives; Indicators and Reagents; Ion Exchange Resins; Methadone; Methamphetamine; Methylphenidate; Morphine; Opium; Phenmetrazine; Substance-Related Disorders

1975
Ligand-exchange chromatography of alkaloids.
    Journal of chromatography, 1975, Feb-12, Volume: 104, Issue:2

    Topics: Alkaloids; Atropine; Chromatography, Ion Exchange; Cinchona; Cinchona Alkaloids; Cocaine; Codeine; Copper; Hydrolysis; Ion Exchange Resins; Methadone; Methods; Morphine; Noscapine; Papaverine; Plants, Medicinal; Quinine; Strychnine

1975
Concurrent determination of narcotic drugs in plasm by gas-liquid chromatography.
    Pharmacological research communications, 1975, Volume: 07, Issue:1

    Topics: Chromatography, Gas; Cocaine; Codeine; Cyclazocine; Humans; Levallorphan; Levorphanol; Methadone; Methods; Nalorphine; Naloxone; Narcotics; Pentazocine

1975
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1

    Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Injections, Intraperitoneal; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotics; Pentazocine; Substance Withdrawal Syndrome

1975
Investigations on drug produced and subjectively experienced discriminative stimuli. 2. Loperamide, an antidiarrheal devoid of narcotic cue producing actions.
    Life sciences, 1975, Mar-01, Volume: 16, Issue:5

    Topics: Administration, Oral; Animals; Antidiarrheals; Codeine; Conditioning, Operant; Diphenoxylate; Discrimination Learning; Dose-Response Relationship, Drug; Fentanyl; Humans; Methadone; Morphine; Narcotics; Rats; Substance-Related Disorders; Time Factors

1975
Direct use of ion-exchange papers in hemagglutination-inhibition tests for drug abuse.
    Clinical chemistry, 1976, Volume: 22, Issue:7

    Topics: Aspirin; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Paper; Codeine; Hemagglutination Inhibition Tests; Humans; Methadone; Morphine; Nicotine; Phenobarbital; Substance-Related Disorders

1976
Codeine O-demethylation: rat strain differences and the effects of inhibitors.
    Biochemical pharmacology, 1991, Mar-01, Volume: 41, Issue:5

    Topics: Animals; Codeine; Drug Interactions; Female; Kinetics; Methadone; Microsomes, Liver; Morphine; Oxidoreductases, O-Demethylating; Phenotype; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1991
[Substitute drug-assisted treatment of drug dependent patients in general practice].
    Fortschritte der Medizin, 1990, Apr-30, Volume: 108, Issue:13

    Topics: Ambulatory Care; Codeine; Combined Modality Therapy; Follow-Up Studies; Humans; Long-Term Care; Methadone; Opioid-Related Disorders

1990
Analeptic effect of opiate receptor agonists in rabbits.
    Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1

    Topics: Animals; Arousal; Brain; Central Nervous System Stimulants; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethylketocyclazocine; Etorphine; Male; Meperidine; Methadone; Morphine; Naltrexone; Narcotics; Phenazocine; Rabbits; Receptors, Opioid; Reflex

1985
The influence of analgesic drugs in road crashes.
    Accident; analysis and prevention, 1985, Volume: 17, Issue:4

    Topics: Accidents, Traffic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Automobile Driving; Codeine; Dextropropoxyphene; Drug Interactions; Drug Tolerance; Heroin; Humans; Methadone; Reaction Time

1985
Narcotic usage in renal failure.
    The International journal of artificial organs, 1988, Volume: 11, Issue:6

    Topics: Analgesics, Opioid; Codeine; Humans; Kidney Failure, Chronic; Methadone; Morphine

1988
Crisis in drug testing. Results of CDC blind study.
    JAMA, 1985, Apr-26, Volume: 253, Issue:16

    Topics: Amphetamines; Barbiturates; Centers for Disease Control and Prevention, U.S.; Cocaine; Codeine; Diagnostic Errors; Humans; Illicit Drugs; Laboratories; Methadone; Morphine; Pharmaceutical Preparations; Quality Control; Research Design; United States

1985
[3-step pharmacologic treatment of pain in cancer. Preliminary experience in Chile].
    Revista medica de Chile, 1988, Volume: 116, Issue:5

    Topics: Acetaminophen; Adult; Analgesics; Chile; Codeine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Pain Measurement

1988
Opiate-induced rhabdomyolysis.
    Human toxicology, 1985, Volume: 4, Issue:1

    Topics: Acute Kidney Injury; Adult; Aspartate Aminotransferases; Codeine; Creatine Kinase; Creatinine; Cyclizine; Drug Combinations; Female; Humans; Hypocalcemia; Male; Methadone; Middle Aged; Morphine; Myoglobin; Narcotics; Phosphates; Rhabdomyolysis; Suicide, Attempted

1985
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
The search for a better analgesic.
    Science (New York, N.Y.), 1973, Aug-03, Volume: 181, Issue:4098

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Heroin; Humans; Hydromorphone; Levorphanol; Meperidine; Methadone; Morphinans; Morphine Dependence; Structure-Activity Relationship

1973
Rapid methods of screening micro-quantities of abused drugs from urine samples for microcrystal tests.
    Clinical toxicology, 1973, Volume: 6, Issue:3

    Topics: Acids; Alkalies; Alkaloids; Chromatography, Thin Layer; Codeine; Crystallization; Crystallography; Heroin Dependence; Humans; Hydromorphone; Indicators and Reagents; Meperidine; Methadone; Methods; Morphine; Nicotine; Quinine; Substance-Related Disorders

1973
Stereospecific uptake of narcotic analgesics by a subcellular fraction of the guinea-pig ileum. A preliminary communication.
    Upsala journal of medical sciences, 1973, Volume: 78, Issue:3

    Topics: Analgesics; Animals; Codeine; Dextromoramide; Female; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Intestinal Absorption; Levorphanol; Male; Methadone; Morphine; Muscle, Smooth; Nalorphine; Naloxone; Narcotics; Subcellular Fractions; Tritium

1973
Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amphetamine; Apomorphine; Barbiturates; Chromatography, Thin Layer; Cocaine; Codeine; Cross Reactions; Cyclazocine; Dextromethorphan; Dextropropoxyphene; Evaluation Studies as Topic; Hemagglutination Inhibition Tests; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Radioimmunoassay; Spectrometry, Fluorescence; Substance-Related Disorders; Time Factors; Tritium

1974
Inspiratory versus expiratory efforts in pigeons: a search for selective drug influence.
    Agents and actions, 1973, Volume: 3, Issue:4

    Topics: Anesthesia; Animals; Atropine; Barbiturates; Benzoates; Chloralose; Chlorpromazine; Codeine; Columbidae; Ethanol; Methadone; Methylphenidate; Morphine; Nalorphine; Nikethamide; Noscapine; Pregnanediones; Respiration; Trachea; Urethane

1973
[Ionization constants of several narcotic analgesics and their pain relieving activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:3

    Topics: Analgesics, Opioid; Benzilates; Chemical Phenomena; Chemistry, Physical; Codeine; Dextromoramide; Dimethylamines; Kinetics; Levorphanol; Meperidine; Methadone; Morphine; Muscle Relaxants, Central; Phenylacetates; Structure-Activity Relationship

1973
Changing patterns of drug abuse in New York City.
    The American journal of drug and alcohol abuse, 1974, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Antipsychotic Agents; Barbiturates; Codeine; Dextropropoxyphene; Female; Glutethimide; Heroin Dependence; Humans; Male; Methadone; Morphine; New York City; Phenothiazines; Phenytoin; Quinine; Substance-Related Disorders

1974
Urine screening techniques employed in the detection of users of narcotics and their correlation with the nalorphine test.
    Journal of forensic sciences, 1966, Volume: 11, Issue:2

    Topics: Amphetamine; California; Cocaine; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Nalorphine; Pupil; Substance-Related Disorders

1966
A method of identifying narcotic analgesics in human urine after therapeutic doses.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Alkaloids; Analgesics; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Humans; Hydromorphone; Ion Exchange; Levorphanol; Meperidine; Methadone; Methods; Morphine; Narcotics; Pentazocine

1970
[Permeation of active morphine-like substances at their sites of antinociceptive action in the brain as a function of their lipid-solubility following intravenous and intraventricular application].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 265, Issue:5

    Topics: Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Dental Pulp Test; Fentanyl; Hydromorphone; Ketones; Kinetics; Levorphanol; Lipids; Methadone; Morphinans; Morphine; Piperidines; Rabbits; Solubility; Tritium

1970
Experiences with ESR as a tool for surveying narcotic addiction.
    Annals of the New York Academy of Sciences, 1973, Dec-31, Volume: 222

    Topics: Animals; Antibodies; Antigen-Antibody Reactions; Chromatography, Thin Layer; Cocaine; Codeine; Electron Spin Resonance Spectroscopy; Evaluation Studies as Topic; Glucuronates; Heroin; Humans; Mass Screening; Methadone; Methods; Morphine; Rabbits; Saliva; Spin Labels; Substance-Related Disorders; Time Factors

1973
Structural requirement for antitussive activity in some novel 16-substituted derivatives of 6,14-endoethenotetrahydrothebaine.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20, Issue:12

    Topics: Analgesia; Animals; Antitussive Agents; Cats; Codeine; Cough; Guinea Pigs; Methadone; Morphinans; Morphine; Rats

1968
Screening method for detection of drugs of abuse in human urine.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Alkaloids; Amphetamine; Analgesics; Barbiturates; Chlorpheniramine; Chromatography; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonists; Hot Temperature; Humans; Indicators and Reagents; Isonipecotic Acids; Meperidine; Methadone; Methods; Morphinans; Morphine; Pentazocine; Phenacetin; Phenothiazines; Quinidine; Substance-Related Disorders; Ultraviolet Rays

1971
Letter: Unsuspected opiate overdose.
    British medical journal, 1974, Aug-31, Volume: 3, Issue:5930

    Topics: Adolescent; Antidotes; Codeine; Cyclizine; Drug Combinations; Ethers, Cyclic; Female; Humans; Injections, Intravenous; Male; Methadone; Middle Aged; Morphinans; Nalorphine; Poisoning

1974
Optimization of extraction and separation of narcotics from urine.
    Clinical biochemistry, 1974, Volume: 7, Issue:3

    Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors

1974
Transport and interaction of drugs in leukocytes.
    Biochemical pharmacology, 1974, Nov-01, Volume: 23, Issue:21

    Topics: Amines; Amphetamine; Animals; Biological Transport, Active; Codeine; Drug Interactions; Fluorides; In Vitro Techniques; Kinetics; Leukocytes; Male; Methadone; Morphine; Naloxone; Pentazocine; Rats; Temperature; Time Factors

1974
[Previous opiate addictions: trial of substitutive therapy using methadone chlorhydrate].
    Annales de medecine interne, 1974, Volume: 125, Issue:5

    Topics: Administration, Oral; Adult; Ambulatory Care; Codeine; Female; Heroin Dependence; Hospitalization; Humans; Male; Methadone; Morphine Dependence; Opium; Pregnancy; Substance-Related Disorders; Time Factors

1974
Induction of physical dependence on morphine, codeine and meperidine in the rat by continuous infusion.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Codeine; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Injections, Intraperitoneal; Male; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorphine; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Vocalization, Animal

1974
Drug screening--fact of life for the nineteen seventies.
    IMS, Industrial medicine and surgery, 1972, Volume: 41, Issue:6

    Topics: Amphetamine; Barbiturates; Chromatography, Thin Layer; Codeine; Humans; Mass Screening; Methadone; Occupational Health Services; Occupational Medicine; Opium; Phenothiazines; Quinine; Substance-Related Disorders

1972
Urinalysis of 39,350 samples for drugs subject to abuse in a methadone maintenance treatment programme.
    The British journal of addiction to alcohol and other drugs, 1973, Volume: 68, Issue:4

    Topics: Barbiturates; Codeine; Humans; Mass Screening; Methadone; Morphine; Phenethylamines; Quinine; Substance-Related Disorders; United States

1973
Stability of certain drugs of abuse in urine specimens.
    Clinical chemistry, 1972, Volume: 18, Issue:11

    Topics: Amphetamine; Azides; Cocaine; Codeine; Drug Stability; Humans; Methadone; Morphine; Pharmaceutical Preparations; Phenobarbital; Secobarbital; Substance-Related Disorders; Temperature

1972
Effects of some narcotics and antagonists on synaptosomal 3 H-norepinephrine uptake.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Jun-15, Volume: 11, Issue:12

    Topics: Animals; Brain; Codeine; In Vitro Techniques; Methadone; Morphine; Nalorphine; Naloxone; Narcotics; Nerve Endings; Nerve Tissue Proteins; Norepinephrine; Pentobarbital; Pentylenetetrazole; Protein Binding; Rabbits; Synaptic Vesicles; Synaptosomes; Thebaine

1972
Ethoheptazine-monoamine oxidase inhibitor interaction in rabbits.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:9

    Topics: Alphaprodine; Amines; Analgesics; Animals; Azepines; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Interactions; Female; Fever; Isonipecotic Acids; Levallorphan; Levorphanol; Male; Methadone; Monoamine Oxidase Inhibitors; Nalorphine; Rabbits; Time Factors

1972
Opiate receptor: demonstration in nervous tissue.
    Science (New York, N.Y.), 1973, Mar-09, Volume: 179, Issue:4077

    Topics: Analgesics; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Codeine; Colchicine; Dextromethorphan; Dextropropoxyphene; Guinea Pigs; Histamine; Intestinal Mucosa; Levallorphan; Methadone; Mice; Morphine; Nalorphine; Naloxone; Phenazocine; Phenobarbital; Rats; Receptors, Drug; Serotonin; Tritium

1973
Simple gas-liquid chromatographic method for confirming the presence of alkaloids in urine.
    Clinical chemistry, 1973, Volume: 19, Issue:3

    Topics: 1-Propanol; Chloroform; Chromatography, Gas; Cocaine; Codeine; Methadone; Methods; Morphine; Solubility

1973
Analgesics and other drugs for relief of pain.
    Postgraduate medicine, 1973, Volume: 53, Issue:6

    Topics: Analgesics; Aspirin; Azepines; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Indomethacin; Methadone; Morphine; Narcotics; Pain; Pentazocine; Pyrazoles; Salicylates; Substance-Related Disorders

1973
Primary hypoventilation.
    British journal of anaesthesia, 1973, Volume: 45, Issue:6

    Topics: Adolescent; Codeine; Female; Humans; Hypoventilation; Male; Methadone; Middle Aged

1973
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2

    Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium

1973
Agonistic properties of narcotic analgesics and antagonists on the electroencephalogram and behavior in the rat and their reversal by naloxone.
    Neuropharmacology, 1973, Volume: 12, Issue:7

    Topics: Analgesics; Animals; Behavior, Animal; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Female; Meperidine; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Sleep; Time Factors

1973
The effect of narcotic analgesics on the homovanillic acid content of rat nucleus caudatus.
    European journal of pharmacology, 1973, Volume: 22, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Catalepsy; Caudate Nucleus; Codeine; Cyclazocine; Homovanillic Acid; Humans; Male; Methadone; Morphine; Muscle Tonus; Narcotics; Pentazocine; Phenylacetates; Rats; Structure-Activity Relationship

1973
Respiratory changes following reflexogenic expiratory twitches.
    Agents and actions, 1973, Volume: 3, Issue:2

    Topics: Animals; Anthracenes; Benzoates; Codeine; Columbidae; Cough; Decerebrate State; Methadone; Nalorphine; Noscapine; Pentobarbital; Pressure; Reflex; Respiration; Time Factors

1973
Effect of stimulus intensity on the potency of some analgetic agents.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:1

    Topics: Analgesics; Animals; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Levorphanol; Male; Meperidine; Methadone; Mice; Mice, Inbred Strains; Naloxone; Pentazocine; Physical Stimulation; Reaction Time; Seizures; Time Factors; Tremor

1973
Effect of midbrain raphe lesion on the antinociceptive action of morphine and other analgesics in rats.
    Psychopharmacologia, 1973, Dec-20, Volume: 33, Issue:4

    Topics: Animals; Codeine; Dextropropoxyphene; Meperidine; Mesencephalon; Methadone; Morphine; Rats; Serotonin

1973
[Ionization constants of several narcotic analgesics and their pain relieving action].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:1

    Topics: Analgesics; Codeine; Dextromoramide; Dimethylamines; Diphenylacetic Acids; Ethers, Cyclic; Hydrogen-Ion Concentration; Ions; Kinetics; Levorphanol; Mathematics; Meperidine; Methadone; Morphinans; Morphine; Narcotics; Piperidines

1973
Characteristics of the "receptor" for narcotic analgesics in synaptic plasma membrane fraction from rat brain.
    Acta pharmacologica et toxicologica, 1973, Volume: 33, Issue:5

    Topics: Acetylcholine; Animals; Binding, Competitive; Brain Stem; Cerebral Cortex; Chloromercuribenzoates; Codeine; Dextromethorphan; Ethylmaleimide; Female; Heroin; In Vitro Techniques; Levorphanol; Methadone; Morphinans; Morphine; Nalorphine; Naloxone; Physostigmine; Rats; Receptors, Drug; Structure-Activity Relationship; Subcellular Fractions; Synaptic Membranes; Tritium

1973
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders

1974
Technique for rapidly separating drugs from biological samples.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amphetamine; Chromatography, Gas; Codeine; Evaluation Studies as Topic; Humans; Methadone; Methamphetamine; Methods; Pharmaceutical Preparations; Quinine; Substance-Related Disorders; Time Factors

1974
Thiazine dye antagonism of opioid lethality in mice.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3

    Topics: Animals; Codeine; Dextropropoxyphene; Drug Synergism; Hexobarbital; Lethal Dose 50; Levorphanol; Male; Meperidine; Methadone; Methylene Blue; Mice; Morphinans; Morphine; Sleep; Thiazines; Time Factors; Tolonium Chloride

1974
Evaluation of a latex agglutination-inhibition slide pregnancy test (Pregnosis).
    Obstetrics and gynecology, 1974, Volume: 43, Issue:5

    Topics: Abortion, Spontaneous; Adolescent; Adult; Antidepressive Agents; Chorionic Gonadotropin; Codeine; Contraceptives, Oral; Diagnostic Errors; False Negative Reactions; False Positive Reactions; Female; Humans; Latex Fixation Tests; Male; Methadone; Morphine; Phenothiazines; Pregnancy; Pregnancy Complications; Pregnancy Tests, Immunologic; Pregnancy, Ectopic; Proteinuria

1974
Born with a habit. Infants of drug-addicted mothers.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Barbiturates; Camphor; Chlorpromazine; Codeine; Diazepam; Female; Fetus; Heroin; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal Age; Methadone; Opium; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome; Substance-Related Disorders

1974
New molecular complexes of methadone, its congeners and some other opiates with copper and iron.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:2

    Topics: Chemical Phenomena; Chemistry; Chlorides; Codeine; Copper; Crystallization; Dextropropoxyphene; Drug Stability; Heroin Dependence; Humans; Iron; Meperidine; Methadone; Solutions; Stereoisomerism

1974
Confirmed identification of biotransformed drugs of abuse in urine.
    American journal of clinical pathology, 1972, Volume: 57, Issue:1

    Topics: Amphetamine; Analgesics; Barbiturates; Biotransformation; Caffeine; Cannabis; Chromatography, Gas; Chromatography, Thin Layer; Codeine; Humans; Hydrogen-Ion Concentration; Imipramine; Indicators and Reagents; Methadone; Morphine; Nicotine; Pharmaceutical Preparations; Procaine; Skin; Spectrum Analysis; Substance-Related Disorders; Tranquilizing Agents

1972
Mini thin-layer chromatography in the detection of narcotics in urine from subjects on a methadone maintenance program.
    Journal of chromatography, 1972, Mar-01, Volume: 65, Issue:3

    Topics: Chromatography, Thin Layer; Codeine; Colorimetry; Humans; Meperidine; Methadone; Methods; Morphine; Narcotics; Substance-Related Disorders

1972
Eosinophilia and drug abuse.
    Annals of allergy, 1972, Volume: 30, Issue:11

    Topics: Amphetamine; Barbiturates; Cannabis; Cocaine; Codeine; Eosinophilia; Heroin; Humans; Lysergic Acid Diethylamide; Male; Mescaline; Methadone; Morphine; Substance-Related Disorders

1972
Blood-brain barrier: penetration of morphine, codeine, heroin, and methadone after carotid injection.
    Science (New York, N.Y.), 1972, Dec-01, Volume: 178, Issue:4064

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Carbon Isotopes; Carotid Arteries; Codeine; Heroin; Injections, Intravenous; Mannitol; Methadone; Morphine; Rats; Time Factors; Tritium

1972
An implanted reservoir of morphine solution for rapid induction of physical dependence in rats.
    British journal of pharmacology, 1971, Volume: 41, Issue:3

    Topics: Animals; Body Weight; Codeine; Cyclazocine; Defecation; Female; Humans; Injections, Subcutaneous; Methadone; Methods; Morphine; Nalorphine; Pentazocine; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1971
Effects of narcotic analgesics and antagonists on the in vivo release of acetylcholine from the cerebral cortex of the cat.
    British journal of pharmacology, 1971, Volume: 43, Issue:1

    Topics: Acetylcholine; Analgesia; Analgesics; Animals; Bridged-Ring Compounds; Cats; Cerebral Cortex; Chlorpromazine; Codeine; Dextropropoxyphene; Female; Furans; Ketones; Levallorphan; Male; Meperidine; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenanthrenes

1971
Absence of major medical complications among chronic opiate addicts.
    The British journal of addiction to alcohol and other drugs, 1970, Volume: 65, Issue:2

    Topics: Age Factors; Aged; Codeine; Heroin; Humans; Injections; Male; Methadone; Middle Aged; Morphine; Opium; Patient Readmission; Phenytoin; Substance-Related Disorders; Time Factors

1970
Inhibition of cell growth and the synthesis of ribonucleic acid and protein in HeLa cells by morphinans and related compounds.
    Molecular pharmacology, 1969, Volume: 5, Issue:1

    Topics: Amino Acids; Carbon Isotopes; Codeine; Culture Techniques; HeLa Cells; Leucine; Levallorphan; Levorphanol; Methadone; Morphinans; Phenazocine; Protein Biosynthesis; Ribosomes; RNA; Thebaine; Time Factors

1969
[Principles and risks of drug treatment of pain].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans; Imipramine; Levallorphan; Levorphanol; Methadone; Morphine; Pain; Phenacetin; Phenylbutazone; Pyrazoles; Salicylamides; Salicylates; Sulfonic Acids

1969
Action of codeine, pethidine and methadone on the operant behavior of the rat.
    Psychopharmacologia, 1970, Volume: 17, Issue:1

    Topics: Animals; Avoidance Learning; Codeine; Conditioning, Operant; Depression, Chemical; Male; Meperidine; Methadone; Rats; Reinforcement, Psychology

1970
Drug action on tail shock-induced vocalization in mice and its relevance to analgesia.
    European journal of pharmacology, 1970, Volume: 9, Issue:2

    Topics: Analgesia; Animals; Cerebral Cortex; Chlorpromazine; Codeine; Cyclazocine; Electric Stimulation; Hydroxyzine; Levallorphan; Male; Methadone; Methotrimeprazine; Mice; Morphinans; Morphine; Nalorphine; Narcotic Antagonists; Narcotics; Pentazocine; Tail; Tranquilizing Agents; Vocalization, Animal

1970
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhydramine; Histamine; Humans; Meperidine; Meprobamate; Methadone; Methods; Morphine Dependence; Pentazocine; Pyrrolidines; Rats; Salicylates; Serotonin; Substance Withdrawal Syndrome

1970
Pharmacology of narcotics and antagonists as related to drug abuse.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Codeine; Heroin; Humans; Levallorphan; Meperidine; Methadone; Morphine; Morphine Dependence; Nalorphine; Narcotic Antagonists; Stereoisomerism; Substance-Related Disorders

1971
[Characteristic expiratory thrusts in pigeons].
    Helvetica physiologica et pharmacologica acta, 1967, Volume: 25, Issue:3

    Topics: Amino Alcohols; Animals; Benzoates; Chlorpromazine; Codeine; Columbidae; Cough; Electric Stimulation; Exploratory Behavior; Larynx; Methadone; Nikethamide; Psychopharmacology; Psychophysiology; Respiration; Scopolamine; Sodium Chloride

1967
Antagonism of the analgesic effect of morphine and other drugs by p-chlorophenylalanine, a serotonin depletor.
    Psychopharmacologia, 1968, Volume: 12, Issue:4

    Topics: Analgesia; Animals; Brain; Codeine; Dextropropoxyphene; Electroshock; Male; Methadone; Morphine; Pain; Phenylalanine; Rats; Serotonin; Serotonin Antagonists

1968
[On characterization of the bradykinin effect on smooth muscle].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:7

    Topics: Animals; Bradykinin; Bronchi; Codeine; Fentanyl; Guinea Pigs; Ileum; Levallorphan; Methadone; Morphine; Muscle, Smooth; Nalorphine; Piperidines; Thebaine

1968
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
    Journal of chromatography, 1969, May-20, Volume: 41, Issue:3

    Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine

1969
Response to opioids in three patients with restless legs syndrome.
    The American journal of psychiatry, 1984, Volume: 141, Issue:8

    Topics: Codeine; Female; Humans; Male; Methadone; Middle Aged; Myoclonus; Oxycodone; Receptors, Opioid; Restless Legs Syndrome; Sleep; Sleep Wake Disorders

1984
Affinities of some common opioid analgesics towards four binding sites in mouse brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 328, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Binding Sites; Brain; Codeine; Cyclazocine; Dextropropoxyphene; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Methionine; Ethylketocyclazocine; In Vitro Techniques; Membranes; Methadone; Mice; Models, Biological; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1984
Opiates and thermoregulation in mice. I. Agonists.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2

    Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone

1980
Clinical effects of parenteral narcotics in hospitalized medical patients.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Codeine; Drug Utilization; Female; Humans; Hydromorphone; Injections; Male; Methadone; Morphine; Narcotics; Opium

1980
Zinc tannate salts of heroin, LAAM and hydromorphone attenuate opiate withdrawal syndrome.
    Psychopharmacology, 1980, Volume: 68, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Codeine; Delayed-Action Preparations; Heroin; Humans; Hydromorphone; Male; Methadone; Methadyl Acetate; Opioid-Related Disorders; Rats; Substance Withdrawal Syndrome; Zinc

1980
Descriptive epidemiology of mortality in New Jersey due to combinations of codeine and glutethimide.
    American journal of epidemiology, 1984, Volume: 119, Issue:2

    Topics: Adult; Codeine; Drug Interactions; Epidemiologic Methods; Female; Glutethimide; Heroin; Humans; Male; Methadone; New Jersey; Substance-Related Disorders

1984
Determination of oxycodone in human plasma by high-performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1984, Jun-08, Volume: 308

    Topics: Chromatography, High Pressure Liquid; Codeine; Electrochemistry; Humans; Kinetics; Methadone; Oxycodone

1984
Antitussive effect of the optical isomers of mu, kappa and sigma opiate agonists/antagonists in the cat.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Antitussive Agents; Blood Pressure; Cats; Codeine; Cyclazocine; Dextromethorphan; Female; Heart Rate; Male; Methadone; Morphine; Narcotics; Phenazocine; Stereoisomerism

1983
Determination of therapeutic concentrations of codeine by high-performance liquid chromatography.
    Journal of chromatography, 1983, May-13, Volume: 274

    Topics: Chromatography, High Pressure Liquid; Codeine; Humans; Methadone; Time Factors

1983
Protein concentration effects on binding of 14C-codeine, 14C-morphine, and 3H-methadone to human serum albumin.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:1

    Topics: Carbon Radioisotopes; Codeine; Humans; Methadone; Morphine; Protein Binding; Serum Albumin; Tritium

1980
[Comparative pharmacodynamics of methadone, buprenorphine and codeine].
    Annales de medecine interne, 1994, Volume: 145 Suppl 3

    Topics: Administration, Oral; Biotransformation; Buprenorphine; Codeine; Drug Tolerance; Humans; Methadone; Time Factors

1994
[Substitution treatment of drug-dependent patients].
    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)), 1995, Volume: 57, Issue:1

    Topics: Codeine; Drug and Narcotic Control; Germany; Health Policy; Heroin Dependence; Humans; Methadone; National Health Programs; Opioid-Related Disorders; Substance-Related Disorders

1995
The efficacy of management of acute dental pain.
    British dental journal, 1995, Feb-25, Volume: 178, Issue:4

    Topics: Analgesics, Opioid; Codeine; Cyclizine; Drug Combinations; Drug Prescriptions; Facial Pain; Health Services Misuse; Humans; Methadone; Practice Patterns, Physicians'; Toothache

1995
Simultaneous determination of drugs of abuse (opiates, cocaine and amphetamine) in human hair by GC/MS and its application to a methadone treatment program.
    Forensic science international, 1993, Volume: 63, Issue:1-3

    Topics: Adult; Amphetamine; Calibration; Cocaine; Codeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Male; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders

1993
Poppy tea dependence.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 163

    Topics: Adult; Codeine; Dose-Response Relationship, Drug; Humans; Male; Methadone; Opioid-Related Disorders; Opium; Papaver; Plants, Medicinal; Substance Withdrawal Syndrome; Tea

1993
Non-opioid antitussives and methadone differentially influence hippocampal long-term potentiation in freely moving rats.
    European journal of pharmacology, 1993, Feb-16, Volume: 231, Issue:3

    Topics: Animals; Codeine; Dextromethorphan; Drug Synergism; Electric Stimulation; Evoked Potentials; Hippocampus; Male; Methadone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1993
[Drug withdrawal under anesthesia--an alternative to substitution therapy. Model project in a Bavarian district hospital. Interview by Dr. rer. nat. Anita Schweiger].
    Fortschritte der Medizin, 1996, Aug-30, Volume: 114, Issue:24

    Topics: Anesthesia, General; Codeine; Heroin Dependence; Humans; Methadone; Narcotic Antagonists; Pilot Projects; Treatment Outcome

1996
[Opiate withdrawal in anesthesia (forced narcotic withdrawal, "turbo withdrawal") in narcotic dependence. Changes in withdrawal treatment--wishes and reality].
    Der Nervenarzt, 1996, Volume: 67, Issue:9

    Topics: Adult; Anesthesia, General; Animals; Codeine; Female; Heroin Dependence; Humans; Male; Methadone; Naloxone; Narcotic Antagonists; Pilot Projects; Substance Withdrawal Syndrome; Treatment Outcome

1996
[Changes in the pattern of opioid analgesic consumption in Spain].
    Medicina clinica, 1997, Sep-13, Volume: 109, Issue:8

    Topics: Administration, Oral; Administration, Rectal; Analgesics, Opioid; Buprenorphine; Codeine; Databases as Topic; Dextropropoxyphene; Drug Prescriptions; Humans; Injections, Intravenous; Linear Models; Meperidine; Methadone; Morphine; Pentazocine; Spain; Tilidine; Tramadol

1997
A method for the confirmation and identification of drugs of misuse in urine using solid phase extraction and gas-liquid chromatography with mass spectrometry.
    Journal of clinical pathology, 1998, Volume: 51, Issue:4

    Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Methadone; Morphine; Morphine Derivatives; Sensitivity and Specificity; Substance Abuse Detection

1998
Maintenance treatment of opiate addicts in Germany with medications containing codeine--results of a follow-up study.
    Addiction (Abingdon, England), 1998, Volume: 93, Issue:8

    Topics: Adult; Codeine; Female; Follow-Up Studies; Germany; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders

1998
[Pain therapy].
    Presse medicale (Paris, France : 1983), 1998, Dec-12, Volume: 27, Issue:39

    Topics: Adult; Age Factors; Analgesics; Analgesics, Opioid; Child; Codeine; Humans; Methadone; Neurosurgery; Pain Management; Pain, Intractable; Pain, Postoperative; Tramadol

1998
Prescribing and dispensing for drug misusers in primary care: current practice in Scotland.
    Family practice, 1999, Volume: 16, Issue:4

    Topics: Analgesics, Opioid; Anti-Anxiety Agents; Codeine; Community Pharmacy Services; Diazepam; Drug Prescriptions; Drug Utilization; Humans; Methadone; Narcotics; Practice Patterns, Physicians'; Primary Health Care; Scotland; Substance-Related Disorders; Surveys and Questionnaires; Temazepam

1999
[Initial effects of the 1998 revised narcotic law in substitute drug treatment of narcotic dependent patients--results of a physician survey].
    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)), 2000, Volume: 62, Issue:1

    Topics: Attitude of Health Personnel; Codeine; Drug and Narcotic Control; Germany; Humans; Methadone; Opioid-Related Disorders; Patient Acceptance of Health Care

2000
Safety, efficacy, and long-term results of a modified version of rapid opiate detoxification under general anaesthesia: a prospective study in methadone, heroin, codeine and morphine addicts.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:3

    Topics: Adult; Anesthesia, General; Codeine; Female; Heroin Dependence; Humans; Male; Methadone; Morphine Dependence; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Prospective Studies; Substance Withdrawal Syndrome

2000
Modified liquid junction interface for nonaqueous capillary electrophoresis-mass spectrometry.
    Electrophoresis, 2000, Volume: 21, Issue:15

    Topics: Codeine; Electrophoresis, Capillary; Equipment Design; Indicators and Reagents; Levorphanol; Methadone; Morphine; Pentazocine; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2000
Dihydrocodeine: a useful tool in the detoxification of methadone-maintained patients.
    Journal of substance abuse treatment, 2000, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Analgesics, Opioid; Codeine; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Methadone; Opioid-Related Disorders; Retrospective Studies; Treatment Outcome

2000
[Opioids. Pharmacology, clinic, prospectives for an extensive use].
    Recenti progressi in medicina, 2000, Volume: 91, Issue:12

    Topics: Analgesics, Opioid; Codeine; Drug Tolerance; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Oxycodone; Receptors, Opioid; Tramadol

2000
Myocardial Infarction associated with methadone and/or dihydrocodeine.
    European addiction research, 2001, Volume: 7, Issue:1

    Topics: Adult; Analgesics, Opioid; Codeine; Humans; Hypercholesterolemia; Male; Methadone; Myocardial Infarction; Obesity; Opioid-Related Disorders; Smoking

2001
Determination of opiates in serum, saliva and hair addicted persons.
    Przeglad lekarski, 2001, Volume: 58, Issue:4

    Topics: Adult; Codeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Hydrogen-Ion Concentration; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Opioid-Related Disorders; Saliva

2001
Detection of opiate use in a methadone maintenance treatment population with the CEDIA 6-acetylmorphine and CEDIA DAU opiate assays.
    Journal of analytical toxicology, 2001, Volume: 25, Issue:7

    Topics: Adolescent; Adult; Cocaine-Related Disorders; Codeine; False Positive Reactions; Female; Gas Chromatography-Mass Spectrometry; Heroin Dependence; Humans; Immunoenzyme Techniques; Male; Methadone; Middle Aged; Morphine; Morphine Derivatives; Narcotics; Sensitivity and Specificity; Substance Abuse Detection; Workplace

2001
Alcohol consumption in heroin users, methadone-substituted and codeine-substituted patients--frequency and correlates of use.
    European addiction research, 2003, Volume: 9, Issue:1

    Topics: Adult; Alcohol Drinking; Alcoholism; Codeine; Comorbidity; Confidence Intervals; Female; Heroin Dependence; Humans; Logistic Models; Male; Methadone; Odds Ratio; Retrospective Studies

2003
Strabismus in infants of opiate-dependent mothers.
    Acta paediatrica (Oslo, Norway : 1992), 2003, Volume: 92, Issue:3

    Topics: Australia; Codeine; Cross-Sectional Studies; Female; Heroin; Humans; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Neonatal Screening; Opioid-Related Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Severity of Illness Index; Strabismus

2003
The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum.
    British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:1

    Topics: Acetylcholine; Codeine; Drug Tolerance; Guinea Pigs; Heroin; Ileum; Intestines; Meperidine; Methadone; Morphine; Nalorphine

1957
[The problem of cough drug addiction].
    Die Medizinische, 1957, Mar-16, Issue:11

    Topics: Behavior, Addictive; Codeine; Cough; Ephedrine; Ethylmorphine; Humans; Methadone; Substance-Related Disorders

1957
[Dextromethadone and its antitussive effect].
    Nordisk medicin, 1957, Apr-25, Volume: 57, Issue:17

    Topics: Antitussive Agents; Codeine; Cough; Methadone

1957
Comparative effects of analgesics on pain threshold, respiratory frequency and gastrointestinal propulsion.
    British journal of pharmacology and chemotherapy, 1959, Volume: 14, Issue:1

    Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antipyretics; Cell Respiration; Codeine; Dextromoramide; Gastrointestinal Tract; Guinea Pigs; Meperidine; Methadone; Morphine; Nalorphine; Pain; Pain Threshold; Rats; Respiration; Respiratory Rate

1959
Multiple toe-pinch method for testing analgesic drugs.
    British journal of pharmacology and chemotherapy, 1961, Volume: 17

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Chlorpromazine; Codeine; Guinea Pigs; Humans; Lysergic Acid Diethylamide; Male; Meperidine; Methadone; Morphine; Nalorphine; Phencyclidine; Phthalic Acids; Rats; Toes

1961
[Behavior modifiers inthe study of bile ducts. (Combined action of morphine substances and cholecystokinin)].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1963, Volume: 44

    Topics: Ampulla of Vater; Bile Ducts; Cholecystokinin; Codeine; Dextromoramide; Hydromorphone; Meperidine; Methadone; Morphine; Opium

1963
The biological disposition of morphine and its surrogates.
    Bulletin of the World Health Organization, 1962, Volume: 27

    Topics: Codeine; Heroin; Humans; Methadone; Morphine; Nalorphine; Narcotic Antagonists

1962
A DIRECT TITRIMETRIC METHOD FOR THE DETERMINATION OF SOME ORGANIC BASES IN PHARMACEUTICAL PREPARATIONS.
    The Journal of pharmacy and pharmacology, 1963, Volume: 15

    Topics: Atropine; Chemistry, Pharmaceutical; Codeine; Meperidine; Methadone; Pharmacy; Research

1963
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jan-01, Volume: 147

    Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology

1964
ELEVATION OF PLASMA HISTAMINE LEVELS IN THE DOG FOLLOWING ADMINISTRATION OF MUSCLE RELAXANTS, OPIATES AND MACROMOLECULAR POLYMERS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 143

    Topics: Acacia; Analgesics, Opioid; Blood Chemical Analysis; Codeine; Dextrans; Diatrizoate; Dogs; Histamine; Meperidine; Mesylates; Methadone; Morphine; Muscle Relaxants, Central; Niacin; Nicotinic Acids; Pharmacology; Povidone; Research; Starch; Succinylcholine; Tubocurarine

1964
TO-DAYS DRUGS. COUGH SUPPRESSANTS.
    British medical journal, 1964, May-02, Volume: 1, Issue:5391

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antitussive Agents; Codeine; Heroin; Humans; Ion Exchange Resins; Methadone; Noscapine; Parasympatholytics; Pharmacology

1964
ANALGESICS FOR THE RELIEF OF PAIN. I. NARCOTIC ANALGESICS.
    Wisconsin medical journal, 1964, Volume: 63

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pain; Phenazocine; Piperidines

1964
USE OF DRUGS IN THE TREATMENT OF RHEUMATOID ARTHRITIS.
    Physiotherapy, 1964, Volume: 50

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Codeine; Humans; Hydroxychloroquine; Methadone; Morphine; Oxyphenbutazone; Phenylbutazone; Toxicology

1964
EXPERIMENTAL NARCOTIC ADDICTION.
    Scientific American, 1964, Volume: 210

    Topics: Animals; Codeine; Conditioning, Psychological; Equipment and Supplies; Haplorhini; Injections, Intravenous; Meperidine; Methadone; Morphine Dependence; Nalorphine; Opioid-Related Disorders; Rats; Substance-Related Disorders

1964
BARBITURATE USE IN NARCOTIC ADDICTS.
    JAMA, 1964, Aug-03, Volume: 189

    Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine Dependence; Narcotics; Opium; Pentobarbital; Seizures; Statistics as Topic; Substance-Related Disorders; Toxicology; Urea

1964
A RAPID SCREENING TEST FOR POTENTIAL ADDICTION LIABILITY OF NEW ANALGESIC AGENTS.
    Toxicology and applied pharmacology, 1964, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior, Addictive; Codeine; Dextropropoxyphene; Heroin; Hydromorphone; Meperidine; Methadone; Mice; Morphine; Phenazocine; Research; Substance-Related Disorders; Toxicology

1964
GAS CHROMATOGRAPHY OF HIGH-BOILING AMINES. II. DETERMINATION OF AMINES IN LOW CONCENTRATION.
    Acta pharmaceutica Suecica, 1964, Volume: 1

    Topics: Amines; Chemistry, Pharmaceutical; Chromatography; Chromatography, Gas; Cocaine; Codeine; Ephedrine; Lidocaine; Methadone; Morphine; Pharmacy; Promazine; Research; Scopolamine

1964
RELATIVE POTENCY OF CODEINE, METHADONE AND DIHYDROMORPHINONE TO MORPHINE IN SELF-MAINTAINED ADDICT RATS.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Jan-08, Volume: 249

    Topics: Codeine; Hydromorphone; Methadone; Morphine; Morphine Dependence; Periodicity; Pharmacology; Rats; Research

1965
A METHOD FOR THE THIN-LAYER CHROMATOGRAPHY OF ANALGESIC DRUGS AND RELATED COMPOUNDS IN NON-AQUEOUS SYSTEMS.
    Journal of chromatography, 1965, Volume: 17

    Topics: Ammonia; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Azepines; Chromatography; Chromatography, Thin Layer; Cocaine; Codeine; Dextropropoxyphene; Isonipecotic Acids; Meperidine; Methadone; Morphine; Research

1965
[ON THE MORPHINE-LIKE PROPERTIES OF A NEW ANTITUSSIVE (ISOAMINIL; PERACON, MULLATUSS)].
    Die Pharmazie, 1964, Volume: 19

    Topics: Acetonitriles; Antitussive Agents; Codeine; Cyanides; Electron Transport Complex IV; Methadone; Mice; Morphine; Nalorphine; Pharmacology; Rats; Research; Respiration; Toxicology

1964
Rat tissue levels of carbon-14 labeled analgetics as related to pharmacological activity.
    The Journal of pharmacology and experimental therapeutics, 1955, Volume: 113, Issue:3

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Central Nervous System; Codeine; Methadone; Morphine; Rats

1955
Comparison of the antinociceptive effect of morphine, methadone, buprenorphine and codeine in two substrains of Sprague-Dawley rats.
    European journal of pharmacology, 2004, May-10, Volume: 492, Issue:1

    Topics: Analgesics; Animals; Buprenorphine; Codeine; Injections, Subcutaneous; Male; Methadone; Morphine; Morphine Derivatives; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors

2004
Intravenous ketamine infusion as an adjuvant to morphine in a 2-year-old with severe cancer pain from metastatic neuroblastoma.
    Journal of pediatric hematology/oncology, 2004, Volume: 26, Issue:10

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Child, Preschool; Codeine; Drug Therapy, Combination; Dyspnea; Fatal Outcome; Female; Hallucinations; Humans; Infusions, Intravenous; Ketamine; Methadone; Morphine; Neuroblastoma; Pain, Intractable; Palliative Care; Quality of Life

2004
The clinical management of substance misusers in police custody -- a survey of current practice.
    Journal of clinical forensic medicine, 2005, Volume: 12, Issue:4

    Topics: Analgesics, Opioid; Attitude of Health Personnel; Codeine; Female; Forensic Medicine; Humans; Male; Methadone; Narcotics; Police; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prisoners; Substance Withdrawal Syndrome; Surveys and Questionnaires; United Kingdom

2005
The prescribing of methadone and other opioids to addicts: national survey of GPs in England and Wales.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2005, Volume: 55, Issue:515

    Topics: Analgesics, Opioid; Buprenorphine; Codeine; Cohort Studies; England; Family Practice; Female; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders; Organizational Policy; Practice Patterns, Physicians'; Wales

2005
Comparative actions of the opioid analgesics morphine, methadone and codeine in rat models of peripheral and central neuropathic pain.
    Pain, 2005, Volume: 116, Issue:3

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Codeine; Disease Models, Animal; Male; Methadone; Morphine; Motor Activity; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Rotarod Performance Test; Sciatic Neuropathy; Spinal Cord Injuries; Time Factors

2005
The quantitative analysis of heroin, methadone and their metabolites and the simultaneous detection of cocaine, acetylcodeine and their metabolites in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Sep-25, Volume: 824, Issue:1-2

    Topics: Administration, Inhalation; Chromatography, High Pressure Liquid; Cocaine; Codeine; Heroin; Heroin Dependence; Humans; Methadone; Narcotics; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Time Factors

2005
HPLC-DAD determination of opioids, cocaine and their metabolites in plasma.
    Forensic science international, 2006, Aug-10, Volume: 161, Issue:1

    Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Humans; Male; Methadone; Morphine; Morphine Derivatives; Pyrrolidines

2006
Co-consumption of benzodiazepines in heroin users, methadone-substituted and codeine-substituted patients.
    Journal of addictive diseases, 2005, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Benzodiazepines; Codeine; Comorbidity; Female; Heroin Dependence; Humans; Logistic Models; Male; Methadone; Middle Aged; Narcotics; Retrospective Studies; Risk Factors; Substance-Related Disorders

2005
Expression, purification, and characterization of mouse CYP2d22.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Amino Acid Sequence; Animals; Baculoviridae; Cell Line; Cloning, Molecular; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dealkylation; Dextromethorphan; Enzyme Inhibitors; Fluoxetine; Insecta; Ketoconazole; Kinetics; Methadone; Mice; Molecular Sequence Data; Molecular Weight; Quinidine; Sequence Homology, Amino Acid; Substrate Specificity

2006
Substance abuse in pregnancy: opioid substitution in a northern Ireland maternity unit.
    The Ulster medical journal, 2006, Volume: 75, Issue:3

    Topics: Adult; Buprenorphine; Codeine; Female; Heroin Dependence; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methadone; Neonatal Abstinence Syndrome; Northern Ireland; Obstetrics and Gynecology Department, Hospital; Perinatal Care; Pregnancy; Pregnancy Complications; Risk Assessment; Substance Abuse Detection

2006
Clinical update: codeine maintenance in opioid dependence.
    Lancet (London, England), 2007, Aug-18, Volume: 370, Issue:9587

    Topics: Adult; Analgesics, Opioid; Australia; Buprenorphine; Codeine; Europe; Health Policy; Heroin; Humans; Methadone; Opioid-Related Disorders; Treatment Outcome; United States

2007
Microwave-assisted extraction and HPLC-DAD determination of drugs of abuse in human plasma.
    Journal of analytical toxicology, 2007, Volume: 31, Issue:7

    Topics: Calibration; Chromatography, High Pressure Liquid; Cocaine; Codeine; Forensic Medicine; Humans; Illicit Drugs; Methadone; Microwaves; Morphine; Pyrrolidines; Reproducibility of Results; Solvents; Spectrophotometry, Atomic; Substance Abuse Detection

2007
Inhibition of succinic oxidase system by meperidine, methadon, morphine, and codeine.
    The Journal of pharmacology and experimental therapeutics, 1949, Volume: 95, Issue:2

    Topics: Codeine; Coloring Agents; Meperidine; Methadone; Morphine; Oxidoreductases; Peroxidase; Peroxidases; Succinate Dehydrogenase

1949
Development and validation of a solid-phase extraction gas chromatography-mass spectrometry method for the simultaneous quantification of methadone, heroin, cocaine and metabolites in sweat.
    Analytical and bioanalytical chemistry, 2008, Volume: 392, Issue:1-2

    Topics: Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Methadone; Morphine Derivatives; Solid Phase Extraction; Sweat

2008
Cocaine and opiate concentrations in hair from subjects in a heroin maintenance program in comparison to a methadone substituted group.
    International journal of legal medicine, 2009, Volume: 123, Issue:5

    Topics: Cocaine; Codeine; Dopamine Uptake Inhibitors; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Heroin Dependence; Humans; Linear Models; Methadone; Narcotics; Substance Abuse Detection

2009
Codeine misuse among service users on a methadone treatment programme.
    Irish journal of medical science, 2010, Volume: 179, Issue:3

    Topics: Adult; Analgesics, Opioid; Codeine; Female; Humans; Ireland; Male; Methadone; Military Personnel; Opiate Substitution Treatment; Substance-Related Disorders

2010
In vitro-in vivo extrapolation predicts drug-drug interactions arising from inhibition of codeine glucuronidation by dextropropoxyphene, fluconazole, ketoconazole, and methadone in humans.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 334, Issue:2

    Topics: Analgesics, Opioid; Animals; Cattle; Codeine; Dextropropoxyphene; Drug Interactions; Fluconazole; Glucuronosyltransferase; Humans; In Vitro Techniques; Ketoconazole; Methadone; Microsomes, Liver; Models, Biological; Serum Albumin, Bovine

2010
Determination of stimulants and narcotics as well as their in vitro metabolites by online CE-ESI-MS.
    Electrophoresis, 2011, Volume: 32, Issue:3-4

    Topics: 2-Propanol; Amphetamine; Animals; Codeine; Electrophoresis, Capillary; Ephedrine; Heroin; Hydrogen-Ion Concentration; Male; Meperidine; Methadone; Microsomes, Liver; Narcotics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tetracaine

2011
Oral fluid results compared to self reports of recent cocaine and heroin use by methadone maintenance patients.
    Forensic science international, 2012, Feb-10, Volume: 215, Issue:1-3

    Topics: Cocaine; Cocaine-Related Disorders; Codeine; Heroin; Heroin Dependence; Humans; Methadone; Morphine; Morphine Derivatives; Narcotics; Opiate Substitution Treatment; Saliva; Self Report; Substance Abuse Detection

2012
Drug screening of whole blood by ultra-performance liquid chromatography-tandem mass spectrometry.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:5

    Topics: Buprenorphine; Chromatography, Liquid; Cocaine; Codeine; Dronabinol; Ethylmorphine; Humans; Illicit Drugs; Methadone; Morphine; Oxycodone; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry

2011
Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone- and buprenorphine-maintained subjects.
    British journal of clinical pharmacology, 2012, Volume: 73, Issue:5

    Topics: Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Codeine; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Female; Genotype; Glucuronosyltransferase; Humans; Male; Methadone; Middle Aged; Statistics as Topic; Young Adult

2012
Is maternal opioid use hazardous to breast-fed infants?
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:1

    Topics: Age Factors; Analgesics, Opioid; Breast Feeding; Buprenorphine; Codeine; Female; Humans; Hydrocodone; Infant; Infant, Newborn; Meperidine; Methadone; Milk, Human; Morphine; Oxycodone

2012
Comparison of fatal poisonings by prescription opioids.
    Forensic science international, 2012, Oct-10, Volume: 222, Issue:1-3

    Topics: Accidents; Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Central Nervous System Depressants; Codeine; Dextropropoxyphene; Drug Overdose; Ethanol; Fentanyl; Finland; Forensic Toxicology; Humans; Hypnotics and Sedatives; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Poisoning; Prescription Drug Misuse; Suicide; Tramadol; Young Adult

2012
The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.
    Forensic science international, 2013, Apr-10, Volume: 227, Issue:1-3

    Topics: Adult; Anesthetics, Local; Antitussive Agents; Bile; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Citalopram; Codeine; Dextromethorphan; Drug Contamination; Drug Overdose; Drug Users; Female; Forensic Pathology; Forensic Toxicology; Gastrointestinal Contents; Humans; Illicit Drugs; Kidney; Lidocaine; Liver; Lung; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Pyrrolidines; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Vitreous Body

2013
Determination of stimulants using gas chromatography/high-resolution time-of-flight mass spectrometry and a soft ionization source.
    Rapid communications in mass spectrometry : RCM, 2012, Dec-15, Volume: 26, Issue:23

    Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Codeine; Dopamine Uptake Inhibitors; Equipment Design; GABA Antagonists; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Ions; Methadone; Narcotics; Nicotine; Nikethamide; Norbornanes; Pentylenetetrazole; Phenmetrazine; Sensitivity and Specificity

2012
Methadone, codeine and acute haemorrhagic necrotising pancreatitis: which came first?
    Forensic science international, 2013, Mar-10, Volume: 226, Issue:1-3

    Topics: Abdominal Pain; Adult; Analgesics, Opioid; Codeine; Fatty Liver; Female; Hemorrhage; Humans; Liver Cirrhosis; Methadone; Narcotics; Opiate Substitution Treatment; Pancreatitis, Acute Necrotizing

2013
A preliminary evaluation of the effects of opioids on innate and adaptive human in vitro immune function.
    BMJ supportive & palliative care, 2014, Volume: 4, Issue:4

    Topics: Adaptive Immunity; Adult; Analgesics, Opioid; Buprenorphine; Codeine; Fentanyl; Humans; Immunity, Innate; Interleukin-2; Interleukin-6; Leukocytes, Mononuclear; Methadone; Monocytes; Morphine; Neutrophils; Oxycodone; Phagocytosis; Respiratory Burst; Tramadol

2014
Comprehensive automation of the solid phase extraction gas chromatographic mass spectrometric analysis (SPE-GC/MS) of opioids, cocaine, and metabolites from serum and other matrices.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:18

    Topics: Acetamides; Analgesics, Opioid; Automation; Cocaine; Codeine; Flunitrazepam; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Robotics; Solid Phase Extraction; Substance Abuse Detection; Trimethylsilyl Compounds

2014
Simultaneous determination of drugs of abuse and their main metabolites using pressurized liquid extraction and liquid chromatography-tandem mass spectrometry.
    Talanta, 2014, Volume: 125

    Topics: Calibration; Chromatography, Liquid; Cocaine; Codeine; Methadone; Morphine; Reproducibility of Results; Sewage; Solvents; Spectrometry, Mass, Electrospray Ionization; Substance-Related Disorders; Tandem Mass Spectrometry; Temperature; Water Pollutants, Chemical

2014
Prevalence of heroin markers in urine for pain management patients.
    Forensic science international, 2014, Volume: 243

    Topics: Analgesics, Opioid; Biomarkers; Buprenorphine; Chromatography, Liquid; Chronic Pain; Codeine; Heroin; Heroin Dependence; Humans; Illicit Drugs; Methadone; Morphine Derivatives; Pain Clinics; Tandem Mass Spectrometry

2014
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
Failure to identify or effectively manage prescription opioid dependence acted as a gateway to heroin use-buprenorphine/naloxone treatment and recovery in a surgical patient.
    BMJ case reports, 2014, Dec-17, Volume: 2014

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Codeine; Disease Management; Female; Heroin; Heroin Dependence; Humans; Methadone; Naloxone; Opiate Substitution Treatment; Opioid-Related Disorders; Pain, Postoperative; Substance Withdrawal Syndrome; Young Adult

2014
Comparing treatment-seeking codeine users and strong opioid users: Findings from a novel case series.
    Drug and alcohol review, 2015, Volume: 34, Issue:3

    Topics: Adult; Codeine; Female; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Oxycodone; Patient Acceptance of Health Care; Retrospective Studies

2015
Severe opioid withdrawal syndrome after a single dose of nalmefene.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:8

    Topics: Adult; Alcoholism; Analgesics, Opioid; Codeine; Contraindications; Drug Interactions; Humans; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome

2015
Biocompatible Solid-Phase Microextraction Nanoelectrospray Ionization: An Unexploited Tool in Bioanalysis.
    Analytical chemistry, 2016, Jan-19, Volume: 88, Issue:2

    Topics: Amitriptyline; Biocompatible Materials; Cocaine; Codeine; Female; Healthy Volunteers; Humans; Male; Methadone; Nanotechnology; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization

2016
Refining the excretion factors of methadone and codeine for wastewater analysis - Combining data from pharmacokinetic and wastewater studies.
    Environment international, 2016, Volume: 94

    Topics: Analgesics, Opioid; Codeine; Humans; Methadone; Pyrrolidines; Wastewater; Water Pollutants, Chemical

2016
Overdose Risk in Young Children of Women Prescribed Opioids.
    Pediatrics, 2017, Volume: 139, Issue:3

    Topics: Accidents, Home; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Case-Control Studies; Child, Preschool; Codeine; Drug Overdose; Female; Hospitalization; Humans; Infant; Male; Methadone; Ontario; Oxycodone; Prescription Drugs

2017
Interpretation of Urine Drug Screens: Metabolites and Impurities.
    JAMA, 2017, Nov-07, Volume: 318, Issue:17

    Topics: Analgesics, Opioid; Codeine; False Positive Reactions; Female; Humans; Hydromorphone; Immunoassay; Mass Spectrometry; Methadone; Middle Aged; Morphine; Substance Abuse Detection

2017
Comparing methamphetamine, MDMA, cocaine, codeine and methadone use between the Auckland region and four Australian states using wastewater-based epidemiology (WBE).
    The New Zealand medical journal, 2018, 07-13, Volume: 131, Issue:1478

    Topics: Australia; Chromatography, Liquid; Cities; Cocaine; Codeine; Humans; Methadone; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; New Zealand; Substance-Related Disorders; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical

2018
Profiles of visuospatial memory dysfunction in opioid-exposed and dependent populations.
    Psychological medicine, 2019, Volume: 49, Issue:7

    Topics: Adult; Agnosia; Analgesics, Opioid; Chronic Pain; Codeine; Female; Heroin Dependence; Humans; Male; Memory Disorders; Mental Recall; Methadone; Neuropsychological Tests; Risk Factors; Tramadol; United Kingdom

2019
Evaluation of an on-site test device for the heroin metabolite 6-acetylmorphine in urine.
    Drug testing and analysis, 2019, Volume: 11, Issue:3

    Topics: Buprenorphine; Codeine; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Methadone; Morphine; Morphine Derivatives; Reagent Strips; Sensitivity and Specificity; Substance Abuse Detection

2019
Hydromorphone and codeine concentrations in oral fluid specimens from patients receiving substitution therapy with Substitol™ (morphine sulfate).
    Drug testing and analysis, 2021, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Buprenorphine; Codeine; Female; Humans; Hydromorphone; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Saliva; Substance Abuse Detection

2021
Declines and regional variation in opioid distribution by U.S. hospitals.
    Pain, 2022, 06-01, Volume: 163, Issue:6

    Topics: Analgesics, Opioid; Buprenorphine; Codeine; Hospitals; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Oxymorphone; United States

2022
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases.
    Journal of analytical toxicology, 2022, Oct-14, Volume: 46, Issue:8

    Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem

2022
Characteristics of Prescription Opioid Analgesics in Pregnancy and Risk of Neonatal Opioid Withdrawal Syndrome in Newborns.
    JAMA network open, 2022, 08-01, Volume: 5, Issue:8

    Topics: Adult; Analgesics, Opioid; Codeine; Cohort Studies; Female; Humans; Hydrocodone; Hydromorphone; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Morphine; Neonatal Abstinence Syndrome; Oxycodone; Pain; Pregnancy; Prescriptions; Substance Withdrawal Syndrome; Tramadol; United States

2022
[Estimation of the consumption level of four drugs in Beijing using wastewater-based epidemiology].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2023, May-06, Volume: 57, Issue:5

    Topics: Beijing; Codeine; Humans; Ketamine; Methadone; Sewage; Wastewater; Wastewater-Based Epidemiological Monitoring; Water Pollutants, Chemical

2023
Validation of an HPLC-HR-MS Method for the Determination and Quantification of Six Drugs (Morphine, Codeine, Methadone, Alprazolam, Clonazepam and Quetiapine) in Nails.
    Journal of analytical toxicology, 2023, May-19, Volume: 47, Issue:5

    Topics: Alprazolam; Benzodiazepines; Chromatography, High Pressure Liquid; Clonazepam; Codeine; Humans; Methadone; Morphine; Nails; Quetiapine Fumarate

2023
Detection of Three Opioids (Morphine, Codeine and Methadone) and Their Metabolites (6-Monoacetylmorphine and 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) in Larvae of
    Molecules (Basel, Switzerland), 2023, Jun-08, Volume: 28, Issue:12

    Topics: Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Codeine; Diptera; Humans; Larva; Methadone; Morphine; Morphine Derivatives

2023
Opioid poisoning in Newcastle over the last three decades: From heroin to prescription opioids.
    Emergency medicine Australasia : EMA, 2023, Volume: 35, Issue:6

    Topics: Adult; Analgesics, Opioid; Australia; Codeine; Female; Heroin; Humans; Male; Methadone; Naloxone; Oxycodone; Poisoning; Prescriptions

2023