methadone has been researched along with amitriptyline in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (41.46) | 18.7374 |
| 1990's | 3 (7.32) | 18.2507 |
| 2000's | 9 (21.95) | 29.6817 |
| 2010's | 11 (26.83) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mason, MF | 1 |
| Cramer, H; Goodwin, FK; Post, RM | 1 |
| Cantor, R | 1 |
| Cohen, MJ; Hanbury, R; Stimmel, B | 1 |
| Beckner, TF; Idsvoog, P | 1 |
| Fong, GR | 1 |
| Achté, K; Hampf, G; Henriksson, M; Kuoppasalmi, K | 1 |
| Baumann, P; Cuendet, C; Eap, CB | 1 |
| Jamron, LM; Novick, NL; Richlin, DM | 1 |
| Lewit, T | 1 |
| Cadden, JJ; Feigelson, EB | 1 |
| Hansen, V; Hjortkjaer, J; Holmblad, J; Hougs, W; Huld, T; Jorgensen, A; Lassen, N; Nielsen, IM; Nymark, M; Pedersen, V; Petersen, PV | 1 |
| Weinstock, M | 1 |
| Hartvig, P; Vessman, J | 1 |
| Garriott, JC; Stolman, A | 1 |
| Stein, JM; Warfield, CA | 1 |
| Carlson, RK; Little, TL; Tielke, VM | 1 |
| Rothrock, JF | 1 |
| Bertschy, G; Bondolfi, G; Golaz, J; Rachid, F | 1 |
| Bomsien, S; Skopp, G | 1 |
| Adelson, M; Peles, E; Schreiber, S | 1 |
| Foss, ST; Hansen, SH; Jensen, H; Kutter, JP; Pedersen-Bjergaard, S; Petersen, NJ; Skonberg, C; Snakenborg, D | 1 |
| Chen, ACh; Chen, CH; Chou, SY; Fang, KC; Fang, YC; Ho, IK; Hsiao, CF; Hsu, YT; Huang, CL; Lin, KM; Lin, YF; Liu, ML; Liu, SC; Liu, YL; Su, LW; Tian, JN; Tsou, HH; Wang, SC; Yu, CJ | 1 |
| Chen, ACh; Chen, CH; Chen, YT; Fang, CP; Ho, IK; Hsiao, CF; Hsu, YT; Huang, CL; Kuo, HW; Lin, L; Liu, CT; Liu, ML; Liu, SC; Liu, YL; Shih, YH; Su, LW; Tan, HK; Tian, JN; Tsou, HH; Wu, CS; Yang, YH; Yang, YT | 1 |
| Chatterton, C; Cirimele, V; Duez, M; Etter, M; Klinger, N; Turner, K | 1 |
| Kintz, P | 1 |
| Bojko, B; Gómez-Ríos, GA; Pawliszyn, J; Reyes-Garcés, N | 1 |
| Banchs, JE; Copeland, LA; McNeal, CJ; Stock, EM; Zeber, JE | 1 |
| Benz, P; Farkas, A; Ryan, K; Theobald, J; Zosel, A | 1 |
4 review(s) available for methadone and amitriptyline
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug impairment reviews: opiates, minor tranquilizers.
Topics: Amitriptyline; Anti-Anxiety Agents; Automobile Driving; Behavior; Desipramine; Dextropropoxyphene; Diazepam; Ethanol; Humans; Imipramine; Lithium; Methadone; Motor Skills; Narcotics; Task Performance and Analysis | 1977 |
[Pulmonary diseases due to drugs. II].
Topics: Amines; Amitriptyline; Beclomethasone; Drug-Related Side Effects and Adverse Reactions; Heroin; Humans; Hydantoins; Lung Diseases; Methadone; Naloxone; Oxazoles; Pneumonia, Aspiration; Respiratory Therapy; Sulfasalazine; Ventilators, Mechanical | 1974 |
1 trial(s) available for methadone and amitriptyline
| Article | Year |
|---|---|
Management of chronic daily headache utilizing a uniform treatment pathway.
Topics: Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Drug Therapy, Combination; Female; GABA Agents; Headache; Humans; Male; Methadone; Middle Aged; Phenelzine; Valproic Acid | 1999 |
36 other study(ies) available for methadone and amitriptyline
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Cyclic AMP in cerebrospinal fluid of manic and depressive patients.
Topics: Administration, Oral; Amitriptyline; Bipolar Disorder; Cyclic AMP; Depression; Humans; Imipramine; Lithium; Methadone; Methyltyrosines; Physical Exertion; Probenecid; Tryptophan | 1977 |
Methadone maintenance and amitriptyline.
Topics: Amitriptyline; Humans; Methadone; Substance-Related Disorders | 1979 |
Abuse of amitriptyline.
Topics: Amitriptyline; Depression; Heroin Dependence; Humans; Methadone; Self Medication; Substance Withdrawal Syndrome; Substance-Related Disorders; United States | 1978 |
Drug use and distribution in a pain rehabilitation center.
Topics: Adult; Amitriptyline; Barbiturates; Chronic Disease; Diet; Female; Formularies, Hospital as Topic; Humans; Male; Methadone; Pain; Pharmaceutical Preparations; Phenytoin; Snake Venoms | 1975 |
Letter: Drug use in a pain rehabilitation center.
Topics: Amitriptyline; Chronic Disease; Drug Combinations; Humans; Methadone; Pain; Phenytoin; Snake Venoms | 1975 |
Chronic facial pain together with severe depression is responsive to electroconvulsive therapy. A case report.
Topics: Amitriptyline; Chronic Disease; Clonazepam; Depressive Disorder; Electroconvulsive Therapy; Facial Pain; Female; Humans; Methadone; Middle Aged | 1992 |
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine | 1988 |
Cancer pain control with a combination of methadone, amitriptyline, and non-narcotic analgesic therapy: a case series analysis.
Topics: Adolescent; Adult; Aged; Amitriptyline; Analgesics; Drug Therapy, Combination; Female; Humans; Male; Methadone; Middle Aged; Neoplasms; Pain, Intractable | 1987 |
Changing patterns of drug abuse in New York City.
Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Antipsychotic Agents; Barbiturates; Codeine; Dextropropoxyphene; Female; Glutethimide; Heroin Dependence; Humans; Male; Methadone; Morphine; New York City; Phenothiazines; Phenytoin; Quinine; Substance-Related Disorders | 1974 |
Pharmacological studies of a new series of bicyclic thymoleptics.
Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Behavior, Animal; Benzofurans; Cocaine; Drug Antagonism; Drug Synergism; Guinea Pigs; Heterocyclic Compounds; Ileum; Indoles; Male; Methadone; Mice; Norepinephrine; Oxazines; Parasympatholytics; Polycyclic Compounds; Quinolines; Reserpine | 1966 |
The role of the sympathetic nervous system in mediating the action of analgesic drugs on the lens.
Topics: Amitriptyline; Amphetamine; Animals; Bretylium Compounds; Cocaine; Dopamine; Ephedrine; Epinephrine; Guanethidine; Imipramine; Iproniazid; Lens, Crystalline; Metaraminol; Methadone; Mice; Nialamide; Norepinephrine; Phenylephrine; Reserpine; Sympathetic Nervous System; Synephrine | 1968 |
Electron capture gas chromatography of tertiary amines after a demethylation reaction to secondary amines. II. Studies of different chloroformates and alternative hydrolysis procedures.
Topics: Acylation; Amitriptyline; Chromatography, Gas; Diphenhydramine; Formates; Hydrocarbons, Brominated; Hydrocarbons, Chlorinated; Hydrolysis; Imipramine; Mass Spectrometry; Methadone; Methods; Methylamines; Propylamines; Time Factors | 1974 |
Detection of some psychotherapeutic drugs and their metabolites in urine.
Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1971 |
The pain clinic: the use of systemic analgesics.
Topics: Adult; Aged; Amitriptyline; Analgesics; Anti-Inflammatory Agents; Anticonvulsants; Bone Neoplasms; Drug Synergism; Female; Humans; Lymphoma; Male; Methadone; Middle Aged; Opium; Pain, Intractable; Palliative Care; Pancreatic Neoplasms; Prostatic Neoplasms; Psychotropic Drugs | 1982 |
Stability of methadone pain cocktails.
Topics: Amitriptyline; Drug Combinations; Drug Stability; Hydroxyzine; Methadone; Phenobarbital | 1982 |
Drugs for pain.
Topics: Acetaminophen; Administration, Oral; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Aspirin; Constipation; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Tolerance; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Ketorolac; Levorphanol; Meperidine; Methadone; Morphine; Narcotic Antagonists; Narcotics; Pain; Tolmetin; Tramadol | 1998 |
Induction of a mixed depressive episode during rTMS treatment in a patient with refractory major depression.
Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antimanic Agents; Depressive Disorder, Major; Female; Humans; Methadone; Mood Disorders; Narcotics; Opipramol; Paroxetine; Prazepam; Psychiatric Status Rating Scales; Serotonin Syndrome; Severity of Illness Index; Substance-Related Disorders; Transcranial Magnetic Stimulation; Trazodone; Valproic Acid | 2006 |
An in vitro approach to potential methadone metabolic-inhibition interactions.
Topics: Algorithms; Amitriptyline; Analgesics, Opioid; Atomoxetine Hydrochloride; Chromatography, Liquid; Citalopram; Clozapine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Isoenzymes; Kinetics; Methadone; Methylation; N-Methyl-3,4-methylenedioxyamphetamine; Oxidoreductases, N-Demethylating; Propylamines; Psychotropic Drugs; Pyridines; Pyrrolidines; Tandem Mass Spectrometry; Zolpidem | 2007 |
Tricyclic antidepressants abuse, with or without benzodiazepines abuse, in former heroin addicts currently in methadone maintenance treatment (MMT).
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Benzodiazepines; Cross-Sectional Studies; Data Interpretation, Statistical; Depressive Disorder; Electrocardiography; Female; Heroin Dependence; Humans; Male; Methadone; Multivariate Analysis; Narcotics; Odds Ratio; Psychiatric Status Rating Scales; Psychotic Disorders; Substance Abuse Detection; Substance-Related Disorders | 2008 |
On-chip electro membrane extraction with online ultraviolet and mass spectrometric detection.
Topics: Amitriptyline; Animals; Chemical Fractionation; Male; Membranes, Artificial; Methadone; Microfluidic Analytical Techniques; Microsomes, Liver; Online Systems; Polypropylenes; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2011 |
Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients.
Topics: Adult; Amitriptyline; Areca; Biomarkers, Pharmacological; Cytochrome P-450 CYP3A; Female; Genetic Association Studies; Heart Rate; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Polymorphism, Single Nucleotide; Substance Withdrawal Syndrome | 2011 |
UGT2B7 genetic polymorphisms are associated with the withdrawal symptoms in methadone maintenance patients.
Topics: Adult; Amitriptyline; Female; Genetic Association Studies; Glucuronosyltransferase; Haplotypes; Heroin Dependence; Humans; Linkage Disequilibrium; Male; Methadone; Middle Aged; Morphine; Polymorphism, Single Nucleotide; Pyrrolidines; Substance Withdrawal Syndrome; Taiwan | 2012 |
Interpretation of pharmaceutical drug concentrations in young children's head hair.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child of Impaired Parents; Child, Preschool; Chromatography, Liquid; Female; Forensic Toxicology; Hair; Humans; Infant; Methadone; Narcotics; Nortriptyline; Pyrrolidines; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol | 2014 |
Contribution of in utero drug exposure when interpreting hair results in young children.
Topics: Amitriptyline; Bromazepam; Cannabinoids; Diazepam; Diphenhydramine; Female; Forensic Toxicology; Hair; Heroin; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Methadone; Narcotics; Pregnancy; Substance-Related Disorders; Tramadol | 2015 |
Biocompatible Solid-Phase Microextraction Nanoelectrospray Ionization: An Unexploited Tool in Bioanalysis.
Topics: Amitriptyline; Biocompatible Materials; Cocaine; Codeine; Female; Healthy Volunteers; Humans; Male; Methadone; Nanotechnology; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2016 |
Psychotropic Pharmacotherapy Associated With QT Prolongation Among Veterans With Posttraumatic Stress Disorder.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Arrhythmias, Cardiac; Buspirone; Female; Humans; Male; Methadone; Middle Aged; Piperazines; Psychotropic Drugs; Quetiapine Fumarate; Sotalol; Stress Disorders, Post-Traumatic; Thiazoles; Veterans; Young Adult | 2018 |
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
Topics: Amitriptyline; Arrhythmias, Cardiac; Diphenhydramine; Electrocardiography; Flecainide; Humans; Long QT Syndrome; Methadone; Mirtazapine; Poison Control Centers; Retrospective Studies; Risk Factors; Tachycardia, Ventricular; Torsades de Pointes; Trazodone; Ventricular Fibrillation | 2022 |